| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T198 |
0-4 |
Protein |
denotes |
Sox6 |
| T201 |
14-22 |
Negative_regulation |
denotes |
Silences |
| T199 |
23-37 |
Protein |
denotes |
Epsilon Globin |
| T200 |
38-48 |
Gene_expression |
denotes |
Expression |
| T202 |
127-131 |
Protein |
denotes |
Sox6 |
| T203 |
151-182 |
Protein |
denotes |
Sox transcription factor family |
| T207 |
191-198 |
Negative_regulation |
denotes |
defined |
| T206 |
191-198 |
Negative_regulation |
denotes |
defined |
| T205 |
254-260 |
Entity |
denotes |
domain |
| T204 |
310-313 |
Protein |
denotes |
Sry |
| T208 |
352-356 |
Protein |
denotes |
Sox6 |
| T209 |
450-454 |
Protein |
denotes |
Sox6 |
| T212 |
455-464 |
Negative_regulation |
denotes |
deficient |
| T210 |
472-477 |
Protein |
denotes |
p100H |
| T211 |
479-488 |
Protein |
denotes |
ɛy globin |
| T214 |
505-514 |
Gene_expression |
denotes |
expressed |
| T213 |
505-514 |
Gene_expression |
denotes |
expressed |
| T215 |
730-734 |
Protein |
denotes |
Sox6 |
| T216 |
865-869 |
Protein |
denotes |
Sox6 |
| T218 |
902-909 |
Binding |
denotes |
binding |
| T217 |
920-928 |
Entity |
denotes |
promoter |
| T222 |
941-951 |
Gene_expression |
denotes |
expression |
| T219 |
955-959 |
Protein |
denotes |
Sox6 |
| T220 |
1021-1026 |
Protein |
denotes |
p100H |
| T221 |
1067-1071 |
Protein |
denotes |
Sox6 |
| T223 |
1141-1145 |
Protein |
denotes |
Sox6 |
| T227 |
1149-1157 |
Positive_regulation |
denotes |
required |
| T226 |
1162-1171 |
Negative_regulation |
denotes |
silencing |
| T224 |
1178-1184 |
Protein |
denotes |
globin |
| T225 |
1238-1242 |
Protein |
denotes |
Sox6 |
| T228 |
1279-1283 |
Protein |
denotes |
Sox6 |
| T230 |
1284-1294 |
Regulation |
denotes |
regulation |
| T229 |
1298-1307 |
Protein |
denotes |
ɛy globin |
| T1500 |
2855-2871 |
Protein |
denotes |
Sry type HMG box |
| T1501 |
2873-2877 |
Protein |
denotes |
Sox6 |
| T1505 |
2884-2890 |
Binding |
denotes |
member |
| T1504 |
2884-2890 |
Binding |
denotes |
member |
| T1503 |
2884-2890 |
Binding |
denotes |
member |
| T1502 |
2898-2929 |
Protein |
denotes |
Sox transcription factor family |
| T1506 |
3069-3072 |
Protein |
denotes |
Sox |
| T1507 |
3095-3099 |
Binding |
denotes |
bind |
| T1508 |
3299-3311 |
Protein |
denotes |
Sox proteins |
| T1509 |
3535-3539 |
Protein |
denotes |
Sox6 |
| T1510 |
3697-3701 |
Protein |
denotes |
Sox6 |
| T1516 |
3802-3811 |
Localization |
denotes |
Depletion |
| T1511 |
3815-3819 |
Protein |
denotes |
Sox6 |
| T1520 |
3887-3897 |
Gene_expression |
denotes |
expression |
| T1519 |
3887-3897 |
Gene_expression |
denotes |
expression |
| T1518 |
3887-3897 |
Gene_expression |
denotes |
expression |
| T1517 |
3887-3897 |
Gene_expression |
denotes |
expression |
| T1512 |
3905-3915 |
Protein |
denotes |
HMG domain |
| T1513 |
3926-3930 |
Protein |
denotes |
Sox6 |
| T1514 |
3932-3936 |
Protein |
denotes |
Sox9 |
| T1515 |
3941-3944 |
Protein |
denotes |
Sry |
| T1521 |
4051-4055 |
Protein |
denotes |
Sox6 |
| T1522 |
4137-4141 |
Protein |
denotes |
Sox6 |
| T1523 |
4296-4300 |
Protein |
denotes |
Sox6 |
| T1524 |
4402-4407 |
Protein |
denotes |
p100H |
| T1525 |
4524-4529 |
Protein |
denotes |
p100H |
| T1527 |
4593-4601 |
Positive_regulation |
denotes |
disrupts |
| T1526 |
4626-4635 |
Protein |
denotes |
Sox6 gene |
| T1528 |
4731-4737 |
Protein |
denotes |
p gene |
| T1529 |
4781-4806 |
Protein |
denotes |
Sox6 transcription factor |
| T1530 |
4856-4872 |
Protein |
denotes |
HMG box proteins |
| T1531 |
4894-4897 |
Protein |
denotes |
Sry |
| T1532 |
4934-4965 |
Protein |
denotes |
Sox transcription factor family |
| T1535 |
4982-4986 |
Binding |
denotes |
bind |
| T1537 |
5076-5085 |
Gene_expression |
denotes |
expressed |
| T1536 |
5076-5085 |
Gene_expression |
denotes |
expressed |
| T1533 |
5086-5090 |
Protein |
denotes |
HMG1 |
| T1534 |
5095-5108 |
Protein |
denotes |
HMG2 proteins |
| T1538 |
5162-5174 |
Protein |
denotes |
HMG proteins |
| T1539 |
5340-5352 |
Protein |
denotes |
HMG proteins |
| T1541 |
5372-5380 |
Regulation |
denotes |
modulate |
| T1540 |
5381-5389 |
Protein |
denotes |
β-globin |
| T1542 |
5409-5423 |
Protein |
denotes |
mouse β-globin |
| T1543 |
5809-5823 |
Protein |
denotes |
β-globin genes |
| T1544 |
5828-5837 |
Gene_expression |
denotes |
expressed |
| T1545 |
5927-5945 |
Protein |
denotes |
embryonic yolk sac |
| T1547 |
6115-6122 |
Gene_expression |
denotes |
express |
| T1546 |
6123-6138 |
Protein |
denotes |
adult β globins |
| T1549 |
6237-6246 |
Negative_regulation |
denotes |
silencing |
| T1548 |
6273-6281 |
Protein |
denotes |
ɛ globin |
| T1550 |
6485-6493 |
Protein |
denotes |
γ-globin |
| T1551 |
6497-6511 |
Protein |
denotes |
adult β-globin |
| T1552 |
6512-6518 |
Entity |
denotes |
switch |
| T1554 |
6522-6532 |
Regulation |
denotes |
controlled |
| T1553 |
6522-6532 |
Regulation |
denotes |
controlled |
| T1556 |
6611-6620 |
Negative_regulation |
denotes |
silencing |
| T1555 |
6625-6638 |
Protein |
denotes |
ɛ globin gene |
| T1557 |
7036-7042 |
Protein |
denotes |
GATA-1 |
