| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T224 |
0-12 |
NN |
denotes |
Introduction |
| T225 |
13-26 |
NNS |
denotes |
Coronaviruses |
| T226 |
27-28 |
-LRB- |
denotes |
( |
| T227 |
28-32 |
NNS |
denotes |
CoVs |
| T228 |
32-33 |
-RRB- |
denotes |
) |
| T229 |
34-37 |
VBP |
denotes |
are |
| T230 |
38-47 |
VBN |
denotes |
enveloped |
| T231 |
48-57 |
NNS |
denotes |
pathogens |
| T232 |
58-69 |
JJ |
denotes |
responsible |
| T233 |
70-73 |
IN |
denotes |
for |
| T234 |
74-82 |
JJ |
denotes |
multiple |
| T235 |
83-94 |
JJ |
denotes |
respiratory |
| T236 |
95-104 |
NNS |
denotes |
disorders |
| T237 |
105-107 |
IN |
denotes |
of |
| T238 |
108-115 |
VBG |
denotes |
varying |
| T239 |
116-124 |
NN |
denotes |
severity |
| T240 |
125-127 |
IN |
denotes |
in |
| T241 |
128-135 |
NN |
denotes |
humans1 |
| T242 |
137-144 |
JJ |
denotes |
Certain |
| T243 |
145-149 |
NNS |
denotes |
CoVs |
| T244 |
150-159 |
VBP |
denotes |
represent |
| T245 |
160-161 |
DT |
denotes |
a |
| T246 |
162-173 |
JJ |
denotes |
significant |
| T247 |
174-180 |
NN |
denotes |
threat |
| T248 |
181-183 |
TO |
denotes |
to |
| T249 |
184-190 |
JJ |
denotes |
global |
| T250 |
191-196 |
JJ |
denotes |
human |
| T251 |
197-203 |
NN |
denotes |
health |
| T252 |
203-204 |
-COMMA- |
denotes |
, |
| T253 |
205-207 |
IN |
denotes |
as |
| T254 |
208-219 |
VBN |
denotes |
illustrated |
| T255 |
220-222 |
IN |
denotes |
by |
| T256 |
223-232 |
NNS |
denotes |
outbreaks |
| T257 |
233-235 |
IN |
denotes |
of |
| T258 |
236-242 |
JJ |
denotes |
severe |
| T259 |
243-248 |
JJ |
denotes |
acute |
| T260 |
249-260 |
JJ |
denotes |
respiratory |
| T261 |
261-269 |
NN |
denotes |
syndrome |
| T262 |
270-281 |
NN |
denotes |
coronavirus |
| T263 |
282-283 |
-LRB- |
denotes |
( |
| T264 |
283-291 |
NN |
denotes |
SARS-CoV |
| T265 |
291-292 |
-RRB- |
denotes |
) |
| T266 |
293-295 |
IN |
denotes |
in |
| T267 |
296-301 |
CD |
denotes |
20032 |
| T268 |
301-302 |
-COMMA- |
denotes |
, |
| T269 |
303-309 |
NNP |
denotes |
Middle |
| T270 |
310-314 |
NNP |
denotes |
East |
| T271 |
315-326 |
JJ |
denotes |
respiratory |
| T272 |
327-335 |
NN |
denotes |
syndrome |
| T273 |
336-347 |
NN |
denotes |
coronavirus |
| T274 |
348-349 |
-LRB- |
denotes |
( |
| T275 |
349-357 |
NN |
denotes |
MERS-CoV |
| T276 |
357-358 |
-RRB- |
denotes |
) |
| T277 |
359-361 |
IN |
denotes |
in |
| T278 |
362-367 |
CD |
denotes |
20123 |
| T279 |
367-368 |
-COMMA- |
denotes |
, |
| T280 |
369-372 |
CC |
denotes |
and |
| T281 |
373-377 |
RBS |
denotes |
most |
| T282 |
378-386 |
RB |
denotes |
recently |
| T283 |
387-389 |
IN |
denotes |
of |
| T284 |
390-401 |
NN |
denotes |
SARS-CoV-24 |
| T285 |
403-408 |
VBN |
denotes |
Given |
| T286 |
409-414 |
PRP-DOLLAR- |
denotes |
their |
| T287 |
415-424 |
NN |
denotes |
mortality |
| T288 |
425-430 |
NNS |
denotes |
rates |
| T289 |
430-431 |
-COMMA- |
denotes |
, |
| T290 |
432-435 |
DT |
denotes |
the |
| T291 |
436-443 |
JJ |
denotes |
current |
| T292 |
444-448 |
NN |
denotes |
lack |
| T293 |
449-451 |
IN |
denotes |
of |
| T294 |
452-460 |
VBN |
denotes |
targeted |
| T295 |
461-471 |
NNS |
denotes |
treatments |
| T296 |
472-475 |
CC |
denotes |
and |
| T297 |
476-484 |
JJ |
denotes |
licensed |
| T298 |
485-493 |
NNS |
denotes |
vaccines |
| T299 |
493-494 |
-COMMA- |
denotes |
, |
| T300 |
495-498 |
CC |
denotes |
and |
| T301 |
499-504 |
PRP-DOLLAR- |
denotes |
their |
| T302 |
505-513 |
NN |
denotes |
capacity |
| T303 |
514-516 |
TO |
denotes |
to |
| T304 |
517-525 |
VB |
denotes |
transmit |
| T305 |
526-533 |
IN |
denotes |
between |
| T306 |
534-540 |
NNS |
denotes |
humans |
| T307 |
541-544 |
CC |
denotes |
and |
| T308 |
545-551 |
IN |
denotes |
across |
| T309 |
552-559 |
NNS |
denotes |
species |
| T310 |
560-571 |
NN |
denotes |
barriers5,6 |
| T311 |
571-572 |
-COMMA- |
denotes |
, |
| T312 |
573-578 |
EX |
denotes |
there |
| T313 |
579-581 |
VBZ |
denotes |
is |
| T314 |
582-584 |
DT |
denotes |
an |
| T315 |
585-591 |
JJ |
denotes |
urgent |
| T316 |
592-596 |
NN |
denotes |
need |
| T317 |
597-600 |
IN |
denotes |
for |
| T318 |
601-610 |
JJ |
denotes |
effective |
| T319 |
611-626 |
NNS |
denotes |
countermeasures |
| T320 |
627-629 |
TO |
denotes |
to |
| T321 |
630-636 |
VB |
denotes |
combat |
| T322 |
637-642 |
DT |
denotes |
these |
| T323 |
643-652 |
NNS |
denotes |
pathogens |
| T324 |
654-661 |
VBG |
denotes |
Ongoing |
| T325 |
662-669 |
NN |
denotes |
vaccine |
| T326 |
670-681 |
NN |
denotes |
development |
| T327 |
682-689 |
NNS |
denotes |
efforts |
| T328 |
690-695 |
NN |
denotes |
focus |
| T329 |
696-698 |
IN |
denotes |
on |
| T330 |
699-702 |
DT |
denotes |
the |
| T331 |
703-708 |
NN |
denotes |
spike |
| T332 |
709-710 |
-LRB- |
denotes |
( |
| T333 |
710-711 |
NN |
denotes |
S |
| T334 |
711-712 |
-RRB- |
denotes |
) |
| T335 |
713-721 |
NNS |
denotes |
proteins |
| T336 |
722-726 |
WDT |
denotes |
that |
| T337 |
727-735 |
VBP |
denotes |
protrude |
| T338 |
736-740 |
IN |
denotes |
from |
| T339 |
741-744 |
DT |
denotes |
the |
| T340 |
745-750 |
JJ |
denotes |
viral |
| T341 |
751-759 |
NN |
denotes |
envelope |
| T342 |
760-763 |
CC |
denotes |
and |
| T343 |
764-774 |
VB |
denotes |
constitute |
| T344 |
775-778 |
DT |
denotes |
the |
| T345 |
779-783 |
JJ |
denotes |
main |
| T346 |
784-790 |
NN |
denotes |
target |
| T347 |
791-793 |
IN |
denotes |
of |
| T348 |
794-806 |
VBG |
denotes |
neutralizing |
| T349 |
807-820 |
NN |
denotes |
antibodies7,8 |
| T350 |
822-827 |
DT |
denotes |
These |
| T351 |
828-836 |
JJ |
denotes |
trimeric |
| T352 |
837-838 |
NN |
denotes |
S |
| T353 |
839-847 |
NNS |
denotes |
proteins |
| T354 |
848-855 |
VBP |
denotes |
mediate |
| T355 |
856-865 |
JJ |
denotes |
host-cell |
| T356 |
866-871 |
NN |
denotes |
entry |
| T357 |
872-876 |
IN |
denotes |
with |
| T358 |
877-880 |
DT |
denotes |
the |
| T359 |
881-883 |
NN |
denotes |
S1 |
| T360 |
884-887 |
CC |
denotes |
and |
| T361 |
888-890 |
NN |
denotes |
S2 |
| T362 |
891-899 |
NNS |
denotes |
subunits |
| T363 |
900-911 |
JJ |
denotes |
responsible |
| T364 |
912-915 |
IN |
denotes |
for |
| T365 |
916-923 |
VBG |
denotes |
binding |
| T366 |
924-926 |
TO |
denotes |
to |
| T367 |
927-930 |
DT |
denotes |
the |
| T368 |
931-940 |
NN |
denotes |
host-cell |
| T369 |
941-949 |
NN |
denotes |
receptor |
| T370 |
950-953 |
CC |
denotes |
and |
| T371 |
954-966 |
VBG |
denotes |
facilitating |
| T372 |
967-975 |
NN |
denotes |
membrane |
| T373 |
976-982 |
NN |
denotes |
fusion |
| T374 |
982-983 |
-COMMA- |
denotes |
, |
| T375 |
984-1000 |
NN |
denotes |
respectively9–11 |
| T376 |
1002-1006 |
NNS |
denotes |
MERS |
| T377 |
1007-1008 |
NN |
denotes |
S |
| T378 |
1009-1014 |
VBZ |
denotes |
binds |
| T379 |
1015-1017 |
TO |
denotes |
to |
| T380 |
1018-1038 |
NN |
denotes |
dipeptidyl-peptidase |
| T381 |
1039-1040 |
CD |
denotes |
4 |
| T382 |
1041-1042 |
-LRB- |
denotes |
( |
| T383 |
1042-1046 |
NN |
denotes |
DPP4 |
| T384 |
1046-1047 |
-RRB- |
denotes |
) |
| T385 |
1047-1049 |
CD |
denotes |
12 |
| T386 |
1049-1050 |
-COMMA- |
denotes |
, |
| T387 |
1051-1058 |
IN |
denotes |
whereas |
| T388 |
1059-1063 |
NN |
denotes |
SARS |
| T389 |
1064-1067 |
NN |
denotes |
S13 |
| T390 |
1068-1071 |
CC |
denotes |
and |
| T391 |
1072-1087 |
NN |
denotes |
SARS-CoV-214,15 |
| T392 |
1088-1095 |
VBP |
denotes |
utilize |
| T393 |
1096-1118 |
JJ |
denotes |
angiotensin-converting |
| T394 |
1119-1125 |
NN |
denotes |
enzyme |
| T395 |
1126-1127 |
CD |
denotes |
2 |
| T396 |
1128-1129 |
-LRB- |
denotes |
( |
| T397 |
1129-1133 |
NN |
denotes |
ACE2 |
| T398 |
1133-1134 |
-RRB- |
denotes |
) |
| T399 |
1135-1137 |
IN |
denotes |
as |
| T400 |
1138-1139 |
DT |
denotes |
a |
| T401 |
1140-1144 |
NN |
denotes |
host |
| T402 |
1145-1153 |
JJ |
denotes |
cellular |
| T403 |
1154-1162 |
NN |
denotes |
receptor |
| T404 |
1164-1167 |
NN |
denotes |
CoV |
| T405 |
1168-1169 |
NN |
denotes |
S |
| T406 |
1170-1178 |
NNS |
denotes |
proteins |
| T407 |
1179-1182 |
VBP |
denotes |
are |
| T408 |
1183-1186 |
DT |
denotes |
the |
| T409 |
1187-1194 |
JJS |
denotes |
largest |
| T410 |
1195-1200 |
NN |
denotes |
class |
| T411 |
1201-1202 |
CD |
denotes |
I |
| T412 |
1203-1208 |
JJ |
denotes |
viral |
| T413 |
1209-1215 |
NN |
denotes |
fusion |
| T414 |
1216-1224 |
NNS |
denotes |
proteins |
| T415 |
1225-1231 |
NN |
denotes |
known9 |
| T416 |
1231-1232 |
-COMMA- |
denotes |
, |
| T417 |
1233-1236 |
CC |
denotes |
and |
| T418 |
1237-1240 |
VBP |
denotes |
are |
| T419 |
1241-1252 |
RB |
denotes |
extensively |
| T420 |
1253-1265 |
VBN |
denotes |
glycosylated |
| T421 |
1265-1266 |
-COMMA- |
denotes |
, |
| T422 |
1267-1271 |
IN |
denotes |
with |
| T423 |
1272-1276 |
NNP |
denotes |
SARS |
| T424 |
1277-1280 |
CC |
denotes |
and |
| T425 |
1281-1285 |
NNP |
denotes |
MERS |
| T426 |
1286-1287 |
NN |
denotes |
S |
| T427 |
1288-1301 |
NNS |
denotes |
glycoproteins |
| T428 |
1302-1306 |
CC |
denotes |
both |
| T429 |
1307-1315 |
VBG |
denotes |
encoding |
| T430 |
1316-1318 |
CD |
denotes |
69 |
| T431 |
1319-1327 |
JJ |
denotes |
N-linked |
| T432 |
1328-1334 |
NN |
denotes |
glycan |
| T433 |
1335-1342 |
NNS |
denotes |
sequons |
| T434 |
1343-1346 |
IN |
denotes |
per |
| T435 |
1347-1355 |
JJ |
denotes |
trimeric |
| T436 |
1356-1361 |
NN |
denotes |
spike |
| T437 |
1362-1366 |
IN |
denotes |
with |
| T438 |
1367-1377 |
NN |
denotes |
SARS-CoV-2 |
| T439 |
1378-1388 |
VBG |
denotes |
containing |
| T440 |
1389-1391 |
CD |
denotes |
66 |
| T441 |
1392-1397 |
NNS |
denotes |
sites |
| T442 |
1399-1404 |
DT |
denotes |
These |
| T443 |
1405-1418 |
NNS |
denotes |
modifications |
| T444 |
1419-1424 |
RB |
denotes |
often |
| T445 |
1425-1429 |
VBP |
denotes |
mask |
| T446 |
1430-1441 |
JJ |
denotes |
immunogenic |
| T447 |
1442-1449 |
NN |
denotes |
protein |
| T448 |
1450-1458 |
NNS |
denotes |
epitopes |
| T449 |
1459-1463 |
IN |
denotes |
from |
| T450 |
1464-1467 |
DT |
denotes |
the |
| T451 |
1468-1472 |
NN |
denotes |
host |
| T452 |
1473-1480 |
JJ |
denotes |
humoral |
| T453 |
1481-1487 |
JJ |
denotes |
immune |
| T454 |
1488-1494 |
NN |
denotes |
system |
| T455 |
1495-1497 |
IN |
denotes |
by |
| T456 |
1498-1507 |
VBG |
denotes |
occluding |
| T457 |
1508-1512 |
PRP |
denotes |
them |
| T458 |
1513-1517 |
IN |
denotes |
with |
| T459 |
1518-1530 |
JJ |
denotes |
host-derived |
| T460 |
1531-1543 |
NN |
denotes |
glycans16–18 |
| T461 |
1545-1549 |
DT |
denotes |
This |
| T462 |
1550-1560 |
NN |
denotes |
phenomenon |
| T463 |
1561-1563 |
IN |
denotes |
of |
| T464 |
1564-1570 |
JJ |
denotes |
immune |
| T465 |
1571-1578 |
NN |
denotes |
evasion |
| T466 |
1579-1581 |
IN |
denotes |
by |
| T467 |
1582-1591 |
JJ |
denotes |
molecular |
| T468 |
1592-1599 |
NN |
denotes |
mimicry |
| T469 |
1600-1603 |
CC |
denotes |
and |
| T470 |
1604-1610 |
NN |
denotes |
glycan |
| T471 |
1611-1620 |
NN |
denotes |
shielding |
| T472 |
1621-1624 |
VBZ |
denotes |
has |
| T473 |
1625-1629 |
VBN |
denotes |
been |
| T474 |
1630-1634 |
RB |
denotes |
well |
| T475 |
1635-1648 |
VBN |
denotes |
characterised |
| T476 |
1649-1655 |
IN |
denotes |
across |
| T477 |
1656-1661 |
JJ |
denotes |
other |
| T478 |
1662-1667 |
JJ |
denotes |
viral |
| T479 |
1668-1681 |
NNS |
denotes |
glycoproteins |
| T480 |
1681-1682 |
-COMMA- |
denotes |
, |
| T481 |
1683-1687 |
JJ |
denotes |
such |
| T482 |
1688-1690 |
IN |
denotes |
as |
| T483 |
1691-1696 |
NN |
denotes |
HIV-1 |
| T484 |
1697-1705 |
NN |
denotes |
envelope |
| T485 |
1706-1713 |
NN |
denotes |
protein |
| T486 |
1714-1715 |
-LRB- |
denotes |
( |
| T487 |
1715-1718 |
NN |
denotes |
Env |
| T488 |
1718-1719 |
-RRB- |
denotes |
) |
| T489 |
1719-1724 |
CD |
denotes |
19–21 |
| T490 |
1724-1725 |
-COMMA- |
denotes |
, |
| T491 |
1726-1735 |
NN |
denotes |
influenza |
| T492 |
1736-1749 |
NN |
denotes |
hemagglutinin |
| T493 |
1750-1751 |
-LRB- |
denotes |
( |
| T494 |
1751-1753 |
NN |
denotes |
HA |
| T495 |
1753-1754 |
-RRB- |
denotes |
) |
| T496 |
1754-1759 |
CD |
denotes |
22,23 |
| T497 |
1760-1763 |
CC |
denotes |
and |
| T498 |
1764-1769 |
NNP |
denotes |
Lassa |
| T499 |
1770-1775 |
NN |
denotes |
virus |
| T500 |
1776-1788 |
NN |
denotes |
glycoprotein |
| T501 |
1789-1796 |
NN |
denotes |
complex |
| T502 |
1797-1798 |
-LRB- |
denotes |
( |
| T503 |
1798-1802 |
NN |
denotes |
LASV |
| T504 |
1803-1806 |
NN |
denotes |
GPC |
| T505 |
1806-1807 |
-RRB- |
denotes |
) |
| T506 |
1807-1812 |
CD |
denotes |
24–26 |
| T507 |
1814-1822 |
JJ |
denotes |
Previous |
| T508 |
1823-1831 |
NNS |
denotes |
analyses |
| T509 |
1832-1834 |
IN |
denotes |
of |
| T510 |
1835-1840 |
JJ |
denotes |
viral |
| T511 |
1841-1847 |
NN |
denotes |
glycan |
| T512 |
1848-1855 |
NNS |
denotes |
shields |
| T513 |
1856-1860 |
VBP |
denotes |
have |
| T514 |
1861-1869 |
VBN |
denotes |
revealed |
| T515 |
1870-1873 |
DT |
denotes |
the |
| T516 |
1874-1882 |
NN |
denotes |
presence |
| T517 |
1883-1885 |
IN |
denotes |
of |
| T518 |
1886-1900 |
JJ |
denotes |
underprocessed |
| T519 |
1901-1918 |
JJ |
denotes |
oligomannose-type |
| T520 |
1919-1926 |
NNS |
denotes |
glycans |
| T521 |
1927-1931 |
WDT |
denotes |
that |
| T522 |
1932-1941 |
RB |
denotes |
seemingly |
| T523 |
1942-1947 |
VBP |
denotes |
arise |
| T524 |
1948-1951 |
JJ |
denotes |
due |
| T525 |
1952-1954 |
TO |
denotes |
to |
| T526 |
1955-1961 |
JJ |
denotes |
steric |
| T527 |
1962-1973 |
NNS |
denotes |
constraints |
| T528 |
1974-1978 |
WDT |
denotes |
that |
| T529 |
1979-1986 |
VBP |
denotes |
prevent |
| T530 |
1987-1993 |
NN |
denotes |
access |
| T531 |
1994-1996 |
IN |
denotes |
of |
| T532 |
1997-2003 |
NN |
denotes |
glycan |
| T533 |
2004-2014 |
NN |
denotes |
processing |
| T534 |
2015-2022 |
NNS |
denotes |
enzymes |
| T535 |
2023-2025 |
TO |
denotes |
to |
| T536 |
2026-2035 |
NN |
denotes |
substrate |
| T537 |
2036-2051 |
NN |
denotes |
glycans24,27,28 |
| T538 |
2051-2052 |
-COMMA- |
denotes |
, |
| T539 |
2053-2063 |
RB |
denotes |
especially |
| T540 |
2064-2068 |
WRB |
denotes |
when |
| T541 |
2069-2072 |
DT |
denotes |
the |
| T542 |
2073-2078 |
JJ |
denotes |
viral |
| T543 |
2079-2091 |
NN |
denotes |
glycoprotein |
| T544 |
2092-2095 |
VBZ |
denotes |
has |
| T545 |
2096-2103 |
VBN |
denotes |
evolved |
| T546 |
2104-2106 |
TO |
denotes |
to |
| T547 |
2107-2111 |
VB |
denotes |
mask |
| T548 |
2112-2123 |
JJ |
denotes |
immunogenic |
| T549 |
2124-2132 |
NNS |
denotes |
epitopes |
| T550 |
2133-2137 |
IN |
denotes |
with |
| T551 |
2138-2139 |
DT |
denotes |
a |
| T552 |
2140-2152 |
RB |
denotes |
particularly |
| T553 |
2153-2158 |
JJ |
denotes |
dense |
| T554 |
2159-2164 |
NN |
denotes |
array |
| T555 |
2165-2167 |
IN |
denotes |
of |
| T556 |
2168-2180 |
JJ |
denotes |
host-derived |
| T557 |
2181-2196 |
NN |
denotes |
glycans26,29–34 |
| T558 |
2198-2208 |
JJ |
denotes |
Restricted |
| T559 |
2209-2215 |
NN |
denotes |
access |
| T560 |
2216-2218 |
TO |
denotes |
to |
| T561 |
2219-2224 |
DT |
denotes |
these |
| T562 |
2225-2231 |
NN |
denotes |
glycan |
| T563 |
2232-2237 |
NNS |
denotes |
sites |
| T564 |
2238-2240 |
CC |
denotes |
or |
| T565 |
2241-2253 |
NN |
denotes |
interference |
| T566 |
2254-2258 |
IN |
denotes |
with |
| T567 |
2259-2270 |
VBG |
denotes |
surrounding |
| T568 |
2271-2278 |
NN |
denotes |
protein |
| T569 |
2279-2286 |
NN |
denotes |
surface |
| T570 |
2287-2289 |
CC |
denotes |
or |
| T571 |
2290-2302 |
VBG |
denotes |
neighbouring |
| T572 |
2303-2309 |
NN |
denotes |
glycan |
| T573 |
2310-2318 |
NNS |
denotes |
residues |
| T574 |
2319-2322 |
MD |
denotes |
can |
| T575 |
2323-2329 |
VB |
denotes |
render |
| T576 |
2330-2336 |
NN |
denotes |
glycan |
| T577 |
2337-2347 |
NN |
denotes |
processing |
| T578 |
2348-2355 |
NNS |
denotes |
enzymes |
| T579 |
2356-2367 |
JJ |
denotes |
ineffective |
| T580 |
2368-2370 |
IN |
denotes |
in |
| T581 |
2371-2379 |
JJ |
denotes |
specific |
| T582 |
2380-2395 |
NN |
denotes |
regions27,28,35 |
| T583 |
2397-2403 |
NN |
denotes |
Glycan |
| T584 |
2404-2414 |
NN |
denotes |
processing |
| T585 |
2415-2417 |
IN |
denotes |
on |
| T586 |
2418-2425 |
JJ |
denotes |
soluble |
| T587 |
2426-2439 |
NNS |
denotes |
glycoproteins |
| T588 |
2440-2443 |
VBZ |
denotes |
has |
| T589 |
2444-2448 |
RB |
denotes |
also |
| T590 |
2449-2453 |
VBN |
denotes |
been |
| T591 |
2454-2459 |
VBN |
denotes |
shown |
| T592 |
2460-2462 |
TO |
denotes |
to |
| T593 |
2463-2465 |
VB |
denotes |
be |
| T594 |
2466-2467 |
DT |
denotes |
a |
| T595 |
2468-2474 |
JJ |
denotes |
strong |
| T596 |
2475-2483 |
NN |
denotes |
reporter |
| T597 |
2484-2486 |
IN |
denotes |
of |
| T598 |
2487-2498 |
JJ |
denotes |
native-like |
| T599 |
2499-2506 |
NN |
denotes |
protein |
| T600 |
2507-2519 |
NN |
denotes |
architecture |
| T601 |
2520-2523 |
CC |
denotes |
and |
| T602 |
2524-2528 |
RB |
denotes |
thus |
| T603 |
2529-2538 |
NN |
denotes |
immunogen |
| T604 |
2539-2553 |
NN |
denotes |
integrity36–38 |
| T605 |
2553-2554 |
-SEMICOLON- |
denotes |
; |
| T606 |
2555-2558 |
CC |
denotes |
and |
| T607 |
2559-2565 |
NN |
denotes |
glycan |
| T608 |
2566-2576 |
NN |
denotes |
processing |
| T609 |
2577-2579 |
IN |
denotes |
on |
| T610 |
2580-2581 |
DT |
denotes |
a |
| T611 |
2582-2592 |
JJ |
denotes |
successful |
| T612 |
2593-2602 |
NN |
denotes |
immunogen |
| T613 |
2603-2612 |
NN |
denotes |
candidate |
| T614 |
2613-2619 |
MD |
denotes |
should |
| T615 |
2620-2629 |
RB |
denotes |
therefore |
| T616 |
2630-2635 |
VB |
denotes |
mimic |
| T617 |
2635-2636 |
-COMMA- |
denotes |
, |
| T618 |
2637-2639 |
RB |
denotes |
as |
| T619 |
2640-2647 |
RB |
denotes |
closely |
| T620 |
2648-2650 |
IN |
denotes |
as |
| T621 |
2651-2659 |
JJ |
denotes |
possible |
| T622 |
2659-2660 |
-COMMA- |
denotes |
, |
| T623 |
2661-2664 |
DT |
denotes |
the |
| T624 |
2665-2675 |
JJ |
denotes |
structural |
| T625 |
2676-2684 |
NNS |
denotes |
features |
| T626 |
2685-2693 |
VBN |
denotes |
observed |
| T627 |
2694-2696 |
IN |
denotes |
on |
| T628 |
2697-2700 |
DT |
denotes |
the |
| T629 |
2701-2707 |
JJ |
denotes |
native |
| T630 |
2708-2718 |
NN |
denotes |
virus39,40 |
| T631 |
2720-2724 |
RB |
denotes |
Here |
| T632 |
2724-2725 |
-COMMA- |
denotes |
, |
| T633 |
2726-2728 |
PRP |
denotes |
we |
| T634 |
2729-2736 |
VBP |
denotes |
provide |
| T635 |
2737-2743 |
JJ |
denotes |
global |
| T636 |
2744-2747 |
CC |
denotes |
and |
| T637 |
2748-2761 |
JJ |
denotes |
site-specific |
| T638 |
2762-2770 |
NNS |
denotes |
analyses |
| T639 |
2771-2773 |
IN |
denotes |
of |
| T640 |
2774-2782 |
JJ |
denotes |
N-linked |
| T641 |
2783-2796 |
NN |
denotes |
glycosylation |
| T642 |
2797-2799 |
IN |
denotes |
on |
| T643 |
2800-2807 |
JJ |
denotes |
soluble |
| T644 |
2808-2812 |
NNS |
denotes |
SARS |
| T645 |
2812-2813 |
-COMMA- |
denotes |
, |
| T646 |
2814-2818 |
NNS |
denotes |
MERS |
| T647 |
2819-2822 |
CC |
denotes |
and |
| T648 |
2823-2827 |
NN |
denotes |
HKU1 |
| T649 |
2828-2831 |
NN |
denotes |
CoV |
| T650 |
2832-2833 |
NN |
denotes |
S |
| T651 |
2834-2847 |
NNS |
denotes |
glycoproteins |
| T652 |
2848-2851 |
CC |
denotes |
and |
| T653 |
2852-2858 |
VB |
denotes |
reveal |
| T654 |
2859-2868 |
JJ |
denotes |
extensive |
| T655 |
2869-2882 |
NN |
denotes |
heterogeneity |
| T656 |
2882-2883 |
-COMMA- |
denotes |
, |
| T657 |
2884-2891 |
VBG |
denotes |
ranging |
| T658 |
2892-2896 |
IN |
denotes |
from |
| T659 |
2897-2914 |
JJ |
denotes |
oligomannose-type |
| T660 |
2915-2922 |
NNS |
denotes |
glycans |
| T661 |
2923-2925 |
TO |
denotes |
to |
| T662 |
2926-2942 |
JJ |
denotes |
highly-processed |
| T663 |
2943-2955 |
JJ |
denotes |
complex-type |
| T664 |
2956-2969 |
NN |
denotes |
glycosylation |
| T665 |
2971-2974 |
DT |
denotes |
The |
| T666 |
2975-2985 |
JJ |
denotes |
structural |
| T667 |
2986-2993 |
NN |
denotes |
mapping |
| T668 |
2994-2996 |
IN |
denotes |
of |
| T669 |
2997-3004 |
NNS |
denotes |
glycans |
| T670 |
3005-3007 |
IN |
denotes |
of |
| T671 |
3008-3016 |
JJ |
denotes |
trimeric |
| T672 |
3017-3018 |
NN |
denotes |
S |
| T673 |
3019-3027 |
NNS |
denotes |
proteins |
| T674 |
3028-3036 |
VBD |
denotes |
revealed |
| T675 |
3037-3041 |
IN |
denotes |
that |
| T676 |
3042-3046 |
DT |
denotes |
some |
| T677 |
3047-3049 |
IN |
denotes |
of |
| T678 |
3050-3055 |
DT |
denotes |
these |
| T679 |
3056-3063 |
NNS |
denotes |
glycans |
| T680 |
3064-3074 |
VBP |
denotes |
contribute |
| T681 |
3075-3077 |
TO |
denotes |
to |
| T682 |
3078-3081 |
DT |
denotes |
the |
| T683 |
3082-3091 |
NN |
denotes |
formation |
| T684 |
3092-3094 |
IN |
denotes |
of |
| T685 |
3095-3096 |
DT |
denotes |
a |
| T686 |
3097-3104 |
NN |
denotes |
cluster |
| T687 |
3105-3107 |
IN |
denotes |
of |
| T688 |
3108-3125 |
JJ |
denotes |
oligomannose-type |
| T689 |
3126-3133 |
NNS |
denotes |
glycans |
| T690 |
3134-3136 |
IN |
denotes |
at |
| T691 |
3137-3145 |
JJ |
denotes |
specific |
| T692 |
3146-3153 |
NNS |
denotes |
regions |
| T693 |
3154-3156 |
IN |
denotes |
of |
| T694 |
3157-3161 |
JJ |
denotes |
high |
| T695 |
3162-3168 |
NN |
denotes |
glycan |
| T696 |
3169-3176 |
NN |
denotes |
density |
| T697 |
3177-3179 |
IN |
denotes |
on |
| T698 |
3180-3188 |
NNP |
denotes |
MERS-CoV |
| T699 |
3189-3191 |
NNP |
denotes |
S. |
| T700 |
3192-3201 |
NNP |
denotes |
Molecular |
| T701 |
3202-3211 |
NN |
denotes |
evolution |
| T702 |
3212-3220 |
NN |
denotes |
analysis |
| T703 |
3221-3223 |
IN |
denotes |
of |
| T704 |
3224-3228 |
NNP |
denotes |
SARS |
| T705 |
3229-3232 |
CC |
denotes |
and |
| T706 |
3233-3237 |
NNP |
denotes |
MERS |
| T707 |
3238-3239 |
NN |
denotes |
S |
| T708 |
3240-3245 |
NNS |
denotes |
genes |
| T709 |
3246-3250 |
RB |
denotes |
also |
| T710 |
3251-3258 |
VBZ |
denotes |
reveals |
| T711 |
3259-3260 |
DT |
denotes |
a |
| T712 |
3261-3267 |
JJR |
denotes |
higher |
| T713 |
3268-3277 |
NN |
denotes |
incidence |
| T714 |
3278-3280 |
IN |
denotes |
of |
| T715 |
3281-3291 |
JJ |
denotes |
amino-acid |
| T716 |
3292-3301 |
NN |
denotes |
diversity |
| T717 |
3302-3304 |
IN |
denotes |
on |
| T718 |
3305-3308 |
DT |
denotes |
the |
| T719 |
3309-3316 |
VBN |
denotes |
exposed |
| T720 |
3317-3325 |
NNS |
denotes |
surfaces |
| T721 |
3326-3328 |
IN |
denotes |
of |
| T722 |
3329-3332 |
DT |
denotes |
the |
| T723 |
3333-3334 |
NN |
denotes |
S |
| T724 |
3335-3343 |
NNS |
denotes |
proteins |
| T725 |
3344-3348 |
WDT |
denotes |
that |
| T726 |
3349-3352 |
VBP |
denotes |
are |
| T727 |
3353-3356 |
RB |
denotes |
not |
| T728 |
3357-3365 |
VBN |
denotes |
occluded |
| T729 |
3366-3368 |
IN |
denotes |
by |
| T730 |
3369-3377 |
JJ |
denotes |
N-linked |
| T731 |
3378-3385 |
NNS |
denotes |
glycans |
| T732 |
3387-3389 |
IN |
denotes |
In |
| T733 |
3390-3398 |
NN |
denotes |
addition |
| T734 |
3398-3399 |
-COMMA- |
denotes |
, |
| T735 |
3400-3402 |
PRP |
denotes |
we |
| T736 |
3403-3410 |
VBP |
denotes |
compare |
| T737 |
3411-3414 |
DT |
denotes |
the |
| T738 |
3415-3425 |
NNS |
denotes |
structures |
| T739 |
3426-3428 |
IN |
denotes |
of |
| T740 |
3429-3432 |
DT |
denotes |
the |
| T741 |
3433-3443 |
JJ |
denotes |
respective |
| T742 |
3444-3450 |
NN |
denotes |
glycan |
| T743 |
3451-3456 |
NNS |
denotes |
coats |
| T744 |
3457-3459 |
IN |
denotes |
of |
| T745 |
3460-3464 |
NN |
denotes |
SARS |
| T746 |
3465-3468 |
CC |
denotes |
and |
| T747 |
3469-3474 |
NN |
denotes |
HIV-1 |
| T748 |
3475-3483 |
NN |
denotes |
envelope |
| T749 |
3484-3492 |
NNS |
denotes |
proteins |
| T750 |
3493-3498 |
VBG |
denotes |
using |
| T751 |
3499-3512 |
NN |
denotes |
cryo-electron |
| T752 |
3513-3523 |
NN |
denotes |
microscopy |
| T753 |
3524-3525 |
-LRB- |
denotes |
( |
| T754 |
3525-3532 |
NN |
denotes |
cryo-EM |
| T755 |
3532-3533 |
-RRB- |
denotes |
) |
| T756 |
3534-3537 |
CC |
denotes |
and |
| T757 |
3538-3551 |
JJ |
denotes |
computational |
| T758 |
3552-3561 |
NN |
denotes |
modelling |
| T759 |
3561-3562 |
-COMMA- |
denotes |
, |
| T760 |
3563-3568 |
WDT |
denotes |
which |
| T761 |
3569-3578 |
VBP |
denotes |
delineate |
| T762 |
3579-3580 |
DT |
denotes |
a |
| T763 |
3581-3587 |
JJ |
denotes |
sparse |
| T764 |
3588-3594 |
NN |
denotes |
glycan |
| T765 |
3595-3601 |
NN |
denotes |
shield |
| T766 |
3602-3611 |
VBD |
denotes |
exhibited |
| T767 |
3612-3614 |
IN |
denotes |
on |
| T768 |
3615-3619 |
NNP |
denotes |
SARS |
| T769 |
3620-3621 |
NN |
denotes |
S |
| T770 |
3622-3630 |
VBN |
denotes |
compared |
| T771 |
3631-3635 |
IN |
denotes |
with |
| T772 |
3636-3641 |
JJ |
denotes |
other |
| T773 |
3642-3647 |
JJ |
denotes |
viral |
| T774 |
3648-3661 |
NNS |
denotes |
glycoproteins |
| T775 |
3663-3665 |
PRP |
denotes |
We |
| T776 |
3666-3675 |
RB |
denotes |
therefore |
| T777 |
3676-3685 |
VBD |
denotes |
undertook |
| T778 |
3686-3687 |
DT |
denotes |
a |
| T779 |
3688-3699 |
JJ |
denotes |
comparative |
| T780 |
3700-3708 |
NN |
denotes |
analysis |
| T781 |
3709-3711 |
IN |
denotes |
of |
| T782 |
3712-3717 |
JJ |
denotes |
viral |
| T783 |
3718-3724 |
NN |
denotes |
glycan |
| T784 |
3725-3732 |
NNS |
denotes |
shields |
| T785 |
3733-3737 |
IN |
denotes |
from |
| T786 |
3738-3751 |
VBN |
denotes |
characterized |
| T787 |
3752-3757 |
NN |
denotes |
class |
| T788 |
3758-3759 |
CD |
denotes |
I |
| T789 |
3760-3766 |
NN |
denotes |
fusion |
| T790 |
3767-3775 |
NNS |
denotes |
proteins |
| T791 |
3776-3778 |
TO |
denotes |
to |
| T792 |
3779-3788 |
VB |
denotes |
highlight |
| T793 |
3789-3792 |
WRB |
denotes |
how |
| T794 |
3793-3806 |
NN |
denotes |
glycosylation |
| T795 |
3807-3814 |
NN |
denotes |
density |
| T796 |
3815-3825 |
VBZ |
denotes |
influences |
| T797 |
3826-3843 |
JJ |
denotes |
oligomannose-type |
| T798 |
3844-3850 |
NN |
denotes |
glycan |
| T799 |
3851-3860 |
NN |
denotes |
abundance |
| T800 |
3860-3861 |
-COMMA- |
denotes |
, |
| T801 |
3862-3865 |
CC |
denotes |
and |
| T802 |
3866-3869 |
DT |
denotes |
the |
| T803 |
3870-3882 |
NN |
denotes |
relationship |
| T804 |
3883-3890 |
IN |
denotes |
between |
| T805 |
3891-3900 |
JJ |
denotes |
effective |
| T806 |
3901-3907 |
NN |
denotes |
glycan |
| T807 |
3908-3915 |
NNS |
denotes |
shields |
| T808 |
3916-3919 |
CC |
denotes |
and |
| T809 |
3920-3925 |
JJ |
denotes |
viral |
| T810 |
3926-3933 |
NN |
denotes |
evasion |
| T811 |
3934-3941 |
NN |
denotes |
ability |
| T812 |
3943-3951 |
RB |
denotes |
Together |
| T813 |
3951-3952 |
-COMMA- |
denotes |
, |
| T814 |
3953-3958 |
DT |
denotes |
these |
| T815 |
3959-3963 |
NNS |
denotes |
data |
| T816 |
3964-3974 |
VBP |
denotes |
underscore |
| T817 |
3975-3978 |
DT |
denotes |
the |
| T818 |
3979-3989 |
NN |
denotes |
importance |
| T819 |
3990-3992 |
IN |
denotes |
of |
| T820 |
3993-4006 |
NN |
denotes |
glycosylation |
| T821 |
4007-4009 |
IN |
denotes |
in |
| T822 |
4010-4015 |
JJ |
denotes |
viral |
| T823 |
4016-4022 |
JJ |
denotes |
immune |
| T824 |
4023-4030 |
NN |
denotes |
evasion |
| T825 |
4033-4040 |
NNS |
denotes |
Results |
| T826 |
4041-4044 |
CC |
denotes |
and |
| T827 |
4045-4055 |
NN |
denotes |
discussion |
| T828 |
4057-4063 |
NN |
denotes |
Glycan |
| T829 |
4064-4074 |
NN |
denotes |
processing |
| T830 |
4075-4077 |
IN |
denotes |
of |
| T831 |
4078-4086 |
JJ |
denotes |
trimeric |
| T832 |
4087-4091 |
NNS |
denotes |
SARS |
| T833 |
4092-4095 |
CC |
denotes |
and |
| T834 |
4096-4100 |
NNS |
denotes |
MERS |
| T835 |
4101-4106 |
NN |
denotes |
spike |
| T836 |
4107-4115 |
NNS |
denotes |
proteins |
| T837 |
4116-4118 |
TO |
denotes |
To |
| T838 |
4119-4127 |
VB |
denotes |
generate |
| T839 |
4128-4129 |
DT |
denotes |
a |
| T840 |
4130-4137 |
JJ |
denotes |
soluble |
| T841 |
4138-4143 |
NN |
denotes |
mimic |
| T842 |
4144-4146 |
IN |
denotes |
of |
| T843 |
4147-4150 |
DT |
denotes |
the |
| T844 |
4151-4156 |
JJ |
denotes |
viral |
| T845 |
4157-4158 |
NN |
denotes |
S |
| T846 |
4159-4167 |
NNS |
denotes |
proteins |
| T847 |
4167-4168 |
-COMMA- |
denotes |
, |
| T848 |
4169-4171 |
PRP |
denotes |
we |
| T849 |
4172-4176 |
VBD |
denotes |
used |
| T850 |
4177-4180 |
DT |
denotes |
the |
| T851 |
4181-4194 |
JJ |
denotes |
2P-stabilised |
| T852 |
4195-4206 |
JJ |
denotes |
native-like |
| T853 |
4207-4211 |
NNS |
denotes |
SARS |
| T854 |
4212-4215 |
CC |
denotes |
and |
| T855 |
4216-4220 |
NNS |
denotes |
MERS |
| T856 |
4221-4222 |
NN |
denotes |
S |
| T857 |
4223-4230 |
NN |
denotes |
protein |
| T858 |
4231-4239 |
NNS |
denotes |
antigens |
| T859 |
4239-4240 |
-COMMA- |
denotes |
, |
| T860 |
4241-4244 |
DT |
denotes |
the |
| T861 |
4245-4251 |
NN |
denotes |
design |
| T862 |
4252-4255 |
CC |
denotes |
and |
| T863 |
4256-4266 |
NNS |
denotes |
structures |
| T864 |
4267-4269 |
IN |
denotes |
of |
| T865 |
4270-4275 |
WDT |
denotes |
which |
| T866 |
4276-4280 |
VBP |
denotes |
have |
| T867 |
4281-4285 |
VBN |
denotes |
been |
| T868 |
4286-4295 |
VBN |
denotes |
described |
| T869 |
4296-4306 |
RB |
denotes |
previously |
| T870 |
4307-4309 |
IN |
denotes |
by |
| T871 |
4310-4318 |
NNP |
denotes |
Pallesen |
| T872 |
4319-4321 |
NNP |
denotes |
et |
| T873 |
4322-4327 |
NN |
denotes |
al.41 |
| T874 |
4329-4333 |
NNS |
denotes |
SARS |
| T875 |
4333-4334 |
-COMMA- |
denotes |
, |
| T876 |
4335-4339 |
NNS |
denotes |
MERS |
| T877 |
4340-4343 |
CC |
denotes |
and |
| T878 |
4344-4348 |
NN |
denotes |
HKU1 |
| T879 |
4349-4350 |
NN |
denotes |
S |
| T880 |
4351-4356 |
NNS |
denotes |
genes |
| T881 |
4357-4363 |
VBP |
denotes |
encode |
| T882 |
4364-4368 |
JJ |
denotes |
many |
| T883 |
4369-4377 |
JJ |
denotes |
N-linked |
| T884 |
4378-4384 |
NN |
denotes |
glycan |
| T885 |
4385-4392 |
NNS |
denotes |
sequons |
| T886 |
4392-4393 |
-SEMICOLON- |
denotes |
; |
| T887 |
4394-4396 |
CD |
denotes |
23 |
| T888 |
4396-4397 |
-COMMA- |
denotes |
, |
| T889 |
4398-4400 |
CD |
denotes |
23 |
| T890 |
4401-4404 |
CC |
denotes |
and |
| T891 |
4405-4407 |
CD |
denotes |
29 |
| T892 |
4407-4408 |
-COMMA- |
denotes |
, |
| T893 |
4409-4421 |
RB |
denotes |
respectively |
| T894 |
4422-4423 |
-LRB- |
denotes |
( |
| T895 |
4423-4430 |
NN |
denotes |
Fig. 1a |
| T896 |
4430-4431 |
-RRB- |
denotes |
) |
| T897 |
4433-4435 |
PRP |
denotes |
We |
| T898 |
4436-4445 |
RB |
denotes |
initially |
| T899 |
4446-4452 |
VBD |
denotes |
sought |
| T900 |
4453-4455 |
TO |
denotes |
to |
| T901 |
4456-4470 |
RB |
denotes |
quantitatively |
| T902 |
4471-4477 |
VB |
denotes |
assess |
| T903 |
4478-4481 |
DT |
denotes |
the |
| T904 |
4482-4493 |
NN |
denotes |
composition |
| T905 |
4494-4496 |
IN |
denotes |
of |
| T906 |
4497-4500 |
DT |
denotes |
the |
| T907 |
4501-4513 |
NN |
denotes |
carbohydrate |
| T908 |
4514-4524 |
NNS |
denotes |
structures |
| T909 |
4525-4534 |
VBD |
denotes |
displayed |
| T910 |
4535-4537 |
IN |
denotes |
on |
| T911 |
4538-4541 |
DT |
denotes |
the |
| T912 |
4542-4543 |
NN |
denotes |
S |
| T913 |
4544-4557 |
NNS |
denotes |
glycoproteins |
| T914 |
4559-4567 |
VBN |
denotes |
N-linked |
| T915 |
4568-4575 |
NNS |
denotes |
glycans |
| T916 |
4576-4580 |
VBD |
denotes |
were |
| T917 |
4581-4594 |
RB |
denotes |
enzymatically |
| T918 |
4595-4603 |
VBN |
denotes |
released |
| T919 |
4603-4604 |
-COMMA- |
denotes |
, |
| T920 |
4605-4618 |
RB |
denotes |
fluorescently |
| T921 |
4619-4627 |
VBN |
denotes |
labelled |
| T922 |
4627-4628 |
-COMMA- |
denotes |
, |
| T923 |
4629-4632 |
CC |
denotes |
and |
| T924 |
4633-4642 |
VBN |
denotes |
subjected |
| T925 |
4643-4645 |
TO |
denotes |
to |
| T926 |
4646-4657 |
JJ |
denotes |
hydrophilic |
| T927 |
4658-4669 |
NN |
denotes |
interaction |
| T928 |
4670-4702 |
NN |
denotes |
chromatography-ultra-performance |
| T929 |
4703-4709 |
NN |
denotes |
liquid |
| T930 |
4710-4724 |
NN |
denotes |
chromatography |
| T931 |
4725-4726 |
-LRB- |
denotes |
( |
| T932 |
4726-4736 |
NN |
denotes |
HILIC-UPLC |
| T933 |
4736-4737 |
-RRB- |
denotes |
) |
| T934 |
4739-4748 |
NN |
denotes |
Treatment |
| T935 |
4749-4753 |
IN |
denotes |
with |
| T936 |
4754-4769 |
NN |
denotes |
endoglycosidase |
| T937 |
4770-4771 |
NN |
denotes |
H |
| T938 |
