Id |
Subject |
Object |
Predicate |
Lexical cue |
T14505 |
0-7 |
NNS |
denotes |
Effects |
T14506 |
8-10 |
IN |
denotes |
of |
T14507 |
11-14 |
NN |
denotes |
K14 |
T14509 |
14-15 |
HYPH |
denotes |
- |
T14508 |
15-18 |
NN |
denotes |
cre |
T14511 |
18-19 |
HYPH |
denotes |
– |
T14510 |
19-25 |
VBN |
denotes |
Driven |
T14512 |
26-30 |
NN |
denotes |
Loss |
T14513 |
31-33 |
IN |
denotes |
of |
T14514 |
34-37 |
NN |
denotes |
Apc |
T14515 |
38-40 |
IN |
denotes |
in |
T14516 |
41-46 |
JJ |
denotes |
Other |
T14518 |
47-56 |
JJ |
denotes |
Epidermal |
T14517 |
57-67 |
NNS |
denotes |
Appendages |
T14519 |
67-268 |
sentence |
denotes |
Similar to the biology of hair follicles, K14-cre–driven loss of Apc also affected the development of other epidermal appendages that depend on epithelial–mesenchymal interactions for their formation. |
T14520 |
68-75 |
JJ |
denotes |
Similar |
T14522 |
76-78 |
IN |
denotes |
to |
T14523 |
79-82 |
DT |
denotes |
the |
T14524 |
83-90 |
NN |
denotes |
biology |
T14525 |
91-93 |
IN |
denotes |
of |
T14526 |
94-98 |
NN |
denotes |
hair |
T14527 |
99-108 |
NNS |
denotes |
follicles |
T14528 |
108-110 |
, |
denotes |
, |
T14529 |
110-113 |
NN |
denotes |
K14 |
T14531 |
113-114 |
HYPH |
denotes |
- |
T14530 |
114-117 |
NN |
denotes |
cre |
T14533 |
117-118 |
HYPH |
denotes |
– |
T14532 |
118-124 |
VBN |
denotes |
driven |
T14534 |
125-129 |
NN |
denotes |
loss |
T14535 |
130-132 |
IN |
denotes |
of |
T14536 |
133-136 |
NN |
denotes |
Apc |
T14537 |
137-141 |
RB |
denotes |
also |
T14521 |
142-150 |
VBD |
denotes |
affected |
T14538 |
151-154 |
DT |
denotes |
the |
T14539 |
155-166 |
NN |
denotes |
development |
T14540 |
167-169 |
IN |
denotes |
of |
T14541 |
170-175 |
JJ |
denotes |
other |
T14543 |
176-185 |
JJ |
denotes |
epidermal |
T14542 |
186-196 |
NNS |
denotes |
appendages |
T14544 |
197-201 |
WDT |
denotes |
that |
T14545 |
202-208 |
VBP |
denotes |
depend |
T14546 |
209-211 |
IN |
denotes |
on |
T14547 |
212-222 |
JJ |
denotes |
epithelial |
T14549 |
222-223 |
HYPH |
denotes |
– |
T14548 |
223-234 |
JJ |
denotes |
mesenchymal |
T14550 |
235-247 |
NNS |
denotes |
interactions |
T14551 |
248-251 |
IN |
denotes |
for |
T14552 |
252-257 |
PRP$ |
denotes |
their |
T14553 |
258-267 |
NN |
denotes |
formation |
T14554 |
267-268 |
. |
denotes |
. |
T14555 |
268-332 |
sentence |
denotes |
The most striking of these was dental dysplasia (Figure 4K–4R). |
T14556 |
269-272 |
DT |
denotes |
The |
T14558 |
273-277 |
RBS |
denotes |
most |
T14557 |
278-286 |
JJ |
denotes |
striking |
T14560 |
287-289 |
IN |
denotes |
of |
T14561 |
290-295 |
DT |
denotes |
these |
T14559 |
296-299 |
VBD |
denotes |
was |
T14562 |
300-306 |
JJ |
denotes |
dental |
T14563 |
307-316 |
NN |
denotes |
dysplasia |
T14564 |
317-318 |
-LRB- |
denotes |
( |
T14566 |
318-324 |
NN |
denotes |
Figure |
T14565 |
325-327 |
NN |
denotes |
4K |
T14567 |
327-328 |
SYM |
denotes |
– |
T14568 |
328-330 |
NN |
denotes |
4R |
T14569 |
330-331 |
-RRB- |
denotes |
) |
T14570 |
331-332 |
. |
denotes |
. |
T14571 |
332-534 |
sentence |
denotes |
Tooth development is normally initiated between E11 and E12 by invagination of ectodermally derived oral epithelium into the underlying cranial neural crest–derived mesenchyme, generating a tooth germ. |
T14572 |
333-338 |
NN |
denotes |
Tooth |
T14573 |
339-350 |
NN |
denotes |
development |
T14575 |
351-353 |
VBZ |
denotes |
is |
T14576 |
354-362 |
RB |
denotes |
normally |
T14574 |
363-372 |
VBN |
denotes |
