| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-143 |
Sentence |
denotes |
Transient pseudo-hypoaldosteronism following resection of the ileum: normal level of lymphocytic aldosterone receptors outside the acute phase. |
| T1 |
0-143 |
Sentence |
denotes |
Transient pseudo-hypoaldosteronism following resection of the ileum: normal level of lymphocytic aldosterone receptors outside the acute phase. |
| TextSentencer_T2 |
144-302 |
Sentence |
denotes |
Pseudo-hypoaldosteronism (PHA) is due to mineralocorticoid resistance and manifests as hyponatremia and hyperkalemia with increased plasma aldosterone levels. |
| T2 |
144-302 |
Sentence |
denotes |
Pseudo-hypoaldosteronism (PHA) is due to mineralocorticoid resistance and manifests as hyponatremia and hyperkalemia with increased plasma aldosterone levels. |
| TextSentencer_T3 |
303-369 |
Sentence |
denotes |
It may be familial or secondary to abnormal renal sodium handling. |
| T3 |
303-369 |
Sentence |
denotes |
It may be familial or secondary to abnormal renal sodium handling. |
| TextSentencer_T4 |
370-525 |
Sentence |
denotes |
We report the case of a 54-year-old woman with multifocal cancer of the colon, who developed PHA after subtotal colectomy, ileal resection and jejunostomy. |
| T4 |
370-525 |
Sentence |
denotes |
We report the case of a 54-year-old woman with multifocal cancer of the colon, who developed PHA after subtotal colectomy, ileal resection and jejunostomy. |
| TextSentencer_T5 |
526-647 |
Sentence |
denotes |
She was treated with 6 g of salt daily to prevent dehydration, which she stopped herself because of reduced fecal losses. |
| T5 |
526-647 |
Sentence |
denotes |
She was treated with 6 g of salt daily to prevent dehydration, which she stopped herself because of reduced fecal losses. |
| TextSentencer_T6 |
648-984 |
Sentence |
denotes |
One month later she was admitted with signs of acute adrenal failure, i.e. fatigue, severe nausea, blood pressure of 80/60 mmHg, extracellular dehydration, hyponatremia (118 mmol/l); hyperkalemia (7.6 mmol/l), increased blood urea nitrogen (BUN) (200 mg/dl) and creatininemia (2.5 mg/dl), and decreased plasma bicarbonates level (HCO3-: |
| T6 |
648-984 |
Sentence |
denotes |
One month later she was admitted with signs of acute adrenal failure, i.e. fatigue, severe nausea, blood pressure of 80/60 mmHg, extracellular dehydration, hyponatremia (118 mmol/l); hyperkalemia (7.6 mmol/l), increased blood urea nitrogen (BUN) (200 mg/dl) and creatininemia (2.5 mg/dl), and decreased plasma bicarbonates level (HCO3-: |
| TextSentencer_T7 |
985-998 |
Sentence |
denotes |
16 mmol/l; N: |
| T7 |
985-998 |
Sentence |
denotes |
16 mmol/l; N: |
| TextSentencer_T8 |
999-1006 |
Sentence |
denotes |
27-30). |
| T8 |
999-1006 |
Sentence |
denotes |
27-30). |
| TextSentencer_T9 |
1007-1077 |
Sentence |
denotes |
However, the plasma cortisol was high (66 microg/100 ml at 10:00 h; N: |
| T9 |
1007-1077 |
Sentence |
denotes |
However, the plasma cortisol was high (66 microg/100 ml at 10:00 h; N: |
| TextSentencer_T10 |
1078-1121 |
Sentence |
denotes |
8-15) and the ACTH was normal (13 pg/ml, N: |
| T10 |
1078-1121 |
Sentence |
denotes |
8-15) and the ACTH was normal (13 pg/ml, N: |
| TextSentencer_T11 |
1122-1245 |
Sentence |
denotes |
10-60); there was a marked increase in plasma renin activity (>37 ng/ml/h; N supine <3), active renin (869 pg/ml; N supine: |
| T11 |
1122-1245 |
Sentence |
denotes |
10-60); there was a marked increase in plasma renin activity (>37 ng/ml/h; N supine <3), active renin (869 pg/ml; N supine: |
| TextSentencer_T12 |
1246-1324 |
Sentence |
denotes |
1.120), aldosterone (>2000 pg/ml; N supine <150) and plasma AVP (20 pmol/l; N: |
| T12 |
1246-1324 |
Sentence |
denotes |
1.120), aldosterone (>2000 pg/ml; N supine <150) and plasma AVP (20 pmol/l; N: |
| TextSentencer_T13 |
1325-1334 |
Sentence |
denotes |
0.5-2.5). |
| T13 |
1325-1334 |
Sentence |
denotes |
