| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T512 |
17-26 |
Regulation |
denotes |
modulates |
| T513 |
17-26 |
Regulation |
denotes |
modulates |
| T510 |
31-38 |
Binding |
denotes |
binding |
| T511 |
31-38 |
Binding |
denotes |
binding |
| T507 |
42-64 |
Protein |
denotes |
nuclear factors κB, AT |
| T508 |
69-73 |
Protein |
denotes |
IL-6 |
| T509 |
119-138 |
Protein |
denotes |
IL-1β/IL-1 receptor |
| T521 |
631-641 |
Positive_regulation |
denotes |
activation |
| T522 |
631-641 |
Positive_regulation |
denotes |
activation |
| T523 |
631-641 |
Positive_regulation |
denotes |
activation |
| T514 |
645-666 |
Protein |
denotes |
nuclear factor (NF)κB |
| T515 |
668-687 |
Protein |
denotes |
NFinterleukin(IL)-6 |
| T516 |
692-696 |
Protein |
denotes |
NFAT |
| T524 |
750-760 |
Gene_expression |
denotes |
production |
| T525 |
750-760 |
Gene_expression |
denotes |
production |
| T526 |
750-760 |
Gene_expression |
denotes |
production |
| T527 |
750-760 |
Gene_expression |
denotes |
production |
| T517 |
764-769 |
Protein |
denotes |
IL-1β |
| T518 |
771-775 |
Protein |
denotes |
IL-6 |
| T519 |
777-800 |
Protein |
denotes |
tumor necrosis factor α |
| T520 |
804-816 |
Protein |
denotes |
interferon γ |
| T528 |
817-824 |
Positive_regulation |
denotes |
induced |
| T529 |
817-824 |
Positive_regulation |
denotes |
induced |
| T530 |
817-824 |
Positive_regulation |
denotes |
induced |
| T531 |
817-824 |
Positive_regulation |
denotes |
induced |
| T538 |
882-889 |
Positive_regulation |
denotes |
induced |
| T535 |
904-910 |
Gene_expression |
denotes |
amount |
| T532 |
914-918 |
Protein |
denotes |
IL-8 |
| T536 |
961-968 |
Binding |
denotes |
binding |
| T537 |
961-968 |
Binding |
denotes |
binding |
| T533 |
972-976 |
Protein |
denotes |
NFκB |
| T534 |
1004-1017 |
Protein |
denotes |
IL-8 promoter |
| T539 |
1034-1046 |
Protein |
denotes |
IL-1receptor |
| T540 |
1162-1166 |
Protein |
denotes |
IL-8 |
| T547 |
1192-1199 |
Positive_regulation |
denotes |
induced |
| T548 |
1192-1199 |
Positive_regulation |
denotes |
induced |
| T544 |
1212-1219 |
Binding |
denotes |
binding |
| T545 |
1212-1219 |
Binding |
denotes |
binding |
| T541 |
1231-1242 |
Protein |
denotes |
NFIL-6 site |
| T542 |
1253-1262 |
Protein |
denotes |
NFAT site |
| T543 |
1274-1289 |
Protein |
denotes |
IL-1RA promoter |
| T546 |
1301-1310 |
Positive_regulation |
denotes |
confirmed |
| T557 |
1451-1459 |
Positive_regulation |
denotes |
elevated |
| T558 |
1451-1459 |
Positive_regulation |
denotes |
elevated |
| T559 |
1451-1459 |
Positive_regulation |
denotes |
elevated |
| T553 |
1496-1503 |
Binding |
denotes |
binding |
| T554 |
1496-1503 |
Binding |
denotes |
binding |
| T555 |
1496-1503 |
Binding |
denotes |
binding |
| T549 |
1507-1511 |
Protein |
denotes |
NFκB |
| T550 |
1513-1519 |
Protein |
denotes |
NFIL-6 |
| T551 |
1524-1528 |
Protein |
denotes |
NFAT |
| T556 |
1555-1563 |
Positive_regulation |
denotes |
increase |
| T552 |
1567-1573 |
Protein |
denotes |
IL-1RA |
| T562 |
1656-1665 |
Negative_regulation |
denotes |
reduction |
| T563 |
1656-1665 |
Negative_regulation |
denotes |
reduction |
| T560 |
1669-1674 |
Protein |
denotes |
IL-1β |
| T561 |
1679-1683 |
Protein |
denotes |
IL-6 |
| T567 |
1837-1846 |
Negative_regulation |
denotes |
decreased |
| T564 |
1867-1871 |
Protein |
denotes |
IL-1 |
| T566 |
1882-1892 |
Gene_expression |
denotes |
production |
| T565 |
1896-1900 |
Protein |
denotes |
IL-2 |
| T569 |
2181-2191 |
Regulation |
denotes |
regulation |
| T568 |
2199-2210 |
Protein |
denotes |
IL-1RA gene |
| T1973 |
2732-2740 |
Protein |
denotes |
Dectin-1 |
| T1974 |
2779-2807 |
Protein |
denotes |
pattern recognition receptor |
| T1975 |
2809-2812 |
Protein |
denotes |
PRR |
| T1979 |
2985-2992 |
Binding |
denotes |
binding |
| T1976 |
3007-3015 |
Protein |
denotes |
Dectin-1 |
| T1982 |
3016-3024 |
Positive_regulation |
denotes |
resulted |
| T1983 |
3016-3024 |
Positive_regulation |
denotes |
resulted |
| T1980 |
3028-3038 |
Gene_expression |
denotes |
production |
| T1981 |
3028-3038 |
Gene_expression |
denotes |
production |
| T1977 |
3042-3046 |
Protein |
denotes |
TNFα |
| T1978 |
3055-3075 |
Protein |
denotes |
Toll-like receptor 2 |
| T1986 |
3184-3192 |
Positive_regulation |
denotes |
activate |
| T1987 |
3184-3192 |
Positive_regulation |
denotes |
activate |
| T1984 |
3193-3197 |
Protein |
denotes |
NFκB |
| T1985 |
3202-3208 |
Protein |
denotes |
NFIL-6 |
| T1988 |
3298-3302 |
Protein |
denotes |
NFκB |
| T1992 |
3420-3429 |
Localization |
denotes |
secretion |
| T1993 |
3420-3429 |
Localization |
denotes |
secretion |
| T1994 |
3420-3429 |
Localization |
denotes |
secretion |
| T1989 |
3461-3465 |
Protein |
denotes |
IL-1 |
| T1990 |
3467-3471 |
Protein |
denotes |
IL-6 |
| T1991 |
3473-3477 |
Protein |
denotes |
TNFα |
| T1996 |
3513-3523 |
Gene_expression |
denotes |
production |
| T1995 |
3565-3569 |
Protein |
denotes |
IL-1 |
| T1998 |
3763-3770 |
Gene_expression |
denotes |
produce |
| T1997 |
3771-3775 |
Protein |
denotes |
IL-8 |
| T2002 |
4094-4104 |
Negative_regulation |
denotes |
inhibition |
| T1999 |
4108-4112 |
Protein |
denotes |
NFκB |
| T2000 |
4136-4161 |
Protein |
denotes |
phosphoinositide-3-kinase |
| T2001 |
4163-4167 |
Protein |
denotes |
PI3K |
| T2003 |
4904-4923 |
Protein |
denotes |
superantigen TSST-1 |
| T2014 |
5025-5035 |
Gene_expression |
denotes |
production |
| T2015 |
5025-5035 |
Gene_expression |
denotes |
production |
| T2004 |
5048-5052 |
Protein |
denotes |
TNFα |
| T2005 |
5054-5059 |
Protein |
denotes |
IL-1β |
| T2006 |
5061-5071 |
Protein |
denotes |
IL-6, IL-8 |
| T2007 |
5076-5082 |
Protein |
denotes |
IL-1RA |
| T2008 |
5108-5112 |
Protein |
denotes |
IFNγ |
| T2009 |
5114-5118 |
Protein |
denotes |
IL-2 |
| T2010 |
5120-5124 |
Protein |
denotes |
IL-4 |
| T2011 |
5126-5131 |
Protein |
denotes |
IL-10 |
| T2012 |
5133-5138 |
Protein |
denotes |
IL-12 |
| T2013 |
5143-5148 |
Protein |
denotes |
TGFβ1 |
| T2016 |
5172-5182 |
Protein |
denotes |
NFκB sites |
| T2017 |
5228-5230 |
Protein |
denotes |
κ3 |
| T2018 |
5289-5298 |
Protein |
denotes |
NFAT site |
| T2019 |
5308-5321 |
Protein |
denotes |
IFNγ promoter |
| T2020 |
5323-5327 |
Protein |
denotes |
ATP2 |
| T2021 |
5446-5452 |
Protein |
denotes |
IL-1RA |
| T2023 |
5468-5475 |
Binding |
denotes |
binding |
| T2022 |
5508-5523 |
Protein |
denotes |
IL-1RA promoter |
| T2028 |
5596-5601 |
Entity |
denotes |
LRE-1 |
| T2024 |
5627-5642 |
Protein |
denotes |
IL-1RA promoter |
| T2025 |
5654-5658 |
Protein |
denotes |
NFκB |
| T2026 |
5660-5664 |
Protein |
denotes |
PU.1 |
| T2027 |
5669-5681 |
Protein |
denotes |
NFIL-6 sites |
| T2029 |
5822-5837 |
Protein |
denotes |
IL-1RA promoter |
| T3710 |
5857-5867 |
Positive_regulation |
denotes |
activities |
| T3704 |
5871-5875 |
Protein |
denotes |
NFκB |
| T3705 |
5877-5883 |
Protein |
denotes |
NFIL-6 |
| T3706 |
5888-5892 |
Protein |
denotes |
NFAT |
| T3707 |
5916-5920 |
Protein |
denotes |
TNFα |
| T3708 |
5922-5926 |
Protein |
denotes |
IL-6 |
| T3709 |
5931-5945 |
Protein |
denotes |
IFNγ promoters |
| T3719 |
6068-6075 |
Binding |
denotes |
binding |
| T3720 |
6068-6075 |
Binding |
denotes |
binding |
| T3721 |
6068-6075 |
Binding |
denotes |
binding |
| T3722 |
6068-6075 |
Binding |
denotes |
binding |
| T3711 |
6079-6083 |
Protein |
denotes |
NFκB |
| T3712 |
6098-6104 |
Protein |
denotes |
NFIL-6 |
| T3713 |
6161-6177 |
Protein |
denotes |
κ1, κ2, κ3 sites |
| T3714 |
6187-6200 |
Protein |
denotes |
TNFα promoter |
| T3715 |
6223-6236 |
Protein |
denotes |
IL-8 promoter |
| T3716 |
6238-6253 |
Protein |