initiated |
T14577 |
373-380 |
IN |
denotes |
between |
T14578 |
381-384 |
NN |
denotes |
E11 |
T14579 |
385-388 |
CC |
denotes |
and |
T14580 |
389-392 |
NN |
denotes |
E12 |
T14581 |
393-395 |
IN |
denotes |
by |
T14582 |
396-408 |
NN |
denotes |
invagination |
T14583 |
409-411 |
IN |
denotes |
of |
T14584 |
412-424 |
RB |
denotes |
ectodermally |
T14585 |
425-432 |
VBN |
denotes |
derived |
T14587 |
433-437 |
JJ |
denotes |
oral |
T14586 |
438-448 |
NN |
denotes |
epithelium |
T14588 |
449-453 |
IN |
denotes |
into |
T14589 |
454-457 |
DT |
denotes |
the |
T14591 |
458-468 |
VBG |
denotes |
underlying |
T14592 |
469-476 |
JJ |
denotes |
cranial |
T14594 |
477-483 |
JJ |
denotes |
neural |
T14593 |
484-489 |
NN |
denotes |
crest |
T14596 |
489-490 |
HYPH |
denotes |
– |
T14595 |
490-497 |
VBN |
denotes |
derived |
T14590 |
498-508 |
NN |
denotes |
mesenchyme |
T14597 |
508-510 |
, |
denotes |
, |
T14598 |
510-520 |
VBG |
denotes |
generating |
T14599 |
521-522 |
DT |
denotes |
a |
T14601 |
523-528 |
JJ |
denotes |
tooth |
T14600 |
529-533 |
NN |
denotes |
germ |
T14602 |
533-534 |
. |
denotes |
. |
T14603 |
534-698 |
sentence |
denotes |
Despite the grossly toothless phenotype of KA mutants, histological analysis of their oral cavities revealed the formation of multiple tooth buds at each location. |
T14604 |
535-542 |
IN |
denotes |
Despite |
T14606 |
543-546 |
DT |
denotes |
the |
T14608 |
547-554 |
RB |
denotes |
grossly |
T14609 |
555-564 |
JJ |
denotes |
toothless |
T14607 |
565-574 |
NN |
denotes |
phenotype |
T14610 |
575-577 |
IN |
denotes |
of |
T14611 |
578-580 |
NN |
denotes |
KA |
T14612 |
581-588 |
NNS |
denotes |
mutants |
T14613 |
588-590 |
, |
denotes |
, |
T14614 |
590-602 |
JJ |
denotes |
histological |
T14615 |
603-611 |
NN |
denotes |
analysis |
T14616 |
612-614 |
IN |
denotes |
of |
T14617 |
615-620 |
PRP$ |
denotes |
their |
T14619 |
621-625 |
JJ |
denotes |
oral |
T14618 |
626-634 |
NNS |
denotes |
cavities |
T14605 |
635-643 |
VBD |
denotes |
revealed |
T14620 |
644-647 |
DT |
denotes |
the |
T14621 |
648-657 |
NN |
denotes |
formation |
T14622 |
658-660 |
IN |
denotes |
of |
T14623 |
661-669 |
JJ |
denotes |
multiple |
T14625 |
670-675 |
JJ |
denotes |
tooth |
T14624 |
676-680 |
NNS |
denotes |
buds |
T14626 |
681-683 |
IN |
denotes |
at |
T14627 |
684-688 |
DT |
denotes |
each |
T14628 |
689-697 |
NN |
denotes |
location |
T14629 |
697-698 |
. |
denotes |
. |
T14630 |
698-803 |
sentence |
denotes |
These aberrant teeth obviously failed to grow out during the dietary transition from milk to solid food. |
T14631 |
699-704 |
DT |
denotes |
These |
T14633 |
705-713 |
JJ |
denotes |
aberrant |
T14632 |
714-719 |
NNS |
denotes |
teeth |
T14635 |
720-729 |
RB |
denotes |
obviously |
T14634 |
730-736 |
VBD |
denotes |
failed |
T14636 |
737-739 |
TO |
denotes |
to |
T14637 |
740-744 |
VB |
denotes |
grow |
T14638 |
745-748 |
RP |
denotes |
out |
T14639 |
749-755 |
IN |
denotes |
during |
T14640 |
756-759 |
DT |
denotes |
the |
T14642 |
760-767 |
JJ |
denotes |
dietary |
T14641 |
768-778 |
NN |
denotes |
transition |
T14643 |
779-783 |
IN |
denotes |
from |
T14644 |
784-788 |
NN |
denotes |
milk |
T14645 |
789-791 |
IN |
denotes |
to |
T14646 |
792-797 |
JJ |
denotes |
solid |
T14647 |
798-802 |
NN |
denotes |
food |
T14648 |
802-803 |
. |
denotes |
. |
T14649 |
803-1007 |
sentence |
denotes |
Analogous to the expression patterns of K14 and β-catenin in the normal skin, diffuse membrane-bound expression of β-catenin was detected in K14-expressing oral epithelium and ameloblasts of normal mice. |
