Id |
Subject |
Object |
Predicate |
Lexical cue |
T43 |
0-3 |
CD |
denotes |
Two |
T42 |
0-121 |
sentence |
denotes |
Two recent papers provide new evidence relevant to the role of the breast cancer susceptibility gene BRCA2 in DNA repair. |
T45 |
4-10 |
JJ |
denotes |
recent |
T44 |
11-17 |
NNS |
denotes |
papers |
T46 |
18-25 |
VBP |
denotes |
provide |
T47 |
26-29 |
JJ |
denotes |
new |
T48 |
30-38 |
NN |
denotes |
evidence |
T49 |
39-47 |
JJ |
denotes |
relevant |
T50 |
48-50 |
IN |
denotes |
to |
T51 |
51-54 |
DT |
denotes |
the |
T52 |
55-59 |
NN |
denotes |
role |
T53 |
60-62 |
IN |
denotes |
of |
T54 |
63-66 |
DT |
denotes |
the |
T56 |
67-73 |
NN |
denotes |
breast |
T57 |
74-80 |
NN |
denotes |
cancer |
T58 |
81-95 |
NN |
denotes |
susceptibility |
T55 |
96-100 |
NN |
denotes |
gene |
T59 |
101-106 |
NN |
denotes |
BRCA2 |
T60 |
107-109 |
IN |
denotes |
in |
T61 |
110-113 |
NN |
denotes |
DNA |
T62 |
114-120 |
NN |
denotes |
repair |
T63 |
120-121 |
. |
denotes |
. |
T64 |
121-268 |
sentence |
denotes |
Moynahan et al provide genetic data indicating a requirement for BRCA2 in homology-dependent (recombinational) repair of DNA double-strand breaks. |
T65 |
122-130 |
NNP |
denotes |
Moynahan |
T67 |
131-133 |
FW |
denotes |
et |
T68 |
134-136 |
FW |
denotes |
al |
T66 |
137-144 |
VBP |
denotes |
provide |
T69 |
145-152 |
JJ |
denotes |
genetic |
T70 |
153-157 |
NNS |
denotes |
data |
T71 |
158-168 |
VBG |
denotes |
indicating |
T72 |
169-170 |
DT |
denotes |
a |
T73 |
171-182 |
NN |
denotes |
requirement |
T74 |
183-186 |
IN |
denotes |
for |
T75 |
187-192 |
NN |
denotes |
BRCA2 |
T76 |
193-195 |
IN |
denotes |
in |
T77 |
196-204 |
JJ |
denotes |
homology |
T79 |
204-205 |
HYPH |
denotes |
- |
T78 |
205-214 |
JJ |
denotes |
dependent |
T81 |
215-216 |
-LRB- |
denotes |
( |
T80 |
216-231 |
JJ |
denotes |
recombinational |
T83 |
231-232 |
-RRB- |
denotes |
) |
T82 |
233-239 |
NN |
denotes |
repair |
T84 |
240-242 |
IN |
denotes |
of |
T85 |
243-246 |
NN |
denotes |
DNA |
T87 |
247-253 |
JJ |
denotes |
double |
T89 |
253-254 |
HYPH |
denotes |
- |
T88 |
254-260 |
NN |
denotes |
strand |
T86 |
261-267 |
NNS |
denotes |
breaks |
T90 |
267-268 |
. |
denotes |
. |
T91 |
268-405 |
sentence |
denotes |
The second paper, by Davies et al, begins to address the mechanism through which BRCA2 makes its contribution to recombinational repair. |
T92 |
269-272 |
DT |
denotes |
The |
T94 |
273-279 |
JJ |
denotes |
second |
T93 |
280-285 |
NN |
denotes |
paper |
T96 |
285-287 |
, |
denotes |
, |
T97 |
287-289 |
IN |
denotes |
by |
T98 |
290-296 |
NNP |
denotes |
Davies |
T99 |
297-299 |
FW |
denotes |
et |
T100 |
300-302 |
FW |
denotes |
al |
T101 |
302-304 |
, |
denotes |
, |
T95 |
304-310 |
VBZ |
denotes |
begins |
T102 |
311-313 |
TO |
denotes |
to |
T103 |
314-321 |
VB |
denotes |
address |
T104 |
322-325 |
DT |
