| Id |
Subject |
Object |
Predicate |
Lexical cue |
ForCovid19 |
Memo |
all_replicate |
correct/standard/original word |
tao:has_database_id |
| T1 |
98-108 |
Species |
denotes |
SARS-CoV-2 |
|
|
t |
|
Tax:2697049 |
| T10 |
77-85 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T100 |
1102-1113 |
Interact |
denotes |
interacting |
|
|
|
|
|
| T101 |
1206-1210 |
Gene |
denotes |
ACE2 |
|
|
|
|
Gene:59272 |
| T102 |
2476-2480 |
Gene |
denotes |
ACE2 |
|
|
|
|
Gene:59272 |
| T103 |
2805-2809 |
Gene |
denotes |
ACE2 |
|
|
|
|
Gene:59272 |
| T104 |
3332-3336 |
Gene |
denotes |
ACE2 |
|
|
|
|
Gene:59272 |
| T105 |
3347-3351 |
Gene |
denotes |
ACE2 |
|
|
|
|
Gene:59272 |
| T106 |
4089-4093 |
Gene |
denotes |
ACE2 |
|
|
|
|
Gene:59272 |
| T107 |
4945-4949 |
Gene |
denotes |
ACE2 |
|
|
|
|
Gene:59272 |
| T108 |
5315-5319 |
Gene |
denotes |
ACE2 |
|
|
|
|
Gene:59272 |
| T109 |
5741-5745 |
Gene |
denotes |
ACE2 |
|
|
|
|
Gene:59272 |
| T11 |
142-150 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T110 |
1173-1204 |
Gene |
denotes |
Angiotensin-Converting Enzyme 2 |
|
|
|
|
Gene:59272 |
| T111 |
1237-1246 |
Express |
denotes |
expressed |
|
|
|
|
|
| T112 |
2673-2682 |
Express |
denotes |
expressed |
|
|
|
|
|
| T12 |
764-772 |
Disease |
denotes |
COVID-19 |
|
|
t |
|
MESH:D000086382 |
| T13 |
1040-1048 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T14 |
1455-1463 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T15 |
1788-1796 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T16 |
1994-2002 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T17 |
2132-2140 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T18 |
3834-3842 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T19 |
4451-4459 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T2 |
129-139 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
|
Tax:2697049 |
| T20 |
4594-4602 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T21 |
4669-4677 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T22 |
4857-4865 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T23 |
5028-5036 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T24 |
5666-5674 |
Disease |
denotes |
COVID-19 |
|
|
|
|
MESH:D000086382 |
| T25 |
19-45 |
Biological |
denotes |
'Renin-Angiotensin' System |
|
|
|
|
|
| T26 |
52-67 |
Chemical |
denotes |
Candidate Drugs |
drug |
|
|
|
|
| T27 |
4890-4898 |
Disease |
denotes |
infected |
|
|
|
|
MESH:D007239 |
| T28 |
109-117 |
Disease |
denotes |
infected |
|
|
t |
|
MESH:D007239 |
| T29 |
1866-1874 |
Disease |
denotes |
infected |
|
|
t |
|
MESH:D007239 |
| T3 |
998-1008 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
|
Tax:2697049 |
| T30 |
1875-1882 |
Species |
denotes |
persons |
|
|
|
|
Tax:9606 |
| T31 |
118-126 |
Species |
denotes |
patients |
|
|
|
|
Tax:9606 |
| T32 |
773-781 |
Species |
denotes |
patients |
|
|
|
|
Tax:9606 |
| T33 |
4603-4611 |
Species |
denotes |
patients |
|
|
|
|
Tax:9606 |
| T34 |
159-185 |
Biological |
denotes |
'Renin-Angiotensin' System |
|
|
|
|
|
| T35 |
2152-2178 |
Biological |
denotes |
'Renin-Angiotensin' System |
|
|
|
|
|
| T36 |
2180-2183 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T37 |
229-232 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T38 |
558-561 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T39 |
609-612 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T4 |
1436-1446 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
|
Tax:2697049 |
| T40 |
1091-1094 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T41 |
1848-1851 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T42 |
1891-1894 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T43 |
1965-1968 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T44 |
2107-2110 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T45 |
2206-2209 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T46 |
2217-2220 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T47 |
2525-2528 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T48 |
