SeeDev-binary@ldeleger:SeeDev-binary-21330492-4
Annnotations
{"target":"http://pubannotation.org/docs/sourcedb/SeeDev-binary@ldeleger/sourceid/SeeDev-binary-21330492-4","sourcedb":"SeeDev-binary@ldeleger","sourceid":"SeeDev-binary-21330492-4","text":"The key positive regulators of the maturation program are the LEC genes, probably assisted by several bZIP and MYB transcription\nfactors (Baud et al., 2008). All of these bind to the promoters of seed storage protein genes and genes involved in the synthesis of storage lipids\n(Lara et al., 2003; Kagaya et al., 2005; Braybrook et al., 2006; Santos-Mendoza et al., 2008). We found that several of these genes were up-regulated in the dcl1-15 mutant: FUS3, LEC2, L1L, and several MYBs and bZIPs (Table I). In contrast, ABI3 was unaffected and LEC1 was down-regulated.\nWe observed that in the wild type, the FUS3 and LEC2 transcriptional reporter genes are excluded from the embryo proper until the early heart stage, just before the beginning\nof maturation. In dcl1-15, they are expressed in the embryo proper at least by the early globular stage, coinciding with the onset of chlorophyll accumulation\nin the mutant. Our analysis of lec2-1 dcl1-15 and fus3-3 dcl1-15 double mutants confirms that both proteins are required for the early maturation phenotype, further supporting their position\ndownstream of miRNAs.\n","tracks":[{"project":"bionlp-ost-19-SeeDev-bin-train","denotations":[{"id":"T1","span":{"begin":35,"end":53},"obj":"Regulatory_Network"},{"id":"T2","span":{"begin":35,"end":45},"obj":"Development_Phase"},{"id":"T3","span":{"begin":62,"end":71},"obj":"Gene_Family"},{"id":"T4","span":{"begin":62,"end":65},"obj":"Protein_Family"},{"id":"T5-0","span":{"begin":102,"end":106},"obj":"_FRAGMENT"},{"id":"T5-1","span":{"begin":115,"end":136},"obj":"Protein_Family"},{"id":"T6","span":{"begin":111,"end":136},"obj":"Protein_Family"},{"id":"T7","span":{"begin":183,"end":222},"obj":"Promoter"},{"id":"T8-0","span":{"begin":183,"end":195},"obj":"_FRAGMENT"},{"id":"T8-1","span":{"begin":227,"end":276},"obj":"Promoter"},{"id":"T9","span":{"begin":196,"end":216},"obj":"Pathway"},{"id":"T10","span":{"begin":196,"end":200},"obj":"Tissue"},{"id":"T11","span":{"begin":249,"end":276},"obj":"Pathway"},{"id":"T12","span":{"begin":434,"end":441},"obj":"Genotype"},{"id":"T13","span":{"begin":450,"end":454},"obj":"Gene"},{"id":"T14","span":{"begin":456,"end":460},"obj":"Gene"},{"id":"T15","span":{"begin":462,"end":465},"obj":"Gene"},{"id":"T16","span":{"begin":479,"end":483},"obj":"Protein_Family"},{"id":"T17","span":{"begin":488,"end":493},"obj":"Protein_Family"},{"id":"T18","span":{"begin":518,"end":522},"obj":"Gene"},{"id":"T19","span":{"begin":518,"end":522},"obj":"Gene_Family"},{"id":"T20","span":{"begin":542,"end":546},"obj":"Gene"},{"id":"T21","span":{"begin":591,"end":600},"obj":"Genotype"},{"id":"T22","span":{"begin":606,"end":610},"obj":"Gene"},{"id":"T23","span":{"begin":615,"end":619},"obj":"Gene"},{"id":"T24","span":{"begin":673,"end":686},"obj":"Tissue"},{"id":"T25","span":{"begin":687,"end":714},"obj":"Development_Phase"},{"id":"T26","span":{"begin":721,"end":755},"obj":"Development_Phase"},{"id":"T27","span":{"begin":760,"end":767},"obj":"Genotype"},{"id":"T28","span":{"begin":795,"end":808},"obj":"Tissue"},{"id":"T29","span":{"begin":825,"end":845},"obj":"Development_Phase"},{"id":"T30","span":{"begin":876,"end":900},"obj":"Pathway"},{"id":"T31","span":{"begin":908,"end":914},"obj":"Genotype"},{"id":"T32","span":{"begin":932,"end":946},"obj":"Genotype"},{"id":"T33","span":{"begin":951,"end":965},"obj":"Genotype"},{"id":"T34","span":{"begin":1030,"end":1046},"obj":"Development_Phase"},{"id":"T35","span":{"begin":1106,"end":1112},"obj":"RNA"},{"id":"E1","span":{"begin":434,"end":441},"obj":"Regulates_Expression"},{"id":"E2","span":{"begin":434,"end":441},"obj":"Regulates_Expression"},{"id":"E3","span":{"begin":795,"end":808},"obj":"Regulates_Expression"},{"id":"E4","span":{"begin":434,"end":441},"obj":"Regulates_Expression"},{"id":"E5","span":{"begin":673,"end":686},"obj":"Regulates_Expression"},{"id":"E6","span":{"begin":434,"end":441},"obj":"Regulates_Expression"},{"id":"E7","span":{"begin":434,"end":441},"obj":"Regulates_Expression"},{"id":"E8","span":{"begin":673,"end":686},"obj":"Regulates_Expression"},{"id":"E9","span":{"begin":795,"end":808},"obj":"Regulates_Expression"},{"id":"E10-0","span":{"begin":102,"end":106},"obj":"_FRAGMENT"},{"id":"E10-1","span":{"begin":115