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PubMed:17450505 JSONTXT

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Id Subject Object Predicate Lexical cue
T1 0-124 Sentence denotes Effect of essential oils and isolated compounds from Pimpinella species on NF-kappaB: a target for antiinflammatory therapy.
T1 0-124 Sentence denotes Effect of essential oils and isolated compounds from Pimpinella species on NF-kappaB: a target for antiinflammatory therapy.
T2 125-275 Sentence denotes Pimpinella essential oils and isolated compounds were screened for their inhibitory activity against NF-kappaB mediated transcription in SW1353 cells.
T2 125-275 Sentence denotes Pimpinella essential oils and isolated compounds were screened for their inhibitory activity against NF-kappaB mediated transcription in SW1353 cells.
T3 276-350 Sentence denotes Twelve oils were effective in inhibiting NF-kappaB mediated transcription.
T3 276-350 Sentence denotes Twelve oils were effective in inhibiting NF-kappaB mediated transcription.
T4 351-498 Sentence denotes Especially the roots of P. corymbosa, P. tragium and P. rhodanta showed potent activities with IC(50) values of 2, 3 and 6 microg/mL, respectively.
T4 351-498 Sentence denotes Especially the roots of P. corymbosa, P. tragium and P. rhodanta showed potent activities with IC(50) values of 2, 3 and 6 microg/mL, respectively.
T5 499-864 Sentence denotes Five pure compounds, 7 (4-(2-propenyl)phenylangelate), 12 (4-(3-methyloxiranyl)phenyltiglate), 17 (4-methoxy-2-(3-methyloxiranyl)phenyl isobutyrate), 18 (4-methoxy-2-(3-methyloxiranyl)phenylangelate) and 21 (epoxy pseudoisoeugenol-2-methylbutyrate) inhibited NF-kappaB mediated transcription with IC(50) values of 5.5, 1.2, 0.01, 3.6 and 11 microg/mL, respectively.
T5 499-864 Sentence denotes Five pure compounds, 7 (4-(2-propenyl)phenylangelate), 12 (4-(3-methyloxiranyl)phenyltiglate), 17 (4-methoxy-2-(3-methyloxiranyl)phenyl isobutyrate), 18 (4-methoxy-2-(3-methyloxiranyl)phenylangelate) and 21 (epoxy pseudoisoeugenol-2-methylbutyrate) inhibited NF-kappaB mediated transcription with IC(50) values of 5.5, 1.2, 0.01, 3.6 and 11 microg/mL, respectively.
T6 865-921 Sentence denotes None of the compounds were cytotoxic to mammalian cells.
T6 865-921 Sentence denotes None of the compounds were cytotoxic to mammalian cells.
T7 922-1119 Sentence denotes These findings add significant information to the pharmacological activity of Pimpinella species and their beneficial effects and use in disease prevention especially those related to inflammation.
T7 922-1119 Sentence denotes These findings add significant information to the pharmacological activity of Pimpinella species and their beneficial effects and use in disease prevention especially those related to inflammation.