PMC:7600245 / 68384-69158 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T530 0-5 Sentence denotes 4.16.
T531 6-16 Sentence denotes Artesunate
T532 17-89 Sentence denotes It is a polycyclic natural product with endoperoxide moiety (Figure S6).
T533 90-131 Sentence denotes It is parenterally used to treat malaria.
T534 132-266 Sentence denotes Initially, there was not enough information about its efficacy against SARS-CoV, except the results of herbal extract screening [246].
T535 267-454 Sentence denotes It is now being evaluated in few clinical trials alone (NCT04387240; n = 22) or in combination with pyronaridine, another antimalarial drug (NCT04475107; n = 76 and NCT04532931; n = 250).
T536 455-600 Sentence denotes In particular, the combination exhibited antiviral activity against SARS-CoV-2 and influenza viruses in human lung epithelial Calu-3 cells [247].
T537 601-774 Sentence denotes Other artemisinin-based combinations that appear to be on the rise for potentially treating COVID-19 are mefloquine-artesunate [248] and arteannuin B and lumefantrine [249].