denotes |
NFIL-6consensus |
| T3717 |
6263-6285 |
Protein |
denotes |
IL-6 promoter; Table 1 |
| T3718 |
6287-6294 |
Protein |
denotes |
Fig. 1A |
| T3723 |
6446-6450 |
Protein |
denotes |
NFκB |
| T3724 |
6475-6488 |
Protein |
denotes |
IL-8 promoter |
| T3728 |
6528-6535 |
Binding |
denotes |
binding |
| T3729 |
6528-6535 |
Binding |
denotes |
binding |
| T3730 |
6528-6535 |
Binding |
denotes |
binding |
| T3725 |
6539-6547 |
Protein |
denotes |
NFκB p65 |
| T3731 |
6564-6570 |
Negative_regulation |
denotes |
degree |
| T3732 |
6564-6570 |
Negative_regulation |
denotes |
degree |
| T3733 |
6564-6570 |
Negative_regulation |
denotes |
degree |
| T3734 |
6564-6570 |
Negative_regulation |
denotes |
degree |
| T3735 |
6564-6570 |
Negative_regulation |
denotes |
degree |
| T3726 |
6574-6577 |
Protein |
denotes |
p50 |
| T3727 |
6579-6586 |
Protein |
denotes |
Fig. 1A |
| T3739 |
6673-6680 |
Binding |
denotes |
binding |
| T3740 |
6673-6680 |
Binding |
denotes |
binding |
| T3736 |
6684-6692 |
Protein |
denotes |
NFκB p65 |
| T3737 |
6718-6721 |
Protein |
denotes |
p50 |
| T3738 |
6731-6734 |
Protein |
denotes |
p52 |
| T3741 |
6739-6747 |
Gene_expression |
denotes |
negative |
| T3742 |
6831-6835 |
Protein |
denotes |
NFκB |
| T3745 |
6836-6843 |
Binding |
denotes |
binding |
| T3746 |
6836-6843 |
Binding |
denotes |
binding |
| T3743 |
6863-6876 |
Protein |
denotes |
TNFα promoter |
| T3748 |
6920-6929 |
Negative_regulation |
denotes |
decreased |
| T3744 |
6949-6953 |
Protein |
denotes |
NFκB |
| T3747 |
6954-6961 |
Binding |
denotes |
binding |
| T3752 |
7201-7208 |
Binding |
denotes |
binding |
| T3749 |
7235-7239 |
Protein |
denotes |
NFAT |
| T3750 |
7261-7274 |
Protein |
denotes |
IFNγ promoter |
| T3751 |
7276-7283 |
Protein |
denotes |
Fig. 1A |
| T3753 |
7308-7321 |
Protein |
denotes |
NFAT subunits |
| T3757 |
7348-7355 |
Binding |
denotes |
binding |
| T3754 |
7359-7365 |
Protein |
denotes |
NFATc2 |
| T3758 |
7382-7388 |
Negative_regulation |
denotes |
degree |
| T3759 |
7382-7388 |
Negative_regulation |
denotes |
degree |
| T3755 |
7392-7398 |
Protein |
denotes |
NFATc1 |
| T3756 |
7400-7403 |
Protein |
denotes |
Fig |
| T21533 |
8976-8983 |
Binding |
denotes |
binding |
| T21532 |
8976-8983 |
Binding |
denotes |
binding |
| T21531 |
8976-8983 |
Binding |
denotes |
binding |
| T21528 |
8987-8991 |
Protein |
denotes |
NFAT |
| T21529 |
8993-8997 |
Protein |
denotes |
NFκB |
| T21530 |
9002-9008 |
Protein |
denotes |
NFIL-6 |
| T21534 |
9145-9149 |
Protein |
denotes |
NFAT |
| T21535 |
9151-9155 |
Protein |
denotes |
NFκB |
| T21536 |
9157-9163 |
Protein |
denotes |
NFIL-6 |
| T21537 |
9167-9192 |
Protein |
denotes |
NFκB-IL-8 oligonucleotide |
| T21538 |
9220-9224 |
Protein |
denotes |
IFNγ |
| T21539 |
9226-9230 |
Protein |
denotes |
TNFα |
| T21540 |
9232-9236 |
Protein |
denotes |
IL-6 |
| T21541 |
9336-9344 |
Protein |
denotes |
NFAT-DNA |
| T21542 |
9346-9354 |
Protein |
denotes |
NFκB-DNA |
| T21543 |
9356-9366 |
Protein |
denotes |
NFIL-6-DNA |
| T21544 |
9370-9391 |
Protein |
denotes |
NFκB-IL-8-DNA complex |
| T21545 |
9478-9496 |
Protein |
denotes |
NFκB-IL-8-DNA-anti |
| T21546 |
9497-9500 |
Protein |
denotes |
p65 |
| T21547 |
9506-9509 |
Protein |
denotes |
p50 |
| T21551 |
9610-9617 |
Binding |
denotes |
binding |
| T21548 |
9621-9625 |
Protein |
denotes |
NFκB |
| T21549 |
9661-9667 |
Protein |
denotes |
TSST-1 |
| T21550 |
9669-9671 |
Protein |
denotes |
GP |
| T21552 |
9890-9898 |
Protein |
denotes |
NFκB-DNA |
| T22409 |
10215-10219 |
Protein |
denotes |
NFκB |
| T22410 |
10220-10223 |
Protein |
denotes |
p65 |
| T22411 |
10224-10227 |
Protein |
denotes |
p50 |
| T22412 |
10232-10238 |
Protein |
denotes |
NFATc2 |
| T22413 |
10239-10241 |
Protein |
denotes |
c1 |
| T22419 |
10274-10281 |
Binding |
denotes |
binding |
| T22418 |
10274-10281 |
Binding |
denotes |
binding |
| T22417 |
10274-10281 |
Binding |
denotes |
binding |
| T22416 |
10274-10281 |
Binding |
denotes |
binding |
| T22415 |
10274-10281 |
Binding |
denotes |
binding |
| T22414 |
10274-10281 |
Binding |
denotes |
binding |
| T22420 |
10370-10374 |
Protein |
denotes |
NFκB |
| T22421 |
10379-10383 |
Protein |
denotes |
NFAT |
| T22422 |
10498-10523 |
Protein |
denotes |
recombinant proteins NFκB |
| T22423 |
10524-10527 |
Protein |
denotes |
p52 |
| T22424 |
10529-10534 |
Protein |
denotes |
c-rel |
| T22435 |
10581-10589 |
Gene_expression |
denotes |
positive |
| T22434 |
10581-10589 |
Gene_expression |
denotes |
positive |
| T22433 |
10581-10589 |
Gene_expression |
denotes |
positive |
| T22425 |
10594-10602 |
Protein |
denotes |
NFκB p50 |
| T22426 |
10604-10607 |
Protein |
denotes |
p65 |
| T22427 |
10612-10622 |
Protein |
denotes |
for NFATc1 |
| T22428 |
10624-10626 |
Protein |
denotes |
c2 |
| T22439 |
10700-10708 |
Gene_expression |
denotes |
positive |
| T22438 |
10700-10708 |
Gene_expression |
denotes |
positive |
| T22437 |
10700-10708 |
Gene_expression |
denotes |
positive |
| T22436 |
10700-10708 |
Gene_expression |
denotes |
positive |
| T22429 |
10713-10721 |
Protein |
denotes |
NFκB p65 |
| T22430 |
10723-10726 |
Protein |
denotes |
p50 |
| T22431 |
10731-10738 |
Protein |
denotes |
NFAT c2 |
| T22432 |
10740-10742 |
Protein |
denotes |
c1 |
| T6214 |
10960-10970 |
Protein |
denotes |
TNFα, IL-8 |
| T6215 |
10972-10976 |
Protein |
denotes |
IL-6 |
| T6216 |
10981-10995 |
Protein |
denotes |
IFNγ promoters |
| T6224 |
11063-11073 |
Gene_expression |
denotes |
production |
| T6223 |
11063-11073 |
Gene_expression |
denotes |
production |
| T6222 |
11063-11073 |
Gene_expression |
denotes |
production |
| T6221 |
11063-11073 |
Gene_expression |
denotes |
production |
| T6217 |
11077-11081 |
Protein |
denotes |
TNFα |
| T6218 |
11083-11087 |
Protein |
denotes |
IL-8 |
| T6219 |
11089-11093 |
Protein |
denotes |
IL-6 |
| T6220 |
11095-11099 |
Protein |
denotes |
IFNγ |
| T6225 |
11704-11709 |
Protein |
denotes |
IL-1β |
| T6226 |
11710-11720 |
Gene_expression |
denotes |
production |
| T6229 |
11796-11809 |
Positive_regulation |
denotes |
up-regulation |
| T6227 |
11813-11818 |
Protein |
denotes |
IL-1β |
| T6228 |
11819-11829 |
Gene_expression |
denotes |
production |
| T6232 |
11919-11928 |
Negative_regulation |
denotes |
reduction |
| T6230 |
11932-11937 |
Protein |
denotes |
IL-1β |
| T6231 |
12001-12007 |
Protein |
denotes |
TSST-1 |
| T6234 |
12104-12113 |
Negative_regulation |
denotes |
reduction |
| T6233 |
12146-12151 |
Protein |
denotes |
IL-1β |
| T23019 |
12189-12194 |
Protein |
denotes |
IL-1β |
| T23021 |
12199-12213 |
Negative_regulation |
denotes |
down-regulated |
| T23020 |
12267-12273 |
Protein |
denotes |
TSST-1 |
| T23022 |
12297-12302 |
Protein |
denotes |
IL-1β |
| T23023 |
12303-12313 |
Gene_expression |
denotes |
production |
| T23027 |
12467-12476 |
Negative_regulation |
denotes |
reduction |
| T23024 |
12480-12485 |
Protein |
denotes |
IL-1β |
| T23026 |
12486-12496 |
Gene_expression |
denotes |
production |
| T23025 |
12536-12542 |
Protein |
denotes |
TSST-1 |
| T23028 |
12652-12657 |
Protein |
denotes |
IL-1β |
| T23029 |
12748-12754 |
Protein |
denotes |
IL-1RA |
| T23030 |
12824-12830 |
Protein |
denotes |
TSST-1 |
| T23031 |
12854-12860 |
Protein |
denotes |
IL-1RA |
| T23032 |
12861-12871 |
Gene_expression |
denotes |
production |
| T23033 |
13297-13303 |
Protein |
denotes |
IL-1RA |
| T6237 |
13405-13412 |
Positive_regulation |
denotes |
induced |
| T6235 |
13436-13440 |
Protein |
denotes |
IL-6 |
| T6240 |
13470-13480 |
Regulation |
denotes |
alteration |
| T6239 |
13488-13499 |
Positive_regulation |
denotes |
LPS-induced |
| T6236 |
