Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-134 |
Sentence |
denotes |
Fucosyltransferase activities in human pancreatic tissue: comparative study between cancer tissues and established tumoral cell lines. |
T1 |
0-134 |
Sentence |
denotes |
Fucosyltransferase activities in human pancreatic tissue: comparative study between cancer tissues and established tumoral cell lines. |
T1 |
0-134 |
Sentence |
denotes |
Fucosyltransferase activities in human pancreatic tissue: comparative study between cancer tissues and established tumoral cell lines. |
TextSentencer_T2 |
135-297 |
Sentence |
denotes |
Human pancreatic cancer is characterized by an alteration in fucose-containing surface blood group antigens such as H antigen, Lewis b, Lewis y, and sialyl-Lewis. |
T2 |
135-297 |
Sentence |
denotes |
Human pancreatic cancer is characterized by an alteration in fucose-containing surface blood group antigens such as H antigen, Lewis b, Lewis y, and sialyl-Lewis. |
T2 |
135-520 |
Sentence |
denotes |
Human pancreatic cancer is characterized by an alteration in fucose-containing surface blood group antigens such as H antigen, Lewis b, Lewis y, and sialyl-Lewis. These carbohydrate determinants can be synthesized by sequential action of alpha(2,3) sialyltransferases or alpha(1,2) fucosyltransferases (Fuc-T) and alpha(1,3/1,4) fucosyltransferases on (poly)N-acetyllactosamine chains. |
TextSentencer_T3 |
298-520 |
Sentence |
denotes |
These carbohydrate determinants can be synthesized by sequential action of alpha(2,3) sialyltransferases or alpha(1,2) fucosyltransferases (Fuc-T) and alpha(1,3/1,4) fucosyltransferases on (poly)N-acetyllactosamine chains. |
T3 |
298-520 |
Sentence |
denotes |
These carbohydrate determinants can be synthesized by sequential action of alpha(2,3) sialyltransferases or alpha(1,2) fucosyltransferases (Fuc-T) and alpha(1,3/1,4) fucosyltransferases on (poly)N-acetyllactosamine chains. |
TextSentencer_T4 |
521-695 |
Sentence |
denotes |
Therefore, the expression and the function of seven fucosyltransferases were investigated in normal and cancer pancreatic tissues and in four pancreatic carcinoma cell lines. |
T3 |
521-695 |
Sentence |
denotes |
Therefore, the expression and the function of seven fucosyltransferases were investigated in normal and cancer pancreatic tissues and in four pancreatic carcinoma cell lines. |
T4 |
521-695 |
Sentence |
denotes |
Therefore, the expression and the function of seven fucosyltransferases were investigated in normal and cancer pancreatic tissues and in four pancreatic carcinoma cell lines. |
TextSentencer_T5 |
696-839 |
Sentence |
denotes |
Transcripts of FUT1, FUT2, FUT3, FUT4, FUT5, and FUT7 were detected by RT-PCR in carcinoma cell lines as well as in normal and tumoral tissues. |
T4 |
696-839 |
Sentence |
denotes |
Transcripts of FUT1, FUT2, FUT3, FUT4, FUT5, and FUT7 were detected by RT-PCR in carcinoma cell lines as well as in normal and tumoral tissues. |
T5 |
696-839 |
Sentence |
denotes |
Transcripts of FUT1, FUT2, FUT3, FUT4, FUT5, and FUT7 were detected by RT-PCR in carcinoma cell lines as well as in normal and tumoral tissues. |
TextSentencer_T6 |
840-909 |
Sentence |
denotes |
Interestingly, the FUT6 message was only detected in tumoral tissues. |
T5 |
840-909 |
Sentence |
denotes |
Interestingly, the FUT6 message was only detected in tumoral tissues. |
T6 |
840-909 |
Sentence |
denotes |
Interestingly, the FUT6 message was only detected in tumoral tissues. |
TextSentencer_T7 |
910-1270 |
Sentence |
denotes |
Analysis of the acceptor substrate specificity for fucosyltransferases indicated that alpha(1,2) Fuc-T, alpha(1,3) Fuc-T, and alpha(1,4) Fuc-T were expressed in microsome preparations of all tissues as demonstrated by fucose incorporation into phenyl beta-d-galactoside, 2'-fucosyllactose, N-acetyllactosamine, 3'-sialyl-N-acetyllactosamine, and lacto-N-biose. |
T6 |
910-1270 |
Sentence |
denotes |
Analysis of the acceptor substrate specificity for fucosyltransferases indicated that alpha(1,2) Fuc-T, alpha(1,3) Fuc-T, and alpha(1,4) Fuc-T were expressed in microsome preparations of all tissues as demonstrated by fucose incorporation into phenyl beta-d-galactoside, 2'-fucosyllactose, N-acetyllactosamine, 3'-sialyl-N-acetyllactosamine, and lacto-N-biose. |
