Id |
Subject |
Object |
Predicate |
Lexical cue |
T3 |
4-20 |
PosReg |
denotes |
gain-of-function |
T2 |
30-34 |
Var |
denotes |
E76K |
T1 |
38-42 |
Gene |
denotes |
SHP2 |
T4 |
43-51 |
PosReg |
denotes |
promotes |
T36 |
52-55 |
Disease |
denotes |
CAC |
T37 |
56-69 |
CPA |
denotes |
tumorigenesis |
T10 |
74-81 |
PosReg |
denotes |
induces |
T11 |
82-85 |
CPA |
denotes |
EMT |
T42 |
94-125 |
Pathway |
denotes |
Wnt/β-catenin signaling pathway |
T38 |
340-348 |
Var |
denotes |
mutation |
T39 |
358-362 |
Gene |
denotes |
SHP2 |
T41 |
370-377 |
Reg |
denotes |
highest |
T40 |
382-399 |
Disease |
denotes |
colorectal cancer |
T23 |
977-983 |
Gene |
denotes |
Ptpn11 |
T24 |
983-987 |
Var |
denotes |
E76K |
T25 |
1024-1034 |
PosReg |
denotes |
aggravated |
T26 |
1035-1047 |
CPA |
denotes |
inflammation |
T27 |
1052-1061 |
PosReg |
denotes |
increased |
T28 |
1062-1065 |
Disease |
denotes |
CAC |
T29 |
1066-1079 |
CPA |
denotes |
tumorigenesis |
T30 |
1091-1095 |
Gene |
denotes |
SHP2 |
T31 |
1095-1099 |
Var |
denotes |
E76K |
T32 |
1111-1119 |
PosReg |
denotes |
promoted |
T33 |
1120-1163 |
CPA |
denotes |
malignant biological behaviors of CRC cells |
T34 |
1168-1175 |
PosReg |
denotes |
induced |
T35 |
1176-1215 |
CPA |
denotes |
epithelial-mesenchymal transition (EMT) |
T21 |
1291-1295 |
Gene |
denotes |
SHP2 |
T22 |
1295-1299 |
Var |
denotes |
E76K |
T17 |
1325-1333 |
PosReg |
denotes |
promotes |
T18 |
1338-1351 |
CPA |
denotes |
tumorigenesis |
T19 |
1356-1366 |
CPA |
denotes |
metastasis |
T20 |
1370-1373 |
Disease |
denotes |
CRC |
R1 |
T1 |
T2 |
ThemeOf |
SHP2,E76K |
R10 |
T24 |
T25 |
CauseOf |
E76K,aggravated |
R11 |
T26 |
T25 |
ThemeOf |
inflammation,aggravated |
R12 |
T24 |
T27 |
CauseOf |
E76K,increased |
R15 |
T30 |
T31 |
ThemeOf |
SHP2,E76K |
R16 |
T31 |
T32 |
CauseOf |
E76K,promoted |
R17 |
T31 |
T34 |
CauseOf |
E76K,induced |
R18 |
T33 |
T32 |
ThemeOf |
malignant biological behaviors of CRC cells,promoted |
R19 |
T35 |
T34 |
ThemeOf |
epithelial-mesenchymal transition (EMT),induced |
R2 |
T2 |
T3 |
CauseOf |
E76K,gain-of-function |
R20 |
T21 |
T22 |
ThemeOf |
SHP2,E76K |
R21 |
T22 |
T17 |
CauseOf |
E76K,promotes |
R22 |
T18 |
T17 |
ThemeOf |
tumorigenesis,promotes |
R23 |
T19 |
T17 |
ThemeOf |
metastasis,promotes |
R24 |
T20 |
T19 |
ThemeOf |
CRC,metastasis |
R25 |
T20 |
T18 |
ThemeOf |
CRC,tumorigenesis |
R26 |
T29 |
T27 |
ThemeOf |
tumorigenesis,increased |
R27 |
T28 |
T29 |
ThemeOf |
CAC,tumorigenesis |
R28 |
T36 |
T37 |
ThemeOf |
CAC,tumorigenesis |
R29 |
T37 |
T4 |
ThemeOf |
tumorigenesis,promotes |
R3 |
T3 |
T4 |
CauseOf |
gain-of-function,promotes |
R30 |
T39 |
T38 |
ThemeOf |
SHP2,mutation |
R31 |
T38 |
T41 |
CauseOf |
mutation,highest |
R32 |
T40 |
T41 |
ThemeOf |
colorectal cancer,highest |
R33 |
T42 |
T10 |
ThemeOf |
Wnt/β-catenin signaling pathway,induces |
R7 |
T11 |
T10 |
ThemeOf |
EMT,induces |
R8 |
T3 |
T10 |
CauseOf |
gain-of-function,induces |
R9 |
T23 |
T24 |
ThemeOf |
Ptpn11,E76K |