13500-13504 |
Protein |
denotes |
IL-6 |
| T6238 |
13505-13515 |
Gene_expression |
denotes |
production |
| T6244 |
13554-13563 |
Negative_regulation |
denotes |
decreased |
| T6241 |
13564-13568 |
Protein |
denotes |
IL-6 |
| T6243 |
13569-13579 |
Gene_expression |
denotes |
production |
| T6242 |
13613-13619 |
Protein |
denotes |
TSST-1 |
| T6245 |
14083-14089 |
Protein |
denotes |
TSST-1 |
| T6246 |
14093-14107 |
Protein |
denotes |
GP/TSST-1 calc |
| T6247 |
14158-14162 |
Protein |
denotes |
IL-8 |
| T6248 |
14164-14170 |
Protein |
denotes |
IL-1RA |
| T6250 |
14203-14211 |
Gene_expression |
denotes |
produced |
| T6249 |
14203-14211 |
Gene_expression |
denotes |
produced |
| T6253 |
14368-14373 |
Regulation |
denotes |
alter |
| T6251 |
14400-14406 |
Protein |
denotes |
IL-1RA |
| T6252 |
14407-14417 |
Gene_expression |
denotes |
production |
| T6257 |
14473-14481 |
Positive_regulation |
denotes |
increase |
| T6254 |
14485-14491 |
Protein |
denotes |
IL-1RA |
| T6256 |
14492-14502 |
Gene_expression |
denotes |
production |
| T6255 |
14539-14545 |
Protein |
denotes |
TSST-1 |
| T6259 |
14687-14695 |
Positive_regulation |
denotes |
elevated |
| T6258 |
14725-14731 |
Protein |
denotes |
IL-1RA |
| T6265 |
14794-14804 |
Positive_regulation |
denotes |
GP-induced |
| T6264 |
14794-14804 |
Positive_regulation |
denotes |
GP-induced |
| T6260 |
14805-14809 |
Protein |
denotes |
IL-8 |
| T6261 |
14814-14820 |
Protein |
denotes |
IL-1RA |
| T6263 |
14821-14832 |
Gene_expression |
denotes |
productions |
| T6262 |
14821-14832 |
Gene_expression |
denotes |
productions |
| T6266 |
14915-14919 |
Protein |
denotes |
IL-8 |
| T6267 |
14924-14930 |
Protein |
denotes |
IL-1RA |
| T6271 |
15009-15016 |
Positive_regulation |
denotes |
induced |
| T6270 |
15009-15016 |
Positive_regulation |
denotes |
induced |
| T6268 |
15035-15039 |
Protein |
denotes |
IL-8 |
| T6269 |
15044-15050 |
Protein |
denotes |
IL-1RA |
| T6272 |
15142-15146 |
Protein |
denotes |
TNFα |
| T6273 |
15147-15157 |
Gene_expression |
denotes |
production |
| T6276 |
15280-15286 |
Regulation |
denotes |
change |
| T6274 |
15291-15295 |
Protein |
denotes |
TNFα |
| T6275 |
15296-15306 |
Gene_expression |
denotes |
production |
| T6277 |
15449-15453 |
Protein |
denotes |
TNFα |
| T6278 |
15454-15463 |
Localization |
denotes |
secretion |
| T6279 |
15598-15602 |
Protein |
denotes |
IFNγ |
| T6280 |
15603-15613 |
Gene_expression |
denotes |
production |
| T6287 |
15691-15699 |
Positive_regulation |
denotes |
increase |
| T6285 |
15691-15699 |
Positive_regulation |
denotes |
increase |
| T6281 |
15703-15707 |
Protein |
denotes |
IFNγ |
| T6284 |
15708-15718 |
Gene_expression |
denotes |
production |
| T6286 |
15798-15813 |
Negative_regulation |
denotes |
down-regulation |
| T6282 |
15871-15877 |
Protein |
denotes |
TSST-1 |
| T6283 |
15881-15895 |
Protein |
denotes |
GP/TSST-1 calc |
| T6288 |
15922-15926 |
Protein |
denotes |
IL-2 |
| T6289 |
15928-15939 |
Protein |
denotes |
IL-12, IL-4 |
| T6290 |
15941-15946 |
Protein |
denotes |
IL-10 |
| T6291 |
15948-15953 |
Protein |
denotes |
TGFβ1 |
| T6299 |
15958-15968 |
Gene_expression |
denotes |
production |
| T6298 |
15958-15968 |
Gene_expression |
denotes |
production |
| T6297 |
15958-15968 |
Gene_expression |
denotes |
production |
| T6296 |
15958-15968 |
Gene_expression |
denotes |
production |
| T6292 |
15972-15976 |
Protein |
denotes |
IL-2 |
| T6293 |
15978-15989 |
Protein |
denotes |
IL-12, IL-4 |
| T6294 |
15991-15996 |
Protein |
denotes |
IL-10 |
| T6295 |
16001-16007 |
Protein |
denotes |
TGFβ 1 |
| T6303 |
16016-16023 |
Positive_regulation |
denotes |
induced |
| T6302 |
16016-16023 |
Positive_regulation |
denotes |
induced |
| T6301 |
16016-16023 |
Positive_regulation |
denotes |
induced |
| T6300 |
16016-16023 |
Positive_regulation |
denotes |
induced |
| T8707 |
16202-16206 |
Positive_regulation |
denotes |
Role |
| T8706 |
16202-16206 |
Positive_regulation |
denotes |
Role |
| T8699 |
16210-16214 |
Protein |
denotes |
NFκB |
| T8700 |
16216-16222 |
Protein |
denotes |
NFIL-6 |
| T8701 |
16227-16231 |
Protein |
denotes |
NFAT |
| T8704 |
16232-16239 |
Binding |
denotes |
binding |
| T8703 |
16232-16239 |
Binding |
denotes |
binding |
| T8708 |
16282-16296 |
Positive_regulation |
denotes |
TSST-1-induced |
| T8702 |
16297-16303 |
Protein |
denotes |
IL-1RA |
| T8705 |
16304-16314 |
Gene_expression |
denotes |
expression |
| T8709 |
16363-16367 |
Protein |
denotes |
NFκB |
| T8710 |
16369-16375 |
Protein |
denotes |
NFIL-6 |
| T8711 |
16380-16390 |
Protein |
denotes |
NFAT sites |
| T8712 |
16399-16403 |
Protein |
denotes |
TNFα |
| T8713 |
16405-16417 |
Protein |
denotes |
IL-6 or IFNγ |
| T8715 |
16482-16486 |
Binding |
denotes |
bind |
| T8714 |
16503-16518 |
Protein |
denotes |
IL-1RA promoter |
| T8716 |
16715-16732 |
Protein |
denotes |
LPS responsive κB |
| T8719 |
16981-16988 |
Binding |
denotes |
binding |
| T8717 |
17000-17006 |
Protein |
denotes |
TSST-1 |
| T8718 |
17096-17102 |
Protein |
denotes |
TSST-1 |
| T8721 |
17328-17335 |
Binding |
denotes |
Binding |
| T8720 |
17345-17347 |
Protein |
denotes |
κB |
| T8722 |
17405-17413 |
Positive_regulation |
denotes |
elevated |
| T8723 |
17644-17655 |
Protein |
denotes |
NFIL-6 site |
| T8725 |
17705-17718 |
Positive_regulation |
denotes |
up-regulation |
| T8724 |
17722-17729 |
Binding |
denotes |
binding |
| T8728 |
17850-17859 |
Positive_regulation |
denotes |
increased |
| T8727 |
17860-17867 |
Binding |
denotes |
binding |
| T8726 |
17875-17886 |
Protein |
denotes |
NFIL-6 site |
| T8729 |
17991-17999 |
Protein |
denotes |
NFATP2/3 |
| T8731 |
18109-18117 |
Positive_regulation |
denotes |
increase |
| T8730 |
18121-18128 |
Binding |
denotes |
binding |
| T23902 |
18554-18561 |
Binding |
denotes |
binding |
| T23901 |
18554-18561 |
Binding |
denotes |
binding |
| T23900 |
18554-18561 |
Binding |
denotes |
binding |
| T23898 |
18571-18581 |
Protein |
denotes |
NFκB3 site |
| T23899 |
18589-18604 |
Protein |
denotes |
IL-1RA promoter |
| T24239 |
18953-18968 |
Protein |
denotes |
IL-1RA promoter |
| T24243 |
19246-19254 |
Positive_regulation |
denotes |
elevated |
| T24240 |
19255-19263 |
Protein |
denotes |
NFAT-DNA |
| T24242 |
19264-19271 |
Binding |
denotes |
binding |
| T24241 |
19300-19315 |
Protein |
denotes |
IL-1RA promoter |
| T9936 |
19774-19779 |
Protein |
denotes |
IL-1β |
| T9937 |
19784-19790 |
Protein |
denotes |
IL-1RA |
| T9938 |
19893-19898 |
Protein |
denotes |
IL-1β |
| T9939 |
19899-19905 |
Protein |
denotes |
IL-1RA |
| T9943 |
20005-20015 |
Positive_regulation |
denotes |
generating |
| T9942 |
20005-20015 |
Positive_regulation |
denotes |
generating |
| T9940 |
20021-20026 |
Protein |
denotes |
IL-1β |
| T9941 |
20032-20038 |
Protein |
denotes |
IL-1RA |
| T9944 |
20180-20185 |
Protein |
denotes |
IL-1β |
| T9945 |
20186-20192 |
Protein |
denotes |
IL-1RA |
| T9946 |
20272-20278 |
Protein |
denotes |
TSST-1 |
| T9950 |
20497-20507 |
Gene_expression |
denotes |
production |
| T9949 |
20497-20507 |
Gene_expression |
denotes |
production |
| T9947 |
20511-20517 |
Protein |
denotes |
IL-1RA |
| T9948 |
20526-20531 |
Protein |
denotes |
IL-1β |
| T9955 |
20621-20629 |
Negative_regulation |
denotes |
decrease |
| T9951 |
20637-20659 |
Protein |
denotes |
IL-1 dependent release |
| T9952 |
20663-20667 |
Protein |
denotes |
IL-2 |
| T9953 |
20730-20736 |
Protein |
denotes |
TSST-1 |
| T9954 |
20740-20754 |
Protein |
denotes |
GP/TSST-1 calc |
| T24871 |
20811-20820 |
Negative_regulation |
denotes |
Decreased |
| T24869 |
20821-20833 |
Protein |
denotes |
IL-1β/IL-1RA |
| T24870 |