2751-2754 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T49 |
3459-3462 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T5 |
1855-1865 |
Species |
denotes |
SARS-CoV-2 |
|
|
t |
|
Tax:2697049 |
| T50 |
3696-3699 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T51 |
3792-3795 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T52 |
3906-3909 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T53 |
4330-4333 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T54 |
4403-4406 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T55 |
4519-4533 |
Chemical |
denotes |
RAS inhibitors |
inhibitor|drug |
|
|
|
|
| T56 |
4633-4645 |
Chemical |
denotes |
RAS blockers |
inhibitor|drug |
|
|
|
|
| T57 |
4712-4726 |
Chemical |
denotes |
RAS inhibitors |
inhibitor|drug |
|
|
|
|
| T58 |
4764-4767 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T59 |
4920-4923 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T6 |
2482-2492 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
|
Tax:2697049 |
| T60 |
5066-5069 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T61 |
5565-5568 |
Biological |
denotes |
RAS |
|
|
|
|
|
| T62 |
201-227 |
Biological |
denotes |
'Renin-Angiotensin' system |
|
|
|
|
|
| T63 |
0-18 |
NegativeRegulation |
denotes |
Counter-regulatory |
|
|
t |
|
|
| T64 |
2187-2205 |
NegativeRegulation |
denotes |
Counter-regulatory |
|
|
|
|
|
| T65 |
255-293 |
Biological |
denotes |
'Renin-Angiotensin-Aldosterone' system |
|
|
|
|
|
| T66 |
408-417 |
Function |
denotes |
functions |
|
|
|
|
|
| T67 |
368-373 |
Biological |
denotes |
renal |
|
|
|
|
|
| T68 |
693-698 |
Biological |
denotes |
renal |
|
|
|
|
|
| T69 |
1316-1329 |
Biological |
denotes |
renal tubules |
|
|
|
|
|
| T7 |
4365-4375 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
|
Tax:2697049 |
| T70 |
375-389 |
Biological |
denotes |
cardiovascular |
|
|
|
|
|
| T71 |
394-407 |
Biological |
denotes |
innate immune |
|
|
|
|
|
| T72 |
355-364 |
Regulation |
denotes |
regulator |
|
|
|
|
|
| T78 |
3885-3905 |
NegativeRegulation |
denotes |
'counter-regulatory' |
|
|
|
|
|
| T79 |
5544-5564 |
NegativeRegulation |
denotes |
'counter-regulatory' |
|
|
|
|
|
| T8 |
4879-4889 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
|
Tax:2697049 |
| T80 |
4899-4905 |
Species |
denotes |
humans |
|
|
|
|
Tax:9606 |
| T81 |
333-339 |
Species |
denotes |
humans |
|
|
|
|
Tax:9606 |
| T82 |
524-543 |
NegativeRegulation |
denotes |
negative regulatory |
|
|
|
|
|
| T83 |
700-707 |
Biological |
denotes |
cardiac |
|
|
|
|
|
| T84 |
709-717 |
Biological |
denotes |
vascular |
|
|
|
|
|
| T85 |
729-737 |
Biological |
denotes |
outcomes |
|
|
|
|
|
| T86 |
722-737 |
Biological |
denotes |
immune outcomes |
|
|
|
|
|
| T87 |
797-811 |
Disease |
denotes |
cytokine storm |
|
|
|
|
http://purl.obolibrary.org/obo/HP_0033041 |
| T88 |
4746-4760 |
Disease |
denotes |
cytokine storm |
|
|
|
|
http://purl.obolibrary.org/obo/HP_0033041 |
| T89 |
460-469 |
Chemical |
denotes |
vitamin D |
|
|
|
|
MESH:D014807 |
| T9 |
5451-5461 |
Species |
denotes |
SARS-CoV-2 |
|
|
|
|
Tax:2697049 |
| T90 |
4981-5001 |
Disease |
denotes |
vitamin D deficiency |
|
|
|
|
http://purl.obolibrary.org/obo/HP_0100512 |
| T91 |
71-76 |
Therapy |
denotes |
Treat |
|
|
|
|
|
| T92 |
589-604 |
PositiveRegulation |
denotes |
over-reactivity |
|
|
|
|
|
| T93 |
571-582 |
NegativeRegulation |
denotes |
dysfunction |
|
|
|
|
|
| T94 |
628-645 |
Disease |
denotes |
hypovitaminosis D |
|
|
|
|
MESH:D014808 |
| T95 |
1930-1947 |
Disease |
denotes |
hypovitaminosis D |
|
|
|
|
MESH:D014808 |
| T96 |
944-979 |
Disease |
denotes |
acute respiratory distress syndrome |
|
|
|
|
MESH:D012128 |
| T97 |
937-943 |
Die |
denotes |
lethal |
|
|
|
|
|
| T98 |
1123-1145 |
Gene |
denotes |
spike (S) glycoprotein |
|
|
|
|
Gene:43740568 |
| T99 |
5425-5447 |
Gene |
denotes |
spike (S) glycoprotein |
|
|
|
|
Gene:43740568 |
| T113 |
1265-1281 |
Biological |
denotes |
epithelial cells |
|
|
|
