PMC:7600245 / 92182-92845 7 Projects
Annnotations
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T745 | 116-215 | Sentence | denotes | EIDD-2801 is an orally bioavailable nucleoside derivative that is under development for SARS-CoV-2. |
T746 | 216-607 | Sentence | denotes | Also depicted is its activation to the corresponding tri-phosphorylated form which exhibits a broad-spectrum antiviral activity against various RNA viruses, including coronaviruses with resistance mutations to remdesivir. (B) The active form exists in two forms: the oxime form which mimics uridine and pairs with adenosine, while the other tautomer mimics cytidine and pairs with guanosine. |
T747 | 608-663 | Sentence | denotes | The drug eventually leads to a viral error catastrophe. |