denotes |
the |
T105 |
326-335 |
NN |
denotes |
mechanism |
T106 |
336-343 |
IN |
denotes |
through |
T108 |
344-349 |
WDT |
denotes |
which |
T109 |
350-355 |
NN |
denotes |
BRCA2 |
T107 |
356-361 |
VBZ |
denotes |
makes |
T110 |
362-365 |
PRP$ |
denotes |
its |
T111 |
366-378 |
NN |
denotes |
contribution |
T112 |
379-381 |
IN |
denotes |
to |
T113 |
382-397 |
JJ |
denotes |
recombinational |
T114 |
398-404 |
NN |
denotes |
repair |
T115 |
404-405 |
. |
denotes |
. |
T116 |
405-518 |
sentence |
denotes |
BRCA2 appears to function in recombination via interactions with the major eukaryotic recombinase RAD51 [1,2,3]. |
T117 |
406-411 |
NN |
denotes |
BRCA2 |
T118 |
412-419 |
VBZ |
denotes |
appears |
T119 |
420-422 |
TO |
denotes |
to |
T120 |
423-431 |
VB |
denotes |
function |
T121 |
432-434 |
IN |
denotes |
in |
T122 |
435-448 |
NN |
denotes |
recombination |
T123 |
449-452 |
IN |
denotes |
via |
T124 |
453-465 |
NNS |
denotes |
interactions |
T125 |
466-470 |
IN |
denotes |
with |
T126 |
471-474 |
DT |
denotes |
the |
T128 |
475-480 |
JJ |
denotes |
major |
T129 |
481-491 |
JJ |
denotes |
eukaryotic |
T127 |
492-503 |
NN |
denotes |
recombinase |
T130 |
504-509 |
NN |
denotes |
RAD51 |
T131 |
510-511 |
-LRB- |
denotes |
[ |
T133 |
511-512 |
CD |
denotes |
1 |
T134 |
512-513 |
, |
denotes |
, |
T135 |
513-514 |
CD |
denotes |
2 |
T136 |
514-515 |
, |
denotes |
, |
T132 |
515-516 |
CD |
denotes |
3 |
T137 |
516-517 |
-RRB- |
denotes |
] |
T138 |
517-518 |
. |
denotes |
. |
T139 |
518-718 |
sentence |
denotes |
We briefly review the context in which the two studies were carried out, we comment on the results presented, and we discuss models designed to account for the role of BRCA2 in RAD51–mediated repair. |
T140 |
519-521 |
PRP |
denotes |
We |
T142 |
522-529 |
RB |
denotes |
briefly |
T141 |
530-536 |
VBP |
denotes |
review |
T143 |
537-540 |
DT |
denotes |
the |
T144 |
541-548 |
NN |
denotes |
context |
T145 |
549-551 |
IN |
denotes |
in |
T147 |
552-557 |
WDT |
denotes |
which |
T148 |
558-561 |
DT |
denotes |
the |
T150 |
562-565 |
CD |
denotes |
two |
T149 |
566-573 |
NNS |
denotes |
studies |
T151 |
574-578 |
VBD |
denotes |
were |
T146 |
579-586 |
VBN |
denotes |
carried |
T152 |
587-590 |
RP |
denotes |
out |
T153 |
590-592 |
, |
denotes |
, |
T154 |
592-594 |
PRP |
denotes |
we |
T155 |
595-602 |
VBP |
denotes |
comment |
T156 |
603-605 |
IN |
denotes |
on |
T157 |
606-609 |
DT |
denotes |
the |
T158 |
610-617 |
NNS |
denotes |
results |
T159 |
618-627 |
VBN |
denotes |
presented |
T160 |
627-629 |
, |
denotes |
, |
T161 |
629-632 |
CC |
denotes |
and |
T162 |
633-635 |
PRP |
denotes |
we |
T163 |
636-643 |
VBP |
denotes |
discuss |
T164 |
644-650 |
NNS |
denotes |
models |
T165 |
651-659 |
VBN |
denotes |
designed |
T166 |
660-662 |
TO |
denotes |
to |
T167 |
663-670 |
VB |
denotes |
account |
T168 |
