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PMC:1064854 / 21597-23357 JSONTXT 6 Projects

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Id Subject Object Predicate Lexical cue
T12906 0-2 TO denotes To
T12908 3-10 RB denotes further
T12907 11-19 VB denotes evaluate
T12910 20-23 DT denotes the
T12912 24-32 JJ denotes skeletal
T12913 33-39 NN denotes muscle
T12911 40-49 NN denotes phenotype
T12914 49-51 , denotes ,
T12915 51-59 NN denotes exercise
T12916 60-68 NN denotes capacity
T12917 69-72 VBD denotes was
T12909 73-81 VBN denotes assessed
T12918 82-84 IN denotes in
T12919 85-88 DT denotes the
T12921 89-92 NN denotes PGC
T12923 92-93 HYPH denotes -
T12922 93-95 NN denotes 1α
T12924 95-96 SYM denotes −
T12925 96-97 HYPH denotes /
T12926 97-98 SYM denotes −
T12920 99-103 NNS denotes mice
T12927 103-104 . denotes .
T12928 104-220 sentence denotes To this end, the PGC-1α−/− mice were exercised on a motorized treadmill apparatus using a run-to-exhaustion format.
T12929 105-107 IN denotes To
T12931 108-112 DT denotes this
T12932 113-116 NN denotes end
T12933 116-118 , denotes ,
T12934 118-121 DT denotes the
T12936 122-125 NN denotes PGC
T12938 125-126 HYPH denotes -
T12937 126-128 NN denotes 1α
T12939 128-129 SYM denotes −
T12940 129-130 HYPH denotes /
T12941 130-131 SYM denotes −
T12935 132-136 NNS denotes mice
T12942 137-141 VBD denotes were
T12930 142-151 VBN denotes exercised
T12943 152-154 IN denotes on
T12944 155-156 DT denotes a
T12946 157-166 VBN denotes motorized
T12947 167-176 NN denotes treadmill
T12945 177-186 NN denotes apparatus
T12948 187-192 VBG denotes using
T12949 193-194 DT denotes a
T12951 195-198 VB denotes run
T12952 198-199 HYPH denotes -
T12953 199-201 IN denotes to
T12954 201-202 HYPH denotes -
T12955 202-212 NN denotes exhaustion
T12950 213-219 NN denotes format
T12956 219-220 . denotes .
T12957 220-397 sentence denotes PGC-1α−/− mice (6–8 mo of age) exhibited a markedly reduced capacity to sustain running exercise (PGC-1α−/− mice, 64 ± 6 s; age-matched PGC-1α+/+ mice, 586 ± 104 s; Figure 4B).
T12958 221-224 NN denotes PGC
T12960 224-225 HYPH denotes -
T12959 225-227 NN denotes 1α
T12962 227-228 SYM denotes −
T12963 228-229 HYPH denotes /
T12964 229-230 SYM denotes −
T12961 231-235 NNS denotes mice
T12966 236-237 -LRB- denotes (
T12967 237-238 CD denotes 6
T12969 238-239 SYM denotes –
T12968 239-240 CD denotes 8
T12970 241-243 NN denotes mo
T12971 244-246 IN denotes of
T12972 247-250 NN denotes age
T12973 250-251 -RRB- denotes )
T12965 252-261 VBD denotes exhibited
T12974 262-263 DT denotes a
T12976 264-272 RB denotes markedly
T12977 273-280 JJ denotes reduced
T12975 281-289 NN denotes capacity
T12978 290-292 TO denotes to
T12979 293-300 VB denotes sustain
T12980 301-308 NN denotes running
T12981 309-317 NN denotes exercise
T12982 318-319 -LRB- denotes (
T12984 319-322 NN denotes PGC
T12986 322-323 HYPH denotes -
T12985 323-325 NN denotes 1α
T12988 325-326 SYM denotes −
T12989 326-327 HYPH denotes /
T12990 327-328 SYM denotes −
T12987 329-333 NNS denotes mice
T12992 333-335 , denotes ,
T12993 335-337 CD denotes 64
T12995 338-339 SYM denotes ±
T12994 340-341 CD denotes 6
T12991 342-343 NN denotes s
T12996 343-344 : denotes ;
T12997 345-348 NN denotes age
T12999 348-349 HYPH denotes -
T12998 349-356 VBN denotes matched
T13001 357-360 NN denotes PGC
T13003 360-361 HYPH denotes -
T13002 361-363 NN denotes 1α
T13004 363-364 SYM denotes +
T13005 364-365 HYPH denotes /
T13006 365-366 SYM denotes +
T13000 367-371 NNS denotes mice
T13008 371-373 , denotes ,
T13009 373-376 CD denotes 586
T13011 377-378 SYM denotes ±
T13010 379-382 CD denotes 104
T13007 383-384 NN denotes s
T13012 384-385 : denotes ;
T13013 386-392 NN denotes Figure
T12983 393-395 NN denotes 4B
T13014 395-396 -RRB- denotes )
T13015 396-397 . denotes .