T14650 |
804-813 |
JJ |
denotes |
Analogous |
T14652 |
814-816 |
IN |
denotes |
to |
T14653 |
817-820 |
DT |
denotes |
the |
T14655 |
821-831 |
NN |
denotes |
expression |
T14654 |
832-840 |
NNS |
denotes |
patterns |
T14656 |
841-843 |
IN |
denotes |
of |
T14657 |
844-847 |
NN |
denotes |
K14 |
T14658 |
848-851 |
CC |
denotes |
and |
T14659 |
852-853 |
NN |
denotes |
β |
T14661 |
853-854 |
HYPH |
denotes |
- |
T14660 |
854-861 |
NN |
denotes |
catenin |
T14662 |
862-864 |
IN |
denotes |
in |
T14663 |
865-868 |
DT |
denotes |
the |
T14665 |
869-875 |
JJ |
denotes |
normal |
T14664 |
876-880 |
NN |
denotes |
skin |
T14666 |
880-882 |
, |
denotes |
, |
T14667 |
882-889 |
JJ |
denotes |
diffuse |
T14669 |
890-898 |
NN |
denotes |
membrane |
T14671 |
898-899 |
HYPH |
denotes |
- |
T14670 |
899-904 |
VBN |
denotes |
bound |
T14668 |
905-915 |
NN |
denotes |
expression |
T14672 |
916-918 |
IN |
denotes |
of |
T14673 |
919-920 |
NN |
denotes |
β |
T14675 |
920-921 |
HYPH |
denotes |
- |
T14674 |
921-928 |
NN |
denotes |
catenin |
T14676 |
929-932 |
VBD |
denotes |
was |
T14651 |
933-941 |
VBN |
denotes |
detected |
T14677 |
942-944 |
IN |
denotes |
in |
T14678 |
945-948 |
NN |
denotes |
K14 |
T14680 |
948-949 |
HYPH |
denotes |
- |
T14679 |
949-959 |
VBG |
denotes |
expressing |
T14682 |
960-964 |
JJ |
denotes |
oral |
T14681 |
965-975 |
NN |
denotes |
epithelium |
T14683 |
976-979 |
CC |
denotes |
and |
T14684 |
980-991 |
NNS |
denotes |
ameloblasts |
T14685 |
992-994 |
IN |
denotes |
of |
T14686 |
995-1001 |
JJ |
denotes |
normal |
T14687 |
1002-1006 |
NNS |
denotes |
mice |
T14688 |
1006-1007 |
. |
denotes |
. |
T14689 |
1007-1166 |
sentence |
denotes |
In mutants, some of the K14-expressing cells also showed strong cytosolic/nuclear β-catenin staining, as observed in the mutant skin (Figure 4Q, 4Q′, and 4R). |
T14690 |
1008-1010 |
IN |
denotes |
In |
T14692 |
1011-1018 |
NNS |
denotes |
mutants |
T14693 |
1018-1020 |
, |
denotes |
, |
T14694 |
1020-1024 |
DT |
denotes |
some |
T14695 |
1025-1027 |
IN |
denotes |
of |
T14696 |
1028-1031 |
DT |
denotes |
the |
T14698 |
1032-1035 |
NN |
denotes |
K14 |
T14700 |
1035-1036 |
HYPH |
denotes |
- |
T14699 |
1036-1046 |
VBG |
denotes |
expressing |
T14697 |
1047-1052 |
NNS |
denotes |
cells |
T14701 |
1053-1057 |
RB |
denotes |
also |
T14691 |
1058-1064 |
VBD |
denotes |
showed |
T14702 |
1065-1071 |
JJ |
denotes |
strong |
T14704 |
1072-1081 |
JJ |
denotes |
cytosolic |
T14706 |
1081-1082 |
HYPH |
denotes |
/ |
T14707 |
1082-1089 |
JJ |
denotes |
nuclear |
T14705 |
1090-1091 |
NN |
denotes |
β |
T14708 |
1091-1092 |
HYPH |
denotes |
- |
T14709 |
1092-1099 |
NN |
denotes |
catenin |
T14703 |
1100-1108 |
NN |
denotes |
staining |
T14710 |
1108-1110 |
, |
denotes |
, |
T14711 |
1110-1112 |
IN |
denotes |
as |
T14712 |
1113-1121 |
VBN |
denotes |
observed |
T14713 |
1122-1124 |
IN |
denotes |
in |
T14714 |
1125-1128 |
DT |
denotes |
the |
T14716 |
1129-1135 |
JJ |
denotes |
mutant |
T14715 |
1136-1140 |
NN |
denotes |
skin |
T14717 |
1141-1142 |
-LRB- |
denotes |
( |
T14719 |
1142-1148 |
NN |
denotes |
Figure |
T14718 |
1149-1151 |
NN |
denotes |
4Q |
T14720 |
1151-1153 |
, |
denotes |
, |
T14721 |
1153-1155 |
NN |
denotes |
4Q |
T14722 |
1155-1156 |
SYM |
denotes |
′ |
T14723 |
1156-1158 |
, |
denotes |
, |
T14724 |
1158-1161 |
CC |
denotes |
and |
T14725 |
1162-1164 |
NN |
denotes |
4R |
