Id |
Subject |
Object |
Predicate |
Lexical cue |
T10785 |
0-5 |
DT |
denotes |
These |
T10786 |
6-13 |
NNS |
denotes |
results |
T10787 |
14-21 |
VBP |
denotes |
suggest |
T10788 |
22-26 |
IN |
denotes |
that |
T10790 |
27-34 |
JJ |
denotes |
limited |
T10792 |
35-40 |
NN |
denotes |
brain |
T10791 |
41-46 |
NNS |
denotes |
sites |
T10793 |
46-48 |
, |
denotes |
, |
T10794 |
48-54 |
RB |
denotes |
mainly |
T10796 |
55-58 |
DT |
denotes |
the |
T10795 |
59-70 |
NN |
denotes |
hippocampus |
T10797 |
71-74 |
CC |
denotes |
and |
T10798 |
75-85 |
NN |
denotes |
cerebellum |
T10799 |
85-87 |
, |
denotes |
, |
T10800 |
87-92 |
MD |
denotes |
might |
T10789 |
93-103 |
VB |
denotes |
contribute |
T10801 |
104-106 |
IN |
denotes |
to |
T10802 |
107-110 |
DT |
denotes |
the |
T10804 |
111-119 |
JJ |
denotes |
dominant |
T10803 |
120-129 |
NN |
denotes |
phenotype |
T10805 |
129-131 |
, |
denotes |
, |
T10806 |
131-138 |
JJ |
denotes |
spatial |
T10807 |
139-147 |
NN |
denotes |
learning |
T10808 |
148-158 |
NN |
denotes |
impairment |
T10809 |
159-162 |
CC |
denotes |
and |
T10810 |
163-168 |
NN |
denotes |
motor |
T10811 |
169-184 |
NN |
denotes |
discoordination |
T10812 |
185-187 |
IN |
denotes |
in |
T10813 |
188-194 |
NN |
denotes |
ADAM11 |
T10815 |
194-195 |
HYPH |
denotes |
- |
T10814 |
195-204 |
JJ |
denotes |
deficient |
T10816 |
205-209 |
NNS |
denotes |
mice |
T10817 |
209-210 |
. |
denotes |
. |
T10818 |
210-422 |
sentence |
denotes |
In situ hybridisation analysis has detected Adam11 gene expression in the pyramidal cells of CA1–CA3 fields and granule cells of the dentate gyrus in the hippocampus and in granular cells in the cerebellum [25]. |
T10819 |
211-213 |
FW |
denotes |
In |
T10820 |
214-218 |
FW |
denotes |
situ |
T10821 |
219-232 |
NN |
denotes |
hybridisation |
T10822 |
233-241 |
NN |
denotes |
analysis |
T10824 |
242-245 |
VBZ |
denotes |
has |
T10823 |
246-254 |
VBN |
denotes |
detected |
T10825 |
255-261 |
NN |
denotes |
Adam11 |
T10826 |
262-266 |
NN |
denotes |
gene |
T10827 |
267-277 |
NN |
denotes |
expression |
T10828 |
278-280 |
IN |
denotes |
in |
T10829 |
281-284 |
DT |
denotes |
the |
T10831 |
285-294 |
JJ |
denotes |
pyramidal |
T10830 |
295-300 |
NNS |
denotes |
cells |
T10832 |
301-303 |
IN |
denotes |
of |
T10833 |
304-307 |
NN |
denotes |
CA1 |
T10835 |
307-308 |
SYM |
denotes |
– |
T10836 |
308-311 |
NN |
denotes |
CA3 |
T10834 |
312-318 |
NNS |
denotes |
fields |
T10837 |
319-322 |
CC |
denotes |
and |
T10838 |
323-330 |
NN |
denotes |
granule |
T10839 |
331-336 |
NNS |
denotes |
cells |
T10840 |
337-339 |
IN |
denotes |
of |
T10841 |
340-343 |
DT |
denotes |
the |
T10843 |
344-351 |
NN |
denotes |
dentate |
T10842 |
352-357 |
NN |
denotes |
gyrus |
T10844 |
358-360 |
IN |
denotes |
in |
T10845 |
361-364 |
DT |
denotes |
the |
T10846 |
365-376 |
NN |
denotes |
hippocampus |
T10847 |
377-380 |
CC |
denotes |
and |
T10848 |
381-383 |
IN |
denotes |
in |
T10849 |
384-392 |
JJ |
denotes |
granular |
T10850 |
393-398 |
NNS |
denotes |
cells |
T10851 |
399-401 |
IN |
denotes |
in |
T10852 |
402-405 |
DT |
denotes |
the |
T10853 |
406-416 |
NN |
denotes |
cerebellum |
T10854 |
417-418 |
-LRB- |
denotes |
[ |
T10855 |
418-420 |
CD |
denotes |
25 |
T10856 |
420-421 |
-RRB- |
denotes |
] |
T10857 |
421-422 |
. |
denotes |
. |
T10858 |
422-728 |
sentence |
denotes |
It is unlikely that morphological changes during development led to impairment of spatial learning and motor coordination, and morphological alterations in the cytoarchitecture of the hippocampus and cerebellum were not observed in ADAM11-deficient mice after histological investigation using HE staining. |
T10859 |
423-425 |
PRP |
denotes |
It |
T10860 |
426-428 |
VBZ |
denotes |
is |
T10862 |
429-437 |
JJ |
denotes |
unlikely |
T10863 |
438-442 |
IN |
denotes |
that |
T10865 |
443-456 |
JJ |
denotes |
morphological |
T10866 |
457-464 |
NNS |
denotes |
changes |
T10867 |
465-471 |
IN |
denotes |
during |
T10868 |
472-483 |
NN |
denotes |
development |
T10864 |
484-487 |
VBD |
denotes |
led |
T10869 |
488-490 |
IN |
denotes |
to |
T10870 |
491-501 |
NN |
denotes |
impairment |
T10871 |
502-504 |
IN |
denotes |
of |
T10872 |