,"end":136},"obj":"Regulates_Process"},{"id":"E11","span":{"begin":111,"end":136},"obj":"Regulates_Process"},{"id":"E12","span":{"begin":62,"end":71},"obj":"Regulates_Process"},{"id":"E13","span":{"begin":62,"end":65},"obj":"Binds_To"},{"id":"E14-0","span":{"begin":102,"end":106},"obj":"_FRAGMENT"},{"id":"E14-1","span":{"begin":115,"end":136},"obj":"Binds_To"},{"id":"E15-0","span":{"begin":102,"end":106},"obj":"_FRAGMENT"},{"id":"E15-1","span":{"begin":115,"end":136},"obj":"Binds_To"},{"id":"E16","span":{"begin":62,"end":65},"obj":"Binds_To"},{"id":"E17","span":{"begin":111,"end":136},"obj":"Binds_To"},{"id":"E18","span":{"begin":111,"end":136},"obj":"Binds_To"},{"id":"E19","span":{"begin":721,"end":755},"obj":"Regulates_Expression"},{"id":"E20","span":{"begin":825,"end":845},"obj":"Regulates_Expression"},{"id":"E21","span":{"begin":721,"end":755},"obj":"Regulates_Expression"},{"id":"E22","span":{"begin":760,"end":767},"obj":"Regulates_Expression"},{"id":"E23","span":{"begin":591,"end":600},"obj":"Regulates_Expression"},{"id":"E24","span":{"begin":687,"end":714},"obj":"Regulates_Expression"},{"id":"E25","span":{"begin":591,"end":600},"obj":"Regulates_Expression"},{"id":"E26","span":{"begin":687,"end":714},"obj":"Regulates_Expression"},{"id":"E27","span":{"begin":825,"end":845},"obj":"Regulates_Expression"},{"id":"E28","span":{"begin":760,"end":767},"obj":"Regulates_Expression"}],"relations":[{"id":"R1","pred":"Agent","subj":"E1","obj":"T12"},{"id":"R2","pred":"DNA","subj":"E1","obj":"T20"},{"id":"R3","pred":"Agent","subj":"E2","obj":"T12"},{"id":"R4","pred":"DNA","subj":"E2","obj":"T13"},{"id":"R5","pred":"Agent","subj":"E3","obj":"T28"},{"id":"R6","pred":"DNA","subj":"E3","obj":"T22"},{"id":"R7","pred":"Agent","subj":"E4","obj":"T12"},{"id":"R8","pred":"DNA","subj":"E4","obj":"T18"},{"id":"R9","pred":"Agent","subj":"E5","obj":"T24"},{"id":"R10","pred":"DNA","subj":"E5","obj":"T23"},{"id":"R11","pred":"Agent","subj":"E6","obj":"T12"},{"id":"R12","pred":"DNA","subj":"E6","obj":"T15"},{"id":"R13","pred":"Agent","subj":"E7","obj":"T12"},{"id":"R14","pred":"DNA","subj":"E7","obj":"T14"},{"id":"R15","pred":"Agent","subj":"E8","obj":"T24"},{"id":"R16","pred":"DNA","subj":"E8","obj":"T22"},{"id":"R17","pred":"Agent","subj":"E9","obj":"T28"},{"id":"R18","pred":"DNA","subj":"E9","obj":"T23"},{"id":"R19","pred":"Agent","subj":"E10-0","obj":"T5-0"},{"id":"R20","pred":"Process","subj":"E10-0","obj":"T1"},{"id":"R21","pred":"Agent","subj":"E11","obj":"T6"},{"id":"R22","pred":"Process","subj":"E11","obj":"T1"},{"id":"R23","pred":"Agent","subj":"E12","obj":"T3"},{"id":"R24","pred":"Process","subj":"E12","obj":"T1"},{"id":"R25","pred":"Functional_Molecule","subj":"E13","obj":"T4"},{"id":"R26","pred":"Molecule","subj":"E13","obj":"T8-0"},{"id":"R27","pred":"Functional_Molecule","subj":"E14-0","obj":"T5-0"},{"id":"R28","pred":"Molecule","subj":"E14-0","obj":"T8-0"},{"id":"R29","pred":"Functional_Molecule","subj":"E15-0","obj":"T5-0"},{"id":"R30","pred":"Molecule","subj":"E15-0","obj":"T7"},{"id":"R31","pred":"Functional_Molecule","subj":"E16","obj":"T4"},{"id":"R32","pred":"Molecule","subj":"E16","obj":"T7"},{"id":"R33","pred":"Functional_Molecule","subj":"E17","obj":"T6"},{"id":"R34","pred":"Molecule","subj":"E17","obj":"T8-0"},{"id":"R35","pred":"Functional_Molecule","subj":"E18","obj":"T6"},{"id":"R36","pred":"Molecule","subj":"E18","obj":"T7"},{"id":"R37","pred":"Agent","subj":"E19","obj":"T26"},{"id":"R38","pred":"DNA","subj":"E19","obj":"T22"},{"id":"R39","pred":"Agent","subj":"E20","obj":"T29"},{"id":"R40","pred":"DNA","subj":"E20","obj":"T22"},{"id":"R41","pred":"Agent","subj":"E21","obj":"T26"},{"id":"R42","pred":"DNA","subj":"E21","obj":"T23"},{"id":"R43","pred":"Agent","subj":"E22","obj":"T27"},{"id":"R44","pred":"DNA","subj":"E22","obj":"T22"},{"id":"R45","pred":"Agent","subj":"E23","obj":"T21"},{"id":"R46","pred":"DNA","subj":"E23","obj":"T23"},{"id":"R47","pred":"Agent","subj":"E24","obj":"T25"},{"id":"R48","pred":"DNA","subj":"E24","obj":"T23"},{"id":"R49","pred":"Agent","subj":"E25","obj":"T21"},{"id":"R50","pred":"DNA","subj":"E25","obj":"T22"},{"id":"R51","pred":"Agent","subj":"E26","obj":"T25"},{"id":"R52","pred":"DNA","subj":"E26","obj":"T22"},{"id":"R53","pred":"Agent","subj":"E27","obj":"T29"},{"id":"R54","pred":"DNA","subj":"E27","obj":"T23"},{"id":"R55","pred":"Agent","subj":"E28","obj":"T27"},{"id":"R56","pred":"DNA","subj":"E28","obj":"T23"},{"id":"C-T5-0","pred":"_lexicallyChainedTo","subj":"T5