PubMed:22969303 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PubMed/sourceid/22969303","sourcedb":"PubMed","sourceid":"22969303","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/22969303","text":"Epstein-Barr virus-positive ileal extraosseous plasmacytoma containing plasmablastic lymphoma components with CD20-positive lymph node involvement.\nWe report a case of Epstein-Barr virus (EBV)-positive ileal extraosseous plasmacytoma containing plasmablastic lymphoma components with CD20-positive lymph node involvement. A 34-year-old healthy Japanese male developed intussusception due to an ileal plasmacytoma. The lesion was positive for EBV-encoded small nuclear RNA in in situ hybridization, with the surrounding lymph nodes showing the expression of CD20. Tumor cells in the ileal and lymph node lesions contained high-grade malignant features compatible with plasmablastic lymphoma. Because his abdominal lymph nodes recurred 6 months after resection, he received six cycles of R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone), and had a complete remission. Although his case was complicated by acute promyelocytic leukemia, he has so far survived, recurrence-free, for more than 7.5 years after chemotherapy for extraosseous plasmacytoma.","tracks":[{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":221,"end":233},"obj":"HP_0011857"},{"id":"T2","span":{"begin":259,"end":267},"obj":"HP_0002665"},{"id":"T3","span":{"begin":298,"end":320},"obj":"HP_0002733"},{"id":"T4","span":{"begin":368,"end":383},"obj":"HP_0002576"},{"id":"T5","span":{"begin":400,"end":412},"obj":"HP_0011857"},{"id":"T6","span":{"begin":563,"end":568},"obj":"HP_0002664"},{"id":"T7","span":{"begin":681,"end":689},"obj":"HP_0002665"},{"id":"T8","span":{"begin":948,"end":976},"obj":"HP_0004836"},{"id":"T9","span":{"begin":968,"end":976},"obj":"HP_0001909"},{"id":"T10","span":{"begin":1079,"end":1091},"obj":"HP_0011857"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"},{"subj":"T4","pred":"source","obj":"PubmedHPO"},{"subj":"T5","pred":"source","obj":"PubmedHPO"},{"subj":"T6","pred":"source","obj":"PubmedHPO"},{"subj":"T7","pred":"source","obj":"PubmedHPO"},{"subj":"T8","pred":"source","obj":"PubmedHPO"},{"subj":"T9","pred":"source","obj":"PubmedHPO"},{"subj":"T10","pred":"source","obj":"PubmedHPO"}]},{"project":"Allie","denotations":[{"id":"SS1_22969303_1_0","span":{"begin":168,"end":186},"obj":"expanded"},{"id":"SS2_22969303_1_0","span":{"begin":188,"end":191},"obj":"abbr"}],"relations":[{"id":"AE1_22969303_1_0","pred":"abbreviatedTo","subj":"SS1_22969303_1_0","obj":"SS2_22969303_1_0"}],"attributes":[{"subj":"SS1_22969303_1_0","pred":"source","obj":"Allie"},{"subj":"SS2_22969303_1_0","pred":"source","obj":"Allie"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubmedHPO","color":"#ecdd93","default":true},{"id":"Allie","color":"#c393ec"}]}]}}