505-512 |
JJ |
denotes |
spatial |
T10873 |
513-521 |
NN |
denotes |
learning |
T10874 |
522-525 |
CC |
denotes |
and |
T10875 |
526-531 |
NN |
denotes |
motor |
T10876 |
532-544 |
NN |
denotes |
coordination |
T10877 |
544-546 |
, |
denotes |
, |
T10878 |
546-549 |
CC |
denotes |
and |
T10879 |
550-563 |
JJ |
denotes |
morphological |
T10880 |
564-575 |
NNS |
denotes |
alterations |
T10881 |
576-578 |
IN |
denotes |
in |
T10882 |
579-582 |
DT |
denotes |
the |
T10883 |
583-599 |
NN |
denotes |
cytoarchitecture |
T10884 |
600-602 |
IN |
denotes |
of |
T10885 |
603-606 |
DT |
denotes |
the |
T10886 |
607-618 |
NN |
denotes |
hippocampus |
T10887 |
619-622 |
CC |
denotes |
and |
T10888 |
623-633 |
NN |
denotes |
cerebellum |
T10889 |
634-638 |
VBD |
denotes |
were |
T10890 |
639-642 |
RB |
denotes |
not |
T10861 |
643-651 |
VBN |
denotes |
observed |
T10891 |
652-654 |
IN |
denotes |
in |
T10892 |
655-661 |
NN |
denotes |
ADAM11 |
T10894 |
661-662 |
HYPH |
denotes |
- |
T10893 |
662-671 |
JJ |
denotes |
deficient |
T10895 |
672-676 |
NNS |
denotes |
mice |
T10896 |
677-682 |
IN |
denotes |
after |
T10897 |
683-695 |
JJ |
denotes |
histological |
T10898 |
696-709 |
NN |
denotes |
investigation |
T10899 |
710-715 |
VBG |
denotes |
using |
T10900 |
716-718 |
NN |
denotes |
HE |
T10901 |
719-727 |
NN |
denotes |
staining |
T10902 |
727-728 |
. |
denotes |
. |
T10903 |
728-895 |
sentence |
denotes |
However, because it is thought that ADAM11 plays a role in neuron-neuron or neuron-glial cell interactions, a more precise morphological investigation will be needed. |
T10904 |
729-736 |
RB |
denotes |
However |
T10906 |
736-738 |
, |
denotes |
, |
T10907 |
738-745 |
IN |
denotes |
because |
T10909 |
746-748 |
PRP |
denotes |
it |
T10910 |
749-751 |
VBZ |
denotes |
is |
T10908 |
752-759 |
VBN |
denotes |
thought |
T10911 |
760-764 |
IN |
denotes |
that |
T10913 |
765-771 |
NN |
denotes |
ADAM11 |
T10912 |
772-777 |
VBZ |
denotes |
plays |
T10914 |
778-779 |
DT |
denotes |
a |
T10915 |
780-784 |
NN |
denotes |
role |
T10916 |
785-787 |
IN |
denotes |
in |
T10917 |
788-794 |
NN |
denotes |
neuron |
T10919 |
794-795 |
SYM |
denotes |
- |
T10918 |
795-801 |
NN |
denotes |
neuron |
T10921 |
802-804 |
CC |
denotes |
or |
T10922 |
805-811 |
NN |
denotes |
neuron |
T10924 |
811-812 |
SYM |
denotes |
- |
T10925 |
812-817 |
JJ |
denotes |
glial |
T10923 |
818-822 |
NN |
denotes |
cell |
T10920 |
823-835 |
NNS |
denotes |
interactions |
T10926 |
835-837 |
, |
denotes |
, |
T10927 |
837-838 |
DT |
denotes |
a |
T10929 |
839-843 |
RBR |
denotes |
more |
T10930 |
844-851 |
JJ |
denotes |
precise |
T10931 |
852-865 |
JJ |
denotes |
morphological |
T10928 |
866-879 |
NN |
denotes |
investigation |
T10932 |
880-884 |
MD |
denotes |
will |
T10933 |
885-887 |
VB |
denotes |
be |
T10905 |
888-894 |
VBN |
denotes |
needed |
T10934 |
894-895 |
. |
denotes |
. |
T10935 |
895-1171 |
sentence |
denotes |
It has been reported that adhesion molecules, such as neural cell adhesion molecule (NCAM), are not only implicated in cell interactions during nervous system development, but are also recognised as important mediators of synaptic plasticity in the adult nervous system [35]. |
T10936 |
896-898 |
PRP |
denotes |
It |
T10938 |
899-902 |
VBZ |
denotes |
has |
T10939 |
903-907 |
VBN |
denotes |
been |
T10937 |
908-916 |
VBN |
denotes |
reported |
T10940 |
917-921 |
IN |
denotes |
that |
T10942 |
922-930 |
NN |
denotes |
adhesion |
T10943 |
931-940 |
NNS |
denotes |
molecules |
T10944 |
940-942 |
, |
denotes |
, |
T10945 |
942-946 |
JJ |
denotes |
such |
T10946 |
947-949 |
IN |
denotes |
as |
T10947 |
950-956 |
JJ |
denotes |
neural |
T10948 |
957-961 |
NN |
denotes |
cell |
T10950 |
962-970 |
NN |
denotes |
adhesion |
T10949 |
971-979 |
NN |
denotes |
molecule |
T10951 |
980-981 |
-LRB- |
denotes |
( |
T10952 |
981-985 |
NN |
denotes |
NCAM |
T10953 |
985-986 |
-RRB- |
denotes |
) |
T10954 |
986-988 |
, |
denotes |
, |
T10955 |
988-991 |
VBP |
denotes |
are |
T10956 |
992-995 |
RB |
denotes |
not |
T10957 |
996-1000 |
RB |
denotes |
only |
T10941 |
1001-1011 |
VBN |
denotes |
implicated |
T10958 |
1012-1014 |
IN |
denotes |
in |
T10959 |
1015-1019 |
