| Id |
Subject |
Object |
Predicate |
Lexical cue |
| S1 |
0-115 |
Sentence |
denotes |
Sex and age distribution of 1,25(OH)2D3 receptors in peripheral blood mononuclear cells from normal human subjects. |
| S2 |
116-235 |
Sentence |
denotes |
Specific receptors for 1,25 Dihydroxyvitamin D3 have been described in human peripheral blood mononuclear cells (PBMC). |
| S3 |
236-339 |
Sentence |
denotes |
We have tried to find out whether these receptors could show any difference in sex or age distribution. |
| S4 |
340-480 |
Sentence |
denotes |
Twenty two healthy men aged 21-66 yr (mean +/- SD 41.0 +/- 13.6) and nineteen healthy women aged 22-60 yr (38.9 +/- 13.9) have been studied. |
| S5 |
481-786 |
Sentence |
denotes |
The mean dissociation constant (Kd) was similar in both sexes (1.35 +/- 0.70 x 10(-10) M in males, 1.13 +/- 0.66 x 10(-10) M in females), but the concentration of binding sites (Nmax) was significantly lower in females (2.32 +/- 0.92 fmol/10(7) PBMC vs 4.43 +/- 1.38 fmol/10(7) PBMC in males; p = 0.0001). |
| S6 |
787-846 |
Sentence |
denotes |
Neither Kd nor Nmax were significantly correlated with age. |
| S7 |
847-908 |
Sentence |
denotes |
No difference was found between pre and postmenopausal women. |
| S8 |
909-1058 |
Sentence |
denotes |
Further studies are needed to elucidate if this sex difference in PBMC receptors for 1.25 Dihydroxyvitamin D3 is of any pathophysiological relevance. |