4772-4773 |
-LRB- |
denotes |
( |
| T939 |
4773-4777 |
NNP |
denotes |
Endo |
| T940 |
4778-4779 |
NN |
denotes |
H |
| T941 |
4779-4780 |
-RRB- |
denotes |
) |
| T942 |
4781-4789 |
VBD |
denotes |
revealed |
| T943 |
4790-4791 |
DT |
denotes |
a |
| T944 |
4792-4802 |
NN |
denotes |
population |
| T945 |
4803-4804 |
-LRB- |
denotes |
( |
| T946 |
4804-4808 |
NN |
denotes |
SARS |
| T947 |
4809-4813 |
CD |
denotes |
32.2 |
| T948 |
4813-4814 |
NN |
denotes |
% |
| T949 |
4814-4815 |
-SEMICOLON- |
denotes |
; |
| T950 |
4816-4820 |
NNS |
denotes |
MERS |
| T951 |
4821-4825 |
CD |
denotes |
33.8 |
| T952 |
4825-4826 |
NN |
denotes |
% |
| T953 |
4826-4827 |
-COMMA- |
denotes |
, |
| T954 |
4828-4832 |
NN |
denotes |
HKU1 |
| T955 |
4833-4837 |
CD |
denotes |
25.0 |
| T956 |
4837-4838 |
NN |
denotes |
% |
| T957 |
4838-4839 |
-RRB- |
denotes |
) |
| T958 |
4840-4842 |
IN |
denotes |
of |
| T959 |
4843-4857 |
VBN |
denotes |
underprocessed |
| T960 |
4858-4875 |
JJ |
denotes |
oligomannose-type |
| T961 |
4876-4883 |
NNS |
denotes |
glycans |
| T962 |
4884-4885 |
-LRB- |
denotes |
( |
| T963 |
4885-4892 |
NN |
denotes |
Fig. 1b |
| T964 |
4892-4893 |
-RRB- |
denotes |
) |
| T965 |
4895-4899 |
DT |
denotes |
This |
| T966 |
4900-4911 |
NN |
denotes |
observation |
| T967 |
4912-4914 |
IN |
denotes |
of |
| T968 |
4915-4919 |
CC |
denotes |
both |
| T969 |
4920-4927 |
JJ |
denotes |
complex |
| T970 |
4928-4931 |
CC |
denotes |
and |
| T971 |
4932-4949 |
JJ |
denotes |
oligomannose-type |
| T972 |
4950-4957 |
NNS |
denotes |
glycans |
| T973 |
4958-4965 |
VBZ |
denotes |
reveals |
| T974 |
4966-4970 |
IN |
denotes |
that |
| T975 |
4971-4974 |
DT |
denotes |
the |
| T976 |
4975-4983 |
NN |
denotes |
majority |
| T977 |
4984-4986 |
IN |
denotes |
of |
| T978 |
4987-4995 |
JJ |
denotes |
N-linked |
| T979 |
4996-5003 |
NNS |
denotes |
glycans |
| T980 |
5004-5007 |
MD |
denotes |
can |
| T981 |
5008-5010 |
VB |
denotes |
be |
| T982 |
5011-5020 |
VBN |
denotes |
processed |
| T983 |
5020-5021 |
-COMMA- |
denotes |
, |
| T984 |
5022-5030 |
IN |
denotes |
although |
| T985 |
5031-5036 |
EX |
denotes |
there |
| T986 |
5037-5039 |
VBZ |
denotes |
is |
| T987 |
5040-5047 |
JJ |
denotes |
limited |
| T988 |
5048-5058 |
NN |
denotes |
processing |
| T989 |
5059-5061 |
IN |
denotes |
at |
| T990 |
5062-5070 |
JJ |
denotes |
specific |
| T991 |
5071-5076 |
NNS |
denotes |
sites |
| T992 |
5077-5083 |
IN |
denotes |
across |
| T993 |
5084-5087 |
DT |
denotes |
the |
| T994 |
5088-5089 |
NN |
denotes |
S |
| T995 |
5090-5098 |
NNS |
denotes |
proteins |
| T996 |
5100-5102 |
PRP |
denotes |
It |
| T997 |
5103-5105 |
VBZ |
denotes |
is |
| T998 |
5106-5110 |
RB |
denotes |
also |
| T999 |
5111-5122 |
JJ |
denotes |
interesting |
| T1000 |
5123-5125 |
TO |
denotes |
to |
| T1001 |
5126-5130 |
VB |
denotes |
note |
| T1002 |
5131-5135 |
IN |
denotes |
that |
| T1003 |
5136-5139 |
DT |
denotes |
the |
| T1004 |
5140-5152 |
NN |
denotes |
distribution |
| T1005 |
5153-5155 |
IN |
denotes |
of |
| T1006 |
5156-5173 |
JJ |
denotes |
oligomannose-type |
| T1007 |
5174-5181 |
NNS |
denotes |
glycans |
| T1008 |
5182-5185 |
VBD |
denotes |
was |
| T1009 |
5186-5191 |
JJ |
denotes |
broad |
| T1010 |
5191-5192 |
-COMMA- |
denotes |
, |
| T1011 |
5193-5197 |
IN |
denotes |
with |
| T1012 |
5198-5209 |
NN |
denotes |
Man5GlcNAc2 |
| T1013 |
5210-5212 |
TO |
denotes |
to |
| T1014 |
5213-5224 |
NN |
denotes |
Man9GlcNAc2 |
| T1015 |
5225-5232 |
NNS |
denotes |
glycans |
| T1016 |
5233-5236 |
DT |
denotes |
all |
| T1017 |
5237-5244 |
VBP |
denotes |
present |
| T1018 |
5244-5245 |
-COMMA- |
denotes |
, |
| T1019 |
5246-5253 |
IN |
denotes |
without |
| T1020 |
5254-5257 |
CD |
denotes |
one |
| T1021 |
5258-5268 |
JJ |
denotes |
particular |
| T1022 |
5269-5277 |
JJ |
denotes |
dominant |
| T1023 |
5278-5282 |
NN |
denotes |
peak |
| T1024 |
5282-5283 |
-COMMA- |
denotes |
, |
| T1025 |
5284-5286 |
IN |
denotes |
as |
| T1026 |
5287-5289 |
VBZ |
denotes |
is |
| T1027 |
5290-5293 |
DT |
denotes |
the |
| T1028 |
5294-5298 |
NN |
denotes |
case |
| T1029 |
5299-5302 |
IN |
denotes |
for |
| T1030 |
5303-5307 |
DT |
denotes |
some |
| T1031 |
5308-5313 |
JJ |
denotes |
viral |
| T1032 |
5314-5327 |
NNS |
denotes |
glycoproteins |
| T1033 |
5327-5328 |
-COMMA- |
denotes |
, |
| T1034 |
5329-5333 |
JJ |
denotes |
such |
| T1035 |
5334-5336 |
IN |
denotes |
as |
| T1036 |
5337-5342 |
NN |
denotes |
HIV-1 |
| T1037 |
5343-5348 |
NN |
denotes |
Env36 |
| T1038 |
5350-5353 |
DT |
denotes |
The |
| T1039 |
5354-5364 |
NN |
denotes |
proportion |
| T1040 |
5365-5367 |
IN |
denotes |
of |
| T1041 |
5368-5385 |
JJ |
denotes |
oligomannose-type |
| T1042 |
5386-5393 |
NNS |
denotes |
glycans |
| T1043 |
5394-5396 |
IN |
denotes |
on |
| T1044 |
5397-5408 |
JJ |
denotes |
recombinant |
| T1045 |
5409-5420 |
NN |
denotes |
coronavirus |
| T1046 |
5421-5422 |
NN |
denotes |
S |
| T1047 |
5423-5431 |
NNS |
denotes |
proteins |
| T1048 |
5432-5434 |
VBZ |
denotes |
is |
| T1049 |
5435-5445 |
JJ |
denotes |
consistent |
| T1050 |
5446-5450 |
IN |
denotes |
with |
| T1051 |
5451-5459 |
JJ |
denotes |
previous |
| T1052 |
5460-5467 |
NNS |
denotes |
studies |
| T1053 |
5468-5477 |
VBN |
denotes |
performed |
| T1054 |
5478-5480 |
IN |
denotes |
on |
| T1055 |
5481-5488 |
RB |
denotes |
virally |
| T1056 |
5489-5496 |
VBN |
denotes |
derived |
| T1057 |
5497-5501 |
NNS |
denotes |
MERS |
| T1058 |
5502-5505 |
CC |
denotes |
and |
| T1059 |
5506-5510 |
NN |
denotes |
SARS |
| T1060 |
5511-5522 |
NN |
denotes |
coronavirus |
| T1061 |
5523-5524 |
NN |
denotes |
S |
| T1062 |
5525-5538 |
NN |
denotes |
proteins17,42 |
| T1063 |
5540-5553 |
NNS |
denotes |
Coronaviruses |
| T1064 |
5554-5558 |
VBP |
denotes |
have |
| T1065 |
5559-5563 |
VBN |
denotes |
been |
| T1066 |
5564-5574 |
RB |
denotes |
previously |
| T1067 |
5575-5579 |
VBN |
denotes |
been |
| T1068 |
5580-5588 |
VBN |
denotes |
reported |
| T1069 |
5589-5591 |
TO |
denotes |
to |
| T1070 |
5592-5596 |
VB |
denotes |
form |
| T1071 |
5597-5604 |
NNS |
denotes |
virions |
| T1072 |
5605-5607 |
IN |
denotes |
by |
| T1073 |
5608-5615 |
VBG |
denotes |
budding |
| T1074 |
5616-5620 |
IN |
denotes |
into |
| T1075 |
5621-5624 |
DT |
denotes |
the |
| T1076 |
5625-5630 |
NN |
denotes |
lumen |
| T1077 |
5631-5633 |
IN |
denotes |
of |
| T1078 |
5634-5645 |
JJ |
denotes |
endoplasmic |
| T1079 |
5646-5661 |
JJ |
denotes |
reticulum-Golgi |
| T1080 |
5662-5674 |
JJ |
denotes |
intermediate |
| T1081 |
5675-5687 |
NNS |
denotes |
compartments |
| T1082 |
5688-5689 |
-LRB- |
denotes |
( |
| T1083 |
5689-5694 |
NN |
denotes |
ERGIC |
| T1084 |
5694-5695 |
-RRB- |
denotes |
) |
| T1085 |
5695-5700 |
CD |
denotes |
43,44 |
| T1086 |
5702-5714 |
NNS |
denotes |
Observations |
| T1087 |
5715-5717 |
IN |
denotes |
of |
| T1088 |
5718-5725 |
NN |
denotes |
hybrid- |
| T1089 |
5726-5729 |
CC |
denotes |
and |
| T1090 |
5730-5742 |
JJ |
denotes |
complex-type |
| T1091 |
5743-5750 |
NNS |
denotes |
glycans |
| T1092 |
5751-5753 |
IN |
denotes |
on |
| T1093 |
5754-5761 |
RB |
denotes |
virally |
| T1094 |
5762-5769 |
VBN |
denotes |
derived |
| T1095 |
5770-5783 |
NN |
denotes |
material17,42 |
| T1096 |
5784-5789 |
MD |
denotes |
would |
| T1097 |
5789-5790 |
-COMMA- |
denotes |
, |
| T1098 |
5791-5798 |
RB |
denotes |
however |
| T1099 |
5798-5799 |
-COMMA- |
denotes |
, |
| T1100 |
5800-5807 |
VBP |
denotes |
suggest |
| T1101 |
5808-5812 |
IN |
denotes |
that |
| T1102 |
5813-5815 |
PRP |
denotes |
it |
| T1103 |
5816-5818 |
VBZ |
denotes |
is |
| T1104 |
5819-5825 |
JJ |
denotes |
likely |
| T1105 |
5826-5830 |
IN |
denotes |
that |
| T1106 |
5831-5842 |
NN |
denotes |
coronavirus |
| T1107 |
5843-5850 |
NNS |
denotes |
virions |
| T1108 |
5851-5857 |
VBP |
denotes |
travel |
| T1109 |
5858-5865 |
IN |
denotes |
through |
| T1110 |
5866-5869 |
DT |
denotes |
the |
| T1111 |
5870-5875 |
NNP |
denotes |
Golgi |
| T1112 |
5876-5885 |
NN |
denotes |
apparatus |
| T1113 |
5886-5891 |
IN |
denotes |
after |
| T1114 |
5892-5898 |
NN |
denotes |
virion |
| T1115 |
5899-5908 |
NN |
denotes |
formation |
| T1116 |
5909-5911 |
IN |
denotes |
in |
| T1117 |
5912-5915 |
DT |
denotes |
the |
| T1118 |
5916-5921 |
NN |
denotes |
ERGIC |
| T1119 |
5922-5924 |
IN |
denotes |
en |
| T1120 |
5925-5930 |
NN |
denotes |
route |
| T1121 |
5931-5933 |
TO |
denotes |
to |
| T1122 |
5934-5937 |
DT |
denotes |
the |
| T1123 |
5938-5942 |
NN |
denotes |
cell |
| T1124 |
5943-5950 |
NN |
denotes |
surface |
| T1125 |
5950-5951 |
-COMMA- |
denotes |
, |
| T1126 |
5952-5956 |
RB |
denotes |
thus |
| T1127 |
5957-5967 |
VBG |
denotes |
supporting |
| T1128 |
5968-5979 |
JJ |
denotes |
recombinant |
| T1129 |
5980-5990 |
NNS |
denotes |
immunogens |
| T1130 |
5991-5993 |
IN |
denotes |
as |
| T1131 |
5994-6000 |
NNS |
denotes |
models |
| T1132 |
6001-6003 |
IN |
denotes |
of |
| T1133 |
6004-6009 |
JJ |
denotes |
viral |
| T1134 |
6010-6023 |
NNS |
denotes |
glycoproteins |
| T1135 |
6025-6029 |
NNP |
denotes |
Fig. |
| T1136 |
6030-6031 |
CD |
denotes |
1 |
| T1137 |
6032-6045 |
JJ |
denotes |
Compositional |
| T1138 |
6046-6054 |
NN |
denotes |
analysis |
| T1139 |
6055-6057 |
IN |
denotes |
of |
| T1140 |
6058-6062 |
NNP |
denotes |
SARS |
| T1141 |
6062-6063 |
-COMMA- |
denotes |
, |
| T1142 |
6064-6068 |
NNS |
denotes |
MERS |
| T1143 |
6069-6072 |
CC |
denotes |
and |
| T1144 |
6073-6077 |
NN |
denotes |
HKU1 |
| T1145 |
6078-6085 |
NNS |
denotes |
glycans |
| T1146 |
6087-6088 |
DT |
denotes |
a |
| T1147 |
6089-6098 |
JJ |
denotes |
Schematic |
| T1148 |
6099-6113 |
NN |
denotes |
representation |
| T1149 |
6114-6116 |
IN |
denotes |
of |
| T1150 |
6117-6121 |
NNP |
denotes |
SARS |
| T1151 |
6121-6122 |
-COMMA- |
denotes |
, |
| T1152 |
6123-6127 |
NNS |
denotes |
MERS |
| T1153 |
6128-6131 |
CC |
denotes |
and |
| T1154 |
6132-6136 |
NN |
denotes |
HKU1 |
| T1155 |
6137-6148 |
NN |
denotes |
coronavirus |
| T1156 |
6149-6150 |
NN |
denotes |
S |
| T1157 |
6151-6164 |
NNS |
denotes |
glycoproteins |
| T1158 |
6164-6165 |
-COMMA- |
denotes |
, |
| T1159 |
6166-6173 |
VBG |
denotes |
showing |
| T1160 |
6174-6177 |
DT |
denotes |
the |
| T1161 |
6178-6187 |
NNS |
denotes |
positions |
| T1162 |
6188-6190 |
IN |
denotes |
of |
| T1163 |
6191-6199 |
JJ |
denotes |
N-linked |
| T1164 |
6200-6213 |
NN |
denotes |
glycosylation |
| T1165 |
6214-6224 |
JJ |
denotes |
amino-acid |
| T1166 |
6225-6232 |
NNS |
denotes |
sequons |
| T1167 |
6233-6234 |
-LRB- |
denotes |
( |
| T1168 |
6234-6239 |
NN |
denotes |
NXS/T |
| T1169 |
6239-6240 |
-COMMA- |
denotes |
, |
| T1170 |
6241-6246 |
WRB |
denotes |
where |
| T1171 |
6247-6252 |
NN |
denotes |
X ≠ P |
| T1172 |
6252-6253 |
-RRB- |
denotes |
) |
| T1173 |
6254-6259 |
VBN |
denotes |
shown |
| T1174 |
6260-6262 |
IN |
denotes |
as |
| T1175 |
6263-6271 |
NNS |
denotes |
branches |
| T1177 |
6813-6830 |
JJ |
denotes |
Oligomannose-type |
| T1178 |
6831-6838 |
NNS |
denotes |
glycans |
| T1179 |
6839-6842 |
VBP |
denotes |
are |
| T1180 |
6843-6856 |
RB |
denotes |
schematically |
| T1181 |
6857-6866 |
VBN |
denotes |
annotated |
| T1182 |
6867-6871 |
IN |
denotes |
with |
| T1183 |
6872-6879 |
NN |
denotes |
mannose |
| T1184 |
6880-6888 |
NNS |
denotes |
residues |
| T1185 |
6889-6891 |
IN |
denotes |
as |
| T1186 |
6892-6897 |
JJ |
denotes |
green |
| T1187 |
6898-6905 |
NNS |
denotes |
circles |
| T1188 |
6906-6909 |
CC |
denotes |
and |
| T1189 |
6910-6916 |
NN |
denotes |
GlcNAc |
| T1190 |
6917-6925 |
NNS |
denotes |
residues |
| T1191 |
6926-6928 |
IN |
denotes |
as |
| T1192 |
6929-6933 |
JJ |
denotes |
blue |
| T1193 |
6934-6941 |
NNS |
denotes |
squares |
| T1194 |
6943-6945 |
TO |
denotes |
To |
| T1195 |
6946-6955 |
VB |
denotes |
ascertain |
| T1196 |
6956-6959 |
DT |
denotes |
the |
| T1197 |
6960-6967 |
JJ |
denotes |
precise |
| T1198 |
6968-6978 |
NNS |
denotes |
structures |
| T1199 |
6979-6981 |
IN |
denotes |
of |
| T1200 |
6982-6990 |
JJ |
denotes |
N-linked |
| T1201 |
6991-6998 |
NNS |
denotes |
glycans |
| T1202 |
6998-6999 |
-COMMA- |
denotes |
, |
| T1203 |
7000-7006 |
NN |
denotes |
glycan |
| T1204 |
7007-7012 |
NNS |
denotes |
pools |
| T1205 |
7013-7015 |
IN |
denotes |
of |
| T1206 |
7016-7020 |
DT |
denotes |
each |
| T1207 |
7021-7032 |
NN |
denotes |
coronavirus |
| T1208 |
7033-7034 |
NN |
denotes |
S |
| T1209 |
7035-7042 |
NN |
denotes |
protein |
| T1210 |
7043-7047 |
VBD |
denotes |
were |
| T1211 |
7048-7056 |
VBN |
denotes |
analysed |
| T1212 |
7057-7059 |
IN |
denotes |
by |
| T1213 |
7060-7072 |
JJ |
denotes |
negative-ion |
| T1214 |
7073-7098 |
NN |
denotes |
ion-mobility-electrospray |
| T1215 |
7099-7109 |
NN |
denotes |
ionisation |
| T1216 |
7110-7114 |
NN |
denotes |
mass |
| T1217 |
7115-7127 |
NN |
denotes |
spectrometry |
| T1218 |
7128-7129 |
-LRB- |
denotes |
( |
| T1219 |
7129-7135 |
NN |
denotes |
IM-ESI |
| T1220 |
7136-7138 |
NN |
denotes |
MS |
| T1221 |
7138-7139 |
-RRB- |
denotes |
) |
| T1222 |
7140-7141 |
-LRB- |
denotes |
( |
| T1223 |
7141-7154 |
JJ |
denotes |
Supplementary |
| T1224 |
7155-7161 |
NN |
denotes |
Fig. 1 |
| T1225 |
7161-7162 |
-RRB- |
denotes |
) |
| T1226 |
7164-7174 |
JJ |
denotes |
Consistent |
| T1227 |
7175-7179 |
IN |
denotes |
with |
| T1228 |
7180-7183 |
DT |
denotes |
the |
| T1229 |
7184-7188 |
NN |
denotes |
UPLC |
| T1230 |
7189-7193 |
NNS |
denotes |
data |
| T1231 |
7193-7194 |
-COMMA- |
denotes |
, |
| T1232 |
7195-7201 |
NNP |
denotes |
IM-ESI |
| T1233 |
7202-7204 |
NNP |
denotes |
MS |
| T1234 |
7205-7214 |
VBD |
denotes |
confirmed |
| T1235 |
7215-7217 |
DT |
denotes |
an |
| T1236 |
7218-7223 |
NN |
denotes |
array |
| T1237 |
7224-7226 |
IN |
denotes |
of |
| T1238 |
7227-7239 |
JJ |
denotes |
complex-type |
| T1239 |
7240-7247 |
NNS |
denotes |
glycans |
| T1240 |
7248-7255 |
VBG |
denotes |
ranging |
| T1241 |
7256-7260 |
IN |
denotes |
from |
| T1242 |
7261-7266 |
NN |
denotes |
mono- |
| T1243 |
7267-7269 |
TO |
denotes |
to |
| T1244 |
7270-7285 |
JJ |
denotes |
tetra-antennary |
| T1245 |
7285-7286 |
-COMMA- |
denotes |
, |
| T1246 |
7287-7290 |
CC |
denotes |
but |
| T1247 |
7291-7295 |
RB |
denotes |
also |
| T1248 |
7296-7309 |
NN |
denotes |
oligomannose- |
| T1249 |
7310-7313 |
CC |
denotes |
and |
| T1250 |
7314-7325 |
JJ |
denotes |
hybrid-type |
| T1251 |
7326-7333 |
NNS |
denotes |
glycans |
| T1252 |
7335-7338 |
DT |
denotes |
The |
| T1253 |
7339-7345 |
NN |
denotes |
glycan |
| T1254 |
7346-7358 |
NNS |
denotes |
compositions |
| T1255 |
7359-7372 |
VBN |
denotes |
characterised |
| T1256 |
7373-7375 |
IN |
denotes |
in |
| T1257 |
7376-7379 |
DT |
denotes |
the |
| T1258 |
7380-7387 |
NNS |
denotes |
spectra |
| T1259 |
7388-7392 |
VBD |
denotes |
were |
| T1260 |
7393-7400 |
RB |
denotes |
largely |
| T1261 |
7401-7410 |
JJ |
denotes |
invariant |
| T1262 |
7411-7416 |
IN |
denotes |
among |
| T1263 |
7417-7420 |
DT |
denotes |
the |
| T1264 |
7421-7434 |
NNS |
denotes |
coronaviruses |
| T1265 |
7435-7439 |
IN |
denotes |
with |
| T1266 |
7440-7442 |
DT |
denotes |
no |
| T1267 |
7443-7448 |
JJ |
denotes |
major |
| T1268 |
7449-7459 |
JJ |
denotes |
structural |
| T1269 |
7460-7471 |
NNS |
denotes |
differences |
| T1270 |
7472-7480 |
VBN |
denotes |
observed |
| T1271 |
7483-7493 |
NN |
denotes |
Clustering |
| T1272 |
7494-7496 |
IN |
denotes |
of |
| T1273 |
7497-7511 |
JJ |
denotes |
underprocessed |
| T1274 |
7512-7519 |
NNS |
denotes |
glycans |
| T1275 |
7520-7522 |
IN |
denotes |
on |
| T1276 |
7523-7527 |
NNS |
denotes |
MERS |
| T1277 |
7528-7529 |
NN |
denotes |
S |
| T68424 |
7530-7532 |
PRP |
denotes |
We |
| T7134 |
7533-7545 |
RB |
denotes |
subsequently |
| T76564 |
7546-7555 |
VBD |
denotes |
performed |
| T84609 |
7556-7568 |
NN |
denotes |
glycopeptide |
| T22031 |
7569-7577 |
NN |
denotes |
analysis |
| T45093 |
7578-7580 |
TO |
denotes |
to |
| T79801 |
7581-7590 |
VB |
denotes |
ascertain |
| T52563 |
7591-7594 |
DT |
denotes |
the |
| T41193 |
7595-7607 |
NNS |
denotes |
compositions |
| T88928 |
7608-7610 |
IN |
denotes |
of |
| T13523 |
7611-7618 |
NNS |
denotes |
glycans |
| T54555 |
7619-7621 |
IN |
denotes |
at |
| T13277 |
7622-7625 |
DT |
denotes |
all |
| T38634 |
7626-7628 |
IN |
denotes |
of |
| T33467 |
7629-7632 |
DT |
denotes |
the |
| T42060 |
7633-7642 |
JJ |
denotes |
potential |
| T99523 |
7643-7651 |
JJ |
denotes |
N-linked |
| T99446 |
7652-7665 |
NN |
denotes |
glycosylation |
| T21366 |
7666-7671 |
NNS |
denotes |
sites |
| T22927 |
7672-7673 |
-LRB- |
denotes |
( |
| T74512 |
7673-7677 |
NNS |
denotes |
PNGs |
| T79360 |
7677-7678 |
-RRB- |
denotes |
) |
| T78780 |
7680-7684 |
NNS |
denotes |
MERS |
| T54967 |
7684-7685 |
-COMMA- |
denotes |
, |
| T43119 |
7686-7690 |
NN |
denotes |
SARS |
| T79243 |
7691-7694 |
CC |
denotes |
and |
| T12013 |
7695-7699 |
NN |
denotes |
HKU1 |
| T9774 |
7700-7711 |
JJ |
denotes |
recombinant |
| T20303 |
7712-7713 |
NN |
denotes |
S |
| T31427 |
7714-7722 |
NNS |
denotes |
proteins |
| T76296 |
7723-7727 |
VBD |
denotes |
were |
| T47095 |
7728-7735 |
VBN |
denotes |
reduced |
| T76573 |
7735-7736 |
-COMMA- |
denotes |
, |
| T86504 |
7737-7746 |
VBN |
denotes |
alkylated |
| T10460 |
7747-7750 |
CC |
denotes |
and |
| T8652 |
7751-7759 |
VBN |
denotes |
digested |
| T27352 |
7760-7764 |
IN |
denotes |
with |
| T80310 |
7765-7767 |
DT |
denotes |
an |
| T76651 |
7768-7778 |
NN |
denotes |
assortment |
| T63553 |
7779-7781 |
IN |
denotes |
of |
| T52033 |
7782-7791 |
NNS |
denotes |
proteases |
| T24947 |
7792-7794 |
TO |
denotes |
to |
| T50688 |
7795-7800 |
VB |
denotes |
yield |
| T80082 |
7801-7814 |
NNS |
denotes |
glycopeptides |
| T99831 |
7814-7815 |
-COMMA- |
denotes |
, |
| T33781 |
7816-7821 |
WDT |
denotes |
which |
| T20638 |
7822-7826 |
VBD |
denotes |
were |
| T35120 |
7827-7836 |
VBN |
denotes |
subjected |
| T25962 |
7837-7839 |
TO |
denotes |
to |
| T78058 |
7840-7847 |
JJ |
denotes |
in-line |
| T75900 |
7848-7854 |
JJ |
denotes |
liquid |
| T31589 |
7855-7874 |
NN |
denotes |
chromatography-mass |
| T18666 |
7875-7887 |
NN |
denotes |
spectrometry |
| T45711 |
7888-7889 |
-LRB- |
denotes |
( |
| T15066 |
7889-7894 |
NN |
denotes |
LC-MS |
| T82375 |
7894-7895 |
-RRB- |
denotes |
) |
| T18459 |
7897-7901 |
DT |
denotes |
This |
| T55071 |
7902-7910 |
VBD |
denotes |
revealed |
| T51085 |
7911-7923 |
JJ |
denotes |
differential |
| T88367 |
7924-7930 |
NNS |
denotes |
levels |
| T70083 |
7931-7933 |
IN |
denotes |
of |
| T79246 |
7934-7946 |
NN |
denotes |
oligomannose |
| T85438 |
7946-7947 |
-COMMA- |
denotes |
, |
| T39117 |
7948-7954 |
NN |
denotes |
hybrid |
| T22989 |
7954-7955 |
-COMMA- |
denotes |
, |
| T20968 |
7956-7959 |
CC |
denotes |
and |
| T49737 |
7960-7972 |
JJ |
denotes |
complex-type |
| T78484 |
7973-7979 |
NN |
denotes |
glycan |
| T72051 |
7980-7991 |
NNS |
denotes |
populations |
| T75452 |
7992-7993 |
-LRB- |
denotes |
( |
| T62826 |
7993-8000 |
NN |
denotes |
Fig. 2a |
| T41174 |
8000-8001 |
-COMMA- |
denotes |
, |
| T16399 |
8002-8003 |
NN |
denotes |
b |
| T14860 |
8003-8004 |
-RRB- |
denotes |
) |
| T56558 |
8006-8011 |
VBG |
denotes |
Using |
| T28749 |
8012-8022 |
NNS |
denotes |
structures |
| T33039 |
8023-8025 |
IN |
denotes |
of |
| T74888 |
8026-8029 |
DT |
denotes |
the |
| T85424 |
8030-8038 |
JJ |
denotes |
trimeric |
| T52754 |
8039-8043 |
NNS |
denotes |
MERS |
| T31179 |
8044-8047 |
CC |
denotes |
and |
| T61603 |
8048-8052 |
NNP |
denotes |
SARS |
| T11525 |
8053-8054 |
NN |
denotes |
S |
| T81925 |
8055-8063 |
NNS |
denotes |
proteins |
| T15094 |
8064-8065 |
-LRB- |
denotes |
( |
| T17734 |
8065-8068 |
NN |
denotes |
PDB |
| T49127 |
8069-8071 |
NN |
denotes |
ID |
| T41188 |
8071-8072 |
-COLON- |
denotes |
: |
| T82842 |
8073-8077 |
NN |
denotes |
5X59 |
| T94035 |
8078-8081 |
CC |
denotes |
and |
| T4129 |
8082-8086 |
NN |
denotes |
5X58 |
| T93804 |
8086-8087 |
-COMMA- |
denotes |
, |
| T25861 |
8088-8100 |
RB |
denotes |
respectively |
| T44190 |
8100-8101 |
-RRB- |
denotes |
) |
| T83072 |
8101-8102 |
-COMMA- |
denotes |
, |
| T56951 |
8103-8105 |
PRP |
denotes |
we |
| T84875 |
8106-8115 |
VBD |
denotes |
generated |
| T16354 |
8116-8122 |
NNS |
denotes |
models |
| T90159 |
8123-8125 |
IN |
denotes |
of |
| T64487 |
8126-8131 |
RB |
denotes |
fully |
| T51670 |
8132-8144 |
VBN |
denotes |
glycosylated |
| T11954 |
8145-8156 |
NN |
denotes |
coronavirus |
| T96423 |
8157-8163 |
NNS |
denotes |
spikes |
| T16192 |
8164-8169 |
VBG |
denotes |
using |
| T41991 |
8170-8184 |
RB |
denotes |
experimentally |
| T34640 |
8185-8195 |
VBN |
denotes |
determined |
| T73736 |
8196-8202 |
NN |
denotes |
glycan |
| T93669 |
8203-8215 |
NNS |
denotes |
compositions |
| T17443 |
8216-8217 |
-LRB- |
denotes |
( |
| T79807 |
8217-8224 |
NN |
denotes |
Fig. 3a |
| T84889 |
8224-8225 |
-COMMA- |
denotes |
, |
| T56236 |
8226-8227 |
NN |
denotes |
b |
| T87991 |
8227-8228 |
-RRB- |
denotes |
) |
| T91445 |
8230-8234 |
DT |
denotes |
This |
| T32785 |
8235-8243 |
VBD |
denotes |
revealed |
| T90326 |
8244-8248 |
IN |
denotes |
that |
| T49774 |
8249-8266 |
JJ |
denotes |
oligomannose-type |
| T77922 |
8267-8274 |
NNS |
denotes |
glycans |
| T26521 |
8275-8277 |
IN |
denotes |
on |
| T6952 |
8278-8282 |
NNS |
denotes |
MERS |
| T82084 |
8283-8284 |
NN |
denotes |
S |
| T36749 |
8285-8296 |
VBP |
denotes |
co-localize |
| T66900 |
8297-8299 |
TO |
denotes |
to |
| T31749 |
8300-8308 |
JJ |
denotes |
specific |
| T40780 |
8309-8317 |
NNS |
denotes |
clusters |
| T42499 |
8318-8320 |
IN |
denotes |
on |
| T28913 |
8321-8324 |
DT |
denotes |
the |
| T99242 |
8325-8329 |
NN |
denotes |
head |
| T67844 |
8330-8332 |
IN |
denotes |
of |
| T51016 |
8333-8336 |
DT |
denotes |
the |
| T78718 |
8337-8338 |
NN |
denotes |
S |
| T82870 |
8339-8346 |
NN |
denotes |
protein |
| T5951 |
8346-8347 |
-COMMA- |
denotes |
, |
| T72350 |
8348-8358 |
VBG |
denotes |
consisting |
| T71605 |
8359-8361 |
IN |
denotes |
of |
| T54609 |
8362-8369 |
NNS |
denotes |
glycans |
| T31759 |
8370-8372 |
IN |
denotes |
at |
| T18955 |
8373-8379 |
NN |
denotes |
Asn155 |
| T13208 |
8379-8380 |
-COMMA- |
denotes |
, |
| T79227 |
8381-8387 |
NN |
denotes |
Asn166 |
| T49578 |
8387-8388 |
-COMMA- |
denotes |
, |
| T66915 |
8389-8392 |
CC |
denotes |
and |
| T34772 |
8393-8399 |
NN |
denotes |
Asn236 |
| T34488 |
8400-8401 |
-LRB- |
denotes |
( |
| T13786 |
8401-8408 |
NN |
denotes |
Fig. 3a |
| T99953 |
8408-8409 |
-RRB- |
denotes |
) |
| T88607 |
8411-8413 |
PRP |
denotes |
We |
| T60015 |
8414-8426 |
VBD |
denotes |
hypothesized |
| T95784 |
8427-8431 |
IN |
denotes |
that |
| T39313 |
8432-8435 |
DT |
denotes |
the |
| T91856 |
8436-8441 |
RB |
denotes |
fully |
| T9118 |
8442-8459 |
JJ |
denotes |
oligomannose-type |
| T9345 |
8460-8466 |
NN |
denotes |
glycan |
| T56514 |
8467-8477 |
NN |
denotes |
population |
| T52338 |
8478-8480 |
IN |
denotes |
in |
| T2332 |
8481-8485 |
DT |
denotes |
this |
| T67337 |
8486-8493 |
NN |
denotes |
cluster |
| T32151 |
8494-8500 |
VBZ |
denotes |
arises |
| T48770 |
8501-8504 |
JJ |
denotes |
due |
| T86749 |
8505-8507 |
TO |
denotes |
to |
| T19511 |
8508-8511 |
DT |
denotes |
the |
| T6499 |
8512-8520 |
VBN |
denotes |
hindered |
| T30499 |
8521-8534 |
NN |
denotes |
accessibility |
| T56293 |
8535-8537 |
IN |
denotes |
of |
| T22648 |
8538-8544 |
NN |
denotes |
glycan |
| T94530 |
8545-8555 |
NN |
denotes |
processing |
| T53545 |
8556-8563 |
NNS |
denotes |
enzymes |
| T29305 |
8564-8566 |
TO |
denotes |
to |
| T79028 |
8567-8573 |
VB |
denotes |
access |
| T66117 |
8574-8577 |
DT |
denotes |
the |
| T4310 |
8578-8587 |
NN |
denotes |
substrate |
| T8069 |
8588-8596 |
NN |
denotes |
glycan28 |
| T69590 |
8598-8600 |
IN |
denotes |
As |
| T28555 |
8601-8605 |
JJ |
denotes |
such |
| T51816 |
8605-8606 |
-COMMA- |
denotes |
, |
| T46678 |
8607-8609 |
PRP |
denotes |
we |
| T91843 |
8610-8619 |
VBD |
denotes |
performed |
| T80993 |
8620-8631 |
NN |
denotes |
mutagenesis |
| T47375 |
8632-8634 |
TO |
denotes |
to |
| T68681 |
8635-8640 |
VB |
denotes |
knock |
| T20175 |
8641-8644 |
RP |
denotes |
out |
| T89961 |
8645-8658 |
NN |
denotes |
glycosylation |
| T13006 |
8659-8664 |
NNS |
denotes |
sites |
| T17100 |
8665-8669 |
IN |
denotes |
with |
| T12886 |
8670-8675 |
NN |
denotes |
N155A |
| T64492 |
8675-8676 |
-COMMA- |
denotes |
, |
| T78169 |
8677-8682 |
NN |
denotes |
N166A |
| T20053 |
8682-8683 |
-COMMA- |
denotes |
, |
| T50640 |
8684-8687 |
CC |
denotes |
and |
| T12106 |
8688-8693 |
NN |
denotes |
N236A |
| T5495 |
8694-8703 |
NNS |
denotes |
mutations |
| T38605 |
8705-8718 |
JJ |
denotes |
Site-specific |
| T73292 |
8719-8727 |
NN |
denotes |
analysis |
| T67434 |
8728-8730 |
IN |
denotes |
of |
| T70835 |
8731-8736 |
DT |
denotes |
these |
| T43617 |
8737-8746 |
NN |
denotes |
glycan-KO |
| T88004 |
8747-8754 |
NNS |
denotes |
mutants |
| T25939 |
8755-8763 |
VBD |
denotes |
revealed |
| T13557 |
8764-8772 |
VBN |
denotes |
enhanced |
| T1670 |
8773-8781 |
NN |
denotes |
trimming |
| T57479 |
8782-8784 |
IN |
denotes |
of |
| T68502 |
8785-8792 |
NN |
denotes |
mannose |
| T91138 |
8793-8801 |
NNS |
denotes |
residues |
| T34347 |
8801-8802 |
-COMMA- |
denotes |
, |
| T48546 |
8803-8807 |
FW |
denotes |
i.e. |
| T76136 |
8808-8817 |
VBN |
denotes |
increased |
| T14034 |
8818-8828 |
NN |
denotes |
processing |
| T78905 |
8828-8829 |
-COMMA- |
denotes |
, |
| T88293 |
8830-8834 |
WRB |
denotes |
when |
| T83202 |
8835-8841 |
NN |
denotes |
glycan |
| T70460 |
8842-8852 |
NN |
denotes |
clustering |
| T30751 |
8853-8856 |
VBD |
denotes |
was |
| T12473 |
8857-8864 |
VBN |
denotes |
reduced |
| T49752 |
8865-8866 |
-LRB- |
denotes |
( |
| T67538 |
8866-8868 |
NN |
denotes |
SI |
| T99013 |
8869-8875 |
NN |
denotes |
Fig. 4 |
| T79420 |
8875-8876 |
-RRB- |
denotes |
) |
| T67059 |
8878-8881 |
DT |
denotes |
The |
| T14141 |
8882-8890 |
NN |
denotes |
presence |
| T95025 |
8891-8893 |
IN |
denotes |
of |
| T69698 |
8894-8903 |
VBN |
denotes |
clustered |
| T70586 |
8904-8921 |
JJ |
denotes |
oligomannose-type |
| T74519 |
8922-8929 |
NNS |
denotes |
glycans |
| T38719 |
8930-8932 |
VBZ |
denotes |
is |
| T19161 |
8933-8944 |
JJ |
denotes |
reminiscent |
| T96776 |
8945-8947 |
IN |
denotes |
of |
| T24985 |
8948-8952 |
DT |
denotes |
that |
| T40354 |
8953-8958 |
VBN |
denotes |
found |
| T8442 |
8959-8961 |
IN |
denotes |
on |
| T27531 |
8962-8967 |
JJ |
denotes |
other |
| T77670 |
8968-8973 |
JJ |
denotes |
viral |
| T91715 |
8974-8987 |
NNS |
denotes |
glycoproteins |
| T67031 |
8987-8988 |
-COMMA- |
denotes |
, |
| T58888 |
8989-8998 |
VBG |
denotes |
including |
| T43383 |
8999-9004 |
NN |
denotes |
HIV-1 |
| T2450 |
9005-9008 |
NN |
denotes |
Env |
| T74217 |
9009-9012 |
CC |
denotes |
and |
| T84923 |
9013-9017 |
NN |
denotes |
LASV |
| T96185 |
9018-9038 |
NN |
denotes |
GPC24,31,34,36,45,46 |
| T18456 |
9040-9044 |
NN |
denotes |
Fig. |
| T38026 |
9045-9046 |
CD |
denotes |
2 |
| T11696 |
9047-9059 |
JJ |
denotes |
Quantitative |
| T81709 |
9060-9073 |
JJ |
denotes |
site-specific |
| T93400 |
9074-9082 |
JJ |
denotes |
N-linked |
| T30000 |
9083-9089 |
NN |
denotes |
glycan |
| T11057 |
9090-9098 |
NN |
denotes |
analysis |
| T72208 |
9099-9101 |
IN |
denotes |
of |
| T91997 |
9102-9106 |
NNS |
denotes |
SARS |
| T44946 |
9107-9110 |
CC |
denotes |
and |
| T46103 |
9111-9115 |
NN |
denotes |
MERS |
| T75132 |
9116-9127 |
NN |
denotes |
coronavirus |
| T95276 |
9128-9133 |
NN |
denotes |
spike |
| T3262 |
9134-9147 |
NNS |
denotes |
glycoproteins |
| T84029 |
9149-9157 |
VBN |
denotes |
Purified |
| T48343 |
9158-9159 |
-LRB- |
denotes |
( |
| T26533 |
9159-9160 |
DT |
denotes |
a |
| T86435 |
9160-9161 |
-RRB- |
denotes |
) |
| T44348 |
9162-9166 |
NNS |
denotes |
MERS |
| T9629 |
9167-9170 |
CC |
denotes |
and |
| T48581 |
9171-9172 |
NN |
denotes |
b |
| T35585 |
9173-9177 |
NNP |
denotes |
SARS |
| T95868 |
9178-9179 |
NN |
denotes |
S |
| T54061 |
9180-9188 |
NNS |
denotes |
proteins |
| T60926 |
9189-9193 |
VBD |
denotes |
were |
| T7737 |
9194-9216 |
JJ |
denotes |
digested. Quantitative |
| T84409 |
9217-9230 |
JJ |
denotes |
site-specific |
| T71906 |
9231-9239 |
JJ |
denotes |
N-linked |
| T31843 |
9240-9246 |
NN |
denotes |
glycan |
| T99530 |
9247-9255 |
NN |
denotes |
analysis |
| T57258 |
9256-9258 |
IN |
denotes |
of |
| T44594 |
9259-9260 |
DT |
denotes |
a |
| T81945 |
9261-9265 |
NN |
denotes |
MERS |
| T17293 |
9266-9269 |
CC |
denotes |
and |
| T47096 |
9270-9271 |
NN |
denotes |
b |
| T88210 |
9272-9276 |
NNP |
denotes |
SARS |
| T89662 |
9277-9278 |
NNP |
denotes |
S |
| T2440 |
9279-9292 |
NNS |
denotes |
glycoproteins |
| T15012 |
9294-9302 |
VBN |
denotes |
Purified |
| T24811 |
9303-9304 |
NN |
denotes |
S |
| T17113 |
9305-9313 |
NNS |
denotes |
proteins |
| T45227 |
9314-9318 |
VBD |
denotes |
were |
| T93138 |
9319-9327 |
VBN |
denotes |
digested |
| T86575 |
9328-9332 |
IN |
denotes |
with |
| T51812 |
9333-9340 |
NN |
denotes |
trypsin |
| T21664 |
9340-9341 |
-COMMA- |
denotes |
, |
| T40461 |
9342-9354 |
NN |
denotes |
chymotrypsin |
| T86817 |
9354-9355 |
-COMMA- |
denotes |
, |
| T72210 |
9356-9367 |
JJ |
denotes |
alpha-lytic |
| T56838 |
9368-9376 |
NN |
denotes |
protease |
| T18984 |
9376-9377 |
-COMMA- |
denotes |
, |
| T43478 |
9378-9383 |
NN |
denotes |
Glu-C |
| T17765 |
9383-9384 |
-COMMA- |
denotes |
, |
| T82693 |
9385-9388 |
CC |
denotes |
and |
| T61553 |
9389-9396 |
NN |
denotes |
trypsin |
| T17900 |
9397-9401 |
CC |
denotes |
plus |
| T8143 |
9402-9414 |
NN |
denotes |
chymotrypsin |
| T72819 |
9414-9415 |
-COMMA- |
denotes |
, |
| T41703 |
9416-9420 |
RB |
denotes |
then |
| T92120 |
9421-9429 |
VBN |
denotes |
analysed |
| T90251 |
9430-9432 |
IN |
denotes |
by |
| T16273 |
9433-9439 |
NN |
denotes |
LC-ESI |
| T68396 |
9440-9442 |
NN |
denotes |
MS |
| T44906 |
9444-9450 |
NN |
denotes |
Glycan |
| T82137 |
9451-9463 |
NNS |
denotes |
compositions |
| T30425 |
9464-9467 |
VBP |
denotes |
are |
| T96908 |
9468-9473 |
VBN |
denotes |
based |
| T54010 |
9474-9476 |
IN |
denotes |
on |
| T48766 |
9477-9480 |
DT |
denotes |
the |
| T91677 |
9481-9487 |
NN |
denotes |
glycan |
| T73464 |
9488-9495 |
NN |
denotes |
library |
| T90139 |
9496-9505 |
VBN |
denotes |
generated |
| T52708 |
9506-9510 |
IN |
denotes |
from |
| T79176 |
9511-9523 |
JJ |
denotes |
negative-ion |
| T47018 |
9524-9528 |
NN |
denotes |
mass |
| T10175 |
9529-9541 |
NN |
denotes |
spectrometry |
| T31210 |
9542-9544 |
IN |
denotes |
of |
| T92018 |
9545-9553 |
VBN |
denotes |
released |
| T52131 |
9554-9563 |
NNS |
denotes |
N-glycans |
| T86682 |
9565-9568 |
DT |
denotes |
The |
| T44329 |
9569-9572 |
NN |
denotes |
bar |
| T14374 |
9573-9579 |
NNS |
denotes |
graphs |
| T64768 |
9580-9589 |
VBP |
denotes |
represent |
| T3818 |
9590-9593 |
DT |
denotes |
the |
| T94495 |
9594-9602 |
JJ |
denotes |
relative |
| T48265 |
9603-9613 |
NNS |
denotes |
quantities |
| T96495 |
9614-9616 |
IN |
denotes |
of |
| T19945 |
9617-9621 |
DT |
denotes |
each |
| T83205 |
9622-9628 |
NN |
denotes |
glycan |
| T29095 |
9629-9634 |
NN |
denotes |
group |
| T55384 |
9635-9639 |
IN |
denotes |
with |
| T66610 |
9640-9657 |
JJ |
denotes |
oligomannose-type |
| T19908 |
9658-9664 |
NN |
denotes |
glycan |
| T86925 |
9665-9671 |
NN |
denotes |
series |
| T92642 |
9672-9673 |
-LRB- |
denotes |
( |
| T83803 |
9673-9675 |
NN |
denotes |
M9 |
| T3618 |
9676-9678 |
TO |
denotes |
to |
| T13438 |
9679-9681 |
NN |
denotes |
M5 |
| T28189 |
9681-9682 |
-SEMICOLON- |
denotes |
; |
| T91020 |
9683-9694 |
NN |
denotes |
Man9GlcNAc2 |
| T50998 |
9695-9697 |
TO |
denotes |
to |
| T81038 |
9698-9709 |
NN |
denotes |
Man5GlcNAc2 |
| T43620 |
9709-9710 |
-RRB- |
denotes |
) |
| T51798 |
9711-9712 |
-LRB- |
denotes |
( |
| T99047 |
9712-9717 |
JJ |
denotes |
green |
| T46694 |
9717-9718 |
-RRB- |
denotes |
) |
| T68800 |
9718-9719 |
-COMMA- |
denotes |
, |
| T39300 |
9720-9732 |
VBN |
denotes |
afucosylated |
| T25055 |
9733-9736 |
CC |
denotes |
and |
| T40035 |
9737-9748 |
VBN |
denotes |
fucosylated |
| T28659 |
9749-9755 |
