Id |
Subject |
Object |
Predicate |
Lexical cue |
T227 |
6-11 |
NN |
denotes |
BRCA2 |
T228 |
12-15 |
VBD |
denotes |
was |
T229 |
16-19 |
DT |
denotes |
the |
T231 |
20-26 |
JJ |
denotes |
second |
T232 |
27-33 |
NN |
denotes |
breast |
T233 |
34-40 |
NN |
denotes |
cancer |
T234 |
41-55 |
NN |
denotes |
susceptibility |
T230 |
56-60 |
NN |
denotes |
gene |
T235 |
61-63 |
TO |
denotes |
to |
T237 |
64-66 |
VB |
denotes |
be |
T236 |
67-77 |
VBN |
denotes |
discovered |
T238 |
77-79 |
, |
denotes |
, |
T239 |
79-82 |
CC |
denotes |
and |
T240 |
83-86 |
VBD |
denotes |
was |
T241 |
87-95 |
VBN |
denotes |
isolated |
T242 |
96-103 |
IN |
denotes |
through |
T243 |
104-114 |
JJ |
denotes |
positional |
T244 |
115-122 |
NN |
denotes |
cloning |
T245 |
123-128 |
VBG |
denotes |
using |
T246 |
129-133 |
NNS |
denotes |
data |
T247 |
134-138 |
IN |
denotes |
from |
T248 |
139-147 |
NNS |
denotes |
families |
T249 |
148-152 |
IN |
denotes |
with |
T250 |
153-162 |
JJ |
denotes |
inherited |
T252 |
163-169 |
NN |
denotes |
breast |
T251 |
170-176 |
NN |
denotes |
cancer |
T253 |
177-178 |
-LRB- |
denotes |
[ |
T254 |
178-179 |
CD |
denotes |
4 |
T255 |
179-180 |
-RRB- |
denotes |
] |
T256 |
180-181 |
. |
denotes |
. |
T257 |
181-318 |
sentence |
denotes |
Cells with mutant BRCA2 protein are, like many cancer cells, genetically unstable and accumulate gross chromosomal rearrangements [5,6]. |
T258 |
182-187 |
NNS |
denotes |
Cells |
T260 |
188-192 |
IN |
denotes |
with |
T261 |
193-199 |
JJ |
denotes |
mutant |
T263 |
200-205 |
NN |
denotes |
BRCA2 |
T262 |
206-213 |
NN |
denotes |
protein |
T259 |
214-217 |
VBP |
denotes |
are |
T264 |
217-219 |
, |
denotes |
, |
T265 |
219-223 |
IN |
denotes |
like |
T266 |
224-228 |
JJ |
denotes |
many |
T268 |
229-235 |
NN |
denotes |
cancer |
T267 |
236-241 |
NNS |
denotes |
cells |
T269 |
241-243 |
, |
denotes |
, |
T270 |
243-254 |
RB |
denotes |
genetically |
T271 |
255-263 |
JJ |
denotes |
unstable |
T272 |
264-267 |
CC |
denotes |
and |
T273 |
268-278 |
VBP |
denotes |
accumulate |
T274 |
279-284 |
JJ |
denotes |
gross |
T276 |
285-296 |
JJ |
denotes |
chromosomal |
T275 |
297-311 |
NNS |
denotes |
rearrangements |
T277 |
312-313 |
-LRB- |
denotes |
[ |
T279 |
313-314 |
CD |
denotes |
5 |
T280 |
314-315 |
, |
denotes |
, |
T278 |
315-316 |
CD |
denotes |
6 |
T281 |
316-317 |
-RRB- |
denotes |
] |
T282 |
317-318 |
. |
denotes |
. |
T283 |
318-565 |
sentence |
denotes |
The sequence of this large protein (3418 amino acids) offers very little clue to its function, although there are eight repeated segments (termed BRC repeats) in the middle of the protein that are highly conserved among mammalian orthologs [7,8]. |
T284 |
319-322 |
DT |
denotes |
The |
T285 |
323-331 |
NN |
denotes |
sequence |
T287 |
332-334 |
IN |
denotes |
of |
T288 |
335-339 |
DT |
denotes |
this |
T290 |
340-345 |
JJ |
denotes |
large |
T289 |
346-353 |
NN |
denotes |
protein |
T291 |
354-355 |
-LRB- |
denotes |
( |
T292 |
355-359 |
CD |