| T1558 |
7044-7048 |
Protein |
denotes |
YY-1 |
| T1559 |
7050-7057 |
Protein |
denotes |
COUP-TF |
| T1560 |
7111-7115 |
Binding |
denotes |
bind |
| T1561 |
7488-7492 |
Protein |
denotes |
Sox6 |
| T1562 |
7496-7507 |
Positive_regulation |
denotes |
upregulated |
| T1563 |
7666-7670 |
Protein |
denotes |
Sox6 |
| T1565 |
7855-7865 |
Gene_expression |
denotes |
expression |
| T1564 |
7879-7891 |
Protein |
denotes |
globin genes |
| T1567 |
7944-7954 |
Gene_expression |
denotes |
expression |
| T1566 |
7975-7986 |
Protein |
denotes |
globin gene |
| T1570 |
8026-8033 |
Regulation |
denotes |
effects |
| T1568 |
8037-8041 |
Protein |
denotes |
Sox6 |
| T1569 |
8049-8063 |
Protein |
denotes |
ɛy globin gene |
| T1571 |
8078-8082 |
Protein |
denotes |
Sox6 |
| T1576 |
8083-8088 |
Binding |
denotes |
binds |
| T1575 |
8083-8088 |
Binding |
denotes |
binds |
| T1573 |
8105-8113 |
Entity |
denotes |
promoter |
| T1572 |
8117-8126 |
Protein |
denotes |
ɛy globin |
| T1577 |
8131-8140 |
Negative_regulation |
denotes |
represses |
| T1574 |
8145-8158 |
Transcription |
denotes |
transcription |
| T1578 |
8184-8188 |
Protein |
denotes |
Sox6 |
| T1580 |
8196-8205 |
Gene_expression |
denotes |
expressed |
| T1582 |
8240-8249 |
Gene_expression |
denotes |
expressed |
| T1581 |
8240-8249 |
Gene_expression |
denotes |
expressed |
| T1583 |
8279-8289 |
Gene_expression |
denotes |
expression |
| T1579 |
8301-8310 |
Protein |
denotes |
ɛy globin |
| T1587 |
8319-8326 |
Negative_regulation |
denotes |
absence |
| T1584 |
8330-8334 |
Protein |
denotes |
Sox6 |
| T1585 |
8336-8345 |
Protein |
denotes |
ɛy globin |
| T1586 |
8410-8414 |
Protein |
denotes |
Sox6 |
| T4496 |
8476-8486 |
Gene_expression |
denotes |
Expression |
| T4494 |
8494-8510 |
Protein |
denotes |
Embryonic Globin |
| T4495 |
8519-8523 |
Protein |
denotes |
Sox6 |
| T4497 |
8524-8533 |
Negative_regulation |
denotes |
Deficient |
| T4498 |
8546-8557 |
Protein |
denotes |
globin gene |
| T4500 |
8589-8600 |
Positive_regulation |
denotes |
upregulated |
| T4499 |
8676-8699 |
Protein |
denotes |
Sox6 downstream targets |
| T4501 |
8778-8782 |
Protein |
denotes |
Sox6 |
| T4505 |
8897-8907 |
Gene_expression |
denotes |
expression |
| T4504 |
8897-8907 |
Gene_expression |
denotes |
expression |
| T4502 |
8924-8936 |
Protein |
denotes |
globin genes |
| T4503 |
8940-8945 |
Protein |
denotes |
p100H |
| T4506 |
9457-9466 |
Protein |
denotes |
ɛy globin |
| T4508 |
9505-9515 |
Gene_expression |
denotes |
expression |
| T4507 |
9525-9539 |
Protein |
denotes |
adult β globin |
| T4509 |
9743-9749 |
Protein |
denotes |
globin |
| T4510 |
9750-9760 |
Gene_expression |
denotes |
expression |
| T4512 |
10313-10323 |
Gene_expression |
denotes |
expression |
| T4511 |
10374-10381 |
Protein |
denotes |
WT mice |
| T5701 |
10849-10853 |
Protein |
denotes |
Sox6 |
| T5702 |
10885-10893 |
Entity |
denotes |
Promoter |
| T5703 |
10986-10993 |
Protein |
denotes |
ɛy mRNA |
| T5704 |
11067-11071 |
Protein |
denotes |
Sox6 |
| T5706 |
11101-11109 |
Entity |
denotes |
promoter |
| T5707 |
11246-11255 |
Gene_expression |
denotes |
expresses |
| T5705 |
11274-11286 |
Protein |
denotes |
beta globins |
| T5708 |
11343-11346 |
Protein |
denotes |
Luc |
| T5709 |
11453-11477 |
Protein |
denotes |
luciferase reporter gene |
| T5713 |
11538-11552 |
Positive_regulation |
denotes |
Overexpression |
| T5712 |
11538-11552 |
Gene_expression |
denotes |
Overexpression |
| T5710 |
11556-11560 |
Protein |
denotes |
Sox6 |
| T5714 |
11630-11640 |
Negative_regulation |
denotes |
repression |
| T5711 |
11644-11658 |
Protein |
denotes |
E-Luc reporter |
| T5720 |
11694-11708 |
Positive_regulation |
denotes |
overexpression |
| T5719 |
11694-11708 |
Gene_expression |
denotes |
overexpression |
| T5715 |
11724-11728 |
Protein |
denotes |
Sox6 |
| T5716 |
11752-11755 |
Protein |
denotes |
HMG |
| T5721 |
11756-11762 |
Entity |
denotes |
domain |
| T5717 |
11784-11803 |
Protein |
denotes |
p 100H mouse allele |
| T5718 |
11824-11827 |
Protein |
denotes |
Luc |
| T5722 |
11875-11879 |
Protein |
denotes |
Sox6 |
| T5723 |
13323-13327 |
Protein |
denotes |
Sox6 |
| T5727 |
13372-13380 |
Binding |
denotes |
interact |
| T5726 |
13372-13380 |
Binding |
denotes |
interact |
| T5728 |
13395-13404 |
Gene_expression |
denotes |
expressed |
| T5724 |
13419-13424 |
Protein |
denotes |
CtBP2 |
| T5725 |
13433-13451 |
Protein |
denotes |
fgf-3 promoter [5] |
| T5729 |
13453-13458 |
Protein |
denotes |
CtBP2 |
| T5730 |
13462-13471 |
Gene_expression |
denotes |
expressed |
| T5736 |
13534-13545 |
Binding |
denotes |
interaction |
| T5731 |
13551-13556 |
Protein |
denotes |
CtBP2 |
| T5739 |
13560-13568 |
Positive_regulation |
denotes |
required |
| T5732 |
13573-13577 |
Protein |
denotes |
Sox6 |
| T5737 |
13578-13588 |
Gene_expression |
denotes |
repression |
| T5733 |
13655-13667 |
Protein |
denotes |
Sox6 protein |
| T5740 |
13722-13729 |
Negative_regulation |
denotes |
abolish |
| T5734 |
13730-13734 |
Protein |
denotes |
Sox6 |
| T5735 |
13735-13740 |
Protein |
denotes |