-1","obj":"T5-0"},{"id":"C-T8-0","pred":"_lexicallyChainedTo","subj":"T8-1","obj":"T8-0"},{"id":"C-E10-0","pred":"_lexicallyChainedTo","subj":"E10-1","obj":"E10-0"},{"id":"C-E14-0","pred":"_lexicallyChainedTo","subj":"E14-1","obj":"E14-0"},{"id":"C-E15-0","pred":"_lexicallyChainedTo","subj":"E15-1","obj":"E15-0"}],"attributes":[{"subj":"T1","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T2","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T3","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T4","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T5-0","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T5-1","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T6","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T7","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T8-0","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T8-1","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T9","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T10","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T11","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T12","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T13","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T14","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T15","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T16","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T17","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T18","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T19","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T20","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T21","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T22","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T23","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T24","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T25","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T26","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T27","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T28","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T29","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T30","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T31","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T32","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T33","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T34","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"T35","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E1","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E2","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E3","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E4","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E5","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E6","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E7","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E8","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E9","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E10-0","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E10-1","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E11","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E12","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E13","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E14-0","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E14-1","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E15-0","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E15-1","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E16","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E17","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E18","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E19","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E20","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E21","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E22","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E23","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E24","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E25","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E26","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E27","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"},{"subj":"E28","pred":"source","obj":"bionlp-ost-19-SeeDev-bin-train"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"bionlp-ost-19-SeeDev-bin-train","color":"#93a0ec","default":true}]}]}}