T13016 397-498 sentence denotes The same result was obtained with younger PGC-1α−/− mice, i.e., at 3.5 mo of age (unpublished data).
T13017 398-401 DT denotes The
T13019 402-406 JJ denotes same
T13018 407-413 NN denotes result
T13021 414-417 VBD denotes was
T13020 418-426 VBN denotes obtained
T13022 427-431 IN denotes with
T13023 432-439 JJR denotes younger
T13025 440-443 NN denotes PGC
T13027 443-444 HYPH denotes -
T13026 444-446 NN denotes 1α
T13028 446-447 SYM denotes −
T13029 447-448 HYPH denotes /
T13030 448-449 SYM denotes −
T13024 450-454 NNS denotes mice
T13031 454-456 , denotes ,
T13032 456-460 FW denotes i.e.
T13034 460-462 , denotes ,
T13033 462-464 IN denotes at
T13035 465-468 CD denotes 3.5
T13036 469-471 NN denotes mo
T13037 472-474 IN denotes of
T13038 475-478 NN denotes age
T13039 479-480 -LRB- denotes (
T13041 480-491 JJ denotes unpublished
T13040 492-496 NNS denotes data
T13042 496-497 -RRB- denotes )
T13043 497-498 . denotes .
T13044 498-724 sentence denotes To quantify aerobic exercise capacity, VO2max (maximum oxygen consumption, measured in milliliters of oxygen per kilogram of body weight per minute) was measured with the treadmill-running protocol using indirect calorimetry.
T13045 499-501 TO denotes To
T13046 502-510 VB denotes quantify
T13048 511-518 JJ denotes aerobic
T13050 519-527 NN denotes exercise
T13049 528-536 NN denotes capacity
T13051 536-538 , denotes ,
T13052 538-544 NN denotes VO2max
T13053 545-546 -LRB- denotes (
T13054 546-553 NN denotes maximum
T13056 554-560 NN denotes oxygen
T13055 561-572 NN denotes consumption
T13057 572-574 , denotes ,
T13058 574-582 VBN denotes measured
T13059 583-585 IN denotes in
T13060 586-597 NNS denotes milliliters
T13061 598-600 IN denotes of
T13062 601-607 NN denotes oxygen
T13063 608-611 IN denotes per
T13064 612-620 NN denotes kilogram
T13065 621-623 IN denotes of
T13066 624-628 NN denotes body
T13067 629-635 NN denotes weight
T13068 636-639 IN denotes per
T13069 640-646 NN denotes minute
T13070 646-647 -RRB- denotes )
T13071 648-651 VBD denotes was
T13047 652-660 VBN denotes measured
T13072 661-665 IN denotes with
T13073 666-669 DT denotes the
T13075 670-679 NN denotes treadmill
T13076 679-680 HYPH denotes -
T13077 680-687 VBG denotes running
T13074 688-696 NN denotes protocol
T13078 697-702 VBG denotes using
T13079 703-711 JJ denotes indirect
T13080 712-723 NN denotes calorimetry
T13081 723-724 . denotes .
T13082 724-892 sentence denotes VO2max was significantly lower for the PGC-1α−/− mice (120.9 ± 2.0 ml O2 · kg−1 · min−1) compared to PGC-1α+/+ controls (141.6 ± 2.1 ml O2 · kg−1 · min−1) (Figure 4B).
T13083 725-731 NN denotes VO2max
T13084 732-735 VBD denotes was
T13085 736-749 RB denotes significantly
T13086 750-755 JJR denotes lower
T13087 756-759 IN denotes for
T13088 760-763 DT denotes the
T13090 764-767 NN denotes PGC
T13092 767-768 HYPH denotes -
T13091 768-770 NN denotes 1α
T13093 770-771 SYM denotes −
T13094 771-772 HYPH denotes /
T13095 772-773 SYM denotes −
T13089 774-778 NNS denotes mice
T13096 779-780 -LRB- denotes (
T13098 780-785 CD denotes 120.9
T13100 786-787 SYM denotes ±
T13099 788-791 CD denotes 2.0
T13101 792-794 NN denotes ml
T13097 795-797 NN denotes O2
T13102 798-799 SYM denotes ·
T13103 800-802 NN denotes kg
T13104 802-803 SYM denotes −
T13105 803-804 CD denotes 1
T13106 805-806 SYM denotes ·
T13107 807-810 NN denotes min
T13108 810-811 SYM denotes −
T13109 811-812 CD denotes 1
T13110 812-813 -RRB- denotes )
T13111 814-822 VBN denotes compared
T13112 823-825 IN denotes to
T13113 826-829 NN denotes PGC
T13115 829-830 HYPH denotes -
T13114 830-832 NN denotes 1α
T13117 832-833 SYM denotes +
T13118 833-834 HYPH denotes /
T13119 834-835 SYM denotes +
T13116 836-844 NNS denotes controls
T13120 845-846 -LRB- denotes (
T13122 846-851 CD denotes 141.6
T13124 852-853 SYM denotes ±
T13123 854-857 CD denotes 2.1
T13125 858-860 NN denotes ml
T13121 861-863 NN denotes O2
T13126 864-865 SYM denotes ·
T13127 866-868 NN denotes kg
T13128 868-869 SYM denotes −
T13129 869-870 CD denotes 1
T13130 871-872 SYM denotes ·
T13131 873-876 NN denotes min
T13132 876-877 SYM denotes −
T13133 877-878 CD denotes 1
T13134 878-879 -RRB- denotes )
T13135 880-881 -LRB- denotes (
T13137 881-887 NN denotes Figure
T13136 888-890 NN denotes 4B
T13138 890-891 -RRB- denotes )
T13139 891-892 . denotes .
