| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-77 |
Sentence |
denotes |
The gamma subunit modulates Na(+) and K(+) affinity of the renal Na,K-ATPase. |
| T2 |
78-139 |
Sentence |
denotes |
The Na(+),K(+)-ATPase catalyzes the active transport of ions. |
| T3 |
140-265 |
Sentence |
denotes |
It has two necessary subunits, alpha and beta, but in kidney it is also associated with a 7.4-kDa protein, the gamma subunit. |
| T4 |
266-355 |
Sentence |
denotes |
Stable transfection was used to determine the effect of gamma on Na, K-ATPase properties. |
| T5 |
356-486 |
Sentence |
denotes |
When isolated from either kidney or transfected cells, alphabetagamma had lower affinities for both Na(+) and K(+) than alphabeta. |
| T6 |
487-719 |
Sentence |
denotes |
A post-translational modification of gamma selectively eliminated the effect on Na(+) affinity, suggesting three configurations (alphabeta, alphabetagamma, and alphabetagamma*) conferring different stable properties to Na, K-ATPase. |
| T7 |
720-887 |
Sentence |
denotes |
In the nephron, segment-specific differences in Na(+) affinity have been reported that cannot be explained by the known alpha and beta subunit isoforms of Na,K-ATPase. |
| T8 |
888-952 |
Sentence |
denotes |
Immunofluorescence was used to detect gamma in rat renal cortex. |
| T9 |
953-1114 |
Sentence |
denotes |
Cortical ascending limb and some cortical collecting tubules lacked gamma, correlating with higher Na(+) affinities in those segments reported in the literature. |
| T10 |
1115-1252 |
Sentence |
denotes |
Selective expression in different segments of the nephron is consistent with a modulatory role for the gamma subunit in renal physiology. |