T14726 |
1164-1165 |
-RRB- |
denotes |
) |
T14727 |
1165-1166 |
. |
denotes |
. |
T14728 |
1166-1319 |
sentence |
denotes |
Initiation of ectopic tooth buds in the mutant mice was evident at E15.5 by extra dots of Shh expression adjacent to the primary teeth (data not shown). |
T14729 |
1167-1177 |
NN |
denotes |
Initiation |
T14731 |
1178-1180 |
IN |
denotes |
of |
T14732 |
1181-1188 |
JJ |
denotes |
ectopic |
T14734 |
1189-1194 |
JJ |
denotes |
tooth |
T14733 |
1195-1199 |
NNS |
denotes |
buds |
T14735 |
1200-1202 |
IN |
denotes |
in |
T14736 |
1203-1206 |
DT |
denotes |
the |
T14738 |
1207-1213 |
JJ |
denotes |
mutant |
T14737 |
1214-1218 |
NNS |
denotes |
mice |
T14730 |
1219-1222 |
VBD |
denotes |
was |
T14739 |
1223-1230 |
JJ |
denotes |
evident |
T14740 |
1231-1233 |
IN |
denotes |
at |
T14741 |
1234-1239 |
NN |
denotes |
E15.5 |
T14742 |
1240-1242 |
IN |
denotes |
by |
T14743 |
1243-1248 |
JJ |
denotes |
extra |
T14744 |
1249-1253 |
NNS |
denotes |
dots |
T14745 |
1254-1256 |
IN |
denotes |
of |
T14746 |
1257-1260 |
NN |
denotes |
Shh |
T14747 |
1261-1271 |
NN |
denotes |
expression |
T14748 |
1272-1280 |
JJ |
denotes |
adjacent |
T14749 |
1281-1283 |
IN |
denotes |
to |
T14750 |
1284-1287 |
DT |
denotes |
the |
T14752 |
1288-1295 |
JJ |
denotes |
primary |
T14751 |
1296-1301 |
NNS |
denotes |
teeth |
T14753 |
1302-1303 |
-LRB- |
denotes |
( |
T14755 |
1303-1307 |
NNS |
denotes |
data |
T14756 |
1308-1311 |
RB |
denotes |
not |
T14754 |
1312-1317 |
VBN |
denotes |
shown |
T14757 |
1317-1318 |
-RRB- |
denotes |
) |
T14758 |
1318-1319 |
. |
denotes |
. |
T14759 |
1319-1447 |
sentence |
denotes |
Loss of Apc also leads to hyperplasia in squamous epithelia of cornea, oral, salivary, and Hardarian glands (unpublished data). |
T14760 |
1320-1324 |
NN |
denotes |
Loss |
T14762 |
1325-1327 |
IN |
denotes |
of |
T14763 |
1328-1331 |
NN |
denotes |
Apc |
T14764 |
1332-1336 |
RB |
denotes |
also |
T14761 |
1337-1342 |
VBZ |
denotes |
leads |
T14765 |
1343-1345 |
IN |
denotes |
to |
T14766 |
1346-1357 |
NN |
denotes |
hyperplasia |
T14767 |
1358-1360 |
IN |
denotes |
in |
T14768 |
1361-1369 |
JJ |
denotes |
squamous |
T14769 |
1370-1379 |
NNS |
denotes |
epithelia |
T14770 |
1380-1382 |
IN |
denotes |
of |
T14771 |
1383-1389 |
NN |
denotes |
cornea |
T14773 |
1389-1391 |
, |
denotes |
, |
T14774 |
1391-1395 |
JJ |
denotes |
oral |
T14775 |
1395-1397 |
, |
denotes |
, |
T14776 |
1397-1405 |
JJ |
denotes |
salivary |
T14777 |
1405-1407 |
, |
denotes |
, |
T14778 |
1407-1410 |
CC |
denotes |
and |
T14779 |
1411-1420 |
JJ |
denotes |
Hardarian |
T14772 |
1421-1427 |
NNS |
denotes |
glands |
T14780 |
1428-1429 |
-LRB- |
denotes |
( |
T14782 |
1429-1440 |
JJ |
denotes |
unpublished |
T14781 |
1441-1445 |
NNS |
denotes |
data |
T14783 |
1445-1446 |
-RRB- |
denotes |
) |
T14784 |
1446-1447 |
. |
denotes |
. |
T14785 |
1447-1575 |
sentence |
denotes |
Squamous metaplasia to hair follicle–like structures, ectopic hair follicle morphogenesis was also observed in these epithelia. |
T14786 |
1448-1456 |
JJ |
denotes |
Squamous |
T14787 |
1457-1467 |
NN |
denotes |
metaplasia |
T14789 |
1468-1470 |
IN |
denotes |
to |
T14790 |
1471-1475 |
NN |
denotes |
hair |
T14791 |
1476-1484 |
NN |
denotes |
follicle |
T14793 |
1484-1485 |
HYPH |
denotes |
– |
T14792 |
1485-1489 |
JJ |
denotes |
like |
T14794 |
1490-1500 |
NNS |
denotes |
structures |
T14795 |
1500-1502 |
, |
denotes |
, |
T14796 |
1502-1509 |
JJ |
denotes |
ectopic |
T14798 |
1510-1514 |
