PMC:7402624 / 112-1038 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T3 0-106 Sentence denotes COVID-19 is currently a global pandemic, but human immune responses to the virus remain poorly understood.
T4 107-221 Sentence denotes We analyzed 125 COVID-19 patients, and compared recovered to healthy individuals using high dimensional cytometry.
T5 222-360 Sentence denotes Integrated analysis of ~200 immune and ~50 clinical features revealed activation of T cell and B cell subsets in a proportion of patients.
T6 361-509 Sentence denotes A subgroup of patients had T cell activation characteristic of acute viral infection and plasmablast responses reaching >30% of circulating B cells.
T7 510-596 Sentence denotes However, another subgroup had lymphocyte activation comparable to uninfected subjects.
T8 597-714 Sentence denotes Stable versus dynamic immunological signatures were identified and linked to trajectories of disease severity change.
T9 715-828 Sentence denotes These analyses identified three “immunotypes” associated with poor clinical trajectories versus improving health.
T10 829-926 Sentence denotes These immunotypes may have implications for the design of therapeutics and vaccines for COVID-19.