| Id |
Subject |
Object |
Predicate |
Lexical cue |
| S1 |
0-155 |
Sentence |
denotes |
The human gene encoding the lectin-type oxidized LDL receptor (OLR1) is a novel member of the natural killer gene complex with a unique expression profile. |
| S2 |
156-270 |
Sentence |
denotes |
LOX-1 is an endothelial receptor for oxidized low-density lipoprotein that plays essential roles in atherogenesis. |
| S3 |
271-365 |
Sentence |
denotes |
LOX-1 has the highest homology with C-type lectin receptors expressed on natural killer cells. |
| S4 |
366-465 |
Sentence |
denotes |
In the present study, we cloned and characterized the human LOX-1 gene (HGMW-approved symbol OLR1). |
| S5 |
466-546 |
Sentence |
denotes |
The gene structure of LOX-1 resembles that of the natural killer cell receptors. |
| S6 |
547-802 |
Sentence |
denotes |
Fluorescence in situ hybridization and analyses of a yeast artificial chromosome contig revealed that the human LOX-1 gene is located in the natural killer gene complex on chromosome 12p12-p13, where the genes of the natural killer cell receptors cluster. |
| S7 |
803-976 |
Sentence |
denotes |
In contrast, the expression pattern of LOX-1 is different from that of the natural killer cell receptors; LOX-1 is expressed in vascular-rich organs, but not in lymphocytes. |
| S8 |
977-1075 |
Sentence |
denotes |
A 1753-bp fragment of the 5' flanking region of the LOX-1 gene had a functional promoter activity. |
| S9 |
1076-1249 |
Sentence |
denotes |
This region contains binding sites for several transcription factors, including the STAT family and NF-IL6, and the expression of LOX-1 was upregulated by several cytokines. |
| S10 |
1250-1386 |
Sentence |
denotes |
These results demonstrate that the human LOX-1 gene is a new member of the natural killer gene complex with a unique expression profile. |