20879-20885 |
Protein |
denotes |
TSST-1 |
| T24872 |
20913-20925 |
Protein |
denotes |
IL-1β/IL-1RA |
| T24876 |
21080-21090 |
Positive_regulation |
denotes |
generating |
| T24875 |
21080-21090 |
Positive_regulation |
denotes |
generating |
| T24873 |
21096-21101 |
Protein |
denotes |
IL-1β |
| T24874 |
21107-21113 |
Protein |
denotes |
IL-1RA |
| T24880 |
21201-21212 |
Regulation |
denotes |
alterations |
| T24879 |
21201-21212 |
Regulation |
denotes |
alterations |
| T24877 |
21220-21225 |
Protein |
denotes |
IL-1β |
| T24878 |
21226-21232 |
Protein |
denotes |
IL-1RA |
| T24881 |
21266-21272 |
Protein |
denotes |
TSST-1 |
| T24882 |
21276-21290 |
Protein |
denotes |
GP/TSST-1 calc |
| T24883 |
21292-21306 |
Protein |
denotes |
vs GP + TSST-1 |
| T24887 |
21450-21460 |
Gene_expression |
denotes |
production |
| T24886 |
21450-21460 |
Gene_expression |
denotes |
production |
| T24884 |
21464-21470 |
Protein |
denotes |
IL-1RA |
| T24885 |
21479-21484 |
Protein |
denotes |
IL-1β |
| T10822 |
21583-21590 |
Negative_regulation |
denotes |
reduced |
| T10821 |
21591-21597 |
Protein |
denotes |
IL-1RA |
| T10823 |
21704-21719 |
Protein |
denotes |
IL-1RA promoter |
| T10827 |
21724-21732 |
Positive_regulation |
denotes |
relevant |
| T10826 |
21741-21750 |
Positive_regulation |
denotes |
induction |
| T10824 |
21754-21760 |
Protein |
denotes |
IL-1RA |
| T10825 |
21764-21766 |
Protein |
denotes |
GP |
| T10835 |
21784-21794 |
Negative_regulation |
denotes |
inhibition |
| T10834 |
21784-21794 |
Negative_regulation |
denotes |
inhibition |
| T10828 |
21798-21802 |
Protein |
denotes |
NFκB |
| T10829 |
21807-21824 |
Protein |
denotes |
CAPE [35] and CyA |
| T10830 |
21826-21838 |
Protein |
denotes |
NFAT via CyA |
| T10831 |
21843-21849 |
Protein |
denotes |
NFIL-6 |
| T10837 |
21994-22003 |
Negative_regulation |
denotes |
reduction |
| T10836 |
21994-22003 |
Negative_regulation |
denotes |
reduction |
| T10832 |
22007-22018 |
Protein |
denotes |
IL-1RA mRNA |
| T10833 |
22023-22037 |
Protein |
denotes |
IL-1RA protein |
| T10838 |
22238-22242 |
Protein |
denotes |
NFκB |
| T10839 |
22247-22267 |
Protein |
denotes |
NFIL-6 binding sites |
| T10840 |
22311-22325 |
Protein |
denotes |
highest IL-1RA |
| T10843 |
22448-22456 |
Negative_regulation |
denotes |
decrease |
| T10841 |
22460-22466 |
Protein |
denotes |
IL-1RA |
| T10842 |
22528-22531 |
Protein |
denotes |
Fig |
| T10844 |
22572-22586 |
Protein |
denotes |
IL-1RA protein |
| T10848 |
22587-22593 |
Gene_expression |
denotes |
levels |
| T10847 |
22587-22593 |
Gene_expression |
denotes |
levels |
| T10845 |
22608-22610 |
Protein |
denotes |
GP |
| T10846 |
22624-22627 |
Protein |
denotes |
Fig |
| T10849 |
22653-22657 |
Protein |
denotes |
NFκB |
| T10851 |
22658-22668 |
Negative_regulation |
denotes |
inhibition |
| T10854 |
22686-22696 |
Positive_regulation |
denotes |
pronounced |
| T10852 |
22704-22711 |
Binding |
denotes |
binding |
| T10855 |
22780-22789 |
Negative_regulation |
denotes |
decreased |
| T10850 |
22790-22796 |
Protein |
denotes |
IL-1RA |
| T10853 |
22797-22804 |
Localization |
denotes |
release |
| T25553 |
22816-22826 |
Negative_regulation |
denotes |
Inhibition |
| T25552 |
22816-22826 |
Negative_regulation |
denotes |
Inhibition |
| T25548 |
22841-22845 |
Protein |
denotes |
NFκB |
| T25549 |
22847-22851 |
Protein |
denotes |
NFAT |
| T25550 |
22856-22862 |
Protein |
denotes |
NFIL-6 |
| T25556 |
22867-22874 |
Binding |
denotes |
binding |
| T25555 |
22867-22874 |
Binding |
denotes |
binding |
| T25554 |
22867-22874 |
Binding |
denotes |
binding |
| T25551 |
22882-22897 |
Protein |
denotes |
IL-1RA promoter |
| T25557 |
23158-23171 |
Protein |
denotes |
NFATP2/3 site |
| T25563 |
23316-23326 |
Negative_regulation |
denotes |
Inhibition |
| T25558 |
23330-23334 |
Protein |
denotes |
NFκB |
| T25559 |
23336-23340 |
Protein |
denotes |
NFAT |
| T25560 |
23345-23351 |
Protein |
denotes |
NFIL-6 |
| T25564 |
23364-23373 |
Negative_regulation |
denotes |
decreased |
| T25561 |
23374-23385 |
Protein |
denotes |
IL-1RA mRNA |
| T25562 |
23425-23427 |
Protein |
denotes |
GP |
| T25565 |
23429-23434 |
Protein |
denotes |
GAPDH |
| T25570 |
23499-23509 |
Negative_regulation |
denotes |
Inhibition |
| T25566 |
23513-23517 |
Protein |
denotes |
NFκB |
| T25567 |
23519-23523 |
Protein |
denotes |
NFAT |
| T25568 |
23528-23534 |
Protein |
denotes |
NFIL-6 |
| T25573 |
23549-23556 |
Negative_regulation |
denotes |
reduced |
| T25572 |
23549-23556 |
Negative_regulation |
denotes |
reduced |
| T25571 |
23561-23571 |
Gene_expression |
denotes |
production |
| T25569 |
23575-23581 |
Protein |
denotes |
IL-1RA |
| T11939 |
23891-23895 |
Protein |
denotes |
NFκB |
| T11940 |
23900-23904 |
Protein |
denotes |
PI3K |
| T11949 |
24263-24270 |
Positive_regulation |
denotes |
induced |
| T11948 |
24263-24270 |
Positive_regulation |
denotes |
induced |
| T11947 |
24263-24270 |
Positive_regulation |
denotes |
induced |
| T11946 |
24271-24278 |
Binding |
denotes |
binding |
| T11945 |
24271-24278 |
Binding |
denotes |
binding |
| T11944 |
24271-24278 |
Binding |
denotes |
binding |
| T11941 |
24282-24286 |
Protein |
denotes |
NFκB |
| T11942 |
24289-24295 |
Protein |
denotes |
NFIL-6 |
| T11943 |
24301-24305 |
Protein |
denotes |
NFAT |
| T11950 |
24383-24387 |
Protein |
denotes |
NFAT |
| T11951 |
24388-24395 |
Binding |
denotes |
binding |
| T11952 |
24659-24663 |
Protein |
denotes |
IL-8 |
| T11953 |
24668-24674 |
Protein |
denotes |
IL-1RA |
| T12233 |
24676-24683 |
Protein |
denotes |
Fig. 3B |
| T12238 |
24920-24927 |
Binding |
denotes |
binding |
| T12234 |
24931-24939 |
Protein |
denotes |
NFκB p65 |
| T12235 |
24966-24969 |
Protein |
denotes |
p50 |
| T12236 |
24975-24977 |
Protein |
denotes |
κB |
| T12237 |
25000-25013 |
Protein |
denotes |
IL-8 promoter |
| T12243 |
25082-25091 |
Positive_regulation |
denotes |
induction |
| T12239 |
25095-25099 |
Protein |
denotes |
IL-8 |
| T12241 |
25100-25113 |
Transcription |
denotes |
transcription |
| T12242 |
25127-25137 |
Positive_regulation |
denotes |
activation |
| T12240 |
25145-25166 |
Protein |
denotes |
NFκB p65/65 homodimer |
| T12248 |
25335-25349 |
Positive_regulation |
denotes |
transactivated |
| T12244 |
25350-25358 |
Protein |
denotes |
NFκB p65 |
| T12245 |
25363-25369 |
Protein |
denotes |
NFIL-6 |
| T12246 |
25381-25387 |
Protein |
denotes |
NFATc2 |
| T12250 |
25394-25401 |
Binding |
denotes |
binding |
| T12249 |
25394-25401 |
Binding |
denotes |
binding |
| T12247 |
25409-25420 |
Protein |
denotes |
IL-8κB site |
| T12251 |
25451-25457 |
Protein |
denotes |
IL-8κB |
| T12252 |
25499-25520 |
Protein |
denotes |
p65 binding half site |
| T12253 |
25547-25559 |
Protein |
denotes |
κB half site |
| T12254 |
25574-25578 |
Protein |
denotes |
TNFα |
| T12255 |
25583-25588 |
Protein |
denotes |
IL-1β |
| T12260 |
25598-25608 |
Positive_regulation |
denotes |
supporting |
| T12259 |
25621-25631 |
Regulation |
denotes |
regulating |
| T12256 |
25632-25636 |
Protein |
denotes |
NFκB |
| T12258 |
25637-25644 |
Binding |
denotes |
binding |
| T12257 |
25739-25747 |
Protein |
denotes |
κB motif |
| T12263 |
25804-25810 |
Positive_regulation |
denotes |
induce |
| T12261 |
25811-25816 |
Protein |
denotes |
IL-1β |
| T12264 |
25834-25841 |
Positive_regulation |
denotes |
induced |
| T12262 |
25842-25848 |
Protein |
denotes |
IL-1RA |
| T12265 |
25923-25938 |
Protein |
denotes |
IL-1RA promoter |
| T12269 |
25939-25942 |
Entity |
denotes |
[34 |
| T12266 |
25995-26000 |
Protein |
denotes |
NFκB3 |
| T12267 |
26034-26038 |
Protein |
denotes |
NFκB |
| T12268 |
