PMC:1420314 / 14423-16444 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T10785 0-5 DT denotes These
T10786 6-13 NNS denotes results
T10787 14-21 VBP denotes suggest
T10788 22-26 IN denotes that
T10790 27-34 JJ denotes limited
T10792 35-40 NN denotes brain
T10791 41-46 NNS denotes sites
T10793 46-48 , denotes ,
T10794 48-54 RB denotes mainly
T10796 55-58 DT denotes the
T10795 59-70 NN denotes hippocampus
T10797 71-74 CC denotes and
T10798 75-85 NN denotes cerebellum
T10799 85-87 , denotes ,
T10800 87-92 MD denotes might
T10789 93-103 VB denotes contribute
T10801 104-106 IN denotes to
T10802 107-110 DT denotes the
T10804 111-119 JJ denotes dominant
T10803 120-129 NN denotes phenotype
T10805 129-131 , denotes ,
T10806 131-138 JJ denotes spatial
T10807 139-147 NN denotes learning
T10808 148-158 NN denotes impairment
T10809 159-162 CC denotes and
T10810 163-168 NN denotes motor
T10811 169-184 NN denotes discoordination
T10812 185-187 IN denotes in
T10813 188-194 NN denotes ADAM11
T10815 194-195 HYPH denotes -
T10814 195-204 JJ denotes deficient
T10816 205-209 NNS denotes mice
T10817 209-210 . denotes .
T10818 210-422 sentence denotes In situ hybridisation analysis has detected Adam11 gene expression in the pyramidal cells of CA1–CA3 fields and granule cells of the dentate gyrus in the hippocampus and in granular cells in the cerebellum [25].
T10819 211-213 FW denotes In
T10820 214-218 FW denotes situ
T10821 219-232 NN denotes hybridisation
T10822 233-241 NN denotes analysis
T10824 242-245 VBZ denotes has
T10823 246-254 VBN denotes detected
T10825 255-261 NN denotes Adam11
T10826 262-266 NN denotes gene
T10827 267-277 NN denotes expression
T10828 278-280 IN denotes in
T10829 281-284 DT denotes the
T10831 285-294 JJ denotes pyramidal
T10830 295-300 NNS denotes cells
T10832 301-303 IN denotes of
T10833 304-307 NN denotes CA1
T10835 307-308 SYM denotes
T10836 308-311 NN denotes CA3
T10834 312-318 NNS denotes fields
T10837 319-322 CC denotes and
T10838 323-330 NN denotes granule
T10839 331-336 NNS denotes cells
T10840 337-339 IN denotes of
T10841 340-343 DT denotes the
T10843 344-351 NN denotes dentate
T10842 352-357 NN denotes gyrus
T10844 358-360 IN denotes in
T10845 361-364 DT denotes the
T10846 365-376 NN denotes hippocampus
T10847 377-380 CC denotes and
T10848 381-383 IN denotes in
T10849 384-392 JJ denotes granular
T10850 393-398 NNS denotes cells
T10851 399-401 IN denotes in
T10852 402-405 DT denotes the
T10853 406-416 NN denotes cerebellum
T10854 417-418 -LRB- denotes [
T10855 418-420 CD denotes 25
T10856 420-421 -RRB- denotes ]
T10857 421-422 . denotes .
T10858 422-728 sentence denotes It is unlikely that morphological changes during development led to impairment of spatial learning and motor coordination, and morphological alterations in the cytoarchitecture of the hippocampus and cerebellum were not observed in ADAM11-deficient mice after histological investigation using HE staining.