NN |
denotes |
hybrid |
| T49864 |
9756-9763 |
NNS |
denotes |
glycans |
| T85300 |
9764-9765 |
-LRB- |
denotes |
( |
| T6763 |
9765-9771 |
NNP |
denotes |
Hybrid |
| T31145 |
9772-9773 |
CC |
denotes |
& |
| T19441 |
9774-9775 |
NNP |
denotes |
F |
| T10907 |
9776-9782 |
NNP |
denotes |
Hybrid |
| T44180 |
9782-9783 |
-RRB- |
denotes |
) |
| T33083 |
9784-9785 |
-LRB- |
denotes |
( |
| T64136 |
9785-9791 |
VBN |
denotes |
dashed |
| T25133 |
9792-9796 |
NN |
denotes |
pink |
| T8494 |
9796-9797 |
-RRB- |
denotes |
) |
| T31666 |
9797-9798 |
-COMMA- |
denotes |
, |
| T18761 |
9799-9802 |
CC |
denotes |
and |
| T18896 |
9803-9810 |
JJ |
denotes |
complex |
| T10070 |
9811-9818 |
NNS |
denotes |
glycans |
| T81627 |
9819-9826 |
VBD |
denotes |
grouped |
| T40473 |
9827-9836 |
VBG |
denotes |
according |
| T20923 |
9837-9839 |
TO |
denotes |
to |
| T55810 |
9840-9843 |
DT |
denotes |
the |
| T71311 |
9844-9850 |
NN |
denotes |
number |
| T36859 |
9851-9853 |
IN |
denotes |
of |
| T43194 |
9854-9862 |
NNS |
denotes |
antennae |
| T27706 |
9863-9866 |
CC |
denotes |
and |
| T75366 |
9867-9875 |
NN |
denotes |
presence |
| T12646 |
9876-9878 |
IN |
denotes |
of |
| T91547 |
9879-9883 |
NN |
denotes |
core |
| T95927 |
9884-9896 |
NN |
denotes |
fucosylation |
| T75194 |
9897-9898 |
-LRB- |
denotes |
( |
| T61150 |
9898-9900 |
NN |
denotes |
A1 |
| T11703 |
9901-9903 |
TO |
denotes |
to |
| T84163 |
9904-9907 |
NN |
denotes |
FA4 |
| T52589 |
9907-9908 |
-RRB- |
denotes |
) |
| T3633 |
9909-9910 |
-LRB- |
denotes |
( |
| T70036 |
9910-9914 |
NN |
denotes |
pink |
| T45573 |
9914-9915 |
-RRB- |
denotes |
) |
| T26477 |
9917-9921 |
VBN |
denotes |
Left |
| T2107 |
9922-9924 |
TO |
denotes |
to |
| T54092 |
9925-9930 |
JJ |
denotes |
right |
| T12300 |
9930-9931 |
-SEMICOLON- |
denotes |
; |
| T51881 |
9932-9937 |
JJS |
denotes |
least |
| T18623 |
9938-9947 |
VBN |
denotes |
processed |
| T90503 |
9948-9950 |
TO |
denotes |
to |
| T56324 |
9951-9955 |
RBS |
denotes |
most |
| T7681 |
9956-9965 |
VBN |
denotes |
processed |
| T36496 |
9967-9970 |
DT |
denotes |
The |
| T76280 |
9971-9974 |
NN |
denotes |
pie |
| T23755 |
9975-9981 |
NNS |
denotes |
charts |
| T57945 |
9982-9991 |
VBP |
denotes |
summarise |
| T4038 |
9992-9995 |
DT |
denotes |
the |
| T33045 |
9996-10010 |
NN |
denotes |
quantification |
| T90570 |
10011-10013 |
IN |
denotes |
of |
| T98847 |
10014-10019 |
DT |
denotes |
these |
| T1661 |
10020-10027 |
NNS |
denotes |
glycans |
| T49504 |
10029-10039 |
JJ |
denotes |
Additional |
| T14064 |
10040-10053 |
JJ |
denotes |
compositional |
| T57392 |
10054-10065 |
NN |
denotes |
information |
| T38584 |
10066-10075 |
VBG |
denotes |
regarding |
| T17537 |
10076-10079 |
DT |
denotes |
the |
| T42677 |
10080-10092 |
NN |
denotes |
distribution |
| T43754 |
10093-10095 |
IN |
denotes |
of |
| T2132 |
10096-10108 |
NN |
denotes |
fucosylation |
| T30799 |
10109-10112 |
CC |
denotes |
and |
| T46773 |
10113-10124 |
NN |
denotes |
sialylation |
| T29532 |
10125-10128 |
MD |
denotes |
can |
| T93684 |
10129-10131 |
VB |
denotes |
be |
| T40276 |
10132-10137 |
VBN |
denotes |
found |
| T86408 |
10138-10140 |
IN |
denotes |
in |
| T98608 |
10141-10143 |
NN |
denotes |
SI |
| T42803 |
10144-10150 |
NN |
denotes |
Fig. 3 |
| T66723 |
10152-10156 |
CD |
denotes |
Fig. |
| T49217 |
10157-10158 |
CD |
denotes |
3 |
| T58946 |
10159-10174 |
JJ |
denotes |
Structure-based |
| T75718 |
10175-10182 |
NN |
denotes |
mapping |
| T97068 |
10183-10185 |
IN |
denotes |
of |
| T12761 |
10186-10194 |
JJ |
denotes |
N-linked |
| T25276 |
10195-10202 |
NNS |
denotes |
glycans |
| T53208 |
10203-10205 |
IN |
denotes |
on |
| T64129 |
10206-10210 |
NNS |
denotes |
MERS |
| T13582 |
10211-10214 |
CC |
denotes |
and |
| T84570 |
10215-10219 |
NNP |
denotes |
SARS |
| T16671 |
10220-10221 |
NN |
denotes |
S |
| T75686 |
10222-10230 |
NNS |
denotes |
proteins |
| T33108 |
10232-10235 |
DT |
denotes |
The |
| T5164 |
10236-10245 |
NN |
denotes |
modelling |
| T85081 |
10246-10248 |
IN |
denotes |
of |
| T78202 |
10249-10252 |
DT |
denotes |
the |
| T60050 |
10253-10267 |
RB |
denotes |
experimentally |
| T4820 |
10268-10276 |
VBN |
denotes |
observed |
| T14194 |
10277-10290 |
NN |
denotes |
glycosylation |
| T67945 |
10291-10293 |
VBZ |
denotes |
is |
| T60933 |
10294-10305 |
VBN |
denotes |
illustrated |
| T74928 |
10306-10308 |
IN |
denotes |
on |
| T84730 |
10309-10312 |
DT |
denotes |
the |
| T26156 |
10313-10322 |
NN |
denotes |
prefusion |
| T35915 |
10323-10332 |
NN |
denotes |
structure |
| T38149 |
10333-10335 |
IN |
denotes |
of |
| T82839 |
10336-10344 |
JJ |
denotes |
trimeric |
| T8210 |
10345-10346 |
DT |
denotes |
a |
| T24421 |
10347-10351 |
NN |
denotes |
MERS |
| T35489 |
10352-10353 |
NN |
denotes |
S |
| T78652 |
10354-10355 |
-LRB- |
denotes |
( |
| T68425 |
10355-10358 |
NN |
denotes |
PDB |
| T70607 |
10359-10361 |
NN |
denotes |
ID |
| T28784 |
10362-10366 |
NN |
denotes |
5X59 |
| T45890 |
10366-10367 |
-RRB- |
denotes |
) |
| T7560 |
10367-10373 |
CD |
denotes |
11 and |
| T76185 |
10374-10375 |
NN |
denotes |
b |
| T79009 |
10376-10380 |
NNP |
denotes |
SARS |
| T30776 |
10381-10382 |
NNP |
denotes |
S |
| T73014 |
10383-10384 |
-LRB- |
denotes |
( |
| T68521 |
10384-10387 |
NN |
denotes |
PDB |
| T15706 |
10388-10390 |
NN |
denotes |
ID |
| T11708 |
10391-10395 |
NN |
denotes |
5X58 |
| T3010 |
10395-10396 |
-RRB- |
denotes |
) |
| T27583 |
10396-10430 |
JJ |
denotes |
11 glycoproteins. Structural-based |
| T28741 |
10431-10438 |
NN |
denotes |
mapping |
| T83177 |
10439-10441 |
IN |
denotes |
of |
| T70681 |
10442-10450 |
JJ |
denotes |
N-linked |
| T92110 |
10451-10458 |
NNS |
denotes |
glycans |
| T35748 |
10459-10461 |
IN |
denotes |
on |
| T9158 |
10462-10463 |
DT |
denotes |
a |
| T59935 |
10464-10468 |
NN |
denotes |
MERS |
| T12304 |
10469-10472 |
CC |
denotes |
and |
| T82313 |
10473-10474 |
NN |
denotes |
b |
| T61347 |
10475-10479 |
NNP |
denotes |
SARS |
| T24930 |
10480-10481 |
NNP |
denotes |
S |
| T68640 |
10482-10490 |
NNS |
denotes |
proteins |
| T58506 |
10492-10495 |
DT |
denotes |
The |
| T30217 |
10496-10505 |
NN |
denotes |
modelling |
| T24446 |
10506-10508 |
IN |
denotes |
of |
| T64701 |
10509-10512 |
DT |
denotes |
the |
| T32032 |
10513-10527 |
RB |
denotes |
experimentally |
| T87865 |
10528-10536 |
VBN |
denotes |
observed |
| T41472 |
10537-10550 |
NN |
denotes |
glycosylation |
| T75169 |
10551-10553 |
VBZ |
denotes |
is |
| T85671 |
10554-10565 |
VBN |
denotes |
illustrated |
| T14723 |
10566-10568 |
IN |
denotes |
on |
| T33006 |
10569-10572 |
DT |
denotes |
the |
| T74197 |
10573-10582 |
NN |
denotes |
prefusion |
| T74594 |
10583-10592 |
NN |
denotes |
structure |
| T32963 |
10593-10595 |
IN |
denotes |
of |
| T41739 |
10596-10604 |
JJ |
denotes |
trimeric |
| T10224 |
10605-10609 |
NNS |
denotes |
MERS |
| T21879 |
10610-10611 |
NN |
denotes |
S |
| T97449 |
10612-10613 |
-LRB- |
denotes |
( |
| T53301 |
10613-10616 |
NN |
denotes |
PDB |
| T9349 |
10617-10619 |
NN |
denotes |
ID |
| T99864 |
10620-10624 |
NN |
denotes |
5X59 |
| T96751 |
10624-10625 |
-RRB- |
denotes |
) |
| T41923 |
10625-10627 |
CD |
denotes |
11 |
| T4404 |
10628-10631 |
CC |
denotes |
and |
| T91868 |
10632-10636 |
NNP |
denotes |
SARS |
| T72317 |
10637-10638 |
NNP |
denotes |
S |
| T2448 |
10639-10640 |
-LRB- |
denotes |
( |
| T71010 |
10640-10643 |
NN |
denotes |
PDB |
| T12743 |
10644-10646 |
NN |
denotes |
ID |
| T88079 |
10647-10651 |
NN |
denotes |
5X58 |
| T86576 |
10651-10652 |
-RRB- |
denotes |
) |
| T3017 |
10652-10654 |
CD |
denotes |
11 |
| T99799 |
10655-10668 |
NNS |
denotes |
glycoproteins |
| T93818 |
10670-10673 |
DT |
denotes |
The |
| T88390 |
10674-10681 |
NNS |
denotes |
glycans |
| T27490 |
10682-10685 |
VBP |
denotes |
are |
| T93961 |
10686-10693 |
VBN |
denotes |
colored |
| T72784 |
10694-10703 |
VBG |
denotes |
according |
| T77097 |
10704-10706 |
TO |
denotes |
to |
| T64192 |
10707-10719 |
NN |
denotes |
oligomannose |
| T65168 |
10720-10727 |
NN |
denotes |
content |
| T6760 |
10727-10728 |
-COMMA- |
denotes |
, |
| T9745 |
10729-10731 |
IN |
denotes |
as |
| T86418 |
10732-10739 |
VBN |
denotes |
defined |
| T30404 |
10740-10742 |
IN |
denotes |
by |
| T37495 |
10743-10746 |
DT |
denotes |
the |
| T79747 |
10747-10750 |
NN |
denotes |
key |
| T59664 |
10752-10756 |
NN |
denotes |
DPP4 |
| T85817 |
10757-10773 |
JJ |
denotes |
receptor-binding |
| T40508 |
10774-10779 |
NNS |
denotes |
sites |
| T52910 |
10780-10783 |
CC |
denotes |
and |
| T7086 |
10784-10788 |
NN |
denotes |
ACE2 |
| T75407 |
10789-10805 |
JJ |
denotes |
receptor-binding |
| T46887 |
10806-10811 |
NNS |
denotes |
sites |
| T73267 |
10812-10815 |
IN |
denotes |
for |
| T33037 |
10816-10820 |
NNS |
denotes |
MERS |
| T82290 |
10821-10824 |
CC |
denotes |
and |
| T38470 |
10825-10829 |
NNS |
denotes |
SARS |
| T11920 |
10829-10830 |
-COMMA- |
denotes |
, |
| T13712 |
10831-10843 |
RB |
denotes |
respectively |
| T3547 |
10843-10844 |
-COMMA- |
denotes |
, |
| T34630 |
10845-10848 |
VBP |
denotes |
are |
| T48779 |
10849-10858 |
VBN |
denotes |
indicated |
| T50978 |
10859-10861 |
IN |
denotes |
in |
| T62580 |
10862-10867 |
NN |
denotes |
light |
| T99144 |
10868-10872 |
NN |
denotes |
blue |
| T43036 |
10874-10877 |
DT |
denotes |
The |
| T72864 |
10878-10880 |
NN |
denotes |
S1 |
| T60407 |
10881-10884 |
CC |
denotes |
and |
| T63087 |
10885-10887 |
NN |
denotes |
S2 |
| T35349 |
10888-10896 |
NNS |
denotes |
subunits |
| T29813 |
10897-10900 |
VBP |
denotes |
are |
| T72291 |
10901-10908 |
VBN |
denotes |
colored |
| T28888 |
10909-10914 |
JJ |
denotes |
light |
| T2559 |
10915-10919 |
JJ |
denotes |
grey |
| T24147 |
10920-10923 |
CC |
denotes |
and |
| T73178 |
10924-10928 |
JJ |
denotes |
dark |
| T95495 |
10929-10933 |
NN |
denotes |
grey |
| T87030 |
10933-10934 |
-COMMA- |
denotes |
, |
| T42416 |
10935-10947 |
RB |
denotes |
respectively |
| T86019 |
10949-10953 |
NNP |
denotes |
Fig. |
| T3693 |
10954-10955 |
CD |
denotes |
4 |
| T11619 |
10956-10966 |
JJ |
denotes |
Amino-acid |
| T79527 |
10967-10975 |
NN |
denotes |
sequence |
| T16112 |
10976-10991 |
NN |
denotes |
diversification |
| T17730 |
10992-10998 |
IN |
denotes |
across |
| T51516 |
10999-11003 |
NNS |
denotes |
SARS |
| T64040 |
11004-11007 |
CC |
denotes |
and |
| T54827 |
11008-11012 |
NNS |
denotes |
MERS |
| T40726 |
11013-11019 |
NNS |
denotes |
spikes |
| T4452 |
11021-11022 |
DT |
denotes |
a |
| T8758 |
11023-11033 |
JJ |
denotes |
Amino-acid |
| T82356 |
11034-11043 |
NN |
denotes |
diversity |
| T87134 |
11044-11046 |
IN |
denotes |
in |
| T33615 |
11047-11051 |
NNS |
denotes |
SARS |
| T87940 |
11052-11055 |
CC |
denotes |
and |
| T96992 |
11056-11060 |
NNS |
denotes |
MERS |
| T74428 |
11061-11062 |
NN |
denotes |
S |
| T21364 |
11063-11067 |
NN |
denotes |
gene |
| T75679 |
11068-11077 |
NNS |
denotes |
sequences |
| T91293 |
11079-11087 |
JJ |
denotes |
Averaged |
| T25884 |
11088-11094 |
NNS |
denotes |
values |
| T75654 |
11095-11098 |
IN |
denotes |
for |
| T60028 |
11099-11103 |
DT |
denotes |
each |
| T46478 |
11104-11110 |
NN |
denotes |
domain |
| T85913 |
11111-11114 |
VBP |
denotes |
are |
| T30619 |
11115-11119 |
RB |
denotes |
also |
| T89591 |
11120-11125 |
VBN |
denotes |
shown |
| T64910 |
11126-11132 |
IN |
denotes |
below. |
| T95898 |
11133-11134 |
NN |
denotes |
b |
| T29035 |
11135-11145 |
NN |
denotes |
Comparison |
| T92542 |
11146-11148 |
IN |
denotes |
of |
| T58043 |
11149-11154 |
NN |
denotes |
dN/dS |
| T67622 |
11155-11161 |
NNS |
denotes |
values |
| T30617 |
11162-11169 |
IN |
denotes |
between |
| T22042 |
11170-11176 |
VBN |
denotes |
buried |
| T36252 |
11177-11180 |
CC |
denotes |
and |
| T14068 |
11181-11188 |
VBN |
denotes |
exposed |
| T83973 |
11189-11197 |
NNS |
denotes |
residues |
| T81366 |
11198-11204 |
IN |
denotes |
across |
| T80856 |
11205-11209 |
NNS |
denotes |
SARS |
| T94093 |
11210-11213 |
CC |
denotes |
and |
| T51534 |
11214-11218 |
NN |
denotes |
MERS |
| T9382 |
11219-11220 |
NN |
denotes |
S |
| T63910 |
11221-11222 |
-LRB- |
denotes |
( |
| T13185 |
11222-11228 |
NN |
denotes |
n = 70 |
| T50573 |
11229-11232 |
CC |
denotes |
and |
| T62404 |
11233-11236 |
CD |
denotes |
100 |
| T29922 |
11237-11240 |
IN |
denotes |
for |
| T86628 |
11241-11245 |
NNS |
denotes |
SARS |
| T87992 |
11246-11249 |
CC |
denotes |
and |
| T96551 |
11250-11254 |
NNS |
denotes |
MERS |
| T85872 |
11254-11255 |
-COMMA- |
denotes |
, |
| T62342 |
11256-11268 |
RB |
denotes |
respectively |
| T97022 |
11268-11269 |
-RRB- |
denotes |
) |
| T33742 |
11271-11274 |
DT |
denotes |
The |
| T17721 |
11275-11280 |
NN |
denotes |
error |
| T64712 |
11281-11285 |
NNS |
denotes |
bars |
| T7069 |
11286-11296 |
VBP |
denotes |
correspond |
| T41089 |
11297-11299 |
TO |
denotes |
to |
| T11597 |
11300-11303 |
DT |
denotes |
the |
| T53375 |
11304-11306 |
CD |
denotes |
95 |
| T27417 |
11306-11307 |
NN |
denotes |
% |
| T18198 |
11308-11315 |
JJS |
denotes |
highest |
| T80529 |
11316-11325 |
JJ |
denotes |
posterior |
| T94719 |
11326-11333 |
NN |
denotes |
density |
| T43156 |
11334-11343 |
NNS |
denotes |
intervals |
| T2785 |
11344-11349 |
IN |
denotes |
while |
| T81755 |
11350-11353 |
DT |
denotes |
the |
| T65616 |
11354-11361 |
NNS |
denotes |
circles |
| T83825 |
11362-11370 |
VBP |
denotes |
indicate |
| T80900 |
11371-11375 |
JJ |
denotes |
mean |
| T50642 |
11376-11381 |
NN |
denotes |
dN/dS |
| T43870 |
11382-11389 |
NN |
denotes |
values. |
| T97958 |
11390-11391 |
NN |
denotes |
c |
| T94857 |
11392-11399 |
NN |
denotes |
Mapping |
| T13865 |
11400-11402 |
IN |
denotes |
of |
| T77796 |
11403-11406 |
DT |
denotes |
the |
| T59041 |
11407-11410 |
IN |
denotes |
per |
| T69745 |
11411-11418 |
NN |
denotes |
residue |
| T70132 |
11419-11429 |
JJ |
denotes |
amino-acid |
| T1949 |
11430-11439 |
NN |
denotes |
diversity |
| T35196 |
11440-11445 |
VBN |
denotes |
shown |
| T48789 |
11446-11448 |
IN |
denotes |
in |
| T26990 |
11449-11450 |
NN |
denotes |
A |
| T42572 |
11451-11455 |
IN |
denotes |
onto |
| T79273 |
11456-11459 |
DT |
denotes |
the |
| T68609 |
11460-11470 |
NNS |
denotes |
structures |
| T73775 |
11471-11473 |
IN |
denotes |
of |
| T46831 |
11474-11478 |
NNP |
denotes |
SARS |
| T85214 |
11479-11482 |
CC |
denotes |
and |
| T4847 |
11483-11487 |
NN |
denotes |
MERS |
| T77242 |
11488-11489 |
NN |
denotes |
S |
| T29063 |
11490-11491 |
-LRB- |
denotes |
( |
| T96403 |
11491-11494 |
NN |
denotes |
PDB |
| T2424 |
11495-11497 |
NN |
denotes |
ID |
| T43233 |
11498-11502 |
NN |
denotes |
5X58 |
| T31301 |
11503-11506 |
CC |
denotes |
and |
| T77506 |
11507-11511 |
NN |
denotes |
5X59 |
| T73600 |
11511-11512 |
-COMMA- |
denotes |
, |
| T42948 |
11513-11525 |
RB |
denotes |
respectively |
| T46741 |
11525-11526 |
-RRB- |
denotes |
) |
| T67973 |
11526-11528 |
CD |
denotes |
11 |
| T54383 |
11530-11531 |
NN |
denotes |
S |
| T54985 |
11532-11540 |
NNS |
denotes |
proteins |
| T71503 |
11541-11544 |
VBP |
denotes |
are |
| T68699 |
11545-11554 |
VBN |
denotes |
presented |
| T41652 |
11555-11557 |
IN |
denotes |
as |
| T94309 |
11558-11566 |
NN |
denotes |
backbone |
| T38232 |
11567-11573 |
NNS |
denotes |
traces |
| T35432 |
11574-11578 |
IN |
denotes |
with |
| T7775 |
11579-11587 |
NNS |
denotes |
residues |
| T17162 |
11588-11595 |
VBN |
denotes |
colored |
| T49747 |
11596-11605 |
VBG |
denotes |
according |
| T59844 |
11606-11608 |
TO |
denotes |
to |
| T16213 |
11609-11619 |
JJ |
denotes |
amino-acid |
| T58864 |
11620-11629 |
NN |
denotes |
diversity |
| T92910 |
11631-11639 |
NNS |
denotes |
Residues |
| T14256 |
11640-11644 |
IN |
denotes |
with |
| T40837 |
11645-11653 |
JJ |
denotes |
elevated |
| T80639 |
11654-11663 |
NN |
denotes |
diversity |
| T85890 |
11664-11667 |
VBP |
denotes |
are |
| T71146 |
11668-11675 |
VBN |
denotes |
colored |
| T5339 |
11676-11678 |
IN |
denotes |
in |
| T28847 |
11679-11682 |
JJ |
denotes |
red |
| T85163 |
11682-11683 |
-COMMA- |
denotes |
, |
| T69312 |
11684-11687 |
CC |
denotes |
and |
| T87041 |
11688-11696 |
VBN |
denotes |
N-linked |
| T76860 |
11697-11704 |
NNS |
denotes |
glycans |
| T24256 |
11705-11708 |
VBP |
denotes |
are |
| T12192 |
11709-11718 |
VBN |
denotes |
presented |
| T65467 |
11719-11721 |
IN |
denotes |
as |
| T23895 |
11722-11727 |
JJ |
denotes |
white |
| T99373 |
11728-11736 |
NNS |
denotes |
surfaces |
| T72420 |
11738-11751 |
RB |
denotes |
Interestingly |
| T27935 |
11751-11752 |
-COMMA- |
denotes |
, |
| T18688 |
11753-11757 |
NN |
denotes |
SARS |
| T54076 |
11758-11761 |
CC |
denotes |
and |
| T91777 |
11762-11766 |
NN |
denotes |
HKU1 |
| T82660 |
11767-11768 |
-LRB- |
denotes |
( |
| T80158 |
11768-11770 |
NN |
denotes |
SI |
| T18287 |
11771-11777 |
NN |
denotes |
Fig. 2 |
| T26450 |
11777-11778 |
-RRB- |
denotes |
) |
| T22664 |
11779-11780 |
NN |
denotes |
S |
| T70221 |
11781-11789 |
NNS |
denotes |
proteins |
| T8587 |
11790-11793 |
VBD |
denotes |
did |
| T40209 |
11794-11797 |
RB |
denotes |
not |
| T90081 |
11798-11805 |
VB |
denotes |
exhibit |
| T47005 |
11806-11814 |
JJ |
denotes |
specific |
| T66164 |
11815-11822 |
NN |
denotes |
mannose |
| T5302 |
11823-11831 |
NNS |
denotes |
clusters |
| T65310 |
11832-11836 |
WDT |
denotes |
that |
| T95555 |
11837-11847 |
VBP |
denotes |
contribute |
| T21512 |
11848-11850 |
TO |
denotes |
to |
| T23601 |
11851-11854 |
DT |
denotes |
the |
| T71479 |
11855-11862 |
JJ |
denotes |
overall |
| T61001 |
11863-11870 |
NN |
denotes |
mannose |
| T26227 |
11871-11880 |
NN |
denotes |
abundance |
| T25050 |
11880-11881 |
-COMMA- |
denotes |
, |
| T74525 |
11882-11885 |
CC |
denotes |
but |
| T56258 |
11886-11890 |
RB |
denotes |
only |
| T89329 |
11891-11899 |
VBN |
denotes |
isolated |
| T54715 |
11900-11907 |
NNS |
denotes |
glycans |
| T15304 |
11908-11912 |
VBD |
denotes |
were |
| T81576 |
11913-11927 |
VBN |
denotes |
underprocessed |
| T37031 |
11929-11931 |
PRP |
denotes |
We |
| T11037 |
11932-11941 |
VBP |
denotes |
speculate |
| T78740 |
11942-11946 |
IN |
denotes |
that |
| T57941 |
11947-11950 |
DT |
denotes |
the |
| T83472 |
11951-11968 |
JJ |
denotes |
oligomannose-type |
| T62928 |
11969-11976 |
NNS |
denotes |
glycans |
| T41459 |
11977-11981 |
RB |
denotes |
here |
| T13983 |
11982-11987 |
VBP |
denotes |
arise |
| T30720 |
11988-11992 |
IN |
denotes |
from |
| T96574 |
11993-12009 |
JJ |
denotes |
protein-directed |
| T55170 |
12010-12020 |
NN |
denotes |
inhibition |
| T33234 |
12021-12023 |
IN |
denotes |
of |
| T39535 |
12024-12030 |
NN |
denotes |
glycan |
| T17864 |
12031-12041 |
NN |
denotes |
processing |
| T15475 |
12041-12042 |
-COMMA- |
denotes |
, |
| T10659 |
12043-12045 |
IN |
denotes |
as |
| T1566 |
12046-12053 |
VBN |
denotes |
opposed |
| T58559 |
12054-12056 |
TO |
denotes |
to |
| T23943 |
12057-12060 |
DT |
denotes |
the |
| T52429 |
12061-12078 |
JJ |
denotes |
glycan-influenced |
| T84994 |
12079-12089 |
NN |
denotes |
processing |
| T28395 |
12090-12098 |
VBN |
denotes |
observed |
| T8259 |
12099-12101 |
IN |
denotes |
on |
| T19314 |
12102-12106 |
NNS |
denotes |
MERS |
| T3743 |
12108-12119 |
RB |
denotes |
Importantly |
| T69555 |
12119-12120 |
-COMMA- |
denotes |
, |
| T70877 |
12121-12138 |
JJ |
denotes |
oligomannose-type |
| T68539 |
12139-12146 |
NNS |
denotes |
glycans |
| T79414 |
12147-12150 |
VBZ |
denotes |
has |
| T32823 |
12151-12155 |
RB |
denotes |
also |
| T22023 |
12156-12160 |
VBN |
denotes |
been |
| T1963 |
12161-12171 |
VBN |
denotes |
implicated |
| T31422 |
12172-12174 |
IN |
denotes |
in |
| T32938 |
12175-12181 |
JJ |
denotes |
innate |
| T8288 |
12182-12188 |
JJ |
denotes |
immune |
| T72195 |
12189-12200 |
NN |
denotes |
recognition |
| T78182 |
12201-12203 |
IN |
denotes |
of |
| T13186 |
12204-12217 |
NNS |
denotes |
coronaviruses |
| T90164 |
12218-12220 |
IN |
denotes |
by |
| T84232 |
12221-12233 |
NN |
denotes |
lectins47,48 |
| T65100 |
12234-12238 |
WDT |
denotes |
that |
| T10378 |
12239-12248 |
VBP |
denotes |
recognise |
| T13519 |
12249-12254 |
DT |
denotes |
these |
| T42882 |
12255-12269 |
VBN |
denotes |
underprocessed |
| T52825 |
12270-12277 |
NNS |
denotes |
glycans |
| T46370 |
12278-12280 |
IN |
denotes |
as |
| T72183 |
12281-12300 |
JJ |
denotes |
pathogen-associated |
| T32276 |
12301-12310 |
JJ |
denotes |
molecular |
| T39921 |
12311-12319 |
NNS |
denotes |
patterns |
| T46731 |
12321-12326 |
VBN |
denotes |
Given |
| T24648 |
12327-12331 |
IN |
denotes |
that |
| T45765 |
12332-12335 |
DT |
denotes |
the |
| T56881 |
12336-12352 |
JJ |
denotes |
receptor-binding |
| T98112 |
12353-12359 |
NN |
denotes |
domain |
| T74716 |
12360-12362 |
VBZ |
denotes |
is |
| T85598 |
12363-12366 |
DT |
denotes |
the |
| T16051 |
12367-12371 |
JJ |
denotes |
main |
| T58379 |
12372-12378 |
NN |
denotes |
target |
| T53325 |
12379-12381 |
IN |
denotes |
of |
| T7859 |
12382-12394 |
VBG |
denotes |
neutralising |
| T26958 |
12395-12406 |
NN |
denotes |
antibodies8 |
| T7334 |
12406-12407 |
-COMMA- |
denotes |
, |
| T85070 |
12408-12410 |
PRP |
denotes |
it |
| T1822 |
12411-12413 |
VBZ |
denotes |
is |
| T40337 |
12414-12424 |
JJ |
denotes |
surprising |
| T90378 |
12425-12429 |
IN |
denotes |
that |
| T34257 |
12430-12433 |
DT |
denotes |
the |
| T66548 |
12434-12438 |
NN |
denotes |
DPP4 |
| T75367 |
12439-12455 |
JJ |
denotes |
receptor-binding |
| T76130 |
12456-12460 |
NN |
denotes |
site |
| T72556 |
12461-12463 |
IN |
denotes |
of |
| T49036 |
12464-12468 |
NNS |
denotes |
MERS |
| T45911 |
12469-12470 |
NN |
denotes |
S |
| T21250 |
12471-12474 |
VBD |
denotes |
was |
| T8376 |
12475-12478 |
RB |
denotes |
not |
| T2696 |
12479-12487 |
VBN |
denotes |
occluded |
| T90865 |
12488-12490 |
IN |
denotes |
by |
| T29223 |
12491-12498 |
NNS |
denotes |
glycans |
| T85418 |
12499-12500 |
-LRB- |
denotes |
( |
| T83410 |
12500-12507 |
NN |
denotes |
Fig. 3a |
| T92859 |
12507-12508 |
-RRB- |
denotes |
) |
| T98108 |
12508-12509 |
-COMMA- |
denotes |
, |
| T94718 |
12510-12512 |
IN |
denotes |
as |
| T75995 |
12513-12521 |
VBN |
denotes |
observed |
| T33346 |
12522-12525 |
IN |
denotes |
for |
| T37727 |
12526-12531 |
JJ |
denotes |
other |
| T65600 |
12532-12548 |
JJ |
denotes |
receptor-binding |
| T6494 |
12549-12554 |
NNS |
denotes |
sites |
| T57622 |
12555-12557 |
IN |
denotes |
of |
| T15659 |
12558-12563 |
NN |
denotes |
class |
| T77211 |
12564-12565 |
CD |
denotes |
I |
| T77114 |
12566-12571 |
JJ |
denotes |
viral |
| T21676 |
12572-12578 |
NN |
denotes |
fusion |
| T55295 |
12579-12587 |
NNS |
denotes |
proteins |
| T74940 |
12587-12588 |
-COMMA- |
denotes |
, |
| T82828 |
12589-12598 |
VBG |
denotes |
including |
| T94991 |
12599-12603 |
NNP |
denotes |
SARS |
| T30576 |
12604-12605 |
NNP |
denotes |
S |
| T72214 |
12606-12607 |
-LRB- |
denotes |
( |
| T78031 |
12607-12614 |
NN |
denotes |
Fig. 3b |
| T67457 |
12614-12615 |
-RRB- |
denotes |
) |
| T6464 |
12615-12616 |
-COMMA- |
denotes |
, |
| T4572 |
12617-12622 |
NN |
denotes |
HIV-1 |
| T27072 |
12623-12628 |
NN |
denotes |
Env49 |
| T51710 |
12628-12629 |
-COMMA- |
denotes |
, |
| T37781 |
12630-12634 |
NN |
denotes |
LASV |
| T43889 |
12635-12640 |
NN |
denotes |
GPC24 |
| T95596 |
12641-12644 |
CC |
denotes |
and |
| T81584 |
12645-12654 |
NN |
denotes |
influenza |
| T23338 |
12655-12659 |
NN |
denotes |
HA50 |
| T38368 |
12661-12663 |
PRP |
denotes |
We |
| T7627 |
12664-12671 |
VBP |
denotes |
suggest |
| T64380 |
12672-12676 |
IN |
denotes |
that |
| T64096 |
12677-12681 |
DT |
denotes |
this |
| T56477 |
12682-12684 |
VBZ |
denotes |
is |
| T19767 |
12685-12691 |
RB |
denotes |
likely |
| T70981 |
12692-12695 |
JJ |
denotes |
due |
| T34848 |
12696-12698 |
TO |
denotes |
to |
| T31069 |
12699-12702 |
DT |
denotes |
the |
| T33383 |
12703-12712 |
JJ |
denotes |
intrinsic |
| T53788 |
12713-12726 |
NN |
denotes |
functionality |
| T92413 |
12727-12729 |
IN |
denotes |
of |
| T48963 |
12730-12733 |
DT |
denotes |
the |
| T14314 |
12734-12750 |
JJ |
denotes |
receptor-binding |
| T65172 |
12751-12757 |
NN |
denotes |
domain |
| T24472 |
12758-12760 |
IN |
denotes |
of |
| T66405 |
12761-12765 |
NNP |
denotes |
MERS |
| T3759 |
12766-12767 |
NNP |
denotes |
S |
| T35971 |
12767-12768 |
-COMMA- |
denotes |
, |
| T63119 |
12769-12773 |
WDT |
denotes |
that |
| T19398 |
12774-12779 |
MD |
denotes |
would |
| T5062 |
12780-12782 |
VB |
denotes |
be |
| T26453 |
12783-12793 |
RB |
denotes |
sterically |
| T99830 |
12794-12802 |
VBN |
denotes |
hindered |
| T79196 |
12803-12805 |
IN |
denotes |
by |
| T29715 |
12806-12809 |
DT |
denotes |
the |
| T15993 |
12810-12818 |
NN |
denotes |
presence |
| T46581 |
12819-12821 |
IN |
denotes |
of |
| T41531 |
12822-12830 |
JJ |
denotes |
N-linked |
| T84168 |
12831-12838 |
NNS |
denotes |
glycans |
| T31775 |
12838-12839 |
-COMMA- |
denotes |
, |
| T73121 |
12840-12847 |
IN |
denotes |
whereas |
| T8489 |
12848-12853 |
JJ |
denotes |
other |
| T86129 |
12854-12861 |
NNS |
denotes |
viruses |
| T10448 |
12862-12865 |
VBP |
denotes |
are |
| T85155 |
12866-12870 |
JJ |
denotes |
able |
| T10897 |
12871-12873 |
TO |
denotes |
to |
| T93372 |
12874-12885 |
VB |
denotes |
accommodate |
| T42685 |
12886-12889 |
DT |
denotes |
the |
| T16612 |
12890-12908 |
JJ |
denotes |
post-translational |
| T29096 |
12909-12922 |
NNS |
denotes |
modifications |
| T68645 |
12922-12923 |
-COMMA- |
denotes |
, |
| T93438 |
12924-12931 |
IN |
denotes |
without |
| T18466 |
12932-12939 |
RB |
denotes |
greatly |
| T85948 |
12940-12950 |
VBG |
denotes |
perturbing |
| T35584 |
12951-12964 |
NN |
denotes |
functionality |
| T9810 |
12967-12975 |
NN |
denotes |
Sequence |
| T60681 |
12976-12991 |
NN |
denotes |
diversification |
| T14534 |
12992-12994 |
IN |
denotes |
of |
| T70071 |
12995-12998 |
NN |
denotes |
CoV |
| T46208 |
12999-13005 |
NNS |
denotes |
spikes |
| T65633 |
13006-13008 |
PRP |
denotes |
We |
| T71210 |
13009-13021 |
VBD |
denotes |
hypothesized |
| T65773 |
13022-13026 |
IN |
denotes |
that |
| T55109 |
13027-13045 |
JJ |
denotes |
solvent-accessible |
| T1585 |
13045-13046 |
-COMMA- |
denotes |
, |
| T39672 |
13047-13057 |
JJ |
denotes |
amino-acid |
| T20594 |
13058-13066 |
NNS |
denotes |
residues |
| T55010 |
13067-13069 |
IN |
denotes |
on |
| T92344 |
13070-13071 |
NN |
denotes |
S |
| T27449 |
13072-13080 |
NNS |
denotes |
proteins |
| T7753 |
13081-13086 |
MD |
denotes |
would |
| T87805 |
13087-13089 |
VB |
denotes |
be |
| T76109 |
13090-13100 |
VBG |
denotes |
undergoing |
| T49022 |
13101-13107 |
JJR |
denotes |
higher |
| T38215 |
13108-13113 |
NNS |
denotes |
rates |
| T48007 |
13114-13116 |
IN |
denotes |
of |
| T86087 |
13117-13126 |
NNS |
denotes |
mutations |
| T52952 |
13127-13135 |
VBN |
denotes |
compared |
| T99241 |
13136-13140 |
IN |
denotes |
with |
| T30950 |
13141-13147 |
JJ |
denotes |
buried |
| T25052 |
13148-13156 |
NNS |
denotes |
residues |
| T46492 |
13157-13160 |
CC |
denotes |
and |
| T57528 |
13161-13168 |
NNS |
denotes |
regions |
| T50177 |
13169-13173 |
WDT |
denotes |
that |
| T46892 |
13174-13177 |
VBP |
denotes |
are |
| T25102 |
13178-13186 |
VBN |
denotes |
occluded |
| T44481 |
13187-13189 |
IN |
denotes |
by |
| T18790 |
13190-13197 |
NNS |
denotes |
glycans |
| T48178 |
13197-13198 |
-COMMA- |
denotes |
, |
| T59110 |
13199-13204 |
WDT |
denotes |
which |
| T61432 |
13205-13208 |
VBP |
denotes |
are |
| T59632 |
13209-13215 |
JJ |
denotes |
unable |
| T87545 |
13216-13218 |
TO |
denotes |
to |
| T66630 |
13219-13221 |
VB |
denotes |
be |
| T30435 |
13222-13230 |
VBN |
denotes |
targeted |
| T87263 |
13231-13233 |
IN |
denotes |
by |
| T84547 |
13234-13238 |
NN |
denotes |
host |
| T42560 |
13239-13245 |
JJ |
denotes |
immune |
| T4934 |
13246-13255 |
NNS |
denotes |
responses |
| T73202 |
13257-13259 |
TO |
denotes |
To |
| T86654 |
13260-13264 |
DT |
denotes |
that |
| T62840 |
13265-13268 |
NN |
denotes |
end |
| T60967 |
13268-13269 |
-COMMA- |
denotes |
, |
| T58857 |
13270-13272 |
PRP |
denotes |
we |
| T3483 |
13273-13282 |
VBD |
denotes |
performed |
| T44308 |
13283-13285 |
DT |
denotes |
an |
| T42487 |
13286-13296 |
NN |
denotes |
evaluation |
| T38057 |
13297-13299 |
IN |
denotes |
of |
| T40313 |
13300-13310 |
JJ |
denotes |
amino-acid |
| T79756 |
13311-13326 |
NN |
denotes |
diversification |
| T74853 |
13327-13329 |
IN |
denotes |
on |
| T83914 |
13330-13331 |
DT |
denotes |
a |
| T53700 |
13332-13348 |
JJ |
denotes |
residue-specific |
| T63979 |
13349-13354 |
NN |
denotes |
level |
| T62380 |
13354-13355 |
-COMMA- |
denotes |
, |
| T6148 |
13356-13361 |
VBG |
denotes |
using |
| T77953 |
13362-13370 |
RB |
denotes |
publicly |
| T27779 |
13371-13380 |
JJ |
denotes |
available |
| T83161 |
13381-13385 |
NN |
denotes |
gene |
| T25304 |
13386-13395 |
NNS |
denotes |
sequences |
| T83245 |
13396-13398 |
IN |
denotes |
of |
| T52371 |
13399-13403 |
NNP |
denotes |
SARS |
| T61083 |
13404-13407 |
CC |
denotes |
and |
| T72419 |
13408-13412 |
NNP |
denotes |
MERS |
| T42372 |
13413-13414 |
NNP |
denotes |
S |
| T3167 |
13414-13415 |
-COMMA- |
denotes |
, |
| T70472 |
13416-13421 |
WDT |
denotes |
which |
| T16556 |
13422-13425 |
VBD |
denotes |
was |
| T69286 |
13426-13436 |
VBN |
denotes |
calculated |
| T52989 |
13437-13439 |
IN |
denotes |
as |
| T29326 |
13440-13443 |
DT |
denotes |
the |
| T41479 |
13444-13450 |
NN |
denotes |
number |
| T1834 |
13451-13453 |
IN |
denotes |
of |
| T51205 |
13454-13462 |
VBN |
denotes |
observed |
| T91746 |
13463-13471 |
JJ |
denotes |
pairwise |
| T46357 |
13472-13483 |
NNS |
denotes |
differences |
| T17558 |
13484-13491 |
VBN |
denotes |
divided |
| T41351 |
13492-13494 |
IN |
denotes |
by |
| T50799 |
13495-13498 |
DT |
denotes |
the |
| T28579 |
13499-13504 |
JJ |
denotes |
total |
| T58945 |
13505-13511 |
NN |
denotes |
number |
| T84292 |
13512-13514 |
IN |
denotes |
of |
| T34101 |
13515-13523 |
JJ |
denotes |
pairwise |
| T94055 |
13524-13535 |
NNS |
denotes |
comparisons |
| T18701 |
13537-13544 |
RB |
denotes |
Firstly |
| T74266 |
13544-13545 |
-COMMA- |
denotes |
, |
| T36827 |
13546-13548 |
PRP |
denotes |
we |
| T39186 |
13549-13554 |
VBD |
denotes |
found |
| T6773 |
13555-13559 |
IN |
denotes |
that |
| T13224 |
13560-13570 |
JJ |
denotes |
amino-acid |
| T54008 |
13571-13580 |
NN |
denotes |
diversity |
| T35302 |
13581-13584 |
VBD |
denotes |
was |
| T93591 |
13585-13593 |
VBN |
denotes |
elevated |
| T90961 |
13594-13596 |
IN |
denotes |
at |
| T69090 |
13597-13602 |
VBN |
denotes |
known |
| T86793 |
13603-13611 |
NNS |
denotes |
epitopes |
| T61088 |
13612-13620 |
VBN |
denotes |
targeted |
| T53019 |
13621-13623 |
IN |
denotes |
by |
| T30461 |
13624-13636 |
VBG |
denotes |
neutralizing |
| T32200 |
13637-13647 |
NNS |
denotes |
antibodies |
| T83554 |
13647-13648 |
-COMMA- |
denotes |
, |
| T32640 |
13649-13653 |
JJ |
denotes |
such |
| T51281 |
13654-13656 |
IN |
denotes |
as |
| T69890 |
13657-13660 |
DT |
denotes |
the |
| T83248 |
13661-13671 |
JJ |
denotes |
N-terminal |
| T49099 |
13672-13678 |
NN |
denotes |
domain |
| T58919 |
13679-13682 |
CC |
denotes |
and |
| T18721 |
13683-13686 |
DT |
denotes |
the |
| T18570 |
13687-13703 |
JJ |
denotes |
receptor-binding |
| T60790 |
13704-13711 |
NNS |
denotes |
domains |
| T18812 |
13711-13712 |
-COMMA- |
denotes |
, |
| T96660 |
13713-13716 |
CC |
denotes |
and |
| T11216 |
13717-13724 |
VBN |
denotes |
reduced |
| T27277 |
13725-13727 |
IN |
denotes |
in |
| T89562 |
13728-13731 |
DT |
denotes |
the |
| T7777 |
13732-13739 |
NNS |
denotes |
regions |
| T23472 |
13740-13742 |
IN |
denotes |
in |
| T66095 |
13743-13746 |
DT |
denotes |
the |
| T52990 |
13747-13749 |
NN |
denotes |
S2 |
| T69246 |
13750-13756 |
NN |
denotes |
domain |
| T76095 |
13756-13757 |
-COMMA- |
denotes |
, |
| T33023 |
13758-13762 |
JJ |
denotes |
such |
| T94778 |
13763-13765 |
IN |
denotes |
as |
| T12698 |
13766-13769 |
DT |
denotes |
the |
| T82633 |
13770-13776 |
NN |
denotes |
fusion |
| T75213 |
13777-13784 |
NN |
denotes |
peptide |
| T29294 |
13784-13785 |
-COMMA- |
denotes |
, |
| T28968 |
