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PMC:1420314 / 16445-17297 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T11135 0-6 NN denotes ADAM11
T11137 6-7 HYPH denotes -
T11136 7-16 JJ denotes deficient
T11138 17-21 NNS denotes mice
T11139 22-30 VBD denotes remained
T11140 31-36 JJ denotes alive
T11141 37-40 IN denotes for
T11142 41-45 JJR denotes more
T11144 46-50 IN denotes than
T11143 51-54 CD denotes one
T11145 55-59 NN denotes year
T11146 60-67 IN denotes without
T11147 68-74 NN denotes ataxia
T11148 75-77 CC denotes or
T11149 78-84 NN denotes tremor
T11150 84-86 , denotes ,
T11151 86-89 CC denotes but
T11152 90-96 VBD denotes showed
T11153 97-98 DT denotes a
T11154 99-106 NN denotes deficit
T11155 107-109 IN denotes in
T11156 110-117 JJ denotes spatial
T11157 118-126 NN denotes learning
T11158 127-130 CC denotes and
T11159 131-136 NN denotes motor
T11160 137-148 NN denotes dysfunction
T11161 148-149 . denotes .
T11162 149-308 sentence denotes On the other hand, mice lacking the Adam22 gene showed severe ataxia, exhibited marked hypomyelination of the peripheral nerves, and died before weaning [22].
T11163 150-152 IN denotes On
T11165 153-156 DT denotes the
T11167 157-162 JJ denotes other
T11166 163-167 NN denotes hand
T11168 167-169 , denotes ,
T11169 169-173 NNS denotes mice
T11170 174-181 VBG denotes lacking
T11171 182-185 DT denotes the
T11173 186-192 NN denotes Adam22
T11172 193-197 NN denotes gene
T11164 198-204 VBD denotes showed
T11174 205-211 JJ denotes severe
T11175 212-218 NN denotes ataxia
T11176 218-220 , denotes ,
T11177 220-229 VBD denotes exhibited
T11178 230-236 JJ denotes marked
T11179 237-252 NN denotes hypomyelination
T11180 253-255 IN denotes of
T11181 256-259 DT denotes the
T11183 260-270 JJ denotes peripheral
T11182 271-277 NNS denotes nerves
T11184 277-279 , denotes ,
T11185 279-282 CC denotes and
T11186 283-287 VBD denotes died
T11187 288-294 IN denotes before
T11188 295-302 NN denotes weaning
T11189 303-304 -LRB- denotes [
T11190 304-306 CD denotes 22
T11191 306-307 -RRB- denotes ]
T11192 307-308 . denotes .
T11193 308-399 sentence denotes Mice lacking the Adam23 gene showed severe ataxia and tremor and died before weaning [23].
T11194 309-313 NNS denotes Mice
T11196 314-321 VBG denotes lacking
T11197 322-325 DT denotes the
T11199 326-332 NN denotes Adam23
T11198 333-337 NN denotes gene
T11195 338-344 VBD denotes showed
T11200 345-351 JJ denotes severe
T11201 352-358 NN denotes ataxia
T11202 359-362 CC denotes and
T11203 363-369 NN denotes tremor
T11204 370-373 CC denotes and
T11205 374-378 VBD denotes died
T11206 379-385 IN denotes before
T11207 386-393 NN denotes weaning
T11208 394-395 -LRB- denotes [
T11209 395-397 CD denotes 23
T11210 397-398 -RRB- denotes ]
T11211 398-399 . denotes .
T11212 399-510 sentence denotes These findings suggest that ADAM11, ADAM22 and ADAM23 have separate and important roles in the nervous system.
T11213 400-405 DT denotes These
T11214 406-414 NNS denotes findings
T11215 415-422 VBP denotes suggest
T11216 423-427 IN denotes that
T11218 428-434 NN denotes ADAM11
T11219 434-436 , denotes ,
T11220 436-442 NN denotes ADAM22
T11221 443-446 CC denotes and
T11222 447-453 NN denotes ADAM23
T11217 454-458 VBP denotes have
T11223 459-467 JJ denotes separate
T11225 468-471 CC denotes and
T11226 472-481 JJ denotes important
T11224 482-487 NNS denotes roles
T11227 488-490 IN denotes in
T11228 491-494 DT denotes the
T11230 495-502 JJ denotes nervous
T11229 503-509 NN denotes system
T11231 509-510 . denotes .
T11232 510-678 sentence denotes A genome database search revealed orthologs of ADAM11, ADAM22 and ADAM23 genes to exist in vertebrates such as mammals, fish, and amphibians, but not in invertebrates.