CtBP2 |
| T5738 |
13741-13752 |
Binding |
denotes |
interaction |
| T5741 |
13795-13798 |
Protein |
denotes |
HMG |
| T5742 |
13851-13855 |
Protein |
denotes |
Sox6 |
| T5743 |
13958-13962 |
Protein |
denotes |
Sox6 |
| T5745 |
13980-13988 |
Entity |
denotes |
promoter |
| T5744 |
13994-13999 |
Protein |
denotes |
CtBP2 |
| T5746 |
14164-14168 |
Protein |
denotes |
Sox6 |
| T5747 |
14169-14179 |
Gene_expression |
denotes |
repression |
| T5748 |
14223-14226 |
Protein |
denotes |
Sox |
| T5749 |
14227-14231 |
Protein |
denotes |
Sox6 |
| T7341 |
16872-16876 |
Protein |
denotes |
Sox6 |
| T7343 |
16886-16891 |
Binding |
denotes |
Binds |
| T7342 |
16902-16910 |
Entity |
denotes |
Promoter |
| T7344 |
16911-16915 |
Protein |
denotes |
Sox6 |
| T7345 |
17085-17089 |
Protein |
denotes |
Sox6 |
| T7347 |
17102-17112 |
Binding |
denotes |
associated |
| T7346 |
17220-17224 |
Protein |
denotes |
Sox6 |
| T7348 |
17502-17505 |
Protein |
denotes |
Sox |
| T7349 |
17506-17510 |
Protein |
denotes |
Sox6 |
| T7350 |
17636-17639 |
Protein |
denotes |
Sox |
| T7351 |
17640-17644 |
Protein |
denotes |
Sox6 |
| T7352 |
17672-17676 |
Protein |
denotes |
Sox6 |
| T7353 |
17699-17708 |
Binding |
denotes |
associate |
| T7354 |
17866-17870 |
Protein |
denotes |
Sox6 |
| T7355 |
17895-17900 |
Protein |
denotes |
c-Myc |
| T7356 |
17905-17909 |
Protein |
denotes |
Sox6 |
| T7357 |
17973-17977 |
Protein |
denotes |
Sox6 |
| T7358 |
18027-18030 |
Protein |
denotes |
Myc |
| T7360 |
18042-18047 |
Binding |
denotes |
binds |
| T7359 |
18075-18079 |
Protein |
denotes |
Sox6 |
| T7362 |
18282-18289 |
Gene_expression |
denotes |
express |
| T7361 |
18290-18305 |
Protein |
denotes |
adult β globins |
| T7363 |
18324-18328 |
Protein |
denotes |
Sox6 |
| T7364 |
18338-18343 |
Binding |
denotes |
binds |
| T7365 |
18412-18415 |
Protein |
denotes |
Sox |
| T7366 |
18416-18420 |
Protein |
denotes |
Sox6 |
| T7370 |
18456-18464 |
Positive_regulation |
denotes |
required |
| T7369 |
18456-18464 |
Positive_regulation |
denotes |
required |
| T7368 |
18473-18480 |
Binding |
denotes |
binding |
| T7367 |
18473-18480 |
Binding |
denotes |
binding |
| T7371 |
18550-18553 |
Protein |
denotes |
Sox |
| T7372 |
18554-18558 |
Protein |
denotes |
Sox6 |
| T7376 |
18585-18592 |
Negative_regulation |
denotes |
abolish |
| T7375 |
18585-18592 |
Negative_regulation |
denotes |
abolish |
| T7374 |
18610-18617 |
Binding |
denotes |
compete |
| T7373 |
18610-18617 |
Binding |
denotes |
compete |
| T7377 |
18686-18688 |
Protein |
denotes |
WT |
| T7378 |
18689-18696 |
Binding |
denotes |
binding |
| T7379 |
18755-18758 |
Protein |
denotes |
Sox |
| T7380 |
18759-18763 |
Protein |
denotes |
Sox6 |
| T7381 |
18832-18835 |
Protein |
denotes |
Sox |
| T7382 |
18836-18840 |
Protein |
denotes |
Sox6 |
| T7383 |
18884-18888 |
Protein |
denotes |
Sox6 |
| T7384 |
18967-19005 |
Protein |
denotes |
mutant ɛy promoter reporter constructs |
| T7385 |
19031-19034 |
Protein |
denotes |
Sox |
| T7386 |
19035-19039 |
Protein |
denotes |
Sox6 |
| T7387 |
19215-19219 |
Protein |
denotes |
Sox6 |
| T7388 |
19272-19276 |
Protein |
denotes |
Sox6 |
| T7390 |
19277-19282 |
Binding |
denotes |
binds |
| T7389 |
19293-19301 |
Entity |
denotes |
promoter |
| T7391 |
19369-19373 |
Protein |
denotes |
Sox6 |
| T7392 |
19477-19490 |
Protein |
denotes |
Sox6 antibody |
| T7393 |
19572-19576 |
Protein |
denotes |
Sox6 |
| T7394 |
19628-19631 |
Protein |
denotes |
IgG |
| T7395 |
19731-19735 |
Protein |
denotes |
Sox6 |
| T7396 |
19783-19790 |
Binding |
denotes |
binding |
| T9096 |
20675-20685 |
Gene_expression |
denotes |
Expression |
| T9094 |
20692-20698 |
Protein |
denotes |
Globin |
| T9095 |
20702-20706 |
Protein |
denotes |
Sox6 |
| T9097 |
20707-20716 |
Negative_regulation |
denotes |
Deficient |
| T9098 |
20820-20834 |
Protein |
denotes |
ɛy globin gene |
| T9099 |
20850-20859 |
Gene_expression |
denotes |
expressed |
| T9100 |
20890-20898 |
Positive_regulation |
denotes |
silenced |
| T9104 |
20963-20973 |
Gene_expression |
denotes |
expression |
| T9101 |
20977-20986 |
Protein |
denotes |
ɛy globin |
| T9105 |
20990-20993 |
Positive_regulation |
denotes |
due |
| T9106 |
21050-21060 |
Gene_expression |
denotes |
expression |
| T9102 |
21067-21073 |
Protein |
denotes |
globin |
| T9103 |
21140-21158 |
Protein |
denotes |
globin transcripts |
| T9107 |
21226-21235 |
Protein |
denotes |
ɛy globin |
| T9108 |
21243-21252 |
Gene_expression |
denotes |
expressed |
| T9109 |
21361-21368 |
Protein |
denotes |
ɛy mRNA |
| T9110 |
21369-21379 |
Gene_expression |
denotes |
expression |
| T9113 |
21450-21460 |
Gene_expression |
denotes |
expression |
| T9111 |
21473-21479 |
Protein |
denotes |
globin |
| T9112 |
21508-21510 |
Protein |
denotes |
WT |
| T9114 |
21788-21792 |
Protein |
denotes |
Sox6 |
| T9836 |
22437-22447 |
Gene_expression |
denotes |
Expression |
| T9835 |
22459-22463 |
Protein |
denotes |
Sox6 |
| T9837 |
22530-22534 |
Protein |
denotes |
Sox6 |
| T9840 |
22535-22544 |
Negative_regulation |
denotes |
deficient |
| T9841 |
22562-22569 |
