PMC:7074424 / 27259-27995 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T160 0-40 Sentence denotes Other Strategies to Counter Coronavirus:
T161 41-53 Sentence denotes Endosomal pH
T162 54-310 Sentence denotes Once entered into the host cell, the subsequent life cycle of SERS-CoV requires low pH.[90] Inhibitors of pH-sensitive endosomal protease block CoV infection.[9091] Several different small compounds and molecules have been reported against virus infection.
T163 311-364 Sentence denotes Amiodarone gets accumulated in the acidic organelles.
T164 365-486 Sentence denotes Vacuoles on exposure to amiodarone shows alteration in intracellular organelles especially enlargement of late endosomes.
T165 487-657 Sentence denotes In in-vitro environment, amiodarone inhibited coronavirus infection in Vero cells.[92] At priori trypsin, cleavage of S protein is essential for a successful viral entry.
T166 658-736 Sentence denotes However, trypsin cleavage also does not affect the efficacy of amiodarone.[92]