|
|
| T114 |
1287-1300 |
Biological |
denotes |
blood vessels |
|
|
|
|
|
| T115 |
1302-1306 |
Biological |
denotes |
lung |
|
|
|
|
|
| T116 |
1724-1728 |
Biological |
denotes |
lung |
|
|
|
|
|
| T117 |
1730-1735 |
Biological |
denotes |
heart |
|
|
|
|
|
| T118 |
1347-1352 |
Biological |
denotes |
heart |
|
|
|
|
|
| T119 |
1308-1314 |
Biological |
denotes |
kidney |
|
|
|
|
|
| T120 |
1737-1743 |
Biological |
denotes |
kidney |
|
|
|
|
|
| T121 |
2245-2251 |
Biological |
denotes |
kidney |
|
|
|
|
|
| T122 |
2278-2283 |
Biological |
denotes |
liver |
|
|
|
|
|
| T123 |
1072-1081 |
NegativeRegulation |
denotes |
interfere |
|
|
|
|
|
| T124 |
1332-1341 |
Biological |
denotes |
intestine |
|
|
|
|
|
| T125 |
1368-1384 |
Biological |
denotes |
cerebral neurons |
|
|
|
|
|
| T126 |
1406-1417 |
Biological |
denotes |
macrophages |
|
|
|
|
|
| T127 |
2711-2722 |
Biological |
denotes |
macrophages |
|
|
|
|
|
| T128 |
1389-1395 |
Biological |
denotes |
immune |
|
|
|
|
|
| T131 |
840-846 |
Biological |
denotes |
immune |
|
|
|
|
|
| T133 |
1389-1405 |
Biological |
denotes |
immune monocytes |
|
|
|
|
|
| T134 |
1504-1516 |
Disease |
denotes |
hypertension |
|
|
|
|
MESH:D006973 |
| T135 |
1518-1533 |
Disease |
denotes |
atherosclerosis |
|
|
|
|
MESH:D050197 |
| T136 |
1535-1545 |
Disease |
denotes |
thrombosis |
|
|
|
|
MESH:D013927 |
| T137 |
1547-1559 |
Disease |
denotes |
coagulopathy |
|
|
|
|
MESH:D001778 |
| T138 |
1562-1570 |
Disease |
denotes |
diarrhea |
|
|
|
|
MESH:D003967 |
| T139 |
1572-1580 |
Disease |
denotes |
glaucoma |
|
|
|
|
MESH:D005901 |
| T140 |
1582-1589 |
Disease |
denotes |
anosmia |
|
|
|
|
MESH:D000857 |
| T141 |
1591-1598 |
Disease |
denotes |
ageusia |
|
|
|
|
MESH:D000370 |
| T142 |
1600-1612 |
Disease |
denotes |
skin lesions |
|
|
|
|
MESH:D012871 |
| T143 |
1614-1624 |
Disease |
denotes |
dermatitis |
|
|
|
|
MESH:D003872 |
| T144 |
1627-1680 |
Disease |
denotes |
autoimmune inflammation of the central nervous system |
|
|
|
|
MESH:D020278 |
| T145 |
1686-1693 |
Disease |
denotes |
damages |
|
|
|
|
|
| T146 |
1749-1757 |
Biological |
denotes |
testicle |
|
|
|
|
|
| T147 |
1780-1787 |
Condition |
denotes |
diffuse |
|
|
|
|
|
| T148 |
1831-1844 |
PositiveRegulation |
denotes |
over-reaction |
|
|
|
|
|
| T149 |
1895-1904 |
PositiveRegulation |
denotes |
imbalance |
|
|
|
|
|
| T150 |
2238-2243 |
Gene |
denotes |
Renin |
|
|
|
|
Gene:5972 |
| T151 |
2261-2276 |
Gene |
denotes |
Angiotensinogen |
|
|
|
|
Gene:183 |
| T152 |
2293-2306 |
Gene |
denotes |
Angiotensin I |
peptide |
|
|
|
Gene:183|MESH:D000803 |
| T153 |
2410-2424 |
Gene |
denotes |
Angiotensin II |
peptide |
|
|
|
Gene:183|MESH:D000804 |
| T154 |
2554-2568 |
Gene |
denotes |
Angiotensin II |
peptide |
|
|
|
Gene:183|MESH:D000804 |
| T155 |
2639-2662 |
Gene |
denotes |
Angiotensin II receptor |
|
|
|
|
Gene:185 |
| T156 |
2811-2825 |
Gene |
denotes |
Angiotensin II |
peptide |
|
|
|
Gene:183|MESH:D000804 |
| T157 |
3202-3216 |
Gene |
denotes |
Angiotensin II |
peptide |
|
|
|
Gene:183|MESH:D000804 |
| T158 |
3368-3381 |
Gene |
denotes |
Angiotensin I |
peptide |
|
|
|
Gene:183|MESH:D000803 |
| T159 |
3506-3521 |
Gene |
denotes |
Angiotensin III |
peptide |
|
|
|
Gene:183|MESH:D000805 |
| T160 |
3549-3563 |
Gene |
denotes |
Angiotensin IV |
peptide |
|
|
|
Gene:183|MESH:C496150 |
| T161 |
3730-3745 |
Gene |
denotes |
Angiotensin III |
peptide |
|
|
|
Gene:183|MESH:D000805 |
| T162 |
4031-4045 |
Gene |
denotes |
Angiotensin IV |
peptide |
|
|
|
Gene:183|MESH:C496150 |
| T163 |
5200-5214 |
Gene |
denotes |
Angiotensin II |
peptide |
|
|
|
MESH:D000804|Gene:183 |
| T164 |
5220-5233 |
Gene |
denotes |
Angiotensin I |
peptide |
|
|
|
MESH:D000803|Gene:183 |
| T165 |
5642-5656 |
Gene |
denotes |
Angiotensin IV |
peptide |
|
|
|
MESH:C496150|Gene:183 |
| T166 |
2321-2331 |
Biological |
denotes |
DRVYIHPFHL |
peptide |
|
|
|
|
| T167 |
2439-2447 |
Biological |
denotes |
DRVYIHPF |
peptide |
|
|
|
|
| T169 |
3420-3429 |
Biological |
denotes |
DRVYIHPFH |