T7 |
910-1270 |
Sentence |
denotes |
Analysis of the acceptor substrate specificity for fucosyltransferases indicated that alpha(1,2) Fuc-T, alpha(1,3) Fuc-T, and alpha(1,4) Fuc-T were expressed in microsome preparations of all tissues as demonstrated by fucose incorporation into phenyl beta-d-galactoside, 2'-fucosyllactose, N-acetyllactosamine, 3'-sialyl-N-acetyllactosamine, and lacto-N-biose. |
TextSentencer_T8 |
1271-1339 |
Sentence |
denotes |
However, these fucosyltransferase activities varied between tissues. |
T7 |
1271-1339 |
Sentence |
denotes |
However, these fucosyltransferase activities varied between tissues. |
T8 |
1271-1339 |
Sentence |
denotes |
However, these fucosyltransferase activities varied between tissues. |
TextSentencer_T9 |
1340-1466 |
Sentence |
denotes |
A substantial decrease of alpha(1,2) Fuc-T activity was observed in tumoral tissues and cell lines compared to normal tissues. |
T8 |
1340-1466 |
Sentence |
denotes |
A substantial decrease of alpha(1,2) Fuc-T activity was observed in tumoral tissues and cell lines compared to normal tissues. |
T9 |
1340-1466 |
Sentence |
denotes |
A substantial decrease of alpha(1,2) Fuc-T activity was observed in tumoral tissues and cell lines compared to normal tissues. |
TextSentencer_T10 |
1467-1699 |
Sentence |
denotes |
Conversely, the activity of alpha(1,4) Fuc-T, which generates Lewis a and sialyl-Lewis a structures, and that of alpha(1,3) Fuc-T, able to generate a lactodifucotetraose structure, were very important in SOJ-6 and BxPC-3 cell lines. |
T9 |
1467-1699 |
Sentence |
denotes |
Conversely, the activity of alpha(1,4) Fuc-T, which generates Lewis a and sialyl-Lewis a structures, and that of alpha(1,3) Fuc-T, able to generate a lactodifucotetraose structure, were very important in SOJ-6 and BxPC-3 cell lines. |
T10 |
1467-1699 |
Sentence |
denotes |
Conversely, the activity of alpha(1,4) Fuc-T, which generates Lewis a and sialyl-Lewis a structures, and that of alpha(1,3) Fuc-T, able to generate a lactodifucotetraose structure, were very important in SOJ-6 and BxPC-3 cell lines. |
TextSentencer_T11 |
1700-1815 |
Sentence |
denotes |
These increases correlated with an enhanced expression of Lewis a, sialyl-Lewis a, and Lewis y on the cell surface. |
T10 |
1700-1815 |
Sentence |
denotes |
These increases correlated with an enhanced expression of Lewis a, sialyl-Lewis a, and Lewis y on the cell surface. |
T11 |
1700-1815 |
Sentence |
denotes |
These increases correlated with an enhanced expression of Lewis a, sialyl-Lewis a, and Lewis y on the cell surface. |
TextSentencer_T12 |
1816-1991 |
Sentence |
denotes |
The activity of alpha(1,3) Fuc-T, which participates in the synthesis of the sialyl-Lewis x structure, was not significantly modified in cell lines compared to normal tissues. |
T11 |
1816-1991 |
Sentence |
denotes |
The activity of alpha(1,3) Fuc-T, which participates in the synthesis of the sialyl-Lewis x structure, was not significantly modified in cell lines compared to normal tissues. |
T12 |
1816-1991 |
Sentence |
denotes |
The activity of alpha(1,3) Fuc-T, which participates in the synthesis of the sialyl-Lewis x structure, was not significantly modified in cell lines compared to normal tissues. |
TextSentencer_T13 |
1992-2246 |
Sentence |
denotes |
However, the sialyl-Lewis x antigen was expressed preferentially on the surface of SOJ-6 and BxPC-3 cell lines but was not detected on Panc-1 and MiaPaca-2 cell lines suggesting that several alpha(1,3) Fuc-T might be involved in sialyl-Lewis x synthesis. |
T12 |
1992-2246 |
Sentence |
denotes |
However, the sialyl-Lewis x antigen was expressed preferentially on the surface of SOJ-6 and BxPC-3 cell lines but was not detected on Panc-1 and MiaPaca-2 cell lines suggesting that several alpha(1,3) Fuc-T might be involved in sialyl-Lewis x synthesis. |
T13 |
1992-2246 |
Sentence |
denotes |
However, the sialyl-Lewis x antigen was expressed preferentially on the surface of SOJ-6 and BxPC-3 cell lines but was not detected on Panc-1 and MiaPaca-2 cell lines suggesting that several alpha(1,3) Fuc-T might be involved in sialyl-Lewis x synthesis. |