PMC:138691 / 12286-13041 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T2862 0-3 RB denotes Yet
T2864 4-11 DT denotes another
T2865 12-21 JJ denotes potential
T2863 22-26 NN denotes role
T2867 27-30 IN denotes for
T2868 31-36 NN denotes BRCA2
T2869 37-39 IN denotes in
T2870 40-49 VBG denotes promoting
T2871 50-55 NN denotes RAD51
T2873 55-56 HYPH denotes -
T2872 56-65 JJ denotes dependent
T2875 66-81 JJ denotes recombinational
T2874 82-88 NN denotes repair
T2866 89-91 VBZ denotes is
T2876 92-93 DT denotes a
T2878 94-102 JJ denotes positive
T2877 103-107 NN denotes role
T2879 108-110 IN denotes in
T2880 111-119 NN denotes assembly
T2881 120-122 IN denotes of
T2882 123-128 NN denotes RAD51
T2883 129-131 IN denotes at
T2884 132-139 VBN denotes damaged
T2885 140-145 NNS denotes sites
T2886 146-147 -LRB- denotes (
T2888 147-151 NN denotes Fig.
T2887 152-154 NN denotes 2b
T2889 154-155 -RRB- denotes )
T2890 155-156 . denotes .
T2891 156-284 sentence denotes Several proteins that interact with RAD51 are thought to 'mediate' assembly of RAD51 at sites of DNA damage (reviewed in [30]).
T2892 157-164 JJ denotes Several
T2893 165-173 NN denotes proteins
T2895 174-178 WDT denotes that
T2896 179-187 VBP denotes interact
T2897 188-192 IN denotes with
T2898 193-198 NN denotes RAD51
T2899 199-202 VBP denotes are
T2894 203-210 VBN denotes thought
T2900 211-213 TO denotes to
T2902 214-215 `` denotes '
T2901 215-222 VB denotes mediate
T2903 222-223 '' denotes '
T2904 224-232 NN denotes assembly
T2905 233-235 IN denotes of
T2906 236-241 NN denotes RAD51
T2907 242-244 IN denotes at
T2908 245-250 NNS denotes sites
T2909 251-253 IN denotes of
T2910 254-257 NN denotes DNA
T2911 258-264 NN denotes damage
T2912 265-266 -LRB- denotes (
T2913 266-274 VBN denotes reviewed
T2914 275-277 IN denotes in
T2915 278-279 -LRB- denotes [
T2916 279-281 CD denotes 30
T2917 281-282 -RRB- denotes ]
T2918 282-283 -RRB- denotes )
T2919 283-284 . denotes .
T2920 284-435 sentence denotes RAD51 paralogs in particular, including XRCC2, XRCC3, RAD51B, RAD51C and RAD51D, may function as a complex that actively promotes RAD51 assembly [31].
T2921 285-290 NN denotes RAD51
T2922 291-299 NNS denotes paralogs
T2924 300-302 IN denotes in
T2925 303-313 JJ denotes particular
T2926 313-315 , denotes ,
T2927 315-324 VBG denotes including
T2928 325-330 NN denotes XRCC2
T2929 330-332 , denotes ,
T2930 332-337 NN denotes XRCC3
T2931 337-339 , denotes ,
T2932 339-345 NN denotes RAD51B
T2933 345-347 , denotes ,
T2934 347-353 NN denotes RAD51C
T2935 354-357 CC denotes and
T2936 358-364 NN denotes RAD51D
T2937 364-366 , denotes ,
T2938 366-369 MD denotes may
T2923 370-378 VB denotes function
T2939 379-381 IN denotes as
T2940 382-383 DT denotes a
T2941 384-391 NN denotes complex
T2942 392-396 WDT denotes that
T2944 397-405 RB denotes actively
T2943 406-414 VBZ denotes promotes
T2945 415-420 NN denotes RAD51
T2946 421-429 NN denotes assembly
T2947 430-431 -LRB- denotes [
T2948 431-433 CD denotes 31
T2949 433-434 -RRB- denotes ]
T2950 434-435 . denotes .
T2951 435-555 sentence denotes BRCA2 could cooperate with RAD51 paralogs in promoting RAD51 assembly, or even provide an alternative assembly pathway.