NN |
denotes |
cell |
T10960 |
1020-1032 |
NNS |
denotes |
interactions |
T10961 |
1033-1039 |
IN |
denotes |
during |
T10962 |
1040-1047 |
JJ |
denotes |
nervous |
T10963 |
1048-1054 |
NN |
denotes |
system |
T10964 |
1055-1066 |
NN |
denotes |
development |
T10965 |
1066-1068 |
, |
denotes |
, |
T10966 |
1068-1071 |
CC |
denotes |
but |
T10967 |
1072-1075 |
VBP |
denotes |
are |
T10969 |
1076-1080 |
RB |
denotes |
also |
T10968 |
1081-1091 |
VBN |
denotes |
recognised |
T10970 |
1092-1094 |
IN |
denotes |
as |
T10971 |
1095-1104 |
JJ |
denotes |
important |
T10972 |
1105-1114 |
NNS |
denotes |
mediators |
T10973 |
1115-1117 |
IN |
denotes |
of |
T10974 |
1118-1126 |
JJ |
denotes |
synaptic |
T10975 |
1127-1137 |
NN |
denotes |
plasticity |
T10976 |
1138-1140 |
IN |
denotes |
in |
T10977 |
1141-1144 |
DT |
denotes |
the |
T10979 |
1145-1150 |
JJ |
denotes |
adult |
T10980 |
1151-1158 |
JJ |
denotes |
nervous |
T10978 |
1159-1165 |
NN |
denotes |
system |
T10981 |
1166-1167 |
-LRB- |
denotes |
[ |
T10982 |
1167-1169 |
CD |
denotes |
35 |
T10983 |
1169-1170 |
-RRB- |
denotes |
] |
T10984 |
1170-1171 |
. |
denotes |
. |
T10985 |
1171-1444 |
sentence |
denotes |
Changes in neuron excitability in the hippocampus, such as decreases in the post-burst after hyperpolarization (AHP), have been thought to affect long-term potentiation (LTP) [36], an experimental model of the synaptic changes thought to underlie learning and memory [37]. |
T10986 |
1172-1179 |
NNS |
denotes |
Changes |
T10988 |
1180-1182 |
IN |
denotes |
in |
T10989 |
1183-1189 |
NN |
denotes |
neuron |
T10990 |
1190-1202 |
NN |
denotes |
excitability |
T10991 |
1203-1205 |
IN |
denotes |
in |
T10992 |
1206-1209 |
DT |
denotes |
the |
T10993 |
1210-1221 |
NN |
denotes |
hippocampus |
T10994 |
1221-1223 |
, |
denotes |
, |
T10995 |
1223-1227 |
JJ |
denotes |
such |
T10996 |
1228-1230 |
IN |
denotes |
as |
T10997 |
1231-1240 |
NNS |
denotes |
decreases |
T10998 |
1241-1243 |
IN |
denotes |
in |
T10999 |
1244-1247 |
DT |
denotes |
the |
T11000 |
1248-1258 |
JJ |
denotes |
post-burst |
T11001 |
1259-1264 |
IN |
denotes |
after |
T11002 |
1265-1282 |
NN |
denotes |
hyperpolarization |
T11003 |
1283-1284 |
-LRB- |
denotes |
( |
T11004 |
1284-1287 |
NN |
denotes |
AHP |
T11005 |
1287-1288 |
-RRB- |
denotes |
) |
T11006 |
1288-1290 |
, |
denotes |
, |
T11007 |
1290-1294 |
VBP |
denotes |
have |
T11008 |
1295-1299 |
VBN |
denotes |
been |
T10987 |
1300-1307 |
VBN |
denotes |
thought |
T11009 |
1308-1310 |
TO |
denotes |
to |
T11010 |
1311-1317 |
VB |
denotes |
affect |
T11011 |
1318-1322 |
JJ |
denotes |
long |
T11013 |
1322-1323 |
HYPH |
denotes |
- |
T11012 |
1323-1327 |
NN |
denotes |
term |
T11014 |
1328-1340 |
NN |
denotes |
potentiation |
T11015 |
1341-1342 |
-LRB- |
denotes |
( |
T11016 |
1342-1345 |
NN |
denotes |
LTP |
T11017 |
1345-1346 |
-RRB- |
denotes |
) |
T11018 |
1347-1348 |
-LRB- |
denotes |
[ |
T11019 |
1348-1350 |
CD |
denotes |
36 |
T11020 |
1350-1351 |
-RRB- |
denotes |
] |
T11021 |
1351-1353 |
, |
denotes |
, |
T11022 |
1353-1355 |
DT |
denotes |
an |
T11024 |
1356-1368 |
JJ |
denotes |
experimental |
T11023 |
1369-1374 |
NN |
denotes |
model |
T11025 |
1375-1377 |
IN |
denotes |
of |
T11026 |
1378-1381 |
DT |
denotes |
the |
T11028 |
1382-1390 |
JJ |
denotes |
synaptic |
T11027 |
1391-1398 |
NNS |
denotes |
changes |
T11029 |
1399-1406 |
VBN |
denotes |
thought |
T11030 |
1407-1409 |
TO |
denotes |
to |
T11031 |
1410-1418 |
VB |
denotes |
underlie |
T11032 |
1419-1427 |
NN |
denotes |
learning |
T11033 |
1428-1431 |
CC |
denotes |
and |
T11034 |
1432-1438 |
NN |
denotes |
memory |
T11035 |
1439-1440 |
-LRB- |
denotes |
[ |
T11036 |
1440-1442 |
CD |
denotes |
37 |
T11037 |
1442-1443 |
-RRB- |
denotes |
] |
T11038 |
1443-1444 |
. |
denotes |
. |
T11039 |
1444-1683 |
sentence |
denotes |
It has also been reported that mice lacking NMDA receptor for both NR2A and NR2C subunits showed motor dysfunction and complete loss of both spontaneous and evoked excitatory postsynaptic currents (EPSCs) in cerebellar granule cells [38]. |
T11040 |
1445-1447 |
PRP |
denotes |
It |
T11042 |
1448-1451 |
VBZ |
denotes |
has |
T11043 |
1452-1456 |
RB |
denotes |