T10859 423-425 PRP denotes It
T10860 426-428 VBZ denotes is
T10862 429-437 JJ denotes unlikely
T10863 438-442 IN denotes that
T10865 443-456 JJ denotes morphological
T10866 457-464 NNS denotes changes
T10867 465-471 IN denotes during
T10868 472-483 NN denotes development
T10864 484-487 VBD denotes led
T10869 488-490 IN denotes to
T10870 491-501 NN denotes impairment
T10871 502-504 IN denotes of
T10872 505-512 JJ denotes spatial
T10873 513-521 NN denotes learning
T10874 522-525 CC denotes and
T10875 526-531 NN denotes motor
T10876 532-544 NN denotes coordination
T10877 544-546 , denotes ,
T10878 546-549 CC denotes and
T10879 550-563 JJ denotes morphological
T10880 564-575 NNS denotes alterations
T10881 576-578 IN denotes in
T10882 579-582 DT denotes the
T10883 583-599 NN denotes cytoarchitecture
T10884 600-602 IN denotes of
T10885 603-606 DT denotes the
T10886 607-618 NN denotes hippocampus
T10887 619-622 CC denotes and
T10888 623-633 NN denotes cerebellum
T10889 634-638 VBD denotes were
T10890 639-642 RB denotes not
T10861 643-651 VBN denotes observed
T10891 652-654 IN denotes in
T10892 655-661 NN denotes ADAM11
T10894 661-662 HYPH denotes -
T10893 662-671 JJ denotes deficient
T10895 672-676 NNS denotes mice
T10896 677-682 IN denotes after
T10897 683-695 JJ denotes histological
T10898 696-709 NN denotes investigation
T10899 710-715 VBG denotes using
T10900 716-718 NN denotes HE
T10901 719-727 NN denotes staining
T10902 727-728 . denotes .
T10903 728-895 sentence denotes However, because it is thought that ADAM11 plays a role in neuron-neuron or neuron-glial cell interactions, a more precise morphological investigation will be needed.
T10904 729-736 RB denotes However
T10906 736-738 , denotes ,
T10907 738-745 IN denotes because
T10909 746-748 PRP denotes it
T10910 749-751 VBZ denotes is
T10908 752-759 VBN denotes thought
T10911 760-764 IN denotes that
T10913 765-771 NN denotes ADAM11
T10912 772-777 VBZ denotes plays
T10914 778-779 DT denotes a
T10915 780-784 NN denotes role
T10916 785-787 IN denotes in
T10917 788-794 NN denotes neuron
T10919 794-795 SYM denotes -
T10918 795-801 NN denotes neuron
T10921 802-804 CC denotes or
T10922 805-811 NN denotes neuron
T10924 811-812 SYM denotes -
T10925 812-817 JJ denotes glial
T10923 818-822 NN denotes cell
T10920 823-835 NNS denotes interactions
T10926 835-837 , denotes ,
T10927 837-838 DT denotes a
T10929 839-843 RBR denotes more
T10930 844-851 JJ denotes precise
T10931 852-865 JJ denotes morphological
T10928 866-879 NN denotes investigation
T10932 880-884 MD denotes will
T10933 885-887 VB denotes be
T10905 888-894 VBN denotes needed
T10934 894-895 . denotes .
T10935 895-1171 sentence denotes It has been reported that adhesion molecules, such as neural cell adhesion molecule (NCAM), are not only implicated in cell interactions during nervous system development, but are also recognised as important mediators of synaptic plasticity in the adult nervous system [35].
T10936 896-898 PRP denotes It
T10938 899-902 VBZ denotes has
T10939 903-907 VBN denotes been
T10937 908-916 VBN denotes reported
T10940 917-921 IN denotes that
T10942 922-930 NN denotes adhesion
T10943 931-940 NNS denotes molecules
T10944 940-942 , denotes ,
T10945 942-946 JJ denotes such
T10946 947-949 IN denotes as
T10947 950-956 JJ denotes neural
T10948 957-961 NN denotes cell
T10950 962-970 NN denotes adhesion
T10949 971-979 NN denotes molecule
T10951 980-981 -LRB- denotes (
T10952 981-985 NN denotes NCAM
T10953 985-986 -RRB- denotes )
T10954 986-988 , denotes ,
T10955 988-991 VBP denotes are
T10956 992-995 RB denotes not
T10957 996-1000 RB denotes only
T10941 1001-1011 VBN denotes implicated
T10958 1012-1014 IN denotes in
T10959 1015-1019 NN denotes cell
T10960 1020-1032 NNS denotes interactions
T10961 1033-1039 IN denotes during
T10962 1040-1047 JJ denotes nervous
T10963 1048-1054 NN denotes system
T10964 1055-1066 NN denotes development
T10965 1066-1068 , denotes ,
T10966 1068-1071 CC denotes but
T10967 1072-1075 VBP denotes are
T10969 1076-1080 RB denotes also
T10968 1081-1091 VBN denotes recognised
T10970 1092-1094 IN denotes as
T10971 1095-1104 JJ denotes important
T10972 1105-1114 NNS denotes mediators
T10973 1115-1117 IN denotes of
T10974 1118-1126 JJ denotes synaptic
T10975 1127-1137 NN denotes plasticity
T10976 1138-1140 IN denotes in
T10977 1141-1144 DT denotes the
T10979 1145-1150 JJ denotes adult
T10980 1151-1158 JJ denotes nervous
T10978 1159-1165 NN denotes system
T10981 1166-1167 -LRB- denotes [
T10982 1167-1169 CD denotes 35
T10983 1169-1170 -RRB- denotes ]
T10984 1170-1171 . denotes .
