LitCovid-sentences  

PMC:7736111 / 143387-145047 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T998 0-189 Sentence denotes The late robust immune response generated by excessive infiltration of innate immune cells, proinflammatory cytokines, along with activated lymphocytes causes extensive damage to the lungs.
T999 190-372 Sentence denotes By this time, the injury incurred by the hyperactivated innate immune system far bypasses the damage by the virus, eventually leading to respiratory collapse and multi-organ failure.
T1000 373-599 Sentence denotes Taking cues from animal models and post-mortem samples of deceased SARS-CoV infected patients, a comprehensive picture of the clinical and molecular pattern of lung damage has emerged (Leung et al., 2005) as shown in Figure 5.
T1001 600-665 Sentence denotes These events proceed in a sequential and well-coordinated manner.
T1002 666-925 Sentence denotes Excessive alveolar epithelial cell death, loss of extracellular matrix, deposition of cellular debris, and formation of hyaline membrane starts early along with bronchiolar and alveolar epithelial cell denudation, referred to as diffuse alveolar damage (DAD).
T1003 926-1175 Sentence denotes These events are proceeded by desquamation of the alveolar and bronchial epithelial lining, altered permeability of the alveolar-vascular barrier, interstitial pulmonary edema, thrombosis, coagulation, and fibrin deposition (Gralinski et al., 2013).
T1004 1176-1376 Sentence denotes Finally, the SARS-CoV disease progresses to a more severe fibrotic stage with increased fibroblast cell proliferation, interstitial fibrosis, collagen deposition, and complete collapse of the airways.
T1005 1377-1510 Sentence denotes The contents are released to the secondary tissues along with the proinflammatory cytokines, which may result in multi-organ failure.
T1006 1511-1660 Sentence denotes These changes are orchestrated by a coordinated action of molecular events that are ever-expanding (Chong et al., 2004; Jih, 2005; Yen et al., 2006).