denotes |
3418 |
T294 |
360-365 |
NN |
denotes |
amino |
T293 |
366-371 |
NNS |
denotes |
acids |
T295 |
371-372 |
-RRB- |
denotes |
) |
T286 |
373-379 |
VBZ |
denotes |
offers |
T296 |
380-384 |
RB |
denotes |
very |
T298 |
385-391 |
JJ |
denotes |
little |
T297 |
392-396 |
NN |
denotes |
clue |
T299 |
397-399 |
IN |
denotes |
to |
T300 |
400-403 |
PRP$ |
denotes |
its |
T301 |
404-412 |
NN |
denotes |
function |
T302 |
412-414 |
, |
denotes |
, |
T303 |
414-422 |
IN |
denotes |
although |
T305 |
423-428 |
EX |
denotes |
there |
T304 |
429-432 |
VBP |
denotes |
are |
T306 |
433-438 |
CD |
denotes |
eight |
T308 |
439-447 |
JJ |
denotes |
repeated |
T307 |
448-456 |
NNS |
denotes |
segments |
T309 |
457-458 |
-LRB- |
denotes |
( |
T310 |
458-464 |
VBN |
denotes |
termed |
T311 |
465-468 |
NN |
denotes |
BRC |
T312 |
469-476 |
NNS |
denotes |
repeats |
T313 |
476-477 |
-RRB- |
denotes |
) |
T314 |
478-480 |
IN |
denotes |
in |
T315 |
481-484 |
DT |
denotes |
the |
T316 |
485-491 |
NN |
denotes |
middle |
T317 |
492-494 |
IN |
denotes |
of |
T318 |
495-498 |
DT |
denotes |
the |
T319 |
499-506 |
NN |
denotes |
protein |
T320 |
507-511 |
WDT |
denotes |
that |
T321 |
512-515 |
VBP |
denotes |
are |
T322 |
516-522 |
RB |
denotes |
highly |
T323 |
523-532 |
VBN |
denotes |
conserved |
T324 |
533-538 |
IN |
denotes |
among |
T325 |
539-548 |
JJ |
denotes |
mammalian |
T326 |
549-558 |
NNS |
denotes |
orthologs |
T327 |
559-560 |
-LRB- |
denotes |
[ |
T329 |
560-561 |
CD |
denotes |
7 |
T330 |
561-562 |
, |
denotes |
, |
T328 |
562-563 |
CD |
denotes |
8 |
T331 |
563-564 |
-RRB- |
denotes |
] |
T332 |
564-565 |
. |
denotes |
. |
R135 |
T227 |
T228 |
nsubj |
BRCA2,was |
R136 |
T229 |
T230 |
det |
the,gene |
R137 |
T230 |
T228 |
attr |
gene,was |
R138 |
T231 |
T230 |
amod |
second,gene |
R139 |
T232 |
T233 |
compound |
breast,cancer |
R140 |
T233 |
T234 |
compound |
cancer,susceptibility |
R141 |
T234 |
T230 |
compound |
susceptibility,gene |
R142 |
T235 |
T236 |
aux |
to,discovered |
R143 |
T236 |
T230 |
advcl |
discovered,gene |
R144 |
T237 |
T236 |
auxpass |
be,discovered |
R145 |
T238 |
T228 |
punct |
", ",was |
R146 |
T239 |
T228 |
cc |
and,was |
R147 |
T240 |
T241 |
auxpass |
was,isolated |
R148 |
T241 |
T228 |
conj |
isolated,was |
R149 |
T242 |
T241 |
prep |
through,isolated |
R150 |
T243 |
T244 |
amod |
positional,cloning |
R151 |
T244 |
T242 |
pobj |
cloning,through |
R152 |
T245 |
T241 |
advcl |
using,isolated |
R153 |
T246 |
T245 |
dobj |
data,using |
R154 |
T247 |
T246 |
prep |
from,data |
R155 |
T248 |
T247 |
pobj |
families,from |
R156 |
T249 |
T248 |
prep |
with,families |
R157 |
T250 |
T251 |
amod |
inherited,cancer |
R158 |
T251 |
T249 |
pobj |
cancer,with |
R159 |
T252 |
T251 |
compound |
breast,cancer |
R160 |
T253 |
T254 |
punct |
[,4 |
R161 |
T254 |
T241 |
parataxis |
4,isolated |
R162 |
T255 |
T254 |
punct |
],4 |
R163 |
T256 |
T228 |
punct |
.,was |
R164 |
T258 |
T259 |
nsubj |
Cells,are |
R165 |
T260 |
T258 |
prep |
