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PubMed:26175457 JSONTXT 45 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-85 Sentence denotes The multiple roles of epidermal growth factor repeat O-glycans in animal development.
T1 0-85 Sentence denotes The multiple roles of epidermal growth factor repeat O-glycans in animal development.
T1 0-85 Sentence denotes The multiple roles of epidermal growth factor repeat O-glycans in animal development.
TextSentencer_T2 86-258 Sentence denotes The epidermal growth factor (EGF)-like repeat is a common, evolutionarily conserved motif found in secreted proteins and the extracellular domain of transmembrane proteins.
T2 86-258 Sentence denotes The epidermal growth factor (EGF)-like repeat is a common, evolutionarily conserved motif found in secreted proteins and the extracellular domain of transmembrane proteins.
T2 86-258 Sentence denotes The epidermal growth factor (EGF)-like repeat is a common, evolutionarily conserved motif found in secreted proteins and the extracellular domain of transmembrane proteins.
TextSentencer_T3 259-401 Sentence denotes EGF repeats harbor six cysteine residues which form three disulfide bonds and help generate the three-dimensional structure of the EGF repeat.
T3 259-401 Sentence denotes EGF repeats harbor six cysteine residues which form three disulfide bonds and help generate the three-dimensional structure of the EGF repeat.
T3 259-401 Sentence denotes EGF repeats harbor six cysteine residues which form three disulfide bonds and help generate the three-dimensional structure of the EGF repeat.
TextSentencer_T4 402-573 Sentence denotes A subset of EGF repeats harbor consensus sequences for the addition of one or more specific O-glycans, which are initiated by O-glucose, O-fucose or O-N-acetylglucosamine.
T4 402-573 Sentence denotes A subset of EGF repeats harbor consensus sequences for the addition of one or more specific O-glycans, which are initiated by O-glucose, O-fucose or O-N-acetylglucosamine.
T4 402-573 Sentence denotes A subset of EGF repeats harbor consensus sequences for the addition of one or more specific O-glycans, which are initiated by O-glucose, O-fucose or O-N-acetylglucosamine.
TextSentencer_T5 574-641 Sentence denotes These glycans are relatively rare compared to mucin-type O-glycans.
T5 574-641 Sentence denotes These glycans are relatively rare compared to mucin-type O-glycans.
T5 574-641 Sentence denotes These glycans are relatively rare compared to mucin-type O-glycans.
TextSentencer_T6 642-864 Sentence denotes However, genetic experiments in model organisms and cell-based assays indicate that at least some of the glycosyltransferases involved in the addition of O-glycans to EGF repeats play important roles in animal development.
T6 642-864 Sentence denotes However, genetic experiments in model organisms and cell-based assays indicate that at least some of the glycosyltransferases involved in the addition of O-glycans to EGF repeats play important roles in animal development.
T6 642-864 Sentence denotes However, genetic experiments in model organisms and cell-based assays indicate that at least some of the glycosyltransferases involved in the addition of O-glycans to EGF repeats play important roles in animal development.
TextSentencer_T7 865-1086 Sentence denotes These studies, combined with state-of-the-art biochemical and structural biology experiments have started to provide an in-depth picture of how these glycans regulate the function of the proteins to which they are linked.
T7 865-1086 Sentence denotes These studies, combined with state-of-the-art biochemical and structural biology experiments have started to provide an in-depth picture of how these glycans regulate the function of the proteins to which they are linked.
T7 865-1086 Sentence denotes These studies, combined with state-of-the-art biochemical and structural biology experiments have started to provide an in-depth picture of how these glycans regulate the function of the proteins to which they are linked.
TextSentencer_T8 1087-1216 Sentence denotes In this review, we will discuss the biological roles assigned to EGF repeat O-glycans and the corresponding glycosyltransferases.
T8 1087-1216 Sentence denotes In this review, we will discuss the biological roles assigned to EGF repeat O-glycans and the corresponding glycosyltransferases.
T8 1087-1216 Sentence denotes In this review, we will discuss the biological roles assigned to EGF repeat O-glycans and the corresponding glycosyltransferases.
TextSentencer_T9 1217-1445 Sentence denotes Since Notch receptors are the best studied proteins with biologically-relevant O-glycans on EGF repeats, a significant part of this review is devoted to the role of these glycans in the regulation of the Notch signaling pathway.
T9 1217-1445 Sentence denotes Since Notch receptors are the best studied proteins with biologically-relevant O-glycans on EGF repeats, a significant part of this review is devoted to the role of these glycans in the regulation of the Notch signaling pathway.
T9 1217-1445 Sentence denotes Since Notch receptors are the best studied proteins with biologically-relevant O-glycans on EGF repeats, a significant part of this review is devoted to the role of these glycans in the regulation of the Notch signaling pathway.
TextSentencer_T10 1446-1564 Sentence denotes We also discuss recently identified proteins other than Notch which depend on EGF repeat glycans to function properly.
T10 1446-1564 Sentence denotes We also discuss recently identified proteins other than Notch which depend on EGF repeat glycans to function properly.
T10 1446-1564 Sentence denotes We also discuss recently identified proteins other than Notch which depend on EGF repeat glycans to function properly.
TextSentencer_T11 1565-1691 Sentence denotes Several glycosyltransferases involved in the addition or elongation of O-glycans on EGF repeats are mutated in human diseases.
T11 1565-1691 Sentence denotes Several glycosyltransferases involved in the addition or elongation of O-glycans on EGF repeats are mutated in human diseases.
T11 1565-1691 Sentence denotes Several glycosyltransferases involved in the addition or elongation of O-glycans on EGF repeats are mutated in human diseases.
TextSentencer_T12 1692-1859 Sentence denotes Therefore, mechanistic understanding of the functional roles of these carbohydrate modifications is of interest from both basic science and translational perspectives.
T12 1692-1859 Sentence denotes Therefore, mechanistic understanding of the functional roles of these carbohydrate modifications is of interest from both basic science and translational perspectives.
T12 1692-1859 Sentence denotes Therefore, mechanistic understanding of the functional roles of these carbohydrate modifications is of interest from both basic science and translational perspectives.