NN |
denotes |
hair |
T14799 |
1515-1523 |
NN |
denotes |
follicle |
T14797 |
1524-1537 |
NN |
denotes |
morphogenesis |
T14800 |
1538-1541 |
VBD |
denotes |
was |
T14801 |
1542-1546 |
RB |
denotes |
also |
T14788 |
1547-1555 |
VBN |
denotes |
observed |
T14802 |
1556-1558 |
IN |
denotes |
in |
T14803 |
1559-1564 |
DT |
denotes |
these |
T14804 |
1565-1574 |
NNS |
denotes |
epithelia |
T14805 |
1574-1575 |
. |
denotes |
. |
R4273 |
T14506 |
T14505 |
prep |
of,Effects |
R4274 |
T14507 |
T14508 |
compound |
K14,cre |
R4275 |
T14508 |
T14510 |
npadvmod |
cre,Driven |
R4276 |
T14509 |
T14508 |
punct |
-,cre |
R4277 |
T14510 |
T14512 |
amod |
Driven,Loss |
R4278 |
T14511 |
T14510 |
punct |
–,Driven |
R4279 |
T14512 |
T14506 |
pobj |
Loss,of |
R4280 |
T14513 |
T14512 |
prep |
of,Loss |
R4281 |
T14514 |
T14513 |
pobj |
Apc,of |
R4282 |
T14515 |
T14505 |
prep |
in,Effects |
R4283 |
T14516 |
T14517 |
amod |
Other,Appendages |
R4284 |
T14517 |
T14515 |
pobj |
Appendages,in |
R4285 |
T14518 |
T14517 |
amod |
Epidermal,Appendages |
R4286 |
T14520 |
T14521 |
advcl |
Similar,affected |
R4287 |
T14522 |
T14520 |
prep |
to,Similar |
R4288 |
T14523 |
T14524 |
det |
the,biology |
R4289 |
T14524 |
T14522 |
pobj |
biology,to |
R4290 |
T14525 |
T14524 |
prep |
of,biology |
R4291 |
T14526 |
T14527 |
compound |
hair,follicles |
R4292 |
T14527 |
T14525 |
pobj |
follicles,of |
R4293 |
T14528 |
T14521 |
punct |
", ",affected |
R4294 |
T14529 |
T14530 |
compound |
K14,cre |
R4295 |
T14530 |
T14532 |
npadvmod |
cre,driven |
R4296 |
T14531 |
T14530 |
punct |
-,cre |
R4297 |
T14532 |
T14534 |
amod |
driven,loss |
R4298 |
T14533 |
T14532 |
punct |
–,driven |
R4299 |
T14534 |
T14521 |
nsubj |
loss,affected |
R4300 |
T14535 |
T14534 |
prep |
of,loss |
R4301 |
T14536 |
T14535 |
pobj |
Apc,of |
R4302 |
T14537 |
T14521 |
advmod |
also,affected |
R4303 |
T14538 |
T14539 |
det |
the,development |
R4304 |
T14539 |
T14521 |
dobj |
development,affected |
R4305 |
T14540 |
T14539 |
prep |
of,development |
R4306 |
T14541 |
T14542 |
amod |
other,appendages |
R4307 |
T14542 |
T14540 |
pobj |
appendages,of |
R4308 |
T14543 |
T14542 |
amod |
epidermal,appendages |
R4309 |
T14544 |
T14545 |
dep |
that,depend |
R4310 |
T14545 |
T14542 |
relcl |
depend,appendages |
R4311 |
T14546 |
T14545 |
prep |
on,depend |
R4312 |
T14547 |
T14548 |
amod |
epithelial,mesenchymal |
R4313 |
T14548 |
T14550 |
amod |
mesenchymal,interactions |
R4314 |
T14549 |
T14548 |
punct |
–,mesenchymal |
R4315 |
T14550 |
T14546 |
pobj |
interactions,on |
R4316 |
T14551 |
T14545 |
prep |
for,depend |
R4317 |
T14552 |
T14553 |
poss |
their,formation |
R4318 |
T14553 |
T14551 |
pobj |
formation,for |
R4319 |
T14554 |
T14521 |
punct |
.,affected |
R4320 |
T14556 |
T14557 |
det |
The,striking |
R4321 |
T14557 |
T14559 |
nsubj |
striking,was |
R4322 |
T14558 |
T14557 |
advmod |
most,striking |
R4323 |
T14560 |
T14557 |
prep |
of,striking |
R4324 |
T14561 |
T14560 |
pobj |
these,of |
R4325 |
T14562 |
T14563 |
amod |
dental,dysplasia |
R4326 |
T14563 |
T14559 |
attr |
dysplasia,was |
R4327 |
T14564 |
T14565 |
punct |
(,4K |
R4328 |
T14565 |
T14559 |
parataxis |
4K,was |
R4329 |
T14566 |
T14565 |
compound |
Figure,4K |
R4330 |
T14567 |
T14568 |
punct |
–,4R |
R4331 |
T14568 |
T14565 |
prep |
4R,4K |
R4332 |
T14569 |
T14565 |
punct |
),4K |
R4333 |
T14570 |
T14559 |
punct |
.,was |
R4334 |
T14572 |
T14573 |
compound |
Tooth,development |
R4335 |
T14573 |
T14574 |
nsubjpass |
development,initiated |
R4336 |
T14575 |
