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PMC:2664230 / 145-2097 JSONTXT 17 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T148 0-9 NNP denotes OBJECTIVE
T149 10-13 DT denotes The
T150 14-23 NN denotes objective
T151 24-26 IN denotes of
T2464 27-31 DT denotes this
T152 27-31 DT denotes this
T2465 32-37 NN denotes study
T153 32-37 NN denotes study
T2466 38-41 VBD denotes was
T154 38-41 VBD denotes was
T155 42-44 TO denotes to
T156 45-54 VB denotes determine
T157 55-58 DT denotes the
T158 59-65 NN denotes effect
T159 66-68 IN denotes of
T160 69-80 JJ denotes nonspecific
T161 81-98 NN denotes phosphodiesterase
T162 99-109 NN denotes inhibition
T163 110-112 IN denotes on
T164 113-126 NN denotes transcription
T165 127-133 NN denotes factor
T166 134-144 NN denotes activation
T167 145-148 CC denotes and
T168 149-154 NN denotes tumor
T169 155-163 NN denotes necrosis
T170 164-176 NN denotes factor-alpha
T171 177-178 -LRB- denotes (
T172 178-183 NNP denotes TNF-α
T173 183-184 -RRB- denotes )
T174 185-195 NN denotes production
T175 196-198 IN denotes in
T176 199-217 NN denotes lipopolysaccharide
T177 218-219 -LRB- denotes (
T178 219-222 NNP denotes LPS
T179 222-223 -RRB- denotes )
T180 223-224 : denotes -
T181 224-234 VBN denotes stimulated
T182 235-240 JJ denotes human
T183 241-252 NN denotes mononuclear
T184 253-258 NNS denotes cells
T185 258-259 . denotes .
T186 261-273 NNP denotes INTRODUCTION
T187 274-277 DT denotes The
T188 278-288 NN denotes production
T189 289-291 IN denotes of
T190 292-297 NNP denotes TNF-α
T191 298-307 VBG denotes following
T192 308-311 NNP denotes LPS
T193 312-323 NN denotes stimulation
T194 324-326 VBZ denotes is
T195 327-330 CD denotes one
T196 331-333 IN denotes of
T197 334-337 DT denotes the
T198 338-341 JJ denotes key
T199 342-347 NNS denotes steps
T200 348-350 IN denotes in
T201 351-360 JJ denotes bacterial
T202 361-367 NN denotes sepsis
T203 368-371 CC denotes and
T204 372-384 NN denotes inflammation
T205 384-385 . denotes .
T206 386-389 DT denotes The
T207 390-399 NN denotes mechanism
T208 400-402 IN denotes by
T209 403-408 WDT denotes which
T210 409-426 NN denotes phosphodiesterase
T211 427-437 NN denotes inhibition
T212 438-444 VBZ denotes alters
T213 445-450 JJ denotes TNF-α
T214 451-461 NN denotes production
T215 462-464 IN denotes in
T216 465-468 DT denotes the
T217 469-477 NN denotes presence
T218 478-480 IN denotes of
T219 481-484 NNP denotes LPS
T220 485-492 VBZ denotes remains
T221 493-500 JJ denotes unclear
T222 500-501 . denotes .
T223 503-510 NNP denotes METHODS
T224 511-516 NNP denotes Human
T225 517-528 NN denotes mononuclear
T226 529-534 NNS denotes cells
T227 535-539 VBD denotes were
T228 540-550 VBN denotes stimulated
T229 551-555 IN denotes with
T230 556-559 NNP denotes LPS
T231 560-561 -LRB- denotes (
T232 561-562 CD denotes 1
T233 563-565 NN denotes μg
T234 565-566 NN denotes /
T235 566-568 NNP denotes mL
T236 568-569 -RRB- denotes )
T237 569-570 , denotes ,
T238 571-573 IN denotes in
T239 574-577 DT denotes the
T240 578-586 NN denotes presence
T241 587-590 CC denotes and
T242 591-598 NN denotes absence
T243 599-601 IN denotes of
T244 602-616 NNP denotes Pentoxifylline
T245 617-618 -LRB- denotes (
T246 618-621 NNP denotes PTX
T247 621-622 : denotes ;
T248 623-625 CD denotes 20
T249 626-628 NNP denotes mM
T250 628-629 -RRB- denotes )
T251 629-630 , denotes ,
T252 631-632 DT denotes a
T253 633-644 JJ denotes nonspecific
T254 645-662 NN denotes phosphodiesterase
T255 663-672 NN denotes inhibitor
T256 672-673 . denotes .