26079-26091 |
Protein |
denotes |
NFκB2/3 site |
| T12270 |
26181-26183 |
Protein |
denotes |
GP |
| T12283 |
26184-26189 |
Positive_regulation |
denotes |
leads |
| T12278 |
26193-26203 |
Gene_expression |
denotes |
production |
| T12271 |
26207-26213 |
Protein |
denotes |
IL-1RA |
| T12285 |
26228-26237 |
Positive_regulation |
denotes |
induction |
| T12284 |
26228-26237 |
Positive_regulation |
denotes |
induction |
| T12279 |
26228-26237 |
Positive_regulation |
denotes |
induction |
| T12272 |
26241-26249 |
Protein |
denotes |
NFATP2/3 |
| T12273 |
26254-26264 |
Protein |
denotes |
NFIL-6 DNA |
| T12281 |
26265-26272 |
Binding |
denotes |
binding |
| T12280 |
26265-26272 |
Binding |
denotes |
binding |
| T12282 |
26289-26292 |
Regulation |
denotes |
due |
| T12274 |
26355-26386 |
Protein |
denotes |
activated transcription factors |
| T12275 |
26388-26392 |
Protein |
denotes |
NFAT |
| T12276 |
26406-26416 |
Protein |
denotes |
IFNγ, IL-6 |
| T12277 |
26421-26436 |
Protein |
denotes |
IL-1RA promoter |
| T12295 |
26455-26463 |
Negative_regulation |
denotes |
decrease |
| T12294 |
26455-26463 |
Negative_regulation |
denotes |
decrease |
| T12293 |
26455-26463 |
Negative_regulation |
denotes |
decrease |
| T12286 |
26467-26471 |
Protein |
denotes |
NFκB |
| T12287 |
26473-26477 |
Protein |
denotes |
NFAT |
| T12288 |
26482-26488 |
Protein |
denotes |
NFIL-6 |
| T12289 |
26513-26528 |
Protein |
denotes |
IL-1RA promoter |
| T12290 |
26543-26554 |
Protein |
denotes |
IL-1RA mRNA |
| T12297 |
26695-26704 |
Positive_regulation |
denotes |
induction |
| T12296 |
26695-26704 |
Positive_regulation |
denotes |
induction |
| T12291 |
26708-26714 |
Protein |
denotes |
IL-1RA |
| T12292 |
26716-26719 |
Protein |
denotes |
Fig |
| T12300 |
26925-26932 |
Gene_expression |
denotes |
produce |
| T12301 |
26925-26932 |
Gene_expression |
denotes |
produce |
| T12298 |
26933-26937 |
Protein |
denotes |
IL-8 |
| T12299 |
26946-26952 |
Protein |
denotes |
IL-1RA |
| T12302 |
27222-27242 |
Protein |
denotes |
Toll-like receptor 4 |
| T12303 |
27276-27280 |
Protein |
denotes |
NFκB |
| T12412 |
27301-27311 |
Gene_expression |
denotes |
expression |
| T12304 |
27347-27356 |
Protein |
denotes |
TNFα [43] |
| T12413 |
27358-27382 |
Protein |
denotes |
A bacterial superantigen |
| T12414 |
27388-27394 |
Protein |
denotes |
TSST-1 |
| T12420 |
27408-27415 |
Binding |
denotes |
binding |
| T12415 |
27419-27435 |
Protein |
denotes |
MHC-II molecules |
| T12416 |
27457-27507 |
Protein |
denotes |
T cell receptor, leading to release of mainly IFNγ |
| T12417 |
27512-27516 |
Protein |
denotes |
TNFα |
| T12418 |
27539-27543 |
Protein |
denotes |
PI3K |
| T12419 |
27548-27551 |
Protein |
denotes |
p38 |
| T12424 |
27570-27576 |
Negative_regulation |
denotes |
kinase |
| T12423 |
27570-27576 |
Negative_regulation |
denotes |
kinase |
| T12422 |
27570-27576 |
Negative_regulation |
denotes |
kinase |
| T12421 |
27570-27576 |
Negative_regulation |
denotes |
kinase |
| T12426 |
27612-27621 |
Positive_regulation |
denotes |
induction |
| T12425 |
27651-27655 |
Protein |
denotes |
IL-8 |
| T26190 |
27870-27885 |
Protein |
denotes |
IL-1RA promoter |
| T12436 |
28353-28360 |
Regulation |
denotes |
altered |
| T12435 |
28353-28360 |
Regulation |
denotes |
altered |
| T12427 |
28380-28385 |
Protein |
denotes |
IL-1β |
| T12428 |
28386-28392 |
Protein |
denotes |
IL-1RA |
| T12433 |
28447-28462 |
Negative_regulation |
denotes |
down-regulation |
| T12432 |
28447-28462 |
Negative_regulation |
denotes |
down-regulation |
| T12429 |
28466-28471 |
Protein |
denotes |
IL-1β |
| T12430 |
28476-28480 |
Protein |
denotes |
IL-6 |
| T12434 |
28523-28536 |
Positive_regulation |
denotes |
up-regulation |
| T12431 |
28540-28546 |
Protein |
denotes |
IL-1RA |
| T12437 |
28617-28623 |
Protein |
denotes |
TSST-1 |
| T12438 |
28643-28647 |
Protein |
denotes |
NFκB |
| T12439 |
28649-28655 |
Protein |
denotes |
NFIL-6 |
| T12440 |
28660-28664 |
Protein |
denotes |
NFAT |
| T12441 |
28713-28717 |
Protein |
denotes |
IL-8 |
| T12442 |
28722-28737 |
Protein |
denotes |
IL-1RA promoter |
| T12443 |
28753-28757 |
Protein |
denotes |
TNFα |
| T12444 |
28759-28764 |
Protein |
denotes |
IL-1β |
| T12445 |
28766-28770 |
Protein |
denotes |
IL-6 |
| T12446 |
28774-28787 |
Protein |
denotes |
IFNγ promoter |
| T12450 |
28835-28842 |
Binding |
denotes |
binding |
| T12449 |
28835-28842 |
Binding |
denotes |
binding |
| T12447 |
28846-28850 |
Protein |
denotes |
NFκB |
| T12448 |
28869-28882 |
Protein |
denotes |
TNFα promoter |
| T12451 |
29048-29058 |
Protein |
denotes |
NFκB sites |
| T12452 |
29068-29083 |
Protein |
denotes |
IL-1RA promoter |
| T12455 |
29120-29127 |
Binding |
denotes |
binding |
| T12453 |
29135-29140 |
Protein |
denotes |
NFκB3 |
| T12454 |
29183-29187 |
Protein |
denotes |
NFκB |
| T12456 |
29216-29225 |
Positive_regulation |
denotes |
increased |
| T12469 |
29269-29284 |
Negative_regulation |
denotes |
down-regulation |
| T12468 |
29269-29284 |
Negative_regulation |
denotes |
down-regulation |
| T12457 |
29305-29311 |
Protein |
denotes |
TSST-1 |
| T12471 |
29312-29319 |
Positive_regulation |
denotes |
induced |
| T12470 |
29312-29319 |
Positive_regulation |
denotes |
induced |
| T12458 |
29320-29324 |
Protein |
denotes |
NFκB |
| T12464 |
29325-29332 |
Binding |
denotes |
binding |
| T12463 |
29325-29332 |
Binding |
denotes |
binding |
| T12459 |
29349-29362 |
Protein |
denotes |
TNFα promoter |
| T12467 |
29377-29390 |
Positive_regulation |
denotes |
up-regulation |
| T12466 |
29377-29390 |
Positive_regulation |
denotes |
up-regulation |
| T12465 |
29377-29390 |
Positive_regulation |
denotes |
up-regulation |
| T12460 |
29394-29399 |
Protein |
denotes |
NFκB3 |
| T12461 |
29404-29408 |
Protein |
denotes |
NFκB |
| T12462 |
29432-29447 |
Protein |
denotes |
IL-1RA promoter |
| T12472 |
29528-29541 |
Protein |
denotes |
NFκB subunits |
| T12473 |
29603-29607 |
Protein |
denotes |
NFκB |
| T12474 |
29634-29638 |
Protein |
denotes |
TNFα |
| T12475 |
29647-29662 |
Protein |
denotes |
IL-1RA promoter |
| T12476 |
29668-29673 |
Protein |
denotes |
NFκB3 |
| T12477 |
29678-29690 |
Protein |
denotes |
IL-1RA motif |
| T12478 |
29753-29763 |
Protein |
denotes |
TNFα motif |
| T12479 |
29863-29867 |
Protein |
denotes |
NFκB |
| T12480 |
29948-29963 |
Protein |
denotes |
IL-1RA promoter |
| T12481 |
30039-30051 |
Protein |
denotes |
NFκB2/3 site |
| T12487 |
30352-30360 |
Positive_regulation |
denotes |
increase |
| T12486 |
30379-30386 |
Binding |
denotes |
binding |
| T12482 |
30398-30403 |
Protein |
denotes |
NFκB3 |
| T12483 |
30408-30412 |
Protein |
denotes |
NFκB |
| T12484 |
30433-30449 |
Protein |
denotes |
NFIL-6 site [32] |
| T12485 |
30474-30487 |
Protein |
denotes |
NFATP2/3 site |
| T12489 |
30652-30660 |
Negative_regulation |
denotes |
decrease |
| T12488 |
30668-30680 |
Protein |
denotes |
IL-1β/IL-1RA |
| T12490 |
30793-30799 |
Protein |
denotes |
IL-1RA |
| T12491 |
30805-30810 |
Protein |
denotes |
IL-1β |
| T12492 |
30885-30897 |
Protein |
denotes |
IL-1β/IL-1RA |
| T12493 |
30993-30998 |
Protein |
denotes |
IL-1β |
| T12494 |
31014-31025 |
Negative_regulation |
denotes |
inactivated |
| T12495 |
31080-31084 |
Protein |
denotes |
IL-1 |
| T12496 |
31362-31368 |
Protein |
denotes |
TSST-1 |
| T12497 |
31395-31399 |
Protein |
denotes |
PI3K |
| T12498 |
31552-31556 |
Protein |
denotes |
PI3K |
| T12504 |
31577-31585 |
Regulation |
denotes |
controls |
| T12503 |
31577-31585 |
Regulation |
denotes |
controls |
| T12499 |
31586-31593 |
Protein |
denotes |
sIL-1RA |
| T12500 |
31602-31607 |
Protein |