with,Cells |
R166 |
T261 |
T262 |
amod |
mutant,protein |
R167 |
T262 |
T260 |
pobj |
protein,with |
R168 |
T263 |
T262 |
compound |
BRCA2,protein |
R169 |
T264 |
T259 |
punct |
", ",are |
R170 |
T265 |
T259 |
prep |
like,are |
R171 |
T266 |
T267 |
amod |
many,cells |
R172 |
T267 |
T265 |
pobj |
cells,like |
R173 |
T268 |
T267 |
compound |
cancer,cells |
R174 |
T269 |
T259 |
punct |
", ",are |
R175 |
T270 |
T271 |
advmod |
genetically,unstable |
R176 |
T271 |
T259 |
acomp |
unstable,are |
R177 |
T272 |
T259 |
cc |
and,are |
R178 |
T273 |
T259 |
conj |
accumulate,are |
R179 |
T274 |
T275 |
amod |
gross,rearrangements |
R180 |
T275 |
T273 |
dobj |
rearrangements,accumulate |
R181 |
T276 |
T275 |
amod |
chromosomal,rearrangements |
R182 |
T277 |
T278 |
punct |
[,6 |
R183 |
T278 |
T273 |
parataxis |
6,accumulate |
R184 |
T279 |
T278 |
nummod |
5,6 |
R185 |
T280 |
T278 |
punct |
",",6 |
R186 |
T281 |
T278 |
punct |
],6 |
R187 |
T282 |
T259 |
punct |
.,are |
R188 |
T284 |
T285 |
det |
The,sequence |
R189 |
T285 |
T286 |
nsubj |
sequence,offers |
R190 |
T287 |
T285 |
prep |
of,sequence |
R191 |
T288 |
T289 |
det |
this,protein |
R192 |
T289 |
T287 |
pobj |
protein,of |
R193 |
T290 |
T289 |
amod |
large,protein |
R194 |
T291 |
T285 |
punct |
(,sequence |
R195 |
T292 |
T293 |
nummod |
3418,acids |
R196 |
T293 |
T285 |
appos |
acids,sequence |
R197 |
T294 |
T293 |
compound |
amino,acids |
R198 |
T295 |
T286 |
punct |
),offers |
R199 |
T296 |
T297 |
advmod |
very,clue |
R200 |
T297 |
T286 |
dobj |
clue,offers |
R201 |
T298 |
T297 |
amod |
little,clue |
R202 |
T299 |
T297 |
prep |
to,clue |
R203 |
T300 |
T301 |
poss |
its,function |
R204 |
T301 |
T299 |
pobj |
function,to |
R205 |
T302 |
T286 |
punct |
", ",offers |
R206 |
T303 |
T304 |
mark |
although,are |
R207 |
T304 |
T286 |
advcl |
are,offers |
R208 |
T305 |
T304 |
expl |
there,are |
R209 |
T306 |
T307 |
nummod |
eight,segments |
R210 |
T307 |
T304 |
attr |
segments,are |
R211 |
T308 |
T307 |
amod |
repeated,segments |
R212 |
T309 |
T310 |
punct |
(,termed |
R213 |
T310 |
T307 |
parataxis |
termed,segments |
R214 |
T311 |
T312 |
compound |
BRC,repeats |
R215 |
T312 |
T310 |
oprd |
repeats,termed |
R216 |
T313 |
T310 |
punct |
),termed |
R217 |
T314 |
T307 |
prep |
in,segments |
R218 |
T315 |
T316 |
det |
the,middle |
R219 |
T316 |
T314 |
pobj |
middle,in |
R220 |
T317 |
T316 |
prep |
of,middle |
R221 |
T318 |
T319 |
det |
the,protein |
R222 |
T319 |
T317 |
pobj |
protein,of |
R223 |
T320 |
T321 |
dep |
that,are |
R224 |
T321 |
T307 |
relcl |
are,segments |
R225 |
T322 |
T323 |
advmod |
highly,conserved |
R226 |
T323 |
T321 |
acomp |
conserved,are |
R227 |
T324 |
T321 |
prep |
among,are |
R228 |
T325 |
T326 |
amod |
mammalian,orthologs |
R229 |
T326 |
T324 |
pobj |
orthologs,among |
R230 |
T327 |
T328 |
punct |
[,8 |
R231 |
T328 |
T304 |
parataxis |
8,are |
R232 |
T329 |
T328 |
nummod |
7,8 |
R233 |
T330 |
T328 |
punct |
",",8 |
R234 |
T331 |
T328 |
punct |
],8 |
R235 |
T332 |
T286 |
punct |
.,offers |