Gene_expression |
denotes |
express |
| T9838 |
22573-22579 |
Protein |
denotes |
globin |
| T9839 |
22645-22649 |
Protein |
denotes |
Sox6 |
| T9843 |
22744-22754 |
Gene_expression |
denotes |
expression |
| T9842 |
22766-22770 |
Protein |
denotes |
Sox6 |
| T9844 |
22857-22861 |
Protein |
denotes |
Sox6 |
| T9845 |
23040-23044 |
Protein |
denotes |
Sox6 |
| T9846 |
23055-23066 |
Transcription |
denotes |
transcribed |
| T9847 |
23155-23159 |
Protein |
denotes |
Sox6 |
| T9848 |
23160-23170 |
Gene_expression |
denotes |
expression |
| T9849 |
23315-23324 |
Protein |
denotes |
ɛy globin |
| T9851 |
23335-23344 |
Gene_expression |
denotes |
expressed |
| T9850 |
23423-23427 |
Protein |
denotes |
Sox6 |
| T10509 |
24593-24597 |
Protein |
denotes |
Sox6 |
| T10510 |
24702-24707 |
Protein |
denotes |
p100H |
| T10513 |
25166-25175 |
Negative_regulation |
denotes |
silencing |
| T10511 |
25180-25194 |
Protein |
denotes |
ɛy globin gene |
| T10512 |
25196-25200 |
Protein |
denotes |
Sox6 |
| T11600 |
25580-25584 |
Protein |
denotes |
Sox6 |
| T11602 |
25622-25632 |
Regulation |
denotes |
regulation |
| T11601 |
25646-25658 |
Protein |
denotes |
globin genes |
| T11603 |
25667-25671 |
Protein |
denotes |
Sox6 |
| T11607 |
25705-25711 |
Regulation |
denotes |
effect |
| T11604 |
25729-25741 |
Protein |
denotes |
globin genes |
| T11606 |
25771-25783 |
Positive_regulation |
denotes |
upregulation |
| T11605 |
25791-25805 |
Protein |
denotes |
ɛy globin gene |
| T11608 |
25807-25811 |
Protein |
denotes |
Sox6 |
| T11612 |
25835-25840 |
Binding |
denotes |
binds |
| T11610 |
25857-25865 |
Entity |
denotes |
promoter |
| T11611 |
25881-25890 |
Negative_regulation |
denotes |
represses |
| T11609 |
25895-25909 |
Protein |
denotes |
ɛy-globin gene |
| T11613 |
25940-25944 |
Protein |
denotes |
Sox6 |
| T11614 |
25971-25981 |
Protein |
denotes |
Sox family |
| T11615 |
26008-26012 |
Protein |
denotes |
Sox5 |
| T11616 |
26035-26055 |
Protein |
denotes |
Group D Sox proteins |
| T11617 |
26168-26172 |
Protein |
denotes |
Sox5 |
| T11618 |
26177-26181 |
Protein |
denotes |
Sox6 |
| T11619 |
26251-26263 |
Protein |
denotes |
Sox proteins |
| T11620 |
26322-26326 |
Protein |
denotes |
Sox6 |
| T11621 |
26327-26332 |
Binding |
denotes |
binds |
| T11622 |
26453-26473 |
Protein |
denotes |
group D Sox proteins |
| T11623 |
26483-26487 |
Protein |
denotes |
Sox6 |
| T11627 |
26498-26504 |
Binding |
denotes |
harbor |
| T11626 |
26498-26504 |
Binding |
denotes |
harbor |
| T11624 |
26514-26517 |
Protein |
denotes |
HMG |
| T11628 |
26569-26576 |
Binding |
denotes |
binding |
| T11625 |
26580-26593 |
Protein |
denotes |
D-Sox protein |
| T11629 |
26644-26648 |
Protein |
denotes |
Sox6 |
| T11630 |
26697-26700 |
Protein |
denotes |
Sox |
| T11631 |
26701-26705 |
Protein |
denotes |
Sox6 |
| T13422 |
26764-26773 |
Positive_regulation |
denotes |
essential |
| T13247 |
26778-26782 |
Protein |
denotes |
Sox6 |
| T13285 |
26783-26790 |
Binding |
denotes |
binding |
| T13248 |
26801-26809 |
Entity |
denotes |
promoter |
| T13421 |
26814-26824 |
Negative_regulation |
denotes |
repression |
| T13423 |
26893-26897 |
Protein |
denotes |
Sox6 |
| T13425 |
26898-26903 |
Binding |
denotes |
binds |
| T13427 |
26952-26961 |
Binding |
denotes |
homodimer |
| T13426 |
26952-26961 |
Binding |
denotes |
homodimer |
| T13428 |
26970-26981 |
Binding |
denotes |
heterodimer |
| T13424 |
26993-27005 |
Protein |
denotes |
Sox proteins |
| T13429 |
27015-27018 |
Protein |
denotes |
Sox |
| T13430 |
27171-27183 |
Binding |
denotes |
interactions |
| T13431 |
27319-27323 |
Protein |
denotes |
Sox6 |
| T13432 |
27357-27361 |
Protein |
denotes |
Sox6 |
| T13433 |
27421-27438 |
Protein |
denotes |
globin repressors |
| T13436 |
27461-27465 |
Binding |
denotes |
bind |
| T13434 |
27492-27495 |
Protein |
denotes |
Sox |
| T13435 |
27496-27500 |
Protein |
denotes |
Sox6 |
| T13437 |
27568-27572 |
Protein |
denotes |
Sox6 |
| T13438 |
27579-27587 |
Binding |
denotes |
interact |
| T13439 |
27686-27690 |
Protein |
denotes |
Sox6 |
| T13440 |
27790-27793 |
Protein |
denotes |
Sox |
| T13441 |
27803-27807 |
Binding |
denotes |
bind |
| T13442 |
27887-27891 |
Binding |
denotes |
bind |
| T13443 |
27968-27981 |
Protein |
denotes |
Sox6 proteins |
| T13444 |
28221-28225 |
Protein |
denotes |
Sox6 |
| T13445 |
28254-28261 |
Binding |
denotes |
binding |
| T13446 |
28312-28319 |
Binding |
denotes |
binding |
| T13447 |
28455-28459 |
Protein |
denotes |
EKLF |
| T13448 |
28478-28485 |
Binding |
denotes |
binding |
| T13449 |
28515-28518 |
Protein |
denotes |
HMG |
| T13450 |
28568-28578 |
Protein |
denotes |
Sox family |
| T13451 |
28606-28611 |
Protein |
denotes |
HMG-I |
| T13452 |
28616-28621 |
Protein |
denotes |
HMG-Y |
| T13455 |
28644-28648 |
Binding |
denotes |
bind |
| T13454 |
28644-28648 |
Binding |
denotes |
bind |
| T13453 |
28668-28686 |
Protein |
denotes |
β globin silencers |
| T13456 |
28789-28793 |
Protein |
denotes |
Sox6 |
| T13459 |
28794-28804 |
Gene_expression |
denotes |
expression |
| T13457 |
28911-28915 |