peptide |
|
|
|
|
| T170 |
2253-2260 |
Cleave |
denotes |
cleaves |
|
|
|
|
|
| T173 |
2363-2392 |
Gene |
denotes |
Angiotensin-Converting Enzyme |
|
|
|
|
Gene:1636 |
| T174 |
2394-2397 |
Gene |
denotes |
ACE |
|
|
|
|
Gene:1636 |
| T182 |
5155-5169 |
Chemical |
denotes |
ACE inhibitors |
inhibitor|drug |
|
|
|
|
| T184 |
2338-2344 |
Gene |
denotes |
latter |
|
|
|
|
|
| T185 |
2348-2355 |
Cleave |
denotes |
cleaved |
|
|
|
|
|
| T186 |
2794-2801 |
Cleave |
denotes |
cleaved |
|
|
|
|
|
| T189 |
4289-4322 |
Biological |
denotes |
Such naturally-produced molecules |
|
|
|
|
|
| T190 |
2832-2847 |
Gene |
denotes |
Angiotensin 1-7 |
peptide |
|
|
|
Gene:183|MESH:C118790 |
| T191 |
2936-2951 |
Gene |
denotes |
Angiotensin 1-7 |
peptide |
|
|
|
Gene:183|MESH:C118790 |
| T192 |
3172-3187 |
Gene |
denotes |
Angiotensin 1-7 |
peptide |
|
|
|
Gene:183|MESH:C118790 |
| T193 |
3966-3981 |
Gene |
denotes |
Angiotensin 1-7 |
peptide |
|
|
|
Gene:183|MESH:C118790 |
| T194 |
5575-5590 |
Gene |
denotes |
Angiotensin 1-7 |
peptide |
|
|
|
Gene:183|MESH:C118790 |
| T195 |
2862-2869 |
Biological |
denotes |
DRVYIHP |
peptide |
|
|
|
|
| T196 |
2543-2550 |
Bind |
denotes |
targets |
|
|
|
|
|
| T197 |
3438-3445 |
Bind |
denotes |
targets |
|
|
|
|
|
| T198 |
2601-2605 |
Gene |
denotes |
AT1R |
|
|
|
|
Gene:185 |
| T199 |
2665-2669 |
Gene |
denotes |
AT1R |
|
|
|
|
Gene:185 |
| T200 |
3609-3613 |
Gene |
denotes |
AT1R |
|
|
|
|
Gene:185 |
| T201 |
5264-5268 |
Gene |
denotes |
AT1R |
|
|
|
|
Gene:185 |
| T202 |
2633-2637 |
Gene |
denotes |
AT2R |
|
|
|
|
Gene:186 |
| T203 |
3446-3450 |
Gene |
denotes |
AT2R |
|
|
|
|
Gene:186 |
| T204 |
4077-4081 |
Gene |
denotes |
AT2R |
|
|
|
|
Gene:186 |
| T205 |
5729-5733 |
Gene |
denotes |
AT2R |
|
|
|
|
Gene:186 |
| T206 |
3536-3543 |
Biological |
denotes |
RVYIHPF |
peptide |
|
|
|
|
| T209 |
3257-3265 |
Biological |
denotes |
ARVYIHPF |
peptide |
|
|
|
|
| T210 |
3578-3584 |
Biological |
denotes |
VYIHPF |
peptide |
|
|
|
|
| T213 |
3007-3014 |
Biological |
denotes |
ARVYIHP |
peptide |
|
|
|
|
| T214 |
2593-2599 |
Gene |
denotes |
type 1 |
|
|
|
|
Gene:185 |
| T216 |
2639-2662 |
Gene |
denotes |
Angiotensin II receptor |
|
|
|
|
Gene:186 |
| T217 |
2625-2631 |
Gene |
denotes |
type 2 |
|
|
|
|
Gene:186 |
| T218 |
2701-2710 |
Biological |
denotes |
monocytes |
|
|
|
|
|
| T219 |
2727-2734 |
Biological |
denotes |
T-cells |
|
|
|
|
|
| T220 |
2929-2933 |
Gene |
denotes |
MasR |
|
|
|
|
Gene:116511 |
| T221 |
2872-2881 |
Bind |
denotes |
targeting |
|
|
|
|
|
| T222 |
2982-2992 |
Biological |
denotes |
Alamandine |
peptide |
|
|
|
MESH:C581752 |
| T223 |
2967-2978 |
Cleave |
denotes |
transformed |
|
|
|
|
|
| T224 |
3022-3045 |
Biological |
denotes |
aspartate decarboxylase |
|
|
|
|
MESH:C019747 |
| T225 |
3090-3137 |
Gene |
denotes |
Mas-related G protein-coupled receptor member D |
|
|
|
|
Gene:116512 |
| T226 |
3139-3143 |
Gene |
denotes |
MRGD |
|
|
|
|
Gene:116512 |
| T228 |
3047-3057 |
Biological |
denotes |
Alamandine |
peptide |
|
|
|
MESH:C581752 |
| T229 |
3064-3068 |
Bind |
denotes |
bind |
|
|
|
|
|
| T230 |
3229-3242 |
Biological |
denotes |
Angiotensin A |
peptide |
|
|
|
MESH:C516880 |
| T231 |
3221-3228 |
Produce |
denotes |
produce |
|
|
|
|
|
| T232 |
3274-3297 |
Biological |
denotes |
aspartate decarboxylase |
|
|
|
|
MESH:C019747 |
| T233 |
3337-3345 |
Cleave |
denotes |
cleavage |
|
|
|
|
|
| T234 |
3303-3313 |
Biological |
denotes |
Alamandine |
peptide |
|
|
|
MESH:C581752 |
| T235 |
3390-3405 |
Gene |
denotes |
Angiotensin 1-9 |
peptide |
|
|
|
Gene:183|MESH:C506331 |
| T236 |
3361-3367 |
Cleave |
denotes |
cleave |
|
|
|
|
|
| T237 |
3595-3604 |
Bind |
denotes |
targeting |
|
|
|
|
|
| T238 |
3632-3636 |
Biological |
denotes |
AT4R |
|
|
|
May be MESH:C090830? |
|
| T239 |
3595-3604 |
Bind |
denotes |
targeting |
|
|
|
|
|
| T241 |
3714-3715 |
Gene |
denotes |
I |
peptide |
|
|
|
MESH:D000803|Gene:183 |
| T243 |
3701-3712 |
Gene |
denotes |
Angiotensin |
peptide |
|
|
|
MESH:D000803|Gene:183 |
