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PMC:1064854 / 48755-49746 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T31447 0-2 PRP denotes We
T31448 3-8 VBD denotes found
T31449 9-13 IN denotes that
T31451 14-19 IN denotes after
T31452 20-22 CD denotes 18
T31453 23-25 NN denotes wk
T31454 26-28 IN denotes of
T31455 29-32 NN denotes age
T31456 32-34 , denotes ,
T31457 34-40 JJ denotes female
T31459 41-44 NN denotes PGC
T31461 44-45 HYPH denotes -
T31460 45-47 NN denotes 1α
T31462 47-48 SYM denotes −
T31463 48-49 HYPH denotes /
T31464 49-50 SYM denotes −
T31458 51-55 NNS denotes mice
T31450 56-63 VBP denotes exhibit
T31465 64-65 DT denotes a
T31467 66-70 JJ denotes mild
T31468 71-74 CC denotes but
T31469 75-88 RB denotes significantly
T31470 89-97 JJ denotes abnormal
T31471 98-104 NN denotes weight
T31466 105-113 NN denotes increase
T31472 114-124 VBN denotes associated
T31473 125-129 IN denotes with
T31474 130-139 VBN denotes increased
T31476 140-143 NN denotes fat
T31475 144-150 NNS denotes stores
T31477 150-151 . denotes .
T31478 151-204 sentence denotes Lean mass was unchanged at the time points examined.
T31479 152-156 JJ denotes Lean
T31480 157-161 NN denotes mass
T31481 162-165 VBD denotes was
T31482 166-175 JJ denotes unchanged
T31483 176-178 IN denotes at
T31484 179-182 DT denotes the
T31486 183-187 NN denotes time
T31485 188-194 NNS denotes points
T31487 195-203 VBN denotes examined
T31488 203-204 . denotes .
T31489 204-328 sentence denotes With further aging, a modest but significant increase in body fat was also noted in male PGC-1α−/− mice (unpublished data).
T31490 205-209 IN denotes With
T31492 210-217 JJ denotes further
T31493 218-223 NN denotes aging
T31494 223-225 , denotes ,
T31495 225-226 DT denotes a
T31497 227-233 JJ denotes modest
T31498 234-237 CC denotes but
T31499 238-249 JJ denotes significant
T31496 250-258 NN denotes increase
T31500 259-261 IN denotes in
T31501 262-266 NN denotes body
T31502 267-270 NN denotes fat
T31503 271-274 VBD denotes was
T31504 275-279 RB denotes also
T31491 280-285 VBN denotes noted
T31505 286-288 IN denotes in
T31506 289-293 JJ denotes male
T31508 294-297 NN denotes PGC
T31510 297-298 HYPH denotes -
T31509 298-300 NN denotes 1α
T31511 300-301 SYM denotes −
T31512 301-302 HYPH denotes /
T31513 302-303 SYM denotes −
T31507 304-308 NNS denotes mice
T31514 309-310 -LRB- denotes (
T31516 310-321 JJ denotes unpublished
T31515 322-326 NNS denotes data
T31517 326-327 -RRB- denotes )
T31518 327-328 . denotes .
T31519 328-399 sentence denotes The basis for the observed abnormalities in weight control is unknown.
T31520 329-332 DT denotes The
T31521 333-338 NN denotes basis
T31523 339-342 IN denotes for
T31524 343-346 DT denotes the
T31526 347-355 VBN denotes observed
T31525 356-369 NNS denotes abnormalities
T31527 370-372 IN denotes in
T31528 373-379 NN denotes weight
T31529 380-387 NN denotes control
T31522 388-390 VBZ denotes is
T31530 391-398 JJ denotes unknown
T31531 398-399 . denotes .
T31532 399-487 sentence denotes We did not find differences in food intake or activity levels in female PGC-1α−/− mice.
T31533 400-402 PRP denotes We
T31535 403-406 VBD denotes did
T31536 407-410 RB denotes not
T31534 411-415 VB denotes find
T31537 416-427 NNS denotes differences
T31538 428-430 IN denotes in
T31539 431-435 NN denotes food
T31540 436-442 NN denotes intake
T31541 443-445 CC denotes or
T31542 446-454 NN denotes activity
T31543 455-461 NNS denotes levels
T31544 462-464 IN denotes in
T31545 465-471 JJ denotes female
T31547 472-475 NN denotes PGC
T31549 475-476 HYPH denotes -
T31548 476-478 NN denotes 1α
T31550 478-479 SYM denotes −
T31551 479-480 HYPH denotes /
T31552 480-481 SYM denotes −
T31546 482-486 NNS denotes mice
T31553 486-487 . denotes .
T31554 487-660 sentence denotes It is possible that a reduction in systemic energy utilization, related to the mitochondrial dysfunction, leads to increased fat mass and weight gain in the PGC-1α−/− mice.
