| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T459 |
0-139 |
Sentence |
denotes |
Non-steroidal anti-inflammatory drugs, or NSAIDs, are one of the most commonly prescribed drugs for treating fever, pain, and inflammation. |
| T460 |
140-229 |
Sentence |
denotes |
NSAIDs include over-the-counter household names such as ibuprofen, naproxen, and aspirin. |
| T461 |
230-408 |
Sentence |
denotes |
Given the widespread use of these medications it is appropriate that researchers have investigated the potential benefits and harms of NSAIDs in patients diagnosed with COVID-19. |
| T462 |
409-573 |
Sentence |
denotes |
Thus far, the evidence for using NSAIDs in the context of CoVs are mixed and might not be generalizable to all NSAIDs as reports tended to focus on specific NSAIDs. |
| T463 |
574-729 |
Sentence |
denotes |
These studies also focused on the potential for NSAIDs to act as an antiviral, with a potential added benefit of being able to treat inflammatory symptoms. |
| T464 |
730-877 |
Sentence |
denotes |
One report showed that the NSAID indomethacin could directly inhibit SARS-CoV replication in Vero cell monolayers in a dose-dependent manner (263). |
| T465 |
878-1146 |
Sentence |
denotes |
The antiviral properties of naproxen have been described in the context of influenza virus (264, 265) and has prompted the initiation of a clinical trial investigating the efficacy of naproxen as a treatment for critically ill COVID-19 infected patients (NCT04325633). |
