| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T367 |
0-230 |
Sentence |
denotes |
The release of acetylcholine (a neurotransmitter that regulates cognition) at the synaptic cleft of the neuromuscular junction is essential for motor neurotransmission, which controls excitation-contraction coupling and cell size. |
| T368 |
231-359 |
Sentence |
denotes |
However, free radicals, cytokines, and AGEs impair neurotransmission by altering the production of acetylcholine [6,21,149,153]. |
| T369 |
360-452 |
Sentence |
denotes |
On the other hand, upregulation of acetylcholine receptors improves neurotransmission [154]. |
| T370 |
453-578 |
Sentence |
denotes |
Treatment with royal jelly may correct acetylcholine neurotransmission given its high content of acetylcholine (4–8 mM) [60]. |
| T371 |
579-819 |
Sentence |
denotes |
In addition, royal jelly, propolis, and bee pollen are rich in antioxidant elements that have a potential to scavenge ROS and mitigate other pathologies that contribute to acetylcholine deficiency (e.g., neuroinflammation) [73,101,102,103]. |
| T372 |
820-1126 |
Sentence |
denotes |
In this respect, treatment of experimental models of carrageenan-induced hind paw edema with hydroalcoholic extract of red propolis and its biomarker, formononetin, is reported to inhibit leukocyte migration and ameliorate inflammatory neurogenic pain induced by injections of formalin and glutamate [115]. |
| T373 |
1127-1218 |
Sentence |
denotes |
However, investigations of the action of bee products on neurotransmission are very scarce. |