T31555 488-490 PRP denotes It
T31556 491-493 VBZ denotes is
T31557 494-502 JJ denotes possible
T31558 503-507 IN denotes that
T31560 508-509 DT denotes a
T31561 510-519 NN denotes reduction
T31562 520-522 IN denotes in
T31563 523-531 JJ denotes systemic
T31565 532-538 NN denotes energy
T31564 539-550 NN denotes utilization
T31566 550-552 , denotes ,
T31567 552-559 VBN denotes related
T31568 560-562 IN denotes to
T31569 563-566 DT denotes the
T31571 567-580 JJ denotes mitochondrial
T31570 581-592 NN denotes dysfunction
T31572 592-594 , denotes ,
T31559 594-599 VBZ denotes leads
T31573 600-602 IN denotes to
T31574 603-612 VBN denotes increased
T31576 613-616 NN denotes fat
T31575 617-621 NN denotes mass
T31577 622-625 CC denotes and
T31578 626-632 NN denotes weight
T31579 633-637 NN denotes gain
T31580 638-640 IN denotes in
T31581 641-644 DT denotes the
T31583 645-648 NN denotes PGC
T31585 648-649 HYPH denotes -
T31584 649-651 NN denotes 1α
T31586 651-652 SYM denotes −
T31587 652-653 HYPH denotes /
T31588 653-654 SYM denotes −
T31582 655-659 NNS denotes mice
T31589 659-660 . denotes .
T31590 660-779 sentence denotes Interestingly, an association between PGC-1α gene polymorphisms and obesity in humans has been recently reported [26].
T31591 661-674 RB denotes Interestingly
T31593 674-676 , denotes ,
T31594 676-678 DT denotes an
T31595 679-690 NN denotes association
T31596 691-698 IN denotes between
T31597 699-702 NN denotes PGC
T31599 702-703 HYPH denotes -
T31598 703-705 NN denotes 1α
T31601 706-710 NN denotes gene
T31600 711-724 NNS denotes polymorphisms
T31602 725-728 CC denotes and
T31603 729-736 NN denotes obesity
T31604 737-739 IN denotes in
T31605 740-746 NNS denotes humans
T31606 747-750 VBZ denotes has
T31607 751-755 VBN denotes been
T31608 756-764 RB denotes recently
T31592 765-773 VBN denotes reported
T31609 774-775 -LRB- denotes [
T31610 775-777 CD denotes 26
T31611 777-778 -RRB- denotes ]
T31612 778-779 . denotes .
T31613 779-991 sentence denotes Clearly, future studies of male and female PGC-1α−/− mice in pure-strain backgrounds over a range of ages will be necessary to fully investigate the observed abnormalities in weight control and fat distribution.
T31614 780-787 RB denotes Clearly
T31616 787-789 , denotes ,
T31617 789-795 JJ denotes future
T31618 796-803 NNS denotes studies
T31619 804-806 IN denotes of
T31620 807-811 JJ denotes male
T31622 812-815 CC denotes and
T31623 816-822 JJ denotes female
T31624 823-826 NN denotes PGC
T31626 826-827 HYPH denotes -
T31625 827-829 NN denotes 1α
T31627 829-830 SYM denotes −
T31628 830-831 HYPH denotes /
T31629 831-832 SYM denotes −
T31621 833-837 NNS denotes mice
T31630 838-840 IN denotes in
T31631 841-845 JJ denotes pure
T31633 845-846 HYPH denotes -
T31632 846-852 NN denotes strain
T31634 853-864 NNS denotes backgrounds
T31635 865-869 IN denotes over
T31636 870-871 DT denotes a
T31637 872-877 NN denotes range
T31638 878-880 IN denotes of
T31639 881-885 NNS denotes ages
T31640 886-890 MD denotes will
T31615 891-893 VB denotes be
T31641 894-903 JJ denotes necessary
T31642 904-906 TO denotes to
T31644 907-912 RB denotes fully
T31643 913-924 VB denotes investigate
T31645 925-928 DT denotes the
T31647 929-937 VBN denotes observed
T31646 938-951 NNS denotes abnormalities
T31648 952-954 IN denotes in
T31649 955-961 NN denotes weight
T31650 962-969 NN denotes control
T31651 970-973 CC denotes and
T31652 974-977 NN denotes fat
T31653 978-990 NN denotes distribution
T31654 990-991 . denotes .