T14574 |
auxpass |
is,initiated |
R4337 |
T14576 |
T14574 |
advmod |
normally,initiated |
R4338 |
T14577 |
T14574 |
prep |
between,initiated |
R4339 |
T14578 |
T14577 |
pobj |
E11,between |
R4340 |
T14579 |
T14578 |
cc |
and,E11 |
R4341 |
T14580 |
T14578 |
conj |
E12,E11 |
R4342 |
T14581 |
T14574 |
prep |
by,initiated |
R4343 |
T14582 |
T14581 |
pobj |
invagination,by |
R4344 |
T14583 |
T14582 |
prep |
of,invagination |
R4345 |
T14584 |
T14585 |
advmod |
ectodermally,derived |
R4346 |
T14585 |
T14586 |
amod |
derived,epithelium |
R4347 |
T14586 |
T14583 |
pobj |
epithelium,of |
R4348 |
T14587 |
T14586 |
amod |
oral,epithelium |
R4349 |
T14588 |
T14582 |
prep |
into,invagination |
R4350 |
T14589 |
T14590 |
det |
the,mesenchyme |
R4351 |
T14590 |
T14588 |
pobj |
mesenchyme,into |
R4352 |
T14591 |
T14590 |
amod |
underlying,mesenchyme |
R4353 |
T14592 |
T14593 |
amod |
cranial,crest |
R4354 |
T14593 |
T14595 |
npadvmod |
crest,derived |
R4355 |
T14594 |
T14593 |
amod |
neural,crest |
R4356 |
T14595 |
T14590 |
amod |
derived,mesenchyme |
R4357 |
T14596 |
T14595 |
punct |
–,derived |
R4358 |
T14597 |
T14574 |
punct |
", ",initiated |
R4359 |
T14598 |
T14574 |
advcl |
generating,initiated |
R4360 |
T14599 |
T14600 |
det |
a,germ |
R4361 |
T14600 |
T14598 |
dobj |
germ,generating |
R4362 |
T14601 |
T14600 |
amod |
tooth,germ |
R4363 |
T14602 |
T14574 |
punct |
.,initiated |
R4364 |
T14604 |
T14605 |
prep |
Despite,revealed |
R4365 |
T14606 |
T14607 |
det |
the,phenotype |
R4366 |
T14607 |
T14604 |
pobj |
phenotype,Despite |
R4367 |
T14608 |
T14609 |
advmod |
grossly,toothless |
R4368 |
T14609 |
T14607 |
amod |
toothless,phenotype |
R4369 |
T14610 |
T14607 |
prep |
of,phenotype |
R4370 |
T14611 |
T14612 |
compound |
KA,mutants |
R4371 |
T14612 |
T14610 |
pobj |
mutants,of |
R4372 |
T14613 |
T14605 |
punct |
", ",revealed |
R4373 |
T14614 |
T14615 |
amod |
histological,analysis |
R4374 |
T14615 |
T14605 |
nsubj |
analysis,revealed |
R4375 |
T14616 |
T14615 |
prep |
of,analysis |
R4376 |
T14617 |
T14618 |
poss |
their,cavities |
R4377 |
T14618 |
T14616 |
pobj |
cavities,of |
R4378 |
T14619 |
T14618 |
amod |
oral,cavities |
R4379 |
T14620 |
T14621 |
det |
the,formation |
R4380 |
T14621 |
T14605 |
dobj |
formation,revealed |
R4381 |
T14622 |
T14621 |
prep |
of,formation |
R4382 |
T14623 |
T14624 |
amod |
multiple,buds |
R4383 |
T14624 |
T14622 |
pobj |
buds,of |
R4384 |
T14625 |
T14624 |
amod |
tooth,buds |
R4385 |
T14626 |
T14605 |
prep |
at,revealed |
R4386 |
T14627 |
T14628 |
det |
each,location |
R4387 |
T14628 |
T14626 |
pobj |
location,at |
R4388 |
T14629 |
T14605 |
punct |
.,revealed |
R4389 |
T14631 |
T14632 |
det |
These,teeth |
R4390 |
T14632 |
T14634 |
nsubj |
teeth,failed |
R4391 |
T14633 |
T14632 |
amod |
aberrant,teeth |
R4392 |
T14635 |
T14634 |
advmod |
obviously,failed |
R4393 |
T14636 |
T14637 |
aux |
to,grow |
R4394 |
T14637 |
T14634 |
xcomp |
grow,failed |
R4395 |
T14638 |
T14637 |
prt |
out,grow |
R4396 |
T14639 |
T14637 |
prep |
during,grow |
R4397 |
T14640 |
T14641 |
det |
the,transition |
R4398 |
T14641 |
T14639 |
pobj |
transition,during |
R4399 |
T14642 |
T14641 |
amod |
dietary,transition |
R4400 |
T14643 |
T14641 |
prep |
from,transition |
R4401 |
T14644 |
T14643 |
pobj |
milk,from |
R4402 |
T14645 |
T14641 |
prep |
to,transition |
R4403 |
T14646 |
T14647 |
amod |
solid,food |
R4404 |
T14647 |
T14645 |
pobj |
food,to |
R4405 |
T14648 |
T14634 |
punct |
.,failed |
R4406 |
T14650 |
T14651 |
advcl |