T10985 1171-1444 sentence denotes Changes in neuron excitability in the hippocampus, such as decreases in the post-burst after hyperpolarization (AHP), have been thought to affect long-term potentiation (LTP) [36], an experimental model of the synaptic changes thought to underlie learning and memory [37].
T10986 1172-1179 NNS denotes Changes
T10988 1180-1182 IN denotes in
T10989 1183-1189 NN denotes neuron
T10990 1190-1202 NN denotes excitability
T10991 1203-1205 IN denotes in
T10992 1206-1209 DT denotes the
T10993 1210-1221 NN denotes hippocampus
T10994 1221-1223 , denotes ,
T10995 1223-1227 JJ denotes such
T10996 1228-1230 IN denotes as
T10997 1231-1240 NNS denotes decreases
T10998 1241-1243 IN denotes in
T10999 1244-1247 DT denotes the
T11000 1248-1258 JJ denotes post-burst
T11001 1259-1264 IN denotes after
T11002 1265-1282 NN denotes hyperpolarization
T11003 1283-1284 -LRB- denotes (
T11004 1284-1287 NN denotes AHP
T11005 1287-1288 -RRB- denotes )
T11006 1288-1290 , denotes ,
T11007 1290-1294 VBP denotes have
T11008 1295-1299 VBN denotes been
T10987 1300-1307 VBN denotes thought
T11009 1308-1310 TO denotes to
T11010 1311-1317 VB denotes affect
T11011 1318-1322 JJ denotes long
T11013 1322-1323 HYPH denotes -
T11012 1323-1327 NN denotes term
T11014 1328-1340 NN denotes potentiation
T11015 1341-1342 -LRB- denotes (
T11016 1342-1345 NN denotes LTP
T11017 1345-1346 -RRB- denotes )
T11018 1347-1348 -LRB- denotes [
T11019 1348-1350 CD denotes 36
T11020 1350-1351 -RRB- denotes ]
T11021 1351-1353 , denotes ,
T11022 1353-1355 DT denotes an
T11024 1356-1368 JJ denotes experimental
T11023 1369-1374 NN denotes model
T11025 1375-1377 IN denotes of
T11026 1378-1381 DT denotes the
T11028 1382-1390 JJ denotes synaptic
T11027 1391-1398 NNS denotes changes
T11029 1399-1406 VBN denotes thought
T11030 1407-1409 TO denotes to
T11031 1410-1418 VB denotes underlie
T11032 1419-1427 NN denotes learning
T11033 1428-1431 CC denotes and
T11034 1432-1438 NN denotes memory
T11035 1439-1440 -LRB- denotes [
T11036 1440-1442 CD denotes 37
T11037 1442-1443 -RRB- denotes ]
T11038 1443-1444 . denotes .
T11039 1444-1683 sentence denotes It has also been reported that mice lacking NMDA receptor for both NR2A and NR2C subunits showed motor dysfunction and complete loss of both spontaneous and evoked excitatory postsynaptic currents (EPSCs) in cerebellar granule cells [38].