also |
T11044 |
1457-1461 |
VBN |
denotes |
been |
T11041 |
1462-1470 |
VBN |
denotes |
reported |
T11045 |
1471-1475 |
IN |
denotes |
that |
T11047 |
1476-1480 |
NNS |
denotes |
mice |
T11048 |
1481-1488 |
VBG |
denotes |
lacking |
T11049 |
1489-1493 |
NN |
denotes |
NMDA |
T11050 |
1494-1502 |
NN |
denotes |
receptor |
T11051 |
1503-1506 |
IN |
denotes |
for |
T11052 |
1507-1511 |
CC |
denotes |
both |
T11054 |
1512-1516 |
NN |
denotes |
NR2A |
T11055 |
1517-1520 |
CC |
denotes |
and |
T11056 |
1521-1525 |
NN |
denotes |
NR2C |
T11053 |
1526-1534 |
NNS |
denotes |
subunits |
T11046 |
1535-1541 |
VBD |
denotes |
showed |
T11057 |
1542-1547 |
NN |
denotes |
motor |
T11058 |
1548-1559 |
NN |
denotes |
dysfunction |
T11059 |
1560-1563 |
CC |
denotes |
and |
T11060 |
1564-1572 |
JJ |
denotes |
complete |
T11061 |
1573-1577 |
NN |
denotes |
loss |
T11062 |
1578-1580 |
IN |
denotes |
of |
T11063 |
1581-1585 |
CC |
denotes |
both |
T11064 |
1586-1597 |
JJ |
denotes |
spontaneous |
T11066 |
1598-1601 |
CC |
denotes |
and |
T11067 |
1602-1608 |
VBN |
denotes |
evoked |
T11068 |
1609-1619 |
JJ |
denotes |
excitatory |
T11069 |
1620-1632 |
JJ |
denotes |
postsynaptic |
T11065 |
1633-1641 |
NNS |
denotes |
currents |
T11070 |
1642-1643 |
-LRB- |
denotes |
( |
T11071 |
1643-1648 |
NNS |
denotes |
EPSCs |
T11072 |
1648-1649 |
-RRB- |
denotes |
) |
T11073 |
1650-1652 |
IN |
denotes |
in |
T11074 |
1653-1663 |
JJ |
denotes |
cerebellar |
T11076 |
1664-1671 |
NN |
denotes |
granule |
T11075 |
1672-1677 |
NNS |
denotes |
cells |
T11077 |
1678-1679 |
-LRB- |
denotes |
[ |
T11078 |
1679-1681 |
CD |
denotes |
38 |
T11079 |
1681-1682 |
-RRB- |
denotes |
] |
T11080 |
1682-1683 |
. |
denotes |
. |
T11081 |
1683-1855 |
sentence |
denotes |
Therefore, electrophyological studies to enable analysis of synaptic transmission and plasticity in the hippocampus and cerebellum of ADAM11-deficient mice will be needed. |
T11082 |
1684-1693 |
RB |
denotes |
Therefore |
T11084 |
1693-1695 |
, |
denotes |
, |
T11085 |
1695-1713 |
JJ |
denotes |
electrophyological |
T11086 |
1714-1721 |
NNS |
denotes |
studies |
T11087 |
1722-1724 |
TO |
denotes |
to |
T11088 |
1725-1731 |
VB |
denotes |
enable |
T11089 |
1732-1740 |
NN |
denotes |
analysis |
T11090 |
1741-1743 |
IN |
denotes |
of |
T11091 |
1744-1752 |
JJ |
denotes |
synaptic |
T11092 |
1753-1765 |
NN |
denotes |
transmission |
T11093 |
1766-1769 |
CC |
denotes |
and |
T11094 |
1770-1780 |
NN |
denotes |
plasticity |
T11095 |
1781-1783 |
IN |
denotes |
in |
T11096 |
1784-1787 |
DT |
denotes |
the |
T11097 |
1788-1799 |
NN |
denotes |
hippocampus |
T11098 |
1800-1803 |
CC |
denotes |
and |
T11099 |
1804-1814 |
NN |
denotes |
cerebellum |
T11100 |
1815-1817 |
IN |
denotes |
of |
T11101 |
1818-1824 |
NN |
denotes |
ADAM11 |
T11103 |
1824-1825 |
HYPH |
denotes |
- |
T11102 |
1825-1834 |
JJ |
denotes |
deficient |
T11104 |
1835-1839 |
NNS |
denotes |
mice |
T11105 |
1840-1844 |
MD |
denotes |
will |
T11106 |
1845-1847 |
VB |
denotes |
be |
T11083 |
1848-1854 |
VBN |
denotes |
needed |
T11107 |
1854-1855 |
. |
denotes |
. |
T11108 |
1855-2021 |
sentence |
denotes |
These studies might clarify whether ADAM11 plays an important signalling or structural role at the synaptic level and whether it participates in synaptic regulation. |
T11109 |
1856-1861 |
DT |
denotes |
These |
T11110 |
1862-1869 |
NNS |
denotes |
studies |
T11112 |
1870-1875 |
MD |
denotes |
might |
T11111 |
1876-1883 |
VB |
denotes |
clarify |
T11113 |
1884-1891 |
IN |
denotes |
whether |
T11115 |
1892-1898 |
NN |
denotes |
ADAM11 |
T11114 |
1899-1904 |
VBZ |
denotes |
plays |
T11116 |
1905-1907 |
DT |
denotes |
an |
T11118 |
1908-1917 |
JJ |
denotes |
important |
T11119 |
1918-1928 |
NN |
denotes |
signalling |
T11120 |
1929-1931 |
CC |
denotes |
or |
T11121 |
1932-1942 |
JJ |
denotes |
structural |
T11117 |
1943-1947 |
NN |
denotes |
role |
T11122 |
1948-1950 |
IN |
denotes |
at |
T11123 |
1951-1954 |
DT |
denotes |
the |
T11125 |
1955-1963 |
JJ |
denotes |
synaptic |
T11124 |
1964-1969 |
NN |
denotes |
level |
T11126 |
1970-1973 |
CC |
denotes |
and |
T11127 |
1974-1981 |
IN |
denotes |
whether |
T11129 |
1982-1984 |
PRP |
denotes |