T11233 511-512 DT denotes A
T11235 513-519 NN denotes genome
T11236 520-528 NN denotes database
T11234 529-535 NN denotes search
T11237 536-544 VBD denotes revealed
T11238 545-554 NNS denotes orthologs
T11240 555-557 IN denotes of
T11241 558-564 NN denotes ADAM11
T11243 564-566 , denotes ,
T11244 566-572 NN denotes ADAM22
T11245 573-576 CC denotes and
T11246 577-583 NN denotes ADAM23
T11242 584-589 NNS denotes genes
T11247 590-592 TO denotes to
T11239 593-598 VB denotes exist
T11248 599-601 IN denotes in
T11249 602-613 NNS denotes vertebrates
T11250 614-618 JJ denotes such
T11251 619-621 IN denotes as
T11252 622-629 NNS denotes mammals
T11253 629-631 , denotes ,
T11254 631-635 NNS denotes fish
T11255 635-637 , denotes ,
T11256 637-640 CC denotes and
T11257 641-651 NNS denotes amphibians
T11258 651-653 , denotes ,
T11259 653-656 CC denotes but
T11260 657-660 RB denotes not
T11261 661-663 IN denotes in
T11262 664-677 NNS denotes invertebrates
T11263 677-678 . denotes .
T11264 678-852 sentence denotes Although the precise molecular functions of these ADAMs are still unclear, further investigations will provide clues to understanding the nervous system of higher organisms.
T11265 679-687 IN denotes Although
T11267 688-691 DT denotes the
T11269 692-699 JJ denotes precise
T11270 700-709 JJ denotes molecular
T11268 710-719 NNS denotes functions
T11271 720-722 IN denotes of
T11272 723-728 DT denotes these
T11273 729-734 NNS denotes ADAMs
T11266 735-738 VBP denotes are
T11275 739-744 RB denotes still
T11276 745-752 JJ denotes unclear
T11277 752-754 , denotes ,
T11278 754-761 JJ denotes further
T11279 762-776 NNS denotes investigations
T11280 777-781 MD denotes will
T11274 782-789 VB denotes provide
T11281 790-795 NNS denotes clues
T11282 796-798 IN denotes to
T11283 799-812 VBG denotes understanding
T11284 813-816 DT denotes the
T11286 817-824 JJ denotes nervous
T11285 825-831 NN denotes system
T11287 832-834 IN denotes of
T11288 835-841 JJR denotes higher
T11289 842-851 NNS denotes organisms
T11290 851-852 . denotes .
R3235 T11165 T11166 det the,hand
R3237 T11166 T11163 pobj hand,On
R3238 T11167 T11166 amod other,hand
R3240 T11168 T11164 punct ", ",showed
R3241 T11169 T11164 nsubj mice,showed
R3243 T11170 T11169 acl lacking,mice
R3244 T11171 T11172 det the,gene
R3245 T11172 T11170 dobj gene,lacking
R3247 T11173 T11172 compound Adam22,gene
R3248 T11174 T11175 amod severe,ataxia
R3249 T11175 T11164 dobj ataxia,showed
R3251 T11176 T11164 punct ", ",showed
R3252 T11177 T11164 conj exhibited,showed
R3254 T11178 T11179 amod marked,hypomyelination
R3255 T11179 T11177 dobj hypomyelination,exhibited
R3256 T11180 T11179 prep of,hypomyelination
R3258 T11181 T11182 det the,nerves
R3259 T11182 T11180 pobj nerves,of
R3260 T11183 T11182 amod peripheral,nerves
R3262 T11184 T11177 punct ", ",exhibited
R3263 T11185 T11177 cc and,exhibited
R3264 T11186 T11177 conj died,exhibited
R3266 T11187 T11186 prep before,died
R3267 T11188 T11187 pobj weaning,before
R3268 T11189 T11190 punct [,22
R3270 T11190 T11186 parataxis 22,died
R3271 T11191 T11190 punct ],22
R3272 T11192 T11164 punct .,showed
R3274 T11194 T11195 nsubj Mice,showed
R3276 T11196 T11194 acl lacking,Mice
R3277 T11197 T11198 det the,gene
R3279 T11198 T11196 dobj gene,lacking
R3280 T11199 T11198 compound Adam23,gene
R3281 T11200 T11201 amod severe,ataxia
R3283 T11201 T11195 dobj ataxia,showed
R3285 T11202 T11201 cc and,ataxia
R3287 T11203 T11201 conj tremor,ataxia
R3288 T11204 T11195 cc and,showed
R3289 T11205 T11195 conj died,showed
R3291 T11206 T11205 prep before,died
R3292 T11207 T11206 pobj weaning,before
R3293 T11208 T11209 punct [,23
R3295 T11209 T11205 parataxis 23,died
R3296 T11210 T11209 punct ],23
R3297 T11211 T11195 punct .,showed
R3299 T11213 T11214 det These,findings
