Id |
Subject |
Object |
Predicate |
Lexical cue |
S1 |
0-87 |
Sentence |
denotes |
Phenotypic and functional studies of leukocytes in human endometrium and endometriosis. |
S2 |
88-283 |
Sentence |
denotes |
The aetiology of endometriosis, a common and disabling disorder, is presently unknown, although immune dysfunction could allow ectopic endometrial fragments to survive outside the uterine cavity. |
S3 |
284-573 |
Sentence |
denotes |
These studies investigate the relationship between leukocyte populations, steroid hormone receptor expression, proliferative activity, bcl-2 expression and apoptosis in eutopic and ectopic endometrium from women with endometriosis or adenomyosis at different phases of the menstrual cycle. |
S4 |
574-853 |
Sentence |
denotes |
Significantly increased oestrogen receptor expression, bcl-2 expression and numbers of CD8+ leukocytes were found in ectopic compared with eutopic endometrium in endometriosis, and CD56+ endometrial granulated lymphocytes (eGLs) were significantly reduced in ectopic endometrium. |
S5 |
854-922 |
Sentence |
denotes |
Apoptotic cells were rarely found in control and subject endometria. |
S6 |
923-1176 |
Sentence |
denotes |
In contrast with endometriosis, adenomyotic lesions showed identical steroid hormone receptor expression, proliferative activity, bcl-2 expression and leukocyte subpopulations to eutopic endometrium, indicating different aetiologies for these disorders. |
S7 |
1177-1332 |
Sentence |
denotes |
The unusual CD56+ CD16- eGLs present in large numbers in late secretory phase eutopic endometrium were highly purified (>98%) by immunomagnetic separation. |
S8 |
1333-1596 |
Sentence |
denotes |
Except for a negligible cytotoxic activity of eGLs from early proliferative samples, cytotoxic activity of eGLs from non-pregnant endometrium during the menstrual cycle was comparable with those in peripheral blood, predominantly CD56+ CD16+ natural killer cells. |
S9 |
1597-1758 |
Sentence |
denotes |
eGLs from non-pregnant endometrium and early pregnancy showed a variable proliferative response to 5 and 100 U/ml interleukin-2 over 48-h and 120-h time courses. |
S10 |
1759-1828 |
Sentence |
denotes |
eGLs are evidently functionally important in the eutopic endometrium. |
S11 |
1829-2047 |
Sentence |
denotes |
Their absence in endometriotic lesions together with increased CD+8 T-cell numbers and increased oestrogen receptor and bcl-2 expression may have significant effects on the development and progression of endometriosis. |