LitCovid-sentences  

PMC:7551987 / 12965-14596 JSONTXT 3 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T88 0-70 Sentence denotes In this study, we define virulence as the capacity to cause a disease.
T89 71-257 Sentence denotes In order to measure it, we utilize a set of parameters that uniformly increase the rate or probability of causing symptomatic disease or the severity of those symptoms (including death).
T90 258-558 Sentence denotes Our definition is more comprehensive than many other models of parasite virulence (e.g., [4,13]), which tend to focus on a single aspect of the natural history of disease associated with harm to a host (e.g., the fitness consequences of an infection on the host population or the case fatality rate).
T91 559-810 Sentence denotes Instead of having to justify a definition built around a single term (e.g., the term associated with fatality), we took a collective approach to defining virulence through all terms that foment the viral-induced onset of symptomatic disease and death.
T92 811-978 Sentence denotes This definition allows for the reality of pleiotropic effects in viral pathogens, where adaptations can have multiple effects on the natural history of disease [2,33].
T93 979-1084 Sentence denotes Our definition of virulence emphasizes terms that influence host wellness and/or are symptoms of disease.
T94 1085-1259 Sentence denotes The iteration of virulence used in this study also undermines the potential for overly weighting only one or a small number of parameters under a large umbrella of virulence.
T95 1260-1567 Sentence denotes Because so many varying definitions exist for virulence, we have also performed calculations according to a different definition of virulence, one that exclusively considers terms that have a detrimental direct effect on the host and neither of the terms that reflect symptoms of severe disease (𝜎a and 𝜎I).
T96 1568-1631 Sentence denotes These calculations can be found in the Supplementary Materials.