T2952 436-441 NN denotes BRCA2
T2954 442-447 MD denotes could
T2953 448-457 VB denotes cooperate
T2955 458-462 IN denotes with
T2956 463-468 NN denotes RAD51
T2957 469-477 NNS denotes paralogs
T2958 478-480 IN denotes in
T2959 481-490 VBG denotes promoting
T2960 491-496 NN denotes RAD51
T2961 497-505 NN denotes assembly
T2962 505-507 , denotes ,
T2963 507-509 CC denotes or
T2964 510-514 RB denotes even
T2965 515-522 VB denotes provide
T2966 523-525 DT denotes an
T2968 526-537 JJ denotes alternative
T2969 538-546 NN denotes assembly
T2967 547-554 NN denotes pathway
T2970 554-555 . denotes .
T2971 555-755 sentence denotes The observation that BRCA2 localizes to damage-induced subnuclear foci with RAD51 seems consistent with the possibility that BRCA2 plays a positive role in assembly of the recombination complex [11].
T2972 556-559 DT denotes The
T2973 560-571 NN denotes observation
T2975 572-576 IN denotes that
T2977 577-582 NN denotes BRCA2
T2976 583-592 VBZ denotes localizes
T2978 593-595 IN denotes to
T2979 596-602 NN denotes damage
T2981 602-603 HYPH denotes -
T2980 603-610 VBN denotes induced
T2983 611-621 JJ denotes subnuclear
T2982 622-626 NNS denotes foci
T2984 627-631 IN denotes with
T2985 632-637 NN denotes RAD51
T2974 638-643 VBZ denotes seems
T2986 644-654 JJ denotes consistent
T2987 655-659 IN denotes with
T2988 660-663 DT denotes the
T2989 664-675 NN denotes possibility
T2990 676-680 IN denotes that
T2992 681-686 NN denotes BRCA2
T2991 687-692 VBZ denotes plays
T2993 693-694 DT denotes a
T2995 695-703 JJ denotes positive
T2994 704-708 NN denotes role
T2996 709-711 IN denotes in
T2997 712-720 NN denotes assembly
T2998 721-723 IN denotes of
T2999 724-727 DT denotes the
T3001 728-741 NN denotes recombination
T3000 742-749 NN denotes complex
T3002 750-751 -LRB- denotes [
T3003 751-753 CD denotes 11
T3004 753-754 -RRB- denotes ]
T3005 754-755 . denotes .
R1927 T2862 T2863 advmod Yet,role
R1929 T2864 T2863 det another,role
R1930 T2867 T2863 prep for,role
R1931 T2863 T2866 nsubj role,is
R1932 T2865 T2863 amod potential,role
R1933 T2869 T2863 prep in,role
R1934 T2870 T2869 pcomp promoting,in
R1935 T2868 T2867 pobj BRCA2,for
R1936 T2872 T2874 amod dependent,repair
R1937 T2873 T2872 punct -,dependent
R1938 T2871 T2872 npadvmod RAD51,dependent
R1939 T2875 T2874 amod recombinational,repair
R1940 T2876 T2877 det a,role
R1941 T2874 T2870 dobj repair,promoting
R1942 T2878 T2877 amod positive,role
R1943 T2877 T2866 attr role,is
R1944 T2880 T2879 pobj assembly,in
R1945 T2881 T2880 prep of,assembly
R1946 T2879 T2877 prep in,role
R1947 T2883 T2880 prep at,assembly
R1948 T2884 T2885 amod damaged,sites
R1949 T2882 T2881 pobj RAD51,of
R1950 T2886 T2887 punct (,2b
R1951 T2885 T2883 pobj sites,at
R1952 T2888 T2887 compound Fig.,2b
R1953 T2889 T2887 punct ),2b
R1954 T2887 T2866 parataxis 2b,is
R1955 T2892 T2893 amod Several,proteins
R1956 T2890 T2866 punct .,is
R1957 T2895 T2896 dep that,interact
R1958 T2893 T2894 nsubjpass proteins,thought
R1959 T2897 T2896 prep with,interact
R1960 T2898 T2897 pobj RAD51,with
R1961 T2896 T2893 relcl interact,proteins
R1962 T2900 T2901 aux to,mediate
R1963 T2901 T2894 xcomp mediate,thought
R1964 T2899 T2894 auxpass are,thought
R1965 T2903 T2901 punct ',mediate
R1966 T2904 T2901 dobj assembly,mediate
R1967 T2902 T2901 punct ',mediate
R1968 T2906 T2905 pobj RAD51,of
R1969 T2907 T2901 prep at,mediate
R1970 T2905 T2904 prep of,assembly
