BB-kb+ner@ldeleger:BB-kb+ner-10658649 JSONTXT

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bionlp-ost-19-BB-kb-ner-train

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue NCBI_Taxonomy OntoBiotope
T1 0-108 Title denotes Identification of a novel glycoprotein-binding activity in Streptococcus pyogenes regulated by the mga gene.
T2 109-1148 Paragraph denotes The interaction between Streptococcus pyogenes and the host cell surface is not completely understood. Characterization of the adhesion mechanisms of the bacterium to the host cell surface is needed in order to develop new vaccines and anti-adhesion drugs. The presence of glycoprotein-binding activities among streptococcal strains was investigated. An activity binding to thyroglobulin, fetuin, asialofetuin and mucin but not non-glycosylated proteins was found to be present in the majority of the S. pyogenes strains studied. Cross-inhibition experiments suggested that the glycoproteins share a common structure recognized by the bacteria. The glycoprotein-binding activity was found to be proteinaceous, tightly attached to the bacterial surface and it also mediated the adherence of bacteria to solid surfaces coated with glycoproteins. The activity was found by transposon mutagenesis and complementation to be regulated by the multiple-gene regulator Mga, which has been implicated as a regulator of S. pyogenes virulence factors.
T3 26-55 Phenotype denotes glycoprotein-binding activity OBT:000019
T4 59-81 Microorganism denotes Streptococcus pyogenes 1314
T5 133-155 Microorganism denotes Streptococcus pyogenes 1314
T6 164-173 Habitat denotes host cell OBT:000061
T7 236-255 Phenotype denotes adhesion mechanisms OBT:000029
T8 280-289 Habitat denotes host cell OBT:000061
T9 332-340 Habitat denotes vaccines OBT:000464
T10 382-413 Phenotype denotes glycoprotein-binding activities OBT:000019
T11 420-433 Microorganism denotes streptococcal 1314
T14 463-496 Phenotype denotes activity binding to thyroglobulin OBT:000019
T12-0 463-482 _FRAGMENT denotes activity binding to OBT:000019
T12-1 498-504 Phenotype denotes fetuin
T13-0 463-482 _FRAGMENT denotes activity binding to OBT:000019
T13-1 506-518 Phenotype denotes asialofetuin
T15-0 463-482 _FRAGMENT denotes activity binding to OBT:000019
T15-1 523-528 Phenotype denotes mucin
T16 610-621 Microorganism denotes S. pyogenes 1314
T17 758-787 Phenotype denotes glycoprotein-binding activity OBT:000019
T18 886-895 Phenotype denotes adherence OBT:000029
T19 1118-1129 Microorganism denotes S. pyogenes 1314
T20 1130-1139 Phenotype denotes virulence OBT:000375
E1 59-81 Exhibits denotes Streptococcus pyogenes
E2 133-155 Exhibits denotes Streptococcus pyogenes
E3 610-621 Exhibits denotes S. pyogenes
E4 610-621 Exhibits denotes S. pyogenes
E5 610-621 Exhibits denotes S. pyogenes
E6 610-621 Exhibits denotes S. pyogenes
E7 1118-1129 Exhibits denotes S. pyogenes
R1 E1 T4 Microorganism Streptococcus pyogenes,Streptococcus pyogenes
R2 E1 T3 Property Streptococcus pyogenes,glycoprotein-binding activity
R3 E2 T5 Microorganism Streptococcus pyogenes,Streptococcus pyogenes
R4 E2 T7 Property Streptococcus pyogenes,adhesion mechanisms
R5 E3 T16 Microorganism S. pyogenes,S. pyogenes
R6 E3 T13-0 Property S. pyogenes,activity binding to
R7 E4 T16 Microorganism S. pyogenes,S. pyogenes
R8 E4 T15-0 Property S. pyogenes,activity binding to
R9 E5 T16 Microorganism S. pyogenes,S. pyogenes
R10 E5 T12-0 Property S. pyogenes,activity binding to
R11 E6 T16 Microorganism S. pyogenes,S. pyogenes
R12 E6 T14 Property S. pyogenes,activity binding to thyroglobulin
R13 E7 T19 Microorganism S. pyogenes,S. pyogenes
R14 E7 T20 Property S. pyogenes,virulence
C-T12-0 T12-1 T12-0 _lexicallyChainedTo fetuin,activity binding to
C-T13-0 T13-1 T13-0 _lexicallyChainedTo asialofetuin,activity binding to
C-T15-0 T15-1 T15-0 _lexicallyChainedTo mucin,activity binding to