Id |
Subject |
Object |
Predicate |
Lexical cue |
T633 |
0-141 |
Sentence |
denotes |
Afatinib has also been tested in combination with nintedanib in a Phase I dose-escalation study in patients with advanced solid tumors (182). |
T634 |
142-305 |
Sentence |
denotes |
It was determined that afatinib at 10 mg/day combined with nintedanib at 200 mg twice a day had a manageable safety profile, however the doses were subtherapeutic. |
T635 |
306-534 |
Sentence |
denotes |
The antifibrotic and anti-inflammatory potential of afatinib and nintedanib, coupled with key virus-associated protein targets for each (Table 2, Fig. 3), warrant investigation of this drug combination for treatment of COVID-19. |