T13140 892-1021 sentence denotes To directly evaluate muscle fatigability, the force response to repetitive stimulation of isolated soleus muscle was determined.
T13141 893-895 TO denotes To
T13143 896-904 RB denotes directly
T13142 905-913 VB denotes evaluate
T13145 914-920 NN denotes muscle
T13146 921-933 NN denotes fatigability
T13147 933-935 , denotes ,
T13148 935-938 DT denotes the
T13150 939-944 NN denotes force
T13149 945-953 NN denotes response
T13151 954-956 IN denotes to
T13152 957-967 JJ denotes repetitive
T13153 968-979 NN denotes stimulation
T13154 980-982 IN denotes of
T13155 983-991 VBN denotes isolated
T13157 992-998 NN denotes soleus
T13156 999-1005 NN denotes muscle
T13158 1006-1009 VBD denotes was
T13144 1010-1020 VBN denotes determined
T13159 1020-1021 . denotes .
T13160 1021-1129 sentence denotes The capacity to generate force following a series of tetani is dependent upon mitochondrial ATP production.
T13161 1022-1025 DT denotes The
T13162 1026-1034 NN denotes capacity
T13164 1035-1037 TO denotes to
T13165 1038-1046 VB denotes generate
T13166 1047-1052 NN denotes force
T13167 1053-1062 VBG denotes following
T13168 1063-1064 DT denotes a
T13169 1065-1071 NN denotes series
T13170 1072-1074 IN denotes of
T13171 1075-1081 NNS denotes tetani
T13163 1082-1084 VBZ denotes is
T13172 1085-1094 JJ denotes dependent
T13173 1095-1099 IN denotes upon
T13174 1100-1113 JJ denotes mitochondrial
T13176 1114-1117 NN denotes ATP
T13175 1118-1128 NN denotes production
T13177 1128-1129 . denotes .
T13178 1129-1289 sentence denotes During the initial phase of the stimulation period, there was no difference in force generation in muscles isolated from PGC-1α−/− mice and PGC-1α+/+ controls.
T13179 1130-1136 IN denotes During
T13181 1137-1140 DT denotes the
T13183 1141-1148 JJ denotes initial
T13182 1149-1154 NN denotes phase
T13184 1155-1157 IN denotes of
T13185 1158-1161 DT denotes the
T13187 1162-1173 NN denotes stimulation
T13186 1174-1180 NN denotes period
T13188 1180-1182 , denotes ,
T13189 1182-1187 EX denotes there
T13180 1188-1191 VBD denotes was
T13190 1192-1194 DT denotes no
T13191 1195-1205 NN denotes difference
T13192 1206-1208 IN denotes in
T13193 1209-1214 NN denotes force
T13194 1215-1225 NN denotes generation
T13195 1226-1228 IN denotes in
T13196 1229-1236 NNS denotes muscles
T13197 1237-1245 VBN denotes isolated
T13198 1246-1250 IN denotes from
T13199 1251-1254 NN denotes PGC
T13201 1254-1255 HYPH denotes -
T13200 1255-1257 NN denotes 1α
T13203 1257-1258 SYM denotes −
T13204 1258-1259 HYPH denotes /
T13205 1259-1260 SYM denotes −
T13202 1261-1265 NNS denotes mice
T13206 1266-1269 CC denotes and
T13207 1270-1273 NN denotes PGC
T13209 1273-1274 HYPH denotes -
T13208 1274-1276 NN denotes 1α
T13211 1276-1277 SYM denotes +
T13212 1277-1278 HYPH denotes /
T13213 1278-1279 SYM denotes +
T13210 1280-1288 NNS denotes controls
T13214 1288-1289 . denotes .
T13215 1289-1544 sentence denotes However, fatigue resistance index, defined as the percent of initial force generated following a 2-min series of fatiguing contractions, was significantly lower in the PGC-1α−/− mice (14.6 ± 1.5%) compared to PGC-1α+/+ controls (24.8 ± 2.9%) (Figure 4C).
