PMC:7212965 / 39135-39809 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T244 0-10 Sentence denotes Remdesivir
T245 11-104 Sentence denotes Limited data regarding GI adverse events are available, as phase 3 trials are still underway.
T246 105-428 Sentence denotes Based on studies regarding Ebola, there have been reports of elevated transaminases, although the severity and incidence have not been quantified.87 There is 1 published case series (n = 53) on compassionate use of remdesivir in COVID-19.88 In this study, the most common adverse effects were notably Gl and hepatotoxicity.
T247 429-573 Sentence denotes Five of 53 patients (9%) experienced diarrhea and 12 of 53 patients (23%) had reported elevations in hepatic enzymes associated with remdesivir.
T248 574-674 Sentence denotes Of 4 patients (8%) who discontinued treatment prematurely, 2 were due to elevated aminotransferases.