it |
T11128 |
1985-1997 |
VBZ |
denotes |
participates |
T11130 |
1998-2000 |
IN |
denotes |
in |
T11131 |
2001-2009 |
JJ |
denotes |
synaptic |
T11132 |
2010-2020 |
NN |
denotes |
regulation |
T11133 |
2020-2021 |
. |
denotes |
. |
R2874 |
T10785 |
T10786 |
det |
These,results |
R2876 |
T10786 |
T10787 |
nsubj |
results,suggest |
R2877 |
T10788 |
T10789 |
mark |
that,contribute |
R2879 |
T10789 |
T10787 |
ccomp |
contribute,suggest |
R2880 |
T10790 |
T10791 |
amod |
limited,sites |
R2882 |
T10791 |
T10789 |
nsubj |
sites,contribute |
R2883 |
T10792 |
T10791 |
compound |
brain,sites |
R2884 |
T10793 |
T10791 |
punct |
", ",sites |
R2886 |
T10794 |
T10795 |
advmod |
mainly,hippocampus |
R2887 |
T10795 |
T10791 |
appos |
hippocampus,sites |
R2888 |
T10796 |
T10795 |
det |
the,hippocampus |
R2890 |
T10797 |
T10795 |
cc |
and,hippocampus |
R2891 |
T10798 |
T10795 |
conj |
cerebellum,hippocampus |
R2892 |
T10799 |
T10789 |
punct |
", ",contribute |
R2894 |
T10800 |
T10789 |
aux |
might,contribute |
R2895 |
T10801 |
T10789 |
prep |
to,contribute |
R2896 |
T10802 |
T10803 |
det |
the,phenotype |
R2898 |
T10803 |
T10801 |
pobj |
phenotype,to |
R2899 |
T10804 |
T10803 |
amod |
dominant,phenotype |
R2900 |
T10805 |
T10803 |
punct |
", ",phenotype |
R2902 |
T10806 |
T10807 |
amod |
spatial,learning |
R2903 |
T10807 |
T10808 |
compound |
learning,impairment |
R2904 |
T10808 |
T10803 |
appos |
impairment,phenotype |
R2906 |
T10809 |
T10808 |
cc |
and,impairment |
R2907 |
T10810 |
T10811 |
compound |
motor,discoordination |
R2908 |
T10811 |
T10808 |
conj |
discoordination,impairment |
R2910 |
T10812 |
T10789 |
prep |
in,contribute |
R2911 |
T10813 |
T10814 |
npadvmod |
ADAM11,deficient |
R2915 |
T10814 |
T10816 |
amod |
deficient,mice |
R2917 |
T10815 |
T10814 |
punct |
-,deficient |
R2918 |
T10816 |
T10812 |
pobj |
mice,in |
R2919 |
T10817 |
T10787 |
punct |
.,suggest |
R2921 |
T10819 |
T10820 |
advmod |
In,situ |
R2922 |
T10820 |
T10821 |
amod |
situ,hybridisation |
R2923 |
T10821 |
T10822 |
compound |
hybridisation,analysis |
R2925 |
T10822 |
T10823 |
nsubj |
analysis,detected |
R2926 |
T10824 |
T10823 |
aux |
has,detected |
R2928 |
T10825 |
T10826 |
compound |
Adam11,gene |
R2929 |
T10826 |
T10827 |
compound |
gene,expression |
R2930 |
T10827 |
T10823 |
dobj |
expression,detected |
R2932 |
T10828 |
T10823 |
prep |
in,detected |
R2933 |
T10829 |
T10830 |
det |
the,cells |
R2935 |
T10830 |
T10828 |
pobj |
cells,in |
R2936 |
T10831 |
T10830 |
amod |
pyramidal,cells |
R2937 |
T10832 |
T10830 |
prep |
of,cells |
R2939 |
T10833 |
T10834 |
nmod |
CA1,fields |
R2940 |
T10834 |
T10832 |
pobj |
fields,of |
R2941 |
T10835 |
T10836 |
punct |
–,CA3 |
R2943 |
T10836 |
T10833 |
prep |
CA3,CA1 |
R2944 |
T10837 |
T10830 |
cc |
and,cells |
R2946 |
T10838 |
T10839 |
compound |
granule,cells |
R2947 |
T10839 |
T10830 |
conj |
cells,cells |
R2948 |
T10840 |
T10839 |
prep |
of,cells |
R2950 |
T10841 |
T10842 |
det |
the,gyrus |
R2951 |
T10842 |
T10840 |
pobj |
gyrus,of |
R2952 |
T10843 |
T10842 |
compound |
dentate,gyrus |
R2954 |
T10844 |
T10842 |
prep |
in,gyrus |
R2955 |
T10845 |
T10846 |
det |
the,hippocampus |
R2956 |
T10846 |
T10844 |
pobj |
hippocampus,in |
R2960 |
T10847 |
T10844 |
cc |
and,in |
R2961 |
T10848 |
T10844 |
conj |
in,in |
R2963 |
T10849 |
T10850 |
amod |
granular,cells |
R2964 |
T10850 |
T10848 |
pobj |
cells,in |
R2965 |
T10851 |
T10850 |
prep |
in,cells |
R2966 |
T10852 |
T10853 |
det |
the,cerebellum |
R2968 |
T10853 |
T10851 |
pobj |
cerebellum,in |
R2969 |
T10854 |
T10855 |
punct |
[,25 |
R2971 |
T10855 |
T10823 |
parataxis |
25,detected |
R2972 |
T10856 |
T10855 |
punct |
],25 |
R2973 |
T10857 |
T10823 |
punct |
.,detected |
R2974 |
T10859 |
T10860 |
nsubj |
It,is |
R2975 |
T10860 |
T10861 |
ccomp |
is,observed |
R2976 |
T10862 |
T10860 |
acomp |
unlikely,is |
R2978 |
T10863 |
T10864 |
mark |
that,led |
R2979 |
T10864 |
T10860 |
ccomp |
led,is |
R2980 |
T10865 |
T10866 |
amod |
morphological,changes |
R2982 |
T10866 |
T10864 |
nsubj |
changes,led |
R2983 |
T10867 |
T10866 |
prep |
during,changes |
R2984 |
T10868 |
T10867 |
pobj |
development,during |
R2986 |
T10869 |
T10864 |
prep |
to,led |
R2987 |
T10870 |