| T245 |
3720-3722 |
Gene |
denotes |
II |
peptide |
|
|
|
MESH:D000804|Gene:183 |
| T247 |
3701-3712 |
Gene |
denotes |
Angiotensin |
peptide |
|
|
|
MESH:D000804|Gene:183 |
| T248 |
3983-3998 |
Gene |
denotes |
Angiotensin 1-9 |
peptide |
|
|
|
Gene:183|MESH:C506331 |
| T249 |
5592-5607 |
Gene |
denotes |
Angiotensin 1-9 |
peptide |
|
|
|
Gene:183|MESH:C506331 |
| T250 |
5609-5619 |
Biological |
denotes |
Alamandine |
peptide |
|
|
|
MESH:C581752 |
| T251 |
4000-4010 |
Biological |
denotes |
Alamandine |
peptide |
|
|
|
MESH:C581752 |
| T252 |
4012-4025 |
Biological |
denotes |
Angiotensin A |
peptide |
|
|
|
MESH:C516880 |
| T253 |
5621-5634 |
Biological |
denotes |
Angiotensin A |
peptide |
|
|
|
MESH:C516880 |
| T254 |
4057-4066 |
Bind |
denotes |
targeting |
|
|
|
|
|
| T255 |
4071-4075 |
Gene |
denotes |
MasR |
|
|
|
|
Gene:116511 |
| T256 |
4083-4087 |
Gene |
denotes |
MRGD |
|
|
|
|
Gene:116512 |
| T257 |
4098-4102 |
Biological |
denotes |
AT4R |
|
May be MESH:C090830? |
|
|
|
| T258 |
4057-4066 |
Bind |
denotes |
targeting |
|
|
|
|
|
| T259 |
4057-4066 |
Bind |
denotes |
targeting |
|
|
|
|
|
| T260 |
4057-4066 |
Bind |
denotes |
targeting |
|
|
|
|
|
| T261 |
4057-4066 |
Bind |
denotes |
targeting |
|
|
|
|
|
| T262 |
3940-3951 |
Biological |
denotes |
homeostasis |
|
|
|
|
|
| T263 |
4142-4156 |
Biological |
denotes |
These peptides |
|
|
|
|
|
| T264 |
4179-4195 |
Biological |
denotes |
cardioprotective |
|
|
|
|
|
| T265 |
4197-4207 |
Biological |
denotes |
vasoactive |
|
|
|
|
|
| T266 |
4209-4226 |
Biological |
denotes |
anti-hypertensive |
|
|
|
|
|
| T267 |
4229-4246 |
Biological |
denotes |
anti-hypertrophic |
|
|
|
|
|
| T268 |
4254-4271 |
Biological |
denotes |
anti-inflammatory |
|
|
|
|
|
| T269 |
4350-4360 |
NegativeRegulation |
denotes |
counteract |
|
|
|
|
|
| T270 |
4384-4399 |
PositiveRegulation |
denotes |
over-activation |
|
|
|
|
|
| T271 |
4411-4418 |
BecomeReduce |
denotes |
reverse |
|
|
|
|
|
| T272 |
4734-4741 |
Chemical |
denotes |
prevent |
|
|
|
|
|
| T273 |
4806-4832 |
Biological |
denotes |
pro-inflammatory cytokines |
|
|
|
|
|
| T274 |
4795-4802 |
Release |
denotes |
release |
|
|
|
|
|
| T275 |
4783-4790 |
NegativeRegulation |
denotes |
control |
|
|
|
|
|
| T276 |
4924-4936 |
PositiveRegulation |
denotes |
over-reacted |
|
|
|
|
|
| T277 |
4961-4966 |
Species |
denotes |
viral |
|
|
|
|
|
| T279 |
4967-4976 |
Disease |
denotes |
infection |
|
|
|
|
MESH:D007239 |
| T280 |
5076-5117 |
Chemical |
denotes |
specific candidate chemotherapeutic drugs |
drug |
|
|
|
|
| T281 |
5186-5196 |
Cleave |
denotes |
production |
|
|
|
|
|
| T282 |
5174-5181 |
NegativeRegulation |
denotes |
prevent |
|
|
|
|
|
| T283 |
5240-5248 |
Chemical |
denotes |
blockers |
inhibitor|drug |
|
|
|
|
| T284 |
5249-5260 |
Chemical |
denotes |
antagonists |
inhibitor|drug |
|
|
|
|
| T285 |
5277-5285 |
Chemical |
denotes |
Losartan |
inhibitor|drug |
|
|
|
|
| T286 |
5277-5285 |
Chemical |
denotes |
Losartan |
inhibitor|drug |
|
|
|
|
| T288 |
5290-5301 |
Chemical |
denotes |
derivatives |
inhibitor|drug |
|
|
|
|
| T289 |
5123-5141 |
Chemical |
denotes |
proposed molecules |
|
|
|
|
|
| T290 |
5303-5314 |
Recombinant |
denotes |
Recombinant |
|
|
|
|
|
| T291 |
5410-5417 |
Bind |
denotes |
binding |
|
|
|
|
|
| T292 |
5398-5409 |
NegativeRegulation |
denotes |
competitive |
|
|
|
|
|
| T293 |
5501-5524 |
Chemical |
denotes |
candidate peptide drugs |
drug |
|
|
|
|
| T294 |
5723-5727 |
Gene |
denotes |
MasR |
|
|
|
|
Gene:116511 |
| T295 |
5735-5739 |
Gene |
denotes |
MRGD |
|
|
|
|
Gene:116512 |
| T296 |
5750-5754 |
Biological |
denotes |
AT4R |
|
May be MESH:C090830? |
|
|
|
| T297 |
5690-5698 |
Bind |
denotes |
targeted |
|
|
|
|
|
| T298 |
5690-5698 |
Bind |
denotes |
targeted |
|
|
|
|
|
| T299 |
5690-5698 |
Bind |
denotes |
targeted |
|
|
|
|
|
| T300 |
5690-5698 |
Bind |
denotes |
targeted |
|
|
|
|
|
| T301 |
5690-5698 |
Bind |
denotes |
targeted |
|
|
|
|
|
| R1 |
T25 |
T26 |
for |
