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PMC:1181811 / 24909-25693 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE-old TextAE

Id Subject Object Predicate Lexical cue
T4895 0-2 IN denotes In
T4897 3-13 NN denotes conclusion
T4898 13-15 , denotes ,
T4899 15-17 PRP denotes we
T4900 18-22 VBP denotes have
T4896 23-28 VBN denotes found
T4901 29-33 IN denotes that
T4903 34-45 NN denotes sensitivity
T4904 46-48 IN denotes to
T4905 49-52 DT denotes the
T4907 53-59 JJ denotes bitter
T4909 59-60 HYPH denotes -
T4908 60-67 VBG denotes tasting
T4910 68-77 NN denotes substance
T4906 78-85 NN denotes quinine
T4911 85-87 , denotes ,
T4912 87-89 IN denotes as
T4913 90-97 VBN denotes assayed
T4914 98-100 IN denotes by
T4915 101-102 DT denotes a
T4917 103-108 NN denotes taste
T4918 109-117 JJ denotes specific
T4919 118-123 JJ denotes brief
T4921 123-124 HYPH denotes -
T4920 124-130 NN denotes access
T4916 131-135 NN denotes test
T4922 135-137 , denotes ,
T4902 137-139 VBZ denotes is
T4923 140-141 DT denotes a
T4925 142-151 JJ denotes polygenic
T4924 152-157 NN denotes trait
T4926 158-160 IN denotes in
T4927 161-165 NNS denotes mice
T4928 165-166 . denotes .
T4929 166-276 sentence denotes However, the major mechanism for quinine taste transduction is likely dependent on one or more T2R receptors.
T4930 167-174 RB denotes However
T4932 174-176 , denotes ,
T4933 176-179 DT denotes the
T4935 180-185 JJ denotes major
T4934 186-195 NN denotes mechanism
T4936 196-199 IN denotes for
T4937 200-207 NN denotes quinine
T4938 208-213 NN denotes taste
T4939 214-226 NN denotes transduction
T4931 227-229 VBZ denotes is
T4940 230-236 RB denotes likely
T4941 237-246 JJ denotes dependent
T4942 247-249 IN denotes on
T4943 250-253 CD denotes one
T4945 254-256 CC denotes or
T4946 257-261 JJR denotes more
T4947 262-265 NN denotes T2R
T4944 266-275 NNS denotes receptors
T4948 275-276 . denotes .
T4949 276-465 sentence denotes Most Tas2r genes in the distal chromosome 6 cluster are polymorphic across inbred strains of mice, and this cluster forms a single haplotype that correlates with quinine taste sensitivity.
T4950 277-281 JJS denotes Most
T4952 282-287 NN denotes Tas2r
T4951 288-293 NNS denotes genes
T4954 294-296 IN denotes in
T4955 297-300 DT denotes the
T4957 301-307 JJ denotes distal
T4958 308-318 NN denotes chromosome
T4959 319-320 CD denotes 6
T4956 321-328 NN denotes cluster
T4953 329-332 VBP denotes are
T4960 333-344 JJ denotes polymorphic
T4961 345-351 IN denotes across
T4962 352-358 JJ denotes inbred
T4963 359-366 NNS denotes strains
T4964 367-369 IN denotes of
T4965 370-374 NNS denotes mice
T4966 374-376 , denotes ,
T4967 376-379 CC denotes and
T4968 380-384 DT denotes this
T4969 385-392 NN denotes cluster
T4970 393-398 VBZ denotes forms
T4971 399-400 DT denotes a
T4973 401-407 JJ denotes single
T4972 408-417 NN denotes haplotype
T4974 418-422 WDT denotes that
T4975 423-433 VBZ denotes correlates
T4976 434-438 IN denotes with
T4977 439-446 NN denotes quinine
T4978 447-452 NN denotes taste
T4979 453-464 NN denotes sensitivity
T4980 464-465 . denotes .
T4981 465-631 sentence denotes The numerous differences in T2R protein sequence between these two mouse strains suggests that T2Rs are broadly tuned receptors quite tolerant to sequence variation.