T11040 1445-1447 PRP denotes It
T11042 1448-1451 VBZ denotes has
T11043 1452-1456 RB denotes also
T11044 1457-1461 VBN denotes been
T11041 1462-1470 VBN denotes reported
T11045 1471-1475 IN denotes that
T11047 1476-1480 NNS denotes mice
T11048 1481-1488 VBG denotes lacking
T11049 1489-1493 NN denotes NMDA
T11050 1494-1502 NN denotes receptor
T11051 1503-1506 IN denotes for
T11052 1507-1511 CC denotes both
T11054 1512-1516 NN denotes NR2A
T11055 1517-1520 CC denotes and
T11056 1521-1525 NN denotes NR2C
T11053 1526-1534 NNS denotes subunits
T11046 1535-1541 VBD denotes showed
T11057 1542-1547 NN denotes motor
T11058 1548-1559 NN denotes dysfunction
T11059 1560-1563 CC denotes and
T11060 1564-1572 JJ denotes complete
T11061 1573-1577 NN denotes loss
T11062 1578-1580 IN denotes of
T11063 1581-1585 CC denotes both
T11064 1586-1597 JJ denotes spontaneous
T11066 1598-1601 CC denotes and
T11067 1602-1608 VBN denotes evoked
T11068 1609-1619 JJ denotes excitatory
T11069 1620-1632 JJ denotes postsynaptic
T11065 1633-1641 NNS denotes currents
T11070 1642-1643 -LRB- denotes (
T11071 1643-1648 NNS denotes EPSCs
T11072 1648-1649 -RRB- denotes )
T11073 1650-1652 IN denotes in
T11074 1653-1663 JJ denotes cerebellar
T11076 1664-1671 NN denotes granule
T11075 1672-1677 NNS denotes cells
T11077 1678-1679 -LRB- denotes [
T11078 1679-1681 CD denotes 38
T11079 1681-1682 -RRB- denotes ]
T11080 1682-1683 . denotes .
T11081 1683-1855 sentence denotes Therefore, electrophyological studies to enable analysis of synaptic transmission and plasticity in the hippocampus and cerebellum of ADAM11-deficient mice will be needed.
T11082 1684-1693 RB denotes Therefore
T11084 1693-1695 , denotes ,
T11085 1695-1713 JJ denotes electrophyological
T11086 1714-1721 NNS denotes studies
T11087 1722-1724 TO denotes to
T11088 1725-1731 VB denotes enable
T11089 1732-1740 NN denotes analysis
T11090 1741-1743 IN denotes of
T11091 1744-1752 JJ denotes synaptic
T11092 1753-1765 NN denotes transmission
T11093 1766-1769 CC denotes and
T11094 1770-1780 NN denotes plasticity
T11095 1781-1783 IN denotes in
T11096 1784-1787 DT denotes the
T11097 1788-1799 NN denotes hippocampus
T11098 1800-1803 CC denotes and
T11099 1804-1814 NN denotes cerebellum
T11100 1815-1817 IN denotes of
T11101 1818-1824 NN denotes ADAM11
T11103 1824-1825 HYPH denotes -
T11102 1825-1834 JJ denotes deficient
T11104 1835-1839 NNS denotes mice
T11105 1840-1844 MD denotes will
T11106 1845-1847 VB denotes be
T11083 1848-1854 VBN denotes needed
T11107 1854-1855 . denotes .
T11108 1855-2021 sentence denotes These studies might clarify whether ADAM11 plays an important signalling or structural role at the synaptic level and whether it participates in synaptic regulation.
T11109 1856-1861 DT denotes These
T11110 1862-1869 NNS denotes studies
T11112 1870-1875 MD denotes might
T11111 1876-1883 VB denotes clarify
T11113 1884-1891 IN denotes whether
T11115 1892-1898 NN denotes ADAM11
T11114 1899-1904 VBZ denotes plays
T11116 1905-1907 DT denotes an
T11118 1908-1917 JJ denotes important
T11119 1918-1928 NN denotes signalling
T11120 1929-1931 CC denotes or
T11121 1932-1942 JJ denotes structural
T11117 1943-1947 NN denotes role
T11122 1948-1950 IN denotes at
T11123 1951-1954 DT denotes the
T11125 1955-1963 JJ denotes synaptic
T11124 1964-1969 NN denotes level
T11126 1970-1973 CC denotes and
T11127 1974-1981 IN denotes whether
T11129 1982-1984 PRP denotes it
T11128 1985-1997 VBZ denotes participates
T11130 1998-2000 IN denotes in
T11131 2001-2009 JJ denotes synaptic
T11132 2010-2020 NN denotes regulation
T11133 2020-2021 . denotes .