T257 674-681 JJ denotes Western
T258 682-690 VBG denotes blotting
T259 691-693 IN denotes of
T260 694-708 VBN denotes phosphorylated
T261 709-720 JJ denotes cytoplasmic
T262 721-726 NNP denotes I-κBα
T263 726-727 , denotes ,
T264 728-735 JJ denotes nuclear
T265 736-745 NNP denotes factor-κB
T266 746-749 NNS denotes p65
T267 750-751 -LRB- denotes (
T268 751-756 NN denotes NF-κB
T269 756-757 -RRB- denotes )
T270 757-758 , denotes ,
T271 759-762 CC denotes and
T272 763-770 JJ denotes nuclear
T273 771-784 JJ denotes cAMP-response
T274 785-792 NN denotes element
T275 793-800 JJ denotes binding
T276 801-808 NN denotes protein
T277 809-810 -LRB- denotes (
T278 810-814 NNP denotes CREB
T279 814-815 -RRB- denotes )
T280 816-819 VBD denotes was
T281 820-829 VBN denotes performed
T282 829-830 . denotes .
T283 831-834 NNP denotes DNA
T284 835-842 JJ denotes binding
T285 843-845 IN denotes of
T286 846-851 NNP denotes NF-κB
T287 852-855 CC denotes and
T288 856-860 NNP denotes CREB
T289 861-864 VBD denotes was
T290 865-873 VBN denotes verified
T291 874-876 IN denotes by
T292 877-892 JJ denotes electrophoretic
T293 893-901 NN denotes mobility
T294 902-907 NN denotes shift
T295 908-913 NN denotes assay
T296 913-914 . denotes .
T297 915-920 JJ denotes TNF-α
T298 921-927 NNS denotes levels
T299 928-932 VBD denotes were
T300 933-943 VBN denotes determined
T301 944-946 IN denotes in
T302 947-950 DT denotes the
T303 951-962 NN denotes supernatant
T304 963-965 IN denotes of
T305 966-976 VBN denotes stimulated
T306 977-982 NNS denotes cells
T307 983-985 IN denotes in
T308 986-989 DT denotes the
T309 990-998 NN denotes presence
T310 999-1002 CC denotes and
T311 1003-1010 NN denotes absence
T312 1011-1018 NNP denotes Protein
T313 1019-1025 NN denotes kinase
T314 1026-1027 DT denotes A
T315 1028-1038 NN denotes inhibition
T316 1039-1041 IN denotes by
T317 1042-1044 DT denotes an
T318 1045-1058 JJ denotes enzyme-linked
T319 1059-1072 JJ denotes immunosorbent
T320 1073-1078 NN denotes assay
T321 1079-1080 -LRB- denotes (
T322 1080-1085 NNP denotes ELISA
T323 1085-1086 -RRB- denotes )
T324 1086-1087 . denotes .
