BB-norm@ldeleger:BB-norm-19339076 JSONTXT

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bionlp-ost-19-BB-norm-dev

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Id Subject Object Predicate Lexical cue NCBI_Taxonomy OntoBiotope
T1 0-132 Title denotes Bile resistance in Lactococcus lactis strains varies with cellular fatty acid composition: analysis by using different growth media.
T3 0-15 Phenotype denotes Bile resistance OBT:000152
T4 0-4 Habitat denotes Bile OBT:000514
T5 19-37 Microorganism denotes Lactococcus lactis 1358
T2 133-2382 Paragraph denotes Bile resistance is one of the basic characteristics of probiotic bacteria. The aim of this study was to investigate the characteristics of bile resistance in lactococci by studying the relationship between bile resistance and cellular fatty acid composition in lactococcci grown on different media. We determined the bile resistance of 14 strains in lactose-free M17 medium supplemented with either glucose only (GM17) or lactose only (LM17). Gas chromatographic analyses of free lipids extracted from the tested strains were used for determining their fatty acid composition. A correlation analysis of all strains grown in both media revealed significant positive correlations between bile resistance and relative contents of hexadecanoic acid and octadecenoic acid, and negative correlations between bile resistance and relative contents of hexadecenoic acid and C-19 cyclopropane fatty acid. It is also a fact that the fatty acids associated with bile resistance depended on species, strain, and/or growth medium. In L. lactis subsp. cremoris strains grown in GM17 medium, the bile-resistant strains had significantly more octadecenoic acid than the bile-sensitive strains. In LM17 medium, bile-resistant strains had significantly more octadecenoic acid and significantly less C-19 cyclopropane fatty acid than the bile-sensitive strains. In L. lactis subsp. lactis strains, bile resistances of some of the tested strains were altered by growth medium. Some strains were resistant to bile in GM17 medium but sensitive to bile in LM17 medium. Some strains were resistant in both media tested. The strains grown in GM17 medium had significantly more hexadecanoic acid and octadecenoic acid, and significantly less tetradecanoic acid, octadecadienoic acid and C-19 cyclopropane fatty acid than the strains grown in LM17 medium. In conclusion, the fatty acid compositions of the bile-resistant lactococci differed from those of the bile-sensitive ones. More importantly, our data suggest that altering their fatty acid composition (i.e. increased hexadecanoic acid and octadecenoic acid and decreased hexadecenoic acid and C-19 cyclopropane fatty acid) by changing growth conditions may be a useful way to enhance their bile resistance in lactococci.
T6 133-148 Phenotype denotes Bile resistance OBT:000152
T7 133-137 Habitat denotes Bile OBT:000514
T8 188-197 Phenotype denotes probiotic OBT:000827
T9 272-287 Phenotype denotes bile resistance OBT:000152
T10 272-276 Habitat denotes bile OBT:000514
T11 291-301 Microorganism denotes lactococci 1357
T12 339-354 Phenotype denotes bile resistance OBT:000152
T13 339-343 Habitat denotes bile OBT:000514
T14 394-405 Microorganism denotes lactococcci 1357
T15 450-465 Phenotype denotes bile resistance OBT:000152
T16 450-454 Habitat denotes bile OBT:000514
T17-0 483-524 _FRAGMENT denotes lactose-free M17 medium supplemented with OBT:000007
T17-1 532-551 Habitat denotes glucose only (GM17)
T18-0 483-524 _FRAGMENT denotes lactose-free M17 medium supplemented with OBT:000007
T18-1 555-574 Habitat denotes lactose only (LM17)
T19 819-834 Phenotype denotes bile resistance OBT:000152
T20 819-823 Habitat denotes bile OBT:000514
T21 935-950 Phenotype denotes bile resistance OBT:000152
T22 935-939 Habitat denotes bile OBT:000514
T23 1083-1098 Phenotype denotes bile resistance OBT:000152
T24 1083-1087 Habitat denotes bile OBT:000514
T25 1153-1178 Microorganism denotes L. lactis subsp. cremoris 1359
T26 1196-1207 Habitat denotes GM17 medium OBT:000007
T27 1213-1227 Phenotype denotes bile-resistant OBT:000152
T28 1213-1217 Habitat denotes bile OBT:000514
T29 1286-1300 Phenotype denotes bile-sensitive OBT:000153
T30 1286-1290 Habitat denotes bile OBT:000514
T31 1313-1324 Habitat denotes LM17 medium OBT:000007
T32 1326-1340 Phenotype denotes bile-resistant OBT:000152
T33 1326-1330 Habitat denotes bile OBT:000514
T34 1451-1465 Phenotype denotes bile-sensitive OBT:000153
T35 1451-1455 Habitat denotes bile OBT:000514
T36 1478-1501 Microorganism denotes L. lactis subsp. lactis 1360
T37 1511-1527 Phenotype denotes bile resistances OBT:000152
T38 1511-1515 Habitat denotes bile OBT:000514
T39 1607-1624 Phenotype denotes resistant to bile OBT:000152
T40 1620-1624 Habitat denotes bile OBT:000514
T41 1628-1639 Habitat denotes GM17 medium OBT:000007
T42 1644-1661 Phenotype denotes sensitive to bile OBT:000153
T43 1657-1661 Habitat denotes bile OBT:000514
T44 1665-1676 Habitat denotes LM17 medium OBT:000007
T45 1696-1705 Phenotype denotes resistant OBT:000152
T46 1749-1760 Habitat denotes GM17 medium OBT:000007
T47 1948-1959 Habitat denotes LM17 medium OBT:000007
T48 2011-2025 Phenotype denotes bile-resistant OBT:000152
T49 2011-2015 Habitat denotes bile OBT:000514
T50 2026-2036 Microorganism denotes lactococci 1357
T51 2064-2078 Phenotype denotes bile-sensitive OBT:000153
T52 2064-2068 Habitat denotes bile OBT:000514
T53 2352-2367 Phenotype denotes bile resistance OBT:000152
T54 2352-2356 Habitat denotes bile OBT:000514
T55 2371-2381 Microorganism denotes lactococci 1357
C-T17-0 T17-1 T17-0 _lexicallyChainedTo glucose only (GM17),lactose-free M17 medium supplemented with
C-T18-0 T18-1 T18-0 _lexicallyChainedTo lactose only (LM17),lactose-free M17 medium supplemented with