13786-13792 |
NN |
denotes |
heptad |
| T29760 |
13793-13799 |
NN |
denotes |
repeat |
| T53742 |
13800-13803 |
CD |
denotes |
one |
| T18725 |
13803-13804 |
-COMMA- |
denotes |
, |
| T43420 |
13805-13808 |
CC |
denotes |
and |
| T34460 |
13809-13812 |
DT |
denotes |
the |
| T26621 |
13813-13820 |
JJ |
denotes |
central |
| T91466 |
13821-13826 |
NN |
denotes |
helix |
| T93319 |
13827-13834 |
NNS |
denotes |
domains |
| T88231 |
13834-13835 |
-COMMA- |
denotes |
, |
| T49934 |
13836-13841 |
WDT |
denotes |
which |
| T23715 |
13842-13845 |
VBP |
denotes |
are |
| T33407 |
13846-13852 |
RB |
denotes |
likely |
| T88882 |
13853-13860 |
JJ |
denotes |
subject |
| T76117 |
13861-13863 |
TO |
denotes |
to |
| T4874 |
13864-13871 |
JJR |
denotes |
greater |
| T38302 |
13872-13882 |
JJ |
denotes |
functional |
| T99472 |
13883-13894 |
NNS |
denotes |
constraints |
| T34520 |
13895-13896 |
-LRB- |
denotes |
( |
| T48991 |
13896-13903 |
NN |
denotes |
Fig. 4a |
| T5319 |
13903-13904 |
-RRB- |
denotes |
) |
| T69499 |
13906-13914 |
NN |
denotes |
Analysis |
| T65163 |
13915-13917 |
IN |
denotes |
of |
| T23395 |
13918-13921 |
DT |
denotes |
the |
| T78947 |
13922-13930 |
JJ |
denotes |
relative |
| T61369 |
13931-13936 |
NN |
denotes |
ratio |
| T85886 |
13937-13939 |
IN |
denotes |
of |
| T53309 |
13940-13954 |
JJ |
denotes |
non-synonymous |
| T78726 |
13955-13957 |
TO |
denotes |
to |
| T13118 |
13958-13968 |
JJ |
denotes |
synonymous |
| T63573 |
13969-13979 |
NN |
denotes |
nucleotide |
| T72369 |
13980-13993 |
NNS |
denotes |
substitutions |
| T18378 |
13994-13995 |
-LRB- |
denotes |
( |
| T58404 |
13995-13999 |
FW |
denotes |
i.e. |
| T58779 |
14000-14005 |
NN |
denotes |
dN/dS |
| T10324 |
14006-14012 |
NNS |
denotes |
ratios |
| T30580 |
14012-14013 |
-RRB- |
denotes |
) |
| T83087 |
14014-14022 |
VBD |
denotes |
revealed |
| T2494 |
14023-14027 |
IN |
denotes |
that |
| T4328 |
14028-14035 |
VBN |
denotes |
exposed |
| T12652 |
14036-14044 |
NNS |
denotes |
residues |
| T92287 |
14045-14054 |
VBD |
denotes |
exhibited |
| T88501 |
14055-14068 |
RB |
denotes |
significantly |
| T11718 |
14069-14075 |
JJR |
denotes |
higher |
| T86795 |
14076-14081 |
NN |
denotes |
dN/dS |
| T59603 |
14082-14088 |
NNS |
denotes |
values |
| T7211 |
14089-14090 |
-LRB- |
denotes |
( |
| T4769 |
14090-14097 |
NN |
denotes |
Fig. 4b |
| T47239 |
14097-14098 |
-RRB- |
denotes |
) |
| T90969 |
14100-14106 |
VBN |
denotes |
Buried |
| T92849 |
14107-14115 |
NNS |
denotes |
residues |
| T78244 |
14116-14118 |
IN |
denotes |
on |
| T54331 |
14119-14123 |
NNS |
denotes |
SARS |
| T42940 |
14124-14127 |
VBD |
denotes |
had |
| T56294 |
14128-14132 |
JJ |
denotes |
mean |
| T46802 |
14133-14138 |
NN |
denotes |
dN/dS |
| T64331 |
14139-14145 |
NNS |
denotes |
ratios |
| T35591 |
14146-14148 |
IN |
denotes |
of |
| T4586 |
14149-14153 |
CD |
denotes |
0.31 |
| T68155 |
14154-14162 |
VBN |
denotes |
compared |
| T78948 |
14163-14167 |
IN |
denotes |
with |
| T78585 |
14168-14172 |
CD |
denotes |
2.82 |
| T27968 |
14173-14176 |
IN |
denotes |
for |
| T96310 |
14177-14184 |
VBN |
denotes |
exposed |
| T43288 |
14185-14192 |
NNS |
denotes |
resides |
| T92960 |
14194-14202 |
RB |
denotes |
Likewise |
| T14475 |
14202-14203 |
-COMMA- |
denotes |
, |
| T32298 |
14204-14207 |
DT |
denotes |
the |
| T12634 |
14208-14214 |
VBN |
denotes |
buried |
| T80500 |
14215-14223 |
NNS |
denotes |
residues |
| T77635 |
14224-14226 |
IN |
denotes |
on |
| T24392 |
14227-14231 |
NNS |
denotes |
MERS |
| T2961 |
14232-14235 |
VBD |
denotes |
had |
| T6521 |
14236-14237 |
DT |
denotes |
a |
| T8471 |
14238-14248 |
VBN |
denotes |
calculated |
| T37460 |
14249-14254 |
NN |
denotes |
dN/dS |
| T55408 |
14255-14260 |
NN |
denotes |
ratio |
| T45120 |
14261-14263 |
IN |
denotes |
of |
| T23381 |
14264-14268 |
CD |
denotes |
0.10 |
| T30445 |
14269-14277 |
VBN |
denotes |
compared |
| T55016 |
14278-14282 |
IN |
denotes |
with |
| T1385 |
14283-14290 |
VBN |
denotes |
exposed |
| T65828 |
14291-14299 |
NNS |
denotes |
residues |
| T35353 |
14300-14304 |
IN |
denotes |
with |
| T91154 |
14305-14306 |
DT |
denotes |
a |
| T26380 |
14307-14312 |
NN |
denotes |
value |
| T92544 |
14313-14315 |
IN |
denotes |
of |
| T79406 |
14316-14320 |
CD |
denotes |
0.45 |
| T92418 |
14322-14333 |
RB |
denotes |
Furthermore |
| T91452 |
14333-14334 |
-COMMA- |
denotes |
, |
| T84302 |
14335-14339 |
WRB |
denotes |
when |
| T74584 |
14340-14348 |
JJ |
denotes |
per-site |
| T76352 |
14349-14359 |
JJ |
denotes |
amino-acid |
| T98451 |
14360-14371 |
NNS |
denotes |
diversities |
| T72837 |
14372-14376 |
VBD |
denotes |
were |
| T54724 |
14377-14383 |
VBN |
denotes |
mapped |
| T45778 |
14384-14388 |
IN |
denotes |
onto |
| T98923 |
14389-14392 |
DT |
denotes |
the |
| T59533 |
14393-14398 |
RB |
denotes |
fully |
| T25862 |
14399-14411 |
VBN |
denotes |
glycosylated |
| T32515 |
14412-14422 |
JJ |
denotes |
structural |
| T94405 |
14423-14428 |
NN |
denotes |
model |
| T76643 |
14429-14431 |
IN |
denotes |
of |
| T13755 |
14432-14435 |
DT |
denotes |
the |
| T14482 |
14436-14446 |
JJ |
denotes |
respective |
| T65032 |
14447-14450 |
NN |
denotes |
CoV |
| T12704 |
14451-14452 |
NN |
denotes |
S |
| T70323 |
14453-14461 |
NNS |
denotes |
proteins |
| T33888 |
14462-14463 |
-LRB- |
denotes |
( |
| T60190 |
14463-14470 |
NN |
denotes |
Fig. 4c |
| T27628 |
14470-14471 |
-RRB- |
denotes |
) |
| T87038 |
14471-14472 |
-COMMA- |
denotes |
, |
| T49843 |
14473-14481 |
NNS |
denotes |
hotspots |
| T77547 |
14482-14484 |
IN |
denotes |
of |
| T63244 |
14485-14494 |
NNS |
denotes |
mutations |
| T5765 |
14495-14499 |
VBD |
denotes |
were |
| T8574 |
14500-14511 |
VBN |
denotes |
highlighted |
| T21020 |
14512-14514 |
IN |
denotes |
on |
| T89986 |
14515-14518 |
DT |
denotes |
the |
| T65568 |
14519-14526 |
NN |
denotes |
protein |
| T63130 |
14527-14534 |
NN |
denotes |
surface |
| T96535 |
14535-14545 |
IN |
denotes |
throughout |
| T21467 |
14546-14549 |
DT |
denotes |
the |
| T66745 |
14550-14556 |
NN |
denotes |
trimer |
| T45284 |
14557-14566 |
VBG |
denotes |
revealing |
| T17381 |
14567-14576 |
JJ |
denotes |
extensive |
| T55156 |
14577-14592 |
NNS |
denotes |
vulnerabilities |
| T13067 |
14593-14603 |
VBG |
denotes |
permeating |
| T40910 |
14604-14611 |
IN |
denotes |
through |
| T14483 |
14612-14615 |
DT |
denotes |
the |
| T29556 |
14616-14622 |
NN |
denotes |
glycan |
| T94871 |
14623-14629 |
NN |
denotes |
shield |
| T71413 |
14630-14632 |
IN |
denotes |
of |
| T81413 |
14633-14637 |
NNS |
denotes |
SARS |
| T68523 |
14638-14641 |
CC |
denotes |
and |
| T70297 |
14642-14646 |
NNP |
denotes |
MERS |
| T12679 |
14647-14651 |
NNP |
denotes |
CoVs |
| T87216 |
14653-14655 |
PRP |
denotes |
It |
| T15902 |
14656-14658 |
VBZ |
denotes |
is |
| T6523 |
14659-14670 |
JJ |
denotes |
interesting |
| T19232 |
14671-14673 |
TO |
denotes |
to |
| T97839 |
14674-14678 |
VB |
denotes |
note |
| T99309 |
14679-14682 |
DT |
denotes |
the |
| T40498 |
14683-14687 |
NN |
denotes |
lack |
| T81866 |
14688-14690 |
IN |
denotes |
of |
| T9331 |
14691-14701 |
JJ |
denotes |
amino-acid |
| T44303 |
14702-14711 |
NN |
denotes |
diversity |
| T83531 |
14712-14714 |
IN |
denotes |
on |
| T76133 |
14715-14718 |
DT |
denotes |
the |
| T29918 |
14719-14735 |
JJ |
denotes |
receptor-binding |
| T15412 |
14736-14743 |
NNS |
denotes |
domains |
| T38048 |
14744-14746 |
IN |
denotes |
of |
| T48648 |
14747-14751 |
NNS |
denotes |
MERS |
| T31354 |
14752-14753 |
NN |
denotes |
S |
| T92070 |
14754-14762 |
NNS |
denotes |
proteins |
| T5507 |
14763-14767 |
WDT |
denotes |
that |
| T19099 |
14768-14776 |
VBP |
denotes |
protrude |
| T77842 |
14777-14781 |
RB |
denotes |
away |
| T99218 |
14782-14786 |
IN |
denotes |
from |
| T68020 |
14787-14790 |
DT |
denotes |
the |
| T87267 |
14791-14798 |
NNS |
denotes |
glycans |
| T55216 |
14800-14802 |
PRP |
denotes |
We |
| T15548 |
14803-14808 |
MD |
denotes |
would |
| T19328 |
14809-14816 |
VB |
denotes |
suggest |
| T73414 |
14817-14821 |
IN |
denotes |
that |
| T39503 |
14822-14826 |
DT |
denotes |
this |
| T1176 |
14827-14830 |
MD |
denotes |
may |
| T73192 |
14831-14837 |
VB |
denotes |
result |
| T18164 |
14838-14842 |
IN |
denotes |
from |
| T59646 |
14843-14846 |
DT |
denotes |
the |
| T56626 |
14847-14856 |
JJ |
denotes |
intrinsic |
| T77011 |
14857-14873 |
JJ |
denotes |
receptor-binding |
| T13068 |
14874-14887 |
NN |
denotes |
functionality |
| T25400 |
14888-14890 |
IN |
denotes |
of |
| T95940 |
14891-14896 |
DT |
denotes |
these |
| T4558 |
14897-14904 |
NNS |
denotes |
domains |
| T85225 |
14906-14914 |
IN |
denotes |
Although |
| T78299 |
14915-14920 |
NN |
denotes |
dN/dS |
| T69491 |
14921-14930 |
NNS |
denotes |
estimates |
| T17336 |
14931-14934 |
VBP |
denotes |
are |
| T68738 |
14935-14945 |
JJ |
denotes |
comparable |
| T29834 |
14946-14952 |
IN |
denotes |
within |
| T7384 |
14953-14957 |
DT |
denotes |
each |
| T38180 |
14958-14963 |
JJ |
denotes |
viral |
| T14361 |
14964-14972 |
NN |
denotes |
outbreak |
| T27804 |
14972-14973 |
-COMMA- |
denotes |
, |
| T63927 |
14974-14978 |
PRP |
denotes |
they |
| T40801 |
14979-14982 |
VBP |
denotes |
are |
| T50374 |
14983-14986 |
RB |
denotes |
not |
| T5187 |
14987-14995 |
RB |
denotes |
directly |
| T67674 |
14996-15006 |
JJ |
denotes |
comparable |
| T16791 |
15007-15014 |
IN |
denotes |
between |
| T15216 |
15015-15020 |
JJ |
denotes |
viral |
| T70745 |
15021-15029 |
NNS |
denotes |
families |
| T5519 |
15030-15032 |
IN |
denotes |
as |
| T39713 |
15033-15037 |
PRP |
denotes |
they |
| T72942 |
15038-15041 |
MD |
denotes |
can |
| T66143 |
15042-15046 |
RB |
denotes |
only |
| T83434 |
15047-15049 |
VB |
denotes |
be |
| T81231 |
15050-15060 |
VBN |
denotes |
considered |
| T66257 |
15061-15063 |
IN |
denotes |
in |
| T26996 |
15064-15067 |
DT |
denotes |
the |
| T12587 |
15068-15079 |
NN |
denotes |
environment |
| T55529 |
15080-15082 |
IN |
denotes |
in |
| T94028 |
15083-15088 |
WDT |
denotes |
which |
| T66921 |
15089-15093 |
PRP |
denotes |
they |
| T48812 |
15094-15097 |
VBP |
denotes |
are |
| T68204 |
15098-15106 |
VBN |
denotes |
measured |
| T1345 |
15107-15108 |
-LRB- |
denotes |
( |
| T50152 |
15108-15112 |
FW |
denotes |
i.e. |
| T58234 |
15113-15121 |
JJ |
denotes |
multiple |
| T20304 |
15122-15133 |
NNS |
denotes |
differences |
| T57102 |
15134-15136 |
IN |
denotes |
in |
| T44931 |
15137-15149 |
NN |
denotes |
transmission |
| T48849 |
15150-15157 |
NN |
denotes |
ecology |
| T40406 |
15158-15161 |
CC |
denotes |
and |
| T86262 |
15162-15172 |
NN |
denotes |
host-virus |
| T60225 |
15173-15185 |
NNS |
denotes |
interactions |
| T28690 |
15186-15194 |
VBP |
denotes |
disallow |
| T4001 |
15195-15205 |
JJ |
denotes |
meaningful |
| T97622 |
15206-15217 |
NNS |
denotes |
comparisons |
| T88580 |
15217-15218 |
-RRB- |
denotes |
) |
| T61778 |
15220-15223 |
IN |
denotes |
For |
| T80559 |
15224-15231 |
NN |
denotes |
example |
| T85630 |
15231-15232 |
-COMMA- |
denotes |
, |
| T13499 |
15233-15244 |
NNS |
denotes |
differences |
| T59995 |
15245-15247 |
IN |
denotes |
in |
| T19712 |
15248-15251 |
DT |
denotes |
the |
| T30994 |
15252-15260 |
JJ |
denotes |
epidemic |
| T28935 |
15261-15270 |
NN |
denotes |
behaviour |
| T90583 |
15271-15274 |
CC |
denotes |
and |
| T22228 |
15275-15279 |
NN |
denotes |
host |
| T48983 |
15280-15286 |
JJ |
denotes |
immune |
| T32345 |
15287-15298 |
NN |
denotes |
environment |
| T33520 |
15299-15301 |
IN |
denotes |
of |
| T49936 |
15302-15306 |
NNS |
denotes |
MERS |
| T62735 |
15307-15310 |
CC |
denotes |
and |
| T19591 |
15311-15315 |
NNP |
denotes |
SARS |
| T85021 |
15316-15325 |
NNS |
denotes |
outbreaks |
| T32139 |
15326-15332 |
RB |
denotes |
likely |
| T6621 |
15333-15343 |
VBP |
denotes |
contribute |
| T58427 |
15344-15346 |
TO |
denotes |
to |
| T13399 |
15347-15350 |
DT |
denotes |
the |
| T26807 |
15351-15359 |
VBN |
denotes |
observed |
| T13552 |
15360-15367 |
JJ |
denotes |
genetic |
| T43199 |
15368-15377 |
NN |
denotes |
diversity |
| T65839 |
15378-15381 |
CC |
denotes |
and |
| T79458 |
15382-15386 |
RB |
denotes |
thus |
| T98636 |
15387-15392 |
NN |
denotes |
dN/dS |
| T25443 |
15394-15398 |
NNS |
denotes |
MERS |
| T97762 |
15399-15402 |
VBD |
denotes |
was |
| T89667 |
15403-15416 |
VBN |
denotes |
characterized |
| T47196 |
15417-15419 |
IN |
denotes |
by |
| T18635 |
15420-15428 |
VBN |
denotes |
repeated |
| T30054 |
15429-15438 |
NN |
denotes |
spillover |
| T27860 |
15439-15445 |
NNS |
denotes |
events |
| T14782 |
15446-15450 |
IN |
denotes |
from |
| T25019 |
15451-15457 |
NNS |
denotes |
camels |
| T86652 |
15458-15462 |
IN |
denotes |
into |
| T1639 |
15463-15469 |
NNS |
denotes |
humans |
| T23535 |
15469-15470 |
-COMMA- |
denotes |
, |
| T51241 |
15471-15476 |
WRB |
denotes |
where |
| T67194 |
15477-15479 |
PRP |
denotes |
it |
| T59854 |
15480-15490 |
VBD |
denotes |
circulated |
| T82528 |
15491-15502 |
RB |
denotes |
transiently |
| T23126 |
15504-15506 |
IN |
denotes |
In |
| T4625 |
15507-15515 |
NN |
denotes |
contrast |
| T47309 |
15515-15516 |
-COMMA- |
denotes |
, |
| T1278 |
15517-15520 |
DT |
denotes |
the |
| T1279 |
15521-15525 |
NNP |
denotes |
SARS |
| T1280 |
15526-15534 |
NN |
denotes |
outbreak |
| T1281 |
15535-15547 |
VBD |
denotes |
corresponded |
| T1282 |
15548-15550 |
TO |
denotes |
to |
| T1283 |
15551-15552 |
DT |
denotes |
a |
| T1284 |
15553-15559 |
JJ |
denotes |
single |
| T1285 |
15560-15568 |
JJ |
denotes |
zoonotic |
| T1286 |
15569-15574 |
NN |
denotes |
event |
| T1287 |
15575-15583 |
VBN |
denotes |
followed |
| T1288 |
15584-15586 |
IN |
denotes |
by |
| T1289 |
15587-15596 |
JJ |
denotes |
extensive |
| T1290 |
15597-15611 |
JJ |
denotes |
human-to-human |
| T1291 |
15612-15624 |
NN |
denotes |
transmission |
| T1292 |
15626-15638 |
RB |
denotes |
Consequently |
| T1293 |
15638-15639 |
-COMMA- |
denotes |
, |
| T1294 |
15640-15649 |
VBG |
denotes |
inferring |
| T1295 |
15650-15653 |
DT |
denotes |
the |
| T1296 |
15654-15660 |
NN |
denotes |
degree |
| T1297 |
15661-15663 |
IN |
denotes |
of |
| T1298 |
15664-15673 |
NN |
denotes |
selection |
| T1299 |
15674-15680 |
VBG |
denotes |
acting |
| T1300 |
15681-15685 |
IN |
denotes |
upon |
| T1301 |
15686-15690 |
NNS |
denotes |
MERS |
| T1302 |
15691-15694 |
CC |
denotes |
and |
| T1303 |
15695-15699 |
NNS |
denotes |
SARS |
| T1304 |
15700-15704 |
IN |
denotes |
from |
| T1305 |
15705-15710 |
NN |
denotes |
dN/dS |
| T1306 |
15711-15719 |
NN |
denotes |
analysis |
| T1307 |
15720-15722 |
VBZ |
denotes |
is |
| T1308 |
15723-15732 |
RB |
denotes |
extremely |
| T1309 |
15733-15742 |
JJ |
denotes |
difficult |
| T1310 |
15744-15755 |
RB |
denotes |
Importantly |
| T1311 |
15755-15756 |
-COMMA- |
denotes |
, |
| T1312 |
15757-15762 |
IN |
denotes |
while |
| T1313 |
15763-15770 |
JJ |
denotes |
similar |
| T1314 |
15771-15779 |
NNS |
denotes |
analyses |
| T1315 |
15780-15782 |
IN |
denotes |
of |
| T1316 |
15783-15793 |
NN |
denotes |
SARS-CoV-2 |
| T1317 |
15794-15796 |
VBZ |
denotes |
is |
| T1318 |
15797-15806 |
JJ |
denotes |
desirable |
| T1319 |
15806-15807 |
-COMMA- |
denotes |
, |
| T1320 |
15808-15811 |
JJ |
denotes |
due |
| T1321 |
15812-15814 |
TO |
denotes |
to |
| T1322 |
15815-15818 |
DT |
denotes |
the |
| T1323 |
15819-15822 |
JJ |
denotes |
low |
| T1324 |
15823-15830 |
JJ |
denotes |
genetic |
| T1325 |
15831-15840 |
NN |
denotes |
variation |
| T1326 |
15841-15846 |
IN |
denotes |
among |
| T1327 |
15847-15850 |
DT |
denotes |
the |
| T1328 |
15851-15858 |
JJ |
denotes |
current |
| T1329 |
15859-15869 |
NN |
denotes |
SARS-CoV-2 |
| T1330 |
15870-15879 |
NNS |
denotes |
sequences |
| T1331 |
15880-15881 |
-LRB- |
denotes |
( |
| T1332 |
15881-15883 |
IN |
denotes |
as |
| T1333 |
15884-15886 |
IN |
denotes |
of |
| T1334 |
15887-15889 |
CD |
denotes |
17 |
| T1335 |
15890-15895 |
NNP |
denotes |
March |
| T1336 |
15896-15900 |
CD |
denotes |
2020 |
| T1337 |
15900-15901 |
-RRB- |
denotes |
) |
| T1338 |
15901-15902 |
-COMMA- |
denotes |
, |
| T1339 |
15903-15908 |
WDT |
denotes |
which |
| T1340 |
15909-15915 |
RB |
denotes |
likely |
| T1341 |
15916-15923 |
VBP |
denotes |
include |
| T1342 |
15924-15935 |
JJ |
denotes |
deleterious |
| T1343 |
15936-15945 |
NNS |
denotes |
mutations |
| T1344 |
15946-15950 |
WDT |
denotes |
that |
| T79570 |
15951-15955 |
MD |
denotes |
will |
| T1346 |
15956-15958 |
VB |
denotes |
be |
| T1347 |
15959-15966 |
VBN |
denotes |
removed |
| T1348 |
15967-15969 |
IN |
denotes |
by |
| T1349 |
15970-15979 |
NN |
denotes |
selection |
| T1350 |
15980-15984 |
IN |
denotes |
over |
| T1351 |
15985-15989 |
NN |
denotes |
time |
| T1352 |
15989-15990 |
-COMMA- |
denotes |
, |
| T1353 |
15991-15994 |
DT |
denotes |
the |
| T1354 |
15995-16004 |
VBG |
denotes |
resulting |
| T1355 |
16005-16018 |
JJ |
denotes |
bioinformatic |
| T1356 |
16019-16027 |
NNS |
denotes |
analyses |
| T1357 |
16028-16033 |
MD |
denotes |
would |
| T1358 |
16034-16036 |
VB |
denotes |
be |
| T1359 |
16037-16047 |
JJ |
denotes |
unreliable |
| T1360 |
16050-16061 |
VBG |
denotes |
Visualising |
| T1361 |
16062-16065 |
DT |
denotes |
the |
| T1362 |
16066-16071 |
NN |
denotes |
HIV-1 |
| T1363 |
16072-16075 |
CC |
denotes |
and |
| T1364 |
16076-16080 |
NN |
denotes |
SARS |
| T1365 |
16081-16087 |
NN |
denotes |
glycan |
| T1366 |
16088-16095 |
NNS |
denotes |
shields |
| T1367 |
16096-16098 |
IN |
denotes |
by |
| T1368 |
16099-16106 |
NN |
denotes |
cryo-EM |
| T8430 |
16107-16112 |
NN |
denotes |
HIV-1 |
| T3174 |
16113-16116 |
NN |
denotes |
Env |
| T27555 |
16117-16119 |
VBZ |
denotes |
is |
| T55541 |
16120-16121 |
DT |
denotes |
a |
| T20248 |
16122-16132 |
JJ |
denotes |
prototypic |
| T67286 |
16133-16138 |
JJ |
denotes |
viral |
| T69498 |
16139-16144 |
NN |
denotes |
class |
| T3932 |
16145-16146 |
CD |
denotes |
I |
| T49427 |
16147-16153 |
NN |
denotes |
fusion |
| T80657 |
16154-16161 |
NN |
denotes |
protein |
| T46816 |
16162-16166 |
WDT |
denotes |
that |
| T99370 |
16167-16175 |
VBZ |
denotes |
exhibits |
| T82158 |
16176-16185 |
JJ |
denotes |
extensive |
| T40184 |
16186-16193 |
NN |
denotes |
surface |
| T83381 |
16194-16207 |
NN |
denotes |
glycosylation |
| T34922 |
16207-16208 |
-COMMA- |
denotes |
, |
| T41135 |
16209-16218 |
VBG |
denotes |
resulting |
| T52094 |
16219-16221 |
IN |
denotes |
in |
| T41086 |
16222-16224 |
DT |
denotes |
an |
| T24478 |
16225-16234 |
JJ |
denotes |
effective |
| T12116 |
16235-16241 |
NN |
denotes |
glycan |
| T66049 |
16242-16248 |
NN |
denotes |
shield |
| T24089 |
16249-16251 |
TO |
denotes |
to |
| T80516 |
16252-16255 |
VB |
denotes |
aid |
| T40146 |
16256-16263 |
NN |
denotes |
evasion |
| T31245 |
16264-16268 |
IN |
denotes |
from |
| T10149 |
16269-16272 |
DT |
denotes |
the |
| T79574 |
16273-16277 |
NN |
denotes |
host |
| T93688 |
16278-16286 |
JJ |
denotes |
adaptive |
| T94198 |
16287-16293 |
JJ |
denotes |
immune |
| T10989 |
16294-16307 |
NN |
denotes |
response21,31 |
| T32196 |
16309-16311 |
IN |
denotes |
In |
| T81817 |
16312-16317 |
NN |
denotes |
order |
| T91723 |
16318-16320 |
TO |
denotes |
to |
| T52822 |
16321-16330 |
VB |
denotes |
visualize |
| T6796 |
16331-16334 |
DT |
denotes |
the |
| T38040 |
16335-16344 |
NN |
denotes |
structure |
| T51236 |
16345-16347 |
IN |
denotes |
of |
| T17574 |
16348-16351 |
DT |
denotes |
the |
| T94895 |
16352-16362 |
JJ |
denotes |
respective |
| T2313 |
16363-16369 |
NN |
denotes |
glycan |
| T39465 |
16370-16379 |
NN |
denotes |
“shields” |
| T63649 |
16380-16382 |
IN |
denotes |
of |
| T97323 |
16383-16388 |
NN |
denotes |
HIV-1 |
| T48816 |
16389-16392 |
CC |
denotes |
and |
| T59243 |
16393-16397 |
NN |
denotes |
SARS |
| T65533 |
16398-16409 |
NN |
denotes |
coronavirus |
| T26306 |
16410-16412 |
PRP |
denotes |
we |
| T89403 |
16413-16417 |
VBD |
denotes |
used |
| T31852 |
16418-16433 |
JJ |
denotes |
single-particle |
| T56676 |
16434-16447 |
NN |
denotes |
cryo-electron |
| T27050 |
16448-16458 |
NN |
denotes |
microscopy |
| T97416 |
16459-16460 |
-LRB- |
denotes |
( |
| T56321 |
16460-16467 |
NN |
denotes |
cryo-EM |
| T61586 |
16467-16468 |
-RRB- |
denotes |
) |
| T32555 |
16470-16473 |
DT |
denotes |
The |
| T47125 |
16474-16481 |
NNS |
denotes |
results |
| T36239 |
16482-16485 |
IN |
denotes |
for |
| T18889 |
16486-16491 |
NN |
denotes |
HIV-1 |
| T12931 |
16492-16495 |
NN |
denotes |
Env |
| T63067 |
16496-16500 |
VBD |
denotes |
were |
| T30265 |
16501-16511 |
VBN |
denotes |
reproduced |
| T57197 |
16512-16520 |
RB |
denotes |
directly |
| T8292 |
16521-16525 |
IN |
denotes |
from |
| T31650 |
16526-16534 |
NNP |
denotes |
Berndsen |
| T37715 |
16535-16537 |
NNP |
denotes |
et |
| T19388 |
16538-16543 |
NN |
denotes |
al.51 |
| T9777 |
16544-16549 |
IN |
denotes |
while |
| T55752 |
16550-16553 |
DT |
denotes |
the |
| T50993 |
16554-16564 |
RB |
denotes |
previously |
| T21233 |
16565-16574 |
VBN |
denotes |
published |
| T39264 |
16575-16579 |
NN |
denotes |
SARS |
| T63581 |
16580-16582 |
NN |
denotes |
2P |
| T16458 |
16583-16592 |
NN |
denotes |
dataset52 |
| T19972 |
16593-16596 |
VBD |
denotes |
was |
| T72393 |
16597-16608 |
VBN |
denotes |
reprocessed |
| T49131 |
16609-16612 |
IN |
denotes |
for |
| T60843 |
16613-16617 |
DT |
denotes |
this |
| T69625 |
16618-16623 |
NN |
denotes |
study |
| T12832 |
16625-16633 |
IN |
denotes |
Although |
| T24787 |
16634-16641 |
NN |
denotes |
cryo-EM |
| T29672 |
16642-16650 |
NNS |
denotes |
datasets |
| T9596 |
16651-16653 |
IN |
denotes |
of |
| T45576 |
16654-16659 |
RB |
denotes |
fully |
| T37894 |
16660-16672 |
VBN |
denotes |
glycosylated |
| T35124 |
16673-16677 |
NNS |
denotes |
MERS |
| T87593 |
16678-16681 |
NN |
denotes |
S41 |
| T79382 |
16682-16685 |
CC |
denotes |
and |
| T63281 |
16686-16696 |
NN |
denotes |
chimpanzee |
| T35247 |
16697-16703 |
JJ |
denotes |
simian |
| T82138 |
16704-16720 |
NN |
denotes |
immunodeficiency |
| T35287 |
16721-16726 |
NN |
denotes |
virus |
| T14224 |
16727-16728 |
-LRB- |
denotes |
( |
| T81517 |
16728-16734 |
NN |
denotes |
SIVcpz |
| T3442 |
16734-16735 |
-RRB- |
denotes |
) |
| T14676 |
16735-16737 |
CD |
denotes |
53 |
| T32530 |
16738-16741 |
VBP |
denotes |
are |
| T45598 |
16742-16746 |
RB |
denotes |
also |
| T95444 |
16747-16756 |
JJ |
denotes |
available |
| T17171 |
16756-16757 |
-COMMA- |
denotes |
, |
| T88916 |
16758-16762 |
RB |
denotes |
only |
| T2700 |
16763-16766 |
DT |
denotes |
the |
| T19064 |
16767-16770 |
NN |
denotes |
HIV |
| T16401 |
16771-16774 |
CC |
denotes |
and |
| T74879 |
16775-16779 |
NN |
denotes |
SARS |
| T37597 |
16780-16784 |
NNS |
denotes |
data |
| T46398 |
16785-16789 |
VBD |
denotes |
were |
| T10901 |
16790-16792 |
IN |
denotes |
of |
| T19935 |
16793-16803 |
JJ |
denotes |
sufficient |
| T58744 |
16804-16811 |
NN |
denotes |
quality |
| T47642 |
16812-16813 |
-LRB- |
denotes |
( |
| T27616 |
16813-16819 |
CD |
denotes |
Fig. 5 |
| T15042 |
16819-16820 |
-RRB- |
denotes |
) |
| T64790 |
16822-16824 |
PRP |
denotes |
We |
| T12200 |
16825-16833 |
RB |
denotes |
recently |
| T55283 |
16834-16842 |
VBD |
denotes |
showed51 |
| T5337 |
16843-16847 |
IN |
denotes |
that |
| T85969 |
16848-16856 |
NNS |
denotes |
dynamics |
| T15501 |
16857-16859 |
IN |
denotes |
in |
| T81842 |
16860-16867 |
NN |
denotes |
surface |
| T53947 |
16868-16875 |
VBN |
denotes |
exposed |
| T58293 |
16876-16883 |
NNS |
denotes |
glycans |
| T78469 |
16884-16889 |
NN |
denotes |
HIV-1 |
| T11314 |
16890-16893 |
NN |
denotes |
Env |
| T63261 |
16894-16899 |
VBZ |
denotes |
leads |
| T50401 |
16900-16902 |
TO |
denotes |
to |
| T72222 |
16903-16905 |
DT |
denotes |
an |
| T69150 |
16906-16915 |
JJ |
denotes |
extensive |
| T26975 |
16916-16923 |
NN |
denotes |
network |
| T64977 |
16924-16926 |
IN |
denotes |
of |
| T71776 |
16927-16939 |
NNS |
denotes |
interactions |
| T7784 |
16940-16944 |
WDT |
denotes |
that |
| T35226 |
16945-16950 |
VBP |
denotes |
drive |
| T68570 |
16951-16963 |
JJR |
denotes |
higher-order |
| T34602 |
16964-16975 |
NN |
denotes |
structuring |
| T35212 |
16976-16978 |
IN |
denotes |
in |
| T61552 |
16979-16982 |
DT |
denotes |
the |
| T88226 |
16983-16989 |
NN |
denotes |
glycan |
| T2686 |
16990-16996 |
NN |
denotes |
shield |
| T70456 |
16998-17002 |
DT |
denotes |
This |
| T49009 |
17003-17012 |
NN |
denotes |
structure |
| T80667 |
17013-17020 |
VBZ |
denotes |
defines |
| T33829 |
17021-17028 |
JJ |
denotes |
diffuse |
| T1508 |
17029-17039 |
NNS |
denotes |
boundaries |
| T66208 |
17040-17047 |
IN |
denotes |
between |
| T95551 |
17048-17054 |
VBN |
denotes |
buried |
| T27513 |
17055-17058 |
CC |
denotes |
and |
| T63689 |
17059-17066 |
VBN |
denotes |
exposed |
| T23712 |
17067-17074 |
NN |
denotes |
surface |
| T90175 |
17075-17082 |
NN |
denotes |
protein |
| T66804 |
17083-17090 |
NN |
denotes |
surface |
| T71072 |
17090-17091 |
-COMMA- |
denotes |
, |
| T80348 |
17092-17097 |
WDT |
denotes |
which |
| T9316 |
17098-17101 |
MD |
denotes |
can |
| T90504 |
17102-17107 |
VB |
denotes |
serve |
| T42110 |
17108-17110 |
TO |
denotes |
to |
| T69932 |
17111-17117 |
VB |
denotes |
define |
| T67682 |
17118-17127 |
JJ |
denotes |
potential |
| T2204 |
17128-17133 |
NNS |
denotes |
sites |
| T70578 |
17134-17136 |
IN |
denotes |
of |
| T95274 |
17137-17150 |
NN |
denotes |
vulnerability |
| T46703 |
17152-17159 |
NN |
denotes |
Cryo-EM |
| T30395 |
17160-17168 |
VBZ |
denotes |
captures |
| T87072 |
17169-17172 |
DT |
denotes |
the |
| T44958 |
17173-17189 |
JJ |
denotes |
ensemble-average |
| T7879 |
17190-17199 |
NN |
denotes |
structure |
| T75651 |
17200-17202 |
IN |
denotes |
of |
| T66273 |
17203-17215 |
NNS |
denotes |
biomolecules |
| T73691 |
17216-17219 |
CC |
denotes |
and |
| T31109 |
17220-17229 |
RB |
denotes |
therefore |
| T12255 |
17230-17236 |
NN |
denotes |
glycan |
| T11220 |
17237-17245 |
NNS |
denotes |
dynamics |
| T43250 |
17246-17253 |
VBZ |
denotes |
results |
| T52169 |
17254-17256 |
IN |
denotes |
in |
| T64021 |
17257-17264 |
VBN |
denotes |
blurred |
| T49153 |
17265-17272 |
NN |
denotes |
density |
| T2441 |
17273-17275 |
IN |
denotes |
at |
| T80700 |
17276-17279 |
DT |
denotes |
the |
| T16085 |
17280-17291 |
NNS |
denotes |
resolutions |
| T86172 |
17292-17301 |
JJ |
denotes |
necessary |
| T28589 |
17302-17305 |
IN |
denotes |
for |
| T42839 |
17306-17314 |
VBG |
denotes |
building |
| T3599 |
17315-17321 |
JJ |
denotes |
atomic |
| T43748 |
17322-17331 |
NN |
denotes |
structure |
| T10071 |
17333-17340 |
RB |
denotes |
However |
| T88433 |
17340-17341 |
-COMMA- |
denotes |
, |
| T97506 |
17342-17344 |
PRP |
denotes |
we |
| T94206 |
17345-17351 |
VBD |
denotes |
showed |
| T91691 |
17352-17355 |
WRB |
denotes |
how |
| T17411 |
17356-17357 |
DT |
denotes |
a |
| T2527 |
17358-17364 |
JJ |
denotes |
simple |
| T82430 |
17365-17376 |
NN |
denotes |
combination |
| T32469 |
17377-17379 |
IN |
denotes |
of |
| T40028 |
17380-17388 |
JJ |
denotes |
low-pass |
| T93291 |
17389-17398 |
NN |
denotes |
filtering |
| T10413 |
17399-17402 |
CC |
denotes |
and |
| T2487 |
17403-17420 |
NN |
denotes |
auto-thresholding |
| T78379 |
17420-17421 |
-COMMA- |
denotes |
, |
| T27010 |
17422-17424 |
RB |
denotes |
as |
| T32044 |
17425-17429 |
RB |
denotes |
well |
| T89162 |
17430-17432 |
IN |
denotes |
as |
| T8187 |
17433-17435 |
NN |
denotes |
3D |
| T99213 |
17436-17447 |
NN |
denotes |
variability |
| T14190 |
17448-17456 |
NN |
denotes |
analysis |
| T81037 |
17456-17457 |
-COMMA- |
denotes |
, |
| T87732 |
17458-17461 |
MD |
denotes |
can |
| T9264 |
17462-17468 |
VB |
denotes |
reveal |
| T36472 |
17469-17472 |
DT |
denotes |
the |
| T15866 |
17473-17483 |
RB |
denotes |
previously |
| T33845 |
17484-17490 |
VBN |
denotes |
hidden |
| T31709 |
17491-17500 |
NN |
denotes |
structure |
| T97881 |
17501-17503 |
IN |
denotes |
of |
| T77189 |
17504-17507 |
DT |
denotes |
the |
| T22984 |
17508-17512 |
NNP |
denotes |
SARS |
| T32877 |
17513-17519 |
NN |
denotes |
glycan |
| T15037 |
17520-17526 |
NN |
denotes |
shield |
| T70541 |
17527-17530 |
CC |
denotes |
and |
| T30415 |
17531-17538 |
VB |
denotes |
compare |
| T37461 |
17539-17541 |
PRP |
denotes |
it |
| T52236 |
17542-17546 |
IN |
denotes |
with |
| T25513 |
17547-17550 |
DT |
denotes |
the |
| T63380 |
17551-17556 |
NN |
denotes |
HIV-1 |
| T80636 |
17557-17560 |
NN |
denotes |
Env |
| T69159 |
17561-17567 |
NN |
denotes |
glycan |
| T3337 |
17568-17576 |
NN |
denotes |
shield51 |
| T64033 |
17577-17578 |
-LRB- |
denotes |
( |
| T94502 |
17578-17584 |
CD |
denotes |
Fig. 5 |
| T94581 |
17584-17585 |
-RRB- |
denotes |
) |
| T60289 |
17587-17589 |
PRP |
denotes |
We |
| T75223 |
17590-17597 |
VBP |
denotes |
observe |
| T57545 |
17598-17601 |
DT |
denotes |
the |
| T48330 |
17602-17608 |
RB |
denotes |
nearly |
| T87308 |
17609-17625 |
JJ |
denotes |
all-encompassing |
| T1558 |
17626-17632 |
NN |
denotes |
glycan |
| T99824 |
17633-17640 |
NN |
denotes |
density |
| T59798 |
17641-17643 |
IN |
denotes |
on |
| T56235 |
17644-17649 |
NN |
denotes |
HIV-1 |
| T14383 |
17650-17653 |
NN |
denotes |
Env |
| T33263 |
17654-17657 |
CC |
denotes |
and |
| T4213 |
17658-17666 |
NN |
denotes |
evidence |
| T91161 |
17667-17670 |
IN |
denotes |
for |
| T79082 |
17671-17680 |
JJ |
denotes |
extensive |
| T66189 |
17681-17694 |
NN |
denotes |
glycan–glycan |
| T48593 |
17695-17707 |
NNS |
denotes |
interactions |
| T42535 |
17707-17708 |
-COMMA- |
denotes |
, |
| T14663 |
17709-17719 |
RB |
denotes |
especially |
| T44869 |
17720-17722 |
IN |
denotes |
in |
| T77065 |
17723-17726 |
DT |
denotes |
the |
| T90752 |
17727-17739 |
NN |
denotes |
oligomannose |
| T24864 |
17740-17745 |
NN |
denotes |
patch |
| T20998 |
17746-17753 |
NNS |
denotes |
regions |
| T55492 |
17753-17754 |
-COMMA- |
denotes |
, |
| T69929 |
17755-17762 |
IN |
denotes |
whereas |
| T90575 |
17763-17766 |
DT |
denotes |
the |
| T59031 |
17767-17774 |
NNS |
denotes |
glycans |
| T94235 |
17775-17777 |
IN |
denotes |
on |
| T22232 |
17778-17782 |
NNP |
denotes |
SARS |
| T7541 |
17783-17784 |
NNP |
denotes |
S |
| T66013 |
17785-17791 |
VBP |
denotes |
appear |
| T27090 |
17792-17796 |
RBR |
denotes |
more |
| T7370 |
17797-17805 |
VBN |
denotes |
isolated |
| T67487 |
17806-17809 |
CC |
denotes |
and |
| T50530 |
17810-17814 |
VBP |
denotes |
lack |
| T21892 |
17815-17818 |
DT |
denotes |
the |
| T55852 |
17819-17831 |
JJ |
denotes |
wide-ranging |
| T70160 |
17832-17838 |
NN |
denotes |
glycan |
| T80844 |
17839-17847 |
NNS |
denotes |
networks |
| T83936 |
17848-17852 |
WDT |
denotes |
that |
| T81018 |
17853-17856 |
VBP |
denotes |
are |
| T68036 |
17857-17860 |
DT |
denotes |
the |
| T82951 |
17861-17869 |
NN |
denotes |
hallmark |
| T16903 |
17870-17872 |
IN |
denotes |
of |
| T2902 |
17873-17875 |
DT |
denotes |
an |
| T18742 |
17876-17885 |
JJ |
denotes |
effective |
| T88640 |
17886-17892 |
NN |
denotes |
glycan |
| T57983 |
17893-17904 |
NN |
denotes |
shield54,55 |
| T96638 |
17906-17909 |
DT |
denotes |
The |
| T9355 |
17910-17912 |
NN |
denotes |
3D |
| T47791 |
17913-17924 |
NN |
denotes |
variability |
| T79677 |
17925-17929 |
NNS |
denotes |
maps |
| T51290 |
17930-17933 |
VBP |
denotes |
are |
| T66740 |
17934-17938 |
RBR |
denotes |
more |
| T28675 |
17939-17948 |
JJ |
denotes |
sensitive |
| T51626 |
17949-17951 |
TO |
denotes |
to |
| T96563 |
17952-17955 |
JJ |
denotes |
low |
| T5756 |
17956-17965 |
NN |
denotes |
intensity |
| T42122 |
17966-17972 |
NN |
denotes |
signal |
| T93380 |
17973-17976 |
CC |
denotes |
and |
| T52275 |
17977-17983 |
VBP |
denotes |
reveal |
| T65761 |
17984-17994 |
JJ |
denotes |
additional |
| T40659 |
17995-18008 |
NN |
denotes |
glycan–glycan |
| T18648 |
18009-18021 |
NNS |
denotes |
interactions |
| T53697 |
18022-18024 |
IN |
denotes |
in |
| T13379 |
18025-18029 |
DT |
denotes |
both |
| T61777 |
18030-18034 |
NNS |
denotes |
maps |
| T1991 |
18034-18035 |
-COMMA- |
denotes |
, |
| T10706 |
18036-18043 |
RB |
denotes |
however |
| T21547 |
18044-18047 |
DT |
denotes |
the |
| T89902 |
18048-18050 |
NN |
denotes |