denotes |
IL-1β |
| T12502 |
31608-31618 |
Gene_expression |
denotes |
production |
| T12501 |
31608-31618 |
Gene_expression |
denotes |
production |
| T12505 |
31639-31643 |
Protein |
denotes |
PI3K |
| T12507 |
31684-31694 |
Positive_regulation |
denotes |
activation |
| T12506 |
31698-31702 |
Protein |
denotes |
NFAT |
| T12511 |
31720-31730 |
Positive_regulation |
denotes |
Activation |
| T12508 |
31734-31738 |
Protein |
denotes |
NFκB |
| T12509 |
31843-31845 |
Protein |
denotes |
GP |
| T12510 |
31847-31851 |
Protein |
denotes |
PI3K |
| T12512 |
31983-31986 |
Protein |
denotes |
PRR |
| T12513 |
31988-31991 |
Protein |
denotes |
LPS |
| T12514 |
31996-32009 |
Protein |
denotes |
peptidoglycan |
| T12516 |
32010-32019 |
Positive_regulation |
denotes |
activated |
| T12517 |
32010-32019 |
Positive_regulation |
denotes |
activated |
| T12515 |
32024-32030 |
Protein |
denotes |
IL-1RA |
| T17273 |
32377-32383 |
Protein |
denotes |
TSST-1 |
| T17277 |
32595-32602 |
Binding |
denotes |
binding |
| T17276 |
32595-32602 |
Binding |
denotes |
binding |
| T17274 |
32654-32669 |
Protein |
denotes |
IL-1RA promoter |
| T17275 |
32671-32674 |
Protein |
denotes |
Fig |
| T17279 |
32693-32702 |
Regulation |
denotes |
regulated |
| T17278 |
32693-32702 |
Regulation |
denotes |
regulated |
| T17280 |
32860-32866 |
Protein |
denotes |
glucan |
| T17951 |
34695-34697 |
Protein |
denotes |
GP |
| T17952 |
34702-34708 |
Protein |
denotes |
TSST-1 |
| T18498 |
34868-34872 |
Protein |
denotes |
TNFα |
| T18499 |
34874-34903 |
Protein |
denotes |
IL-8, IFNγ and IL-6 promoters |
| T18500 |
35135-35138 |
Protein |
denotes |
Kit |
| T18501 |
35140-35143 |
Protein |
denotes |
PNK |
| T18502 |
35344-35351 |
Protein |
denotes |
P2 site |
| T18503 |
35359-35363 |
Protein |
denotes |
IFNγ |
| T18508 |
35364-35372 |
Entity |
denotes |
promoter |
| T18504 |
35389-35409 |
Protein |
denotes |
κ consensus sequence |
| T18505 |
35417-35430 |
Protein |
denotes |
TNFα promoter |
| T18512 |
35501-35508 |
Positive_regulation |
denotes |
crucial |
| T18511 |
35501-35508 |
Positive_regulation |
denotes |
crucial |
| T18510 |
35517-35524 |
Binding |
denotes |
binding |
| T18509 |
35517-35524 |
Binding |
denotes |
binding |
| T18506 |
35528-35532 |
Protein |
denotes |
NFAT |
| T18507 |
35537-35550 |
Protein |
denotes |
NFκB proteins |
| T18808 |
36375-36379 |
Protein |
denotes |
NFκB |
| T18809 |
36506-36511 |
Protein |
denotes |
Oct-1 |
| T18810 |
36587-36594 |
Binding |
denotes |
binding |
| T19220 |
36677-36681 |
Protein |
denotes |
NFκB |
| T19221 |
36686-36690 |
Protein |
denotes |
NFAT |
| T19222 |
36939-36947 |
Protein |
denotes |
NFκB p52 |
| T19223 |
37063-37076 |
Protein |
denotes |
anti-NFκB p50 |
| T19224 |
37096-37100 |
Protein |
denotes |
NFκB |
| T19225 |
37122-37126 |
Protein |
denotes |
NFκB |
| T19226 |
37154-37179 |
Protein |
denotes |
polyclonal IgG1 antiserum |
| T19227 |
37181-37191 |
Protein |
denotes |
anti-c-rel |
| T19228 |
37193-37197 |
Protein |
denotes |
N466 |
| T19229 |
37267-37296 |
Protein |
denotes |
goat polyclonal IgG1 antisera |
| T19230 |
37350-37353 |
Protein |
denotes |
IgG |
| T19254 |
37397-37400 |
Protein |
denotes |
IgG |
| T19255 |
37493-37496 |
Protein |
denotes |
Rad |
| T19256 |
37688-37708 |
Protein |
denotes |
alkaline phosphatase |
| T19775 |
38055-38059 |
Protein |
denotes |
TNFα |
| T19776 |
38061-38065 |
Protein |
denotes |
IL-1 |
| T19777 |
38070-38074 |
Protein |
denotes |
IL-6 |
| T19778 |
38145-38151 |
Protein |
denotes |
IL-1RA |
| T19779 |
38156-38160 |
Protein |
denotes |
IL-8 |
| T19780 |
38228-38234 |
Protein |
denotes |
TGFβ 1 |
| T19781 |
38298-38302 |
Protein |
denotes |
IL-2 |
| T19782 |
38342-38346 |
Protein |
denotes |
IL-1 |
| T20301 |
39360-39366 |
Protein |
denotes |
NFIL-6 |
| T20302 |
39368-39383 |
Protein |
denotes |
TTA CAA CAG TGG |
| T20303 |
39384-39399 |
Protein |
denotes |
ATT GCG ACA CTT |
| T20304 |
39400-39407 |
Protein |
denotes |
AGT GGG |
| T20305 |
39413-39421 |
Protein |
denotes |
NFATP2/3 |
| T20306 |
39423-39430 |
Protein |
denotes |
GGC GCA |
| T20307 |
39435-39454 |
Protein |
denotes |
AAG GTA AAA TAT TTA |
| T20308 |
39455-39462 |
Protein |
denotes |
CTA TCT |
| T20309 |
39489-39504 |
Protein |
denotes |
IL-1RA promoter |
| T20310 |
39614-39621 |
Protein |
denotes |
Reactin |
| T20311 |
39671-39677 |
Protein |
denotes |
IL-1RA |
| T20312 |
39682-39699 |
Protein |
denotes |
GAPDH transcripts |
| T20313 |
39811-39817 |
Protein |
denotes |
IL-1RA |
| T20314 |
39890-39895 |
Protein |
denotes |
GAPDH |
| T20315 |
39932-39946 |
Protein |
denotes |
IL-1RA protein |
| T21010 |
40525-40528 |
Protein |
denotes |
Fig |
| R1065 |
T1990 |
T1993 |
themeOf |
IL-6,secretion |
| R1066 |
T1991 |
T1994 |
themeOf |
TNFα,secretion |
| R1067 |
T1995 |
T1996 |
themeOf |
IL-1,production |
| R1068 |
T1997 |
T1998 |
themeOf |
IL-8,produce |
| R1069 |
T1999 |
T2002 |
themeOf |
NFκB,inhibition |
| R1070 |
T2004 |
T2014 |
themeOf |
TNFα,production |
| R1071 |
T2005 |
T2015 |
themeOf |
IL-1β,production |
| R1072 |
T2022 |
T2023 |
themeOf |
IL-1RA promoter,binding |
| R1073 |
T1976 |
T1979 |
themeOf |
Dectin-1,binding |
| R1074 |
T1977 |
T1980 |
themeOf |
TNFα,production |
| R1075 |
T1978 |
T1981 |
themeOf |
Toll-like receptor 2,production |
| R1076 |
T1979 |
T1982 |
causeOf |
binding,resulted |
| R1077 |
T1979 |
T1983 |
causeOf |
binding,resulted |
| R1078 |
T1980 |
T1982 |
themeOf |
production,resulted |
| R1079 |
T1981 |
T1983 |
themeOf |
production,resulted |
| R1080 |
T1984 |
T1986 |
themeOf |
NFκB,activate |
| R1081 |
T1985 |
T1987 |
themeOf |
NFIL-6,activate |
| R1082 |
T1989 |
T1992 |
themeOf |
IL-1,secretion |
| R1083 |
T2024 |
T2028 |
partOf |
IL-1RA promoter,LRE-1 |
| R1084 |
T2027 |
T2028 |
partOf |
NFIL-6 sites,LRE-1 |
| R1085 |
T2025 |
T2028 |
partOf |
NFκB,LRE-1 |
| R11628 |
T17274 |
T17276 |
themeOf |
IL-1RA promoter,binding |
| R11629 |
T17274 |
T17278 |
themeOf |
IL-1RA promoter,regulated |
| R11630 |
T17275 |
T17277 |
themeOf |
Fig,binding |
| R11631 |
T17275 |
T17279 |
themeOf |
Fig,regulated |
| R12657 |
T18502 |
T18508 |
partOf |
P2 site,promoter |
| R12658 |
T18503 |
T18508 |
partOf |
IFNγ,promoter |
| R12659 |
T18506 |
T18509 |
themeOf |
NFAT,binding |
| R12660 |
T18507 |
T18510 |
themeOf |
NFκB proteins,binding |
| R12661 |
T18509 |
T18511 |
themeOf |
binding,crucial |
| R12662 |
T18510 |
T18512 |
themeOf |
binding,crucial |
| R12865 |
T18809 |
T18810 |
themeOf |
Oct-1,binding |
| R14762 |
T21528 |
T21531 |
themeOf |
NFAT,binding |
| R14763 |
T21529 |
T21532 |
themeOf |
NFκB,binding |
| R14764 |
T21530 |
T21533 |
themeOf |
NFIL-6,binding |
| R14765 |
T21548 |
T21551 |
themeOf |
NFκB,binding |
| R15326 |
T22409 |
T22414 |
themeOf |
NFκB,binding |
| R15327 |
T22409 |
T22419 |
themeOf |
NFκB,binding |
| R15328 |
T22410 |
T22415 |
themeOf |
p65,binding |
| R15329 |
T22410 |
T22419 |
themeOf |
p65,binding |
| R15330 |
T22411 |
T22416 |
themeOf |
p50,binding |
| R15331 |
T22412 |
T22417 |
themeOf |
NFATc2,binding |
| R15332 |
T22413 |
T22418 |
themeOf |
c1,binding |
| R15333 |
T22425 |
T22433 |
themeOf |
NFκB p50,positive |
| R15334 |
T22426 |
T22434 |
themeOf |
p65,positive |
| R15335 |
T22427 |
T22435 |
themeOf |
for NFATc1,positive |
| R15336 |
T22429 |
T22436 |
themeOf |
NFκB p65,positive |
| R15337 |
T22430 |
T22437 |
themeOf |
p50,positive |
| R15338 |
T22431 |
T22438 |
themeOf |
NFAT c2,positive |
| R15339 |
T22432 |
T22439 |
themeOf |
c1,positive |
| R15652 |
T23019 |
T23021 |
themeOf |
IL-1β,down-regulated |
| R15653 |
T23022 |
T23023 |
themeOf |
IL-1β,production |
| R15654 |
T23024 |
T23026 |
themeOf |
IL-1β,production |