R2874 T10785 T10786 det These,results
R2876 T10786 T10787 nsubj results,suggest
R2877 T10788 T10789 mark that,contribute
R2879 T10789 T10787 ccomp contribute,suggest
R2880 T10790 T10791 amod limited,sites
R2882 T10791 T10789 nsubj sites,contribute
R2883 T10792 T10791 compound brain,sites
R2884 T10793 T10791 punct ", ",sites
R2886 T10794 T10795 advmod mainly,hippocampus
R2887 T10795 T10791 appos hippocampus,sites
R2888 T10796 T10795 det the,hippocampus
R2890 T10797 T10795 cc and,hippocampus
R2891 T10798 T10795 conj cerebellum,hippocampus
R2892 T10799 T10789 punct ", ",contribute
R2894 T10800 T10789 aux might,contribute
R2895 T10801 T10789 prep to,contribute
R2896 T10802 T10803 det the,phenotype
R2898 T10803 T10801 pobj phenotype,to
R2899 T10804 T10803 amod dominant,phenotype
R2900 T10805 T10803 punct ", ",phenotype
R2902 T10806 T10807 amod spatial,learning
R2903 T10807 T10808 compound learning,impairment
R2904 T10808 T10803 appos impairment,phenotype
R2906 T10809 T10808 cc and,impairment
R2907 T10810 T10811 compound motor,discoordination
R2908 T10811 T10808 conj discoordination,impairment
R2910 T10812 T10789 prep in,contribute
R2911 T10813 T10814 npadvmod ADAM11,deficient
R2915 T10814 T10816 amod deficient,mice
R2917 T10815 T10814 punct -,deficient
R2918 T10816 T10812 pobj mice,in
R2919 T10817 T10787 punct .,suggest
R2921 T10819 T10820 advmod In,situ
R2922 T10820 T10821 amod situ,hybridisation
R2923 T10821 T10822 compound hybridisation,analysis
R2925 T10822 T10823 nsubj analysis,detected
R2926 T10824 T10823 aux has,detected
R2928 T10825 T10826 compound Adam11,gene
R2929 T10826 T10827 compound gene,expression
R2930 T10827 T10823 dobj expression,detected
R2932 T10828 T10823 prep in,detected
R2933 T10829 T10830 det the,cells
R2935 T10830 T10828 pobj cells,in
R2936 T10831 T10830 amod pyramidal,cells
R2937 T10832 T10830 prep of,cells
R2939 T10833 T10834 nmod CA1,fields
R2940 T10834 T10832 pobj fields,of
R2941 T10835 T10836 punct –,CA3
R2943 T10836 T10833 prep CA3,CA1
R2944 T10837 T10830 cc and,cells
R2946 T10838 T10839 compound granule,cells
R2947 T10839 T10830 conj cells,cells
R2948 T10840 T10839 prep of,cells
R2950 T10841 T10842 det the,gyrus
R2951 T10842 T10840 pobj gyrus,of
R2952 T10843 T10842 compound dentate,gyrus
R2954 T10844 T10842 prep in,gyrus
R2955 T10845 T10846 det the,hippocampus
R2956 T10846 T10844 pobj hippocampus,in
R2960 T10847 T10844 cc and,in
R2961 T10848 T10844 conj in,in
R2963 T10849 T10850 amod granular,cells
R2964 T10850 T10848 pobj cells,in
R2965 T10851 T10850 prep in,cells
R2966 T10852 T10853 det the,cerebellum
R2968 T10853 T10851 pobj cerebellum,in
R2969 T10854 T10855 punct [,25
R2971 T10855 T10823 parataxis 25,detected
R2972 T10856 T10855 punct ],25
R2973 T10857 T10823 punct .,detected
R2974 T10859 T10860 nsubj It,is
R2975 T10860 T10861 ccomp is,observed
R2976 T10862 T10860 acomp unlikely,is
R2978 T10863 T10864 mark that,led
R2979 T10864 T10860 ccomp led,is
R2980 T10865 T10866 amod morphological,changes
R2982 T10866 T10864 nsubj changes,led
R2983 T10867 T10866 prep during,changes
R2984 T10868 T10867 pobj development,during
R2986 T10869 T10864 prep to,led
R2987 T10870 T10869 pobj impairment,to
R2988 T10871 T10870 prep of,impairment
R2990 T10872 T10873 amod spatial,learning
R2991 T10873 T10871 pobj learning,of