T13216 1290-1297 RB denotes However
T13218 1297-1299 , denotes ,
T13219 1299-1306 NN denotes fatigue
T13220 1307-1317 NN denotes resistance
T13221 1318-1323 NN denotes index
T13222 1323-1325 , denotes ,
T13223 1325-1332 VBN denotes defined
T13224 1333-1335 IN denotes as
T13225 1336-1339 DT denotes the
T13226 1340-1347 NN denotes percent
T13227 1348-1350 IN denotes of
T13228 1351-1358 JJ denotes initial
T13229 1359-1364 NN denotes force
T13230 1365-1374 VBN denotes generated
T13231 1375-1384 VBG denotes following
T13232 1385-1386 DT denotes a
T13234 1387-1388 CD denotes 2
T13236 1388-1389 HYPH denotes -
T13235 1389-1392 NN denotes min
T13233 1393-1399 NN denotes series
T13237 1400-1402 IN denotes of
T13238 1403-1412 VBG denotes fatiguing
T13239 1413-1425 NNS denotes contractions
T13240 1425-1427 , denotes ,
T13217 1427-1430 VBD denotes was
T13241 1431-1444 RB denotes significantly
T13242 1445-1450 JJR denotes lower
T13243 1451-1453 IN denotes in
T13244 1454-1457 DT denotes the
T13246 1458-1461 NN denotes PGC
T13248 1461-1462 HYPH denotes -
T13247 1462-1464 NN denotes 1α
T13249 1464-1465 SYM denotes −
T13250 1465-1466 HYPH denotes /
T13251 1466-1467 SYM denotes −
T13245 1468-1472 NNS denotes mice
T13252 1473-1474 -LRB- denotes (
T13254 1474-1478 CD denotes 14.6
T13256 1479-1480 SYM denotes ±
T13255 1481-1484 CD denotes 1.5
T13253 1484-1485 NN denotes %
T13257 1485-1486 -RRB- denotes )
T13258 1487-1495 VBN denotes compared
T13259 1496-1498 IN denotes to
T13260 1499-1502 NN denotes PGC
T13262 1502-1503 HYPH denotes -
T13261 1503-1505 NN denotes 1α
T13264 1505-1506 SYM denotes +
T13265 1506-1507 HYPH denotes /
T13266 1507-1508 SYM denotes +
T13263 1509-1517 NNS denotes controls
T13267 1518-1519 -LRB- denotes (
T13269 1519-1523 CD denotes 24.8
T13271 1524-1525 SYM denotes ±
T13270 1526-1529 CD denotes 2.9
T13268 1529-1530 NN denotes %
T13272 1530-1531 -RRB- denotes )
T13273 1532-1533 -LRB- denotes (
T13275 1533-1539 NN denotes Figure
T13274 1540-1542 NN denotes 4C
T13276 1542-1543 -RRB- denotes )
T13277 1543-1544 . denotes .
T13278 1544-1760 sentence denotes These results, together with the observed abnormalities in skeletal muscle mitochondrial structure and function, indicate that PGC-1α is necessary for functional adaptation of skeletal muscle to physiologic demands.
T13279 1545-1550 DT denotes These
T13280 1551-1558 NNS denotes results
T13282 1558-1560 , denotes ,
T13283 1560-1568 RB denotes together
T13284 1569-1573 IN denotes with
T13285 1574-1577 DT denotes the
T13287 1578-1586 VBN denotes observed
T13286 1587-1600 NNS denotes abnormalities
T13288 1601-1603 IN denotes in
T13289 1604-1612 JJ denotes skeletal
T13291 1613-1619 NN denotes muscle
T13292 1620-1633 JJ denotes mitochondrial
T13290 1634-1643 NN denotes structure
T13293 1644-1647 CC denotes and
T13294 1648-1656 NN denotes function
T13295 1656-1658 , denotes ,
T13281 1658-1666 VBP denotes indicate
T13296 1667-1671 IN denotes that
T13298 1672-1675 NN denotes PGC
T13300 1675-1676 HYPH denotes -
T13299 1676-1678 NN denotes 1α
T13297 1679-1681 VBZ denotes is
T13301 1682-1691 JJ denotes necessary
T13302 1692-1695 IN denotes for
T13303 1696-1706 JJ denotes functional
T13304 1707-1717 NN denotes adaptation
T13305 1718-1720 IN denotes of
T13306 1721-1729 JJ denotes skeletal
T13307 1730-1736 NN denotes muscle
T13308 1737-1739 IN denotes to
T13309 1740-1751 JJ denotes physiologic
T13310 1752-1759 NNS denotes demands
T13311 1759-1760 . denotes .