Protein |
denotes |
Sox6 |
| T13461 |
28916-28925 |
Negative_regulation |
denotes |
represses |
| T13458 |
28926-28935 |
Protein |
denotes |
ɛy globin |
| T13460 |
28936-28946 |
Gene_expression |
denotes |
expression |
| T13463 |
29062-29072 |
Gene_expression |
denotes |
expression |
| T13462 |
29076-29085 |
Protein |
denotes |
ɛy globin |
| T13464 |
29110-29113 |
Positive_regulation |
denotes |
due |
| T13465 |
29267-29271 |
Protein |
denotes |
Sox6 |
| T13468 |
29314-29321 |
Negative_regulation |
denotes |
silence |
| T13466 |
29325-29331 |
Protein |
denotes |
globin |
| T13467 |
29332-29342 |
Gene_expression |
denotes |
expression |
| T13471 |
29348-29358 |
Gene_expression |
denotes |
expression |
| T13469 |
29368-29377 |
Protein |
denotes |
ɛy globin |
| T13470 |
29392-29396 |
Protein |
denotes |
Sox6 |
| T13473 |
29597-29607 |
Gene_expression |
denotes |
expression |
| T13472 |
29618-29629 |
Protein |
denotes |
globin gene |
| T13479 |
29677-29687 |
Gene_expression |
denotes |
expression |
| T13478 |
29677-29687 |
Gene_expression |
denotes |
expression |
| T13481 |
29688-29694 |
Positive_regulation |
denotes |
levels |
| T13480 |
29688-29694 |
Positive_regulation |
denotes |
levels |
| T13474 |
29718-29730 |
Protein |
denotes |
globin genes |
| T13475 |
29732-29741 |
Protein |
denotes |
ζ and βh1 |
| T13476 |
29762-29779 |
Protein |
denotes |
p100H homozygotes |
| T13477 |
29795-29797 |
Protein |
denotes |
WT |
| T13482 |
29818-29827 |
Protein |
denotes |
ζ and βh1 |
| T13483 |
29896-29905 |
Protein |
denotes |
ɛy globin |
| T13484 |
29928-29938 |
Gene_expression |
denotes |
expression |
| T13485 |
30047-30051 |
Protein |
denotes |
Sox6 |
| T13486 |
30086-30098 |
Protein |
denotes |
globin genes |
| T13487 |
30425-30436 |
Protein |
denotes |
globin gene |
| T13489 |
30437-30447 |
Gene_expression |
denotes |
expression |
| T13490 |
30466-30472 |
Positive_regulation |
denotes |
levels |
| T13488 |
30476-30485 |
Protein |
denotes |
ɛy globin |
| T13491 |
30604-30617 |
Protein |
denotes |
ζ and βh1 RNA |
| T13493 |
30623-30635 |
Positive_regulation |
denotes |
undetectable |
| T13492 |
30681-30691 |
Protein |
denotes |
globin RNA |
| T13494 |
30715-30723 |
Positive_regulation |
denotes |
elevated |
| T13495 |
30858-30862 |
Protein |
denotes |
Sox6 |
| T13500 |
30900-30907 |
Negative_regulation |
denotes |
silence |
| T13496 |
30911-30917 |
Protein |
denotes |
globin |
| T13498 |
30918-30928 |
Gene_expression |
denotes |
expression |
| T13499 |
30962-30972 |
Regulation |
denotes |
regulation |
| T13497 |
30976-30985 |
Protein |
denotes |
ɛy-globin |
| T13501 |
31010-31014 |
Protein |
denotes |
Sox6 |
| T13503 |
31015-31024 |
Regulation |
denotes |
regulates |
| T13502 |
31045-31057 |
Protein |
denotes |
globin genes |
| T13504 |
31084-31088 |
Protein |
denotes |
Sox6 |
| T13505 |
31173-31178 |
Protein |
denotes |
p100H |
| T13506 |
31632-31636 |
Protein |
denotes |
Sox6 |
| T13507 |
31899-31903 |
Protein |
denotes |
Sox6 |
| T13510 |
31904-31913 |
Negative_regulation |
denotes |
deficient |
| T13508 |
31991-32003 |
Protein |
denotes |
Sox proteins |
| T13511 |
32005-32014 |
Gene_expression |
denotes |
expressed |
| T13509 |
32101-32104 |
Protein |
denotes |
Sox |
| T13512 |
32346-32350 |
Protein |
denotes |
Sox6 |
| T13513 |
32435-32439 |
Protein |
denotes |
Sox6 |
| T13516 |
32559-32571 |
Positive_regulation |
denotes |
reactivation |
| T13514 |
32575-32589 |
Protein |
denotes |
human ɛ-globin |
| T13515 |
32745-32753 |
Protein |
denotes |
ɛ-globin |
| T13517 |
32759-32768 |
Negative_regulation |
denotes |
silencing |
| T13518 |
32818-32822 |
Protein |
denotes |
Sox6 |
| T13520 |
32830-32835 |
Binding |
denotes |
binds |
| T13519 |
32855-32863 |
Entity |
denotes |
promoter |
| T13521 |
32932-32936 |
Protein |
denotes |
Sox6 |
| T13522 |
33037-33041 |
Protein |
denotes |
Sox6 |
| T13525 |
33054-33063 |
Positive_regulation |
denotes |
important |
| T13523 |
33067-33081 |
Protein |
denotes |
human ɛ globin |
| T13524 |
33082-33091 |
Negative_regulation |
denotes |
silencing |
| T13526 |
33235-33239 |
Protein |
denotes |
Sox6 |
| T13527 |
33298-33317 |
Protein |
denotes |
human ɛ globin gene |
| T13528 |
33370-33374 |
Protein |
denotes |
Sox6 |
| T13529 |
33442-33446 |
Protein |
denotes |
Sox6 |
| T13530 |
33499-33507 |
Protein |
denotes |
ɛ globin |
| T13531 |
33508-33518 |
Regulation |
denotes |
regulation |
| T16489 |
33769-33789 |
Protein |
denotes |
ɛy proximal promoter |
| T16490 |
33825-33834 |
Protein |
denotes |
ɛy globin |
| T16491 |
33971-33976 |
Protein |
denotes |
EcoRI |
| T16492 |
34036-34049 |
Protein |
denotes |
ɛ globin gene |
| T16498 |
34264-34273 |
Gene_expression |
denotes |
contained |
| T16497 |
34264-34273 |
Gene_expression |
denotes |
contained |
| T16493 |
34274-34278 |
Protein |
denotes |
XhoI |
| T16494 |
34283-34296 |
Protein |
denotes |
HindIII sites |
| T16495 |
34362-34385 |
Protein |
denotes |
firefly luciferase gene |
| T16496 |
34389-34393 |
Protein |
denotes |
pGL3 |
| T16499 |
34455-34459 |
Protein |
denotes |
SstI |
| T16500 |