S1 |
| T24397 |
18051-18067 |
JJ |
denotes |
receptor-binding |
| T67026 |
18068-18075 |
NNS |
denotes |
domains |
| T98351 |
18076-18078 |
IN |
denotes |
in |
| T69700 |
18079-18082 |
DT |
denotes |
the |
| T97210 |
18083-18087 |
NN |
denotes |
SARS |
| T19203 |
18088-18095 |
NN |
denotes |
dataset |
| T21495 |
18096-18100 |
VBD |
denotes |
were |
| T3893 |
18101-18106 |
VBN |
denotes |
shown |
| T33461 |
18107-18109 |
TO |
denotes |
to |
| T68704 |
18110-18115 |
VB |
denotes |
exist |
| T1970 |
18116-18118 |
IN |
denotes |
in |
| T91066 |
18119-18123 |
CC |
denotes |
both |
| T75781 |
18124-18126 |
RB |
denotes |
up |
| T44006 |
18127-18130 |
CC |
denotes |
and |
| T47879 |
18131-18135 |
IN |
denotes |
down |
| T22009 |
18136-18151 |
NN |
denotes |
conformations52 |
| T80149 |
18151-18152 |
-COMMA- |
denotes |
, |
| T10724 |
18153-18160 |
VBG |
denotes |
leading |
| T29355 |
18161-18163 |
TO |
denotes |
to |
| T48291 |
18164-18168 |
JJ |
denotes |
poor |
| T15651 |
18169-18179 |
NN |
denotes |
resolution |
| T15044 |
18180-18183 |
CC |
denotes |
and |
| T36313 |
18184-18195 |
JJ |
denotes |
significant |
| T78120 |
18196-18210 |
NN |
denotes |
2D-variability |
| T97054 |
18211-18216 |
WDT |
denotes |
which |
| T80897 |
18217-18219 |
VBZ |
denotes |
is |
| T73857 |
18220-18229 |
VBN |
denotes |
convolved |
| T52453 |
18230-18234 |
IN |
denotes |
with |
| T12417 |
18235-18238 |
DT |
denotes |
the |
| T9415 |
18239-18250 |
NN |
denotes |
variability |
| T91463 |
18251-18257 |
VBG |
denotes |
coming |
| T37758 |
18258-18262 |
IN |
denotes |
from |
| T69399 |
18263-18270 |
NNS |
denotes |
glycans |
| T37469 |
18271-18274 |
CC |
denotes |
and |
| T7534 |
18275-18281 |
VBZ |
denotes |
limits |
| T29335 |
18282-18285 |
DT |
denotes |
the |
| T16169 |
18286-18302 |
NN |
denotes |
interpretability |
| T54909 |
18303-18305 |
IN |
denotes |
of |
| T36751 |
18306-18312 |
NN |
denotes |
glycan |
| T68517 |
18313-18322 |
NN |
denotes |
shielding |
| T73688 |
18323-18330 |
NNS |
denotes |
effects |
| T27520 |
18331-18333 |
IN |
denotes |
in |
| T1634 |
18334-18338 |
DT |
denotes |
this |
| T15004 |
18339-18345 |
NN |
denotes |
region |
| T14842 |
18346-18348 |
IN |
denotes |
of |
| T18381 |
18349-18352 |
DT |
denotes |
the |
| T85741 |
18353-18356 |
NN |
denotes |
map |
| T77710 |
18358-18362 |
NNP |
denotes |
Fig. |
| T43639 |
18363-18364 |
CD |
denotes |
5 |
| T80136 |
18365-18376 |
JJ |
denotes |
Comparative |
| T57723 |
18377-18384 |
NN |
denotes |
cryo-EM |
| T19047 |
18385-18393 |
NN |
denotes |
analysis |
| T52944 |
18394-18396 |
IN |
denotes |
of |
| T86979 |
18397-18401 |
NNP |
denotes |
SARS |
| T71022 |
18402-18403 |
NNP |
denotes |
S |
| T87387 |
18404-18407 |
CC |
denotes |
and |
| T92374 |
18408-18413 |
NN |
denotes |
HIV-1 |
| T58960 |
18414-18417 |
NN |
denotes |
Env |
| T67673 |
18418-18424 |
NN |
denotes |
glycan |
| T21302 |
18425-18432 |
NNS |
denotes |
shields |
| T48820 |
18434-18435 |
DT |
denotes |
a |
| T79466 |
18436-18440 |
NNP |
denotes |
Left |
| T16113 |
18441-18446 |
NN |
denotes |
panel |
| T98169 |
18446-18447 |
-COLON- |
denotes |
: |
| T63629 |
18448-18457 |
VBN |
denotes |
Sharpened |
| T90429 |
18458-18474 |
JJ |
denotes |
3.2-Å-resolution |
| T6423 |
18475-18487 |
JJ |
denotes |
C3-symmetric |
| T13124 |
18488-18495 |
NN |
denotes |
cryo-EM |
| T56273 |
18496-18499 |
NN |
denotes |
map |
| T86558 |
18500-18502 |
IN |
denotes |
of |
| T37174 |
18503-18507 |
NNP |
denotes |
SARS |
| T84496 |
18508-18509 |
NNP |
denotes |
S |
| T86959 |
18510-18512 |
NN |
denotes |
2P |
| T75209 |
18513-18525 |
NN |
denotes |
ectodomain52 |
| T37067 |
18526-18536 |
VBN |
denotes |
visualized |
| T22530 |
18537-18539 |
IN |
denotes |
at |
| T60171 |
18540-18541 |
DT |
denotes |
a |
| T27128 |
18542-18546 |
JJ |
denotes |
high |
| T94740 |
18547-18554 |
NN |
denotes |
contour |
| T58510 |
18555-18560 |
NN |
denotes |
level |
| T66412 |
18561-18565 |
IN |
denotes |
with |
| T32176 |
18566-18576 |
VBN |
denotes |
disordered |
| T5395 |
18577-18579 |
NN |
denotes |
S1 |
| T34000 |
18580-18596 |
JJ |
denotes |
receptor-binding |
| T54890 |
18597-18600 |
CC |
denotes |
and |
| T9018 |
18601-18611 |
JJ |
denotes |
N-terminal |
| T68442 |
18612-18619 |
NNS |
denotes |
domains |
| T72184 |
18620-18629 |
VBG |
denotes |
extending |
| T12801 |
18630-18633 |
RP |
denotes |
out |
| T26493 |
18634-18638 |
IN |
denotes |
from |
| T4854 |
18639-18642 |
DT |
denotes |
the |
| T35333 |
18643-18650 |
JJ |
denotes |
central |
| T39891 |
18651-18655 |
NN |
denotes |
core |
| T4786 |
18657-18663 |
JJ |
denotes |
Middle |
| T40721 |
18664-18669 |
NN |
denotes |
panel |
| T2753 |
18669-18670 |
-COLON- |
denotes |
: |
| T68941 |
18671-18679 |
JJ |
denotes |
Low-pass |
| T98545 |
18680-18688 |
VBN |
denotes |
filtered |
| T5712 |
18689-18690 |
-LRB- |
denotes |
( |
| T65635 |
18690-18693 |
NN |
denotes |
lpf |
| T36825 |
18693-18694 |
-RRB- |
denotes |
) |
| T66628 |
18695-18702 |
NN |
denotes |
cryo-EM |
| T90188 |
18703-18706 |
NN |
denotes |
map |
| T57750 |
18707-18709 |
IN |
denotes |
of |
| T25808 |
18710-18713 |
DT |
denotes |
the |
| T69826 |
18714-18726 |
NN |
denotes |
glycoprotein |
| T87240 |
18727-18737 |
VBN |
denotes |
visualised |
| T62278 |
18738-18740 |
IN |
denotes |
at |
| T88612 |
18741-18742 |
DT |
denotes |
a |
| T55069 |
18743-18746 |
JJ |
denotes |
low |
| T38898 |
18747-18754 |
NN |
denotes |
contour |
| T68027 |
18755-18760 |
NN |
denotes |
level |
| T69920 |
18761-18766 |
IN |
denotes |
along |
| T22579 |
18767-18771 |
IN |
denotes |
with |
| T51416 |
18772-18773 |
DT |
denotes |
a |
| T26917 |
18774-18783 |
JJ |
denotes |
simulated |
| T72481 |
18784-18796 |
JJ |
denotes |
peptide-only |
| T91266 |
18797-18800 |
NN |
denotes |
map |
| T43073 |
18801-18809 |
NN |
denotes |
overlaid |
| T20774 |
18811-18816 |
JJ |
denotes |
Right |
| T74921 |
18817-18822 |
NN |
denotes |
panel |
| T5294 |
18822-18823 |
-COLON- |
denotes |
: |
| T27512 |
18824-18829 |
NN |
denotes |
SPARX |
| T17578 |
18830-18832 |
NN |
denotes |
3D |
| T69974 |
18833-18844 |
NN |
denotes |
variability |
| T86316 |
18845-18851 |
NN |
denotes |
map51. |
| T39562 |
18852-18853 |
NN |
denotes |
b |
| T43304 |
18854-18858 |
JJ |
denotes |
Same |
| T52255 |
18859-18861 |
IN |
denotes |
as |
| T48004 |
18862-18864 |
IN |
denotes |
in |
| T51718 |
18865-18866 |
-LRB- |
denotes |
( |
| T36617 |
18866-18867 |
DT |
denotes |
a |
| T97382 |
18867-18868 |
-RRB- |
denotes |
) |
| T54597 |
18869-18872 |
CC |
denotes |
but |
| T81241 |
18873-18876 |
IN |
denotes |
for |
| T90782 |
18877-18882 |
NN |
denotes |
HIV-1 |
| T13950 |
18883-18886 |
NNP |
denotes |
Env |
| T55209 |
18887-18892 |
NN |
denotes |
BG505 |
| T53941 |
18893-18902 |
NN |
denotes |
SOSIP.664 |
| T83312 |
18903-18912 |
NN |
denotes |
construct |
| T96415 |
18913-18915 |
IN |
denotes |
in |
| T45843 |
18916-18923 |
NN |
denotes |
complex |
| T56194 |
18924-18928 |
IN |
denotes |
with |
| T46276 |
18929-18934 |
CD |
denotes |
three |
| T95298 |
18935-18941 |
NNS |
denotes |
copies |
| T19490 |
18942-18944 |
IN |
denotes |
of |
| T71992 |
18945-18951 |
NN |
denotes |
RM20A3 |
| T28802 |
18952-18965 |
JJ |
denotes |
base-specific |
| T65942 |
18966-18972 |
NN |
denotes |
Fabs51 |
| T27171 |
18975-18984 |
JJ |
denotes |
Disparate |
| T82701 |
18985-18994 |
NN |
denotes |
shielding |
| T84269 |
18995-19005 |
NNS |
denotes |
efficacies |
| T39330 |
19006-19008 |
IN |
denotes |
of |
| T82468 |
19009-19014 |
JJ |
denotes |
viral |
| T81349 |
19015-19028 |
NN |
denotes |
glycosylation |
| T55443 |
19029-19034 |
JJ |
denotes |
Viral |
| T49065 |
19035-19043 |
NN |
denotes |
envelope |
| T84653 |
19044-19052 |
NNS |
denotes |
proteins |
| T43155 |
19053-19056 |
VBP |
denotes |
are |
| T38543 |
19057-19069 |
VBN |
denotes |
glycosylated |
| T78070 |
19070-19072 |
TO |
denotes |
to |
| T10289 |
19073-19080 |
VBG |
denotes |
varying |
| T40134 |
19081-19088 |
NNS |
denotes |
degrees |
| T67415 |
19088-19089 |
-COMMA- |
denotes |
, |
| T91973 |
19090-19093 |
CC |
denotes |
but |
| T56277 |
19094-19103 |
VBG |
denotes |
depending |
| T67259 |
19104-19106 |
IN |
denotes |
on |
| T24257 |
19107-19112 |
PRP-DOLLAR- |
denotes |
their |
| T41537 |
19113-19120 |
JJ |
denotes |
overall |
| T90997 |
19121-19125 |
NN |
denotes |
mass |
| T80023 |
19125-19126 |
-COMMA- |
denotes |
, |
| T58957 |
19127-19134 |
NN |
denotes |
surface |
| T24905 |
19135-19139 |
NN |
denotes |
area |
| T39391 |
19139-19140 |
-COMMA- |
denotes |
, |
| T28342 |
19141-19144 |
CC |
denotes |
and |
| T95089 |
19145-19151 |
NN |
denotes |
volume |
| T63529 |
19151-19152 |
-COMMA- |
denotes |
, |
| T2361 |
19153-19156 |
DT |
denotes |
the |
| T67520 |
19157-19164 |
JJ |
denotes |
overall |
| T74143 |
19165-19172 |
NN |
denotes |
density |
| T41564 |
19173-19175 |
IN |
denotes |
of |
| T83144 |
19176-19182 |
NN |
denotes |
glycan |
| T18180 |
19183-19192 |
NN |
denotes |
shielding |
| T4164 |
19193-19196 |
MD |
denotes |
may |
| T65417 |
19197-19203 |
VB |
denotes |
differ |
| T71938 |
19204-19217 |
RB |
denotes |
significantly |
| T57335 |
19219-19222 |
IN |
denotes |
For |
| T68440 |
19223-19230 |
NN |
denotes |
example |
| T98634 |
19230-19231 |
-COMMA- |
denotes |
, |
| T80942 |
19232-19236 |
CC |
denotes |
both |
| T39961 |
19237-19241 |
NN |
denotes |
LASV |
| T61867 |
19242-19245 |
NN |
denotes |
GPC |
| T97427 |
19246-19249 |
CC |
denotes |
and |
| T69629 |
19250-19261 |
NN |
denotes |
coronavirus |
| T13147 |
19262-19263 |
NN |
denotes |
S |
| T76361 |
19264-19272 |
NNS |
denotes |
proteins |
| T11359 |
19273-19280 |
VBP |
denotes |
consist |
| T63374 |
19281-19283 |
IN |
denotes |
of |
| T22368 |
19284-19286 |
CD |
denotes |
25 |
| T83476 |
19286-19287 |
NN |
denotes |
% |
| T86335 |
19288-19294 |
NN |
denotes |
glycan |
| T7181 |
19295-19297 |
IN |
denotes |
by |
| T64282 |
19298-19307 |
JJ |
denotes |
molecular |
| T19690 |
19308-19314 |
NN |
denotes |
weight |
| T82304 |
19316-19323 |
RB |
denotes |
However |
| T18710 |
19323-19324 |
-COMMA- |
denotes |
, |
| T92980 |
19325-19330 |
VBN |
denotes |
given |
| T59451 |
19331-19334 |
DT |
denotes |
the |
| T14852 |
19335-19348 |
RB |
denotes |
significantly |
| T91376 |
19349-19355 |
JJR |
denotes |
larger |
| T30498 |
19356-19363 |
NN |
denotes |
protein |
| T87161 |
19364-19371 |
NN |
denotes |
surface |
| T40590 |
19372-19376 |
NN |
denotes |
area |
| T34685 |
19377-19380 |
CC |
denotes |
and |
| T68729 |
19381-19387 |
NN |
denotes |
volume |
| T30100 |
19388-19390 |
IN |
denotes |
of |
| T69433 |
19391-19402 |
NN |
denotes |
coronavirus |
| T57189 |
19403-19404 |
NN |
denotes |
S |
| T90347 |
19405-19413 |
NNS |
denotes |
proteins |
| T54950 |
19413-19414 |
-COMMA- |
denotes |
, |
| T25542 |
19415-19423 |
NN |
denotes |
coverage |
| T55713 |
19424-19426 |
IN |
denotes |
of |
| T73077 |
19427-19430 |
DT |
denotes |
the |
| T91248 |
19431-19437 |
NN |
denotes |
glycan |
| T75525 |
19438-19446 |
NN |
denotes |
“shield” |
| T85581 |
19447-19451 |
IN |
denotes |
over |
| T10462 |
19452-19455 |
DT |
denotes |
the |
| T38271 |
19456-19469 |
JJ |
denotes |
proteinaceous |
| T15422 |
19470-19477 |
NN |
denotes |
surface |
| T79412 |
19478-19480 |
VBZ |
denotes |
is |
| T84846 |
19481-19493 |
RB |
denotes |
considerably |
| T29000 |
19494-19501 |
JJR |
denotes |
sparser |
| T67524 |
19502-19504 |
IN |
denotes |
in |
| T19223 |
19505-19515 |
NN |
denotes |
comparison |
| T56739 |
19516-19518 |
TO |
denotes |
to |
| T26633 |
19519-19522 |
DT |
denotes |
the |
| T50837 |
19523-19530 |
JJR |
denotes |
smaller |
| T14862 |
19531-19535 |
NN |
denotes |
LASV |
| T24662 |
19536-19539 |
NN |
denotes |
GPC |
| T66930 |
19539-19540 |
-COMMA- |
denotes |
, |
| T41800 |
19541-19546 |
WDT |
denotes |
which |
| T43310 |
19547-19555 |
VBZ |
denotes |
occludes |
| T12542 |
19556-19557 |
DT |
denotes |
a |
| T78671 |
19558-19561 |
RB |
denotes |
far |
| T97136 |
19562-19569 |
JJR |
denotes |
greater |
| T85689 |
19570-19580 |
NN |
denotes |
proportion |
| T37643 |
19581-19583 |
IN |
denotes |
of |
| T83557 |
19584-19587 |
DT |
denotes |
the |
| T32584 |
19588-19595 |
NN |
denotes |
protein |
| T81297 |
19596-19603 |
NN |
denotes |
surface |
| T57424 |
19604-19608 |
IN |
denotes |
with |
| T34206 |
19609-19614 |
JJR |
denotes |
fewer |
| T37921 |
19615-19622 |
NNS |
denotes |
glycans |
| T28846 |
19624-19626 |
TO |
denotes |
To |
| T62794 |
19627-19638 |
VB |
denotes |
demonstrate |
| T60590 |
19639-19643 |
IN |
denotes |
that |
| T13036 |
19644-19647 |
DT |
denotes |
the |
| T83020 |
19648-19656 |
NN |
denotes |
presence |
| T39523 |
19657-19659 |
IN |
denotes |
of |
| T3739 |
19660-19673 |
NN |
denotes |
glycosylation |
| T70902 |
19674-19679 |
VBZ |
denotes |
plays |
| T36916 |
19680-19681 |
DT |
denotes |
a |
| T54253 |
19682-19687 |
JJ |
denotes |
major |
| T97319 |
19688-19692 |
NN |
denotes |
role |
| T80278 |
19693-19695 |
IN |
denotes |
in |
| T56668 |
19696-19699 |
DT |
denotes |
the |
| T5602 |
19700-19706 |
JJ |
denotes |
immune |
| T20048 |
19707-19715 |
NN |
denotes |
response |
| T51090 |
19716-19718 |
TO |
denotes |
to |
| T73801 |
19719-19724 |
DT |
denotes |
these |
| T88581 |
19725-19734 |
JJ |
denotes |
different |
| T72197 |
19735-19748 |
NNS |
denotes |
glycoproteins |
| T95182 |
19748-19749 |
-COMMA- |
denotes |
, |
| T91428 |
19750-19752 |
PRP |
denotes |
we |
| T10009 |
19753-19760 |
VBD |
denotes |
studied |
| T37828 |
19761-19764 |
DT |
denotes |
the |
| T67976 |
19765-19772 |
NN |
denotes |
glycome |
| T12260 |
19773-19775 |
IN |
denotes |
of |
| T57382 |
19776-19783 |
JJ |
denotes |
several |
| T97617 |
19784-19796 |
RB |
denotes |
biomedically |
| T89645 |
19797-19806 |
JJ |
denotes |
important |
| T8512 |
19807-19820 |
NNS |
denotes |
coronaviruses |
| T62759 |
19821-19824 |
CC |
denotes |
and |
| T88912 |
19825-19833 |
VBN |
denotes |
compared |
| T64812 |
19834-19839 |
PRP-DOLLAR- |
denotes |
their |
| T90729 |
19840-19846 |
NN |
denotes |
glycan |
| T6629 |
19847-19859 |
NNS |
denotes |
compositions |
| T15821 |
19860-19862 |
IN |
denotes |
in |
| T75735 |
19863-19864 |
DT |
denotes |
a |
| T68214 |
19865-19875 |
JJ |
denotes |
structural |
| T93322 |
19876-19883 |
NN |
denotes |
context |
| T77334 |
19885-19887 |
PRP |
denotes |
We |
| T62822 |
19888-19892 |
RB |
denotes |
then |
| T3264 |
19893-19905 |
VBD |
denotes |
investigated |
| T90908 |
19906-19909 |
DT |
denotes |
the |
| T93386 |
19910-19916 |
NN |
denotes |
glycan |
| T20732 |
19917-19923 |
NN |
denotes |
shield |
| T38777 |
19924-19933 |
NNS |
denotes |
densities |
| T13008 |
19934-19936 |
IN |
denotes |
of |
| T66872 |
19937-19942 |
CD |
denotes |
seven |
| T69255 |
19943-19948 |
JJ |
denotes |
viral |
| T47768 |
19949-19954 |
NN |
denotes |
class |
| T56776 |
19955-19956 |
CD |
denotes |
I |
| T4483 |
19957-19963 |
NN |
denotes |
fusion |
| T51449 |
19964-19972 |
NNS |
denotes |
proteins |
| T68472 |
19973-19978 |
VBG |
denotes |
using |
| T54019 |
19979-19980 |
DT |
denotes |
a |
| T34571 |
19981-19987 |
JJ |
denotes |
global |
| T29179 |
19988-19998 |
JJ |
denotes |
structural |
| T72666 |
19999-20007 |
NN |
denotes |
approach |
| T29830 |
20008-20013 |
WDT |
denotes |
which |
| T75361 |
20014-20017 |
VBD |
denotes |
was |
| T60433 |
20018-20028 |
VBN |
denotes |
calculated |
| T21150 |
20029-20031 |
IN |
denotes |
by |
| T65408 |
20032-20040 |
VBG |
denotes |
dividing |
| T12510 |
20041-20044 |
DT |
denotes |
the |
| T47420 |
20045-20051 |
NN |
denotes |
number |
| T7804 |
20052-20054 |
IN |
denotes |
of |
| T96477 |
20055-20066 |
NNS |
denotes |
amino-acids |
| T57287 |
20067-20071 |
WDT |
denotes |
that |
| T31963 |
20072-20080 |
VBP |
denotes |
interact |
| T11453 |
20081-20085 |
IN |
denotes |
with |
| T5466 |
20086-20093 |
NNS |
denotes |
glycans |
| T67617 |
20094-20096 |
IN |
denotes |
by |
| T76751 |
20097-20100 |
DT |
denotes |
the |
| T95787 |
20101-20107 |
NN |
denotes |
number |
| T84433 |
20108-20110 |
IN |
denotes |
of |
| T75342 |
20111-20129 |
JJ |
denotes |
solvent-accessible |
| T8633 |
20130-20140 |
JJ |
denotes |
amino-acid |
| T96165 |
20141-20149 |
NNS |
denotes |
residues |
| T61859 |
20150-20152 |
IN |
denotes |
of |
| T96398 |
20153-20157 |
DT |
denotes |
each |
| T53031 |
20158-20168 |
JJ |
denotes |
respective |
| T13646 |
20169-20181 |
NN |
denotes |
glycoprotein |
| T34895 |
20182-20185 |
CC |
denotes |
and |
| T21412 |
20186-20193 |
VBD |
denotes |
plotted |
| T93327 |
20194-20198 |
DT |
denotes |
this |
| T37324 |
20199-20206 |
IN |
denotes |
against |
| T83132 |
20207-20219 |
NN |
denotes |
oligomannose |
| T17751 |
20220-20229 |
NN |
denotes |
abundance |
| T73372 |
20231-20232 |
DT |
denotes |
A |
| T11561 |
20233-20239 |
JJ |
denotes |
strong |
| T31010 |
20240-20251 |
NN |
denotes |
correlation |
| T21278 |
20252-20255 |
VBD |
denotes |
was |
| T95071 |
20256-20264 |
VBN |
denotes |
observed |
| T30414 |
20265-20266 |
-LRB- |
denotes |
( |
| T84041 |
20266-20272 |
NN |
denotes |
Fig. 6 |
| T23375 |
20272-20273 |
-RRB- |
denotes |
) |
| T37933 |
20274-20277 |
CC |
denotes |
and |
| T54604 |
20278-20285 |
NNS |
denotes |
viruses |
| T83021 |
20286-20298 |
RB |
denotes |
historically |
| T67339 |
20299-20309 |
VBN |
denotes |
classified |
| T1758 |
20310-20312 |
IN |
denotes |
as |
| T50624 |
20313-20321 |
NN |
denotes |
“evasion |
| T41175 |
20322-20331 |
NN |
denotes |
strong”56 |
| T26594 |
20332-20335 |
VBD |
denotes |
had |
| T17878 |
20336-20349 |
RB |
denotes |
significantly |
| T59830 |
20350-20358 |
JJ |
denotes |
elevated |
| T67014 |
20359-20365 |
NN |
denotes |
glycan |
| T83252 |
20366-20372 |
NN |
denotes |
shield |
| T44453 |
20373-20382 |
NNS |
denotes |
densities |
| T12305 |
20383-20386 |
CC |
denotes |
and |
| T84841 |
20387-20399 |
NN |
denotes |
oligomannose |
| T65772 |
20400-20409 |
NN |
denotes |
abundance |
| T36713 |
20409-20410 |
-COMMA- |
denotes |
, |
| T36054 |
20411-20416 |
WDT |
denotes |
which |
| T54589 |
20417-20428 |
VBZ |
denotes |
underscores |
| T77386 |
20429-20432 |
DT |
denotes |
the |
| T8708 |
20433-20443 |
NN |
denotes |
importance |
| T99300 |
20444-20446 |
IN |
denotes |
of |
| T3158 |
20447-20453 |
NN |
denotes |
glycan |
| T44352 |
20454-20463 |
NN |
denotes |
shielding |
| T8441 |
20464-20466 |
IN |
denotes |
in |
| T91196 |
20467-20473 |
JJ |
denotes |
immune |
| T54044 |
20474-20481 |
NN |
denotes |
evasion |
| T60202 |
20483-20487 |
NNP |
denotes |
Fig. |
| T35932 |
20488-20489 |
CD |
denotes |
6 |
| T52424 |
20490-20500 |
NN |
denotes |
Comparison |
| T33530 |
20501-20503 |
IN |
denotes |
of |
| T64406 |
20504-20507 |
DT |
denotes |
the |
| T54237 |
20508-20514 |
NN |
denotes |
glycan |
| T17551 |
20515-20522 |
NNS |
denotes |
shields |
| T16798 |
20523-20525 |
IN |
denotes |
of |
| T41253 |
20526-20531 |
JJ |
denotes |
viral |
| T25202 |
20532-20537 |
NN |
denotes |
class |
| T14464 |
20538-20539 |
CD |
denotes |
I |
| T85420 |
20540-20546 |
NN |
denotes |
fusion |
| T28685 |
20547-20555 |
NNS |
denotes |
proteins |
| T57548 |
20557-20563 |
NN |
denotes |
Glycan |
| T11420 |
20564-20570 |
NN |
denotes |
shield |
| T30294 |
20571-20580 |
NNS |
denotes |
densities |
| T78773 |
20581-20585 |
VBD |
denotes |
were |
| T51996 |
20586-20596 |
VBN |
denotes |
calculated |
| T60493 |
20597-20602 |
VBG |
denotes |
using |
| T24146 |
20603-20611 |
NNPS |
denotes |
Proteins |
| T7451 |
20611-20612 |
-COMMA- |
denotes |
, |
| T11968 |
20613-20623 |
NNP |
denotes |
Interfaces |
| T93687 |
20623-20624 |
-COMMA- |
denotes |
, |
| T97859 |
20625-20635 |
NNPS |
denotes |
Structures |
| T31999 |
20636-20639 |
CC |
denotes |
and |
| T70602 |
20640-20650 |
NNPS |
denotes |
Assemblies |
| T67118 |
20651-20652 |
-LRB- |
denotes |
( |
| T86788 |
20652-20656 |
NN |
denotes |
PISA |
| T23666 |
20656-20657 |
-RRB- |
denotes |
) |
| T93480 |
20657-20659 |
CD |
denotes |
83 |
| T54925 |
20660-20668 |
NNS |
denotes |
analyses |
| T13544 |
20669-20671 |
IN |
denotes |
of |
| T10473 |
20672-20677 |
RB |
denotes |
fully |
| T95681 |
20678-20690 |
VBN |
denotes |
glycosylated |
| T46270 |
20691-20697 |
NNS |
denotes |
models |
| T25318 |
20698-20700 |
IN |
denotes |
of |
| T63214 |
20701-20705 |
NNP |
denotes |
SARS |
| T36278 |
20706-20707 |
NNP |
denotes |
S |
| T38160 |
20707-20708 |
-COMMA- |
denotes |
, |
| T32901 |
20709-20713 |
NNP |
denotes |
MERS |
| T50082 |
20714-20715 |
NNP |
denotes |
S |
| T20315 |
20715-20716 |
-COMMA- |
denotes |
, |
| T26336 |
20717-20721 |
NNP |
denotes |
HKU1 |
| T80637 |
20722-20723 |
NNP |
denotes |
S |
| T28124 |
20723-20724 |
-COMMA- |
denotes |
, |
| T48490 |
20725-20729 |
NN |
denotes |
LASV |
| T53169 |
20730-20733 |
NN |
denotes |
GPC |
| T70489 |
20733-20734 |
-COMMA- |
denotes |
, |
| T36851 |
20735-20740 |
NN |
denotes |
HIV-1 |
| T61005 |
20741-20744 |
NN |
denotes |
Env |
| T62312 |
20745-20746 |
-LRB- |
denotes |
( |
| T36158 |
20746-20751 |
NN |
denotes |
BG505 |
| T19207 |
20751-20752 |
-RRB- |
denotes |
) |
| T1909 |
20752-20753 |
-COMMA- |
denotes |
, |
| T16967 |
20754-20763 |
NN |
denotes |
Influenza |
| T17288 |
20764-20768 |
NN |
denotes |
H3N2 |
| T64807 |
20769-20782 |
NN |
denotes |
hemagglutinin |
| T69427 |
20783-20784 |
-LRB- |
denotes |
( |
| T33012 |
20784-20792 |
NNP |
denotes |
Victoria |
| T31397 |
20793-20797 |
CD |
denotes |
2011 |
| T95304 |
20797-20798 |
-RRB- |
denotes |
) |
| T61501 |
20798-20799 |
-COMMA- |
denotes |
, |
| T78843 |
20800-20803 |
NN |
denotes |
SIV |
| T53051 |
20804-20807 |
NNP |
denotes |
Env |
| T95730 |
20808-20809 |
-LRB- |
denotes |
( |
| T35725 |
20809-20812 |
NN |
denotes |
PDB |
| T46991 |
20813-20815 |
NN |
denotes |
ID |
| T12133 |
20816-20820 |
NN |
denotes |
5X58 |
| T34645 |
20820-20821 |
-COMMA- |
denotes |
, |
| T32072 |
20822-20826 |
NN |
denotes |
5X59 |
| T39600 |
20826-20827 |
-COMMA- |
denotes |
, |
| T65590 |
20828-20832 |
NN |
denotes |
5I08 |
| T19879 |
20832-20833 |
-COMMA- |
denotes |
, |
| T61708 |
20834-20838 |
NN |
denotes |
5VK2 |
| T80173 |
20838-20839 |
-COMMA- |
denotes |
, |
| T86385 |
20840-20844 |
NN |
denotes |
4ZMJ |
| T31925 |
20844-20845 |
-COMMA- |
denotes |
, |
| T78881 |
20846-20850 |
NN |
denotes |
4O5N |
| T64135 |
20850-20851 |
-COMMA- |
denotes |
, |
| T30171 |
20852-20856 |
NN |
denotes |
6OHY |
| T91114 |
20856-20857 |
-COMMA- |
denotes |
, |
| T4958 |
20858-20870 |
RB |
denotes |
respectively |
| T39966 |
20870-20871 |
-RRB- |
denotes |
) |
| T89368 |
20871-20884 |
CD |
denotes |
9,11,53,84–86 |
| T57630 |
20886-20898 |
NN |
denotes |
Oligomannose |
| T21025 |
20899-20909 |
NNS |
denotes |
abundances |
| T24463 |
20910-20912 |
IN |
denotes |
of |
| T96910 |
20913-20918 |
JJ |
denotes |
viral |
| T1932 |
20919-20932 |
NNS |
denotes |
glycoproteins |
| T11498 |
20933-20937 |
VBD |
denotes |
were |
| T36644 |
20938-20949 |
VBN |
denotes |
ascertained |
| T73246 |
20950-20952 |
IN |
denotes |
by |
| T1782 |
20953-20963 |
NN |
denotes |
HILIC-UPLC |
| T3180 |
20964-20972 |
NN |
denotes |
analysis |
| T62295 |
20973-20975 |
IN |
denotes |
of |
| T78639 |
20976-20982 |
NN |
denotes |
PNGase |
| T58794 |
20983-20984 |
NN |
denotes |
F |
| T67409 |
20985-20993 |
VBN |
denotes |
released |
| T15765 |
20994-21002 |
JJ |
denotes |
N-linked |
| T33026 |
21003-21010 |
NNS |
denotes |
glycans |
| T60951 |
21011-21015 |
WDT |
denotes |
that |
| T45752 |
21016-21020 |
VBD |
denotes |
were |
| T96739 |
21021-21034 |
RB |
denotes |
fluorescently |
| T44762 |
21035-21043 |
VBN |
denotes |
labelled |
| T97123 |
21044-21048 |
IN |
denotes |
with |
| T94571 |
21049-21069 |
NN |
denotes |
procainamide24,45,53 |
| T49839 |
21070-21071 |
-LRB- |
denotes |
( |
| T5501 |
21071-21073 |
NN |
denotes |
SI |
| T78348 |
21074-21080 |
NN |
denotes |
Fig. 5 |
| T93024 |
21080-21081 |
-RRB- |
denotes |
) |
| T81346 |
21083-21086 |
DT |
denotes |
The |
| T66936 |
21087-21093 |
NN |
denotes |
number |
| T36773 |
21094-21096 |
IN |
denotes |
of |
| T76460 |
21097-21107 |
JJ |
denotes |
amino-acid |
| T27945 |
21108-21116 |
NNS |
denotes |
residues |
| T75621 |
21117-21128 |
VBG |
denotes |
interacting |
| T84066 |
21129-21133 |
IN |
denotes |
with |
| T20906 |
21134-21142 |
JJ |
denotes |
N-linked |
| T54866 |
21143-21150 |
NNS |
denotes |
glycans |
| T73735 |
21151-21154 |
VBD |
denotes |
was |
| T12725 |
21155-21162 |
VBN |
denotes |
divided |
| T71326 |
21163-21165 |
IN |
denotes |
by |
| T33187 |
21166-21169 |
DT |
denotes |
the |
| T90192 |
21170-21176 |
NN |
denotes |
number |
| T62752 |
21177-21179 |
IN |
denotes |
of |
| T61364 |
21180-21198 |
JJ |
denotes |
solvent-accessible |
| T68346 |
21199-21209 |
JJ |
denotes |
amino-acid |
| T61476 |
21210-21218 |
NNS |
denotes |
residues |
| T43495 |
21219-21221 |
IN |
denotes |
of |
| T46241 |
21222-21225 |
DT |
denotes |
the |
| T24762 |
21226-21238 |
NN |
denotes |
glycoprotein |
| T53426 |
21239-21241 |
IN |
denotes |
as |
| T85566 |
21242-21243 |
DT |
denotes |
a |
| T28528 |
21244-21251 |
NN |
denotes |
measure |
| T60922 |
21252-21255 |
IN |
denotes |
for |
| T57613 |
21256-21262 |
JJ |
denotes |
global |
| T92947 |
21263-21269 |
NN |
denotes |
glycan |
| T81164 |
21270-21276 |
NN |
denotes |
shield |
| T10370 |
21277-21284 |
NN |
denotes |
density |
| T61338 |
21286-21289 |
DT |
denotes |
All |
| T48920 |
21290-21295 |
JJ |
denotes |
viral |
| T68543 |
21296-21309 |
NNS |
denotes |
glycoproteins |
| T82274 |
21310-21318 |
VBN |
denotes |
analysed |
| T26853 |
21319-21323 |
VBD |
denotes |
were |
| T71248 |
21324-21333 |
VBN |
denotes |
expressed |
| T33142 |
21334-21336 |
IN |
denotes |
as |
| T69877 |
21337-21344 |
NNS |
denotes |
trimers |
| T70780 |
21345-21347 |
IN |
denotes |
in |
| T61720 |
21348-21355 |
NN |
denotes |
HEK293F |
| T11163 |
21356-21361 |
NNS |
denotes |
cells |
| T6955 |
21362-21367 |
RB |
denotes |
apart |
| T40144 |
21368-21372 |
IN |
denotes |
from |
| T86025 |
21373-21377 |
NN |
denotes |
LASV |
| T38606 |
21378-21381 |
NN |
denotes |
GPC |
| T52914 |
21381-21382 |
-COMMA- |
denotes |
, |
| T35666 |
21383-21388 |
WDT |
denotes |
which |
| T47548 |
21389-21392 |
VBD |
denotes |
was |
| T56105 |
21393-21400 |
VBN |
denotes |
derived |
| T54764 |
21401-21405 |
IN |
denotes |
from |
| T18669 |
21406-21416 |
JJ |
denotes |
virus-like |
| T49812 |
21417-21426 |
NNS |
denotes |
particles |
| T85286 |
21427-21431 |
IN |
denotes |
from |
| T2491 |
21432-21443 |
JJ |
denotes |
Madin-Darby |
| T81144 |
21444-21450 |
JJ |
denotes |
canine |
| T79381 |
21451-21457 |
NN |
denotes |
kidney |
| T4581 |
21458-21460 |
CD |
denotes |
II |
| T55061 |
21461-21466 |
NNS |
denotes |
cells |
| T77073 |
21468-21475 |
IN |
denotes |
Whether |
| T67807 |
21476-21479 |
DT |
denotes |
the |
| T93664 |
21480-21490 |
JJ |
denotes |
restricted |
| T45320 |
21491-21497 |
NN |
denotes |
glycan |
| T66354 |
21498-21507 |
NN |
denotes |
shielding |
| T51052 |
21508-21516 |
VBN |
denotes |
observed |
| T89745 |
21517-21519 |
IN |
denotes |
on |
| T75541 |
21520-21533 |
NNS |
denotes |
coronaviruses |
| T6297 |
21534-21536 |
VBZ |
denotes |
is |
| T72680 |
21537-21543 |
VBN |
denotes |
linked |
| T21071 |
21544-21546 |
TO |
denotes |
to |
| T25999 |
21547-21550 |
DT |
denotes |
the |
| T64543 |
21551-21559 |
NN |
denotes |
zoonosis |
| T98572 |
21560-21562 |
IN |
denotes |
of |
| T45232 |
21563-21566 |
DT |
denotes |
the |
| T83454 |
21567-21576 |
NNS |
denotes |
pathogens |
| T22467 |
21577-21579 |
VBZ |
denotes |
is |
| T99216 |
21580-21587 |
JJ |
denotes |
unknown |
| T96797 |
21589-21596 |
RB |
denotes |
However |
| T9612 |
21596-21597 |
-COMMA- |
denotes |
, |
| T50771 |
21598-21600 |
PRP |
denotes |
it |
| T66305 |
21601-21603 |
VBZ |
denotes |
is |
| T45372 |
21604-21612 |
VBG |
denotes |
tempting |
| T20635 |
21613-21615 |
TO |
denotes |
to |
| T10053 |
21616-21625 |
VB |
denotes |
speculate |
| T71408 |
21625-21626 |
-COMMA- |
denotes |
, |
| T41377 |
21627-21630 |
IN |
denotes |
for |
| T63997 |
21631-21638 |
NN |
denotes |
example |
| T55394 |
21638-21639 |
-COMMA- |
denotes |
, |
| T32869 |
21640-21644 |
IN |
denotes |
that |
| T14682 |
21645-21649 |
NNS |
denotes |
MERS |
| T19094 |
21650-21653 |
VBZ |
denotes |
has |
| T21668 |
21654-21657 |
RB |
denotes |
not |
| T76353 |
21658-21665 |
VBN |
denotes |
evolved |
| T45819 |
21666-21667 |
DT |
denotes |
a |
| T85678 |
21668-21673 |
JJ |
denotes |
dense |
| T77537 |
21674-21680 |
NN |
denotes |
shield |
| T26368 |
21681-21686 |
IN |
denotes |
since |
| T68778 |
21687-21689 |
PRP |
denotes |
it |
| T46258 |
21690-21695 |
MD |
denotes |
would |
| T84900 |
21696-21699 |
RB |
denotes |
not |
| T11621 |
21700-21705 |
VB |
denotes |
offer |
| T10630 |
21706-21708 |
RB |
denotes |
as |
| T89313 |
21709-21713 |
JJ |
denotes |
much |
| T61578 |
21714-21716 |
IN |
denotes |
of |
| T35149 |
21717-21718 |
DT |
denotes |
a |
| T47037 |
21719-21729 |
JJ |
denotes |
protective |
| T11435 |
21730-21739 |
NN |
denotes |
advantage |
| T31174 |
21740-21747 |
IN |
denotes |
against |
| T44925 |
21748-21753 |
NN |
denotes |
camel |
| T15627 |
21754-21764 |
NNS |
denotes |
nanobodies |
| T39650 |
21765-21766 |
-LRB- |
denotes |
( |
| T37112 |
21766-21770 |
RB |
denotes |
also |
| T10045 |
21771-21776 |
VBN |
denotes |
known |
| T88998 |
21777-21779 |
IN |
denotes |
as |
| T18704 |
21780-21793 |
JJ |
denotes |
single-domain |
| T56245 |
21794-21804 |
NNS |
denotes |
antibodies |
| T77976 |
21804-21805 |
-RRB- |
denotes |
) |
| T64574 |
21806-21811 |
WDT |
denotes |
which |
| T32529 |
21812-21817 |
MD |
denotes |
could |
| T62658 |
21818-21822 |
RBR |
denotes |
more |
| T74010 |
21823-21829 |
RB |
denotes |
easily |
| T43286 |
21830-21839 |
VB |
denotes |
penetrate |
| T94995 |
21840-21842 |
PRP |
denotes |
it |
| T58389 |
21844-21857 |
NN |
denotes |
Investigation |
| T28787 |
21858-21860 |
IN |
denotes |
of |
| T88817 |
21861-21864 |
DT |
denotes |
the |
| T51212 |
21865-21869 |
NN |
denotes |
host |
| T22448 |
21870-21876 |
JJ |
denotes |
immune |
| T97014 |
21877-21885 |
NN |
denotes |
response |
| T84588 |
21886-21888 |
TO |
denotes |
to |
| T22349 |
21889-21896 |
NNS |
denotes |
viruses |
| T85837 |
21897-21899 |
IN |
denotes |
in |
| T29947 |
21900-21905 |
PRP-DOLLAR- |
denotes |
their |
| T60633 |
21906-21913 |
JJ |
denotes |
natural |
| T20023 |
21914-21924 |
NNS |
denotes |
reservoirs |
| T98213 |
21925-21928 |
MD |
denotes |
may |
| T89551 |
21929-21934 |
VB |
denotes |
offer |
| T67690 |
21935-21936 |
DT |
denotes |
a |
| T79346 |
21937-21942 |
NN |
denotes |
route |
| T99997 |
21943-21945 |
TO |
denotes |
to |
| T77964 |
21946-21959 |
VBG |
denotes |
understanding |
| T72412 |
21960-21963 |
WRB |
denotes |
why |
| T1666 |
21964-21975 |
NN |
denotes |
coronavirus |
| T33538 |
21976-21989 |
NN |
denotes |
glycosylation |
| T88529 |
21990-21994 |
VBZ |
denotes |
does |
| T92394 |
21995-21998 |
RB |
denotes |
not |
| T23766 |
21999-22004 |
VB |
denotes |
reach |
| T96858 |
22005-22008 |
DT |
denotes |
the |
| T3894 |
22009-22016 |
NN |
denotes |
density |
| T52698 |
22017-22019 |
IN |
denotes |
of |
| T42360 |
22020-22025 |
JJ |
denotes |
other |
| T26744 |
22026-22033 |
NNS |
denotes |
viruses |
| T99485 |
22034-22038 |
JJ |
denotes |
such |
| T82055 |
22039-22041 |
IN |
denotes |
as |
| T18913 |
22042-22047 |
NN |
denotes |
HIV-1 |
| T64649 |
22049-22051 |
IN |
denotes |
In |
| T2320 |
22052-22060 |
NN |
denotes |
addition |
| T78686 |
22060-22061 |
-COMMA- |
denotes |
, |
| T83984 |
22062-22064 |
PRP |
denotes |
it |
| T27307 |
22065-22068 |
MD |
denotes |
may |
| T34676 |
22069-22071 |
VB |
denotes |
be |
| T94812 |
22072-22076 |
IN |
denotes |
that |
| T62851 |
22077-22087 |
JJ |
denotes |
functional |
| T59734 |
22088-22099 |
NNS |
denotes |
constraints |
| T18450 |
22099-22100 |
-COMMA- |
denotes |
, |
| T92297 |
22101-22105 |
JJ |
denotes |
such |
| T82162 |
22106-22108 |
IN |
denotes |
as |
| T65049 |
22109-22120 |
VBG |
denotes |
maintaining |
| T73605 |
22121-22132 |
NN |
denotes |
flexibility |
| T82163 |
22133-22135 |
IN |
denotes |
of |
| T95489 |
22136-22139 |
DT |
denotes |
the |
| T80363 |
22140-22156 |
JJ |
denotes |
receptor-binding |
| T16712 |
22157-22164 |
NNS |
denotes |
domains |
| T51721 |
22164-22165 |