R2979 T12906 T12907 aux To,evaluate
R2981 T12907 T12909 advcl evaluate,assessed
R2982 T12908 T12907 advmod further,evaluate
R2984 T12910 T12911 det the,phenotype
R2985 T12911 T12907 dobj phenotype,evaluate
R2987 T12912 T12913 amod skeletal,muscle
R2988 T12913 T12911 compound muscle,phenotype
R2989 T12914 T12909 punct ", ",assessed
R2991 T12915 T12916 compound exercise,capacity
R2992 T12916 T12909 nsubjpass capacity,assessed
R2993 T12917 T12909 auxpass was,assessed
R2995 T12918 T12909 prep in,assessed
R2996 T12919 T12920 det the,mice
R2997 T12920 T12918 pobj mice,in
R2999 T12921 T12922 nmod PGC,1α
R3000 T12922 T12920 nmod 1α,mice
R3001 T12923 T12922 punct -,1α
R3003 T12924 T12922 punct −,1α
R3004 T12925 T12922 punct /,1α
R3005 T12926 T12922 punct −,1α
R3006 T12927 T12909 punct .,assessed
R3007 T12929 T12930 prep To,exercised
R3009 T12931 T12932 det this,end
R3010 T12932 T12929 pobj end,To
R3011 T12933 T12930 punct ", ",exercised
R3013 T12934 T12935 det the,mice
R3015 T12976 T12977 advmod markedly,reduced
R3016 T12935 T12930 nsubjpass mice,exercised
R3017 T12936 T12937 nmod PGC,1α
R3018 T12937 T12935 nmod 1α,mice
R3019 T12938 T12937 punct -,1α
R3020 T12939 T12937 punct −,1α
R3021 T12940 T12937 punct /,1α
R3022 T12977 T12975 amod reduced,capacity
R3023 T12978 T12979 aux to,sustain
R3024 T12979 T12975 acl sustain,capacity
R3025 T12941 T12937 punct −,1α
R3026 T12942 T12930 auxpass were,exercised
R3027 T12980 T12981 compound running,exercise
R3028 T12943 T12930 prep on,exercised
R3029 T12944 T12945 det a,apparatus
R3030 T12981 T12979 dobj exercise,sustain
R3031 T12945 T12943 pobj apparatus,on
R3032 T12946 T12945 amod motorized,apparatus
R3033 T12947 T12945 compound treadmill,apparatus
R3034 T12982 T12983 punct (,4B
R3035 T12948 T12930 advcl using,exercised
R3036 T12949 T12950 det a,format
R3037 T12950 T12948 dobj format,using
R3038 T12983 T12965 parataxis 4B,exhibited
R3039 T12951 T12950 nmod run,format
R3040 T12952 T12951 punct -,run
R3041 T12953 T12951 prep to,run
R3042 T12984 T12985 nmod PGC,1α
R3043 T12954 T12953 punct -,to
R3044 T12955 T12953 pobj exhaustion,to
R3045 T12956 T12930 punct .,exercised
R3046 T12985 T12987 nmod 1α,mice
R3047 T12958 T12959 nmod PGC,1α
R3048 T12986 T12985 punct -,1α
R3049 T12959 T12961 nmod 1α,mice
R3050 T12960 T12959 punct -,1α
R3051 T12987 T12991 dep mice,s
R3052 T12961 T12965 nsubj mice,exhibited
R3053 T12962 T12959 punct −,1α
R3054 T12963 T12959 punct /,1α
R3055 T12964 T12959 punct −,1α
R3056 T12966 T12961 punct (,mice
R3057 T12967 T12968 quantmod 6,8
R3058 T12988 T12985 punct −,1α
R3059 T12968 T12970 nummod 8,mo
R3060 T12969 T12968 punct –,8
R3061 T12970 T12961 npadvmod mo,mice
R3062 T12989 T12985 punct /,1α
R3063 T12971 T12970 prep of,mo
R3064 T12972 T12971 pobj age,of
R3065 T12973 T12961 punct ),mice
R3066 T12990 T12985 punct −,1α
R3067 T12974 T12975 det a,capacity
R3068 T12975 T12965 dobj capacity,exhibited
R3069 T12991 T12983 dep s,4B
R3070 T12992 T12991 punct ", ",s
R3071 T12993 T12994 quantmod 64,6
R3072 T12994 T12991 nummod 6,s
R3073 T13081 T13047 punct .,measured
R3074 T12995 T12994 punct ±,6
R3075 T13083 T13084 nsubj VO2max,was
R3076 T12996 T12983 punct ;,4B
R3077 T13085 T13086 advmod significantly,lower
R3078 T13086 T13084 acomp lower,was
R3079 T12997 T12998 npadvmod age,matched
R3080 T13087 T13084 prep for,was
R3081 T13088 T13089 det the,mice
R3082 T13089 T13087 pobj mice,for
R3083 T12998 T13000 amod matched,mice
R3084 T13090 T13091 nmod PGC,1α
R3085 T13091 T13089 nmod 1α,mice
R3086 T13092 T13091 punct -,1α