34460-34464 |
Protein |
denotes |
XhoI |
| T16501 |
34477-34486 |
Protein |
denotes |
μLCRβ 9.3 |
| T16502 |
34627-34637 |
Protein |
denotes |
luciferase |
| T16503 |
34638-34648 |
Gene_expression |
denotes |
expression |
| T16504 |
34780-34789 |
Protein |
denotes |
XhoI site |
| T16505 |
35093-35100 |
Protein |
denotes |
MHB1507 |
| T16506 |
35219-35231 |
Protein |
denotes |
HindIII site |
| T16507 |
35233-35240 |
Protein |
denotes |
MHB1477 |
| T16508 |
35286-35290 |
Protein |
denotes |
Sox6 |
| T16513 |
35317-35328 |
Positive_regulation |
denotes |
overexpress |
| T16512 |
35317-35328 |
Positive_regulation |
denotes |
overexpress |
| T16511 |
35317-35328 |
Gene_expression |
denotes |
overexpress |
| T16510 |
35317-35328 |
Gene_expression |
denotes |
overexpress |
| T16509 |
35329-35333 |
Protein |
denotes |
Sox6 |
| T16514 |
35362-35366 |
Protein |
denotes |
Sox6 |
| T16515 |
35393-35397 |
Protein |
denotes |
Sox6 |
| T16517 |
35418-35423 |
Negative_regulation |
denotes |
lacks |
| T16516 |
35428-35438 |
Protein |
denotes |
HMG domain |
| T16518 |
35498-35501 |
Protein |
denotes |
Sox |
| T16519 |
35502-35506 |
Protein |
denotes |
Sox6 |
| T16520 |
35607-35650 |
Protein |
denotes |
mutagenized ɛy promoter reporter constructs |
| T17411 |
35904-35915 |
Protein |
denotes |
globin mRNA |
| T17412 |
35998-36010 |
Protein |
denotes |
globin genes |
| T17413 |
36127-36136 |
Protein |
denotes |
ɛy globin |
| T17414 |
36138-36145 |
Protein |
denotes |
MHB1666 |
| T17415 |
36218-36226 |
Protein |
denotes |
ζ globin |
| T17416 |
36228-36235 |
Protein |
denotes |
MHB1668 |
| T17417 |
36307-36317 |
Protein |
denotes |
βH1 globin |
| T17418 |
36397-36412 |
Protein |
denotes |
βmaj/min globin |
| T17419 |
36527-36530 |
Protein |
denotes |
ROX |
| T17420 |
36532-36535 |
Protein |
denotes |
Bio |
| T17421 |
36536-36539 |
Protein |
denotes |
Rad |
| T17422 |
36800-36810 |
Protein |
denotes |
GAPDH mRNA |
| T17423 |
37103-37108 |
Protein |
denotes |
GAPDH |
| T17952 |
37224-37273 |
Protein |
denotes |
murine ɛy globin nucleotides 509–584; βmaj globin |
| T17953 |
37305-37309 |
Protein |
denotes |
Sox6 |
| T17954 |
37777-37784 |
Protein |
denotes |
SPOT RT |
| T18302 |
38507-38518 |
Protein |
denotes |
hematoxylin |
| T18303 |
38523-38528 |
Protein |
denotes |
eosin |
| T18569 |
38980-38984 |
Protein |
denotes |
Sox6 |
| T18894 |
39909-39916 |
Protein |
denotes |
FuGENE6 |
| T18895 |
40067-40071 |
Protein |
denotes |
Sox6 |
| T19250 |
40298-40302 |
Protein |
denotes |
Sox6 |
| T19251 |
40429-40433 |
Protein |
denotes |
Sox6 |
| T19252 |
40486-40491 |
Protein |
denotes |
c-Myc |
| T19253 |
40496-40498 |
Protein |
denotes |
HA |
| T19254 |
40704-40724 |
Protein |
denotes |
Sox6 coding sequence |
| T19512 |
40781-40785 |
Protein |
denotes |
Sox6 |
| T19513 |
41021-41025 |
Protein |
denotes |
Sox6 |
| T19514 |
41064-41078 |
Protein |
denotes |
c-Myc antibody |
| T19515 |
41117-41136 |
Protein |
denotes |
rabbit IgG antibody |
| T19683 |
41323-41347 |
Protein |
denotes |
T4 polynucleotide kinase |
| T19684 |
41444-41448 |
Protein |
denotes |
Sox6 |
| T19685 |
42192-42197 |
Protein |
denotes |
c-Myc |
| T19686 |
42199-42201 |
Protein |
denotes |
HA |
| T19687 |
42207-42211 |
Protein |
denotes |
Sox6 |
| T20375 |
43388-43392 |
Protein |
denotes |
Sox6 |
| T20376 |
43430-43433 |
Protein |
denotes |
IgG |
| T20377 |
43517-43535 |
Protein |
denotes |
chromatin-antibody |
| R11461 |
T16493 |
T16497 |
themeOf |
XhoI,contained |
| R11462 |
T16494 |
T16498 |
themeOf |
HindIII sites,contained |
| R11463 |
T16502 |
T16503 |
themeOf |
luciferase,expression |
| R11464 |
T16508 |
T16510 |
themeOf |
Sox6,overexpress |
| R11465 |
T16509 |
T16511 |
themeOf |
Sox6,overexpress |
| R11466 |
T16510 |
T16512 |
themeOf |
overexpress,overexpress |
| R11467 |
T16511 |
T16513 |
themeOf |
overexpress,overexpress |
| R11468 |
T16516 |
T16517 |
themeOf |
HMG domain,lacks |
| R25 |
T198 |
T201 |
causeOf |
Sox6,Silences |
| R26 |
T199 |
T200 |
themeOf |
Epsilon Globin,Expression |
| R27 |
T200 |
T201 |
themeOf |
Expression,Silences |
| R28 |
T202 |
T206 |
themeOf |
Sox6,defined |
| R29 |
T203 |
T207 |
themeOf |
Sox transcription factor family,defined |
| R30 |
T204 |
T205 |
partOf |
Sry,domain |
| R3091 |
T4494 |
T4496 |
themeOf |
Embryonic Globin,Expression |
| R3092 |
T4495 |
T4497 |
themeOf |
Sox6,Deficient |
| R3093 |
T4498 |
T4500 |
themeOf |
globin gene,upregulated |
| R3094 |
T4502 |
T4504 |
themeOf |
globin genes,expression |
| R3095 |
T4503 |
T4505 |
themeOf |
p100H,expression |
| R3096 |
T4507 |
T4508 |
themeOf |
adult β globin,expression |
| R3097 |
T4509 |
T4510 |
themeOf |
globin,expression |
| R3098 |
T4511 |
T4512 |
themeOf |
WT mice,expression |
| R31 |
T205 |
T206 |
Site |
domain,defined |
| R32 |
T205 |
T207 |
Site |
domain,defined |
| R33 |
T209 |
T212 |
themeOf |
Sox6,deficient |
| R34 |
T210 |
T213 |
themeOf |
p100H,expressed |
| R35 |
T211 |
T214 |
themeOf |
ɛy globin,expressed |
| R36 |
T216 |
T218 |
themeOf |
Sox6,binding |
| R37 |
T217 |
T218 |
Site |
promoter,binding |
| R38 |
T219 |
