PMC:7161517 / 29803-30611 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T182 0-336 Sentence denotes If SARS-CoV-2 does induce ACE2 ectodomain shedding, which results in the reduction of ACE2 entry sites on the infected cell, it is possible that following transcription S proteins fuse directly at the host cell membrane and directly promote infection of neighboring cells, which results in the formation of multinucleated syncytia (66).
T183 337-475 Sentence denotes Formation of multinucleated cells would allow the virus to spread without being detected or neutralized by virus-specific antibodies (66).
T184 476-653 Sentence denotes Otherwise, following replication and transcription, complete virion assembly in the Golgi would result in transportation of the virus in vesicles and release by exocytosis (66).
T185 654-808 Sentence denotes In the setting of full virion assembly and exocytosis, it is unclear if ACE2 ectodomain shedding would be favorable for further propagation and infection.