R3087 T12999 T12998 punct -,matched
R3088 T13093 T13091 punct −,1α
R3089 T13000 T13007 dep mice,s
R3090 T13001 T13002 nmod PGC,1α
R3091 T13002 T13000 nmod 1α,mice
R3092 T13094 T13091 punct /,1α
R3093 T13003 T13002 punct -,1α
R3094 T13095 T13091 punct −,1α
R3095 T13096 T13097 punct (,O2
R3096 T13004 T13002 punct +,1α
R3097 T13097 T13089 parataxis O2,mice
R3098 T13098 T13099 quantmod 120.9,2.0
R3099 T13005 T13002 punct /,1α
R3100 T13099 T13101 nummod 2.0,ml
R3101 T13100 T13099 punct ±,2.0
R3102 T13101 T13097 compound ml,O2
R3103 T13102 T13097 punct ·,O2
R3104 T13006 T13002 punct +,1α
R3105 T13103 T13097 appos kg,O2
R3106 T13104 T13105 punct −,1
R3107 T13007 T12983 dep s,4B
R3108 T13105 T13103 nummod 1,kg
R3109 T13106 T13097 punct ·,O2
R3110 T13008 T13007 punct ", ",s
R3111 T13107 T13097 appos min,O2
R3112 T13108 T13109 punct −,1
R3113 T13009 T13010 quantmod 586,104
R3114 T13109 T13107 nummod 1,min
R3115 T13110 T13084 punct ),was
R3116 T13111 T13084 prep compared,was
R3117 T13010 T13007 nummod 104,s
R3118 T13112 T13111 prep to,compared
R3119 T13113 T13114 nmod PGC,1α
R3120 T13011 T13010 punct ±,104
R3121 T13114 T13116 nmod 1α,controls
R3122 T13115 T13114 punct -,1α
R3123 T13012 T12983 punct ;,4B
R3124 T13116 T13112 pobj controls,to
R3125 T13117 T13114 punct +,1α
R3126 T13118 T13114 punct /,1α
R3127 T13013 T12983 compound Figure,4B
R3128 T13119 T13114 punct +,1α
R3129 T13120 T13121 punct (,O2
R3130 T13121 T13116 parataxis O2,controls
R3131 T13014 T12983 punct ),4B
R3132 T13122 T13123 quantmod 141.6,2.1
R3133 T13123 T13125 nummod 2.1,ml
R3134 T13124 T13123 punct ±,2.1
R3135 T13015 T12965 punct .,exhibited
R3136 T13125 T13121 compound ml,O2
R3137 T13126 T13121 punct ·,O2
R3138 T13127 T13121 appos kg,O2
R3139 T13017 T13018 det The,result
R3140 T13128 T13129 punct −,1
R3141 T13129 T13127 nummod 1,kg
R3142 T13130 T13121 punct ·,O2
R3143 T13131 T13121 appos min,O2
R3144 T13018 T13020 nsubjpass result,obtained
R3145 T13132 T13133 punct −,1
R3146 T13133 T13131 nummod 1,min
R3147 T13134 T13121 punct ),O2
R3148 T13019 T13018 amod same,result
R3149 T13135 T13136 punct (,4B
R3150 T13136 T13084 parataxis 4B,was
R3151 T13137 T13136 compound Figure,4B
R3152 T13021 T13020 auxpass was,obtained
R3153 T13138 T13136 punct ),4B
R3154 T13139 T13084 punct .,was
R3155 T13141 T13142 aux To,evaluate
R3156 T13022 T13020 prep with,obtained
R3157 T13142 T13144 advcl evaluate,determined
R3158 T13143 T13142 advmod directly,evaluate
R3159 T13145 T13146 compound muscle,fatigability
R3160 T13146 T13142 dobj fatigability,evaluate
R3161 T13147 T13144 punct ", ",determined
R3162 T13023 T13024 amod younger,mice
R3163 T13148 T13149 det the,response
R3164 T13149 T13144 nsubjpass response,determined
R3165 T13024 T13022 pobj mice,with
R3166 T13150 T13149 compound force,response
R3167 T13151 T13149 prep to,response
R3168 T13152 T13153 amod repetitive,stimulation
R3169 T13025 T13026 nmod PGC,1α
R3170 T13153 T13151 pobj stimulation,to
R3171 T13154 T13153 prep of,stimulation
R3172 T13155 T13156 amod isolated,muscle
R3173 T13026 T13024 nmod 1α,mice
R3174 T13156 T13154 pobj muscle,of
R3175 T13157 T13156 compound soleus,muscle
R3176 T13158 T13144 auxpass was,determined
R3177 T13027 T13026 punct -,1α
R3178 T13159 T13144 punct .,determined
R3179 T13161 T13162 det The,capacity
R3180 T13028 T13026 punct −,1α
R3181 T13162 T13163 nsubj capacity,is
R3182 T13164 T13165 aux to,generate
R3183 T13029 T13026 punct /,1α
R3184 T13165 T13162 acl generate,capacity
R3185 T13166 T13165 dobj force,generate
