PubMed:10027623 JSONTXT 12 Projects

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Id Subject Object Predicate Lexical cue
S1 0-87 Sentence denotes Phenotypic and functional studies of leukocytes in human endometrium and endometriosis.
S2 88-283 Sentence denotes The aetiology of endometriosis, a common and disabling disorder, is presently unknown, although immune dysfunction could allow ectopic endometrial fragments to survive outside the uterine cavity.
S3 284-573 Sentence denotes These studies investigate the relationship between leukocyte populations, steroid hormone receptor expression, proliferative activity, bcl-2 expression and apoptosis in eutopic and ectopic endometrium from women with endometriosis or adenomyosis at different phases of the menstrual cycle.
S4 574-853 Sentence denotes Significantly increased oestrogen receptor expression, bcl-2 expression and numbers of CD8+ leukocytes were found in ectopic compared with eutopic endometrium in endometriosis, and CD56+ endometrial granulated lymphocytes (eGLs) were significantly reduced in ectopic endometrium.
S5 854-922 Sentence denotes Apoptotic cells were rarely found in control and subject endometria.
S6 923-1176 Sentence denotes In contrast with endometriosis, adenomyotic lesions showed identical steroid hormone receptor expression, proliferative activity, bcl-2 expression and leukocyte subpopulations to eutopic endometrium, indicating different aetiologies for these disorders.
S7 1177-1332 Sentence denotes The unusual CD56+ CD16- eGLs present in large numbers in late secretory phase eutopic endometrium were highly purified (>98%) by immunomagnetic separation.
S8 1333-1596 Sentence denotes Except for a negligible cytotoxic activity of eGLs from early proliferative samples, cytotoxic activity of eGLs from non-pregnant endometrium during the menstrual cycle was comparable with those in peripheral blood, predominantly CD56+ CD16+ natural killer cells.
S9 1597-1758 Sentence denotes eGLs from non-pregnant endometrium and early pregnancy showed a variable proliferative response to 5 and 100 U/ml interleukin-2 over 48-h and 120-h time courses.
S10 1759-1828 Sentence denotes eGLs are evidently functionally important in the eutopic endometrium.
S11 1829-2047 Sentence denotes Their absence in endometriotic lesions together with increased CD+8 T-cell numbers and increased oestrogen receptor and bcl-2 expression may have significant effects on the development and progression of endometriosis.