T325 1089-1096 NNS denotes RESULTS
T326 1097-1100 VBP denotes PTX
T327 1101-1104 VBD denotes was
T328 1105-1117 VBN denotes demonstrated
T329 1118-1120 TO denotes to
T330 1121-1134 RB denotes significantly
T331 1135-1141 VB denotes reduce
T332 1142-1153 JJ denotes cytoplasmic
T333 1154-1159 JJ denotes I-κBα
T334 1160-1175 NN denotes phosphorylation
T335 1175-1176 , denotes ,
T336 1177-1184 JJ denotes nuclear
T337 1185-1188 NNS denotes p65
T338 1189-1204 NN denotes phosphorylation
T339 1204-1205 , denotes ,
T340 1206-1209 CC denotes and
T341 1210-1213 DT denotes the
T342 1214-1217 NNP denotes DNA
T343 1218-1225 JJ denotes binding
T344 1226-1234 NN denotes activity
T345 1235-1237 IN denotes of
T346 1238-1243 NN denotes NF-κB
T347 1243-1244 . denotes .
T348 1245-1247 IN denotes In
T349 1248-1256 NN denotes contrast
T350 1256-1257 , denotes ,
T351 1258-1261 NNP denotes PTX
T352 1262-1270 RB denotes markedly
T353 1271-1279 VBD denotes enhanced
T354 1280-1283 DT denotes the
T355 1284-1299 NN denotes phosphorylation
T356 1300-1303 CC denotes and
T357 1304-1307 NN denotes DNA
T358 1308-1315 JJ denotes binding
T359 1316-1324 NN denotes activity
T360 1325-1327 IN denotes of
T361 1328-1332 NNP denotes CREB
T362 1332-1333 . denotes .
T363 1334-1339 NNS denotes Cells
T364 1340-1353 RB denotes concomitantly
T365 1354-1361 VBN denotes treated
T366 1362-1366 IN denotes with
T367 1367-1370 NNP denotes PTX
T368 1371-1374 CC denotes and
T369 1375-1378 NNP denotes LPS
T370 1379-1387 VBD denotes secreted
T371 1388-1395 JJ denotes similar
T372 1396-1402 NNS denotes levels
T373 1403-1405 IN denotes of
T374 1406-1411 NNP denotes TNF-α
T375 1412-1414 IN denotes in
T376 1415-1418 DT denotes the
T377 1419-1427 NN denotes presence
T378 1428-1431 CC denotes and
T379 1432-1439 NN denotes absence
T380 1440-1447 NNP denotes Protein
T381 1448-1454 NN denotes kinase
T382 1455-1456 DT denotes A
T383 1457-1467 NN denotes inhibition
T384 1467-1468 . denotes .
T385 1470-1480 NNP denotes DISCUSSION
T386 1481-1484 NNP denotes The
T387 1485-1494 VBD denotes increased
T388 1495-1500 NN denotes level
T389 1501-1503 IN denotes of
T390 1504-1508 NNP denotes cAMP
T391 1509-1513 WDT denotes that
T392 1514-1521 VBZ denotes results
T393 1522-1526 IN denotes from
T394 1527-1544 NN denotes phosphodiesterase
T395 1545-1555 NN denotes inhibition
T396 1556-1563 VBZ denotes affects
T397 1564-1575 JJ denotes cytoplasmic
T398 1576-1579 CC denotes and
T399 1580-1587 JJ denotes nuclear
T400 1588-1594 NNS denotes events
T401 1594-1595 , denotes ,
T402 1596-1605 VBG denotes resulting
T403 1606-1608 IN denotes in
T404 1609-1612 DT denotes the
T405 1613-1624 NN denotes attenuation
T406 1625-1627 IN denotes of
T407 1628-1633 NNP denotes NF-κB
T408 1634-1637 CC denotes and
T409 1638-1641 DT denotes the
T410 1642-1652 NN denotes activation
T411 1653-1655 IN denotes of
T412 1656-1660 NNP denotes CREB
T413 1661-1676 JJ denotes transcriptional
T414 1677-1680 NNP denotes DNA
T415 1681-1688 JJ denotes binding
T416 1689-1696 IN denotes through
T417 1697-1705 NNS denotes pathways
T418 1706-1710 WDT denotes that
T419 1711-1714 VBP denotes are
T420 1715-1724 RB denotes partially
T421 1725-1732 NNP denotes Protein
T422 1733-1739 NN denotes kinase
T423 1740-1753 NN denotes A-independent
T424 1753-1754 . denotes .