R1971 T2909 T2908 prep of,sites
R1972 T2910 T2911 compound DNA,damage
R1973 T2908 T2907 pobj sites,at
R1974 T2912 T2913 punct (,reviewed
R1975 T2913 T2894 parataxis reviewed,thought
R1976 T2911 T2909 pobj damage,of
R1977 T2914 T2913 prep in,reviewed
R1978 T2916 T2914 pobj 30,in
R1979 T2917 T2913 punct ],reviewed
R1980 T2915 T2914 punct [,in
R1981 T2919 T2894 punct .,thought
R1982 T2918 T2913 punct ),reviewed
R1983 T2921 T2922 compound RAD51,paralogs
R1984 T2924 T2922 prep in,paralogs
R1985 T2922 T2923 nsubj paralogs,function
R1986 T2926 T2922 punct ", ",paralogs
R1987 T2925 T2924 amod particular,in
R1988 T2928 T2927 pobj XRCC2,including
R1989 T2929 T2928 punct ", ",XRCC2
R1990 T2927 T2922 prep including,paralogs
R1991 T2931 T2930 punct ", ",XRCC3
R1992 T2932 T2930 conj RAD51B,XRCC3
R1993 T2930 T2928 conj XRCC3,XRCC2
R1994 T2934 T2932 conj RAD51C,RAD51B
R1995 T2935 T2934 cc and,RAD51C
R1996 T2933 T2932 punct ", ",RAD51B
R1997 T2937 T2923 punct ", ",function
R1998 T2938 T2923 aux may,function
R1999 T2936 T2934 conj RAD51D,RAD51C
R2000 T2940 T2941 det a,complex
R2001 T2941 T2939 pobj complex,as
R2002 T2939 T2923 prep as,function
R2003 T2943 T2941 relcl promotes,complex
R2004 T2944 T2943 advmod actively,promotes
R2005 T2942 T2943 dep that,promotes
R2006 T2946 T2943 dobj assembly,promotes
R2007 T2947 T2948 punct [,31
R2008 T2945 T2946 compound RAD51,assembly
R2009 T2949 T2948 punct ],31
R2010 T2950 T2923 punct .,function
R2011 T2948 T2923 parataxis 31,function
R2012 T2952 T2953 nsubj BRCA2,cooperate
R2013 T2954 T2953 aux could,cooperate
R2014 T2956 T2957 compound RAD51,paralogs
R2015 T2957 T2955 pobj paralogs,with
R2016 T2955 T2953 prep with,cooperate
R2017 T2959 T2958 pcomp promoting,in
R2018 T2960 T2961 compound RAD51,assembly
R2019 T2958 T2953 prep in,cooperate
R2020 T2962 T2953 punct ", ",cooperate
R2021 T2963 T2953 cc or,cooperate
R2022 T2961 T2959 dobj assembly,promoting
R2023 T2965 T2953 conj provide,cooperate
R2024 T2966 T2967 det an,pathway
R2025 T2964 T2965 advmod even,provide
R2026 T2968 T2967 amod alternative,pathway
R2027 T2969 T2967 compound assembly,pathway
R2028 T2967 T2965 dobj pathway,provide
R2029 T2972 T2973 det The,observation
R2030 T2970 T2953 punct .,cooperate
R2031 T2975 T2976 mark that,localizes
R2032 T2976 T2973 acl localizes,observation
R2033 T2973 T2974 nsubj observation,seems
R2034 T2978 T2976 prep to,localizes
R2035 T2979 T2980 npadvmod damage,induced
R2036 T2977 T2976 nsubj BRCA2,localizes
R2037 T2981 T2980 punct -,induced
R2038 T2980 T2982 amod induced,foci
R2039 T2983 T2982 amod subnuclear,foci
R2040 T2982 T2978 pobj foci,to
R2041 T2985 T2984 pobj RAD51,with
R2042 T2986 T2974 oprd consistent,seems
R2043 T2984 T2976 prep with,localizes
R2044 T2988 T2989 det the,possibility
R2045 T2987 T2986 prep with,consistent
R2046 T2990 T2991 mark that,plays
R2047 T2989 T2987 pobj possibility,with
R2048 T2992 T2991 nsubj BRCA2,plays
R2049 T2991 T2989 acl plays,possibility
R2050 T2994 T2991 dobj role,plays
R2051 T2995 T2994 amod positive,role
R2052 T2993 T2994 det a,role
R2053 T2997 T2996 pobj assembly,in
R2054 T2996 T2991 prep in,plays
R2055 T2999 T3000 det the,complex
R2056 T3000 T2998 pobj complex,of
R2057 T2998 T2997 prep of,assembly
R2058 T3002 T3003 punct [,11
R2059 T3001 T3000 compound recombination,complex
R2060 T3004 T3003 punct ],11
R2061 T3003 T2974 parataxis 11,seems
R2063 T3005 T2974 punct .,seems