R6995 T31447 T31448 nsubj We,found
R6997 T31449 T31450 mark that,exhibit
R7000 T31450 T31448 ccomp exhibit,found
R7001 T31451 T31450 prep after,exhibit
R7002 T31452 T31453 nummod 18,wk
R7004 T31453 T31451 pobj wk,after
R7005 T31454 T31453 prep of,wk
R7006 T31455 T31454 pobj age,of
R7008 T31456 T31450 punct ", ",exhibit
R7009 T31457 T31458 amod female,mice
R7010 T31458 T31450 nsubj mice,exhibit
R7011 T31459 T31460 nmod PGC,1α
R7012 T31460 T31458 nmod 1α,mice
R7014 T31461 T31460 punct -,1α
R7015 T31462 T31460 punct −,1α
R7016 T31463 T31460 punct /,1α
R7017 T31464 T31460 punct −,1α
R7019 T31465 T31466 det a,increase
R7021 T31466 T31450 dobj increase,exhibit
R7022 T31467 T31466 amod mild,increase
R7023 T31468 T31467 cc but,mild
R7025 T31469 T31470 advmod significantly,abnormal
R7026 T31470 T31467 conj abnormal,mild
R7027 T31471 T31466 compound weight,increase
R7029 T31472 T31466 acl associated,increase
R7030 T31473 T31472 prep with,associated
R7031 T31474 T31475 amod increased,stores
R7033 T31475 T31473 pobj stores,with
R7034 T31476 T31475 compound fat,stores
R7036 T31477 T31448 punct .,found
R7037 T31479 T31480 amod Lean,mass
R7039 T31480 T31481 nsubj mass,was
R7041 T31482 T31481 acomp unchanged,was
R7042 T31483 T31481 prep at,was
R7043 T31484 T31485 det the,points
R7045 T31485 T31483 pobj points,at
R7046 T31486 T31485 compound time,points
R7047 T31487 T31485 acl examined,points
R7049 T31488 T31481 punct .,was
R7050 T31490 T31491 prep With,noted
R7052 T31492 T31493 amod further,aging
R7054 T31493 T31490 pobj aging,With
R7055 T31494 T31491 punct ", ",noted
R7056 T31495 T31496 det a,increase
R7057 T31496 T31491 nsubjpass increase,noted
R7059 T31497 T31496 amod modest,increase
R7060 T31498 T31497 cc but,modest
R7061 T31499 T31497 conj significant,modest
R7063 T31500 T31496 prep in,increase
R7064 T31501 T31502 compound body,fat
R7065 T31502 T31500 pobj fat,in
R7066 T31503 T31491 auxpass was,noted
R7067 T31504 T31491 advmod also,noted
R7068 T31505 T31491 prep in,noted
R7070 T31506 T31507 amod male,mice
R7071 T31507 T31505 pobj mice,in
R7072 T31508 T31509 nmod PGC,1α
R7074 T31509 T31507 nmod 1α,mice
R7075 T31510 T31509 punct -,1α
R7077 T31511 T31509 punct −,1α
R7078 T31512 T31509 punct /,1α
R7079 T31513 T31509 punct −,1α
R7081 T31514 T31515 punct (,data
R7082 T31515 T31491 parataxis data,noted
R7083 T31516 T31515 amod unpublished,data
R7085 T31517 T31515 punct ),data
R7086 T31518 T31491 punct .,noted
R7088 T31520 T31521 det The,basis
R7089 T31521 T31522 nsubj basis,is
R7091 T31523 T31521 prep for,basis
R7092 T31524 T31525 det the,abnormalities
R7093 T31525 T31523 pobj abnormalities,for
R7094 T31526 T31525 amod observed,abnormalities
R7096 T31527 T31525 prep in,abnormalities
R7097 T31528 T31529 compound weight,control
R7098 T31529 T31527 pobj control,in
R7100 T31530 T31522 acomp unknown,is
R7101 T31531 T31522 punct .,is
R7103 T31533 T31534 nsubj We,find
R7105 T31535 T31534 aux did,find
R7106 T31536 T31534 neg not,find
R7107 T31537 T31534 dobj differences,find
R7109 T31538 T31537 prep in,differences
R7110 T31539 T31540 compound food,intake
R7111 T31540 T31538 pobj intake,in
R7113 T31541 T31540 cc or,intake
R7114 T31542 T31543 compound activity,levels
R7115 T31543 T31540 conj levels,intake
R7116 T31544 T31534 prep in,find
R7120 T31545 T31546 amod female,mice
R7121 T31651 T31650 cc and,control
R7122 T31546 T31544 pobj mice,in
R7123 T31547 T31548 nmod PGC,1α
R7124 T31652 T31653 compound fat,distribution
R7125 T31548 T31546 nmod 1α,mice
R7126 T31549 T31548 punct -,1α
R7127 T31550 T31548 punct −,1α
R7128 T31653 T31650 conj distribution,control