R3301 T11214 T11215 nsubj findings,suggest
R3302 T11216 T11217 mark that,have
R3304 T11217 T11215 ccomp have,suggest
R3305 T11218 T11217 nsubj ADAM11,have
R3306 T11219 T11218 punct ", ",ADAM11
R3308 T11220 T11218 conj ADAM22,ADAM11
R3309 T11221 T11220 cc and,ADAM22
R3310 T11222 T11220 conj ADAM23,ADAM22
R3312 T11223 T11224 amod separate,roles
R3313 T11224 T11217 dobj roles,have
R3314 T11225 T11223 cc and,separate
R3315 T11226 T11223 conj important,separate
R3317 T11227 T11224 prep in,roles
R3318 T11228 T11229 det the,system
R3319 T11229 T11227 pobj system,in
R3321 T11230 T11229 amod nervous,system
R3322 T11231 T11215 punct .,suggest
R3324 T11233 T11234 det A,search
R3325 T11234 T11237 nsubj search,revealed
R3327 T11235 T11234 compound genome,search
R3328 T11236 T11234 compound database,search
R3330 T11238 T11239 nsubj orthologs,exist
R3332 T11239 T11237 ccomp exist,revealed
R3334 T11240 T11238 prep of,orthologs
R3335 T11241 T11242 nmod ADAM11,genes
R3337 T11242 T11240 pobj genes,of
R3338 T11243 T11241 punct ", ",ADAM11
R3339 T11244 T11241 conj ADAM22,ADAM11
R3340 T11245 T11244 cc and,ADAM22
R3341 T11246 T11244 conj ADAM23,ADAM22
R3342 T11247 T11239 aux to,exist
R3344 T11248 T11239 prep in,exist
R3345 T11249 T11248 pobj vertebrates,in
R3347 T11250 T11251 amod such,as
R3348 T11251 T11249 prep as,vertebrates
R3350 T11252 T11251 pobj mammals,as
R3351 T11253 T11252 punct ", ",mammals
R3352 T11254 T11252 conj fish,mammals
R3354 T11255 T11254 punct ", ",fish
R3355 T11256 T11254 cc and,fish
R3356 T11257 T11254 conj amphibians,fish
R3358 T11258 T11248 punct ", ",in
R3359 T11259 T11248 cc but,in
R3360 T11260 T11259 neg not,but
R3362 T11261 T11248 conj in,in
R3363 T11262 T11261 pobj invertebrates,in
R3364 T11263 T11237 punct .,revealed
R3366 T11265 T11266 mark Although,are
R3368 T11266 T11274 advcl are,provide
R3369 T11267 T11268 det the,functions
R3370 T11268 T11266 nsubj functions,are
R3372 T11269 T11268 amod precise,functions
R3373 T11270 T11268 amod molecular,functions
R3375 T11271 T11268 prep of,functions
R3377 T11272 T11273 det these,ADAMs
R3378 T11273 T11271 pobj ADAMs,of
R3380 T11275 T11266 advmod still,are
R3381 T11276 T11266 acomp unclear,are
R3383 T11277 T11274 punct ", ",provide
R3384 T11278 T11279 amod further,investigations
R3385 T11279 T11274 nsubj investigations,provide
R3386 T11135 T11136 npadvmod ADAM11,deficient
R3387 T11280 T11274 aux will,provide
R3388 T11281 T11274 dobj clues,provide
R3389 T11282 T11281 prep to,clues
R3390 T11283 T11282 pcomp understanding,to
R3391 T11284 T11285 det the,system
R3392 T11285 T11283 dobj system,understanding
R3393 T11286 T11285 amod nervous,system
R3394 T11136 T11138 amod deficient,mice
R3395 T11287 T11285 prep of,system
R3396 T11288 T11289 amod higher,organisms
R3397 T11289 T11287 pobj organisms,of
R3398 T11137 T11136 punct -,deficient
R3399 T11290 T11274 punct .,provide
R3400 T11138 T11139 nsubj mice,remained
R3401 T11140 T11139 acomp alive,remained
R3402 T11141 T11139 prep for,remained
R3403 T11142 T11143 amod more,one
R3404 T11143 T11145 nummod one,year
R3405 T11144 T11143 quantmod than,one
R3406 T11145 T11141 pobj year,for
R3407 T11146 T11139 prep without,remained
R3408 T11147 T11146 pobj ataxia,without
R3409 T11148 T11147 cc or,ataxia
R3410 T11149 T11147 conj tremor,ataxia
R3411 T11150 T11139 punct ", ",remained
R3412 T11151 T11139 cc but,remained
R3413 T11152 T11139 conj showed,remained
R3414 T11153 T11154 det a,deficit
R3415 T11154 T11152 dobj deficit,showed
R3416 T11155 T11154 prep in,deficit
R3417 T11156 T11157 amod spatial,learning
R3418 T11157 T11155 pobj learning,in
R3419 T11158 T11157 cc and,learning
R3420 T11159 T11160 compound motor,dysfunction
R3421 T11160 T11157 conj dysfunction,learning
R3422 T11161 T11139 punct .,remained
R3423 T11163 T11164 prep On,showed