671-674 |
IN |
denotes |
for |
T169 |
675-678 |
DT |
denotes |
the |
T170 |
679-683 |
NN |
denotes |
role |
T171 |
684-686 |
IN |
denotes |
of |
T172 |
687-692 |
NN |
denotes |
BRCA2 |
T173 |
693-695 |
IN |
denotes |
in |
T174 |
696-701 |
NN |
denotes |
RAD51 |
T176 |
701-702 |
HYPH |
denotes |
– |
T175 |
702-710 |
VBN |
denotes |
mediated |
T177 |
711-717 |
NN |
denotes |
repair |
T178 |
717-718 |
. |
denotes |
. |
R10 |
T48 |
T46 |
dobj |
evidence,provide |
R100 |
T146 |
T144 |
relcl |
carried,context |
R101 |
T147 |
T145 |
pobj |
which,in |
R102 |
T148 |
T149 |
det |
the,studies |
R103 |
T149 |
T146 |
nsubjpass |
studies,carried |
R104 |
T150 |
T149 |
nummod |
two,studies |
R105 |
T151 |
T146 |
auxpass |
were,carried |
R106 |
T152 |
T146 |
prt |
out,carried |
R107 |
T153 |
T141 |
punct |
", ",review |
R108 |
T154 |
T155 |
nsubj |
we,comment |
R109 |
T155 |
T141 |
conj |
comment,review |
R11 |
T49 |
T48 |
amod |
relevant,evidence |
R110 |
T156 |
T155 |
prep |
on,comment |
R111 |
T157 |
T158 |
det |
the,results |
R112 |
T158 |
T156 |
pobj |
results,on |
R113 |
T159 |
T158 |
acl |
presented,results |
R114 |
T160 |
T155 |
punct |
", ",comment |
R115 |
T161 |
T155 |
cc |
and,comment |
R116 |
T162 |
T163 |
nsubj |
we,discuss |
R117 |
T163 |
T155 |
conj |
discuss,comment |
R118 |
T164 |
T163 |
dobj |
models,discuss |
R119 |
T165 |
T164 |
acl |
designed,models |
R12 |
T50 |
T49 |
prep |
to,relevant |
R120 |
T166 |
T167 |
aux |
to,account |
R121 |
T167 |
T165 |
advcl |
account,designed |
R122 |
T168 |
T167 |
prep |
for,account |
R123 |
T169 |
T170 |
det |
the,role |
R124 |
T170 |
T168 |
pobj |
role,for |
R125 |
T171 |
T170 |
prep |
of,role |
R126 |
T172 |
T171 |
pobj |
BRCA2,of |
R127 |
T173 |
T170 |
prep |
in,role |
R128 |
T174 |
T175 |
npadvmod |
RAD51,mediated |
R129 |
T175 |
T177 |
amod |
mediated,repair |
R13 |
T51 |
T52 |
det |
the,role |
R130 |
T176 |
T175 |
punct |
–,mediated |
R131 |
T177 |
T173 |
pobj |
repair,in |
R132 |
T178 |
T163 |
punct |
.,discuss |
R14 |
T52 |
T50 |
pobj |
role,to |
R15 |
T53 |
T52 |
prep |
of,role |
R16 |
T54 |
T55 |
det |
the,gene |
R17 |
T55 |
T53 |
pobj |
gene,of |
R18 |
T56 |
T57 |
compound |
breast,cancer |
R19 |
T57 |
T58 |
compound |
cancer,susceptibility |
R20 |
T58 |
T55 |
compound |
susceptibility,gene |
R21 |
T59 |
T55 |
appos |
BRCA2,gene |
R22 |
T60 |
T52 |
prep |
in,role |
R23 |
T61 |
T62 |
compound |
DNA,repair |
R24 |
T62 |
T60 |
pobj |
repair,in |
R25 |
T63 |
T46 |
punct |
.,provide |
R26 |
T65 |
T66 |
nsubj |
Moynahan,provide |
R27 |
T67 |
T68 |
advmod |
et,al |
R28 |
T68 |
T65 |
advmod |
al,Moynahan |
R29 |
T69 |
T70 |
amod |
genetic,data |
R30 |
T70 |
T66 |
dobj |
data,provide |
R31 |
T71 |
T70 |
acl |
indicating,data |
R32 |
T72 |
T73 |
det |
a,requirement |
R33 |
T73 |
T71 |
dobj |
requirement,indicating |
R34 |
T74 |
T73 |
prep |
for,requirement |
R35 |
T75 |