T425 1756-1766 NNP denotes CONCLUSION
T426 1767-1779 JJ denotes PTX-mediated
T427 1780-1797 NN denotes phosphodiesterase
T428 1798-1808 NN denotes inhibition
T429 1809-1815 VBZ denotes occurs
T430 1816-1825 RB denotes partially
T431 1826-1833 IN denotes through
T432 1834-1835 DT denotes a
T433 1836-1843 NNP denotes Protein
T434 1844-1850 NN denotes kinase
T435 1851-1864 JJ denotes A-independent
T436 1865-1872 NN denotes pathway
T437 1873-1876 CC denotes and
T438 1877-1880 MD denotes may
T439 1881-1886 VB denotes serve
T440 1887-1889 IN denotes as
T441 1890-1891 DT denotes a
T442 1892-1898 JJ denotes useful
T443 1899-1903 NN denotes tool
T444 1904-1906 IN denotes in
T445 1907-1910 DT denotes the
T446 1911-1922 NN denotes attenuation
T447 1923-1925 IN denotes of
T448 1926-1937 JJ denotes LPS-induced
T449 1938-1950 NN denotes inflammation
T450 1950-1951 . denotes .
R100 T202 T200 pobj sepsis,in
R101 T203 T202 cc and,sepsis
R102 T204 T202 conj inflammation,sepsis
R103 T205 T194 punct .,is
R104 T206 T207 det The,mechanism
R105 T207 T220 nsubj mechanism,remains
R106 T208 T212 prep by,alters
R107 T209 T208 pobj which,by
R108 T210 T211 amod phosphodiesterase,inhibition
R109 T211 T212 nsubj inhibition,alters
R110 T212 T207 relcl alters,mechanism
R111 T213 T214 amod TNF-α,production
R112 T214 T212 dobj production,alters
R113 T215 T212 prep in,alters
R114 T216 T217 det the,presence
R115 T217 T215 pobj presence,in
R116 T218 T217 prep of,presence
R117 T219 T218 pobj LPS,of
R118 T220 T220 ROOT remains,remains
R119 T221 T220 acomp unclear,remains
R120 T222 T220 punct .,remains
R121 T223 T226 compound METHODS,cells
R122 T224 T226 compound Human,cells
R123 T225 T226 compound mononuclear,cells
R124 T226 T228 nsubjpass cells,stimulated
R125 T227 T228 auxpass were,stimulated
R126 T228 T249 ccomp stimulated,mM
R127 T229 T228 prep with,stimulated
R128 T230 T229 pobj LPS,with
R129 T231 T235 punct (,mL
R130 T232 T233 nummod 1,μg
R131 T233 T235 compound μg,mL
R132 T234 T235 compound /,mL
R133 T235 T230 appos mL,LPS
R134 T236 T235 punct ),mL
R135 T237 T230 punct ",",LPS
R136 T238 T228 prep in,stimulated
R137 T239 T240 det the,presence
R138 T240 T238 pobj presence,in
R139 T241 T240 cc and,presence
R140 T242 T240 conj absence,presence
R141 T243 T242 prep of,absence
R142 T244 T243 pobj Pentoxifylline,of
R143 T245 T246 punct (,PTX
R144 T246 T244 appos PTX,Pentoxifylline
R145 T247 T249 punct ;,mM
R146 T248 T249 nummod 20,mM
R147 T249 T249 ROOT mM,mM
R148 T250 T249 punct ),mM
R149 T251 T249 punct ",",mM
R150 T252 T255 det a,inhibitor
R151 T253 T255 amod nonspecific,inhibitor
R152 T254 T255 compound phosphodiesterase,inhibitor
R153 T255 T249 appos inhibitor,mM
R154 T256 T249 punct .,mM
R155 T257 T258 amod Western,blotting
R156 T258 T281 nsubjpass blotting,performed
R157 T259 T258 prep of,blotting
R158 T260 T262 amod phosphorylated,I-κBα
