BB-norm@ldeleger:BB-norm-3544198 JSONTXT

{"project":"bionlp-ost-19-BB-norm-dev","denotations":[{"id":"T1","span":{"begin":0,"end":102},"obj":"Title"},{"id":"T3","span":{"begin":40,"end":60},"obj":"Microorganism"},{"id":"T4","span":{"begin":76,"end":101},"obj":"Habitat"},{"id":"T5","span":{"begin":85,"end":101},"obj":"Habitat"},{"id":"T2","span":{"begin":103,"end":733},"obj":"Paragraph"},{"id":"T6","span":{"begin":163,"end":183},"obj":"Microorganism"},{"id":"T7","span":{"begin":210,"end":235},"obj":"Habitat"},{"id":"T8","span":{"begin":219,"end":235},"obj":"Habitat"},{"id":"T9","span":{"begin":309,"end":314},"obj":"Habitat"},{"id":"T10","span":{"begin":465,"end":485},"obj":"Habitat"},{"id":"T11","span":{"begin":474,"end":485},"obj":"Habitat"},{"id":"T12","span":{"begin":558,"end":578},"obj":"Habitat"},{"id":"T13","span":{"begin":712,"end":732},"obj":"Habitat"},{"id":"T14","span":{"begin":721,"end":732},"obj":"Habitat"}],"attributes":[{"id":"A3","pred":"OntoBiotope","subj":"T5","obj":"OBT:003269"},{"id":"A1","pred":"NCBI_Taxonomy","subj":"T3","obj":"1769"},{"id":"A7","pred":"OntoBiotope","subj":"T9","obj":"OBT:001367"},{"id":"A2","pred":"OntoBiotope","subj":"T4","obj":"OBT:001367"},{"id":"A6","pred":"OntoBiotope","subj":"T8","obj":"OBT:003269"},{"id":"A8","pred":"OntoBiotope","subj":"T10","obj":"OBT:001367"},{"id":"A9","pred":"OntoBiotope","subj":"T11","obj":"OBT:003269"},{"id":"A10","pred":"OntoBiotope","subj":"T12","obj":"OBT:000007"},{"id":"A4","pred":"NCBI_Taxonomy","subj":"T6","obj":"1769"},{"id":"A12","pred":"OntoBiotope","subj":"T14","obj":"OBT:003269"},{"id":"A5","pred":"OntoBiotope","subj":"T7","obj":"OBT:001367"},{"id":"A11","pred":"OntoBiotope","subj":"T13","obj":"OBT:001367"}],"text":"Methods for the detection of a specific Mycobacterium leprae antigen in the urine of leprosy patients.\nTwo methods for detecting the phenolic glycolipid, PGL-1, a Mycobacterium leprae-specific molecule, in the urine of leprosy patients are described. Both methods rely on the 100-fold preconcentration of the urine, which can be accomplished by a single-step ultrafiltration procedure. The equivalent of approximately 2.5 micrograms of PGL-1/ml was detected in the urine of LL patients with an inhibition ELISA. The second method, a direct dot-blot assay on nitrocellulose paper, was much simpler and more sensitive. As little as 3 ng of antigen was detected by the dot-blot technique. PGL-1 was detected in the urine of LL patients.\n\n"}