-COMMA- |
denotes |
, |
| T50969 |
22166-22171 |
VBP |
denotes |
limit |
| T82950 |
22172-22175 |
DT |
denotes |
the |
| T89747 |
22176-22185 |
NN |
denotes |
accretion |
| T86415 |
22186-22188 |
IN |
denotes |
of |
| T7969 |
22189-22196 |
NNS |
denotes |
glycans |
| T9896 |
22197-22199 |
IN |
denotes |
on |
| T98585 |
22200-22211 |
NN |
denotes |
coronavirus |
| T75554 |
22212-22218 |
NNS |
denotes |
spikes |
| T19065 |
22218-22219 |
-COMMA- |
denotes |
, |
| T16194 |
22220-22225 |
WDT |
denotes |
which |
| T68142 |
22226-22231 |
MD |
denotes |
would |
| T16555 |
22232-22238 |
VB |
denotes |
render |
| T87051 |
22239-22241 |
PRP |
denotes |
it |
| T66339 |
22242-22251 |
JJ |
denotes |
incapable |
| T85203 |
22252-22254 |
IN |
denotes |
of |
| T82847 |
22255-22265 |
VBG |
denotes |
performing |
| T94649 |
22266-22269 |
PRP-DOLLAR- |
denotes |
its |
| T29264 |
22270-22277 |
JJ |
denotes |
primary |
| T84155 |
22278-22287 |
NNS |
denotes |
functions |
| T77249 |
22287-22288 |
-COMMA- |
denotes |
, |
| T70958 |
22289-22298 |
VBG |
denotes |
including |
| T87179 |
22299-22315 |
JJ |
denotes |
receptor-binding |
| T16494 |
22316-22319 |
CC |
denotes |
and |
| T62341 |
22320-22328 |
NN |
denotes |
membrane |
| T47272 |
22329-22335 |
NN |
denotes |
fusion |
| T74425 |
22337-22341 |
DT |
denotes |
This |
| T28812 |
22342-22352 |
NN |
denotes |
phenomenon |
| T23330 |
22353-22356 |
VBZ |
denotes |
has |
| T79957 |
22357-22361 |
VBN |
denotes |
been |
| T88747 |
22362-22370 |
VBN |
denotes |
observed |
| T37978 |
22371-22373 |
IN |
denotes |
on |
| T66756 |
22374-22379 |
JJ |
denotes |
other |
| T49403 |
22380-22385 |
JJ |
denotes |
viral |
| T71298 |
22386-22399 |
NNS |
denotes |
glycoproteins |
| T42034 |
22399-22400 |
-COMMA- |
denotes |
, |
| T50579 |
22401-22410 |
VBG |
denotes |
including |
| T39729 |
22411-22420 |
NN |
denotes |
influenza |
| T5616 |
22421-22424 |
NNS |
denotes |
HAs |
| T5660 |
22424-22425 |
-COMMA- |
denotes |
, |
| T25906 |
22426-22431 |
WRB |
denotes |
where |
| T12419 |
22432-22437 |
EX |
denotes |
there |
| T16685 |
22438-22440 |
VBZ |
denotes |
is |
| T69838 |
22441-22442 |
DT |
denotes |
a |
| T24412 |
22443-22448 |
NN |
denotes |
limit |
| T2009 |
22449-22451 |
TO |
denotes |
to |
| T53210 |
22452-22455 |
DT |
denotes |
the |
| T7550 |
22456-22468 |
NN |
denotes |
accumulation |
| T70799 |
22469-22471 |
IN |
denotes |
of |
| T50138 |
22472-22485 |
NN |
denotes |
glycosylation |
| T17645 |
22486-22491 |
NNS |
denotes |
sites |
| T91429 |
22492-22496 |
WDT |
denotes |
that |
| T69288 |
22497-22500 |
MD |
denotes |
can |
| T77299 |
22501-22503 |
VB |
denotes |
be |
| T39985 |
22504-22516 |
VBN |
denotes |
incorporated |
| T22591 |
22517-22519 |
IN |
denotes |
in |
| T39676 |
22520-22529 |
NN |
denotes |
vivo57,58 |
| T98764 |
22529-22530 |
-COMMA- |
denotes |
, |
| T66750 |
22531-22539 |
VBN |
denotes |
compared |
| T34506 |
22540-22544 |
IN |
denotes |
with |
| T30497 |
22545-22547 |
IN |
denotes |
in |
| T49179 |
22548-22555 |
NN |
denotes |
vitro59 |
| T8001 |
22555-22556 |
-COMMA- |
denotes |
, |
| T19500 |
22557-22561 |
IN |
denotes |
with |
| T55151 |
22562-22566 |
NN |
denotes |
H3N2 |
| T55814 |
22567-22570 |
CC |
denotes |
and |
| T64906 |
22571-22575 |
NN |
denotes |
H1N1 |
| T93681 |
22576-22579 |
VBZ |
denotes |
HAs |
| T72733 |
22580-22589 |
VBG |
denotes |
replacing |
| T10927 |
22590-22598 |
VBG |
denotes |
existing |
| T23904 |
22599-22603 |
NNS |
denotes |
PNGs |
| T45261 |
22604-22610 |
RB |
denotes |
rather |
| T77923 |
22611-22615 |
IN |
denotes |
than |
| T40157 |
22616-22627 |
RB |
denotes |
continually |
| T93082 |
22628-22634 |
VBG |
denotes |
adding |
| T56943 |
22635-22639 |
PRP |
denotes |
them |
| T51235 |
22640-22644 |
IN |
denotes |
upon |
| T22651 |
22645-22648 |
DT |
denotes |
the |
| T77822 |
22649-22666 |
NN |
denotes |
glycoprotein22,58 |
| T55217 |
22668-22671 |
DT |
denotes |
The |
| T19555 |
22672-22682 |
NN |
denotes |
importance |
| T26714 |
22683-22685 |
IN |
denotes |
of |
| T3445 |
22686-22699 |
NN |
denotes |
glycosylation |
| T95262 |
22700-22702 |
IN |
denotes |
in |
| T42577 |
22703-22713 |
NN |
denotes |
modulation |
| T48803 |
22714-22716 |
IN |
denotes |
of |
| T81500 |
22717-22722 |
JJ |
denotes |
viral |
| T5930 |
22723-22734 |
NN |
denotes |
infectivity |
| T8049 |
22735-22738 |
CC |
denotes |
and |
| T70719 |
22739-22745 |
JJ |
denotes |
immune |
| T49977 |
22746-22755 |
NNS |
denotes |
responses |
| T93956 |
22756-22760 |
VBP |
denotes |
have |
| T11993 |
22761-22765 |
RB |
denotes |
also |
| T1601 |
22766-22770 |
VBN |
denotes |
been |
| T74546 |
22771-22783 |
VBN |
denotes |
investigated |
| T66965 |
22784-22790 |
IN |
denotes |
during |
| T20256 |
22791-22800 |
NN |
denotes |
influenza |
| T50741 |
22801-22808 |
NN |
denotes |
vaccine |
| T54786 |
22809-22822 |
NN |
denotes |
research22,60 |
| T60387 |
22823-22826 |
CC |
denotes |
and |
| T65945 |
22827-22833 |
MD |
denotes |
should |
| T90413 |
22834-22836 |
VB |
denotes |
be |
| T59672 |
22837-22847 |
VBN |
denotes |
considered |
| T67170 |
22848-22850 |
IN |
denotes |
in |
| T43948 |
22851-22862 |
NN |
denotes |
coronavirus |
| T96785 |
22863-22870 |
NN |
denotes |
vaccine |
| T78856 |
22871-22879 |
NN |
denotes |
research |
| T92680 |
22881-22885 |
RBR |
denotes |
More |
| T84481 |
22886-22895 |
RB |
denotes |
topically |
| T70792 |
22895-22896 |
-COMMA- |
denotes |
, |
| T23248 |
22897-22899 |
PRP |
denotes |
it |
| T53506 |
22900-22902 |
VBZ |
denotes |
is |
| T18888 |
22903-22914 |
JJ |
denotes |
interesting |
| T12601 |
22915-22917 |
TO |
denotes |
to |
| T38716 |
22918-22922 |
VB |
denotes |
note |
| T31921 |
22923-22926 |
DT |
denotes |
the |
| T52475 |
22927-22939 |
NN |
denotes |
conservation |
| T58850 |
22940-22942 |
IN |
denotes |
of |
| T72458 |
22943-22951 |
JJ |
denotes |
N-linked |
| T35369 |
22952-22965 |
NN |
denotes |
glycosylation |
| T60774 |
22966-22971 |
NNS |
denotes |
sites |
| T17084 |
22972-22974 |
IN |
denotes |
on |
| T40757 |
22975-22976 |
NN |
denotes |
S |
| T18965 |
22977-22985 |
NNS |
denotes |
proteins |
| T72137 |
22986-22990 |
IN |
denotes |
from |
| T71306 |
22991-22994 |
DT |
denotes |
the |
| T25653 |
22995-23005 |
NN |
denotes |
SARS-CoV-2 |
| T82634 |
23006-23009 |
CC |
denotes |
and |
| T90138 |
23010-23014 |
NN |
denotes |
SARS |
| T79086 |
23015-23016 |
-LRB- |
denotes |
( |
| T21819 |
23016-23018 |
NN |
denotes |
SI |
| T4098 |
23019-23025 |
NN |
denotes |
Fig. 6 |
| T37852 |
23025-23026 |
-RRB- |
denotes |
) |
| T34122 |
23028-23038 |
NN |
denotes |
SARS-CoV-2 |
| T47078 |
23039-23048 |
VBZ |
denotes |
possesses |
| T64573 |
23049-23050 |
DT |
denotes |
a |
| T60437 |
23051-23056 |
NN |
denotes |
total |
| T28667 |
23057-23059 |
IN |
denotes |
of |
| T12092 |
23060-23062 |
CD |
denotes |
22 |
| T1640 |
23063-23071 |
JJ |
denotes |
N-linked |
| T97157 |
23072-23078 |
NN |
denotes |
glycan |
| T11869 |
23079-23084 |
NNS |
denotes |
sites |
| T81728 |
23085-23093 |
VBN |
denotes |
compared |
| T53746 |
23094-23098 |
IN |
denotes |
with |
| T64999 |
23099-23101 |
CD |
denotes |
23 |
| T3044 |
23102-23104 |
IN |
denotes |
on |
| T27983 |
23105-23109 |
NNP |
denotes |
SARS |
| T70372 |
23109-23110 |
-COMMA- |
denotes |
, |
| T36523 |
23111-23115 |
IN |
denotes |
with |
| T81512 |
23116-23118 |
CD |
denotes |
18 |
| T55641 |
23119-23121 |
IN |
denotes |
of |
| T31809 |
23122-23127 |
DT |
denotes |
these |
| T30346 |
23128-23133 |
NNS |
denotes |
sites |
| T33229 |
23134-23139 |
VBG |
denotes |
being |
| T95497 |
23140-23142 |
IN |
denotes |
in |
| T81137 |
23143-23149 |
NN |
denotes |
common |
| T99058 |
23151-23153 |
IN |
denotes |
As |
| T67481 |
23154-23158 |
JJ |
denotes |
such |
| T5512 |
23158-23159 |
-COMMA- |
denotes |
, |
| T56317 |
23160-23162 |
PRP |
denotes |
it |
| T83032 |
23163-23165 |
VBZ |
denotes |
is |
| T6892 |
23166-23172 |
JJ |
denotes |
likely |
| T46550 |
23173-23177 |
IN |
denotes |
that |
| T32694 |
23178-23183 |
DT |
denotes |
these |
| T45067 |
23184-23191 |
NNS |
denotes |
glycans |
| T82922 |
23192-23194 |
IN |
denotes |
on |
| T78450 |
23195-23199 |
DT |
denotes |
this |
| T70467 |
23200-23205 |
JJ |
denotes |
novel |
| T54943 |
23206-23217 |
NN |
denotes |
coronavirus |
| T82041 |
23218-23223 |
MD |
denotes |
would |
| T38496 |
23224-23230 |
VB |
denotes |
shield |
| T40453 |
23231-23238 |
JJ |
denotes |
similar |
| T78152 |
23239-23250 |
JJ |
denotes |
immunogenic |
| T36034 |
23251-23259 |
NNS |
denotes |
epitopes |
| T43430 |
23260-23264 |
WDT |
denotes |
that |
| T42643 |
23265-23268 |
VBP |
denotes |
are |
| T34663 |
23269-23277 |
VBN |
denotes |
observed |
| T28338 |
23278-23280 |
IN |
denotes |
on |
| T42537 |
23281-23285 |
NNP |
denotes |
SARS |
| T28404 |
23286-23288 |
NNP |
denotes |
S. |
| T34718 |
23289-23291 |
IN |
denotes |
As |
| T3102 |
23292-23300 |
VBN |
denotes |
expected |
| T14875 |
23300-23301 |
-COMMA- |
denotes |
, |
| T72037 |
23302-23306 |
JJS |
denotes |
most |
| T23602 |
23307-23309 |
IN |
denotes |
of |
| T78209 |
23310-23313 |
DT |
denotes |
the |
| T75405 |
23314-23325 |
NNS |
denotes |
differences |
| T7434 |
23326-23333 |
IN |
denotes |
between |
| T54679 |
23334-23337 |
DT |
denotes |
the |
| T36690 |
23338-23341 |
CD |
denotes |
two |
| T10541 |
23342-23349 |
NNS |
denotes |
viruses |
| T22099 |
23350-23353 |
VBP |
denotes |
are |
| T77577 |
23354-23362 |
VBN |
denotes |
observed |
| T80845 |
23363-23365 |
IN |
denotes |
on |
| T35913 |
23366-23369 |
DT |
denotes |
the |
| T42862 |
23370-23372 |
NN |
denotes |
S1 |
| T82481 |
23373-23380 |
NN |
denotes |
subunit |
| T63639 |
23380-23381 |
-COMMA- |
denotes |
, |
| T95917 |
23382-23385 |
JJ |
denotes |
due |
| T19623 |
23386-23388 |
TO |
denotes |
to |
| T39634 |
23389-23392 |
PRP-DOLLAR- |
denotes |
its |
| T91852 |
23393-23404 |
NN |
denotes |
amenability |
| T93743 |
23405-23407 |
TO |
denotes |
to |
| T96851 |
23408-23421 |
NNS |
denotes |
substitutions |
| T53841 |
23422-23427 |
IN |
denotes |
while |
| T23506 |
23428-23433 |
RB |
denotes |
still |
| T19959 |
23434-23443 |
VBG |
denotes |
remaining |
| T60128 |
23444-23456 |
RB |
denotes |
functionally |
| T58264 |
23457-23466 |
JJ |
denotes |
competent |
| T45174 |
23468-23479 |
RB |
denotes |
Furthermore |
| T77108 |
23479-23480 |
-COMMA- |
denotes |
, |
| T23034 |
23481-23487 |
JJ |
denotes |
likely |
| T28413 |
23488-23495 |
NNS |
denotes |
targets |
| T16688 |
23496-23499 |
IN |
denotes |
for |
| T51805 |
23500-23503 |
DT |
denotes |
the |
| T98975 |
23504-23512 |
NN |
denotes |
majority |
| T23520 |
23513-23515 |
IN |
denotes |
of |
| T89744 |
23516-23526 |
NNS |
denotes |
antibodies |
| T37340 |
23527-23536 |
VBG |
denotes |
targeting |
| T85444 |
23537-23540 |
DT |
denotes |
the |
| T12203 |
23541-23546 |
NN |
denotes |
spike |
| T30887 |
23547-23550 |
VBP |
denotes |
are |
| T9951 |
23551-23558 |
JJ |
denotes |
located |
| T15001 |
23559-23561 |
IN |
denotes |
on |
| T46529 |
23562-23564 |
NN |
denotes |
S1 |
| T56103 |
23564-23565 |
-COMMA- |
denotes |
, |
| T81494 |
23566-23575 |
VBG |
denotes |
resulting |
| T44486 |
23576-23578 |
IN |
denotes |
in |
| T32445 |
23579-23586 |
JJR |
denotes |
greater |
| T72703 |
23587-23593 |
NNS |
denotes |
levels |
| T40990 |
23594-23596 |
IN |
denotes |
of |
| T38229 |
23597-23603 |
JJ |
denotes |
immune |
| T43357 |
23604-23612 |
NN |
denotes |
pressure |
| T59397 |
23613-23617 |
IN |
denotes |
upon |
| T26191 |
23618-23622 |
DT |
denotes |
this |
| T33036 |
23623-23630 |
NN |
denotes |
subunit |
| T97000 |
23632-23636 |
DT |
denotes |
This |
| T64538 |
23637-23643 |
NN |
denotes |
notion |
| T59288 |
23644-23646 |
VBZ |
denotes |
is |
| T47385 |
23647-23654 |
RBR |
denotes |
further |
| T35201 |
23655-23664 |
VBN |
denotes |
reflected |
| T72056 |
23665-23667 |
IN |
denotes |
in |
| T18104 |
23668-23673 |
NNS |
denotes |
terms |
| T34570 |
23674-23676 |
IN |
denotes |
of |
| T18734 |
23677-23690 |
NN |
denotes |
glycosylation |
| T57766 |
23690-23691 |
-COMMA- |
denotes |
, |
| T66534 |
23692-23696 |
IN |
denotes |
with |
| T36486 |
23697-23700 |
DT |
denotes |
all |
| T71292 |
23701-23703 |
IN |
denotes |
of |
| T8985 |
23704-23707 |
DT |
denotes |
the |
| T61275 |
23708-23714 |
NN |
denotes |
glycan |
| T2410 |
23715-23720 |
NNS |
denotes |
sites |
| T35106 |
23721-23730 |
VBN |
denotes |
conserved |
| T58672 |
23731-23733 |
IN |
denotes |
on |
| T57713 |
23734-23737 |
DT |
denotes |
the |
| T22974 |
23738-23740 |
NN |
denotes |
S2 |
| T26472 |
23741-23748 |
NN |
denotes |
subunit |
| T18939 |
23749-23756 |
IN |
denotes |
between |
| T72173 |
23757-23761 |
NN |
denotes |
SARS |
| T72299 |
23762-23765 |
CC |
denotes |
and |
| T10006 |
23766-23776 |
NN |
denotes |
SARS-CoV-2 |
| T58557 |
23776-23777 |
-COMMA- |
denotes |
, |
| T83864 |
23778-23785 |
IN |
denotes |
whereas |
| T99079 |
23786-23789 |
DT |
denotes |
the |
| T3040 |
23790-23792 |
NN |
denotes |
S1 |
| T2354 |
23793-23800 |
NN |
denotes |
subunit |
| T23968 |
23801-23809 |
VBZ |
denotes |
exhibits |
| T71933 |
23810-23816 |
NN |
denotes |
glycan |
| T60903 |
23817-23821 |
NN |
denotes |
site |
| T37762 |
23822-23831 |
NNS |
denotes |
additions |
| T91373 |
23832-23835 |
CC |
denotes |
and |
| T25121 |
23836-23845 |
NNS |
denotes |
deletions |
| T22092 |
23846-23847 |
-LRB- |
denotes |
( |
| T71875 |
23847-23849 |
NN |
denotes |
SI |
| T23058 |
23850-23856 |
NN |
denotes |
Fig. 7 |
| T18793 |
23856-23857 |
-RRB- |
denotes |
) |
| T76427 |
23859-23872 |
JJ |
denotes |
Bioinformatic |
| T77800 |
23873-23881 |
NN |
denotes |
analysis |
| T78537 |
23882-23884 |
IN |
denotes |
of |
| T86297 |
23885-23892 |
JJ |
denotes |
current |
| T80371 |
23893-23903 |
NN |
denotes |
SARS-CoV-2 |
| T13595 |
23904-23909 |
NN |
denotes |
spike |
| T39941 |
23910-23915 |
NNS |
denotes |
genes |
| T50763 |
23916-23917 |
-LRB- |
denotes |
( |
| T65176 |
23917-23924 |
NN |
denotes |
n = 566 |
| T2438 |
23925-23927 |
IN |
denotes |
as |
| T93347 |
23928-23930 |
IN |
denotes |
of |
| T69209 |
23931-23933 |
CD |
denotes |
17 |
| T15871 |
23934-23939 |
NNP |
denotes |
March |
| T73572 |
23940-23944 |
CD |
denotes |
2020 |
| T57682 |
23944-23945 |
-RRB- |
denotes |
) |
| T37387 |
23946-23950 |
IN |
denotes |
from |
| T97769 |
23951-23963 |
NN |
denotes |
nextstrain61 |
| T59510 |
23964-23965 |
-LRB- |
denotes |
( |
| T27017 |
23965-23970 |
NNS |
denotes |
https |
| T63488 |
23970-23971 |
-COLON- |
denotes |
: |
| T93568 |
23971-23992 |
LS |
denotes |
//nextstrain.org/ncov |
| T43920 |
23992-23993 |
-RRB- |
denotes |
) |
| T64664 |
23994-24002 |
VBD |
denotes |
revealed |
| T48510 |
24003-24006 |
JJ |
denotes |
low |
| T63332 |
24007-24015 |
NN |
denotes |
sequence |
| T32624 |
24016-24025 |
NN |
denotes |
diversity |
| T57322 |
24026-24029 |
CC |
denotes |
and |
| T27673 |
24030-24032 |
DT |
denotes |
no |
| T84080 |
24033-24040 |
NNS |
denotes |
changes |
| T83739 |
24041-24043 |
IN |
denotes |
in |
| T16571 |
24044-24057 |
NN |
denotes |
glycosylation |
| T12246 |
24058-24063 |
NNS |
denotes |
sites |
| T58601 |
24064-24065 |
-LRB- |
denotes |
( |
| T48372 |
24065-24067 |
NN |
denotes |
SI |
| T90304 |
24068-24074 |
NN |
denotes |
Fig. 8 |
| T71179 |
24074-24075 |
-RRB- |
denotes |
) |
| T66481 |
24077-24085 |
IN |
denotes |
Although |
| T38463 |
24086-24088 |
PRP |
denotes |
it |
| T32700 |
24089-24091 |
VBZ |
denotes |
is |
| T80633 |
24092-24101 |
JJ |
denotes |
difficult |
| T73791 |
24102-24104 |
TO |
denotes |
to |
| T38418 |
24105-24113 |
RB |
denotes |
directly |
| T73114 |
24114-24121 |
VB |
denotes |
compare |
| T86863 |
24122-24129 |
NNS |
denotes |
viruses |
| T8410 |
24130-24132 |
IN |
denotes |
in |
| T65868 |
24133-24138 |
NNS |
denotes |
terms |
| T23843 |
24139-24141 |
IN |
denotes |
of |
| T28466 |
24142-24153 |
JJ |
denotes |
immunogenic |
| T17810 |
24154-24163 |
NNS |
denotes |
responses |
| T36441 |
24163-24164 |
-COMMA- |
denotes |
, |
| T29228 |
24165-24167 |
IN |
denotes |
on |
| T30037 |
24168-24171 |
DT |
denotes |
the |
| T26015 |
24172-24175 |
CD |
denotes |
one |
| T67621 |
24176-24180 |
NN |
denotes |
hand |
| T57010 |
24180-24181 |
-COMMA- |
denotes |
, |
| T90266 |
24182-24186 |
NN |
denotes |
SARS |
| T24380 |
24187-24190 |
CC |
denotes |
and |
| T36665 |
24191-24195 |
NN |
denotes |
MERS |
| T44450 |
24196-24209 |
NNS |
denotes |
coronaviruses |
| T66786 |
24210-24217 |
RB |
denotes |
readily |
| T32211 |
24218-24224 |
VBP |
denotes |
elicit |
| T72375 |
24225-24237 |
VBG |
denotes |
neutralizing |
| T20910 |
24238-24248 |
NNS |
denotes |
antibodies |
| T2480 |
24249-24258 |
VBG |
denotes |
following |
| T94939 |
24259-24268 |
NN |
denotes |
infection |
| T86648 |
24269-24271 |
CC |
denotes |
or |
| T76172 |
24272-24289 |
NN |
denotes |
immunization62–65 |
| T55600 |
24291-24297 |
RB |
denotes |
Indeed |
| T32116 |
24297-24298 |
-COMMA- |
denotes |
, |
| T76597 |
24299-24303 |
JJ |
denotes |
many |
| T32770 |
24304-24313 |
JJ |
denotes |
potential |
| T12004 |
24314-24322 |
NN |
denotes |
MERS-CoV |
| T73974 |
24323-24330 |
NN |
denotes |
vaccine |
| T17681 |
24331-24341 |
NNS |
denotes |
candidates |
| T49759 |
24342-24345 |
VBP |
denotes |
are |
| T53332 |
24346-24350 |
JJ |
denotes |
able |
| T55323 |
24351-24353 |
TO |
denotes |
to |
| T15804 |
24354-24360 |
VB |
denotes |
elicit |
| T39172 |
24361-24365 |
JJ |
denotes |
high |
| T65162 |
24366-24372 |
NNS |
denotes |
titres |
| T41593 |
24373-24375 |
IN |
denotes |
of |
| T16400 |
24376-24381 |
NN |
denotes |
serum |
| T48129 |
24382-24385 |
NN |
denotes |
IgG |
| T52826 |
24386-24390 |
IN |
denotes |
upon |
| T87524 |
24391-24403 |
NN |
denotes |
immunization |
| T13436 |
24404-24407 |
CC |
denotes |
but |
| T79396 |
24408-24412 |
VBP |
denotes |
fail |
| T3099 |
24413-24415 |
TO |
denotes |
to |
| T40686 |
24416-24423 |
VB |
denotes |
produce |
| T65430 |
24424-24434 |
JJ |
denotes |
sufficient |
| T95434 |
24435-24442 |
JJ |
denotes |
mucosal |
| T85744 |
24443-24453 |
NN |
denotes |
immunity65 |
| T60855 |
24455-24457 |
IN |
denotes |
In |
| T15145 |
24458-24466 |
NN |
denotes |
contrast |
| T83757 |
24466-24467 |
-COMMA- |
denotes |
, |
| T41451 |
24468-24471 |
DT |
denotes |
the |
| T95094 |
24472-24476 |
JJ |
denotes |
high |
| T76290 |
24477-24485 |
NN |
denotes |
mutation |
| T92271 |
24486-24492 |
NN |
denotes |
rate66 |
| T59290 |
24493-24496 |
CC |
denotes |
and |
| T46337 |
24497-24500 |
DT |
denotes |
the |
| T52476 |
24501-24509 |
VBG |
denotes |
evolving |
| T10675 |
24510-24516 |
NN |
denotes |
glycan |
| T18714 |
24517-24523 |
NN |
denotes |
shield |
| T37792 |
24524-24526 |
IN |
denotes |
of |
| T21845 |
24527-24537 |
NN |
denotes |
HIV-120,39 |
| T87196 |
24537-24538 |
-COMMA- |
denotes |
, |
| T16269 |
24539-24544 |
WDT |
denotes |
which |
| T23317 |
24545-24551 |
RB |
denotes |
firmly |
| T90485 |
24552-24563 |
VBZ |
denotes |
exemplifies |
| T49535 |
24564-24566 |
PRP |
denotes |
it |
| T16896 |
24567-24569 |
IN |
denotes |
as |
| T63209 |
24570-24578 |
NN |
denotes |
“evasion |
| T42025 |
24579-24586 |
NN |
denotes |
strong” |
| T63465 |
24587-24592 |
NN |
denotes |
virus |
| T4468 |
24592-24593 |
-COMMA- |
denotes |
, |
| T1830 |
24594-24601 |
VBZ |
denotes |
hinders |
| T56636 |
24602-24605 |
DT |
denotes |
the |
| T80263 |
24606-24617 |
NN |
denotes |
development |
| T21297 |
24618-24620 |
IN |
denotes |
of |
| T77941 |
24621-24628 |
RB |
denotes |
broadly |
| T47145 |
24629-24641 |
VBG |
denotes |
neutralizing |
| T48978 |
24642-24662 |
NNS |
denotes |
antibodies67.Viruses |
| T78349 |
24663-24673 |
VBN |
denotes |
classified |
| T84508 |
24674-24676 |
IN |
denotes |
as |
| T99687 |
24677-24685 |
NN |
denotes |
“evasion |
| T94485 |
24686-24698 |
NN |
denotes |
strong”26,56 |
| T8371 |
24699-24702 |
MD |
denotes |
may |
| T70765 |
24703-24707 |
RB |
denotes |
then |
| T19557 |
24708-24714 |
VB |
denotes |
differ |
| T68211 |
24715-24718 |
JJ |
denotes |
due |
| T58964 |
24719-24721 |
TO |
denotes |
to |
| T91845 |
24722-24728 |
JJ |
denotes |
varied |
| T28724 |
24729-24739 |
NNS |
denotes |
efficacies |
| T35775 |
24740-24742 |
IN |
denotes |
of |
| T42494 |
24743-24750 |
NN |
denotes |
protein |
| T48391 |
24751-24758 |
NN |
denotes |
surface |
| T91764 |
24759-24768 |
NN |
denotes |
shielding |
| T1369 |
24769-24771 |
IN |
denotes |
by |
| T1370 |
24772-24779 |
NNS |
denotes |
glycans |
| T1371 |
24781-24788 |
RB |
denotes |
Overall |
| T1372 |
24788-24789 |
-COMMA- |
denotes |
, |
| T1373 |
24790-24794 |
DT |
denotes |
this |
| T1374 |
24795-24800 |
NN |
denotes |
study |
| T1375 |
24801-24805 |
VBZ |
denotes |
adds |
| T1376 |
24806-24813 |
JJ |
denotes |
further |
| T1377 |
24814-24822 |
NN |
denotes |
evidence |
| T1378 |
24823-24833 |
VBG |
denotes |
suggesting |
| T1379 |
24834-24838 |
IN |
denotes |
that |
| T1380 |
24839-24848 |
JJ |
denotes |
extensive |
| T1381 |
24849-24857 |
JJ |
denotes |
N-linked |
| T1382 |
24858-24864 |
NN |
denotes |
glycan |
| T1383 |
24865-24878 |
NNS |
denotes |
modifications |
| T1384 |
24879-24881 |
IN |
denotes |
of |
| T47921 |
24882-24886 |
NNP |
denotes |
SARS |
| T1386 |
24887-24890 |
CC |
denotes |
and |
| T1387 |
24891-24895 |
NNP |
denotes |
MERS |
| T1388 |
24896-24899 |
NN |
denotes |
CoV |
| T1389 |
24900-24901 |
NN |
denotes |
S |
| T1390 |
24902-24910 |
NNS |
denotes |
proteins |
| T1391 |
24911-24913 |
VBP |
denotes |
do |
| T1392 |
24914-24917 |
RB |
denotes |
not |
| T1393 |
24918-24928 |
VB |
denotes |
constitute |
| T1394 |
24929-24931 |
DT |
denotes |
an |
| T1395 |
24932-24941 |
JJ |
denotes |
effective |
| T1396 |
24942-24948 |
NN |
denotes |
shield |
| T1397 |
24948-24949 |
-COMMA- |
denotes |
, |
| T1398 |
24950-24952 |
IN |
denotes |
in |
| T1399 |
24953-24963 |
NN |
denotes |
comparison |
| T1400 |
24964-24966 |
TO |
denotes |
to |
| T1401 |
24967-24973 |
NN |
denotes |
glycan |
| T1402 |
24974-24981 |
NNS |
denotes |
shields |
| T1403 |
24982-24984 |
IN |
denotes |
of |
| T1404 |
24985-24992 |
JJ |
denotes |
certain |
| T1405 |
24993-24998 |
JJ |
denotes |
other |
| T1406 |
24999-25006 |
NNS |
denotes |
viruses |
| T1407 |
25006-25007 |
-COMMA- |
denotes |
, |
| T1408 |
25008-25013 |
WDT |
denotes |
which |
| T1409 |
25014-25016 |
VBZ |
denotes |
is |
| T1410 |
25017-25026 |
VBN |
denotes |
reflected |
| T1411 |
25027-25029 |
IN |
denotes |
by |
| T1412 |
25030-25033 |
DT |
denotes |
the |
| T1413 |
25034-25041 |
JJ |
denotes |
overall |
| T1414 |
25042-25051 |
NN |
denotes |
structure |
| T1415 |
25051-25052 |
-COMMA- |
denotes |
, |
| T1416 |
25053-25060 |
NN |
denotes |
density |
| T1417 |
25061-25064 |
CC |
denotes |
and |
| T1418 |
25065-25077 |
NN |
denotes |
oligomannose |
| T1419 |
25078-25087 |
NN |
denotes |
abundance |
| T1420 |
25088-25094 |
IN |
denotes |
across |
| T1421 |
25095-25098 |
DT |
denotes |
the |
| T1422 |
25099-25112 |
VBG |
denotes |
corresponding |
| T1423 |
25113-25121 |
JJ |
denotes |
trimeric |
| T1424 |
25122-25135 |
NNS |
denotes |
glycoproteins |
| T1425 |
25137-25139 |
PRP |
denotes |
We |
| T1426 |
25140-25144 |
RB |
denotes |
also |
| T1427 |
25145-25156 |
VBP |
denotes |
demonstrate |
| T1428 |
25157-25161 |
IN |
denotes |
that |
| T1429 |
25162-25172 |
JJ |
denotes |
amino-acid |
| T1430 |
25173-25188 |
NN |
denotes |
diversification |
| T1431 |
25189-25195 |
RB |
denotes |
indeed |
| T1432 |
25196-25202 |
VBZ |
denotes |
occurs |
| T1433 |
25203-25205 |
IN |
denotes |
at |
| T1434 |
25206-25214 |
NN |
denotes |
antibody |
| T1435 |
25215-25225 |
JJ |
denotes |
accessible |
| T1436 |
25226-25233 |
NNS |
denotes |
regions |
| T1437 |
25234-25236 |
IN |
denotes |
on |
| T1438 |
25237-25240 |
DT |
denotes |
the |
| T1439 |
25241-25247 |
NN |
denotes |
trimer |
| T1440 |
25247-25248 |
-COMMA- |
denotes |
, |
| T1441 |
25249-25254 |
WDT |
denotes |
which |
| T1442 |
25255-25263 |
VBZ |
denotes |
confirms |
| T1443 |
25264-25268 |
IN |
denotes |
that |
| T1444 |
25269-25276 |
NNS |
denotes |
glycans |
| T1445 |
25277-25281 |
VBP |
denotes |
play |
| T1446 |
25282-25283 |
DT |
denotes |
a |
| T1447 |
25284-25288 |
NN |
denotes |
role |
| T1448 |
25289-25291 |
IN |
denotes |
in |
| T1449 |
25292-25301 |
VBG |
denotes |
occluding |
| T1450 |
25302-25310 |
JJ |
denotes |
specific |
| T1451 |
25311-25318 |
NNS |
denotes |
regions |
| T1452 |
25319-25321 |
IN |
denotes |
if |
| T1453 |
25322-25335 |
NN |
denotes |
vulnerability |
| T1454 |
25336-25338 |
IN |
denotes |
on |
| T1455 |
25339-25342 |
DT |
denotes |
the |
| T1456 |
25343-25355 |
NN |
denotes |
glycoprotein |
| T1457 |
25357-25368 |
RB |
denotes |
Furthermore |
| T1458 |
25368-25369 |
-COMMA- |
denotes |
, |
| T1459 |
25370-25381 |
NNS |
denotes |
comparisons |
| T1460 |
25382-25389 |
IN |
denotes |
between |
| T1461 |
25390-25396 |
NN |
denotes |
glycan |
| T1462 |
25397-25404 |
NNS |
denotes |
shields |
| T1463 |
25405-25409 |
IN |
denotes |
from |
| T1464 |
25410-25411 |
DT |
denotes |
a |
| T1465 |
25412-25418 |
NN |
denotes |
number |
| T1466 |
25419-25421 |
IN |
denotes |
of |
| T1467 |
25422-25429 |
NNS |
denotes |
viruses |
| T1468 |
25430-25439 |
VBP |
denotes |
highlight |
| T1469 |
25440-25443 |
DT |
denotes |
the |
| T1470 |
25444-25454 |
NN |
denotes |
importance |
| T1471 |
25455-25457 |
IN |
denotes |
of |
| T1472 |
25458-25459 |
DT |
denotes |
a |
| T1473 |
25460-25466 |
NN |
denotes |
glycan |
| T1474 |
25467-25473 |
NN |
denotes |
shield |
| T1475 |
25474-25476 |
IN |
denotes |
in |
| T1476 |
25477-25483 |
JJ |
denotes |
immune |
| T1477 |
25484-25491 |
NN |
denotes |
evasion |
| T1478 |
25492-25495 |
CC |
denotes |
and |
| T1479 |
25496-25502 |
VBP |
denotes |
reveal |
| T1480 |
25503-25513 |
JJ |
denotes |
structural |
| T1481 |
25514-25524 |
NNS |
denotes |
principles |
| T1482 |
25525-25529 |
WDT |
denotes |
that |
| T1483 |
25530-25536 |
VBP |
denotes |
govern |
| T1484 |
25537-25550 |
NN |
denotes |
glycosylation |
| T1485 |
25551-25557 |
NN |
denotes |
status |
| T1486 |
25560-25567 |
NNS |
denotes |
Methods |
| T1487 |
25569-25579 |
NN |
denotes |
Expression |
| T1488 |
25580-25583 |
CC |
denotes |
and |
| T1489 |
25584-25596 |
NN |
denotes |
purification |
| T1490 |
25597-25599 |
IN |
denotes |
of |
| T1491 |
25600-25611 |
NN |
denotes |
coronavirus |
| T1492 |
25612-25617 |
NN |
denotes |
spike |
| T1493 |
25618-25631 |
NNS |
denotes |
glycoproteins |
| R1000 |
T995 |
T994 |
arg1Of |
proteins,S |
| R10009 |
T96165 |
T61859 |
arg1Of |
residues,of |
| R1001 |
T1001 |
T996 |
arg1Of |
note,It |
| R1002 |
T1001 |
T997 |
arg1Of |
note,is |
| R1003 |
T999 |
T997 |
arg2Of |
interesting,is |
| R1004 |
T997 |
T998 |
arg1Of |
is,also |
| R1005 |
T1001 |
T999 |
arg1Of |
note,interesting |
| R10051 |
T8494 |
T33083 |
arg3Of |
),( |
| R1006 |
T1001 |
T1000 |
arg1Of |
note,to |
| R10069 |
T44453 |
T12305 |
arg1Of |
densities,and |
| R1007 |
T1008 |
T1001 |
arg2Of |
was,note |
| R10078 |
T39465 |
T2313 |
arg1Of |
“shields”,glycan |
| R1008 |
T1008 |
T1002 |
arg1Of |
was,that |
| R1009 |
T1004 |
T1003 |
arg1Of |
distribution,the |
| R1010 |
T1004 |
T1005 |
arg1Of |
distribution,of |
| R1011 |
T1007 |
T1005 |
arg2Of |
glycans,of |
| R1012 |
T1007 |
T1006 |
arg1Of |
glycans,oligomannose-type |
| R1013 |
T1004 |
T1008 |
arg1Of |
distribution,was |
| R1014 |
T1009 |
T1008 |
arg2Of |
broad,was |
| R1015 |
T1004 |
T1009 |
arg1Of |
distribution,broad |
| R10158 |
T31427 |
T9774 |
arg1Of |
proteins,recombinant |
| R1016 |
T1017 |
T1009 |
arg2Of |
present,broad |
| R1017 |
T1009 |
T1010 |
arg1Of |
broad,"," |
| R1018 |
T1009 |
T1011 |
arg1Of |
broad,with |
| R1019 |
T1012 |
T1011 |
arg2Of |
Man5GlcNAc2,with |
| R10199 |
T42372 |
T61083 |
arg2Of |
S,and |
| R1020 |
T1014 |
T1013 |
arg1Of |
Man9GlcNAc2,to |
| R1021 |
T1015 |
T1014 |
arg2Of |
glycans,Man9GlcNAc2 |
| R1022 |
T1017 |
T1016 |
arg1Of |
present,all |
| R1023 |
T1014 |
T1017 |
arg1Of |
Man9GlcNAc2,present |
| R1024 |
T1017 |
T1018 |
arg1Of |
present,"," |
| R1025 |
T1017 |
T1019 |
arg1Of |
present,without |
| R1026 |
T1023 |
T1019 |
arg2Of |
peak,without |
| R1027 |
T1023 |
T1020 |
arg1Of |
peak,one |
| R10275 |
T25653 |
T71306 |
arg1Of |
SARS-CoV-2,the |
| R1028 |
T1023 |
T1021 |
arg1Of |
peak,particular |
| R10287 |
T76130 |
T34257 |
arg1Of |
site,the |
| R1029 |
T1023 |
T1022 |
arg1Of |
peak,dominant |
| R1030 |
T1017 |
T1024 |
arg1Of |
present,"," |
| R1031 |
T1017 |
T1025 |
arg1Of |
present,as |
| R1032 |
T1026 |
T1025 |
arg2Of |
is,as |
| R1033 |
T1028 |
T1026 |
arg1Of |
case,is |
| R1034 |
T1028 |
T1027 |
arg1Of |
case,the |
| R10349 |
T91445 |
T32785 |
arg1Of |
This,revealed |
| R1035 |
T1028 |
T1029 |
arg1Of |
case,for |
| R1036 |
T1032 |
T1029 |
arg2Of |
glycoproteins,for |
| R10360 |
T80082 |
T50688 |
arg2Of |
glycopeptides,yield |
| R10363 |
T84409 |
T7737 |
arg1Of |
site-specific,digested. Quantitative |
| R1037 |
T1032 |
T1030 |
arg1Of |
glycoproteins,some |
| R10375 |
T16458 |
T21233 |
arg1Of |
dataset52,published |
| R1038 |
T1032 |
T1031 |
arg1Of |
glycoproteins,viral |
| R1039 |
T1032 |
T1033 |
arg1Of |
glycoproteins,"," |
| R1040 |
T1035 |
T1034 |
arg1Of |
as,such |
| R10402 |
T65839 |
T58427 |
arg2Of |
and,to |
| R1041 |
T1032 |
T1035 |
arg1Of |
glycoproteins,as |
| R10411 |
T32200 |
T83554 |
arg1Of |
antibodies,"," |
| R1042 |
T1037 |
T1035 |
arg2Of |
Env36,as |
| R1043 |
T1037 |
T1036 |
arg1Of |
Env36,HIV-1 |
| R1044 |
T1039 |
T1038 |
arg1Of |
proportion,The |
| R1045 |
T1039 |
T1040 |
arg1Of |
proportion,of |
| R1046 |
T1042 |
T1040 |
arg2Of |
glycans,of |
| R10463 |
T77822 |
T22651 |
arg1Of |
"glycoprotein22,58",the |
| R1047 |
T1042 |
T1041 |
arg1Of |
glycans,oligomannose-type |
| R1048 |
T1039 |
T1043 |
arg1Of |
proportion,on |
| R10483 |
T58379 |
T74716 |
arg2Of |
target,is |
| R1049 |
T1047 |
T1043 |
arg2Of |
proteins,on |
| R1050 |
T1047 |
T1044 |
arg1Of |
proteins,recombinant |
| R1051 |
T1047 |
T1045 |
arg1Of |
proteins,coronavirus |
| R10516 |
T86793 |
T76095 |
arg1Of |
epitopes,"," |
| R1052 |
T1047 |
T1046 |
arg1Of |
proteins,S |
| R10524 |
T79807 |
T84889 |
arg1Of |
Fig. 3a,"," |
| R1053 |
T1039 |
T1048 |
arg1Of |
proportion,is |
| R10534 |
T95495 |
T2559 |
arg1Of |
grey,grey |
| R1054 |
T1049 |
T1048 |
arg2Of |
consistent,is |
| R1055 |
T1039 |
T1049 |
arg1Of |
proportion,consistent |
| R1056 |
T1049 |
T1050 |
arg1Of |
consistent,with |
| R1057 |
T1052 |
T1050 |
arg2Of |
studies,with |
| R1058 |
T1052 |
T1051 |
arg1Of |
studies,previous |
| R1059 |
T1052 |
T1053 |
arg2Of |
studies,performed |
| R1060 |
T1053 |
T1054 |
arg1Of |
performed,on |
| R1061 |
T1058 |
T1054 |
arg2Of |
and,on |
| R1062 |
T1056 |
T1055 |
arg1Of |
derived,virally |
| R1063 |
T1057 |
T1056 |
arg1Of |
MERS,derived |
| R10631 |
T71298 |
T50579 |
arg1Of |
glycoproteins,including |
| R1064 |
T1057 |
T1058 |
arg1Of |
MERS,and |
| R1065 |
T1062 |
T1058 |
arg2Of |
"proteins17,42",and |
| R1066 |
T1062 |
T1059 |
arg1Of |
"proteins17,42",SARS |
| R10660 |
T65942 |
T71992 |
arg1Of |
Fabs51,RM20A3 |
| R1067 |
T1062 |
T1060 |
arg1Of |
"proteins17,42",coronavirus |
| R10673 |
T19959 |
T23506 |
arg1Of |
remaining,still |
| R1068 |
T1062 |
T1061 |
arg1Of |
"proteins17,42",S |
| R1069 |
T1063 |
T1064 |
arg1Of |
Coronaviruses,have |
| R1070 |
T1068 |
T1064 |
arg2Of |
reported,have |
| R10702 |
T10989 |
T93688 |
arg1Of |
"response21,31",adaptive |
| R10709 |
T48593 |
T66189 |
arg1Of |
interactions,glycan–glycan |
| R1071 |
T1063 |
T1065 |
arg1Of |
Coronaviruses,been |
| R10719 |
T85689 |
T97136 |
arg1Of |
proportion,greater |
| R1072 |
T1068 |
T1065 |
arg2Of |
reported,been |
| R10724 |
T23904 |
T72733 |
arg2Of |
PNGs,replacing |
| R1073 |
T1068 |
T1066 |
arg1Of |
reported,previously |
| R1074 |
T1063 |
T1067 |
arg1Of |
Coronaviruses,been |
| R10741 |
T39562 |
T86316 |
arg1Of |
b,map51. |
| R1075 |
T1068 |
T1067 |
arg2Of |
reported,been |
| R1076 |
T1063 |
T1068 |
arg2Of |
Coronaviruses,reported |
| R1077 |
T1070 |
T1068 |
arg3Of |
form,reported |
| R1078 |
T1070 |
T1069 |
arg1Of |
form,to |
| R10787 |
T40354 |
T8442 |
arg1Of |
found,on |
| R1079 |
T1063 |
T1070 |
arg1Of |
Coronaviruses,form |
| R10796 |
T73292 |
T25939 |
arg1Of |
analysis,revealed |
| R1080 |
T1071 |
T1070 |
arg2Of |
virions,form |
| R10800 |
T24412 |
T16685 |
arg2Of |