'Renin-Angiotensin' System,Candidate Drugs |
| R10 |
T67 |
T66 |
of_a |
renal,functions |
| R11 |
T70 |
T66 |
of_a |
cardiovascular,functions |
| R12 |
T71 |
T66 |
of_a |
innate immune,functions |
| R105 |
T185 |
T153 |
into |
cleaved,Angiotensin II |
| R106 |
T185 |
T167 |
into |
cleaved,DRVYIHPF |
| R107 |
T173 |
T185 |
using |
Angiotensin-Converting Enzyme,cleaved |
| R108 |
T156 |
T186 |
is_a |
Angiotensin II,cleaved |
| R109 |
T186 |
T190 |
into |
cleaved,Angiotensin 1-7 |
| R110 |
T103 |
T186 |
using |
ACE2,cleaved |
| R111 |
T186 |
T195 |
into |
cleaved,DRVYIHP |
| R28 |
T89 |
T82 |
is_a |
vitamin D,negative regulatory |
| R29 |
T82 |
T38 |
is_a |
negative regulatory,RAS |
| R63 |
T125 |
T111 |
on |
cerebral neurons,expressed |
| R64 |
T133 |
T111 |
on |
immune monocytes,expressed |
| R65 |
T128 |
T111 |
on |
immune,expressed |
| R13 |
T12 |
T32 |
has_a |
COVID-19,patients |
| R14 |
T5 |
T29 |
cause_of |
SARS-CoV-2,infected |
| R15 |
T29 |
T30 |
has_a |
infected,persons |
| R16 |
T64 |
T45 |
is_a |
Counter-regulatory,RAS |
| R17 |
T78 |
T52 |
is_a |
'counter-regulatory',RAS |
| R18 |
T20 |
T33 |
has_a |
COVID-19,patients |
| R19 |
T8 |
T27 |
cause_of |
SARS-CoV-2,infected |
| R2 |
T28 |
T31 |
has_a |
infected,patients |
| R20 |
T27 |
T80 |
has_a |
infected,humans |
| R21 |
T79 |
T61 |
is_a |
'counter-regulatory',RAS |
| R22 |
T68 |
T85 |
of_a |
renal,outcomes |
| R23 |
T83 |
T85 |
of_a |
cardiac,outcomes |
| R24 |
T84 |
T85 |
of_a |
vascular,outcomes |
| R25 |
T26 |
T91 |
using |
Candidate Drugs,Treat |
| R26 |
T10 |
T91 |
for |
COVID-19,Treat |
| R27 |
T10 |
T31 |
has_a |
COVID-19,patients |
| R3 |
T1 |
T28 |
cause_of |
SARS-CoV-2,infected |
| R30 |
T93 |
T39 |
is_a |
dysfunction,RAS |
| R31 |
T92 |
T39 |
is_a |
over-reactivity,RAS |
| R32 |
T39 |
T86 |
cause_of |
RAS,immune outcomes |
| R33 |
T39 |
T85 |
cause_of |
RAS,outcomes |
| R34 |
T94 |
T86 |
cause_of |
hypovitaminosis D,immune outcomes |
| R35 |
T94 |
T85 |
cause_of |
hypovitaminosis D,outcomes |
| R36 |
T86 |
T32 |
has_a |
immune outcomes,patients |
| R37 |
T85 |
T32 |
has_a |
outcomes,patients |
| R4 |
T36 |
T35 |
abbreviation |
RAS,'Renin-Angiotensin' System |
| R41 |
T96 |
T97 |
has_status |
acute respiratory distress syndrome,lethal |
| R42 |
T94 |
T87 |
cause_of |
hypovitaminosis D,cytokine storm |
| R43 |
T94 |
T96 |
cause_of |
hypovitaminosis D,acute respiratory distress syndrome |
| R44 |
T39 |
T87 |
cause_of |
RAS,cytokine storm |
| R45 |
T39 |
T96 |
cause_of |
RAS,acute respiratory distress syndrome |
| R46 |
T96 |
T32 |
has_a |
acute respiratory distress syndrome,patients |
| R47 |
T87 |
T32 |
has_a |
cytokine storm,patients |
| R48 |
T101 |
T110 |
abbreviation |
ACE2,Angiotensin-Converting Enzyme 2 |
| R5 |
T37 |
T62 |
abbreviation |
RAS,'Renin-Angiotensin' system |
| R6 |
T63 |
T25 |
is_a |
Counter-regulatory,'Renin-Angiotensin' System |
| R7 |
T65 |
T62 |
synonym |
'Renin-Angiotensin-Aldosterone' system,'Renin-Angiotensin' system |
| R8 |
T62 |
T72 |
is_a |
'Renin-Angiotensin' system,regulator |
| R9 |
T72 |
T66 |
is_a |
regulator,functions |
| R49 |
T3 |
T13 |
cause_of |
SARS-CoV-2,COVID-19 |
| R50 |
T3 |
T100 |
is_a |
SARS-CoV-2,interacting |
| R51 |
T100 |
T110 |
with |
interacting,Angiotensin-Converting Enzyme 2 |
| R52 |
T98 |
T100 |
via |
spike (S) glycoprotein,interacting |
| R53 |
T100 |
T123 |
is_a |
interacting,interfere |
| R54 |
T123 |
T40 |
is_a |
interfere,RAS |
| R55 |
T128 |
T126 |
- |
immune,macrophages |
| R56 |
T114 |
T113 |
of_a |
blood vessels,epithelial cells |
| R57 |
T115 |
T113 |
of_a |
lung,epithelial cells |
| R58 |
T119 |
T113 |
of_a |
kidney,epithelial cells |
| R59 |
T69 |
T113 |
of_a |
renal tubules,epithelial cells |
| R60 |
T124 |
T113 |
of_a |
intestine,epithelial cells |
| R61 |
T118 |
T113 |
of_a |
heart,epithelial cells |
| R62 |
T113 |
T111 |
on |
epithelial cells,expressed |
| R66 |
T4 |
T14 |
cause_of |
SARS-CoV-2,COVID-19 |
| R67 |
T134 |
T14 |
is_a |
hypertension,COVID-19 |
| R68 |
T135 |
T14 |
is_a |
atherosclerosis,COVID-19 |
| R69 |
