BB-norm+ner@ldeleger:BB-norm+ner-10665543 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/BB-norm+ner@ldeleger/sourceid/BB-norm+ner-10665543","sourcedb":"BB-norm+ner@ldeleger","sourceid":"BB-norm+ner-10665543","text":"Evaluation of three Brucella soluble antigens used in an indirect Elisa to discriminate S19 vaccinated from naturally infected cattle.\nAn O-polysaccharide (O-chain) and a hot-water extracted polysaccharide (PS), both obtained from Brucella abortus 1119-3, and a B. melitensis 16M native hapten (NH) were evaluated by indirect enzyme linked immunosorbent assay (ELISA) on three groups of cattle sera. The sera tested were: (a) 75 sera from cows naturally infected with B. abortus; (b) 130 sera from non-infected and non-vaccinated cattle; and (c) 61 sera from non-infected heifers recently vaccinated with B. abortus Strain 19 (S19). Sensitivity (Se), specificity (Sp) and the capability to discriminate vaccinated cattle (ADV) were determined. Using PS antigen, Se was 100% and the Sp was 97.7%, while the highest Sp was obtained by using the O-chain (99.2% ). For the NH antigen, Se was 94.7% and the Sp was 90.0%. The ADV of the three antigens was approximately 85%. Statistical analysis showed significant differences between O-chain/PS and O-chain/NH antigens. The agreement among antigens determined by kappa coefficient was 0.899 for O-chain/PS, 0.845 for O-chain/NH and 0.795 for PS/NH.\n\n","tracks":[{"project":"bionlp-ost-19-BB-norm-ner-test","denotations":[{"id":"T1","span":{"begin":0,"end":134},"obj":"Title"},{"id":"T2","span":{"begin":135,"end":1193},"obj":"Paragraph"}],"attributes":[{"subj":"T1","pred":"source","obj":"bionlp-ost-19-BB-norm-ner-test"},{"subj":"T2","pred":"source","obj":"bionlp-ost-19-BB-norm-ner-test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"bionlp-ost-19-BB-norm-ner-test","color":"#ec93d5","default":true}]}]}}