Id |
Subject |
Object |
Predicate |
Lexical cue |
T3 |
0-106 |
Sentence |
denotes |
COVID-19 is currently a global pandemic, but human immune responses to the virus remain poorly understood. |
T4 |
107-221 |
Sentence |
denotes |
We analyzed 125 COVID-19 patients, and compared recovered to healthy individuals using high dimensional cytometry. |
T5 |
222-360 |
Sentence |
denotes |
Integrated analysis of ~200 immune and ~50 clinical features revealed activation of T cell and B cell subsets in a proportion of patients. |
T6 |
361-509 |
Sentence |
denotes |
A subgroup of patients had T cell activation characteristic of acute viral infection and plasmablast responses reaching >30% of circulating B cells. |
T7 |
510-596 |
Sentence |
denotes |
However, another subgroup had lymphocyte activation comparable to uninfected subjects. |
T8 |
597-714 |
Sentence |
denotes |
Stable versus dynamic immunological signatures were identified and linked to trajectories of disease severity change. |
T9 |
715-828 |
Sentence |
denotes |
These analyses identified three “immunotypes” associated with poor clinical trajectories versus improving health. |
T10 |
829-926 |
Sentence |
denotes |
These immunotypes may have implications for the design of therapeutics and vaccines for COVID-19. |