R3186 T13167 T13165 prep following,generate
R3187 T13030 T13026 punct −,1α
R3188 T13168 T13169 det a,series
R3189 T13169 T13167 pobj series,following
R3190 T13170 T13169 prep of,series
R3191 T13031 T13024 punct ", ",mice
R3192 T13171 T13170 pobj tetani,of
R3193 T13172 T13163 acomp dependent,is
R3194 T13173 T13172 prep upon,dependent
R3195 T13032 T13033 advmod i.e.,at
R3196 T13174 T13175 amod mitochondrial,production
R3197 T13175 T13173 pobj production,upon
R3198 T13176 T13175 compound ATP,production
R3199 T13033 T13024 prep at,mice
R3200 T13177 T13163 punct .,is
R3201 T13034 T13033 punct ", ",at
R3202 T13179 T13180 prep During,was
R3203 T13181 T13182 det the,phase
R3204 T13035 T13036 nummod 3.5,mo
R3205 T13182 T13179 pobj phase,During
R3206 T13183 T13182 amod initial,phase
R3207 T13184 T13182 prep of,phase
R3208 T13036 T13033 pobj mo,at
R3209 T13185 T13186 det the,period
R3210 T13186 T13184 pobj period,of
R3211 T13037 T13036 prep of,mo
R3212 T13038 T13037 pobj age,of
R3213 T13187 T13186 compound stimulation,period
R3214 T13188 T13180 punct ", ",was
R3215 T13039 T13040 punct (,data
R3216 T13189 T13180 expl there,was
R3217 T13190 T13191 det no,difference
R3218 T13191 T13180 attr difference,was
R3219 T13040 T13020 meta data,obtained
R3220 T13041 T13040 amod unpublished,data
R3221 T13192 T13191 prep in,difference
R3222 T13042 T13040 punct ),data
R3223 T13193 T13194 compound force,generation
R3224 T13194 T13192 pobj generation,in
R3225 T13195 T13180 prep in,was
R3226 T13043 T13020 punct .,obtained
R3227 T13196 T13195 pobj muscles,in
R3228 T13197 T13196 acl isolated,muscles
R3229 T13045 T13046 aux To,quantify
R3230 T13198 T13197 prep from,isolated
R3231 T13199 T13200 nmod PGC,1α
R3232 T13200 T13202 nmod 1α,mice
R3233 T13046 T13047 advcl quantify,measured
R3234 T13201 T13200 punct -,1α
R3235 T13202 T13198 pobj mice,from
R3236 T13203 T13200 punct −,1α
R3237 T13048 T13049 amod aerobic,capacity
R3238 T13204 T13200 punct /,1α
R3239 T13205 T13200 punct −,1α
R3240 T13206 T13202 cc and,mice
R3241 T13049 T13046 dobj capacity,quantify
R3242 T13207 T13208 nmod PGC,1α
R3243 T13208 T13210 nmod 1α,controls
R3244 T13209 T13208 punct -,1α
R3245 T13050 T13049 compound exercise,capacity
R3246 T13210 T13202 conj controls,mice
R3247 T13211 T13208 punct +,1α
R3248 T13212 T13208 punct /,1α
R3249 T13051 T13047 punct ", ",measured
R3250 T13213 T13208 punct +,1α
R3251 T13214 T13180 punct .,was
R3252 T13052 T13047 nsubjpass VO2max,measured
R3253 T13216 T13217 advmod However,was
R3254 T13053 T13052 punct (,VO2max
R3255 T13218 T13217 punct ", ",was
R3256 T13219 T13220 compound fatigue,resistance
R3257 T13220 T13221 compound resistance,index
R3258 T13054 T13055 compound maximum,consumption
R3259 T13221 T13217 nsubj index,was
R3260 T13222 T13221 punct ", ",index
R3261 T13055 T13052 appos consumption,VO2max
R3262 T13223 T13221 acl defined,index
R3263 T13224 T13223 prep as,defined
R3264 T13225 T13226 det the,percent
R3265 T13226 T13224 pobj percent,as
R3266 T13227 T13226 prep of,percent
R3267 T13228 T13229 amod initial,force
R3268 T13229 T13227 pobj force,of
R3269 T13056 T13055 compound oxygen,consumption
R3270 T13230 T13226 acl generated,percent
R3271 T13231 T13230 prep following,generated
R3272 T13232 T13233 det a,series
R3273 T13057 T13055 punct ", ",consumption
R3274 T13233 T13231 pobj series,following
R3275 T13234 T13235 nummod 2,min
R3276 T13058 T13055 acl measured,consumption
R3277 T13235 T13233 compound min,series
R3278 T13236 T13235 punct -,min
R3279 T13237 T13233 prep of,series