T10869 |
pobj |
impairment,to |
R2988 |
T10871 |
T10870 |
prep |
of,impairment |
R2990 |
T10872 |
T10873 |
amod |
spatial,learning |
R2991 |
T10873 |
T10871 |
pobj |
learning,of |
R2992 |
T10874 |
T10873 |
cc |
and,learning |
R2994 |
T10875 |
T10876 |
compound |
motor,coordination |
R2995 |
T10876 |
T10873 |
conj |
coordination,learning |
R2996 |
T10877 |
T10861 |
punct |
", ",observed |
R2998 |
T10878 |
T10861 |
cc |
and,observed |
R2999 |
T10879 |
T10880 |
amod |
morphological,alterations |
R3000 |
T10880 |
T10861 |
nsubjpass |
alterations,observed |
R3002 |
T10881 |
T10880 |
prep |
in,alterations |
R3003 |
T10882 |
T10883 |
det |
the,cytoarchitecture |
R3004 |
T10883 |
T10881 |
pobj |
cytoarchitecture,in |
R3006 |
T10884 |
T10883 |
prep |
of,cytoarchitecture |
R3007 |
T10885 |
T10886 |
det |
the,hippocampus |
R3008 |
T10886 |
T10884 |
pobj |
hippocampus,of |
R3010 |
T10887 |
T10886 |
cc |
and,hippocampus |
R3011 |
T10888 |
T10886 |
conj |
cerebellum,hippocampus |
R3012 |
T10889 |
T10861 |
auxpass |
were,observed |
R3014 |
T10890 |
T10861 |
neg |
not,observed |
R3015 |
T10891 |
T10861 |
prep |
in,observed |
R3016 |
T10892 |
T10893 |
npadvmod |
ADAM11,deficient |
R3018 |
T10893 |
T10895 |
amod |
deficient,mice |
R3019 |
T10894 |
T10893 |
punct |
-,deficient |
R3020 |
T10895 |
T10891 |
pobj |
mice,in |
R3022 |
T10896 |
T10861 |
prep |
after,observed |
R3023 |
T10897 |
T10898 |
amod |
histological,investigation |
R3024 |
T10898 |
T10896 |
pobj |
investigation,after |
R3026 |
T10899 |
T10898 |
acl |
using,investigation |
R3028 |
T10900 |
T10901 |
compound |
HE,staining |
R3029 |
T10901 |
T10899 |
dobj |
staining,using |
R3031 |
T10902 |
T10861 |
punct |
.,observed |
R3032 |
T10904 |
T10905 |
advmod |
However,needed |
R3034 |
T10906 |
T10905 |
punct |
", ",needed |
R3036 |
T10907 |
T10908 |
mark |
because,thought |
R3037 |
T10908 |
T10905 |
advcl |
thought,needed |
R3038 |
T10909 |
T10908 |
nsubjpass |
it,thought |
R3040 |
T10910 |
T10908 |
auxpass |
is,thought |
R3041 |
T10911 |
T10912 |
mark |
that,plays |
R3042 |
T10912 |
T10908 |
ccomp |
plays,thought |
R3044 |
T10913 |
T10912 |
nsubj |
ADAM11,plays |
R3045 |
T10914 |
T10915 |
det |
a,role |
R3047 |
T10915 |
T10912 |
dobj |
role,plays |
R3048 |
T10916 |
T10912 |
prep |
in,plays |
R3049 |
T10917 |
T10918 |
nmod |
neuron,neuron |
R3051 |
T10918 |
T10920 |
nmod |
neuron,interactions |
R3052 |
T10919 |
T10918 |
punct |
-,neuron |
R3053 |
T10920 |
T10916 |
pobj |
interactions,in |
R3054 |
T10921 |
T10918 |
cc |
or,neuron |
R3056 |
T10922 |
T10923 |
nmod |
neuron,cell |
R3057 |
T10923 |
T10918 |
conj |
cell,neuron |
R3058 |
T10924 |
T10923 |
punct |
-,cell |
R3060 |
T10925 |
T10923 |
amod |
glial,cell |
R3061 |
T10926 |
T10905 |
punct |
", ",needed |
R3062 |
T10927 |
T10928 |
det |
a,investigation |
R3064 |
T10928 |
T10905 |
nsubjpass |
investigation,needed |
R3065 |
T10929 |
T10930 |
advmod |
more,precise |
R3066 |
T10930 |
T10928 |
amod |
precise,investigation |
R3068 |
T10931 |
T10928 |
amod |
morphological,investigation |
R3069 |
T10932 |
T10905 |
aux |
will,needed |
R3070 |
T10933 |
T10905 |
auxpass |
be,needed |
R3072 |
T10934 |
T10905 |
punct |
.,needed |
R3073 |
T10936 |
T10937 |
nsubjpass |
It,reported |
R3075 |
T10938 |
T10937 |
aux |
has,reported |
R3076 |
T10939 |
T10937 |
auxpass |
been,reported |
R3077 |
T10940 |
T10941 |
mark |
that,implicated |
R3078 |
T10941 |
T10937 |
ccomp |
implicated,reported |
R3080 |
T10942 |
T10943 |
compound |
adhesion,molecules |
R3081 |
T10943 |
T10941 |
nsubjpass |
molecules,implicated |
R3082 |
T10944 |
T10943 |
punct |
", ",molecules |
R3084 |
T10945 |
T10946 |
amod |
such,as |
R3085 |
T10946 |
T10943 |
prep |
as,molecules |
R3086 |
T10947 |
T10948 |
amod |
neural,cell |
R3088 |
T10948 |
T10949 |
compound |
cell,molecule |
R3089 |
T10949 |
T10946 |
pobj |
molecule,as |
R3090 |
T10950 |
T10949 |
compound |
adhesion,molecule |
R3091 |
T10951 |
T10949 |
punct |
(,molecule |
R3092 |
T10952 |
T10949 |
appos |
NCAM,molecule |
R3095 |
T10953 |
T10941 |
punct |
),implicated |
R3097 |
T10954 |
T10941 |
punct |
", ",implicated |
R3098 |
T10955 |
T10941 |
auxpass |
are,implicated |
R3100 |
T10956 |
T10941 |
preconj |
not,implicated |