R159 T261 T262 compound cytoplasmic,I-κBα
R160 T262 T259 pobj I-κBα,of
R161 T263 T262 punct ",",I-κBα
R162 T264 T266 amod nuclear,p65
R163 T265 T266 compound factor-κB,p65
R164 T266 T262 appos p65,I-κBα
R165 T267 T266 punct (,p65
R166 T268 T266 appos NF-κB,p65
R167 T269 T266 punct ),p65
R168 T270 T266 punct ",",p65
R169 T271 T266 cc and,p65
R170 T272 T274 amod nuclear,element
R171 T273 T274 amod cAMP-response,element
R172 T274 T276 compound element,protein
R173 T275 T276 amod binding,protein
R174 T276 T266 conj protein,p65
R175 T277 T278 punct (,CREB
R176 T278 T276 appos CREB,protein
R177 T279 T276 punct ),protein
R178 T280 T281 auxpass was,performed
R179 T281 T281 ROOT performed,performed
R180 T282 T281 punct .,performed
R181 T283 T284 npadvmod DNA,binding
R182 T284 T290 nsubjpass binding,verified
R183 T285 T284 prep of,binding
R184 T286 T285 pobj NF-κB,of
R185 T287 T286 cc and,NF-κB
R186 T288 T286 conj CREB,NF-κB
R187 T289 T290 auxpass was,verified
R188 T290 T290 ROOT verified,verified
R189 T291 T290 agent by,verified
R1891 T2464 T2465 det this,study
R190 T292 T295 amod electrophoretic,assay
R191 T293 T294 compound mobility,shift
R192 T294 T295 compound shift,assay
R193 T295 T291 pobj assay,by
R194 T296 T290 punct .,verified
R195 T297 T298 amod TNF-α,levels
R196 T298 T300 nsubjpass levels,determined
R197 T299 T300 auxpass were,determined
R198 T300 T300 ROOT determined,determined
R199 T301 T300 prep in,determined
R200 T302 T303 det the,supernatant
R201 T303 T301 pobj supernatant,in
R202 T304 T303 prep of,supernatant
R203 T305 T306 amod stimulated,cells
R204 T306 T304 pobj cells,of
R205 T307 T303 prep in,supernatant
R206 T308 T309 det the,presence
R207 T309 T307 pobj presence,in
R208 T310 T309 cc and,presence
R209 T311 T309 conj absence,presence
R210 T312 T313 compound Protein,kinase
R211 T313 T313 ROOT kinase,kinase
R212 T314 T315 det A,inhibition
R213 T315 T315 ROOT inhibition,inhibition
R214 T316 T315 prep by,inhibition
R215 T317 T320 det an,assay
R216 T318 T320 nmod enzyme-linked,assay
R217 T319 T320 compound immunosorbent,assay
R218 T320 T316 pobj assay,by
R219 T321 T320 punct (,assay
R220 T322 T320 appos ELISA,assay
R221 T323 T320 punct ),assay
R222 T324 T315 punct .,inhibition
R223 T325 T326 compound RESULTS,PTX
R224 T326 T328 nsubjpass PTX,demonstrated
R225 T327 T328 auxpass was,demonstrated
R226 T328 T328 ROOT demonstrated,demonstrated
R227 T329 T331 aux to,reduce
R228 T330 T331 advmod significantly,reduce
R229 T331 T328 xcomp reduce,demonstrated
R230 T332 T334 amod cytoplasmic,phosphorylation
R231 T333 T334 amod I-κBα,phosphorylation
R232 T334 T331 dobj phosphorylation,reduce
R233 T335 T334 punct ",",phosphorylation
R234 T336 T337 amod nuclear,p65
R235 T337 T338 compound p65,phosphorylation
R236 T338 T334 appos phosphorylation,phosphorylation
R237 T339 T338 punct ",",phosphorylation
R238 T340 T338 cc and,phosphorylation