R2992 T10874 T10873 cc and,learning
R2994 T10875 T10876 compound motor,coordination
R2995 T10876 T10873 conj coordination,learning
R2996 T10877 T10861 punct ", ",observed
R2998 T10878 T10861 cc and,observed
R2999 T10879 T10880 amod morphological,alterations
R3000 T10880 T10861 nsubjpass alterations,observed
R3002 T10881 T10880 prep in,alterations
R3003 T10882 T10883 det the,cytoarchitecture
R3004 T10883 T10881 pobj cytoarchitecture,in
R3006 T10884 T10883 prep of,cytoarchitecture
R3007 T10885 T10886 det the,hippocampus
R3008 T10886 T10884 pobj hippocampus,of
R3010 T10887 T10886 cc and,hippocampus
R3011 T10888 T10886 conj cerebellum,hippocampus
R3012 T10889 T10861 auxpass were,observed
R3014 T10890 T10861 neg not,observed
R3015 T10891 T10861 prep in,observed
R3016 T10892 T10893 npadvmod ADAM11,deficient
R3018 T10893 T10895 amod deficient,mice
R3019 T10894 T10893 punct -,deficient
R3020 T10895 T10891 pobj mice,in
R3022 T10896 T10861 prep after,observed
R3023 T10897 T10898 amod histological,investigation
R3024 T10898 T10896 pobj investigation,after
R3026 T10899 T10898 acl using,investigation
R3028 T10900 T10901 compound HE,staining
R3029 T10901 T10899 dobj staining,using
R3031 T10902 T10861 punct .,observed
R3032 T10904 T10905 advmod However,needed
R3034 T10906 T10905 punct ", ",needed
R3036 T10907 T10908 mark because,thought
R3037 T10908 T10905 advcl thought,needed
R3038 T10909 T10908 nsubjpass it,thought
R3040 T10910 T10908 auxpass is,thought
R3041 T10911 T10912 mark that,plays
R3042 T10912 T10908 ccomp plays,thought
R3044 T10913 T10912 nsubj ADAM11,plays
R3045 T10914 T10915 det a,role
R3047 T10915 T10912 dobj role,plays
R3048 T10916 T10912 prep in,plays
R3049 T10917 T10918 nmod neuron,neuron
R3051 T10918 T10920 nmod neuron,interactions
R3052 T10919 T10918 punct -,neuron
R3053 T10920 T10916 pobj interactions,in
R3054 T10921 T10918 cc or,neuron
R3056 T10922 T10923 nmod neuron,cell
R3057 T10923 T10918 conj cell,neuron
R3058 T10924 T10923 punct -,cell
R3060 T10925 T10923 amod glial,cell
R3061 T10926 T10905 punct ", ",needed
R3062 T10927 T10928 det a,investigation
R3064 T10928 T10905 nsubjpass investigation,needed
R3065 T10929 T10930 advmod more,precise
R3066 T10930 T10928 amod precise,investigation
R3068 T10931 T10928 amod morphological,investigation
R3069 T10932 T10905 aux will,needed
R3070 T10933 T10905 auxpass be,needed
R3072 T10934 T10905 punct .,needed
R3073 T10936 T10937 nsubjpass It,reported
R3075 T10938 T10937 aux has,reported
R3076 T10939 T10937 auxpass been,reported
R3077 T10940 T10941 mark that,implicated
R3078 T10941 T10937 ccomp implicated,reported
R3080 T10942 T10943 compound adhesion,molecules
R3081 T10943 T10941 nsubjpass molecules,implicated
R3082 T10944 T10943 punct ", ",molecules
R3084 T10945 T10946 amod such,as
R3085 T10946 T10943 prep as,molecules
R3086 T10947 T10948 amod neural,cell
R3088 T10948 T10949 compound cell,molecule
R3089 T10949 T10946 pobj molecule,as
R3090 T10950 T10949 compound adhesion,molecule
R3091 T10951 T10949 punct (,molecule
R3092 T10952 T10949 appos NCAM,molecule
R3095 T10953 T10941 punct ),implicated
R3097 T10954 T10941 punct ", ",implicated
R3098 T10955 T10941 auxpass are,implicated
R3100 T10956 T10941 preconj not,implicated
R3101 T10957 T10956 advmod only,not
R3102 T10958 T10941 prep in,implicated