R3101 |
T10957 |
T10956 |
advmod |
only,not |
R3102 |
T10958 |
T10941 |
prep |
in,implicated |
R3104 |
T10959 |
T10960 |
compound |
cell,interactions |
R3105 |
T10960 |
T10958 |
pobj |
interactions,in |
R3106 |
T10961 |
T10941 |
prep |
during,implicated |
R3108 |
T10962 |
T10963 |
amod |
nervous,system |
R3109 |
T10963 |
T10964 |
compound |
system,development |
R3110 |
T10964 |
T10961 |
pobj |
development,during |
R3112 |
T10965 |
T10941 |
punct |
", ",implicated |
R3113 |
T10966 |
T10941 |
cc |
but,implicated |
R3114 |
T10967 |
T10968 |
auxpass |
are,recognised |
R3116 |
T10968 |
T10941 |
conj |
recognised,implicated |
R3117 |
T10969 |
T10968 |
advmod |
also,recognised |
R3119 |
T10970 |
T10968 |
prep |
as,recognised |
R3120 |
T10971 |
T10972 |
amod |
important,mediators |
R3121 |
T10972 |
T10970 |
pobj |
mediators,as |
R3123 |
T10973 |
T10972 |
prep |
of,mediators |
R3124 |
T10974 |
T10975 |
amod |
synaptic,plasticity |
R3125 |
T10975 |
T10973 |
pobj |
plasticity,of |
R3127 |
T10976 |
T10968 |
prep |
in,recognised |
R3128 |
T10977 |
T10978 |
det |
the,system |
R3129 |
T10978 |
T10976 |
pobj |
system,in |
R3130 |
T10979 |
T10978 |
amod |
adult,system |
R3131 |
T10980 |
T10978 |
amod |
nervous,system |
R3133 |
T10981 |
T10982 |
punct |
[,35 |
R3134 |
T10982 |
T10968 |
parataxis |
35,recognised |
R3135 |
T10983 |
T10937 |
punct |
],reported |
R3137 |
T11059 |
T11058 |
cc |
and,dysfunction |
R3138 |
T10984 |
T10937 |
punct |
.,reported |
R3139 |
T10986 |
T10987 |
nsubjpass |
Changes,thought |
R3140 |
T11060 |
T11061 |
amod |
complete,loss |
R3141 |
T10988 |
T10986 |
prep |
in,Changes |
R3142 |
T10989 |
T10990 |
compound |
neuron,excitability |
R3143 |
T11061 |
T11058 |
conj |
loss,dysfunction |
R3144 |
T10990 |
T10988 |
pobj |
excitability,in |
R3145 |
T10991 |
T10986 |
prep |
in,Changes |
R3146 |
T10992 |
T10993 |
det |
the,hippocampus |
R3147 |
T11062 |
T11061 |
prep |
of,loss |
R3148 |
T10993 |
T10991 |
pobj |
hippocampus,in |
R3149 |
T10994 |
T10986 |
punct |
", ",Changes |
R3150 |
T11063 |
T11064 |
preconj |
both,spontaneous |
R3151 |
T10995 |
T10996 |
amod |
such,as |
R3152 |
T10996 |
T10986 |
prep |
as,Changes |
R3153 |
T11064 |
T11065 |
amod |
spontaneous,currents |
R3154 |
T10997 |
T10996 |
pobj |
decreases,as |
R3155 |
T10998 |
T10997 |
prep |
in,decreases |
R3156 |
T10999 |
T11000 |
det |
the,post-burst |
R3157 |
T11065 |
T11062 |
pobj |
currents,of |
R3158 |
T11000 |
T10998 |
pobj |
post-burst,in |
R3159 |
T11001 |
T10997 |
prep |
after,decreases |
R3160 |
T11002 |
T11001 |
pobj |
hyperpolarization,after |
R3161 |
T11003 |
T11004 |
punct |
(,AHP |
R3162 |
T11004 |
T11002 |
parataxis |
AHP,hyperpolarization |
R3163 |
T11005 |
T11004 |
punct |
),AHP |
R3164 |
T11066 |
T11064 |
cc |
and,spontaneous |
R3165 |
T11006 |
T10987 |
punct |
", ",thought |
R3166 |
T11007 |
T10987 |
aux |
have,thought |
R3167 |
T11008 |
T10987 |
auxpass |
been,thought |
R3168 |
T11067 |
T11064 |
conj |
evoked,spontaneous |
R3169 |
T11009 |
T11010 |
aux |
to,affect |
R3170 |
T11010 |
T10987 |
xcomp |
affect,thought |
R3171 |
T11068 |
T11065 |
amod |
excitatory,currents |
R3172 |
T11011 |
T11012 |
amod |
long,term |
R3173 |
T11012 |
T11014 |
compound |
term,potentiation |
R3174 |
T11013 |
T11012 |
punct |
-,term |
R3175 |
T11069 |
T11065 |
amod |
postsynaptic,currents |
R3176 |
T11014 |
T11010 |
dobj |
potentiation,affect |
R3177 |
T11015 |
T11014 |
punct |
(,potentiation |
R3178 |
T11016 |
T11014 |
appos |
LTP,potentiation |
R3179 |
T11070 |
T11065 |
punct |
(,currents |
R3180 |
T11017 |
T11010 |
punct |
),affect |
R3181 |
T11018 |
T11019 |
punct |
[,36 |
R3182 |
T11019 |
T11010 |
parataxis |
36,affect |
R3183 |
T11020 |
T11019 |
punct |
],36 |
R3184 |
T11021 |
T11010 |
punct |
", ",affect |
R3185 |
T11022 |
T11023 |
det |
an,model |
R3186 |
T11071 |
T11065 |
appos |
EPSCs,currents |
R3187 |
T11023 |
T11010 |
npadvmod |
model,affect |
R3188 |
T11024 |
T11023 |
amod |
experimental,model |
R3189 |
T11025 |
T11023 |
prep |
of,model |
R3190 |
T11072 |
T11046 |
punct |
),showed |
R3191 |
T11026 |
T11027 |
det |
the,changes |
R3192 |
T11027 |
T11025 |
pobj |
changes,of |
R3193 |
T11028 |
T11027 |
amod |
synaptic,changes |