R239 T341 T344 det the,activity
R240 T342 T344 nmod DNA,activity
R241 T343 T344 amod binding,activity
R242 T344 T338 conj activity,phosphorylation
R243 T345 T344 prep of,activity
R244 T346 T345 pobj NF-κB,of
R245 T347 T328 punct .,demonstrated
R246 T348 T353 prep In,enhanced
R247 T349 T348 pobj contrast,In
R248 T350 T353 punct ",",enhanced
R249 T351 T353 nsubj PTX,enhanced
R250 T352 T353 advmod markedly,enhanced
R251 T353 T353 ROOT enhanced,enhanced
R252 T354 T355 det the,phosphorylation
R253 T355 T353 dobj phosphorylation,enhanced
R254 T356 T355 cc and,phosphorylation
R255 T357 T359 amod DNA,activity
R256 T358 T359 amod binding,activity
R257 T359 T355 conj activity,phosphorylation
R258 T360 T355 prep of,phosphorylation
R259 T361 T360 pobj CREB,of
R260 T362 T353 punct .,enhanced
R261 T363 T370 nsubj Cells,secreted
R262 T364 T365 advmod concomitantly,treated
R263 T365 T363 acl treated,Cells
R264 T366 T365 prep with,treated
R265 T367 T366 pobj PTX,with
R266 T368 T367 cc and,PTX
R267 T369 T367 conj LPS,PTX
R268 T370 T370 ROOT secreted,secreted
R269 T371 T372 amod similar,levels
R270 T372 T370 dobj levels,secreted
R271 T373 T372 prep of,levels
R272 T374 T373 pobj TNF-α,of
R273 T375 T370 prep in,secreted
R274 T376 T377 det the,presence
R275 T377 T375 pobj presence,in
R276 T378 T377 cc and,presence
R277 T379 T377 conj absence,presence
R278 T380 T381 compound Protein,kinase
R279 T381 T381 ROOT kinase,kinase
R280 T382 T383 det A,inhibition
R281 T383 T383 ROOT inhibition,inhibition
R282 T384 T383 punct .,inhibition
R283 T385 T396 nsubj DISCUSSION,affects
R284 T386 T388 det The,level
R285 T387 T388 amod increased,level
R286 T388 T396 nsubj level,affects
R287 T389 T388 prep of,level
R288 T390 T389 pobj cAMP,of
R289 T391 T392 nsubj that,results
R290 T392 T388 relcl results,level
R291 T393 T392 prep from,results
R292 T394 T395 amod phosphodiesterase,inhibition
R293 T395 T393 pobj inhibition,from
R294 T396 T396 ROOT affects,affects
R295 T397 T400 amod cytoplasmic,events
R296 T398 T397 cc and,cytoplasmic
R297 T399 T397 conj nuclear,cytoplasmic
R298 T400 T396 dobj events,affects
R299 T401 T396 punct ",",affects
R300 T402 T396 advcl resulting,affects
R301 T403 T402 prep in,resulting
R302 T404 T405 det the,attenuation
R303 T405 T403 pobj attenuation,in
R304 T406 T405 prep of,attenuation
R305 T407 T406 pobj NF-κB,of
R306 T408 T405 cc and,attenuation
R307 T409 T410 det the,activation
R308 T410 T405 conj activation,attenuation
R309 T411 T410 prep of,activation
R310 T412 T414 compound CREB,DNA
R311 T413 T414 compound transcriptional,DNA
R312 T414 T411 pobj DNA,of
R313 T415 T410 amod binding,activation
R314 T416 T415 prep through,binding
R315 T417 T416 pobj pathways,through
R316 T418 T419 nsubj that,are
R317 T419 T417 relcl are,pathways
R318 T420 T419 advmod partially,are
R319 T421 T423 compound Protein,A-independent