Analogous,detected |
R4407 |
T14652 |
T14650 |
prep |
to,Analogous |
R4408 |
T14653 |
T14654 |
det |
the,patterns |
R4409 |
T14654 |
T14652 |
pobj |
patterns,to |
R4410 |
T14655 |
T14654 |
compound |
expression,patterns |
R4411 |
T14656 |
T14654 |
prep |
of,patterns |
R4412 |
T14657 |
T14656 |
pobj |
K14,of |
R4413 |
T14658 |
T14657 |
cc |
and,K14 |
R4414 |
T14659 |
T14660 |
compound |
β,catenin |
R4415 |
T14660 |
T14657 |
conj |
catenin,K14 |
R4416 |
T14661 |
T14660 |
punct |
-,catenin |
R4417 |
T14662 |
T14654 |
prep |
in,patterns |
R4418 |
T14663 |
T14664 |
det |
the,skin |
R4419 |
T14664 |
T14662 |
pobj |
skin,in |
R4420 |
T14665 |
T14664 |
amod |
normal,skin |
R4421 |
T14666 |
T14651 |
punct |
", ",detected |
R4422 |
T14667 |
T14668 |
amod |
diffuse,expression |
R4423 |
T14668 |
T14651 |
nsubjpass |
expression,detected |
R4424 |
T14669 |
T14670 |
npadvmod |
membrane,bound |
R4425 |
T14670 |
T14668 |
amod |
bound,expression |
R4426 |
T14671 |
T14670 |
punct |
-,bound |
R4427 |
T14672 |
T14668 |
prep |
of,expression |
R4428 |
T14673 |
T14674 |
compound |
β,catenin |
R4429 |
T14674 |
T14672 |
pobj |
catenin,of |
R4430 |
T14675 |
T14674 |
punct |
-,catenin |
R4431 |
T14676 |
T14651 |
auxpass |
was,detected |
R4432 |
T14677 |
T14651 |
prep |
in,detected |
R4433 |
T14678 |
T14679 |
npadvmod |
K14,expressing |
R4434 |
T14679 |
T14681 |
amod |
expressing,epithelium |
R4435 |
T14680 |
T14679 |
punct |
-,expressing |
R4436 |
T14681 |
T14677 |
pobj |
epithelium,in |
R4437 |
T14682 |
T14681 |
amod |
oral,epithelium |
R4438 |
T14683 |
T14681 |
cc |
and,epithelium |
R4439 |
T14684 |
T14681 |
conj |
ameloblasts,epithelium |
R4440 |
T14685 |
T14681 |
prep |
of,epithelium |
R4441 |
T14686 |
T14687 |
amod |
normal,mice |
R4442 |
T14687 |
T14685 |
pobj |
mice,of |
R4443 |
T14688 |
T14651 |
punct |
.,detected |
R4444 |
T14690 |
T14691 |
prep |
In,showed |
R4445 |
T14692 |
T14690 |
pobj |
mutants,In |
R4446 |
T14693 |
T14691 |
punct |
", ",showed |
R4447 |
T14694 |
T14691 |
nsubj |
some,showed |
R4448 |
T14695 |
T14694 |
prep |
of,some |
R4449 |
T14696 |
T14697 |
det |
the,cells |
R4450 |
T14697 |
T14695 |
pobj |
cells,of |
R4451 |
T14698 |
T14699 |
npadvmod |
K14,expressing |
R4452 |
T14699 |
T14697 |
amod |
expressing,cells |
R4453 |
T14700 |
T14699 |
punct |
-,expressing |
R4454 |
T14701 |
T14691 |
advmod |
also,showed |
R4455 |
T14702 |
T14703 |
amod |
strong,staining |
R4456 |
T14703 |
T14691 |
dobj |
staining,showed |
R4457 |
T14704 |
T14705 |
amod |
cytosolic,β |
R4458 |
T14705 |
T14703 |
nmod |
β,staining |
R4459 |
T14706 |
T14705 |
punct |
/,β |
R4460 |
T14707 |
T14705 |
amod |
nuclear,β |
R4461 |
T14708 |
T14705 |
punct |
-,β |
R4462 |
T14709 |
T14705 |
appos |
catenin,β |
R4463 |
T14710 |
T14691 |
punct |
", ",showed |
R4464 |
T14711 |
T14712 |
mark |
as,observed |
R4465 |
T14712 |
T14691 |
advcl |
observed,showed |
R4466 |
T14713 |
T14712 |
prep |
in,observed |
R4467 |
T14714 |
T14715 |
det |
the,skin |
R4468 |
T14715 |
T14713 |
pobj |
skin,in |
R4469 |
T14716 |
T14715 |
amod |
mutant,skin |
R4470 |
T14717 |
T14718 |
punct |
(,4Q |
R4471 |
T14718 |
T14691 |
parataxis |
4Q,showed |
R4472 |
T14719 |
T14718 |
compound |
Figure,4Q |
R4473 |
T14720 |
T14718 |
punct |
", ",4Q |
R4474 |
T14721 |
T14718 |
conj |
4Q,4Q |
R4475 |
T14722 |
T14721 |
punct |
′,4Q |
R4476 |
T14723 |
T14721 |
punct |
", ",4Q |
R4477 |
T14724 |
T14721 |
cc |
and,4Q |
R4478 |
T14725 |
T14721 |
conj |
4R,4Q |
R4479 |
T14726 |
T14718 |
punct |
),4Q |
R4480 |
T14727 |