| R15655 |
T23026 |
T23027 |
themeOf |
production,reduction |
| R15656 |
T23031 |
T23032 |
themeOf |
IL-1RA,production |
| R16256 |
T23898 |
T23900 |
themeOf |
NFκB3 site,binding |
| R16257 |
T23898 |
T23902 |
themeOf |
NFκB3 site,binding |
| R16258 |
T23899 |
T23901 |
themeOf |
IL-1RA promoter,binding |
| R16259 |
T23899 |
T23902 |
themeOf |
IL-1RA promoter,binding |
| R16474 |
T24240 |
T24242 |
themeOf |
NFAT-DNA,binding |
| R16475 |
T24242 |
T24243 |
themeOf |
binding,elevated |
| R16885 |
T24869 |
T24871 |
themeOf |
IL-1β/IL-1RA,Decreased |
| R16886 |
T24873 |
T24875 |
themeOf |
IL-1β,generating |
| R16887 |
T24874 |
T24876 |
themeOf |
IL-1RA,generating |
| R16888 |
T24877 |
T24879 |
themeOf |
IL-1β,alterations |
| R16889 |
T24878 |
T24880 |
themeOf |
IL-1RA,alterations |
| R16890 |
T24884 |
T24886 |
themeOf |
IL-1RA,production |
| R16891 |
T24885 |
T24887 |
themeOf |
IL-1β,production |
| R17297 |
T25548 |
T25552 |
themeOf |
NFκB,Inhibition |
| R17298 |
T25548 |
T25555 |
themeOf |
NFκB,binding |
| R17299 |
T25549 |
T25553 |
themeOf |
NFAT,Inhibition |
| R17300 |
T25549 |
T25556 |
themeOf |
NFAT,binding |
| R17301 |
T25551 |
T25554 |
themeOf |
IL-1RA promoter,binding |
| R17302 |
T25551 |
T25555 |
themeOf |
IL-1RA promoter,binding |
| R17303 |
T25551 |
T25556 |
themeOf |
IL-1RA promoter,binding |
| R17304 |
T25558 |
T25563 |
themeOf |
NFκB,Inhibition |
| R17305 |
T25561 |
T25564 |
themeOf |
IL-1RA mRNA,decreased |
| R17306 |
T25566 |
T25570 |
themeOf |
NFκB,Inhibition |
| R17307 |
T25567 |
T25572 |
causeOf |
NFAT,reduced |
| R17308 |
T25568 |
T25573 |
causeOf |
NFIL-6,reduced |
| R17309 |
T25569 |
T25571 |
themeOf |
IL-1RA,production |
| R17310 |
T25571 |
T25572 |
themeOf |
production,reduced |
| R17311 |
T25571 |
T25573 |
themeOf |
production,reduced |
| R2283 |
T3709 |
T3710 |
themeOf |
IFNγ promoters,activities |
| R2284 |
T3711 |
T3719 |
themeOf |
NFκB,binding |
| R2285 |
T3711 |
T3720 |
themeOf |
NFκB,binding |
| R2286 |
T3712 |
T3721 |
themeOf |
NFIL-6,binding |
| R2287 |
T3712 |
T3722 |
themeOf |
NFIL-6,binding |
| R2288 |
T3716 |
T3719 |
themeOf |
NFIL-6consensus,binding |
| R2289 |
T3716 |
T3721 |
themeOf |
NFIL-6consensus,binding |
| R2290 |
T3718 |
T3720 |
themeOf |
Fig. 1A,binding |
| R2291 |
T3718 |
T3722 |
themeOf |
Fig. 1A,binding |
| R2292 |
T3725 |
T3728 |
themeOf |
NFκB p65,binding |
| R2293 |
T3725 |
T3729 |
themeOf |
NFκB p65,binding |
| R2294 |
T3725 |
T3730 |
themeOf |
NFκB p65,binding |
| R2295 |
T3726 |
T3729 |
themeOf |
p50,binding |
| R2296 |
T3726 |
T3731 |
themeOf |
p50,degree |
| R2297 |
T3727 |
T3730 |
themeOf |
Fig. 1A,binding |
| R2298 |
T3727 |
T3732 |
themeOf |
Fig. 1A,degree |
| R2299 |
T3728 |
T3733 |
themeOf |
binding,degree |
| R2300 |
T3729 |
T3734 |
themeOf |
binding,degree |
| R2301 |
T3730 |
T3735 |
themeOf |
binding,degree |
| R2302 |
T3736 |
T3739 |
themeOf |
NFκB p65,binding |
| R2303 |
T3736 |
T3740 |
themeOf |
NFκB p65,binding |
| R2304 |
T3737 |
T3740 |
themeOf |
p50,binding |
| R2305 |
T3738 |
T3741 |
themeOf |
p52,negative |
| R2306 |
T3742 |
T3745 |
themeOf |
NFκB,binding |
| R2307 |
T3742 |
T3746 |
themeOf |
NFκB,binding |
| R2308 |
T3743 |
T3746 |
themeOf |
TNFα promoter,binding |
| R2309 |
T3744 |
T3747 |
themeOf |
NFκB,binding |
| R2310 |
T3747 |
T3748 |
themeOf |
binding,decreased |
| R2311 |
T3749 |
T3752 |
themeOf |
NFAT,binding |
| R2312 |
T3751 |
T3752 |
themeOf |
Fig. 1A,binding |
| R2313 |
T3754 |
T3757 |
themeOf |
NFATc2,binding |
| R2314 |
T3755 |
T3757 |
themeOf |
NFATc1,binding |
| R2315 |
T3755 |
T3758 |
themeOf |
NFATc1,degree |
| R2316 |
T3757 |
T3759 |
themeOf |
binding,degree |
| R259 |
T507 |
T510 |
themeOf |
"nuclear factors κB, AT",binding |
| R260 |
T508 |
T511 |
themeOf |
IL-6,binding |
| R261 |
T510 |
T512 |
themeOf |
binding,modulates |
| R262 |
T511 |
T513 |
themeOf |
binding,modulates |
| R263 |
T514 |
T521 |
themeOf |
nuclear factor (NF)κB,activation |
| R264 |
T515 |
T522 |
themeOf |
NFinterleukin(IL)-6,activation |
| R265 |
T516 |
T523 |
themeOf |
NFAT,activation |
| R266 |
T517 |
T524 |
themeOf |
IL-1β,production |
| R267 |
T518 |
T525 |
themeOf |
IL-6,production |
| R268 |
T519 |
T526 |
themeOf |
tumor necrosis factor α,production |
| R269 |
T520 |
T527 |
themeOf |
interferon γ,production |
| R270 |
T524 |
T528 |
themeOf |
production,induced |
| R271 |
T525 |
T529 |
themeOf |
production,induced |
| R272 |
T526 |
T530 |
themeOf |
production,induced |
| R273 |
T527 |
T531 |
themeOf |
production,induced |
| R274 |
T532 |
T535 |
themeOf |
IL-8,amount |
| R275 |
T532 |
T536 |
themeOf |
IL-8,binding |
| R276 |
T533 |
T536 |
themeOf |
NFκB,binding |
| R277 |
T533 |
T537 |
themeOf |
NFκB,binding |
| R278 |
T534 |
T537 |
themeOf |
IL-8 promoter,binding |
| R279 |
T535 |
T538 |
themeOf |
amount,induced |
| R280 |
T542 |
T544 |
themeOf |
NFAT site,binding |
| R281 |
T543 |
T545 |
themeOf |
IL-1RA promoter,binding |
| R282 |
T543 |
T546 |
themeOf |
IL-1RA promoter,confirmed |
| R283 |
T544 |
T547 |
themeOf |
binding,induced |
| R284 |
T545 |
T548 |
themeOf |
binding,induced |
| R285 |
T549 |
T553 |
themeOf |
NFκB,binding |
| R286 |
T550 |
T554 |
themeOf |
NFIL-6,binding |
| R287 |
T551 |
T555 |
themeOf |
NFAT,binding |
| R288 |
T552 |
T556 |
themeOf |
IL-1RA,increase |
| R289 |
T553 |
T557 |
themeOf |
binding,elevated |
| R290 |
T554 |
T558 |
themeOf |
binding,elevated |
| R291 |
T555 |
T559 |
themeOf |
binding,elevated |
| R292 |
T560 |
T562 |
themeOf |
IL-1β,reduction |
| R293 |
T561 |
T563 |
themeOf |
IL-6,reduction |
| R294 |
T565 |
T566 |
themeOf |
IL-2,production |
| R295 |
T566 |
T567 |
themeOf |
production,decreased |
| R296 |
T568 |
T569 |
themeOf |
IL-1RA gene,regulation |
| R3875 |
T6269 |
T6271 |
themeOf |
IL-1RA,induced |
| R3876 |
T6272 |
T6273 |
themeOf |
TNFα,production |
| R3877 |
T6274 |
T6275 |
themeOf |
TNFα,production |
| R3878 |
T6217 |
T6221 |
themeOf |
TNFα,production |
| R3879 |
T6275 |
T6276 |
themeOf |
production,change |
| R3880 |
T6218 |
T6222 |
themeOf |
IL-8,production |
| R3881 |
T6277 |
T6278 |
themeOf |
TNFα,secretion |
| R3882 |
T6219 |
T6223 |
themeOf |
IL-6,production |
| R3883 |
T6220 |
T6224 |
themeOf |
IFNγ,production |
| R3884 |
T6225 |
T6226 |
themeOf |
IL-1β,production |
| R3885 |
T6279 |
T6280 |
themeOf |
IFNγ,production |
| R3886 |
T6227 |
T6228 |
themeOf |
IL-1β,production |
| R3887 |
T6228 |
T6229 |
themeOf |
production,up-regulation |
| R3888 |
T6230 |
T6232 |
themeOf |
IL-1β,reduction |
| R3889 |
T6281 |
T6284 |
themeOf |
IFNγ,production |
| R3890 |
T6233 |
T6234 |
themeOf |
IL-1β,reduction |
| R3891 |
T6284 |
T6285 |
themeOf |
production,increase |
| R3892 |
T6235 |
T6237 |
themeOf |
IL-6,induced |
| R3893 |
T6236 |
T6238 |
themeOf |
IL-6,production |
| R3894 |
T6238 |
T6239 |
themeOf |
production,LPS-induced |
| R3895 |
T6239 |
T6240 |
themeOf |
LPS-induced,alteration |
| R3896 |
T6285 |
T6286 |
themeOf |
increase,down-regulation |
| R3897 |
T6241 |
T6243 |
themeOf |
IL-6,production |
| R3898 |
T6286 |
T6287 |
themeOf |
down-regulation,increase |
| R3899 |
T6243 |
T6244 |
themeOf |
production,decreased |
| R3900 |
T6292 |
T6296 |
themeOf |
IL-2,production |
| R3901 |
T6247 |
T6249 |
themeOf |
IL-8,produced |
| R3902 |
T6248 |
T6250 |
themeOf |
IL-1RA,produced |
| R3903 |
T6251 |
T6252 |
themeOf |
IL-1RA,production |
| R3904 |
T6252 |
T6253 |
themeOf |
production,alter |
| R3905 |
T6254 |
T6256 |
themeOf |
IL-1RA,production |
| R3906 |
T6293 |
T6297 |
themeOf |
"IL-12, IL-4",production |
| R3907 |
T6256 |
T6257 |
themeOf |
production,increase |
| R3908 |
T6294 |
T6298 |
themeOf |
IL-10,production |
| R3909 |
T6258 |
T6259 |
themeOf |