T136 |
T14 |
is_a |
thrombosis,COVID-19 |
| R70 |
T137 |
T14 |
is_a |
coagulopathy,COVID-19 |
| R71 |
T138 |
T14 |
is_a |
diarrhea,COVID-19 |
| R72 |
T139 |
T14 |
is_a |
glaucoma,COVID-19 |
| R73 |
T140 |
T14 |
is_a |
anosmia,COVID-19 |
| R74 |
T141 |
T14 |
is_a |
ageusia,COVID-19 |
| R75 |
T142 |
T14 |
is_a |
skin lesions,COVID-19 |
| R76 |
T143 |
T14 |
is_a |
dermatitis,COVID-19 |
| R77 |
T144 |
T14 |
is_a |
autoimmune inflammation of the central nervous system,COVID-19 |
| R78 |
T145 |
T14 |
is_a |
damages,COVID-19 |
| R79 |
T116 |
T145 |
to |
lung,damages |
| R80 |
T117 |
T145 |
to |
heart,damages |
| R81 |
T120 |
T145 |
to |
kidney,damages |
| R82 |
T146 |
T145 |
to |
testicle,damages |
| R83 |
T148 |
T41 |
is_a |
over-reaction,RAS |
| R84 |
T148 |
T15 |
cause_of |
over-reaction,COVID-19 |
| R85 |
T15 |
T147 |
has_status |
COVID-19,diffuse |
| R86 |
T30 |
T41 |
in |
persons,RAS |
| R87 |
T149 |
T42 |
is_a |
imbalance,RAS |
| R88 |
T149 |
T95 |
cause_of |
imbalance,hypovitaminosis D |
| R89 |
T149 |
T148 |
coreference |
imbalance,over-reaction |
| R90 |
T121 |
T150 |
in |
kidney,Renin |
| R91 |
T122 |
T151 |
in |
liver,Angiotensinogen |
| R92 |
T150 |
T170 |
using |
Renin,cleaves |
| R97 |
T174 |
T173 |
abbreviation |
ACE,Angiotensin-Converting Enzyme |
| R100 |
T184 |
T152 |
coreference |
latter,Angiotensin I |
| R101 |
T184 |
T185 |
is_a |
latter,cleaved |
| R102 |
T151 |
T170 |
is_a |
Angiotensinogen,cleaves |
| R103 |
T170 |
T152 |
into |
cleaves,Angiotensin I |
| R104 |
T170 |
T166 |
into |
cleaves,DRVYIHPFHL |
| R112 |
T214 |
T155 |
- |
type 1,Angiotensin II receptor |
| R113 |
T217 |
T216 |
- |
type 2,Angiotensin II receptor |
| R114 |
T154 |
T196 |
is_a |
Angiotensin II,targets |
| R115 |
T196 |
T214 |
to |
targets,type 1 |
| R116 |
T196 |
T217 |
to |
targets,type 2 |
| R117 |
T198 |
T214 |
abbreviation |
AT1R,type 1 |
| R118 |
T202 |
T217 |
abbreviation |
AT2R,type 2 |
| R119 |
T199 |
T112 |
is_a |
AT1R,expressed |
| R120 |
T218 |
T112 |
on |
monocytes,expressed |
| R121 |
T127 |
T112 |
on |
macrophages,expressed |
| R122 |
T219 |
T112 |
on |
T-cells,expressed |
| R123 |
T190 |
T221 |
is_a |
Angiotensin 1-7,targeting |
| R124 |
T221 |
T220 |
to |
targeting,MasR |
| R125 |
T191 |
T223 |
is_a |
Angiotensin 1-7,transformed |
| R126 |
T223 |
T222 |
into |
transformed,Alamandine |
| R127 |
T223 |
T213 |
into |
transformed,ARVYIHP |
| R128 |
T224 |
T223 |
using |
aspartate decarboxylase,transformed |
| R129 |
T226 |
T225 |
abbreviation |
MRGD,Mas-related G protein-coupled receptor member D |
| R130 |
T228 |
T229 |
is_a |
Alamandine,bind |
| R131 |
T229 |
T225 |
to |
bind,Mas-related G protein-coupled receptor member D |
| R132 |
T157 |
T231 |
is_a |
Angiotensin II,produce |
| R133 |
T231 |
T230 |
is_a |
produce,Angiotensin A |
| R134 |
T231 |
T209 |
is_a |
produce,ARVYIHPF |
| R135 |
T232 |
T231 |
using |
aspartate decarboxylase,produce |
| R136 |
T230 |
T233 |
is_a |
Angiotensin A,cleavage |
| R137 |
T233 |
T234 |
into |
cleavage,Alamandine |
| R138 |
T104 |
T234 |
using |
ACE2,Alamandine |
| R139 |
T158 |
T236 |
is_a |
Angiotensin I,cleave |
| R140 |
T236 |
T235 |
into |
cleave,Angiotensin 1-9 |
| R141 |
T105 |
T236 |
using |
ACE2,cleave |
| R142 |
T236 |
T169 |
into |
cleave,DRVYIHPFH |
| R143 |
T235 |
T197 |
is_a |
Angiotensin 1-9,targets |
| R145 |
T159 |
T237 |
is_a |
Angiotensin III,targeting |
| R146 |
T206 |
T237 |
is_a |
RVYIHPF,targeting |
| R147 |
T237 |
T200 |
to |
targeting,AT1R |
| R148 |
T160 |
T239 |
is_a |
Angiotensin IV,targeting |
| R149 |
T210 |
T239 |
is_a |
VYIHPF,targeting |
| R150 |
T239 |
T238 |
to |
targeting,AT4R |
| R151 |
T243 |
T241 |
- |
Angiotensin,I |
| R152 |
T247 |
T245 |
- |
Angiotensin,II |
| R153 |
T193 |
T254 |
is_a |
Angiotensin 1-7,targeting |
| R154 |
T254 |
T255 |
to |
targeting,MasR |
| R155 |
T197 |
T203 |
to |
targets,AT2R |
| R156 |
T248 |
T258 |
is_a |
Angiotensin 1-9,targeting |
| R157 |
T258 |
T204 |
to |
targeting,AT2R |
| R158 |
T251 |
T259 |
is_a |
Alamandine,targeting |
