bionlp-ost-19-BB-norm-test  

BB-norm@ldeleger:BB-norm-23895665 JSONTXT

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Id Subject Object Predicate Lexical cue
T1 0-163 Title denotes Comparison of laboratory costs of rapid molecular tests and conventional diagnostics for detection of tuberculosis and drug-resistant tuberculosis in South Africa.
T6 14-24 Habitat denotes laboratory
T7 119-133 Phenotype denotes drug-resistant
T2 164-537 Paragraph denotes The World Health Organization has endorsed the use of molecular methods for the detection of TB and drug-resistant TB as a rapid alternative to culture-based systems. In South Africa, the Xpert MTB/Rif assay and the GenoType MTBDRplus have been implemented into reference laboratories for diagnosis of TB and drug-resistance, but their costs have not been fully elucidated.
T8 264-278 Phenotype denotes drug-resistant
T9 358-361 Microorganism denotes MTB
T10 436-448 Habitat denotes laboratories
T11 473-488 Phenotype denotes drug-resistance
T3 538-873 Paragraph denotes We conducted a detailed reference laboratory cost analysis of new rapid molecular assays (Xpert and MTBDRplus) for tuberculosis testing and drug-resistance testing in South Africa, and compared with the costs of conventional approaches involving sputum microscopy, liquid mycobacterial culture, and phenotypic drug sensitivity testing.
T12 572-582 Habitat denotes laboratory
T13 678-693 Phenotype denotes drug-resistance
T14 784-790 Habitat denotes sputum
T15 803-831 Habitat denotes liquid mycobacterial culture
T16 848-864 Phenotype denotes drug sensitivity
T4 874-1171 Paragraph denotes From a laboratory perspective, Xpert MTB/RIF cost $14.93/sample and the MTBDRplus line probe assay cost $23.46/sample, compared to $16.88/sample using conventional automated liquid culture-based methods. Laboratory costs of Xpert and MTBDRplus were most influenced by cost of consumables (60-80%).
T17 881-891 Habitat denotes laboratory
T18 911-914 Microorganism denotes MTB
T19 1048-1062 Habitat denotes liquid culture
T20 1078-1088 Habitat denotes Laboratory
T5 1172-1440 Paragraph denotes At current public sector pricing, Xpert MTB/RIF and MTBDRplus are comparable in cost to mycobacterial culture and conventional drug sensitivity testing. Overall, reference laboratories must balance costs with performance characteristics and the need for rapid results.
T21 1212-1215 Microorganism denotes MTB
T22 1260-1281 Habitat denotes mycobacterial culture
T23 1299-1315 Phenotype denotes drug sensitivity
T24 1344-1356 Habitat denotes laboratories