Id |
Subject |
Object |
Predicate |
Lexical cue |
T1085 |
0-10 |
Sentence |
denotes |
Liang 2020 |
T1086 |
11-32 |
Sentence |
denotes |
Study characteristics |
T1087 |
33-295 |
Sentence |
denotes |
Patient Sampling Purpose: to estimate the prevalence of COVID‐19 in pneumonias during this period and to find the unique features of COVID‐19 as compared to pneumonias caused by other agentsDesign: cross‐sectional, single‐centre, retrospective studyRecruitment: |
T1088 |
296-386 |
Sentence |
denotes |
342 cases of pneumonia were diagnosed in Fever Clinic in Peking University Third Hospital. |
T1089 |
387-651 |
Sentence |
denotes |
From these patients, 88 were reviewed by panel discussion as possible or probable cases of COVID‐19, and received 2019‐nCoV detection by RT‐PCRSample size: n = 88 (21 cases)Inclusion criteria: patients visiting the Fever Clinic at Peking University Third Hospital. |
T1090 |
652-1037 |
Sentence |
denotes |
Based on epidemiological history, epidemiological evidence, fever and/or respiratory symptoms, chest radiological findings and WBC results, cases with possible or probable COVID‐19 were sent for panel discussion and then for 2019‐nCoV detection by RT‐PCRExclusion criteria: COVID‐19 unlikely by panel discussion; lack of CT scan or no signs of pneumonia on CT scan; paediatric patients |
T1091 |
1038-1090 |
Sentence |
denotes |
Patient characteristics and setting Facility cases: |
T1092 |
1091-1173 |
Sentence |
denotes |
2019‐nCoV real‐time PCR testing, which was positive in 19 cases (confirmed cases). |
T1093 |
1174-1530 |
Sentence |
denotes |
In another 2 patients, though PCR testing was negative, a clinical diagnosis was made according to
epidemiological evidence, consistent clinical and CT findings (clinical cases)Facility controls: for the cases with negative viral detection, the diagnosis of COVID‐19 was excluded based on inconsistent epidemiological, clinical or radiological dataCountry: |
T1094 |
1531-1542 |
Sentence |
denotes |
ChinaDates: |
T1095 |
1543-1627 |
Sentence |
denotes |
21 January 2020‐15 February 2020SymptomsFever with a mean body temperature of 37.8 C |
T1096 |
1628-1633 |
Sentence |
denotes |
Cough |
T1097 |
1634-1647 |
Sentence |
denotes |
Expectoration |
T1098 |
1648-1655 |
Sentence |
denotes |
Fatigue |
T1099 |
1656-1664 |
Sentence |
denotes |
Headache |
T1100 |
1665-1674 |
Sentence |
denotes |
Dizziness |
T1101 |
1675-1694 |
Sentence |
denotes |
Shortness of breath |
T1102 |
1695-1716 |
Sentence |
denotes |
Myalgia or arthralgia |
T1103 |
1717-1728 |
Sentence |
denotes |
Sore throat |
T1104 |
1729-1757 |
Sentence |
denotes |
Nasal symptoms and diarrhoea |
T1105 |
1758-1915 |
Sentence |
denotes |
Severity of COVID‐19Mild‐moderate: fever and/or respiratory symptoms with pneumonia in radiology examination, without signs of severe or very severe diseases |
T1106 |
1916-2028 |
Sentence |
denotes |
Severe: presence of 1 of the following: respiratory rate ≥ 30 beat/min; SpO2 ≤ 93% at rest; PaO2/FiO2 ≤ 300 mmHg |
T1107 |
2029-2206 |
Sentence |
denotes |
Very severe: presence of 1 of the following: severe respiratory failure requiring mechanical ventilation; shock; complicated with other organ failure and requiring ICU admission |
T1108 |
2207-2305 |
Sentence |
denotes |
Demographics: COVID‐group only: median age was 42.0 years (25th‐75th percentile, 34.5‐66.0 years). |
T1109 |
2306-2318 |
Sentence |
denotes |
Range 24‐85. |
T1110 |
2319-2331 |
Sentence |
denotes |
Male/female: |
T1111 |
2332-2370 |
Sentence |
denotes |
11 (52.4%)/10 (47.6%)Exposure history: |
T1112 |
2371-2433 |
Sentence |
denotes |
19/21 (90.5%) had a clear epidemiological history of COVID‐19. |
T1113 |
2434-2513 |
Sentence |
denotes |
7 patients, from 5 family clusters, had close contact with their family members |
T1114 |
2514-2571 |
Sentence |
denotes |
Index tests Fever with a mean body temperature of 37.8 C |
T1115 |
2572-2577 |
Sentence |
denotes |
Cough |
T1116 |
2578-2591 |
Sentence |
denotes |
Expectoration |
T1117 |
2592-2599 |
Sentence |
denotes |
Fatigue |
T1118 |
2600-2608 |
Sentence |
denotes |