R7129 T31551 T31548 punct /,1α
R7130 T31552 T31548 punct −,1α
R7131 T31654 T31615 punct .,be
R7132 T31553 T31534 punct .,find
R7133 T31555 T31556 nsubj It,is
R7135 T31557 T31556 acomp possible,is
R7136 T31558 T31559 mark that,leads
R7138 T31559 T31556 ccomp leads,is
R7139 T31560 T31561 det a,reduction
R7140 T31561 T31559 nsubj reduction,leads
R7142 T31562 T31561 prep in,reduction
R7143 T31563 T31564 amod systemic,utilization
R7144 T31564 T31562 pobj utilization,in
R7146 T31565 T31564 compound energy,utilization
R7149 T31566 T31561 punct ", ",reduction
R7150 T31567 T31561 acl related,reduction
R7152 T31568 T31567 prep to,related
R7153 T31569 T31570 det the,dysfunction
R7155 T31570 T31568 pobj dysfunction,to
R7156 T31571 T31570 amod mitochondrial,dysfunction
R7157 T31572 T31559 punct ", ",leads
R7159 T31573 T31559 prep to,leads
R7160 T31574 T31575 amod increased,mass
R7161 T31575 T31573 pobj mass,to
R7163 T31576 T31575 compound fat,mass
R7164 T31577 T31575 cc and,mass
R7166 T31578 T31579 compound weight,gain
R7167 T31579 T31575 conj gain,mass
R7168 T31580 T31559 prep in,leads
R7169 T31581 T31582 det the,mice
R7170 T31582 T31580 pobj mice,in
R7171 T31583 T31584 nmod PGC,1α
R7173 T31584 T31582 nmod 1α,mice
R7174 T31585 T31584 punct -,1α
R7175 T31586 T31584 punct −,1α
R7177 T31587 T31584 punct /,1α
R7178 T31588 T31584 punct −,1α
R7180 T31589 T31556 punct .,is
R7181 T31591 T31592 advmod Interestingly,reported
R7183 T31593 T31592 punct ", ",reported
R7185 T31594 T31595 det an,association
R7186 T31595 T31592 nsubjpass association,reported
R7187 T31596 T31595 prep between,association
R7189 T31597 T31598 compound PGC,1α
R7190 T31598 T31600 compound 1α,polymorphisms
R7191 T31599 T31598 punct -,1α
R7193 T31600 T31596 pobj polymorphisms,between
R7194 T31601 T31600 compound gene,polymorphisms
R7196 T31602 T31600 cc and,polymorphisms
R7197 T31603 T31600 conj obesity,polymorphisms
R7198 T31604 T31595 prep in,association
R7200 T31605 T31604 pobj humans,in
R7201 T31606 T31592 aux has,reported
R7202 T31607 T31592 auxpass been,reported
R7204 T31608 T31592 advmod recently,reported
R7205 T31609 T31610 punct [,26
R7206 T31610 T31592 parataxis 26,reported
R7208 T31611 T31610 punct ],26
R7209 T31612 T31592 punct .,reported
R7211 T31614 T31615 advmod Clearly,be
R7213 T31616 T31615 punct ", ",be
R7214 T31617 T31618 amod future,studies
R7215 T31618 T31615 nsubj studies,be
R7217 T31619 T31618 prep of,studies
R7218 T31620 T31621 amod male,mice
R7219 T31621 T31619 pobj mice,of
R7220 T31622 T31620 cc and,male
R7221 T31623 T31620 conj female,male
R7222 T31624 T31625 nmod PGC,1α
R7224 T31625 T31621 nmod 1α,mice
R7225 T31626 T31625 punct -,1α
R7226 T31627 T31625 punct −,1α
R7228 T31628 T31625 punct /,1α
R7229 T31629 T31625 punct −,1α
R7231 T31630 T31621 prep in,mice
R7232 T31631 T31632 amod pure,strain
R7234 T31632 T31634 compound strain,backgrounds
R7236 T31633 T31632 punct -,strain
R7237 T31634 T31630 pobj backgrounds,in
R7238 T31635 T31621 prep over,mice
R7240 T31636 T31637 det a,range
R7241 T31637 T31635 pobj range,over
R7242 T31638 T31637 prep of,range
R7244 T31639 T31638 pobj ages,of
R7245 T31640 T31615 aux will,be
R7246 T31641 T31615 acomp necessary,be
R7248 T31642 T31643 aux to,investigate
R7249 T31643 T31615 advcl investigate,be
R7251 T31644 T31643 advmod fully,investigate
R7252 T31645 T31646 det the,abnormalities
R7254 T31646 T31643 dobj abnormalities,investigate
R7255 T31647 T31646 amod observed,abnormalities
R7256 T31648 T31646 prep in,abnormalities
R7258 T31649 T31650 compound weight,control
R7259 T31650 T31648 pobj control,in