limit,is |
| R1081 |
T1070 |
T1072 |
arg1Of |
form,by |
| R1082 |
T1073 |
T1072 |
arg2Of |
budding,by |
| R1083 |
T1063 |
T1073 |
arg1Of |
Coronaviruses,budding |
| R1084 |
T1073 |
T1074 |
arg1Of |
budding,into |
| R1085 |
T1076 |
T1074 |
arg2Of |
lumen,into |
| R1086 |
T1076 |
T1075 |
arg1Of |
lumen,the |
| R1087 |
T1076 |
T1077 |
arg1Of |
lumen,of |
| R1088 |
T1081 |
T1077 |
arg2Of |
compartments,of |
| R1089 |
T1081 |
T1078 |
arg1Of |
compartments,endoplasmic |
| R10896 |
T84155 |
T94649 |
arg1Of |
functions,its |
| R1090 |
T1081 |
T1079 |
arg1Of |
compartments,reticulum-Golgi |
| R1091 |
T1081 |
T1080 |
arg1Of |
compartments,intermediate |
| R1092 |
T1081 |
T1082 |
arg1Of |
compartments,( |
| R1093 |
T1083 |
T1082 |
arg2Of |
ERGIC,( |
| R1094 |
T1084 |
T1082 |
arg3Of |
),( |
| R10946 |
T3262 |
T93400 |
arg1Of |
glycoproteins,N-linked |
| R1095 |
T1081 |
T1085 |
arg1Of |
compartments,"43,44" |
| R1096 |
T1086 |
T1087 |
arg1Of |
Observations,of |
| R1097 |
T1089 |
T1087 |
arg2Of |
and,of |
| R1098 |
T1088 |
T1089 |
arg1Of |
hybrid-,and |
| R10980 |
T36665 |
T24380 |
arg2Of |
MERS,and |
| R10984 |
T99216 |
T22467 |
arg2Of |
unknown,is |
| R10987 |
T18955 |
T13208 |
arg1Of |
Asn155,"," |
| R1099 |
T1091 |
T1089 |
arg2Of |
glycans,and |
| R1100 |
T1091 |
T1090 |
arg1Of |
glycans,complex-type |
| R1101 |
T1089 |
T1092 |
arg1Of |
and,on |
| R1102 |
T1095 |
T1092 |
arg2Of |
"material17,42",on |
| R11020 |
T74525 |
T72420 |
arg1Of |
but,Interestingly |
| R1103 |
T1094 |
T1093 |
arg1Of |
derived,virally |
| R1104 |
T1095 |
T1094 |
arg1Of |
"material17,42",derived |
| R1105 |
T1086 |
T1096 |
arg1Of |
Observations,would |
| R1106 |
T1100 |
T1099 |
arg2Of |
suggest,"," |
| R1107 |
T1086 |
T1100 |
arg1Of |
Observations,suggest |
| R1108 |
T1103 |
T1100 |
arg2Of |
is,suggest |
| R1109 |
T1103 |
T1101 |
arg1Of |
is,that |
| R11093 |
T10324 |
T18378 |
arg2Of |
ratios,( |
| R1110 |
T1102 |
T1103 |
arg1Of |
it,is |
| R1111 |
T1104 |
T1103 |
arg2Of |
likely,is |
| R11117 |
T58864 |
T16213 |
arg1Of |
diversity,amino-acid |
| R1112 |
T1102 |
T1104 |
arg1Of |
it,likely |
| R1113 |
T1108 |
T1104 |
arg2Of |
travel,likely |
| R1114 |
T1108 |
T1105 |
arg1Of |
travel,that |
| R11142 |
T31427 |
T12013 |
arg1Of |
proteins,HKU1 |
| R1115 |
T1107 |
T1106 |
arg1Of |
virions,coronavirus |
| R1116 |
T1107 |
T1108 |
arg1Of |
virions,travel |
| R1117 |
T1108 |
T1109 |
arg1Of |
travel,through |
| R1118 |
T1112 |
T1109 |
arg2Of |
apparatus,through |
| R11187 |
T15627 |
T39650 |
arg1Of |
nanobodies,( |
| R1119 |
T1112 |
T1110 |
arg1Of |
apparatus,the |
| R1120 |
T1112 |
T1111 |
arg1Of |
apparatus,Golgi |
| R1121 |
T1112 |
T1113 |
arg1Of |
apparatus,after |
| R1122 |
T1115 |
T1113 |
arg2Of |
formation,after |
| R1123 |
T1115 |
T1114 |
arg1Of |
formation,virion |
| R11238 |
T83973 |
T22042 |
arg2Of |
residues,buried |
| R1124 |
T1115 |
T1116 |
arg1Of |
formation,in |
| R1125 |
T1118 |
T1116 |
arg2Of |
ERGIC,in |
| R1126 |
T1118 |
T1117 |
arg1Of |
ERGIC,the |
| R1127 |
T1118 |
T1119 |
arg1Of |
ERGIC,en |
| R1128 |
T1120 |
T1119 |
arg2Of |
route,en |
| R1129 |
T1118 |
T1121 |
arg1Of |
ERGIC,to |
| R11295 |
T55170 |
T96574 |
arg1Of |
inhibition,protein-directed |
| R1130 |
T1124 |
T1121 |
arg2Of |
surface,to |
| R1131 |
T1124 |
T1122 |
arg1Of |
surface,the |
| R1132 |
T1124 |
T1123 |
arg1Of |
surface,cell |
| R1133 |
T1103 |
T1125 |
arg1Of |
is,"," |
| R1134 |
T1127 |
T1126 |
arg1Of |
supporting,thus |
| R1135 |
T1102 |
T1127 |
arg1Of |
it,supporting |
| R1136 |
T1129 |
T1127 |
arg2Of |
immunogens,supporting |
| R1137 |
T1103 |
T1127 |
modOf |
is,supporting |
| R1138 |
T1129 |
T1128 |
arg1Of |
immunogens,recombinant |
| R1139 |
T1127 |
T1130 |
arg1Of |
supporting,as |
| R1140 |
T1131 |
T1130 |
arg2Of |
models,as |
| R1141 |
T1131 |
T1132 |
arg1Of |
models,of |
| R1142 |
T1134 |
T1132 |
arg2Of |
glycoproteins,of |
| R1143 |
T1134 |
T1133 |
arg1Of |
glycoproteins,viral |
| R11432 |
T85948 |
T18466 |
arg1Of |
perturbing,greatly |
| R1144 |
T1138 |
T1135 |
arg1Of |
analysis,Fig. |
| R11447 |
T28741 |
T38149 |
arg2Of |
mapping,of |
| R1145 |
T1135 |
T1136 |
arg1Of |
Fig.,1 |
| R1146 |
T1138 |
T1137 |
arg1Of |
analysis,Compositional |
| R11468 |
T43288 |
T96310 |
arg2Of |
resides,exposed |
| R1147 |
T1138 |
T1139 |
arg1Of |
analysis,of |
| R1148 |
T1140 |
T1139 |
arg2Of |
SARS,of |
| R1149 |
T1140 |
T1141 |
arg1Of |
SARS,"," |
| R1150 |
T1143 |
T1141 |
arg2Of |
and,"," |
| R1151 |
T1142 |
T1143 |
arg1Of |
MERS,and |
| R11512 |
T21366 |
T99446 |
arg1Of |
sites,glycosylation |
| R1152 |
T1145 |
T1143 |
arg2Of |
glycans,and |
| R11527 |
T66745 |
T45284 |
arg1Of |
trimer,revealing |
| R1153 |
T1145 |
T1144 |
arg1Of |
glycans,HKU1 |
| R1154 |
T1148 |
T1146 |
arg1Of |
representation,a |
| R1155 |
T1148 |
T1147 |
arg1Of |
representation,Schematic |
| R11557 |
T39985 |
T22591 |
arg1Of |
incorporated,in |
| R1156 |
T1148 |
T1149 |
arg1Of |
representation,of |
| R11568 |
T86788 |
T67118 |
arg2Of |
PISA,( |
| R1157 |
T1153 |
T1149 |
arg2Of |
and,of |
| R11577 |
T59031 |
T94235 |
arg1Of |
glycans,on |
| R1158 |
T1150 |
T1151 |
arg1Of |
SARS,"," |
| R1159 |
T1152 |
T1151 |
arg2Of |
MERS,"," |
| R1160 |
T1151 |
T1153 |
arg1Of |
",",and |
| R11603 |
T97319 |
T70902 |
arg2Of |
role,plays |
| R1161 |
T1157 |
T1153 |
arg2Of |
glycoproteins,and |
| R1162 |
T1157 |
T1154 |
arg1Of |
glycoproteins,HKU1 |
| R1163 |
T1157 |
T1155 |
arg1Of |
glycoproteins,coronavirus |
| R1164 |
T1157 |
T1156 |
arg1Of |
glycoproteins,S |
| R1165 |
T1148 |
T1158 |
arg1Of |
representation,"," |
| R1166 |
T1148 |
T1159 |
arg1Of |
representation,showing |
| R1167 |
T1161 |
T1159 |
arg2Of |
positions,showing |
| R1168 |
T1161 |
T1160 |
arg1Of |
positions,the |
| R1169 |
T1161 |
T1162 |
arg1Of |
positions,of |
| R1170 |
T1166 |
T1162 |
arg2Of |
sequons,of |
| R1171 |
T1166 |
T1163 |
arg1Of |
sequons,N-linked |
| R11713 |
T36034 |
T40453 |
arg1Of |
epitopes,similar |
| R1172 |
T1166 |
T1164 |
arg1Of |
sequons,glycosylation |
| R1173 |
T1166 |
T1165 |
arg1Of |
sequons,amino-acid |
| R1174 |
T1166 |
T1167 |
arg1Of |
sequons,( |
| R1175 |
T1168 |
T1167 |
arg2Of |
NXS/T,( |
| R1176 |
T1172 |
T1167 |
arg3Of |
),( |
| R1177 |
T1168 |
T1169 |
arg1Of |
NXS/T,"," |
| R11772 |
T11314 |
T78469 |
arg1Of |
Env,HIV-1 |
| R1178 |
T1171 |
T1170 |
arg1Of |
X ≠ P,where |
| R11789 |
T31709 |
T15866 |
arg1Of |
structure,previously |
| R1179 |
T1168 |
T1171 |
arg1Of |
NXS/T,X ≠ P |
| R1180 |
T1166 |
T1173 |
arg2Of |
sequons,shown |
| R1181 |
T1173 |
T1174 |
arg1Of |
shown,as |
| R11819 |
T2354 |
T23968 |
arg1Of |
subunit,exhibits |
| R1182 |
T1175 |
T1174 |
arg2Of |
branches,as |
| R1183 |
T1178 |
T1177 |
arg1Of |
glycans,Oligomannose-type |
| R11834 |
T12931 |
T18889 |
arg1Of |
Env,HIV-1 |
| R1184 |
T1178 |
T1179 |
arg1Of |
glycans,are |
| R1185 |
T1181 |
T1179 |
arg2Of |
annotated,are |
| R1186 |
T1181 |
T1180 |
arg1Of |
annotated,schematically |
| R11867 |
T76353 |
T19094 |
arg2Of |
evolved,has |
| R1187 |
T1178 |
T1181 |
arg2Of |
glycans,annotated |
| R1188 |
T1181 |
T1182 |
arg1Of |
annotated,with |
| R11883 |
T17810 |
T28466 |
arg1Of |
responses,immunogenic |
| R1189 |
T1184 |
T1182 |
arg2Of |
residues,with |
| R1190 |
T1184 |
T1183 |
arg1Of |
residues,mannose |
| R11906 |
T36034 |
T34663 |
arg2Of |
epitopes,observed |
| R1191 |
T1181 |
T1185 |
arg1Of |
annotated,as |
| R1192 |
T1188 |
T1185 |
arg2Of |
and,as |
| R1193 |
T1187 |
T1186 |
arg1Of |
circles,green |
| R1194 |
T1187 |
T1188 |
arg1Of |
circles,and |
| R1195 |
T1190 |
T1188 |
arg2Of |
residues,and |
| R1196 |
T1190 |
T1189 |
arg1Of |
residues,GlcNAc |
| R1197 |
T1181 |
T1191 |
arg1Of |
annotated,as |
| R1198 |
T1193 |
T1191 |
arg2Of |
squares,as |
| R1199 |
T1193 |
T1192 |
arg1Of |
squares,blue |
| R1200 |
T1195 |
T1194 |
arg1Of |
ascertain,To |
| R1201 |
T1211 |
T1194 |
modOf |
analysed,To |
| R12013 |
T67339 |
T1758 |
arg1Of |
classified,as |
| R1202 |
T1198 |
T1195 |
arg2Of |
structures,ascertain |
| R1203 |
T1198 |
T1196 |
arg1Of |
structures,the |
| R1204 |
T1198 |
T1197 |
arg1Of |
structures,precise |
| R1205 |
T1198 |
T1199 |
arg1Of |
structures,of |
| R1206 |
T1201 |
T1199 |
arg2Of |
glycans,of |
| R12065 |
T66354 |
T93664 |
arg1Of |
shielding,restricted |
| R1207 |
T1201 |
T1200 |
arg1Of |
glycans,N-linked |
| R1208 |
T1211 |
T1202 |
arg1Of |
analysed,"," |
| R1209 |
T1204 |
T1203 |
arg1Of |
pools,glycan |
| R1210 |
T1204 |
T1205 |
arg1Of |
pools,of |
| R12104 |
T25939 |
T88293 |
arg1Of |
revealed,when |
| R1211 |
T1209 |
T1205 |
arg2Of |
protein,of |
| R1212 |
T1209 |
T1206 |
arg1Of |
protein,each |
| R12128 |
T74143 |
T41564 |
arg1Of |
density,of |
| R1213 |
T1209 |
T1207 |
arg1Of |
protein,coronavirus |
| R1214 |
T1209 |
T1208 |
arg1Of |
protein,S |
| R1215 |
T1204 |
T1210 |
arg1Of |
pools,were |
| R12152 |
T81512 |
T95497 |
arg1Of |
18,in |
| R1216 |
T1211 |
T1210 |
arg2Of |
analysed,were |
| R12169 |
T10378 |
T46370 |
arg1Of |
recognise,as |
| R1217 |
T1217 |
T1211 |
arg1Of |
spectrometry,analysed |
| R1218 |
T1204 |
T1211 |
arg2Of |
pools,analysed |
| R12180 |
T43119 |
T79243 |
arg1Of |
SARS,and |
| R1219 |
T1217 |
T1212 |
arg2Of |
spectrometry,by |
| R1220 |
T1217 |
T1213 |
arg1Of |
spectrometry,negative-ion |
| R12204 |
T50082 |
T38160 |
arg2Of |
S,"," |
| R1221 |
T1217 |
T1214 |
arg1Of |
spectrometry,ion-mobility-electrospray |
| R1222 |
T1217 |
T1215 |
arg1Of |
spectrometry,ionisation |
| R1223 |
T1217 |
T1216 |
arg1Of |
spectrometry,mass |
| R1224 |
T1217 |
T1218 |
arg1Of |
spectrometry,( |
| R1225 |
T1220 |
T1218 |
arg2Of |
MS,( |
| R1226 |
T1221 |
T1218 |
arg3Of |
),( |
| R1227 |
T1220 |
T1219 |
arg1Of |
MS,IM-ESI |
| R1228 |
T1217 |
T1222 |
arg1Of |
spectrometry,( |
| R12287 |
T20304 |
T68204 |
arg3Of |
differences,measured |
| R1229 |
T1224 |
T1222 |
arg2Of |
Fig. 1,( |
| R1230 |
T1225 |
T1222 |
arg3Of |
),( |
| R1231 |
T1224 |
T1223 |
arg1Of |
Fig. 1,Supplementary |
| R1232 |
T1234 |
T1226 |
arg1Of |
confirmed,Consistent |
| R1233 |
T1226 |
T1227 |
arg1Of |
Consistent,with |
| R1234 |
T1230 |
T1227 |
arg2Of |
data,with |
| R1235 |
T1230 |
T1228 |
arg1Of |
data,the |
| R1236 |
T1230 |
T1229 |
arg1Of |
data,UPLC |
| R12367 |
T54008 |
T35302 |
arg1Of |
diversity,was |
| R1237 |
T1234 |
T1231 |
arg1Of |
confirmed,"," |
| R1238 |
T1233 |
T1232 |
arg1Of |
MS,IM-ESI |
| R1239 |
T1233 |
T1234 |
arg1Of |
MS,confirmed |
| R1240 |
T1236 |
T1234 |
arg2Of |
array,confirmed |
| R1241 |
T1236 |
T1235 |
arg1Of |
array,an |
| R1242 |
T1236 |
T1237 |
arg1Of |
array,of |
| R12423 |
T59031 |
T66013 |
arg1Of |
glycans,appear |
| R12427 |
T85689 |
T37643 |
arg1Of |
proportion,of |
| R12429 |
T65828 |
T55016 |
arg2Of |
residues,with |
| R1243 |
T1239 |
T1237 |
arg2Of |
glycans,of |
| R1244 |
T1239 |
T1238 |
arg1Of |
glycans,complex-type |
| R1245 |
T1239 |
T1240 |
arg1Of |
glycans,ranging |
| R1246 |
T1240 |
T1241 |
arg1Of |
ranging,from |
| R1247 |
T1242 |
T1241 |
arg2Of |
mono-,from |
| R12478 |
T71022 |
T86979 |
arg1Of |
S,SARS |
| R1248 |
T1242 |
T1243 |
arg1Of |
mono-,to |
| R1249 |
T1246 |
T1243 |
arg2Of |
but,to |
| R12493 |
T52754 |
T85424 |
arg1Of |
MERS,trimeric |
| R12499 |
T75554 |
T9896 |
arg2Of |
spikes,on |
| R1250 |
T1246 |
T1245 |
arg1Of |
but,"," |
| R12507 |
T25884 |
T85913 |
arg1Of |
values,are |
| R1251 |
T1244 |
T1246 |
arg1Of |
tetra-antennary,but |
| R1252 |
T1249 |
T1246 |
arg2Of |
and,but |
| R1253 |
T1246 |
T1247 |
arg1Of |
but,also |
| R1254 |
T1248 |
T1249 |
arg1Of |
oligomannose-,and |
| R1255 |
T1251 |
T1249 |
arg2Of |
glycans,and |
| R12558 |
T8069 |
T4310 |
arg1Of |
glycan28,substrate |
| R1256 |
T1251 |
T1250 |
arg1Of |
glycans,hybrid-type |
| R1257 |
T1254 |
T1252 |
arg1Of |
compositions,The |
| R12577 |
T66354 |
T45320 |
arg1Of |
shielding,glycan |
| R1258 |
T1254 |
T1253 |
arg1Of |
compositions,glycan |
| R1259 |
T1254 |
T1255 |
arg2Of |
compositions,characterised |
| R12595 |
T28784 |
T70607 |
arg1Of |
5X59,ID |
| R1260 |
T1255 |
T1256 |
arg1Of |
characterised,in |
| R1261 |
T1258 |
T1256 |
arg2Of |
spectra,in |
| R1262 |
T1258 |
T1257 |
arg1Of |
spectra,the |
| R12623 |
T82162 |
T92297 |
arg1Of |
as,such |
| R1263 |
T1254 |
T1259 |
arg1Of |
compositions,were |
| R1264 |
T1261 |
T1259 |
arg2Of |
invariant,were |
| R1265 |
T1261 |
T1260 |
arg1Of |
invariant,largely |
| R1266 |
T1254 |
T1261 |
arg1Of |
compositions,invariant |
| R12669 |
T39921 |
T46370 |
arg2Of |
patterns,as |
| R1267 |
T1261 |
T1262 |
arg1Of |
invariant,among |
| R12670 |
T39503 |
T73192 |
arg1Of |
this,result |
| R1268 |
T1264 |
T1262 |
arg2Of |
coronaviruses,among |
| R12683 |
T55061 |
T2491 |
arg1Of |
cells,Madin-Darby |
| R1269 |
T1264 |
T1263 |
arg1Of |
coronaviruses,the |
| R1270 |
T1264 |
T1265 |
arg1Of |
coronaviruses,with |
| R1271 |
T1269 |
T1265 |
arg2Of |
differences,with |
| R1272 |
T1269 |
T1266 |
arg1Of |
differences,no |
| R1273 |
T1269 |
T1267 |
arg1Of |
differences,major |
| R1274 |
T1269 |
T1268 |
arg1Of |
differences,structural |
| R1275 |
T1269 |
T1270 |
arg2Of |
differences,observed |
| R1276 |
T1271 |
T1272 |
arg1Of |
Clustering,of |
| R1277 |
T1274 |
T1272 |
arg2Of |
glycans,of |
| R1278 |
T1274 |
T1273 |
arg1Of |
glycans,underprocessed |
| R12788 |
T97859 |
T93687 |
arg2Of |
Structures,"," |
| R1279 |
T1271 |
T1275 |
arg1Of |
Clustering,on |
| R1280 |
T1277 |
T1275 |
arg2Of |
S,on |
| R1281 |
T1277 |
T1276 |
arg1Of |
S,MERS |
| R1282 |
T25019 |
T14782 |
arg2Of |
camels,from |
| R1283 |
T25019 |
T86652 |
arg1Of |
camels,into |
| R1284 |
T1639 |
T86652 |
arg2Of |
humans,into |
| R12844 |
T18459 |
T55071 |
arg1Of |
This,revealed |
| R1285 |
T1639 |
T23535 |
arg1Of |
humans,"," |
| R1286 |
T1639 |
T51241 |
arg1Of |
humans,where |
| R12860 |
T24662 |
T14862 |
arg1Of |
GPC,LASV |
| R1287 |
T59854 |
T51241 |
arg2Of |
circulated,where |
| R1288 |
T67194 |
T59854 |
arg1Of |
it,circulated |
| R1289 |
T59854 |
T82528 |
arg1Of |
circulated,transiently |
| R1290 |
T1281 |
T23126 |
arg1Of |
corresponded,In |
| R1291 |
T4625 |
T23126 |
arg2Of |
contrast,In |
| R12914 |
T15993 |
T99830 |
arg1Of |
presence,hindered |
| R1292 |
T1281 |
T47309 |
arg1Of |
corresponded,"," |
| R1293 |
T1280 |
T1278 |
arg1Of |
outbreak,the |
| R1294 |
T1280 |
T1279 |
arg1Of |
outbreak,SARS |
| R1295 |
T1280 |
T1281 |
arg1Of |
outbreak,corresponded |
| R12958 |
T7069 |
T2785 |
arg1Of |
correspond,while |
| R1296 |
T1281 |
T1282 |
arg1Of |
corresponded,to |
| R1297 |
T1286 |
T1282 |
arg2Of |
event,to |
| R1298 |
T1286 |
T1283 |
arg1Of |
event,a |
| R1299 |
T1286 |
T1284 |
arg1Of |
event,single |
| R1300 |
T1286 |
T1285 |
arg1Of |
event,zoonotic |
| R13007 |
T81517 |
T14224 |
arg2Of |
SIVcpz,( |
| R1301 |
T1291 |
T1287 |
arg1Of |
transmission,followed |
| R1302 |
T1286 |
T1287 |
arg2Of |
event,followed |
| R1303 |
T1291 |
T1288 |
arg2Of |
transmission,by |
| R13031 |
T2204 |
T67682 |
arg1Of |
sites,potential |
| R1304 |
T1291 |
T1289 |
arg1Of |
transmission,extensive |
| R1305 |
T1291 |
T1290 |
arg1Of |
transmission,human-to-human |
| R1306 |
T1307 |
T1292 |
arg1Of |
is,Consequently |
| R1307 |
T1307 |
T1293 |
arg1Of |
is,"," |
| R1308 |
T1296 |
T1294 |
arg2Of |
degree,inferring |
| R1309 |
T1296 |
T1295 |
arg1Of |
degree,the |
| R1310 |
T1296 |
T1297 |
arg1Of |
degree,of |
| R1311 |
T1298 |
T1297 |
arg2Of |
selection,of |
| R1312 |
T1296 |
T1299 |
arg1Of |
degree,acting |
| R13123 |
T60433 |
T21150 |
arg1Of |
calculated,by |
| R1313 |
T1299 |
T1300 |
arg1Of |
acting,upon |
| R1314 |
T1302 |
T1300 |
arg2Of |
and,upon |
| R1315 |
T1301 |
T1302 |
arg1Of |
MERS,and |
| R1316 |
T1303 |
T1302 |
arg2Of |
SARS,and |
| R13160 |
T63465 |
T42025 |
arg1Of |
virus,strong” |
| R1317 |
T1296 |
T1304 |
arg1Of |
degree,from |
| R13176 |
T55156 |
T17381 |
arg1Of |
vulnerabilities,extensive |
| R1318 |
T1306 |
T1304 |
arg2Of |
analysis,from |
| R1319 |
T1306 |
T1305 |
arg1Of |
analysis,dN/dS |
| R1320 |
T1294 |
T1307 |
arg1Of |
inferring,is |
| R13200 |
T14141 |
T19161 |
arg1Of |
presence,reminiscent |
| R1321 |
T1309 |
T1307 |
arg2Of |
difficult,is |
| R1322 |
T1309 |
T1308 |
arg1Of |
difficult,extremely |
| R13220 |
T87524 |
T52826 |
arg2Of |
immunization,upon |
| R1323 |
T1294 |
T1309 |
arg1Of |
inferring,difficult |
| R1324 |
T1358 |
T1310 |
arg1Of |
be,Importantly |
| R1325 |
T1358 |
T1311 |
arg1Of |
be,"," |
| R1326 |
T1358 |
T1312 |
arg1Of |
be,while |
| R1327 |
T1317 |
T1312 |
arg2Of |
is,while |
| R1328 |
T1314 |
T1313 |
arg1Of |
analyses,similar |
| R13280 |
T7859 |
T53325 |
arg2Of |
neutralising,of |
| R1329 |
T1314 |
T1315 |
arg1Of |
analyses,of |
| R13295 |
T28741 |
T83177 |
arg1Of |
mapping,of |
| R1330 |
T1316 |
T1315 |
arg2Of |
SARS-CoV-2,of |
| R1331 |
T1314 |
T1317 |
arg1Of |
analyses,is |
| R1332 |
T1318 |
T1317 |
arg2Of |
desirable,is |
| R1333 |
T1314 |
T1318 |
arg1Of |
analyses,desirable |
| R13336 |
T19047 |
T57723 |
arg1Of |
analysis,cryo-EM |
| R1334 |
T1317 |
T1319 |
arg1Of |
is,"," |
| R1335 |
T1321 |
T1320 |
arg1Of |
to,due |
| R1336 |
T27779 |
T77953 |
arg1Of |
available,publicly |
| R13361 |
T93669 |
T34640 |
arg2Of |
compositions,determined |
| R1337 |
T1325 |
T1321 |
arg2Of |
variation,to |
| R1338 |
T1325 |
T1322 |
arg1Of |
variation,the |
| R13388 |
T50688 |
T24947 |
arg1Of |
yield,to |
| R1339 |
T1324 |
T1323 |
arg1Of |
genetic,low |
| R1340 |
T1325 |
T1324 |
arg1Of |
variation,genetic |
| R13402 |
T35349 |
T72864 |
arg1Of |
subunits,S1 |
| R1341 |
T1317 |
T1326 |
arg1Of |
is,among |
| R13410 |
T81231 |
T66143 |
arg1Of |
considered,only |
| R1342 |
T1330 |
T1326 |
arg2Of |
sequences,among |
| R1343 |
T1330 |
T1327 |
arg1Of |
sequences,the |
| R1344 |
T1330 |
T1328 |
arg1Of |
sequences,current |
| R1345 |
T1330 |
T1329 |
arg1Of |
sequences,SARS-CoV-2 |
| R1346 |
T1330 |
T1331 |
arg1Of |
sequences,( |
| R1347 |
T1332 |
T1331 |
arg2Of |
as,( |
| R1348 |
T1337 |
T1331 |
arg3Of |
),( |
| R1349 |
T1335 |
T1332 |
arg2Of |
March,as |
| R1350 |
T1334 |
T1333 |
arg1Of |
17,of |
| R1351 |
T1335 |
T1334 |
arg1Of |
March,17 |
| R13511 |
T66804 |
T63689 |
arg2Of |
surface,exposed |
| R1352 |
T1335 |
T1336 |
arg1Of |
March,2020 |
| R1353 |
T1330 |
T1338 |
arg1Of |
sequences,"," |
| R13531 |
T59603 |
T7211 |
arg1Of |
values,( |
| R1354 |
T1330 |
T1339 |
arg1Of |
sequences,which |
| R1355 |
T1341 |
T1340 |
arg1Of |
include,likely |
| R1356 |
T1330 |
T1341 |
arg1Of |
sequences,include |
| R13565 |
T31010 |
T11561 |
arg1Of |
correlation,strong |
| R1357 |
T1343 |
T1341 |
arg2Of |
mutations,include |
| R1358 |
T1343 |
T1342 |
arg1Of |
mutations,deleterious |
| R1359 |
T1343 |
T1344 |
arg1Of |
mutations,that |
| R1360 |
T1343 |
T79570 |
arg1Of |
mutations,will |
| R1361 |
T1347 |
T79570 |
arg2Of |
removed,will |
| R1362 |
T1343 |
T1346 |
arg1Of |
mutations,be |
| R1363 |
T1347 |
T1346 |
arg2Of |
removed,be |
| R1364 |
T1349 |
T1347 |
arg1Of |
selection,removed |
| R13642 |
T40801 |
T50374 |
arg1Of |
are,not |
| R13645 |
T19690 |
T7181 |
arg2Of |
weight,by |
| R1365 |
T1343 |
T1347 |
arg2Of |
mutations,removed |
| R1366 |
T1349 |
T1348 |
arg2Of |
selection,by |
| R1367 |
T1347 |
T1350 |
arg1Of |
removed,over |
| R1368 |
T1351 |
T1350 |
arg2Of |
time,over |
| R13680 |
T53788 |
T33383 |
arg1Of |
functionality,intrinsic |
| R1369 |
T1358 |
T1352 |
arg1Of |
be,"," |
| R1370 |
T1356 |
T1353 |
arg1Of |
analyses,the |
| R1371 |
T1356 |
T1354 |
arg1Of |
analyses,resulting |
| R1372 |
T1356 |
T1355 |
arg1Of |
analyses,bioinformatic |
| R13725 |
T39562 |
T27512 |
arg1Of |
b,SPARX |
| R13727 |
T54604 |
T37933 |
arg2Of |
viruses,and |
| R1373 |
T1356 |
T1357 |
arg1Of |
analyses,would |
| R13730 |
T54044 |
T8441 |
arg2Of |
evasion,in |
| R1374 |
T1358 |
T1357 |
arg2Of |
be,would |
| R1375 |
T1356 |
T1358 |
arg1Of |
analyses,be |
| R1376 |
T1359 |
T1358 |
arg2Of |
unreliable,be |
| R1377 |
T1356 |
T1359 |
arg1Of |
analyses,unreliable |
| R1378 |
T1363 |
T1360 |
arg2Of |
and,Visualising |
| R13781 |
T51449 |
T4483 |
arg1Of |
proteins,fusion |
| R1379 |
T1363 |
T1361 |
arg1Of |
and,the |
| R1380 |
T1362 |
T1363 |
arg1Of |
HIV-1,and |
| R1381 |
T1366 |
T1363 |
arg2Of |
shields,and |
| R1382 |
T1366 |
T1364 |
arg1Of |
shields,SARS |
| R1383 |
T1366 |
T1365 |
arg1Of |
shields,glycan |
| R1384 |
T1363 |
T1367 |
arg1Of |
and,by |
| R1385 |
T1368 |
T1367 |
arg2Of |
cryo-EM,by |
| R1386 |
T48978 |
T21297 |
arg2Of |
antibodies67.Viruses,of |
| R1387 |
T47145 |
T77941 |
arg1Of |
neutralizing,broadly |
| R1388 |
T48978 |
T47145 |
arg1Of |
antibodies67.Viruses,neutralizing |
| R1389 |
T48978 |
T78349 |
arg2Of |
antibodies67.Viruses,classified |
| R1390 |
T78349 |
T84508 |
arg1Of |
classified,as |
| R1391 |
T94485 |
T84508 |
arg2Of |
"strong”26,56",as |
| R1392 |
T94485 |
T99687 |
arg1Of |
"strong”26,56",“evasion |
| R1393 |
T80263 |
T8371 |
arg1Of |
development,may |
| R1394 |
T19557 |
T8371 |
arg2Of |
differ,may |
| R1395 |
T19557 |
T70765 |
arg1Of |
differ,then |
| R1396 |
T80263 |
T19557 |
arg1Of |
development,differ |
| R1397 |
T58964 |
T68211 |
arg1Of |
to,due |
| R1398 |
T19557 |
T58964 |
arg1Of |
differ,to |
| R1399 |
T28724 |
T58964 |
arg2Of |
efficacies,to |
| R1400 |
T28724 |
T91845 |
arg1Of |
efficacies,varied |
| R1401 |
T29672 |
T24787 |
arg1Of |
datasets,cryo-EM |
| R14014 |
T1508 |
T33829 |
arg1Of |
boundaries,diffuse |
| R1402 |
T91764 |
T35775 |
arg2Of |
shielding,of |
| R1403 |
T91764 |
T42494 |
arg1Of |
shielding,protein |
| R1404 |
T91764 |
T48391 |
arg1Of |
shielding,surface |
| R1405 |
T97622 |
T4001 |
arg1Of |
comparisons,meaningful |
| R14059 |
T71776 |
T64977 |
arg2Of |
interactions,of |
| R1406 |
T1370 |
T1369 |
arg2Of |
glycans,by |
| R1407 |
T1375 |
T1371 |
arg1Of |
adds,Overall |
| R14070 |
T7550 |
T70799 |
arg1Of |
accumulation,of |
| R1408 |
T1375 |
T1372 |
arg1Of |
adds,"," |
| R14083 |
T52475 |
T17084 |
arg1Of |
conservation,on |
| R1409 |
T1374 |
T1373 |
arg1Of |
study,this |
| R1410 |
T29096 |
T42685 |
arg1Of |
modifications,the |
| R1411 |
T1377 |
T1375 |
arg2Of |
evidence,adds |
| R1412 |
T1377 |
T1376 |
arg1Of |
evidence,further |
| R1413 |
T1377 |
T1378 |
arg1Of |
evidence,suggesting |
| R1414 |
T1393 |
T1378 |
arg2Of |
constitute,suggesting |
| R14145 |
T18648 |
T52275 |
arg2Of |
interactions,reveal |
| R1415 |
T1393 |
T1379 |
arg1Of |
constitute,that |
| R1416 |
T1383 |
T1380 |
arg1Of |
modifications,extensive |
| R1417 |
T1383 |
T1381 |
arg1Of |
modifications,N-linked |
| R1418 |
T1383 |
T1382 |
arg1Of |
modifications,glycan |
| R14182 |
T35915 |
T84730 |
arg1Of |
structure,the |
| R1419 |
T1383 |
T1384 |
arg1Of |
modifications,of |
| R1420 |
T1390 |
T1384 |
arg2Of |
proteins,of |
| R1421 |
T1390 |
T47921 |
arg1Of |
proteins,SARS |
| R14219 |
T32211 |
T36441 |
arg1Of |
elicit,"," |
| R1422 |
T47921 |
T1386 |
arg1Of |
SARS,and |
| R14228 |
T85438 |
T20968 |
arg1Of |
",",and |
| R1423 |
T1387 |
T1386 |
arg2Of |
MERS,and |
| R1424 |
T1390 |
T1387 |
arg1Of |
proteins,MERS |
| R1425 |
T1390 |
T1388 |
arg1Of |
proteins,CoV |
| R1426 |
T1390 |
T1389 |
arg1Of |
proteins,S |
| R14263 |
T16458 |
T39264 |
arg1Of |
dataset52,SARS |
| R1427 |
T1383 |
T1391 |
arg1Of |
modifications,do |
| R1428 |
T1393 |
T1391 |
arg2Of |
constitute,do |
| R1429 |
T1393 |
T1392 |
arg1Of |
constitute,not |
| R1430 |
T1383 |
T1393 |
arg1Of |
modifications,constitute |
| R1431 |
T1396 |
T1393 |
arg2Of |
shield,constitute |
| R1432 |
T1396 |
T1394 |
arg1Of |
shield,an |
| R1433 |
T1396 |
T1395 |
arg1Of |
shield,effective |
| R1434 |
T1393 |
T1397 |
arg1Of |
constitute,"," |
| R1435 |
T1393 |
T1398 |
arg1Of |
constitute,in |
| R1436 |
T1399 |
T1398 |
arg2Of |
comparison,in |
| R14360 |
T44352 |
T99300 |
arg2Of |
shielding,of |
| R1437 |
T1399 |
T1400 |
arg1Of |
comparison,to |
| R1438 |
T1402 |
T1400 |
arg2Of |
shields,to |
| R1439 |
T1402 |
T1401 |
arg1Of |
shields,glycan |
| R1440 |
T1402 |
T1403 |
arg1Of |
shields,of |
| R1441 |
T1406 |
T1403 |
arg2Of |
viruses,of |
| R14418 |
T86335 |
T7181 |
arg1Of |
glycan,by |
| R1442 |
T1406 |
T1404 |
arg1Of |
viruses,certain |
| R14422 |
T69877 |
T33142 |
arg2Of |
trimers,as |
| R14427 |
T14374 |
T44329 |
arg1Of |
graphs,bar |
| R1443 |
T1406 |
T1405 |
arg1Of |
viruses,other |
| R1444 |
T1377 |
T1407 |
arg1Of |
evidence,"," |
| R1445 |
T1377 |
T1408 |
arg1Of |
evidence,which |
| R14458 |
T6494 |
T33346 |
arg2Of |
sites,for |
| R1446 |
T1377 |
T1409 |
arg1Of |
evidence,is |
| R1447 |
T1410 |
T1409 |
arg2Of |
reflected,is |
| R14478 |
T10370 |
T60922 |
arg2Of |
density,for |
| R1448 |
T1414 |
T1410 |
arg1Of |
structure,reflected |
| R1449 |
T1377 |
T1410 |
arg2Of |
evidence,reflected |
| R1450 |
T1414 |
T1411 |
arg2Of |
structure,by |
| R14505 |
T91428 |
T10009 |
arg1Of |
we,studied |
| R1451 |
T1414 |
T1412 |
arg1Of |
structure,the |
| R1452 |
T1414 |
T1413 |
arg1Of |
structure,overall |
| R14520 |
T10370 |
T57613 |
arg1Of |
density,global |
| R1453 |
T1414 |
T1415 |
arg1Of |
structure,"," |
| R14533 |
T30171 |
T64135 |
arg2Of |
6OHY,"," |
| R1454 |
T1417 |
T1415 |
arg2Of |
and,"," |
| R1455 |
T1416 |
T1417 |
arg1Of |
density,and |
| R1456 |
T1419 |
T1417 |
arg2Of |
abundance,and |
| R1457 |
T1419 |
T1418 |
arg1Of |
abundance,oligomannose |
| R14572 |
T77334 |
T68472 |
arg1Of |
We,using |
| R1458 |
T1417 |
T1420 |
arg1Of |
and,across |
| R14580 |
T38160 |
T20315 |
arg1Of |
",","," |
| R1459 |
T1424 |
T1420 |
arg2Of |
glycoproteins,across |
| R14590 |
T72680 |
T6297 |
arg2Of |
linked,is |
| R14595 |
T20998 |
T24864 |
arg1Of |
regions,patch |
| R1460 |
T1424 |
T1421 |
arg1Of |
glycoproteins,the |
| R1461 |
T1424 |
T1422 |
arg1Of |
glycoproteins,corresponding |
| R1462 |
T1424 |
T1423 |
arg1Of |
glycoproteins,trimeric |
| R1463 |
T1427 |
T1426 |
arg1Of |
demonstrate,also |
| R1464 |
T1425 |
T1427 |
arg1Of |
We,demonstrate |
| R1465 |
T1432 |
T1427 |
arg2Of |
occurs,demonstrate |
| R14652 |
T90347 |
T69433 |
arg1Of |
proteins,coronavirus |
| R1466 |
T1432 |
T1428 |
arg1Of |
occurs,that |
| R1467 |
T1430 |
T1429 |
arg1Of |
diversification,amino-acid |
| R14674 |
T68539 |
T22023 |
arg1Of |
glycans,been |
| R1468 |
T1432 |
T1431 |
arg1Of |
occurs,indeed |
| R1469 |
T1430 |
T1432 |
arg1Of |
diversification,occurs |
| R1470 |
T1432 |
T1433 |
arg1Of |
occurs,at |
| R14706 |
T30294 |
T51996 |
arg2Of |
densities,calculated |
| R1471 |
T1436 |
T1433 |
arg2Of |
regions,at |
| R1472 |
T1436 |
T1434 |
arg1Of |
regions,antibody |
| R1473 |
T19555 |
T26714 |
arg1Of |
importance,of |
| R1474 |
T1436 |
T1437 |
arg1Of |
regions,on |
| R14742 |
T17551 |
T54237 |
arg1Of |
shields,glycan |
| R1475 |
T1439 |
T1437 |
arg2Of |
trimer,on |
| R1476 |
T1439 |
T1438 |
arg1Of |
trimer,the |
| R1477 |
T1439 |
T1440 |
arg1Of |
trimer,"," |
| R1478 |
T1439 |
T1441 |
arg1Of |
trimer,which |
| R1479 |
T1439 |
T1442 |
arg1Of |
trimer,confirms |
| R1480 |
T1445 |
T1442 |
arg2Of |
play,confirms |
| R1481 |
T1445 |
T1443 |
arg1Of |
play,that |
| R1482 |
T1444 |
T1445 |
arg1Of |
glycans,play |
| R1483 |
T1447 |
T1445 |
arg2Of |
role,play |
| R1484 |
T1447 |
T1446 |
arg1Of |
role,a |
| R1485 |
T1445 |
T1448 |
arg1Of |
play,in |
| R14857 |
T50530 |
T67487 |
arg2Of |
lack,and |
| R1486 |
T1449 |
T1448 |
arg2Of |
occluding,in |
| R1487 |
T1451 |
T1449 |
arg2Of |
regions,occluding |
| R14872 |
T15993 |
T79196 |
arg2Of |
presence,by |
| R1488 |
T1451 |
T1450 |
arg1Of |
regions,specific |
| R1489 |
T1451 |
T1452 |
arg1Of |
regions,if |
| R1490 |
T1453 |
T1452 |
arg2Of |
vulnerability,if |
| R14902 |
T75554 |
T98585 |
arg1Of |
spikes,coronavirus |
| R1491 |
T1453 |
T1454 |
arg1Of |
vulnerability,on |
| R1492 |
T1456 |
T1454 |
arg2Of |
glycoprotein,on |
| R1493 |
T1456 |
T1455 |
arg1Of |
glycoprotein,the |
| R1494 |
T1478 |
T1457 |
arg1Of |
and,Furthermore |
| R1495 |
T1478 |
T1458 |
arg1Of |
and,"," |
| R1496 |
T1459 |
T1460 |
arg1Of |
comparisons,between |
| R1497 |
T1462 |
T1460 |
arg2Of |
shields,between |
| R1498 |
T1462 |
T1461 |
arg1Of |
shields,glycan |
| R1499 |
T1462 |
T1463 |
arg1Of |
shields,from |
| R1500 |
T1465 |
T1463 |
arg2Of |
number,from |
| R1501 |
T1465 |
T1464 |
arg1Of |
number,a |
| R1502 |
T1465 |
T1466 |
arg1Of |
number,of |
| R1503 |
T1467 |
T1466 |
arg2Of |
viruses,of |
| R1504 |
T1459 |
T1468 |
arg1Of |
comparisons,highlight |
| R15047 |
T97839 |
T6523 |
arg1Of |
note,interesting |
| R15048 |
T69932 |
T42110 |
arg1Of |
define,to |
| R1505 |
T1470 |
T1468 |
arg2Of |
importance,highlight |
| R1506 |
T1470 |
T1469 |
arg1Of |
importance,the |
| R1507 |
T1470 |
T1471 |
arg1Of |
importance,of |
| R1508 |
T1474 |
T1471 |
arg2Of |
shield,of |
| R15085 |
T88882 |
T76117 |
arg1Of |
subject,to |
| R1509 |
T1474 |
T1472 |
arg1Of |
shield,a |
| R1510 |
T1474 |
T1473 |
arg1Of |
shield,glycan |
| R1511 |
T1474 |
T1475 |
arg1Of |
shield,in |
| R1512 |
T1477 |
T1475 |
arg2Of |
evasion,in |
| R1513 |
T1477 |
T1476 |
arg1Of |
evasion,immune |
| R1514 |
T77242 |
T85214 |
arg2Of |
S,and |
| R1515 |
T1479 |
T1478 |
arg2Of |
reveal,and |
| R1516 |
T1459 |
T1479 |
arg1Of |
comparisons,reveal |
| R1517 |
T1481 |
T1479 |
arg2Of |
principles,reveal |
| R1518 |
T1481 |
T1480 |
arg1Of |
principles,structural |
| R1519 |
T1481 |
T1482 |
arg1Of |
principles,that |
| R1520 |
T1481 |
T1483 |
arg1Of |
principles,govern |
| R1521 |
T1485 |
T1483 |
arg2Of |
status,govern |
| R15217 |
T98451 |
T72837 |
arg1Of |
diversities,were |
| R15219 |
T19555 |
T1601 |
arg1Of |
importance,been |
| R1522 |
T1485 |
T1484 |
arg1Of |
status,glycosylation |
| R15227 |
T84875 |
T83072 |
arg1Of |
generated,"," |
| R1523 |
T1487 |
T1488 |
arg1Of |
Expression,and |
| R15238 |
T28741 |
T27583 |
arg1Of |
mapping,11 glycoproteins. Structural-based |
| R1524 |
T1489 |
T1488 |
arg2Of |
purification,and |
| R1525 |
T1488 |
T1490 |
arg1Of |
and,of |
| R15252 |
T7879 |
T87072 |
arg1Of |
structure,the |
| R1526 |
T1493 |
T1490 |
arg2Of |
glycoproteins,of |
| R1527 |
T1493 |
T1491 |
arg1Of |
glycoproteins,coronavirus |
| R15276 |
T10053 |
T41377 |
arg1Of |
speculate,for |
| R1528 |
T1493 |
T1492 |
arg1Of |
glycoproteins,spike |
| R15307 |
T82356 |
T8758 |
arg1Of |
diversity,Amino-acid |
| R15309 |
T83803 |
T92642 |
arg2Of |
M9,( |
| R15321 |
T95182 |
T88912 |
arg1Of |
",",compared |
| R15327 |
T31301 |
T73600 |
arg1Of |
and,"," |
| R15347 |
T96477 |
T7804 |
arg2Of |
amino-acids,of |
| R15384 |
T81925 |
T31179 |
arg2Of |
proteins,and |
| R15450 |
T98451 |
T74584 |
arg1Of |
diversities,per-site |
| R15452 |
T27050 |
T89403 |
arg2Of |
microscopy,used |
| R15459 |
T67976 |
T12260 |
arg1Of |
glycome,of |
| R15545 |
T87865 |
T32032 |
arg1Of |
observed,experimentally |
| R15555 |
T39941 |
T13595 |
arg1Of |
genes,spike |
| R15611 |
T4820 |
T60050 |
arg1Of |
observed,experimentally |
| R15613 |
T95495 |
T73178 |
arg1Of |
grey,dark |
| R15619 |
T72369 |
T13118 |
arg1Of |
substitutions,synonymous |
| R15665 |
T37921 |
T34206 |
arg1Of |
glycans,fewer |
| R15678 |
T59734 |
T50969 |
arg1Of |
constraints,limit |
| R15715 |
T25304 |
T83161 |
arg1Of |
sequences,gene |
| R1577 |
T86504 |
T76573 |
arg2Of |
alkylated,"," |
| R15842 |
T77976 |
T39650 |
arg3Of |
),( |
| R15889 |
T1566 |
T58559 |
arg1Of |
opposed,to |
| R1589 |
T75686 |
T16671 |
arg1Of |
proteins,S |
| R1590 |
T54985 |
T54383 |
arg1Of |
proteins,S |
| R15971 |
T54061 |
T35585 |
arg1Of |
proteins,SARS |
| R16019 |
T56943 |
T93082 |
arg2Of |
them,adding |
| R16052 |
T11220 |
T31109 |
arg1Of |
dynamics,therefore |
| R16055 |
T43156 |
T80529 |
arg1Of |
intervals,posterior |
| R16084 |
T29000 |
T84846 |
arg1Of |
sparser,considerably |
| R16092 |
T20594 |
T76109 |
arg1Of |
residues,undergoing |
| R16112 |
T50640 |
T17100 |
arg2Of |
and,with |
| R16162 |
T10541 |
T7434 |
arg2Of |
viruses,between |
| R1617 |
T65828 |
T1385 |
arg2Of |
residues,exposed |
| R16170 |
T96660 |
T18812 |
arg1Of |
and,"," |
| R1625 |
T93681 |
T72733 |
modOf |
HAs,replacing |
| R16270 |
T32624 |
T57322 |
arg1Of |
diversity,and |
| R16285 |
T72412 |
T77964 |
arg2Of |
why,understanding |
| R16310 |
T22368 |
T83476 |
arg1Of |
25,% |
| R16314 |
T64331 |
T35591 |
arg1Of |
ratios,of |
| R16336 |
T80158 |
T82660 |
arg2Of |
SI,( |
| R16454 |
T17681 |
T76597 |
arg1Of |
candidates,many |
| R16468 |
T86925 |
T55384 |
arg2Of |
series,with |
| R16504 |
T2686 |
T88226 |
arg1Of |
shield,glycan |
| R16533 |
T87179 |
T16494 |
arg1Of |
receptor-binding,and |
| R16567 |
T9264 |
T70541 |
arg1Of |
reveal,and |
| R16607 |
T87051 |
T82847 |
arg1Of |
it,performing |
| R16608 |
T94778 |
T33023 |
arg1Of |
as,such |
| R16669 |