R3194 |
T11073 |
T11046 |
prep |
in,showed |
R3195 |
T11029 |
T11027 |
acl |
thought,changes |
R3196 |
T11030 |
T11031 |
aux |
to,underlie |
R3197 |
T11031 |
T11029 |
xcomp |
underlie,thought |
R3198 |
T11074 |
T11075 |
amod |
cerebellar,cells |
R3199 |
T11032 |
T11031 |
dobj |
learning,underlie |
R3200 |
T11033 |
T11032 |
cc |
and,learning |
R3201 |
T11034 |
T11032 |
conj |
memory,learning |
R3202 |
T11075 |
T11073 |
pobj |
cells,in |
R3203 |
T11035 |
T11036 |
punct |
[,37 |
R3204 |
T11036 |
T11029 |
parataxis |
37,thought |
R3205 |
T11037 |
T11036 |
punct |
],37 |
R3206 |
T11076 |
T11075 |
compound |
granule,cells |
R3207 |
T11038 |
T10987 |
punct |
.,thought |
R3208 |
T11077 |
T11078 |
punct |
[,38 |
R3209 |
T11040 |
T11041 |
nsubjpass |
It,reported |
R3210 |
T11042 |
T11041 |
aux |
has,reported |
R3211 |
T11078 |
T11046 |
parataxis |
38,showed |
R3212 |
T11043 |
T11041 |
advmod |
also,reported |
R3213 |
T11044 |
T11041 |
auxpass |
been,reported |
R3214 |
T11045 |
T11046 |
mark |
that,showed |
R3215 |
T11046 |
T11041 |
ccomp |
showed,reported |
R3216 |
T11079 |
T11078 |
punct |
],38 |
R3217 |
T11047 |
T11046 |
nsubj |
mice,showed |
R3218 |
T11048 |
T11047 |
acl |
lacking,mice |
R3219 |
T11049 |
T11050 |
compound |
NMDA,receptor |
R3220 |
T11080 |
T11041 |
punct |
.,reported |
R3221 |
T11050 |
T11048 |
dobj |
receptor,lacking |
R3222 |
T11051 |
T11048 |
prep |
for,lacking |
R3223 |
T11052 |
T11053 |
preconj |
both,subunits |
R3224 |
T11082 |
T11083 |
advmod |
Therefore,needed |
R3225 |
T11053 |
T11051 |
pobj |
subunits,for |
R3226 |
T11054 |
T11053 |
nmod |
NR2A,subunits |
R3227 |
T11055 |
T11054 |
cc |
and,NR2A |
R3228 |
T11056 |
T11054 |
conj |
NR2C,NR2A |
R3229 |
T11084 |
T11083 |
punct |
", ",needed |
R3230 |
T11057 |
T11058 |
compound |
motor,dysfunction |
R3231 |
T11058 |
T11046 |
dobj |
dysfunction,showed |
R3232 |
T11085 |
T11086 |
amod |
electrophyological,studies |
R3233 |
T11086 |
T11083 |
nsubjpass |
studies,needed |
R3234 |
T11087 |
T11088 |
aux |
to,enable |
R3236 |
T11088 |
T11086 |
advcl |
enable,studies |
R3239 |
T11089 |
T11088 |
dobj |
analysis,enable |
R3242 |
T11090 |
T11089 |
prep |
of,analysis |
R3246 |
T11091 |
T11092 |
amod |
synaptic,transmission |
R3250 |
T11092 |
T11090 |
pobj |
transmission,of |
R3253 |
T11093 |
T11092 |
cc |
and,transmission |
R3257 |
T11094 |
T11092 |
conj |
plasticity,transmission |
R3261 |
T11095 |
T11088 |
prep |
in,enable |
R3265 |
T11096 |
T11097 |
det |
the,hippocampus |
R3269 |
T11097 |
T11095 |
pobj |
hippocampus,in |
R3273 |
T11098 |
T11097 |
cc |
and,hippocampus |
R3275 |
T11099 |
T11097 |
conj |
cerebellum,hippocampus |
R3278 |
T11100 |
T11097 |
prep |
of,hippocampus |
R3282 |
T11101 |
T11102 |
npadvmod |
ADAM11,deficient |
R3284 |
T11102 |
T11104 |
amod |
deficient,mice |
R3286 |
T11103 |
T11102 |
punct |
-,deficient |
R3290 |
T11104 |
T11100 |
pobj |
mice,of |
R3294 |
T11105 |
T11083 |
aux |
will,needed |
R3298 |
T11106 |
T11083 |
auxpass |
be,needed |
R3300 |
T11107 |
T11083 |
punct |
.,needed |
R3303 |
T11109 |
T11110 |
det |
These,studies |
R3307 |
T11110 |
T11111 |
nsubj |
studies,clarify |
R3311 |
T11112 |
T11111 |
aux |
might,clarify |
R3316 |
T11113 |
T11114 |
mark |
whether,plays |
R3320 |
T11114 |
T11111 |
advcl |
plays,clarify |
R3323 |
T11115 |
T11114 |
nsubj |
ADAM11,plays |
R3326 |
T11116 |
T11117 |
det |
an,role |
R3329 |
T11117 |
T11114 |
dobj |
role,plays |
R3331 |
T11118 |
T11117 |
amod |
important,role |
R3333 |
T11119 |
T11117 |
nmod |
signalling,role |
R3336 |
T11120 |
T11119 |
cc |
or,signalling |
R3343 |
T11121 |
T11119 |
conj |
structural,signalling |
R3346 |
T11122 |
T11114 |
prep |
at,plays |
R3349 |
T11123 |
T11124 |
det |
the,level |
R3353 |
T11124 |
T11122 |
pobj |
level,at |
R3357 |
T11125 |
T11124 |
amod |
synaptic,level |
R3361 |
T11126 |
T11114 |
cc |
and,plays |
R3365 |
T11127 |
T11128 |
mark |
whether,participates |
R3367 |
T11128 |
T11114 |
conj |
participates,plays |
R3371 |
T11129 |
T11128 |
nsubj |
it,participates |
R3374 |
T11130 |
T11128 |
prep |
in,participates |
R3376 |
T11131 |
T11132 |
amod |
synaptic,regulation |
R3379 |
T11132 |
T11130 |
pobj |
regulation,in |
R3382 |
T11133 |
T11111 |
punct |
.,clarify |