| R159 |
T259 |
T256 |
to |
targeting,MRGD |
| R160 |
T252 |
T260 |
is_a |
Angiotensin A,targeting |
| R161 |
T260 |
T106 |
to |
targeting,ACE2 |
| R162 |
T162 |
T261 |
is_a |
Angiotensin IV,targeting |
| R163 |
T261 |
T257 |
to |
targeting,AT4R |
| R164 |
T263 |
T193 |
coreference |
These peptides,Angiotensin 1-7 |
| R165 |
T263 |
T248 |
coreference |
These peptides,Angiotensin 1-9 |
| R166 |
T263 |
T251 |
coreference |
These peptides,Alamandine |
| R167 |
T263 |
T252 |
coreference |
These peptides,Angiotensin A |
| R168 |
T263 |
T162 |
coreference |
These peptides,Angiotensin IV |
| R169 |
T263 |
T264 |
cause_of |
These peptides,cardioprotective |
| R170 |
T263 |
T265 |
cause_of |
These peptides,vasoactive |
| R171 |
T263 |
T266 |
cause_of |
These peptides,anti-hypertensive |
| R172 |
T263 |
T267 |
cause_of |
These peptides,anti-hypertrophic |
| R173 |
T263 |
T268 |
cause_of |
These peptides,anti-inflammatory |
| R174 |
T271 |
T19 |
is_a |
reverse,COVID-19 |
| R175 |
T189 |
T263 |
coreference |
Such naturally-produced molecules,These peptides |
| R176 |
T189 |
T269 |
is_a |
Such naturally-produced molecules,counteract |
| R177 |
T269 |
T270 |
is_a |
counteract,over-activation |
| R178 |
T270 |
T54 |
is_a |
over-activation,RAS |
| R179 |
T53 |
T189 |
of_a |
RAS,Such naturally-produced molecules |
| R180 |
T189 |
T271 |
is_a |
Such naturally-produced molecules,reverse |
| R181 |
T7 |
T270 |
cause_of |
SARS-CoV-2,over-activation |
| R182 |
T57 |
T275 |
is_a |
RAS inhibitors,control |
| R183 |
T275 |
T274 |
is_a |
control,release |
| R184 |
T274 |
T273 |
is_a |
release,pro-inflammatory cytokines |
| R185 |
T274 |
T88 |
cause_of |
release,cytokine storm |
| R186 |
T277 |
T279 |
of_a |
viral,infection |
| R187 |
T277 |
T8 |
coreference |
viral,SARS-CoV-2 |
| R188 |
T279 |
T276 |
is_a |
infection,over-reacted |
| R189 |
T90 |
T276 |
is_a |
vitamin D deficiency,over-reacted |
| R190 |
T276 |
T59 |
is_a |
over-reacted,RAS |
| R191 |
T276 |
T22 |
cause_of |
over-reacted,COVID-19 |
| R192 |
T107 |
T279 |
via |
ACE2,infection |
| R193 |
T164 |
T281 |
is_a |
Angiotensin I,production |
| R194 |
T281 |
T163 |
to |
production,Angiotensin II |
| R195 |
T282 |
T281 |
is_a |
prevent,production |
| R196 |
T182 |
T282 |
is_a |
ACE inhibitors,prevent |
| R197 |
T286 |
T288 |
- |
Losartan,derivatives |
| R198 |
T289 |
T280 |
coreference |
proposed molecules,specific candidate chemotherapeutic drugs |
| R199 |
T182 |
T289 |
is_a |
ACE inhibitors,proposed molecules |
| R200 |
T285 |
T289 |
is_a |
Losartan,proposed molecules |
| R201 |
T286 |
T289 |
is_a |
Losartan,proposed molecules |
| R202 |
T201 |
T284 |
of_a |
AT1R,antagonists |
| R203 |
T201 |
T283 |
of_a |
AT1R,blockers |
| R204 |
T283 |
T289 |
is_a |
blockers,proposed molecules |
| R205 |
T284 |
T289 |
is_a |
antagonists,proposed molecules |
| R206 |
T290 |
T108 |
is_a |
Recombinant,ACE2 |
| R207 |
T108 |
T292 |
is_a |
ACE2,competitive |
| R208 |
T292 |
T291 |
is_a |
competitive,binding |
| R209 |
T291 |
T99 |
to |
binding,spike (S) glycoprotein |
| R210 |
T9 |
T99 |
of_a |
SARS-CoV-2,spike (S) glycoprotein |
| R211 |
T194 |
T293 |
is_a |
Angiotensin 1-7,candidate peptide drugs |
| R212 |
T249 |
T293 |
is_a |
Angiotensin 1-9,candidate peptide drugs |
| R213 |
T250 |
T293 |
is_a |
Alamandine,candidate peptide drugs |
| R214 |
T253 |
T293 |
is_a |
Angiotensin A,candidate peptide drugs |
| R215 |
T165 |
T293 |
is_a |
Angiotensin IV,candidate peptide drugs |
| R216 |
T24 |
T293 |
for |
COVID-19,candidate peptide drugs |
| R217 |
T194 |
T297 |
is_a |
Angiotensin 1-7,targeted |
| R218 |
T297 |
T294 |
to |
targeted,MasR |
| R219 |
T249 |
T298 |
is_a |
Angiotensin 1-9,targeted |
| R220 |
T298 |
T205 |
to |
targeted,AT2R |
| R221 |
T250 |
T299 |
is_a |
Alamandine,targeted |
| R222 |
T299 |
T295 |
to |
targeted,MRGD |
| R223 |
T253 |
T300 |
is_a |
Angiotensin A,targeted |
| R224 |
T300 |
T109 |
to |
targeted,ACE2 |
| R225 |
T301 |
T296 |
to |
targeted,AT4R |
| R226 |
T165 |
T301 |
is_a |
Angiotensin IV,targeted |