IL-1RA,elevated |
| R3910 |
T6295 |
T6299 |
themeOf |
TGFβ 1,production |
| R3911 |
T6260 |
T6262 |
themeOf |
IL-8,productions |
| R3912 |
T6261 |
T6263 |
themeOf |
IL-1RA,productions |
| R3913 |
T6262 |
T6264 |
themeOf |
productions,GP-induced |
| R3914 |
T6263 |
T6265 |
themeOf |
productions,GP-induced |
| R3915 |
T6296 |
T6300 |
themeOf |
production,induced |
| R3916 |
T6297 |
T6301 |
themeOf |
production,induced |
| R3917 |
T6268 |
T6270 |
themeOf |
IL-8,induced |
| R3918 |
T6298 |
T6302 |
themeOf |
production,induced |
| R3919 |
T6299 |
T6303 |
themeOf |
production,induced |
| R5662 |
T8700 |
T8704 |
themeOf |
NFIL-6,binding |
| R5663 |
T8701 |
T8703 |
themeOf |
NFAT,binding |
| R5664 |
T8701 |
T8704 |
themeOf |
NFAT,binding |
| R5665 |
T8702 |
T8705 |
themeOf |
IL-1RA,expression |
| R5666 |
T8703 |
T8706 |
themeOf |
binding,Role |
| R5667 |
T8704 |
T8707 |
themeOf |
binding,Role |
| R5668 |
T8705 |
T8708 |
themeOf |
expression,TSST-1-induced |
| R5669 |
T8714 |
T8715 |
themeOf |
IL-1RA promoter,bind |
| R5670 |
T8717 |
T8719 |
themeOf |
TSST-1,binding |
| R5671 |
T8720 |
T8721 |
themeOf |
κB,Binding |
| R5672 |
T8721 |
T8722 |
themeOf |
Binding,elevated |
| R5673 |
T8723 |
T8724 |
themeOf |
NFIL-6 site,binding |
| R5674 |
T8724 |
T8725 |
themeOf |
binding,up-regulation |
| R5675 |
T8726 |
T8727 |
themeOf |
NFIL-6 site,binding |
| R5676 |
T8727 |
T8728 |
themeOf |
binding,increased |
| R5677 |
T8729 |
T8730 |
themeOf |
NFATP2/3,binding |
| R5678 |
T8730 |
T8731 |
themeOf |
binding,increase |
| R6533 |
T9940 |
T9942 |
themeOf |
IL-1β,generating |
| R6534 |
T9941 |
T9943 |
themeOf |
IL-1RA,generating |
| R6535 |
T9947 |
T9949 |
themeOf |
IL-1RA,production |
| R6536 |
T9948 |
T9950 |
themeOf |
IL-1β,production |
| R6537 |
T9951 |
T9955 |
themeOf |
IL-1 dependent release,decrease |
| R7115 |
T10821 |
T10822 |
themeOf |
IL-1RA,reduced |
| R7116 |
T10824 |
T10826 |
themeOf |
IL-1RA,induction |
| R7117 |
T10825 |
T10826 |
causeOf |
GP,induction |
| R7118 |
T10826 |
T10827 |
themeOf |
induction,relevant |
| R7119 |
T10828 |
T10834 |
themeOf |
NFκB,inhibition |
| R7120 |
T10829 |
T10835 |
themeOf |
CAPE [35] and CyA,inhibition |
| R7121 |
T10832 |
T10836 |
themeOf |
IL-1RA mRNA,reduction |
| R7122 |
T10833 |
T10837 |
themeOf |
IL-1RA protein,reduction |
| R7123 |
T10841 |
T10843 |
themeOf |
IL-1RA,decrease |
| R7124 |
T10844 |
T10847 |
themeOf |
IL-1RA protein,levels |
| R7125 |
T10845 |
T10848 |
themeOf |
GP,levels |
| R7126 |
T10849 |
T10851 |
themeOf |
NFκB,inhibition |
| R7127 |
T10849 |
T10852 |
themeOf |
NFκB,binding |
| R7128 |
T10850 |
T10853 |
themeOf |
IL-1RA,release |
| R7129 |
T10852 |
T10854 |
themeOf |
binding,pronounced |
| R7130 |
T10853 |
T10855 |
themeOf |
release,decreased |
| R7635 |
T11941 |
T11944 |
themeOf |
NFκB,binding |
| R7636 |
T11942 |
T11945 |
themeOf |
NFIL-6,binding |
| R7637 |
T11943 |
T11946 |
themeOf |
NFAT,binding |
| R7638 |
T11944 |
T11947 |
themeOf |
binding,induced |
| R7639 |
T11945 |
T11948 |
themeOf |
binding,induced |
| R7640 |
T11946 |
T11949 |
themeOf |
binding,induced |
| R7641 |
T11950 |
T11951 |
themeOf |
NFAT,binding |
| R7870 |
T12234 |
T12238 |
themeOf |
NFκB p65,binding |
| R7871 |
T12235 |
T12238 |
themeOf |
p50,binding |
| R7872 |
T12239 |
T12241 |
themeOf |
IL-8,transcription |
| R7873 |
T12240 |
T12242 |
themeOf |
NFκB p65/65 homodimer,activation |
| R7874 |
T12241 |
T12243 |
themeOf |
transcription,induction |
| R7875 |
T12244 |
T12248 |
themeOf |
NFκB p65,transactivated |
| R7876 |
T12246 |
T12249 |
themeOf |
NFATc2,binding |
| R7877 |
T12246 |
T12250 |
themeOf |
NFATc2,binding |
| R7878 |
T12247 |
T12250 |
themeOf |
IL-8κB site,binding |
| R7879 |
T12256 |
T12258 |
themeOf |
NFκB,binding |
| R7880 |
T12258 |
T12259 |
themeOf |
binding,regulating |
| R7881 |
T12259 |
T12260 |
themeOf |
regulating,supporting |
| R7882 |
T12261 |
T12263 |
themeOf |
IL-1β,induce |
| R7883 |
T12262 |
T12264 |
themeOf |
IL-1RA,induced |
| R7884 |
T12265 |
T12269 |
partOf |
IL-1RA promoter,[34 |
| R7885 |
T12270 |
T12283 |
causeOf |
GP,leads |
| R7886 |
T12271 |
T12278 |
themeOf |
IL-1RA,production |
| R7887 |
T12272 |
T12279 |
themeOf |
NFATP2/3,induction |
| R7888 |
T12272 |
T12281 |
themeOf |
NFATP2/3,binding |
| R7889 |
T12273 |
T12280 |
themeOf |
NFIL-6 DNA,binding |
| R7890 |
T12273 |
T12281 |
themeOf |
NFIL-6 DNA,binding |
| R7891 |
T12275 |
T12282 |
causeOf |
NFAT,due |
| R7892 |
T12278 |
T12283 |
themeOf |
production,leads |
| R7893 |
T12279 |
T12282 |
themeOf |
induction,due |
| R7894 |
T12280 |
T12284 |
themeOf |
binding,induction |
| R7895 |
T12281 |
T12285 |
themeOf |
binding,induction |
| R7896 |
T12286 |
T12293 |
themeOf |
NFκB,decrease |
| R7897 |
T12287 |
T12294 |
themeOf |
NFAT,decrease |
| R7898 |
T12288 |
T12295 |
themeOf |
NFIL-6,decrease |
| R7899 |
T12291 |
T12296 |
themeOf |
IL-1RA,induction |
| R7900 |
T12292 |
T12297 |
themeOf |
Fig,induction |
| R7901 |
T12298 |
T12300 |
themeOf |
IL-8,produce |
| R7902 |
T12299 |
T12301 |
themeOf |
IL-1RA,produce |
| R7903 |
T12304 |
T12412 |
themeOf |
TNFα [43],expression |
| R7904 |
T12414 |
T12420 |
themeOf |
TSST-1,binding |
| R7905 |
T12415 |
T12420 |
themeOf |
MHC-II molecules,binding |
| R7906 |
T12416 |
T12421 |
themeOf |
"T cell receptor, leading to release of mainly IFNγ",kinase |
| R7907 |
T12417 |
T12422 |
themeOf |
TNFα,kinase |
| R7908 |
T12418 |
T12423 |
themeOf |
PI3K,kinase |
| R7909 |
T12419 |
T12424 |
themeOf |
p38,kinase |
| R7910 |
T12425 |
T12426 |
themeOf |
IL-8,induction |
| R7911 |
T12429 |
T12432 |
themeOf |
IL-1β,down-regulation |
| R7912 |
T12430 |
T12433 |
themeOf |
IL-6,down-regulation |
| R7913 |
T12431 |
T12434 |
themeOf |
IL-1RA,up-regulation |
| R7914 |
T12432 |
T12435 |
themeOf |
down-regulation,altered |
| R7915 |
T12433 |
T12436 |
themeOf |
down-regulation,altered |
| R7916 |
T12447 |
T12449 |
themeOf |
NFκB,binding |
| R7917 |
T12447 |
T12450 |
themeOf |
NFκB,binding |
| R7918 |
T12448 |
T12450 |
themeOf |
TNFα promoter,binding |
| R7919 |
T12453 |
T12455 |
themeOf |
NFκB3,binding |
| R7920 |
T12455 |
T12456 |
themeOf |
binding,increased |
| R7921 |
T12457 |
T12470 |
causeOf |
TSST-1,induced |
| R7922 |
T12457 |
T12471 |
causeOf |
TSST-1,induced |
| R7923 |
T12458 |
T12463 |
themeOf |
NFκB,binding |
| R7924 |
T12458 |
T12464 |
themeOf |
NFκB,binding |
| R7925 |
T12459 |
T12464 |
themeOf |
TNFα promoter,binding |
| R7926 |
T12460 |
T12465 |
themeOf |
NFκB3,up-regulation |
| R7927 |
T12461 |
T12466 |
themeOf |
NFκB,up-regulation |
| R7928 |
T12462 |
T12467 |
themeOf |
IL-1RA promoter,up-regulation |
| R7929 |
T12463 |
T12468 |
themeOf |
binding,down-regulation |
| R7930 |
T12463 |
T12470 |
themeOf |
binding,induced |
| R7931 |
T12464 |
T12469 |
themeOf |
binding,down-regulation |
| R7932 |
T12464 |
T12471 |
themeOf |
binding,induced |
| R7933 |
T12484 |
T12486 |
themeOf |
NFIL-6 site [32],binding |
| R7934 |
T12486 |
T12487 |
themeOf |
binding,increase |
| R7935 |
T12488 |
T12489 |
themeOf |
IL-1β/IL-1RA,decrease |
| R7936 |
T12493 |
T12494 |
themeOf |
IL-1β,inactivated |
| R7937 |
T12499 |
T12501 |
themeOf |
sIL-1RA,production |
| R7938 |
T12500 |
T12502 |
themeOf |
IL-1β,production |
| R7939 |
T12501 |
T12503 |
themeOf |
production,controls |
| R7940 |
T12502 |
T12504 |
themeOf |
production,controls |
| R7941 |
T12506 |
T12507 |
themeOf |
NFAT,activation |
| R7942 |
T12508 |
T12511 |
themeOf |
NFκB,Activation |
| R7943 |
T12513 |
T12516 |
causeOf |
LPS,activated |
| R7944 |
T12514 |
T12517 |
causeOf |
peptidoglycan,activated |
| R7945 |
T12515 |
T12516 |
themeOf |
IL-1RA,activated |
| R7946 |
T12515 |
T12517 |
themeOf |
IL-1RA,activated |
