BB-kb+ner@ldeleger:BB-kb+ner-20580604 JSONTXT

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bionlp-ost-19-BB-kb-ner-dev

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Id Subject Object Predicate Lexical cue NCBI_Taxonomy OntoBiotope
T1 0-212 Title denotes Effects of a probiotic fermented milk beverage containing Lactobacillus casei strain Shirota on defecation frequency, intestinal microbiota, and the intestinal environment of healthy individuals with soft stools.
T2 213-1814 Paragraph denotes The effects of drinking a fermented milk beverage that contains Lactobacillus casei strain Shirota (LcS) at 40 billion bacterial cells/bottle for 4 weeks (probiotics, 1 bottle/day) on defecation frequency, intestinal microbiota and the intestinal environment of healthy individuals with soft stools were evaluated. Thirty-four healthy adults who had soft stools were randomised into 2 groups, and the effects of a regular 4-week intake of probiotics were evaluated by a placebo-controlled, double-blind, parallel-group comparative design. Defecation frequency significantly decreased after the 4-week intake period compared with before the probiotic treatment. The stool quality significantly improved (hardened) compared to the placebo. Also, the water content of the stools was lower in the probiotic group than in the placebo group. Live LcS was recovered at 6.9 ± 1.3 and 7.2 ± 0.8 log(10) CFU per 1g of stool after 2 and 4 weeks, respectively, of probiotic treatment. The number of bifidobacteria in the stools also increased significantly compared with the level before starting the probiotics. The organic acid levels (total, acetic acid, propionic acid, and butyric acid) significantly increased compared with the level before intake in both the probiotic and placebo groups, but they returned to the original levels after the end of the intake period. These results suggest that probiotic fermented milk beverage has an intestine-conditioning effect by improving the frequency of defecation and stool quality and increasing the intrinsic bifidobacteria in healthy individuals with soft stool.
T3 13-46 Habitat denotes probiotic fermented milk beverage OBT:001269|OBT:003146|OBT:003343
T4 58-92 Microorganism denotes Lactobacillus casei strain Shirota 1582
T6 118-139 Habitat denotes intestinal microbiota OBT:000113
T5 118-128 Habitat denotes intestinal OBT:002810
T7 149-211 Habitat denotes intestinal environment of healthy individuals with soft stools OBT:002810
T8 175-211 Habitat denotes healthy individuals with soft stools OBT:002712
T9 200-211 Habitat denotes soft stools OBT:001102
T10 239-262 Habitat denotes fermented milk beverage OBT:003146|OBT:003343
T11 277-311 Microorganism denotes Lactobacillus casei strain Shirota 1582
T12 313-316 Microorganism denotes LcS 1582
T13 348-354 Habitat denotes bottle OBT:003146
T14 368-378 Habitat denotes probiotics OBT:001269
T15 382-388 Habitat denotes bottle OBT:003146|OBT:001269
T16 419-440 Habitat denotes intestinal microbiota OBT:000113
T17 419-429 Habitat denotes intestinal OBT:002810
T18 449-511 Habitat denotes intestinal environment of healthy individuals with soft stools OBT:002810
T19 475-511 Habitat denotes healthy individuals with soft stools OBT:002712
T20 500-511 Habitat denotes soft stools OBT:001102
T21 540-554 Habitat denotes healthy adults OBT:002712|OBT:003245
T22 563-574 Habitat denotes soft stools OBT:001102
T23 652-662 Habitat denotes probiotics OBT:001269
T24 853-862 Habitat denotes probiotic OBT:001269
T25 878-883 Habitat denotes stool OBT:001102
T26 961-988 Habitat denotes water content of the stools OBT:000215
T27 982-988 Habitat denotes stools OBT:001102
T29 1006-1021 Habitat denotes probiotic group OBT:003245
T28 1006-1015 Habitat denotes probiotic OBT:001269
T30 1034-1047 Habitat denotes placebo group OBT:003245
T31 1054-1057 Microorganism denotes LcS 1582
T32 1121-1126 Habitat denotes stool OBT:001102
T33 1165-1174 Habitat denotes probiotic OBT:001269
T34 1200-1214 Microorganism denotes bifidobacteria 1678
T35 1222-1228 Habitat denotes stools OBT:001102
T36 1302-1312 Habitat denotes probiotics OBT:001269
T38 1467-1476 Habitat denotes probiotic OBT:001269
T37-0 1467-1476 _FRAGMENT denotes probiotic OBT:003245
T37-1 1489-1495 Habitat denotes groups
T39 1481-1495 Habitat denotes placebo groups OBT:003245
T40 1601-1634 Habitat denotes probiotic fermented milk beverage OBT:001269|OBT:003146|OBT:003343
T41 1642-1651 Habitat denotes intestine OBT:002810
T42 1717-1722 Habitat denotes stool OBT:001102
T43 1760-1774 Microorganism denotes bifidobacteria 1678
T44 1778-1813 Habitat denotes healthy individuals with soft stool OBT:002712
T45 1803-1813 Habitat denotes soft stool OBT:001102
E1 58-92 Lives_In denotes Lactobacillus casei strain Shirota
E2 277-311 Lives_In denotes Lactobacillus casei strain Shirota
E3 277-311 Lives_In denotes Lactobacillus casei strain Shirota
E4 277-311 Lives_In denotes Lactobacillus casei strain Shirota
E5 277-311 Lives_In denotes Lactobacillus casei strain Shirota
E6 1054-1057 Lives_In denotes LcS
E7 1200-1214 Lives_In denotes bifidobacteria
E8 1760-1774 Lives_In denotes bifidobacteria
R1 E1 T4 Microorganism Lactobacillus casei strain Shirota,Lactobacillus casei strain Shirota
R2 E1 T3 Location Lactobacillus casei strain Shirota,probiotic fermented milk beverage
R3 E2 T11 Microorganism Lactobacillus casei strain Shirota,Lactobacillus casei strain Shirota
R4 E2 T15 Location Lactobacillus casei strain Shirota,bottle
R5 E3 T11 Microorganism Lactobacillus casei strain Shirota,Lactobacillus casei strain Shirota
R6 E3 T10 Location Lactobacillus casei strain Shirota,fermented milk beverage
R7 E4 T11 Microorganism Lactobacillus casei strain Shirota,Lactobacillus casei strain Shirota
R8 E4 T14 Location Lactobacillus casei strain Shirota,probiotics
R9 E5 T11 Microorganism Lactobacillus casei strain Shirota,Lactobacillus casei strain Shirota
R10 E5 T13 Location Lactobacillus casei strain Shirota,bottle
R11 E6 T31 Microorganism LcS,LcS
R12 E6 T32 Location LcS,stool
R13 E7 T34 Microorganism bifidobacteria,bifidobacteria
R14 E7 T35 Location bifidobacteria,stools
R15 E8 T43 Microorganism bifidobacteria,bifidobacteria
R16 E8 T44 Location bifidobacteria,healthy individuals with soft stool
C-T37-0 T37-1 T37-0 _lexicallyChainedTo groups,probiotic