R3280 T13059 T13058 prep in,measured
R3281 T13238 T13239 amod fatiguing,contractions
R3282 T13239 T13237 pobj contractions,of
R3283 T13240 T13217 punct ", ",was
R3284 T13060 T13059 pobj milliliters,in
R3285 T13241 T13242 advmod significantly,lower
R3286 T13242 T13217 acomp lower,was
R3287 T13243 T13217 prep in,was
R3288 T13061 T13060 prep of,milliliters
R3289 T13244 T13245 det the,mice
R3290 T13245 T13243 pobj mice,in
R3291 T13246 T13247 nmod PGC,1α
R3292 T13062 T13061 pobj oxygen,of
R3293 T13247 T13245 nmod 1α,mice
R3294 T13248 T13247 punct -,1α
R3295 T13249 T13247 punct −,1α
R3296 T13063 T13060 prep per,milliliters
R3297 T13250 T13247 punct /,1α
R3298 T13251 T13247 punct −,1α
R3299 T13252 T13253 punct (,%
R3300 T13064 T13063 pobj kilogram,per
R3301 T13253 T13245 parataxis %,mice
R3302 T13254 T13255 quantmod 14.6,1.5
R3303 T13255 T13253 nummod 1.5,%
R3304 T13065 T13064 prep of,kilogram
R3305 T13256 T13255 punct ±,1.5
R3306 T13257 T13217 punct ),was
R3307 T13258 T13217 prep compared,was
R3308 T13066 T13067 compound body,weight
R3309 T13259 T13258 prep to,compared
R3310 T13260 T13261 nmod PGC,1α
R3311 T13261 T13263 nmod 1α,controls
R3312 T13067 T13065 pobj weight,of
R3313 T13262 T13261 punct -,1α
R3314 T13263 T13259 pobj controls,to
R3315 T13264 T13261 punct +,1α
R3316 T13265 T13261 punct /,1α
R3317 T13266 T13261 punct +,1α
R3318 T13267 T13268 punct (,%
R3319 T13068 T13060 prep per,milliliters
R3320 T13268 T13263 parataxis %,controls
R3321 T13269 T13270 quantmod 24.8,2.9
R3322 T13270 T13268 nummod 2.9,%
R3323 T13069 T13068 pobj minute,per
R3324 T13271 T13270 punct ±,2.9
R3325 T13272 T13268 punct ),%
R3326 T13273 T13274 punct (,4C
R3327 T13070 T13047 punct ),measured
R3328 T13071 T13047 auxpass was,measured
R3329 T13072 T13047 prep with,measured
R3330 T13274 T13217 parataxis 4C,was
R3331 T13275 T13274 compound Figure,4C
R3332 T13276 T13274 punct ),4C
R3333 T13277 T13217 punct .,was
R3334 T13073 T13074 det the,protocol
R3335 T13074 T13072 pobj protocol,with
R3336 T13279 T13280 det These,results
R3337 T13075 T13074 nmod treadmill,protocol
R3338 T13280 T13281 nsubj results,indicate
R3339 T13076 T13075 punct -,treadmill
R3340 T13282 T13280 punct ", ",results
R3341 T13077 T13075 amod running,treadmill
R3342 T13283 T13280 advmod together,results
R3343 T13284 T13283 prep with,together
R3344 T13078 T13047 advcl using,measured
R3345 T13285 T13286 det the,abnormalities
R3346 T13286 T13284 pobj abnormalities,with
R3347 T13079 T13080 amod indirect,calorimetry
R3348 T13287 T13286 amod observed,abnormalities
R3349 T13288 T13286 prep in,abnormalities
R3350 T13080 T13078 dobj calorimetry,using
R3351 T13289 T13290 amod skeletal,structure
R3352 T13290 T13288 pobj structure,in
R3353 T13291 T13290 nmod muscle,structure
R3354 T13292 T13290 amod mitochondrial,structure
R3355 T13293 T13290 cc and,structure
R3356 T13294 T13290 conj function,structure
R3357 T13295 T13281 punct ", ",indicate
R3358 T13296 T13297 mark that,is
R3359 T13297 T13281 ccomp is,indicate
R3360 T13298 T13299 compound PGC,1α
R3361 T13299 T13297 nsubj 1α,is
R3362 T13300 T13299 punct -,1α
R3363 T13301 T13297 acomp necessary,is
R3364 T13302 T13301 prep for,necessary
R3365 T13303 T13304 amod functional,adaptation
R3366 T13304 T13302 pobj adaptation,for
R3367 T13305 T13304 prep of,adaptation
R3368 T13306 T13307 amod skeletal,muscle
R3369 T13307 T13305 pobj muscle,of
R3370 T13308 T13304 prep to,adaptation
R3371 T13309 T13310 amod physiologic,demands
R3372 T13310 T13308 pobj demands,to
R3373 T13311 T13281 punct .,indicate