T222 |
themeOf |
Sox6,expression |
| R39 |
T223 |
T227 |
causeOf |
Sox6,required |
| R3938 |
T5701 |
T5702 |
partOf |
Sox6,Promoter |
| R3939 |
T5705 |
T5707 |
themeOf |
beta globins,expresses |
| R3940 |
T5710 |
T5712 |
themeOf |
Sox6,Overexpression |
| R3941 |
T5711 |
T5714 |
themeOf |
E-Luc reporter,repression |
| R3942 |
T5712 |
T5713 |
themeOf |
Overexpression,Overexpression |
| R3943 |
T5713 |
T5714 |
causeOf |
Overexpression,repression |
| R3944 |
T5715 |
T5719 |
themeOf |
Sox6,overexpression |
| R3945 |
T5716 |
T5721 |
partOf |
HMG,domain |
| R3946 |
T5719 |
T5720 |
themeOf |
overexpression,overexpression |
| R3947 |
T5723 |
T5726 |
themeOf |
Sox6,interact |
| R3948 |
T5723 |
T5727 |
themeOf |
Sox6,interact |
| R3949 |
T5724 |
T5726 |
themeOf |
CtBP2,interact |
| R3950 |
T5724 |
T5728 |
themeOf |
CtBP2,expressed |
| R3951 |
T5725 |
T5727 |
themeOf |
fgf-3 promoter [5],interact |
| R3952 |
T5729 |
T5730 |
themeOf |
CtBP2,expressed |
| R3953 |
T5731 |
T5736 |
themeOf |
CtBP2,interaction |
| R3954 |
T5732 |
T5737 |
themeOf |
Sox6,repression |
| R3955 |
T5734 |
T5738 |
themeOf |
Sox6,interaction |
| R3956 |
T5735 |
T5738 |
themeOf |
CtBP2,interaction |
| R3957 |
T5736 |
T5739 |
causeOf |
interaction,required |
| R3958 |
T5737 |
T5739 |
themeOf |
repression,required |
| R3959 |
T5738 |
T5740 |
themeOf |
interaction,abolish |
| R3960 |
T5746 |
T5747 |
themeOf |
Sox6,repression |
| R40 |
T224 |
T226 |
themeOf |
globin,silencing |
| R41 |
T228 |
T230 |
themeOf |
Sox6,regulation |
| R445 |
T226 |
T227 |
themeOf |
silencing,required |
| R4983 |
T7341 |
T7343 |
themeOf |
Sox6,Binds |
| R4984 |
T7342 |
T7343 |
Site |
Promoter,Binds |
| R4985 |
T7345 |
T7347 |
themeOf |
Sox6,associated |
| R4986 |
T7352 |
T7353 |
themeOf |
Sox6,associate |
| R4987 |
T7358 |
T7360 |
themeOf |
Myc,binds |
| R4988 |
T7361 |
T7362 |
themeOf |
adult β globins,express |
| R4989 |
T7363 |
T7364 |
themeOf |
Sox6,binds |
| R4990 |
T7365 |
T7367 |
themeOf |
Sox,binding |
| R4991 |
T7366 |
T7368 |
themeOf |
Sox6,binding |
| R4992 |
T7367 |
T7369 |
themeOf |
binding,required |
| R4993 |
T7368 |
T7370 |
themeOf |
binding,required |
| R4994 |
T7371 |
T7373 |
themeOf |
Sox,compete |
| R4995 |
T7372 |
T7374 |
themeOf |
Sox6,compete |
| R4996 |
T7373 |
T7375 |
themeOf |
compete,abolish |
| R4997 |
T7374 |
T7376 |
themeOf |
compete,abolish |
| R4998 |
T7377 |
T7378 |
themeOf |
WT,binding |
| R4999 |
T7388 |
T7390 |
themeOf |
Sox6,binds |
| R5000 |
T7389 |
T7390 |
Site |
promoter,binds |
| R5001 |
T7395 |
T7396 |
themeOf |
Sox6,binding |
| R6262 |
T9094 |
T9096 |
themeOf |
Globin,Expression |
| R6263 |
T9095 |
T9097 |
themeOf |
Sox6,Deficient |
| R6264 |
T9098 |
T9099 |
themeOf |
ɛy globin gene,expressed |
| R6265 |
T9098 |
T9100 |
themeOf |
ɛy globin gene,silenced |
| R6266 |
T9101 |
T9104 |
themeOf |
ɛy globin,expression |
| R6267 |
T9102 |
T9106 |
themeOf |
globin,expression |
| R6268 |
T9104 |
T9105 |
themeOf |
expression,due |
| R6269 |
T9107 |
T9108 |
themeOf |
ɛy globin,expressed |
| R6270 |
T9109 |
T9110 |
themeOf |
ɛy mRNA,expression |
| R6271 |
T9111 |
T9113 |
themeOf |
globin,expression |
| R6774 |
T9835 |
T9836 |
themeOf |
Sox6,Expression |
| R6775 |
T9837 |
T9840 |
themeOf |
Sox6,deficient |
| R6776 |
T9838 |
T9841 |
themeOf |
globin,express |
| R6777 |
T9842 |
T9843 |
themeOf |
Sox6,expression |
| R6778 |
T9845 |
T9846 |
themeOf |
Sox6,transcribed |
| R6779 |
T9847 |
T9848 |
themeOf |
Sox6,expression |
| R6780 |
T9849 |
T9851 |
themeOf |
ɛy globin,expressed |
| R7294 |
T10511 |
T10513 |
themeOf |
ɛy globin gene,silencing |
| R753 |
T1500 |
T1504 |
themeOf |
Sry type HMG box,member |
| R754 |
T1501 |
T1503 |
themeOf |
Sox6,member |
| R755 |
T1501 |
T1505 |
themeOf |
Sox6,member |
| R756 |
T1502 |
T1504 |
themeOf |
Sox transcription factor family,member |
| R757 |
T1502 |
T1505 |
themeOf |
Sox transcription factor family,member |
| R758 |
T1506 |
T1507 |
themeOf |
Sox,bind |
| R759 |
T1511 |
T1516 |
themeOf |
Sox6,Depletion |
| R760 |
T1512 |
T1517 |
themeOf |
HMG domain,expression |
| R761 |
T1513 |
T1518 |
themeOf |
Sox6,expression |
| R762 |
T1514 |
T1519 |
themeOf |
Sox9,expression |
| R763 |
T1515 |
T1520 |
themeOf |
Sry,expression |
| R764 |
T1526 |
T1527 |
themeOf |
Sox6 gene,disrupts |
| R765 |
T1531 |
T1535 |
themeOf |
Sry,bind |
| R766 |
T1533 |
T1536 |
themeOf |
HMG1,expressed |
| R767 |
T1534 |
T1537 |
themeOf |
HMG2 proteins,expressed |
| R7679 |
T11601 |
T11602 |
themeOf |
globin genes,regulation |
| R768 |
T1539 |
T1541 |
causeOf |
HMG proteins,modulate |
| R7680 |
T11604 |
T11607 |
causeOf |
globin genes,effect |
| R7681 |
T11605 |
T11606 |
themeOf |
ɛy globin gene,upregulation |
| R7682 |
T11606 |
T11607 |
themeOf |
upregulation,effect |
| R7683 |
T11608 |
T11612 |
themeOf |
Sox6,binds |
| R7684 |
T11609 |
T11611 |
themeOf |
ɛy-globin gene,represses |
| R7685 |
T11610 |
T11612 |
Site |
promoter,binds |
| R7686 |
T11620 |
T11621 |
themeOf |
Sox6,binds |
| R7687 |
T11622 |
T11626 |
themeOf |
group D Sox proteins,harbor |
| R7688 |
T11623 |
T11627 |
themeOf |
Sox6,harbor |
| R7689 |
