Id |
Subject |
Object |
Predicate |
Lexical cue |
T44 |
0-121 |
Sentence |
denotes |
In the so‐called receptor‐binding domain of the spike protein there are 22 glycan‐binding sites (Shahajan, Supekar et al. |
T45 |
122-128 |
Sentence |
denotes |
2020). |
T46 |
129-252 |
Sentence |
denotes |
High mannose, hybrid and complex‐type glycans across the N‐glycosylation sites have been identified with mass spectrometry. |
T47 |
253-461 |
Sentence |
denotes |
One could imagine building a therapeutic which might contain the carbohydrates, or a suitable mimic, of the spike protein coupled to a carrier molecule, much in a similar fashion to how PPSGG was constructed. |
T48 |
462-613 |
Sentence |
denotes |
Such a “decoy” carbohydrate could block the binding and subsequent internalization of COViD‐19 to its receptor, angiotensin converting enzyme‐2 (ACE2). |
T49 |
614-715 |
Sentence |
denotes |
In addition, spike carbohydrate clusters coupled to a carrier might proof to be an effective vaccine. |
T50 |
716-848 |
Sentence |
denotes |
Both the pneumococcal vaccine and the meningococcal vaccines target polysaccharides in pneumococcus and meningococcus, respectively. |
T51 |
849-969 |
Sentence |
denotes |
They couple the appropriate polysaccharide to a suitable carrier to achieve potent carbohydrate‐specific immunogenicity. |