0.5-2.5). |
| TextSentencer_T14 |
1335-1380 |
Sentence |
denotes |
The plasma ANH level was 38 pmol/l (N supine: |
| T14 |
1335-1380 |
Sentence |
denotes |
The plasma ANH level was 38 pmol/l (N supine: |
| TextSentencer_T15 |
1381-1387 |
Sentence |
denotes |
5-25). |
| T15 |
1381-1387 |
Sentence |
denotes |
5-25). |
| TextSentencer_T16 |
1388-1463 |
Sentence |
denotes |
A urinary steroidogram resulted in highly elevated tetrahydrocortisol (THF: |
| T16 |
1388-1463 |
Sentence |
denotes |
A urinary steroidogram resulted in highly elevated tetrahydrocortisol (THF: |
| TextSentencer_T17 |
1464-1479 |
Sentence |
denotes |
13.3 mg/24h; N: |
| T17 |
1464-1479 |
Sentence |
denotes |
13.3 mg/24h; N: |
| TextSentencer_T18 |
1480-1536 |
Sentence |
denotes |
1.4+/-0.8) with no increase in tetrahydrocortisone (THE: |
| T18 |
1480-1536 |
Sentence |
denotes |
1.4+/-0.8) with no increase in tetrahydrocortisone (THE: |
| TextSentencer_T19 |
1537-1552 |
Sentence |
denotes |
3.16 mg/24h; N: |
| T19 |
1537-1552 |
Sentence |
denotes |
3.16 mg/24h; N: |
| TextSentencer_T20 |
1553-1605 |
Sentence |
denotes |
2.7+/-2.0) excretion, and with low THE/THF (0.24; N: |
| T20 |
1553-1605 |
Sentence |
denotes |
2.7+/-2.0) excretion, and with low THE/THF (0.24; N: |
| TextSentencer_T21 |
1606-1646 |
Sentence |
denotes |
1.87+/-0.36) and alpha THF/THF (0.35; N: |
| T21 |
1606-1646 |
Sentence |
denotes |
1.87+/-0.36) and alpha THF/THF (0.35; N: |
| TextSentencer_T22 |
1647-1667 |
Sentence |
denotes |
0.92+/-0.42) ratios. |
| T22 |
1647-1667 |
Sentence |
denotes |
0.92+/-0.42) ratios. |
| TextSentencer_T23 |
1668-1832 |
Sentence |
denotes |
The number of mineralocorticoid receptors in mononuclear leukocytes was in the lower normal range for age, while the number of glucocorticoid receptors was reduced. |
| T23 |
1668-1832 |
Sentence |
denotes |
The number of mineralocorticoid receptors in mononuclear leukocytes was in the lower normal range for age, while the number of glucocorticoid receptors was reduced. |
| TextSentencer_T24 |
1833-2035 |
Sentence |
denotes |
Small-bowel resection in ileostomized patients causes excessive fecal sodium losses and results in chronic sodium depletion with contraction of the plasma volume and severe secondary hyperaldosteronism. |
| T24 |
1833-2035 |
Sentence |
denotes |
Small-bowel resection in ileostomized patients causes excessive fecal sodium losses and results in chronic sodium depletion with contraction of the plasma volume and severe secondary hyperaldosteronism. |
| TextSentencer_T25 |
2036-2216 |
Sentence |
denotes |
Nevertheless, this hyperaldosteronism may be associated with hyponatremia and hyperkalemia suggesting PHA related to the major importance of the colon for the absorption of sodium. |
| T25 |
2036-2216 |
Sentence |
denotes |
Nevertheless, this hyperaldosteronism may be associated with hyponatremia and hyperkalemia suggesting PHA related to the major importance of the colon for the absorption of sodium. |
| TextSentencer_T26 |
2217-2645 |
Sentence |
denotes |
In conclusion, this case report emphasizes 1) the possibility of a syndrome of acquired PHA with severe hyperkalemia after resection of the ileum and colon responding to oral salt supplementation; 2) the major increase in AVP and the small increase in ANH; 3) the strong increase in urinary THF with low THE/THF and alpha THF/THF ratios; 4) the normal number of lymphocytic mineralocorticoid receptors outside the acute episode. |
| T26 |
2217-2645 |
Sentence |
denotes |
In conclusion, this case report emphasizes 1) the possibility of a syndrome of acquired PHA with severe hyperkalemia after resection of the ileum and colon responding to oral salt supplementation; 2) the major increase in AVP and the small increase in ANH; 3) the strong increase in urinary THF with low THE/THF and alpha THF/THF ratios; 4) the normal number of lymphocytic mineralocorticoid receptors outside the acute episode. |