| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T44 |
0-121 |
Sentence |
denotes |
Like SARS-CoV-1 and MERS-CoV, SARS-CoV-2 is thought to have originated in bats through an unknown intermediary host (43). |
| T45 |
122-273 |
Sentence |
denotes |
At the time of writing, the number of global infections is estimated to be over 5,000,000 with over 340,000 deaths (44) and the R0 is roughly 2.2 (45). |
| T46 |
274-472 |
Sentence |
denotes |
Like other diseases caused by infectious CoVs, most patients present with flu-like symptoms including fever, cough, and lethargy, with the development of pneumonia and ARDS often proving fatal (46). |
| T47 |
473-634 |
Sentence |
denotes |
Furthermore, patients with underlying conditions are at risk for further complications if infected with COVID-19, such as those with cardiovascular disease (47). |
| T48 |
635-755 |
Sentence |
denotes |
SARS-CoV-2 has been posthumously detected in not only the lungs, but the pharynx, heart, liver, brain, and kidneys (48). |
| T49 |
756-999 |
Sentence |
denotes |
Transmission of SARS-CoV-2 is thought to mainly occur through direct contact/inhalation of respiratory droplets and aerosols from infected carriers, but indirect transmission by fomites has also been reported, although less efficient (49, 50). |
| T50 |
1000-1152 |
Sentence |
denotes |
SARS-CoV-2 viral entrance is thought to be mediated by binding of the S protein to the ACE2 receptor (51, 52), although this is still under debate (53). |
| T51 |
1153-1366 |
Sentence |
denotes |
While direct cytopathic effects are thought to play a major role in CoV pathology, studies have suggested that a dysregulated immune response resulting in pathological inflammation is also partly responsible (19). |
| T52 |
1367-1546 |
Sentence |
denotes |
With the current pandemic already surpassing the previous CoV outbreaks (54), rapid deployment of novel approaches to understanding and treating coronavirus infections are needed. |