T74 |
pobj |
BRCA2,for |
R36 |
T76 |
T73 |
prep |
in,requirement |
R37 |
T77 |
T78 |
amod |
homology,dependent |
R38 |
T78 |
T80 |
amod |
dependent,recombinational |
R39 |
T79 |
T78 |
punct |
-,dependent |
R40 |
T80 |
T82 |
amod |
recombinational,repair |
R41 |
T81 |
T80 |
punct |
(,recombinational |
R42 |
T82 |
T76 |
pobj |
repair,in |
R43 |
T83 |
T82 |
punct |
),repair |
R44 |
T84 |
T82 |
prep |
of,repair |
R45 |
T85 |
T86 |
nmod |
DNA,breaks |
R46 |
T86 |
T84 |
pobj |
breaks,of |
R47 |
T87 |
T88 |
amod |
double,strand |
R48 |
T88 |
T86 |
compound |
strand,breaks |
R49 |
T89 |
T88 |
punct |
-,strand |
R50 |
T90 |
T66 |
punct |
.,provide |
R51 |
T92 |
T93 |
det |
The,paper |
R52 |
T93 |
T95 |
nsubj |
paper,begins |
R53 |
T94 |
T93 |
amod |
second,paper |
R54 |
T96 |
T93 |
punct |
", ",paper |
R55 |
T97 |
T93 |
prep |
by,paper |
R56 |
T98 |
T97 |
pobj |
Davies,by |
R57 |
T99 |
T100 |
advmod |
et,al |
R58 |
T100 |
T98 |
advmod |
al,Davies |
R59 |
T101 |
T95 |
punct |
", ",begins |
R6 |
T43 |
T44 |
nummod |
Two,papers |
R60 |
T102 |
T103 |
aux |
to,address |
R61 |
T103 |
T95 |
xcomp |
address,begins |
R62 |
T104 |
T105 |
det |
the,mechanism |
R63 |
T105 |
T103 |
dobj |
mechanism,address |
R64 |
T106 |
T107 |
prep |
through,makes |
R65 |
T107 |
T105 |
relcl |
makes,mechanism |
R66 |
T108 |
T106 |
pobj |
which,through |
R67 |
T109 |
T107 |
nsubj |
BRCA2,makes |
R68 |
T110 |
T111 |
poss |
its,contribution |
R69 |
T111 |
T107 |
dobj |
contribution,makes |
R7 |
T44 |
T46 |
nsubj |
papers,provide |
R70 |
T112 |
T111 |
prep |
to,contribution |
R71 |
T113 |
T114 |
amod |
recombinational,repair |
R72 |
T114 |
T112 |
pobj |
repair,to |
R73 |
T115 |
T95 |
punct |
.,begins |
R74 |
T117 |
T118 |
nsubj |
BRCA2,appears |
R75 |
T119 |
T120 |
aux |
to,function |
R76 |
T120 |
T118 |
xcomp |
function,appears |
R77 |
T121 |
T120 |
prep |
in,function |
R78 |
T122 |
T121 |
pobj |
recombination,in |
R79 |
T123 |
T120 |
prep |
via,function |
R8 |
T45 |
T44 |
amod |
recent,papers |
R80 |
T124 |
T123 |
pobj |
interactions,via |
R81 |
T125 |
T124 |
prep |
with,interactions |
R82 |
T126 |
T127 |
det |
the,recombinase |
R83 |
T127 |
T125 |
pobj |
recombinase,with |
R84 |
T128 |
T127 |
amod |
major,recombinase |
R85 |
T129 |
T127 |
amod |
eukaryotic,recombinase |
R86 |
T130 |
T127 |
appos |
RAD51,recombinase |
R87 |
T131 |
T132 |
punct |
[,3 |
R88 |
T132 |
T118 |
parataxis |
3,appears |
R89 |
T133 |
T132 |
nummod |
1,3 |
R9 |
T47 |
T48 |
amod |
new,evidence |
R90 |
T134 |
T132 |
punct |
",",3 |
R91 |
T135 |
T132 |
nummod |
2,3 |
R92 |
T136 |
T132 |
punct |
",",3 |
R93 |
T137 |
T132 |
punct |
],3 |
R94 |
T138 |
T118 |
punct |
.,appears |
R95 |
T140 |
T141 |
nsubj |
We,review |
R96 |
T142 |
T141 |
advmod |
briefly,review |
R97 |
T143 |
T144 |
det |
the,context |
R98 |
T144 |
T141 |
dobj |
context,review |
R99 |
T145 |
T146 |
prep |
in,carried |