LitCovid-sentences  

PMC:7113610 / 10983-12504 JSONTXT 13 Projects

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Id Subject Object Predicate Lexical cue
T86 0-286 Sentence denotes SARS-CoV-2 possesses the typical coronavirus structure with spike protein and also expressed other polyproteins, nucleoproteins, and membrane proteins, such as RNA polymerase, 3-chymotrypsin-like protease, papain-like protease, helicase, glycoprotein, and accessory proteins [30], [31].
T87 287-404 Sentence denotes The spike protein of SARS-CoV-2 contains a 3-D structure in the RBD region to maintain the van der Waals forces [32].
T88 405-543 Sentence denotes The 394 glutamine residue in the RBD region of SARS-CoV-2 is recognized by the critical lysine 31 residue on the human ACE2 receptor [33].
T89 544-657 Sentence denotes The entire mechanism of pathogenicity of SARS-CoV-2, from attachment to replication is well mentioned in Fig. 3 .
T90 658-782 Sentence denotes Fig. 3 The life cycle of SARS-CoV-2 in host cells; begins its life cycle when S protein binds to the cellular receptor ACE2.
T91 783-935 Sentence denotes After receptor binding, the conformation change in the S protein facilitates viral envelope fusion with the cell membrane through the endosomal pathway.
T92 936-984 Sentence denotes Then SARS-CoV-2 releases RNA into the host cell.
T93 985-1122 Sentence denotes Genome RNA is translated into viral replicase polyproteins pp1a and 1ab, which are then cleaved into small products by viral proteinases.
T94 1123-1259 Sentence denotes The polymerase produces a series of subgenomic mRNAs by discontinuous transcription and finally translated into relevant viral proteins.
T95 1260-1413 Sentence denotes Viral proteins and genome RNA are subsequently assembled into virions in the ER and Golgi and then transported via vesicles and released out of the cell.
T96 1414-1521 Sentence denotes ACE2, angiotensin-converting enzyme 2; ER, endoplasmic reticulum; ERGIC, ER–Golgi intermediate compartment.