T11625 |
T11628 |
themeOf |
D-Sox protein,binding |
| R769 |
T1540 |
T1541 |
themeOf |
β-globin,modulate |
| R770 |
T1543 |
T1544 |
themeOf |
β-globin genes,expressed |
| R771 |
T1546 |
T1547 |
themeOf |
adult β globins,express |
| R772 |
T1548 |
T1549 |
themeOf |
ɛ globin,silencing |
| R773 |
T1550 |
T1553 |
themeOf |
γ-globin,controlled |
| R774 |
T1550 |
T1552 |
partOf |
γ-globin,switch |
| R775 |
T1551 |
T1554 |
themeOf |
adult β-globin,controlled |
| R776 |
T1551 |
T1552 |
partOf |
adult β-globin,switch |
| R777 |
T1552 |
T1553 |
Site |
switch,controlled |
| R778 |
T1552 |
T1554 |
Site |
switch,controlled |
| R779 |
T1555 |
T1556 |
themeOf |
ɛ globin gene,silencing |
| R780 |
T1558 |
T1560 |
themeOf |
YY-1,bind |
| R781 |
T1561 |
T1562 |
themeOf |
Sox6,upregulated |
| R782 |
T1564 |
T1565 |
themeOf |
globin genes,expression |
| R783 |
T1566 |
T1567 |
themeOf |
globin gene,expression |
| R784 |
T1568 |
T1570 |
causeOf |
Sox6,effects |
| R785 |
T1569 |
T1570 |
themeOf |
ɛy globin gene,effects |
| R786 |
T1571 |
T1575 |
themeOf |
Sox6,binds |
| R787 |
T1571 |
T1576 |
themeOf |
Sox6,binds |
| R788 |
T1571 |
T1577 |
causeOf |
Sox6,represses |
| R789 |
T1572 |
T1574 |
themeOf |
ɛy globin,transcription |
| R790 |
T1572 |
T1576 |
themeOf |
ɛy globin,binds |
| R791 |
T1572 |
T1573 |
partOf |
ɛy globin,promoter |
| R792 |
T1573 |
T1575 |
Site |
promoter,binds |
| R793 |
T1573 |
T1576 |
Site |
promoter,binds |
| R794 |
T1574 |
T1577 |
themeOf |
transcription,represses |
| R795 |
T1578 |
T1580 |
themeOf |
Sox6,expressed |
| R796 |
T1578 |
T1581 |
themeOf |
Sox6,expressed |
| R797 |
T1579 |
T1582 |
themeOf |
ɛy globin,expressed |
| R798 |
T1579 |
T1583 |
themeOf |
ɛy globin,expression |
| R799 |
T1585 |
T1587 |
themeOf |
ɛy globin,absence |
| R9118 |
T13247 |
T13285 |
themeOf |
Sox6,binding |
| R9124 |
T13248 |
T13285 |
Site |
promoter,binding |
| R9147 |
T13285 |
T13421 |
themeOf |
binding,repression |
| R9148 |
T13285 |
T13422 |
themeOf |
binding,essential |
| R9199 |
T13423 |
T13425 |
themeOf |
Sox6,binds |
| R9200 |
T13423 |
T13426 |
themeOf |
Sox6,homodimer |
| R9201 |
T13423 |
T13427 |
themeOf |
Sox6,homodimer |
| R9202 |
T13423 |
T13428 |
themeOf |
Sox6,heterodimer |
| R9203 |
T13424 |
T13427 |
themeOf |
Sox proteins,homodimer |
| R9204 |
T13424 |
T13428 |
themeOf |
Sox proteins,heterodimer |
| R9205 |
T13429 |
T13430 |
themeOf |
Sox,interactions |
| R9207 |
T13433 |
T13436 |
themeOf |
globin repressors,bind |
| R9212 |
T13437 |
T13438 |
themeOf |
Sox6,interact |
| R9217 |
T13440 |
T13441 |
themeOf |
Sox,bind |
| R9219 |
T13440 |
T13442 |
themeOf |
Sox,bind |
| R9220 |
T13444 |
T13445 |
themeOf |
Sox6,binding |
| R9221 |
T13444 |
T13446 |
themeOf |
Sox6,binding |
| R9223 |
T13447 |
T13448 |
themeOf |
EKLF,binding |
| R9224 |
T13449 |
T13454 |
themeOf |
HMG,bind |
| R9225 |
T13449 |
T13455 |
themeOf |
HMG,bind |
| R9226 |
T13453 |
T13455 |
themeOf |
β globin silencers,bind |
| R9227 |
T13456 |
T13459 |
themeOf |
Sox6,expression |
| R9228 |
T13457 |
T13461 |
causeOf |
Sox6,represses |
| R9230 |
T13458 |
T13460 |
themeOf |
ɛy globin,expression |
| R9232 |
T13460 |
T13461 |
themeOf |
expression,represses |
| R9233 |
T13462 |
T13463 |
themeOf |
ɛy globin,expression |
| R9235 |
T13463 |
T13464 |
themeOf |
expression,due |
| R9237 |
T13465 |
T13468 |
causeOf |
Sox6,silence |
| R9238 |
T13466 |
T13467 |
themeOf |
globin,expression |
| R9239 |
T13467 |
T13468 |
themeOf |
expression,silence |
| R9240 |
T13469 |
T13471 |
themeOf |
ɛy globin,expression |
| R9242 |
T13472 |
T13473 |
themeOf |
globin gene,expression |
| R9243 |
T13474 |
T13478 |
themeOf |
globin genes,expression |
| R9244 |
T13475 |
T13479 |
themeOf |
ζ and βh1,expression |
| R9245 |
T13478 |
T13480 |
themeOf |
expression,levels |
| R9246 |
T13479 |
T13481 |
themeOf |
expression,levels |
| R9247 |
T13483 |
T13484 |
themeOf |
ɛy globin,expression |
| R9250 |
T13487 |
T13489 |
themeOf |
globin gene,expression |
| R9251 |
T13488 |
T13490 |
themeOf |
ɛy globin,levels |
| R9252 |
T13491 |
T13493 |
themeOf |
ζ and βh1 RNA,undetectable |
| R9253 |
T13492 |
T13494 |
themeOf |
globin RNA,elevated |
| R9255 |
T13495 |
T13500 |
causeOf |
Sox6,silence |
| R9257 |
T13496 |
T13498 |
themeOf |
globin,expression |
| R9258 |
T13497 |
T13499 |
themeOf |
ɛy-globin,regulation |
| R9259 |
T13498 |
T13500 |
themeOf |
expression,silence |
| R9262 |
T13501 |
T13503 |
causeOf |
Sox6,regulates |
| R9263 |
T13502 |
T13503 |
themeOf |
globin genes,regulates |
| R9266 |
T13507 |
T13510 |
themeOf |
Sox6,deficient |
| R9267 |
T13508 |
T13511 |
themeOf |
Sox proteins,expressed |
| R9270 |
T13514 |
T13516 |
themeOf |
human ɛ-globin,reactivation |
| R9272 |
T13515 |
T13517 |
themeOf |
ɛ-globin,silencing |
| R9274 |
T13518 |
T13520 |
themeOf |
Sox6,binds |
| R9275 |
T13519 |
T13520 |
Site |
promoter,binds |
| R9277 |
T13522 |
T13525 |
causeOf |
Sox6,important |
| R9279 |
T13523 |
T13524 |
themeOf |
human ɛ globin,silencing |
| R9280 |
T13524 |
T13525 |
themeOf |
silencing,important |
| R9282 |
T13530 |
T13531 |
themeOf |
ɛ globin,regulation |