T14691 |
punct |
.,showed |
R4481 |
T14729 |
T14730 |
nsubj |
Initiation,was |
R4482 |
T14731 |
T14729 |
prep |
of,Initiation |
R4483 |
T14732 |
T14733 |
amod |
ectopic,buds |
R4484 |
T14733 |
T14731 |
pobj |
buds,of |
R4485 |
T14734 |
T14733 |
amod |
tooth,buds |
R4486 |
T14735 |
T14729 |
prep |
in,Initiation |
R4487 |
T14736 |
T14737 |
det |
the,mice |
R4488 |
T14737 |
T14735 |
pobj |
mice,in |
R4489 |
T14738 |
T14737 |
amod |
mutant,mice |
R4490 |
T14739 |
T14730 |
acomp |
evident,was |
R4491 |
T14740 |
T14730 |
prep |
at,was |
R4492 |
T14741 |
T14740 |
pobj |
E15.5,at |
R4493 |
T14742 |
T14730 |
prep |
by,was |
R4494 |
T14743 |
T14744 |
amod |
extra,dots |
R4495 |
T14744 |
T14742 |
pobj |
dots,by |
R4496 |
T14745 |
T14744 |
prep |
of,dots |
R4497 |
T14746 |
T14747 |
compound |
Shh,expression |
R4498 |
T14747 |
T14745 |
pobj |
expression,of |
R4499 |
T14748 |
T14744 |
amod |
adjacent,dots |
R4500 |
T14749 |
T14748 |
prep |
to,adjacent |
R4501 |
T14750 |
T14751 |
det |
the,teeth |
R4502 |
T14751 |
T14749 |
pobj |
teeth,to |
R4503 |
T14752 |
T14751 |
amod |
primary,teeth |
R4504 |
T14753 |
T14754 |
punct |
(,shown |
R4505 |
T14754 |
T14730 |
parataxis |
shown,was |
R4506 |
T14755 |
T14754 |
nsubj |
data,shown |
R4507 |
T14756 |
T14754 |
neg |
not,shown |
R4508 |
T14757 |
T14754 |
punct |
),shown |
R4509 |
T14758 |
T14730 |
punct |
.,was |
R4510 |
T14760 |
T14761 |
nsubj |
Loss,leads |
R4511 |
T14762 |
T14760 |
prep |
of,Loss |
R4512 |
T14763 |
T14762 |
pobj |
Apc,of |
R4513 |
T14764 |
T14761 |
advmod |
also,leads |
R4514 |
T14765 |
T14761 |
prep |
to,leads |
R4515 |
T14766 |
T14765 |
pobj |
hyperplasia,to |
R4516 |
T14767 |
T14766 |
prep |
in,hyperplasia |
R4517 |
T14768 |
T14769 |
amod |
squamous,epithelia |
R4518 |
T14769 |
T14767 |
pobj |
epithelia,in |
R4519 |
T14770 |
T14769 |
prep |
of,epithelia |
R4520 |
T14771 |
T14772 |
nmod |
cornea,glands |
R4521 |
T14772 |
T14770 |
pobj |
glands,of |
R4522 |
T14773 |
T14771 |
punct |
", ",cornea |
R4523 |
T14774 |
T14771 |
conj |
oral,cornea |
R4524 |
T14775 |
T14774 |
punct |
", ",oral |
R4525 |
T14776 |
T14774 |
conj |
salivary,oral |
R4526 |
T14777 |
T14776 |
punct |
", ",salivary |
R4527 |
T14778 |
T14776 |
cc |
and,salivary |
R4528 |
T14779 |
T14776 |
conj |
Hardarian,salivary |
R4529 |
T14780 |
T14781 |
punct |
(,data |
R4530 |
T14781 |
T14761 |
meta |
data,leads |
R4531 |
T14782 |
T14781 |
amod |
unpublished,data |
R4532 |
T14783 |
T14781 |
punct |
),data |
R4533 |
T14784 |
T14761 |
punct |
.,leads |
R4534 |
T14786 |
T14787 |
amod |
Squamous,metaplasia |
R4535 |
T14787 |
T14788 |
nsubjpass |
metaplasia,observed |
R4536 |
T14789 |
T14787 |
prep |
to,metaplasia |
R4537 |
T14790 |
T14791 |
compound |
hair,follicle |
R4538 |
T14791 |
T14792 |
npadvmod |
follicle,like |
R4539 |
T14792 |
T14794 |
amod |
like,structures |
R4540 |
T14793 |
T14792 |
punct |
–,like |
R4541 |
T14794 |
T14789 |
pobj |
structures,to |
R4542 |
T14795 |
T14787 |
punct |
", ",metaplasia |
R4543 |
T14796 |
T14797 |
amod |
ectopic,morphogenesis |
R4544 |
T14797 |
T14787 |
appos |
morphogenesis,metaplasia |
R4545 |
T14798 |
T14799 |
compound |
hair,follicle |
R4546 |
T14799 |
T14797 |
compound |
follicle,morphogenesis |
R4547 |
T14800 |
T14788 |
auxpass |
was,observed |
R4548 |
T14801 |
T14788 |
advmod |
also,observed |
R4549 |
T14802 |
T14788 |
prep |
in,observed |
R4550 |
T14803 |
T14804 |
det |
these,epithelia |
R4551 |
T14804 |
T14802 |
pobj |
epithelia,in |
R4552 |
T14805 |
T14788 |
punct |
.,observed |