T4982 466-469 DT denotes The
T4984 470-478 JJ denotes numerous
T4983 479-490 NNS denotes differences
T4986 491-493 IN denotes in
T4987 494-497 NN denotes T2R
T4989 498-505 NN denotes protein
T4988 506-514 NN denotes sequence
T4990 515-522 IN denotes between
T4991 523-528 DT denotes these
T4993 529-532 CD denotes two
T4994 533-538 NN denotes mouse
T4992 539-546 NNS denotes strains
T4985 547-555 VBZ denotes suggests
T4995 556-560 IN denotes that
T4997 561-565 NNS denotes T2Rs
T4996 566-569 VBP denotes are
T4998 570-577 RB denotes broadly
T4999 578-583 VBN denotes tuned
T5000 584-593 NNS denotes receptors
T5001 594-599 RB denotes quite
T5002 600-608 JJ denotes tolerant
T5003 609-611 IN denotes to
T5004 612-620 NN denotes sequence
T5005 621-630 NN denotes variation
T5006 630-631 . denotes .
T5007 631-784 sentence denotes This tolerance may help to preserve the ability of T2R-expressing, bitter-sensitive taste cells to respond to a wide array of potentially toxic stimuli.
T5008 632-636 DT denotes This
T5009 637-646 NN denotes tolerance
T5011 647-650 MD denotes may
T5010 651-655 VB denotes help
T5012 656-658 TO denotes to
T5013 659-667 VB denotes preserve
T5014 668-671 DT denotes the
T5015 672-679 NN denotes ability
T5016 680-682 IN denotes of
T5017 683-686 NN denotes T2R
T5019 686-687 HYPH denotes -
T5018 687-697 VBG denotes expressing
T5021 697-699 , denotes ,
T5022 699-705 JJ denotes bitter
T5024 705-706 HYPH denotes -
T5023 706-715 JJ denotes sensitive
T5025 716-721 NN denotes taste
T5020 722-727 NNS denotes cells
T5026 728-730 TO denotes to
T5027 731-738 VB denotes respond
T5028 739-741 IN denotes to
T5029 742-743 DT denotes a
T5031 744-748 JJ denotes wide
T5030 749-754 NN denotes array
T5032 755-757 IN denotes of
T5033 758-769 RB denotes potentially
T5034 770-775 JJ denotes toxic
T5035 776-783 NNS denotes stimuli
T5036 783-784 . denotes .
R3566 T4895 T4896 prep In,found
R3567 T4897 T4895 pobj conclusion,In
R3568 T4898 T4896 punct ", ",found
R3569 T4899 T4896 nsubj we,found
R3570 T4900 T4896 aux have,found
R3571 T4901 T4902 mark that,is
R3572 T4902 T4896 ccomp is,found
R3573 T4903 T4902 nsubj sensitivity,is
R3574 T4904 T4903 prep to,sensitivity
R3575 T4905 T4906 det the,quinine
R3576 T4906 T4904 pobj quinine,to
R3577 T4907 T4908 amod bitter,tasting
R3578 T4908 T4906 nmod tasting,quinine
R3579 T4909 T4908 punct -,tasting
R3580 T4910 T4906 compound substance,quinine
R3581 T4911 T4902 punct ", ",is
R3582 T4912 T4913 mark as,assayed
R3583 T4913 T4902 advcl assayed,is
R3584 T4914 T4913 agent by,assayed
R3585 T4915 T4916 det a,test
R3586 T4916 T4914 pobj test,by
R3587 T4917 T4918 npadvmod taste,specific
R3588 T4918 T4916 amod specific,test
R3589 T4919 T4920 amod brief,access
R3590 T4920 T4916 compound access,test
R3591 T4921 T4920 punct -,access
R3592 T4922 T4902 punct ", ",is
R3593 T4923 T4924 det a,trait
R3594 T4924 T4902 attr trait,is
R3595 T4925 T4924 amod polygenic,trait
R3596 T4926 T4902 prep in,is
R3597 T4927 T4926 pobj mice,in
R3598 T4928 T4896 punct .,found
R3599 T4930 T4931 advmod However,is
R3600 T4932 T4931 punct ", ",is
R3601 T4933 T4934 det the,mechanism
R3602 T4934 T4931 nsubj mechanism,is
R3603 T4935 T4934 amod major,mechanism
R3604 T4936 T4934 prep for,mechanism
R3605 T4937 T4938 compound quinine,taste
R3606 T4938 T4939 compound taste,transduction
R3607 T4939 T4936 pobj transduction,for
