Id |
Subject |
Object |
Predicate |
Lexical cue |
T596 |
0-86 |
Sentence |
denotes |
On the one hand, resveratrol is a natural polyphenolic stilbene derivative (Figure 9). |
T597 |
87-236 |
Sentence |
denotes |
Resveratrol exhibits several biological activities, including antioxidant, antitumor, anti-inflammatory, oxygen scavenging, and antiviral activities. |
T598 |
237-317 |
Sentence |
denotes |
Resveratrol inhibits TNF-induced activation of NF-κB in a dose-dependent manner. |
T599 |
318-387 |
Sentence |
denotes |
Furthermore, it inhibits cyclooxygenase and hydro-peroxidase enzymes. |
T600 |
388-512 |
Sentence |
denotes |
Not only that but it also inhibits vascular cell adhesion molecule expression and vascular smooth muscle cell proliferation. |
T601 |
513-644 |
Sentence |
denotes |
It also stimulates endothelial nitric oxide synthase activity and inhibits platelet aggregation and LDL peroxidation [276,277,278]. |
T602 |
645-731 |
Sentence |
denotes |
All these effects are expected to help fight COVID-19 infection and its complications. |
T603 |
732-857 |
Sentence |
denotes |
Importantly, resveratrol significantly inhibited MERS-CoV replication in vitro mainly by inhibiting the RNA production [279]. |
T604 |
858-960 |
Sentence |
denotes |
Resveratrol also inhibited the replication of duck enteritis virus [280] and pseudorabies virus [281]. |
T605 |
961-1146 |
Sentence |
denotes |
Accordingly, the safety and efficacy of resveratrol in COVID-19 patients are being tested in a randomized double-blind, placebo-controlled proof-of-concept trial (NCT04400890; n = 200). |