Headache |
T1119 |
2609-2618 |
Sentence |
denotes |
Dizziness |
T1120 |
2619-2638 |
Sentence |
denotes |
Shortness of breath |
T1121 |
2639-2660 |
Sentence |
denotes |
Myalgia or arthralgia |
T1122 |
2661-2672 |
Sentence |
denotes |
Sore throat |
T1123 |
2673-2701 |
Sentence |
denotes |
Nasal symptoms and diarrhoea |
T1124 |
2702-2768 |
Sentence |
denotes |
Target condition and reference standard(s) TC: COVID‐19 pneumonia |
T1125 |
2769-2772 |
Sentence |
denotes |
RS: |
T1126 |
2773-2910 |
Sentence |
denotes |
2019‐nCoV real‐time PCR testing or clinical diagnosis was made according to epidemiological evidence, consistent clinical and CT findings |
T1127 |
2911-2955 |
Sentence |
denotes |
Flow and timing Time interval not specified |
T1128 |
2956-2970 |
Sentence |
denotes |
Comparative |
T1129 |
2971-2979 |
Sentence |
denotes |
Notes |
T1130 |
2980-3002 |
Sentence |
denotes |
Methodological quality |
T1131 |
3003-3068 |
Sentence |
denotes |
Item Authors' judgement Risk of bias Applicability concerns |
T1132 |
3069-3078 |
Sentence |
denotes |
DOMAIN 1: |
T1133 |
3079-3096 |
Sentence |
denotes |
Patient Selection |
T1134 |
3097-3153 |
Sentence |
denotes |
Was a consecutive or random sample of patients enrolled? |
T1135 |
3155-3168 |
Sentence |
denotes |
Unclear |
T1136 |
3169-3203 |
Sentence |
denotes |
Was a case‐control design avoided? |
T1137 |
3205-3214 |
Sentence |
denotes |
Yes |
T1138 |
3215-3260 |
Sentence |
denotes |
Did the study avoid inappropriate exclusions? |
T1139 |
3262-3270 |
Sentence |
denotes |
No |
T1140 |
3271-3316 |
Sentence |
denotes |
Did the study avoid inappropriate inclusions? |
T1141 |
3318-3326 |
Sentence |
denotes |
No |
T1142 |
3327-3397 |
Sentence |
denotes |
Could the selection of patients have introduced bias? High risk |
T1143 |
3398-3501 |
Sentence |
denotes |
Are there concerns that the included patients and setting do not match the review question? High |
T1144 |
3502-3511 |
Sentence |
denotes |
DOMAIN 2: |
T1145 |
3512-3534 |
Sentence |
denotes |
Index Test (All tests) |
T1146 |
3535-3634 |
Sentence |
denotes |
Were the index test results interpreted without knowledge of the results of the reference standard? |
T1147 |
3636-3645 |
Sentence |
denotes |
Yes |
T1148 |
3646-3692 |
Sentence |
denotes |
If a threshold was used, was it pre‐specified? |
T1149 |
3694-3702 |
Sentence |
denotes |
No |
T1150 |
3703-3795 |
Sentence |
denotes |
Could the conduct or interpretation of the index test have introduced bias? High risk |
T1151 |
3796-3918 |
Sentence |
denotes |
Are there concerns that the index test, its conduct, or interpretation differ from the review question? Low concern |
T1152 |
3919-3928 |
Sentence |
denotes |
DOMAIN 3: |
T1153 |
3929-3947 |
Sentence |
denotes |
Reference Standard |
T1154 |
3948-4025 |
Sentence |
denotes |
Is the reference standards likely to correctly classify the target condition? |
T1155 |
4027-4036 |
Sentence |
denotes |
Yes |
T1156 |
4037-4137 |
Sentence |
denotes |
Were the reference standard results interpreted without knowledge of the results of the index tests? |
T1157 |
4139-4147 |
Sentence |
denotes |
No |
T1158 |
4148-4250 |
Sentence |
denotes |
Could the reference standard, its conduct, or its interpretation have introduced bias? Low risk |
T1159 |
4251-4380 |
Sentence |
denotes |
Are there concerns that the target condition as defined by the reference standard does not match the question? Low concern |
T1160 |
4381-4390 |
Sentence |
denotes |
DOMAIN 4: |
T1161 |
4391-4406 |
Sentence |
denotes |
Flow and Timing |
T1162 |
4407-4483 |
Sentence |
denotes |
Was there an appropriate interval between index test and reference standard? |
T1163 |
4485-4498 |
Sentence |
denotes |
Unclear |
T1164 |
4499-4552 |
Sentence |
denotes |
Did all patients receive the same reference standard? |
T1165 |
4554-4563 |
Sentence |
denotes |
Yes |
T1166 |
4564-4607 |
Sentence |
denotes |
Were all patients included in the analysis? |
T1167 |
4609-4618 |
Sentence |
denotes |
Yes |
T1168 |
4619-4680 |
Sentence |
denotes |
Could the patient flow have introduced bias? High risk |