R3608 T4940 T4931 advmod likely,is
R3609 T4941 T4931 acomp dependent,is
R3610 T4942 T4941 prep on,dependent
R3611 T4943 T4944 nummod one,receptors
R3612 T4944 T4942 pobj receptors,on
R3613 T4945 T4943 cc or,one
R3614 T4946 T4943 conj more,one
R3615 T4947 T4944 compound T2R,receptors
R3616 T4948 T4931 punct .,is
R3617 T4950 T4951 amod Most,genes
R3618 T4951 T4953 nsubj genes,are
R3619 T4952 T4951 compound Tas2r,genes
R3620 T4954 T4951 prep in,genes
R3621 T4955 T4956 det the,cluster
R3622 T4956 T4954 pobj cluster,in
R3623 T4957 T4956 amod distal,cluster
R3624 T4958 T4956 nmod chromosome,cluster
R3625 T4959 T4958 nummod 6,chromosome
R3626 T4960 T4953 acomp polymorphic,are
R3627 T4961 T4953 prep across,are
R3628 T4962 T4963 amod inbred,strains
R3629 T4963 T4961 pobj strains,across
R3630 T4964 T4963 prep of,strains
R3631 T4965 T4964 pobj mice,of
R3632 T4966 T4953 punct ", ",are
R3633 T4967 T4953 cc and,are
R3634 T4968 T4969 det this,cluster
R3635 T4969 T4970 nsubj cluster,forms
R3636 T4970 T4953 conj forms,are
R3637 T4971 T4972 det a,haplotype
R3638 T4972 T4970 dobj haplotype,forms
R3639 T4973 T4972 amod single,haplotype
R3640 T4974 T4975 dep that,correlates
R3641 T4975 T4972 relcl correlates,haplotype
R3642 T4976 T4975 prep with,correlates
R3643 T4977 T4978 compound quinine,taste
R3644 T4978 T4979 compound taste,sensitivity
R3645 T4979 T4976 pobj sensitivity,with
R3646 T4980 T4970 punct .,forms
R3647 T4982 T4983 det The,differences
R3648 T4983 T4985 nsubj differences,suggests
R3649 T4984 T4983 amod numerous,differences
R3650 T4986 T4983 prep in,differences
R3651 T4987 T4988 compound T2R,sequence
R3652 T4988 T4986 pobj sequence,in
R3653 T4989 T4988 compound protein,sequence
R3654 T4990 T4983 prep between,differences
R3655 T4991 T4992 det these,strains
R3656 T4992 T4990 pobj strains,between
R3657 T4993 T4992 nummod two,strains
R3658 T4994 T4992 compound mouse,strains
R3659 T4995 T4996 mark that,are
R3660 T4996 T4985 ccomp are,suggests
R3661 T4997 T4996 nsubj T2Rs,are
R3662 T4998 T4999 advmod broadly,tuned
R3663 T4999 T5000 amod tuned,receptors
R3664 T5000 T4996 attr receptors,are
R3665 T5001 T5002 advmod quite,tolerant
R3666 T5002 T5000 amod tolerant,receptors
R3667 T5003 T5002 prep to,tolerant
R3668 T5004 T5005 compound sequence,variation
R3669 T5005 T5003 pobj variation,to
R3670 T5006 T4985 punct .,suggests
R3671 T5008 T5009 det This,tolerance
R3672 T5009 T5010 nsubj tolerance,help
R3673 T5011 T5010 aux may,help
R3674 T5012 T5013 aux to,preserve
R3675 T5013 T5010 xcomp preserve,help
R3676 T5014 T5015 det the,ability
R3677 T5015 T5013 dobj ability,preserve
R3678 T5016 T5015 prep of,ability
R3679 T5017 T5018 npadvmod T2R,expressing
R3680 T5018 T5020 amod expressing,cells
R3681 T5019 T5018 punct -,expressing
R3682 T5020 T5016 pobj cells,of
R3683 T5021 T5020 punct ", ",cells
R3684 T5022 T5023 amod bitter,sensitive
R3685 T5023 T5020 amod sensitive,cells
R3686 T5024 T5023 punct -,sensitive
R3687 T5025 T5020 compound taste,cells
R3688 T5026 T5027 aux to,respond
R3689 T5027 T5015 acl respond,ability
R3690 T5028 T5027 prep to,respond
R3691 T5029 T5030 det a,array
R3692 T5030 T5028 pobj array,to
R3693 T5031 T5030 amod wide,array
R3694 T5032 T5030 prep of,array
R3695 T5033 T5034 advmod potentially,toxic
R3696 T5034 T5035 amod toxic,stimuli
R3697 T5035 T5032 pobj stimuli,of
R3698 T5036 T5010 punct .,help