R3104 T10959 T10960 compound cell,interactions
R3105 T10960 T10958 pobj interactions,in
R3106 T10961 T10941 prep during,implicated
R3108 T10962 T10963 amod nervous,system
R3109 T10963 T10964 compound system,development
R3110 T10964 T10961 pobj development,during
R3112 T10965 T10941 punct ", ",implicated
R3113 T10966 T10941 cc but,implicated
R3114 T10967 T10968 auxpass are,recognised
R3116 T10968 T10941 conj recognised,implicated
R3117 T10969 T10968 advmod also,recognised
R3119 T10970 T10968 prep as,recognised
R3120 T10971 T10972 amod important,mediators
R3121 T10972 T10970 pobj mediators,as
R3123 T10973 T10972 prep of,mediators
R3124 T10974 T10975 amod synaptic,plasticity
R3125 T10975 T10973 pobj plasticity,of
R3127 T10976 T10968 prep in,recognised
R3128 T10977 T10978 det the,system
R3129 T10978 T10976 pobj system,in
R3130 T10979 T10978 amod adult,system
R3131 T10980 T10978 amod nervous,system
R3133 T10981 T10982 punct [,35
R3134 T10982 T10968 parataxis 35,recognised
R3135 T10983 T10937 punct ],reported
R3137 T11059 T11058 cc and,dysfunction
R3138 T10984 T10937 punct .,reported
R3139 T10986 T10987 nsubjpass Changes,thought
R3140 T11060 T11061 amod complete,loss
R3141 T10988 T10986 prep in,Changes
R3142 T10989 T10990 compound neuron,excitability
R3143 T11061 T11058 conj loss,dysfunction
R3144 T10990 T10988 pobj excitability,in
R3145 T10991 T10986 prep in,Changes
R3146 T10992 T10993 det the,hippocampus
R3147 T11062 T11061 prep of,loss
R3148 T10993 T10991 pobj hippocampus,in
R3149 T10994 T10986 punct ", ",Changes
R3150 T11063 T11064 preconj both,spontaneous
R3151 T10995 T10996 amod such,as
R3152 T10996 T10986 prep as,Changes
R3153 T11064 T11065 amod spontaneous,currents
R3154 T10997 T10996 pobj decreases,as
R3155 T10998 T10997 prep in,decreases
R3156 T10999 T11000 det the,post-burst
R3157 T11065 T11062 pobj currents,of
R3158 T11000 T10998 pobj post-burst,in
R3159 T11001 T10997 prep after,decreases
R3160 T11002 T11001 pobj hyperpolarization,after
R3161 T11003 T11004 punct (,AHP
R3162 T11004 T11002 parataxis AHP,hyperpolarization
R3163 T11005 T11004 punct ),AHP
R3164 T11066 T11064 cc and,spontaneous
R3165 T11006 T10987 punct ", ",thought
R3166 T11007 T10987 aux have,thought
R3167 T11008 T10987 auxpass been,thought
R3168 T11067 T11064 conj evoked,spontaneous
R3169 T11009 T11010 aux to,affect
R3170 T11010 T10987 xcomp affect,thought
R3171 T11068 T11065 amod excitatory,currents
R3172 T11011 T11012 amod long,term
R3173 T11012 T11014 compound term,potentiation
R3174 T11013 T11012 punct -,term
R3175 T11069 T11065 amod postsynaptic,currents
R3176 T11014 T11010 dobj potentiation,affect
R3177 T11015 T11014 punct (,potentiation
R3178 T11016 T11014 appos LTP,potentiation
R3179 T11070 T11065 punct (,currents
R3180 T11017 T11010 punct ),affect
R3181 T11018 T11019 punct [,36
R3182 T11019 T11010 parataxis 36,affect
R3183 T11020 T11019 punct ],36
R3184 T11021 T11010 punct ", ",affect
R3185 T11022 T11023 det an,model
R3186 T11071 T11065 appos EPSCs,currents
R3187 T11023 T11010 npadvmod model,affect
R3188 T11024 T11023 amod experimental,model
R3189 T11025 T11023 prep of,model
R3190 T11072 T11046 punct ),showed
R3191 T11026 T11027 det the,changes
R3192 T11027 T11025 pobj changes,of
R3193 T11028 T11027 amod synaptic,changes
R3194 T11073 T11046 prep in,showed
