PMC:7600245 / 75999-77145 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T596 0-86 Sentence denotes On the one hand, resveratrol is a natural polyphenolic stilbene derivative (Figure 9).
T597 87-236 Sentence denotes Resveratrol exhibits several biological activities, including antioxidant, antitumor, anti-inflammatory, oxygen scavenging, and antiviral activities.
T598 237-317 Sentence denotes Resveratrol inhibits TNF-induced activation of NF-κB in a dose-dependent manner.
T599 318-387 Sentence denotes Furthermore, it inhibits cyclooxygenase and hydro-peroxidase enzymes.
T600 388-512 Sentence denotes Not only that but it also inhibits vascular cell adhesion molecule expression and vascular smooth muscle cell proliferation.
T601 513-644 Sentence denotes It also stimulates endothelial nitric oxide synthase activity and inhibits platelet aggregation and LDL peroxidation [276,277,278].
T602 645-731 Sentence denotes All these effects are expected to help fight COVID-19 infection and its complications.
T603 732-857 Sentence denotes Importantly, resveratrol significantly inhibited MERS-CoV replication in vitro mainly by inhibiting the RNA production [279].
T604 858-960 Sentence denotes Resveratrol also inhibited the replication of duck enteritis virus [280] and pseudorabies virus [281].
T605 961-1146 Sentence denotes Accordingly, the safety and efficacy of resveratrol in COVID-19 patients are being tested in a randomized double-blind, placebo-controlled proof-of-concept trial (NCT04400890; n = 200).