R320 T422 T423 compound kinase,A-independent
R321 T423 T419 attr A-independent,are
R322 T424 T396 punct .,affects
R323 T425 T428 nmod CONCLUSION,inhibition
R324 T426 T428 amod PTX-mediated,inhibition
R325 T427 T428 compound phosphodiesterase,inhibition
R326 T428 T429 nsubj inhibition,occurs
R327 T429 T429 ROOT occurs,occurs
R328 T430 T431 advmod partially,through
R329 T431 T429 prep through,occurs
R330 T432 T436 det a,pathway
R331 T433 T436 nmod Protein,pathway
R332 T434 T436 nmod kinase,pathway
R333 T435 T436 compound A-independent,pathway
R334 T436 T431 pobj pathway,through
R335 T437 T429 cc and,occurs
R336 T438 T439 aux may,serve
R337 T439 T429 conj serve,occurs
R338 T440 T439 prep as,serve
R339 T441 T443 det a,tool
R340 T442 T443 amod useful,tool
R341 T443 T440 pobj tool,as
R342 T444 T443 prep in,tool
R343 T445 T446 det the,attenuation
R344 T446 T444 pobj attenuation,in
R345 T447 T446 prep of,attenuation
R346 T448 T449 amod LPS-induced,inflammation
R347 T449 T447 pobj inflammation,of
R348 T450 T429 punct .,occurs
R60 T162 T159 pobj inhibition,of
R61 T163 T162 prep on,inhibition
R62 T164 T165 compound transcription,factor
R63 T165 T166 compound factor,activation
R64 T166 T163 pobj activation,on
R65 T167 T166 cc and,activation
R66 T168 T169 compound tumor,necrosis
R67 T169 T170 compound necrosis,factor-alpha
R68 T170 T166 conj factor-alpha,activation
R69 T171 T172 punct (,TNF-α
R70 T172 T170 appos TNF-α,factor-alpha
R71 T173 T170 punct ),factor-alpha
R72 T174 T166 conj production,activation
R73 T175 T174 prep in,production
R74 T176 T175 pobj lipopolysaccharide,in
R75 T177 T178 punct (,LPS
R76 T178 T176 appos LPS,lipopolysaccharide
R77 T179 T176 punct ),lipopolysaccharide
R774 T149 T150 det The,objective
R775 T150 T154 nsubj objective,was
R776 T151 T150 prep of,objective
R777 T152 T153 det this,study
R778 T153 T151 pobj study,of
R779 T154 T154 ROOT was,was
R78 T180 T162 punct -,inhibition
R780 T155 T156 aux to,determine
R781 T156 T154 xcomp determine,was
R782 T157 T158 det the,effect
R783 T158 T156 dobj effect,determine
R784 T159 T158 prep of,effect
R785 T160 T162 amod nonspecific,inhibition
R786 T161 T162 compound phosphodiesterase,inhibition
R79 T181 T154 conj stimulated,was
R80 T182 T184 amod human,cells
R81 T183 T184 compound mononuclear,cells
R82 T184 T181 dobj cells,stimulated
R83 T185 T154 punct .,was
R84 T186 T194 advmod INTRODUCTION,is
R85 T187 T188 det The,production
R86 T188 T194 nsubj production,is
R87 T189 T188 prep of,production
R88 T190 T189 pobj TNF-α,of
R89 T191 T188 prep following,production
R90 T192 T193 compound LPS,stimulation
R91 T193 T191 pobj stimulation,following
R92 T194 T194 ROOT is,is
R93 T195 T194 attr one,is
R94 T196 T195 prep of,one
R95 T197 T199 det the,steps
R96 T198 T199 amod key,steps
R97 T199 T196 pobj steps,of
R98 T200 T199 prep in,steps
R99 T201 T202 amod bacterial,sepsis