R3195 T11029 T11027 acl thought,changes
R3196 T11030 T11031 aux to,underlie
R3197 T11031 T11029 xcomp underlie,thought
R3198 T11074 T11075 amod cerebellar,cells
R3199 T11032 T11031 dobj learning,underlie
R3200 T11033 T11032 cc and,learning
R3201 T11034 T11032 conj memory,learning
R3202 T11075 T11073 pobj cells,in
R3203 T11035 T11036 punct [,37
R3204 T11036 T11029 parataxis 37,thought
R3205 T11037 T11036 punct ],37
R3206 T11076 T11075 compound granule,cells
R3207 T11038 T10987 punct .,thought
R3208 T11077 T11078 punct [,38
R3209 T11040 T11041 nsubjpass It,reported
R3210 T11042 T11041 aux has,reported
R3211 T11078 T11046 parataxis 38,showed
R3212 T11043 T11041 advmod also,reported
R3213 T11044 T11041 auxpass been,reported
R3214 T11045 T11046 mark that,showed
R3215 T11046 T11041 ccomp showed,reported
R3216 T11079 T11078 punct ],38
R3217 T11047 T11046 nsubj mice,showed
R3218 T11048 T11047 acl lacking,mice
R3219 T11049 T11050 compound NMDA,receptor
R3220 T11080 T11041 punct .,reported
R3221 T11050 T11048 dobj receptor,lacking
R3222 T11051 T11048 prep for,lacking
R3223 T11052 T11053 preconj both,subunits
R3224 T11082 T11083 advmod Therefore,needed
R3225 T11053 T11051 pobj subunits,for
R3226 T11054 T11053 nmod NR2A,subunits
R3227 T11055 T11054 cc and,NR2A
R3228 T11056 T11054 conj NR2C,NR2A
R3229 T11084 T11083 punct ", ",needed
R3230 T11057 T11058 compound motor,dysfunction
R3231 T11058 T11046 dobj dysfunction,showed
R3232 T11085 T11086 amod electrophyological,studies
R3233 T11086 T11083 nsubjpass studies,needed
R3234 T11087 T11088 aux to,enable
R3236 T11088 T11086 advcl enable,studies
R3239 T11089 T11088 dobj analysis,enable
R3242 T11090 T11089 prep of,analysis
R3246 T11091 T11092 amod synaptic,transmission
R3250 T11092 T11090 pobj transmission,of
R3253 T11093 T11092 cc and,transmission
R3257 T11094 T11092 conj plasticity,transmission
R3261 T11095 T11088 prep in,enable
R3265 T11096 T11097 det the,hippocampus
R3269 T11097 T11095 pobj hippocampus,in
R3273 T11098 T11097 cc and,hippocampus
R3275 T11099 T11097 conj cerebellum,hippocampus
R3278 T11100 T11097 prep of,hippocampus
R3282 T11101 T11102 npadvmod ADAM11,deficient
R3284 T11102 T11104 amod deficient,mice
R3286 T11103 T11102 punct -,deficient
R3290 T11104 T11100 pobj mice,of
R3294 T11105 T11083 aux will,needed
R3298 T11106 T11083 auxpass be,needed
R3300 T11107 T11083 punct .,needed
R3303 T11109 T11110 det These,studies
R3307 T11110 T11111 nsubj studies,clarify
R3311 T11112 T11111 aux might,clarify
R3316 T11113 T11114 mark whether,plays
R3320 T11114 T11111 advcl plays,clarify
R3323 T11115 T11114 nsubj ADAM11,plays
R3326 T11116 T11117 det an,role
R3329 T11117 T11114 dobj role,plays
R3331 T11118 T11117 amod important,role
R3333 T11119 T11117 nmod signalling,role
R3336 T11120 T11119 cc or,signalling
R3343 T11121 T11119 conj structural,signalling
R3346 T11122 T11114 prep at,plays
R3349 T11123 T11124 det the,level
R3353 T11124 T11122 pobj level,at
R3357 T11125 T11124 amod synaptic,level
R3361 T11126 T11114 cc and,plays
R3365 T11127 T11128 mark whether,participates
R3367 T11128 T11114 conj participates,plays
R3371 T11129 T11128 nsubj it,participates
R3374 T11130 T11128 prep in,participates
R3376 T11131 T11132 amod synaptic,regulation
R3379 T11132 T11130 pobj regulation,in
R3382 T11133 T11111 punct .,clarify