PubMed:16423994 / 587-926 JSONTXT 3 Projects

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Id Subject Object Predicate Lexical cue
T4 0-339 DRI_Approach denotes Here, we applied a recently developed method, multiplex ligation-dependent probe amplification, to study MLH1/MSH2 copy number changes in 16 unrelated Swiss HNPCC patients, whose cancers displayed microsatellite instability and loss of MLH1 or MSH2 expression, but in whom no germ line mutation could be detected by conventional screening.