Id |
Subject |
Object |
Predicate |
Lexical cue |
T160 |
0-40 |
Sentence |
denotes |
Other Strategies to Counter Coronavirus: |
T161 |
41-53 |
Sentence |
denotes |
Endosomal pH |
T162 |
54-310 |
Sentence |
denotes |
Once entered into the host cell, the subsequent life cycle of SERS-CoV requires low pH.[90] Inhibitors of pH-sensitive endosomal protease block CoV infection.[9091] Several different small compounds and molecules have been reported against virus infection. |
T163 |
311-364 |
Sentence |
denotes |
Amiodarone gets accumulated in the acidic organelles. |
T164 |
365-486 |
Sentence |
denotes |
Vacuoles on exposure to amiodarone shows alteration in intracellular organelles especially enlargement of late endosomes. |
T165 |
487-657 |
Sentence |
denotes |
In in-vitro environment, amiodarone inhibited coronavirus infection in Vero cells.[92] At priori trypsin, cleavage of S protein is essential for a successful viral entry. |
T166 |
658-736 |
Sentence |
denotes |
However, trypsin cleavage also does not affect the efficacy of amiodarone.[92] |