T76361 |
T69629 |
arg1Of |
proteins,coronavirus |
| R16680 |
T61476 |
T68346 |
arg1Of |
residues,amino-acid |
| R16719 |
T47420 |
T67617 |
arg1Of |
number,by |
| R16738 |
T43420 |
T94778 |
arg2Of |
and,as |
| R16751 |
T66049 |
T12116 |
arg1Of |
shield,glycan |
| R16805 |
T17681 |
T40686 |
arg1Of |
candidates,produce |
| R16806 |
T44869 |
T14663 |
arg1Of |
in,especially |
| R1686 |
T72393 |
T49131 |
arg1Of |
reprocessed,for |
| R16879 |
T86817 |
T18984 |
arg1Of |
",","," |
| R16896 |
T54925 |
T93480 |
arg1Of |
analyses,83 |
| R1691 |
T32211 |
T66786 |
arg1Of |
elicit,readily |
| R16925 |
T69499 |
T83087 |
arg1Of |
Analysis,revealed |
| R17066 |
T16685 |
T55814 |
arg1Of |
is,and |
| R17073 |
T88079 |
T2448 |
arg2Of |
5X58,( |
| R17114 |
T25443 |
T97762 |
arg1Of |
MERS,was |
| R17152 |
T17645 |
T50138 |
arg1Of |
sites,glycosylation |
| R17171 |
T38543 |
T43155 |
arg2Of |
glycosylated,are |
| R17192 |
T65590 |
T39600 |
arg2Of |
5I08,"," |
| R17257 |
T60774 |
T72458 |
arg1Of |
sites,N-linked |
| R17294 |
T10460 |
T54967 |
arg1Of |
and,"," |
| R17315 |
T88607 |
T60015 |
arg1Of |
We,hypothesized |
| R17326 |
T81576 |
T74525 |
arg2Of |
underprocessed,but |
| R17472 |
T56514 |
T39313 |
arg1Of |
population,the |
| R17506 |
T87991 |
T17443 |
arg3Of |
),( |
| R17597 |
T19555 |
T74546 |
arg2Of |
importance,investigated |
| R17624 |
T40146 |
T80516 |
arg2Of |
evasion,aid |
| R17631 |
T16169 |
T29335 |
arg1Of |
interpretability,the |
| R17670 |
T72197 |
T88581 |
arg1Of |
glycoproteins,different |
| R17713 |
T75686 |
T13582 |
arg2Of |
proteins,and |
| R1774 |
T16169 |
T54909 |
arg1Of |
interpretability,of |
| R17754 |
T32200 |
T61088 |
arg1Of |
antibodies,targeted |
| R17774 |
T79412 |
T54950 |
arg1Of |
is,"," |
| R17775 |
T26472 |
T18939 |
arg1Of |
subunit,between |
| R17784 |
T82842 |
T94035 |
arg1Of |
5X59,and |
| R17818 |
T17113 |
T15012 |
arg2Of |
proteins,Purified |
| R17876 |
T99242 |
T42499 |
arg2Of |
head,on |
| R17920 |
T78856 |
T67170 |
arg2Of |
research,in |
| R17934 |
T86925 |
T19908 |
arg1Of |
series,glycan |
| R1794 |
T7879 |
T75651 |
arg1Of |
structure,of |
| R17970 |
T74594 |
T32963 |
arg1Of |
structure,of |
| R17994 |
T76109 |
T87805 |
arg2Of |
undergoing,be |
| R18003 |
T14034 |
T76136 |
arg2Of |
processing,increased |
| R18040 |
T8574 |
T96535 |
arg1Of |
highlighted,throughout |
| R18043 |
T14374 |
T86682 |
arg1Of |
graphs,The |
| R18044 |
T47125 |
T30265 |
arg2Of |
results,reproduced |
| R18076 |
T61501 |
T25318 |
arg2Of |
",",of |
| R18121 |
T68396 |
T90251 |
arg2Of |
MS,by |
| R18139 |
T92287 |
T2494 |
arg1Of |
exhibited,that |
| R18142 |
T80657 |
T46816 |
arg1Of |
protein,that |
| R18144 |
T2440 |
T89662 |
arg1Of |
glycoproteins,S |
| R18285 |
T72291 |
T87030 |
arg1Of |
colored,"," |
| R18293 |
T88079 |
T12743 |
arg1Of |
5X58,ID |
| R18321 |
T88747 |
T79957 |
arg2Of |
observed,been |
| R18386 |
T89744 |
T37340 |
arg1Of |
antibodies,targeting |
| R18448 |
T35349 |
T72291 |
arg2Of |
subunits,colored |
| R18453 |
T80844 |
T21892 |
arg1Of |
networks,the |
| R18524 |
T46478 |
T60028 |
arg1Of |
domain,each |
| R18543 |
T92271 |
T41451 |
arg1Of |
rate66,the |
| R18556 |
T86418 |
T9745 |
arg2Of |
defined,as |
| R18633 |
T82481 |
T42862 |
arg1Of |
subunit,S1 |
| R18674 |
T93319 |
T88231 |
arg1Of |
domains,"," |
| R18729 |
T66354 |
T72680 |
arg2Of |
shielding,linked |
| R18750 |
T9951 |
T15001 |
arg1Of |
located,on |
| R18785 |
T39465 |
T17574 |
arg1Of |
“shields”,the |
| R18805 |
T14361 |
T29834 |
arg2Of |
outbreak,within |
| R18813 |
T2440 |
T47096 |
arg1Of |
glycoproteins,b |
| R18814 |
T61777 |
T13379 |
arg1Of |
maps,both |
| R18870 |
T43889 |
T37781 |
arg1Of |
GPC24,LASV |
| R18918 |
T92110 |
T35748 |
arg1Of |
glycans,on |
| R18920 |
T33538 |
T23766 |
arg1Of |
glycosylation,reach |
| R18949 |
T44762 |
T97123 |
arg1Of |
labelled,with |
| R18950 |
T73114 |
T38463 |
arg1Of |
compare,it |
| R18961 |
T18666 |
T25962 |
arg2Of |
spectrometry,to |
| R19033 |
T82693 |
T72819 |
arg1Of |
and,"," |
| R19042 |
T80657 |
T55541 |
arg1Of |
protein,a |
| R19054 |
T15422 |
T38271 |
arg1Of |
surface,proteinaceous |
| R19111 |
T49977 |
T8049 |
arg2Of |
responses,and |
| R19115 |
T45890 |
T78652 |
arg3Of |
),( |
| R19195 |
T69491 |
T78299 |
arg1Of |
estimates,dN/dS |
| R19229 |
T49127 |
T17734 |
arg1Of |
ID,PDB |
| R19231 |
T77537 |
T45819 |
arg1Of |
shield,a |
| R19265 |
T66921 |
T68204 |
arg2Of |
they,measured |
| R19288 |
T96908 |
T30425 |
arg2Of |
based,are |
| R19289 |
T26975 |
T72222 |
arg1Of |
network,an |
| R19300 |
T29223 |
T2696 |
arg1Of |
glycans,occluded |
| R19325 |
T58264 |
T19959 |
arg2Of |
competent,remaining |
| R19327 |
T35287 |
T63281 |
arg1Of |
virus,chimpanzee |
| R19366 |
T68699 |
T41652 |
arg1Of |
presented,as |
| R19392 |
T10175 |
T79176 |
arg1Of |
spectrometry,negative-ion |
| R19405 |
T23666 |
T67118 |
arg3Of |
),( |
| R19443 |
T90266 |
T24380 |
arg1Of |
SARS,and |
| R19445 |
T24421 |
T82839 |
arg1Of |
MERS,trimeric |
| R19464 |
T1949 |
T77796 |
arg1Of |
diversity,the |
| R19513 |
T28812 |
T74425 |
arg1Of |
phenomenon,This |
| R19514 |
T72703 |
T40990 |
arg1Of |
levels,of |
| R19546 |
T27860 |
T89667 |
arg1Of |
events,characterized |
| R19617 |
T58264 |
T60128 |
arg1Of |
competent,functionally |
| R19622 |
T36749 |
T90326 |
arg1Of |
co-localize,that |
| R1966 |
T68640 |
T82313 |
arg1Of |
proteins,b |
| R19683 |
T1670 |
T13557 |
arg2Of |
trimming,enhanced |
| R19684 |
T84232 |
T1963 |
arg1Of |
"lectins47,48",implicated |
| R19725 |
T83973 |
T30617 |
arg2Of |
residues,between |
| R19742 |
T55216 |
T19328 |
arg1Of |
We,suggest |
| R19805 |
T27945 |
T76460 |
arg1Of |
residues,amino-acid |
| R19873 |
T99530 |
T31843 |
arg1Of |
analysis,glycan |
| R19912 |
T74716 |
T46731 |
arg2Of |
is,Given |
| R19941 |
T66804 |
T9316 |
arg1Of |
surface,can |
| R20006 |
T14141 |
T38719 |
arg1Of |
presence,is |
| R20022 |
T9018 |
T54890 |
arg2Of |
N-terminal,and |
| R20046 |
T77842 |
T99218 |
arg1Of |
away,from |
| R20067 |
T75213 |
T82633 |
arg1Of |
peptide,fusion |
| R20103 |
T62341 |
T16494 |
arg2Of |
membrane,and |
| R20104 |
T67026 |
T21495 |
arg1Of |
domains,were |
| R20111 |
T47420 |
T65408 |
arg2Of |
number,dividing |
| R20171 |
T17113 |
T24811 |
arg1Of |
proteins,S |
| R20306 |
T28724 |
T35775 |
arg1Of |
efficacies,of |
| R20308 |
T93961 |
T27490 |
arg2Of |
colored,are |
| R20313 |
T54604 |
T67339 |
arg2Of |
viruses,classified |
| R20318 |
T90583 |
T6621 |
arg1Of |
and,contribute |
| R20355 |
T32345 |
T90583 |
arg2Of |
environment,and |
| R20363 |
T80637 |
T20315 |
arg2Of |
S,"," |
| R20431 |
T10460 |
T76296 |
arg2Of |
and,were |
| R20433 |
T43889 |
T51710 |
arg2Of |
GPC24,"," |
| R20473 |
T76185 |
T35489 |
arg1Of |
b,S |
| R20505 |
T14682 |
T19094 |
arg1Of |
MERS,has |
| R20662 |
T30499 |
T86749 |
arg2Of |
accessibility,to |
| R20667 |
T15651 |
T15044 |
arg1Of |
resolution,and |
| R20744 |
T52589 |
T75194 |
arg3Of |
),( |
| R20757 |
T82481 |
T63639 |
arg1Of |
subunit,"," |
| R20758 |
T32700 |
T66481 |
arg2Of |
is,Although |
| R20779 |
T6629 |
T88912 |
arg2Of |
compositions,compared |
| R20784 |
T76185 |
T7560 |
arg1Of |
b,11 and |
| R20962 |
T28935 |
T19712 |
arg1Of |
behaviour,the |
| R20973 |
T82847 |
T85203 |
arg2Of |
performing,of |
| R21035 |
T99013 |
T49752 |
arg2Of |
Fig. 4,( |
| R21039 |
T1317 |
T1321 |
arg1Of |
is,to |
| R21042 |
T63130 |
T21020 |
arg2Of |
surface,on |
| R21082 |
T43304 |
T48004 |
arg1Of |
Same,in |
| R21139 |
T12305 |
T59830 |
arg1Of |
and,elevated |
| R21190 |
T28685 |
T41253 |
arg1Of |
proteins,viral |
| R21203 |
T83381 |
T99370 |
arg2Of |
glycosylation,exhibits |
| R21230 |
T67621 |
T26015 |
arg1Of |
hand,one |
| R21251 |
T10053 |
T20635 |
arg1Of |
speculate,to |
| R21254 |
T46357 |
T1834 |
arg2Of |
differences,of |
| R21261 |
T72195 |
T8288 |
arg1Of |
recognition,immune |
| R21298 |
T94857 |
T43870 |
arg1Of |
Mapping,values. |
| R21418 |
T91852 |
T19623 |
arg2Of |
amenability,to |
| R21450 |
T15627 |
T32529 |
arg1Of |
nanobodies,could |
| R2149 |
T28685 |
T25202 |
arg1Of |
proteins,class |
| R21530 |
T49099 |
T69890 |
arg1Of |
domain,the |
| R21540 |
T1932 |
T24463 |
arg2Of |
glycoproteins,of |
| R21549 |
T89162 |
T78379 |
arg1Of |
as,"," |
| R21565 |
T44453 |
T67014 |
arg1Of |
densities,glycan |
| R21612 |
T69286 |
T52989 |
arg1Of |
calculated,as |
| R21723 |
T43286 |
T74010 |
arg1Of |
penetrate,easily |
| R2173 |
T70323 |
T13755 |
arg1Of |
proteins,the |
| R21732 |
T63281 |
T79382 |
arg2Of |
chimpanzee,and |
| R21771 |
T21366 |
T33467 |
arg1Of |
sites,the |
| R21820 |
T74879 |
T16401 |
arg2Of |
SARS,and |
| R21828 |
T50771 |
T10053 |
arg1Of |
it,speculate |
| R21857 |
T7775 |
T17162 |
arg2Of |
residues,colored |
| R21880 |
T11435 |
T61578 |
arg2Of |
advantage,of |
| R21904 |
T91852 |
T39634 |
arg1Of |
amenability,its |
| R21921 |
T13068 |
T25400 |
arg1Of |
functionality,of |
| R21926 |
T36749 |
T32785 |
arg2Of |
co-localize,revealed |
| R21940 |
T7370 |
T66013 |
arg2Of |
isolated,appear |
| R21990 |
T54985 |
T68699 |
arg2Of |
proteins,presented |
| R22049 |
T73178 |
T24147 |
arg2Of |
dark,and |
| R2207 |
T36158 |
T62312 |
arg2Of |
BG505,( |
| R22078 |
T91764 |
T1369 |
arg1Of |
shielding,by |
| R221 |
T225 |
T226 |
arg1Of |
Coronaviruses,( |
| R22100 |
T18180 |
T83144 |
arg1Of |
shielding,glycan |
| R22134 |
T8143 |
T17900 |
arg2Of |
chymotrypsin,plus |
| R22147 |
T66936 |
T12725 |
arg2Of |
number,divided |
| R22162 |
T76109 |
T65773 |
arg1Of |
undergoing,that |
| R22163 |
T97323 |
T48816 |
arg1Of |
HIV-1,and |
| R222 |
T227 |
T226 |
arg2Of |
CoVs,( |
| R22266 |
T21366 |
T99523 |
arg1Of |
sites,N-linked |
| R223 |
T228 |
T226 |
arg3Of |
),( |
| R224 |
T225 |
T229 |
arg1Of |
Coronaviruses,are |
| R22404 |
T56951 |
T84875 |
arg1Of |
we,generated |
| R2241 |
T5616 |
T25906 |
arg1Of |
HAs,where |
| R2243 |
T91020 |
T28189 |
arg2Of |
Man9GlcNAc2,; |
| R22442 |
T28812 |
T88747 |
arg2Of |
phenomenon,observed |
| R22461 |
T65162 |
T15804 |
arg2Of |
titres,elicit |
| R22467 |
T55408 |
T6521 |
arg1Of |
ratio,a |
| R22476 |
T79677 |
T96638 |
arg1Of |
maps,The |
| R225 |
T231 |
T229 |
arg2Of |
pathogens,are |
| R22503 |
T19388 |
T8292 |
arg2Of |
al.51,from |
| R22521 |
T74546 |
T1601 |
arg2Of |
investigated,been |
| R22544 |
T17681 |
T32770 |
arg1Of |
candidates,potential |
| R22561 |
T68778 |
T11621 |
arg1Of |
it,offer |
| R226 |
T231 |
T230 |
arg2Of |
pathogens,enveloped |
| R2263 |
T40721 |
T2753 |
arg1Of |
panel,: |
| R2265 |
T70745 |
T16791 |
arg2Of |
families,between |
| R22666 |
T72680 |
T21071 |
arg1Of |
linked,to |
| R22690 |
T97014 |
T88817 |
arg1Of |
response,the |
| R22697 |
T69826 |
T25808 |
arg1Of |
glycoprotein,the |
| R227 |
T231 |
T232 |
arg1Of |
pathogens,responsible |
| R22723 |
T67337 |
T52338 |
arg2Of |
cluster,in |
| R2273 |
T43156 |
T53375 |
arg1Of |
intervals,95 |
| R22758 |
T20304 |
T50152 |
arg1Of |
differences,i.e. |
| R228 |
T232 |
T233 |
arg1Of |
responsible,for |
| R22808 |
T38040 |
T52822 |
arg2Of |
structure,visualize |
| R22859 |
T54866 |
T20906 |
arg1Of |
glycans,N-linked |
| R22862 |
T64096 |
T56477 |
arg1Of |
this,is |
| R22864 |
T76651 |
T80310 |
arg1Of |
assortment,an |
| R22881 |
T52475 |
T31921 |
arg1Of |
conservation,the |
| R229 |
T236 |
T233 |
arg2Of |
disorders,for |
| R2290 |
T30265 |
T9777 |
arg1Of |
reproduced,while |
| R22945 |
T78120 |
T36313 |
arg1Of |
2D-variability,significant |
| R22986 |
T37597 |
T2700 |
arg1Of |
data,the |
| R22989 |
T41479 |
T52989 |
arg2Of |
number,as |
| R230 |
T236 |
T234 |
arg1Of |
disorders,multiple |
| R23030 |
T37852 |
T79086 |
arg3Of |
),( |
| R23056 |
T17645 |
T77299 |
arg1Of |
sites,be |
| R23058 |
T38777 |
T93386 |
arg1Of |
densities,glycan |
| R23066 |
T6494 |
T57622 |
arg1Of |
sites,of |
| R2307 |
T97136 |
T78671 |
arg1Of |
greater,far |
| R23093 |
T5616 |
T39729 |
arg1Of |
HAs,influenza |
| R231 |
T236 |
T235 |
arg1Of |
disorders,respiratory |
| R23134 |
T93322 |
T75735 |
arg1Of |
context,a |
| R23158 |
T68442 |
T32176 |
arg2Of |
domains,disordered |
| R23171 |
T38606 |
T47548 |
arg1Of |
GPC,was |
| R23177 |
T30435 |
T87545 |
arg1Of |
targeted,to |
| R23178 |
T73114 |
T32700 |
arg1Of |
compare,is |
| R23197 |
T31301 |
T2424 |
arg1Of |
and,ID |
| R232 |
T236 |
T237 |
arg1Of |
disorders,of |
| R23203 |
T71298 |
T49403 |
arg1Of |
glycoproteins,viral |
| R23230 |
T36749 |
T5951 |
arg1Of |
co-localize,"," |
| R23242 |
T89162 |
T9264 |
arg1Of |
as,reveal |
| R23244 |
T68543 |
T71248 |
arg2Of |
glycoproteins,expressed |
| R23260 |
T79346 |
T89551 |
arg2Of |
route,offer |
| R23288 |
T36749 |
T66900 |
arg1Of |
co-localize,to |
| R2329 |
T43357 |
T40990 |
arg2Of |
pressure,of |
| R233 |
T239 |
T237 |
arg2Of |
severity,of |
| R23301 |
T52371 |
T61083 |
arg1Of |
SARS,and |
| R2333 |
T63488 |
T59510 |
arg3Of |
:,( |
| R23393 |
T80500 |
T32298 |
arg1Of |
residues,the |
| R234 |
T239 |
T238 |
arg1Of |
severity,varying |
| R23417 |
T99047 |
T51798 |
arg2Of |
green,( |
| R2347 |
T53051 |
T78843 |
arg1Of |
Env,SIV |
| R23484 |
T13499 |
T90583 |
arg1Of |
differences,and |
| R235 |
T239 |
T240 |
arg1Of |
severity,in |
| R23537 |
T93961 |
T72784 |
arg1Of |
colored,according |
| R23575 |
T21233 |
T50993 |
arg1Of |
published,previously |
| R23595 |
T57983 |
T88640 |
arg1Of |
"shield54,55",glycan |
| R236 |
T241 |
T240 |
arg2Of |
humans1,in |
| R23692 |
T3337 |
T63380 |
arg1Of |
shield51,HIV-1 |
| R237 |
T243 |
T242 |
arg1Of |
CoVs,Certain |
| R23718 |
T2686 |
T35212 |
arg2Of |
shield,in |
| R23723 |
T91373 |
T23968 |
arg2Of |
and,exhibits |
| R23725 |
T21366 |
T38634 |
arg2Of |
sites,of |
| R23741 |
T62840 |
T86654 |
arg1Of |
end,that |
| R23746 |
T93319 |
T91466 |
arg1Of |
domains,helix |
| R23756 |
T89162 |
T17411 |
arg1Of |
as,a |
| R23783 |
T17751 |
T37324 |
arg2Of |
abundance,against |
| R23798 |
T61476 |
T61364 |
arg1Of |
residues,solvent-accessible |
| R238 |
T243 |
T244 |
arg1Of |
CoVs,represent |
| R2380 |
T70541 |
T91691 |
arg1Of |
and,how |
| R23813 |
T55283 |
T12200 |
arg1Of |
showed51,recently |
| R23849 |
T68539 |
T79414 |
arg1Of |
glycans,has |
| R23889 |
T79412 |
T67524 |
arg1Of |
is,in |
| R239 |
T247 |
T244 |
arg2Of |
threat,represent |
| R23954 |
T21302 |
T67673 |
arg1Of |
shields,glycan |
| R23985 |
T5164 |
T33108 |
arg1Of |
modelling,The |
| R240 |
T247 |
T245 |
arg1Of |
threat,a |
| R24020 |
T41479 |
T29326 |
arg1Of |
number,the |
| R24076 |
T43478 |
T18984 |
arg2Of |
Glu-C,"," |
| R241 |
T247 |
T246 |
arg1Of |
threat,significant |
| R2412 |
T3262 |
T95276 |
arg1Of |
glycoproteins,spike |
| R24149 |
T19203 |
T97210 |
arg1Of |
dataset,SARS |
| R242 |
T247 |
T248 |
arg1Of |
threat,to |
| R2421 |
T60437 |
T47078 |
arg2Of |
total,possesses |
| R2422 |
T4769 |
T7211 |
arg2Of |
Fig. 4b,( |
| R24220 |
T54076 |
T8587 |
arg1Of |
and,did |
| R24262 |
T55061 |
T4581 |
arg1Of |
cells,II |
| R24287 |
T12133 |
T34645 |
arg1Of |
5X58,"," |
| R243 |
T251 |
T248 |
arg2Of |
health,to |
| R24307 |
T17681 |
T15804 |
arg1Of |
candidates,elicit |
| R24318 |
T94206 |
T10071 |
arg1Of |
showed,However |
| R24334 |
T3264 |
T68472 |
modOf |
investigated,using |
| R24335 |
T11708 |
T68521 |
arg1Of |
5X58,PDB |
| R24338 |
T3894 |
T52698 |
arg1Of |
density,of |
| R24376 |
T56105 |
T47548 |
arg2Of |
derived,was |
| R244 |
T251 |
T249 |
arg1Of |
health,global |
| R24475 |
T45261 |
T77923 |
arg1Of |
rather,than |
| R245 |
T251 |
T250 |
arg1Of |
health,human |
| R2450 |
T69491 |
T17336 |
arg1Of |
estimates,are |
| R24535 |
T36749 |
T72350 |
modOf |
co-localize,consisting |
| R24547 |
T15066 |
T45711 |
arg2Of |
LC-MS,( |
| R24573 |
T19223 |
T67524 |
arg2Of |
comparison,in |
| R24584 |
T18714 |
T59290 |
arg2Of |
shield,and |
| R246 |
T244 |
T252 |
arg1Of |
represent,"," |
| R24616 |
T2961 |
T92960 |
arg1Of |
had,Likewise |
| R24628 |
T30499 |
T29305 |
modOf |
accessibility,to |
| R24648 |
T35120 |
T25962 |
arg1Of |
subjected,to |
| R24676 |
T24412 |
T69838 |
arg1Of |
limit,a |
| R24690 |
T54609 |
T71605 |
arg2Of |
glycans,of |
| R24697 |
T23755 |
T76280 |
arg1Of |
charts,pie |
| R247 |
T244 |
T253 |
arg1Of |
represent,as |
| R24751 |
T81231 |
T66257 |
arg1Of |
considered,in |
| R248 |
T254 |
T253 |
arg2Of |
illustrated,as |
| R24868 |
T93669 |
T73736 |
arg1Of |
compositions,glycan |
| R249 |
T256 |
T254 |
arg1Of |
outbreaks,illustrated |
| R24908 |
T90347 |
T57189 |
arg1Of |
proteins,S |
| R24936 |
T46208 |
T70071 |
arg1Of |
spikes,CoV |
| R24969 |
T14374 |
T39300 |
arg1Of |
graphs,afucosylated |
| R250 |
T256 |
T255 |
arg2Of |
outbreaks,by |
| R25095 |
T99370 |
T41135 |
modOf |
exhibits,resulting |
| R251 |
T256 |
T257 |
arg1Of |
outbreaks,of |
| R25119 |
T68729 |
T30100 |
arg1Of |
volume,of |
| R25157 |
T53051 |
T95730 |
arg1Of |
Env,( |
| R25166 |
T39921 |
T32276 |
arg1Of |
patterns,molecular |
| R25194 |
T19555 |
T65945 |
arg1Of |
importance,should |
| R252 |
T262 |
T257 |
arg2Of |
coronavirus,of |
| R25200 |
T38215 |
T76109 |
arg2Of |
rates,undergoing |
| R25217 |
T94871 |
T40910 |
arg2Of |
shield,through |
| R25260 |
T49864 |
T39300 |
arg2Of |
glycans,afucosylated |
| R253 |
T262 |
T258 |
arg1Of |
coronavirus,severe |
| R2531 |
T99373 |
T23895 |
arg1Of |
surfaces,white |
| R254 |
T262 |
T259 |
arg1Of |
coronavirus,acute |
| R25407 |
T9382 |
T94093 |
arg2Of |
S,and |
| R25467 |
T35915 |
T74928 |
arg2Of |
structure,on |
| R255 |
T262 |
T260 |
arg1Of |
coronavirus,respiratory |
| R25556 |
T34506 |
T66750 |
arg2Of |
with,compared |
| R25568 |
T63087 |
T60407 |
arg2Of |
S2,and |
| R25583 |
T41923 |
T21879 |
arg1Of |
11,S |
| R256 |
T262 |
T261 |
arg1Of |
coronavirus,syndrome |
| R2562 |
T68800 |
T18761 |
arg1Of |
",",and |
| R2567 |
T30499 |
T6499 |
arg2Of |
accessibility,hindered |
| R25678 |
T81728 |
T3044 |
arg1Of |
compared,on |
| R25685 |
T25884 |
T89591 |
arg2Of |
values,shown |
| R2569 |
T51449 |
T47768 |
arg1Of |
proteins,class |
| R257 |
T262 |
T263 |
arg1Of |
coronavirus,( |
| R25741 |
T53375 |
T27417 |
arg1Of |
95,% |
| R2577 |
T65868 |
T8410 |
arg2Of |
terms,in |
| R258 |
T264 |
T263 |
arg2Of |
SARS-CoV,( |
| R25857 |
T72291 |
T29813 |
arg2Of |
colored,are |
| R25874 |
T76185 |
T24421 |
arg1Of |
b,MERS |
| R25896 |
T44303 |
T81866 |
arg2Of |
diversity,of |
| R259 |
T265 |
T263 |
arg3Of |
),( |
| R260 |
T262 |
T266 |
arg1Of |
coronavirus,in |
| R26018 |
T27860 |
T18635 |
arg2Of |
events,repeated |
| R261 |
T267 |
T266 |
arg2Of |
20032,in |
| R26107 |
T18790 |
T25102 |
arg1Of |
glycans,occluded |
| R26115 |
T72393 |
T9777 |
arg2Of |
reprocessed,while |
| R26118 |
T28404 |
T28338 |
arg2Of |
S.,on |
| R26175 |
T94206 |
T88433 |
arg1Of |
showed,"," |
| R262 |
T256 |
T268 |
arg1Of |
outbreaks,"," |
| R263 |
T273 |
T268 |
arg2Of |
coronavirus,"," |
| R26332 |
T18104 |
T72056 |
arg2Of |
terms,in |
| R2636 |
T25304 |
T83245 |
arg1Of |
sequences,of |
| R26362 |
T55156 |
T45284 |
arg2Of |
vulnerabilities,revealing |
| R264 |
T270 |
T269 |
arg1Of |
East,Middle |
| R26419 |
T95596 |
T82828 |
arg2Of |
and,including |
| R26450 |
T25276 |
T97068 |
arg2Of |
glycans,of |
| R265 |
T273 |
T270 |
arg1Of |
coronavirus,East |
| R26511 |
T5302 |
T95555 |
arg1Of |
clusters,contribute |
| R26558 |
T80637 |
T26336 |
arg1Of |
S,HKU1 |
| R266 |
T273 |
T271 |
arg1Of |
coronavirus,respiratory |
| R26617 |
T53506 |
T84481 |
arg1Of |
is,topically |
| R267 |
T273 |
T272 |
arg1Of |
coronavirus,syndrome |
| R26701 |
T94405 |
T32515 |
arg1Of |
model,structural |
| R26733 |
T75209 |
T86558 |
arg2Of |
ectodomain52,of |
| R268 |
T273 |
T274 |
arg1Of |
coronavirus,( |
| R26875 |
T99830 |
T5062 |
arg2Of |
hindered,be |
| R26878 |
T73121 |
T7627 |
arg2Of |
whereas,suggest |
| R269 |
T275 |
T274 |
arg2Of |
MERS-CoV,( |
| R26921 |
T3759 |
T66405 |
arg1Of |
S,MERS |
| R26979 |
T77537 |
T76353 |
arg2Of |
shield,evolved |
| R26983 |
T3894 |
T23766 |
arg2Of |
density,reach |
| R26990 |
T65839 |
T13399 |
arg1Of |
and,the |
| R26999 |
T87387 |
T52944 |
arg2Of |
and,of |
| R270 |
T276 |
T274 |
arg3Of |
),( |
| R27001 |
T30776 |
T79009 |
arg1Of |
S,SARS |
| R27005 |
T74519 |
T95025 |
arg2Of |
glycans,of |
| R27037 |
T25276 |
T12761 |
arg1Of |
glycans,N-linked |
| R27056 |
T3180 |
T36644 |
arg1Of |
analysis,ascertained |
| R271 |
T273 |
T277 |
arg1Of |
coronavirus,in |
| R272 |
T278 |
T277 |
arg2Of |
20123,in |
| R27221 |
T81817 |
T32196 |
arg2Of |
order,In |
| R27231 |
T75541 |
T89745 |
arg2Of |
coronaviruses,on |
| R27251 |
T86628 |
T87992 |
arg1Of |
SARS,and |
| R27276 |
T93400 |
T38026 |
arg1Of |
N-linked,2 |
| R2728 |
T8652 |
T10460 |
arg2Of |
digested,and |
| R273 |
T280 |
T279 |
arg1Of |
and,"," |
| R27313 |
T65772 |
T12305 |
arg2Of |
abundance,and |
| R2734 |
T93568 |
T43920 |
arg1Of |
//nextstrain.org/ncov,) |
| R27361 |
T88747 |
T23330 |
arg2Of |
observed,has |
| R274 |
T277 |
T280 |
arg1Of |
in,and |
| R2740 |
T41175 |
T26594 |
arg1Of |
strong”56,had |
| R27405 |
T42803 |
T86408 |
arg2Of |
Fig. 3,in |
| R27432 |
T59672 |
T60387 |
arg2Of |
considered,and |
| R27443 |
T22579 |
T69920 |
arg1Of |
with,along |
| R27480 |
T39562 |
T69974 |
arg1Of |
b,variability |
| R275 |
T283 |
T280 |
arg2Of |
of,and |
| R27517 |
T72195 |
T78182 |
arg1Of |
recognition,of |
| R27546 |
T33045 |
T4038 |
arg1Of |
quantification,the |
| R27562 |
T91138 |
T57479 |
arg2Of |
residues,of |
| R27590 |
T70221 |
T54076 |
arg2Of |
proteins,and |
| R276 |
T282 |
T281 |
arg1Of |
recently,most |
| R27660 |
T24985 |
T40354 |
arg2Of |
that,found |
| R27680 |
T54985 |
T71503 |
arg1Of |
proteins,are |
| R277 |
T283 |
T282 |
arg1Of |
of,recently |
| R27719 |
T29760 |
T28968 |
arg1Of |
repeat,heptad |
| R27746 |
T67026 |
T89902 |
arg1Of |
domains,S1 |
| R27785 |
T97014 |
T85837 |
arg1Of |
response,in |
| R278 |
T273 |
T283 |
arg1Of |
coronavirus,of |
| R27836 |
T40276 |
T29532 |
arg2Of |
found,can |
| R2785 |
T9629 |
T60926 |
arg1Of |
and,were |
| R279 |
T284 |
T283 |
arg2Of |
SARS-CoV-24,of |
| R27910 |
T72051 |
T20968 |
arg2Of |
populations,and |
| R27911 |
T33026 |
T45752 |
arg1Of |
glycans,were |
| R27919 |
T24762 |
T43495 |
arg2Of |
glycoprotein,of |
| R27948 |
T30294 |
T78773 |
arg1Of |
densities,were |
| R27975 |
T50573 |
T62342 |
arg1Of |
and,respectively |
| R280 |
T313 |
T285 |
arg1Of |
is,Given |
| R28008 |
T40780 |
T31749 |
arg1Of |
clusters,specific |
| R28028 |
T70036 |
T3633 |
arg2Of |
pink,( |
| R28079 |
T65417 |
T4164 |
arg2Of |
differ,may |
| R281 |
T300 |
T285 |
arg2Of |
and,Given |
| R28101 |
T60190 |
T33888 |
arg2Of |
Fig. 4c,( |
| R28106 |
T56273 |
T90429 |
arg1Of |
map,3.2-Å-resolution |
| R282 |
T288 |
T286 |
arg1Of |
rates,their |
| R28202 |
T99530 |
T71906 |
arg1Of |
analysis,N-linked |
| R28264 |
T46492 |
T66630 |
arg1Of |
and,be |
| R283 |
T288 |
T287 |
arg1Of |
rates,mortality |
| R28302 |
T11057 |
T44946 |
arg1Of |
analysis,and |
| R28308 |
T5302 |
T66164 |
arg1Of |
clusters,mannose |
| R28323 |
T65408 |
T21150 |
arg2Of |
dividing,by |
| R28324 |
T67621 |
T30037 |
arg1Of |
hand,the |
| R28363 |
T83312 |
T51718 |
arg1Of |
construct,( |
| R28386 |
T46492 |
T99241 |
arg2Of |
and,with |
| R284 |
T288 |
T289 |
arg1Of |
rates,"," |
| R2842 |
T99530 |
T84409 |
arg1Of |
analysis,site-specific |
| R28422 |
T36278 |
T63214 |
arg1Of |
S,SARS |
| R28428 |
T15412 |
T38048 |
arg1Of |
domains,of |
| R28443 |
T3483 |
T73202 |
arg1Of |
performed,To |
| R28444 |
T5930 |
T81500 |
arg1Of |
infectivity,viral |
| R28497 |
T40686 |
T79396 |
arg2Of |
produce,fail |
| R285 |
T292 |
T289 |
arg2Of |
lack,"," |
| R28527 |
T93319 |
T49934 |
arg1Of |
domains,which |
| R28543 |
T44450 |
T36665 |
arg1Of |
coronaviruses,MERS |
| R286 |
T292 |
T290 |
arg1Of |
lack,the |
| R2862 |
T95304 |
T69427 |
arg3Of |
),( |
| R28655 |
T89313 |
T11621 |
arg2Of |
much,offer |
| R28693 |
T16112 |
T17730 |
arg1Of |
diversification,across |
| R287 |
T292 |
T291 |
arg1Of |
lack,current |
| R28704 |
T77822 |
T51235 |
arg2Of |
"glycoprotein22,58",upon |
| R28712 |
T57392 |
T14064 |
arg1Of |
information,compositional |
| R2872 |
T21302 |
T58960 |
arg1Of |
shields,Env |
| R28786 |
T94035 |
T44190 |
arg1Of |
and,) |
| R288 |
T292 |
T293 |
arg1Of |
lack,of |
| R28846 |
T74716 |
T24648 |
arg1Of |
is,that |
| R289 |
T296 |
T293 |
arg2Of |
and,of |
| R28915 |
T83454 |
T98572 |
arg2Of |
pathogens,of |
| R28975 |
T3337 |
T69159 |
arg1Of |
shield51,glycan |
| R290 |
T295 |
T294 |
arg2Of |
treatments,targeted |
| R291 |
T295 |
T296 |
arg1Of |
treatments,and |
| R29152 |
T47095 |
T76573 |
arg1Of |
reduced,"," |
| R29198 |
T39676 |
T22591 |
arg2Of |
"vivo57,58",in |
| R292 |
T298 |
T296 |
arg2Of |
vaccines,and |
| R29213 |
T38040 |
T6796 |
arg1Of |
structure,the |
| R29286 |
T46492 |
T48178 |
arg1Of |
and,"," |
| R293 |
T298 |
T297 |
arg1Of |
vaccines,licensed |
| R29301 |
T52822 |
T91723 |
arg1Of |
visualize,to |
| R29324 |
T12133 |
T35725 |
arg1Of |
5X58,PDB |
| R2936 |
T17551 |
T33530 |
arg2Of |
shields,of |
| R29363 |
T93961 |
T6760 |
arg1Of |
colored,"," |
| R29370 |
T73192 |
T18164 |
arg1Of |
result,from |
| R294 |
T300 |
T299 |
arg1Of |
and,"," |
| R29477 |
T73192 |
T1176 |
arg2Of |
result,may |
| R295 |
T289 |
T300 |
arg1Of |
",",and |
| R296 |
T302 |
T300 |
arg2Of |
capacity,and |
| R29627 |
T61005 |
T62312 |
arg1Of |
Env,( |
| R2968 |
T28847 |
T5339 |
arg2Of |
red,in |
| R29694 |
T28812 |
T23330 |
arg1Of |
phenomenon,has |
| R297 |
T302 |
T301 |
arg1Of |
capacity,their |
| R29757 |
T10724 |
T29355 |
arg1Of |
leading,to |
| R2979 |
T14194 |
T85081 |
arg2Of |
glycosylation,of |
| R298 |
T304 |
T303 |
arg1Of |
transmit,to |
| R29816 |
T4404 |
T10224 |
arg1Of |
and,MERS |
| R29835 |
T12587 |
T66257 |
arg2Of |
environment,in |
| R29839 |
T44453 |
T83252 |
arg1Of |
densities,shield |
| R299 |
T302 |
T303 |
modOf |
capacity,to |
| R29921 |
T95071 |
T21278 |
arg2Of |
observed,was |
| R2996 |
T16112 |
T79527 |
arg1Of |
diversification,sequence |
| R29975 |
T32151 |
T95784 |
arg1Of |
arises,that |
| R29976 |
T36486 |
T66534 |
arg2Of |
all,with |
| R29978 |
T40276 |
T93684 |
arg2Of |
found,be |
| R300 |
T304 |
T305 |
arg1Of |
transmit,between |
| R3001 |
T29000 |
T79412 |
arg2Of |
sparser,is |
| R30047 |
T28741 |
T76185 |
arg1Of |
mapping,b |
| R30085 |
T63997 |
T41377 |
arg2Of |
example,for |
| R301 |
T306 |
T305 |
arg2Of |
humans,between |
| R30100 |
T15412 |
T76133 |
arg1Of |
domains,the |
| R30154 |
T66339 |
T16555 |
arg3Of |
incapable,render |
| R30159 |
T32151 |
T86749 |
arg1Of |
arises,to |
| R30163 |
T16458 |
T63581 |
arg1Of |
dataset52,2P |
| R30172 |
T33026 |
T44762 |
arg2Of |
glycans,labelled |
| R30180 |
T76860 |
T12192 |
arg2Of |
glycans,presented |
| R302 |
T285 |
T307 |
arg1Of |
Given,and |
| R303 |
T308 |
T307 |
arg2Of |
across,and |
| R30304 |
T55016 |
T30445 |
arg2Of |
with,compared |
| R30322 |
T31709 |
T36472 |
arg1Of |
structure,the |
| R3033 |
T26975 |
T64977 |
arg1Of |
network,of |
| R30349 |
T68442 |
T34000 |
arg1Of |
domains,receptor-binding |
| R30385 |
T6494 |
T65600 |
arg1Of |
sites,receptor-binding |
| R304 |
T313 |
T308 |
arg1Of |
is,across |
| R30400 |
T69312 |
T85163 |
arg1Of |
and,"," |
| R30471 |
T1374 |
T1375 |
arg1Of |
study,adds |
| R30496 |
T27945 |
T75621 |
arg1Of |
residues,interacting |
| R305 |
T310 |
T308 |
arg2Of |
"barriers5,6",across |
| R30503 |
T19203 |
T69700 |
arg1Of |
dataset,the |
| R30561 |
T84994 |
T28395 |
arg2Of |
processing,observed |
| R30596 |
T12587 |
T94028 |
arg1Of |
environment,which |
| R306 |
T310 |
T309 |
arg1Of |
"barriers5,6",species |
| R30633 |
T81925 |
T15094 |
arg1Of |
proteins,( |
| R30657 |
T74716 |
T1822 |
arg1Of |
is,is |
| R307 |
T313 |
T311 |
arg1Of |
is,"," |
| R30712 |
T10045 |
T39650 |
arg2Of |
known,( |
| R308 |
T312 |
T313 |
arg1Of |
there,is |
| R30852 |
T4934 |
T42560 |
arg1Of |
responses,immune |
| R309 |
T316 |
T313 |
arg2Of |
need,is |
| R3093 |
T88004 |
T70835 |
arg1Of |
mutants,these |
| R30949 |
T96908 |
T54010 |
arg1Of |
based,on |
| R30995 |
T10009 |
T62759 |
arg1Of |
studied,and |
| R30996 |
T16085 |
T2441 |
arg2Of |
resolutions,at |
| R310 |
T316 |
T314 |
arg1Of |
need,an |
| R31060 |
T79807 |
T17443 |
arg2Of |
Fig. 3a,( |
| R3107 |
T99472 |
T4874 |
arg1Of |
constraints,greater |
| R311 |
T316 |
T315 |
arg1Of |
need,urgent |
| R31129 |
T55408 |
T8471 |
arg2Of |
ratio,calculated |
| R31141 |
T77922 |
T36749 |
arg1Of |
glycans,co-localize |
| R31178 |
T59031 |
T50530 |
arg1Of |
glycans,lack |
| R312 |
T316 |
T317 |
arg1Of |
need,for |
| R31235 |
T2487 |
T10413 |
arg2Of |
auto-thresholding,and |
| R31243 |
T34676 |
T27307 |
arg2Of |
be,may |
| R31252 |
T70902 |
T80278 |
arg1Of |
plays,in |
| R31263 |
T50640 |
T20053 |
arg1Of |
and,"," |
| R31284 |
T26533 |
T86435 |
arg1Of |
a,) |
| R313 |
T319 |
T317 |
arg2Of |
countermeasures,for |
| R31305 |
T13006 |
T17100 |
arg1Of |
sites,with |
| R3135 |
T62826 |
T75452 |
arg2Of |
Fig. 2a,( |
| R314 |
T321 |
T317 |
arg3Of |
combat,for |
| R3140 |
T38777 |
T3264 |
arg2Of |
densities,investigated |
| R31488 |
T59672 |
T67170 |
arg1Of |
considered,in |
| R315 |
T319 |
T318 |
arg1Of |
countermeasures,effective |
| R31526 |
T2204 |
T70578 |
arg1Of |
sites,of |
| R31579 |
T72666 |
T60433 |
arg2Of |
approach,calculated |
| R31581 |
T27072 |
T6464 |
arg2Of |
Env49,"," |
| R316 |
T321 |
T320 |
arg1Of |
combat,to |
| R31607 |
T58379 |
T53325 |
arg1Of |
target,of |
| R31614 |
T1949 |
T35196 |
arg2Of |
diversity,shown |
| R31615 |
T77922 |
T49774 |
arg1Of |
glycans,oligomannose-type |
| R31642 |
T99472 |
T34520 |
arg1Of |
constraints,( |
| R31693 |
T70745 |
T15216 |
arg1Of |
families,viral |
| R31695 |
T48265 |
T55384 |
arg1Of |
quantities,with |
| R317 |
T319 |
T321 |
arg1Of |
countermeasures,combat |
| R31717 |
T46492 |
T59110 |
arg1Of |
and,which |
| R31766 |
T40473 |
T20923 |
arg1Of |
according,to |
| R318 |
T323 |
T321 |
arg2Of |
pathogens,combat |
| R31827 |
T46492 |
T61432 |
arg1Of |
and,are |
| R31883 |
T58379 |
T7334 |
arg1Of |
target,"," |
| R319 |
T323 |
T322 |
arg1Of |
pathogens,these |
| R31934 |
T28342 |
T24257 |
arg1Of |
and,their |
| R31936 |
T80158 |
T18287 |
arg1Of |
SI,Fig. 2 |
| R320 |
T328 |
T324 |
arg1Of |
focus,Ongoing |
| R32000 |
T70981 |
T19767 |
arg1Of |
due,likely |
| R32001 |
T94871 |
T14483 |
arg1Of |
shield,the |
| R32032 |
T23375 |
T30414 |
arg3Of |
),( |
| R32039 |
T17551 |
T16798 |
arg1Of |
shields,of |
| R32077 |
T14190 |
T99213 |
arg1Of |
analysis,variability |
| R321 |
T328 |
T325 |
arg1Of |
focus,vaccine |
| R32137 |
T16085 |
T86172 |
arg1Of |
resolutions,necessary |
| R32141 |
T3894 |
T96858 |
arg1Of |
density,the |
| R322 |
T328 |
T326 |
arg1Of |
focus,development |
| R32231 |
T82055 |
T99485 |
arg1Of |
as,such |
| R32297 |
T75554 |
T16555 |
arg1Of |
spikes,render |
| R323 |
T328 |
T327 |
arg1Of |
focus,efforts |
| R32364 |
T82951 |
T81018 |
arg2Of |
hallmark,are |
| R324 |
T328 |
T329 |
arg1Of |
focus,on |
| R32448 |
T97839 |
T87216 |
arg1Of |
note,It |
| R32451 |
T64807 |
T1909 |
arg2Of |
hemagglutinin,"," |
| R3248 |
T64331 |
T46802 |
arg1Of |
ratios,dN/dS |
| R32496 |
T17751 |
T83132 |
arg1Of |
abundance,oligomannose |
| R325 |
T335 |
T329 |
arg2Of |
proteins,on |
| R32590 |
T43748 |
T3599 |
arg1Of |
structure,atomic |
| R32592 |
T11220 |
T73691 |
arg2Of |
dynamics,and |
| R326 |
T335 |
T330 |
arg1Of |
proteins,the |
| R32632 |
T12305 |
T26594 |
arg2Of |
and,had |
| R327 |
T335 |
T331 |
arg1Of |
proteins,spike |
| R32729 |
T69246 |
T66095 |
arg1Of |
domain,the |
| R328 |
T335 |
T332 |
arg1Of |
proteins,( |
| R3285 |
T3180 |
T73246 |
arg2Of |
analysis,by |
| R3287 |
T69246 |
T52990 |
arg1Of |
domain,S2 |
| R329 |
T333 |
T332 |
arg2Of |
S,( |
| R32904 |
T69826 |
T57750 |
arg2Of |
glycoprotein,of |
| R32959 |
T84481 |
T92680 |
arg1Of |
topically,More |
| R330 |
T334 |
T332 |
arg3Of |
),( |
| R33015 |
T14141 |
T95025 |
arg1Of |
presence,of |
| R33056 |
T77922 |
T72350 |
arg1Of |
glycans,consisting |
| R33083 |
T37715 |
T31650 |
arg1Of |
et,Berndsen |
| R331 |
T335 |
T336 |
arg1Of |
proteins,that |
| R33103 |
T38040 |
T51236 |
arg1Of |
structure,of |
| R33105 |
T41479 |
T1834 |
arg1Of |
number,of |
| R33143 |
T5302 |
T65310 |
arg1Of |
clusters,that |
| R33151 |
T90138 |
T79086 |
arg1Of |
SARS,( |
| R332 |
T335 |
T337 |
arg1Of |
proteins,protrude |
| R3329 |
T57392 |
T40276 |
arg2Of |
information,found |
| R333 |
T337 |
T338 |
arg1Of |
protrude,from |
| R33306 |
T94093 |
T63910 |
arg1Of |
and,( |
| R33310 |
T26306 |
T89403 |
arg1Of |
we,used |
| R3336 |
T74546 |
T60387 |
arg1Of |
investigated,and |
| R3337 |
T26380 |
T92544 |
arg1Of |
value,of |
| R33373 |
T78348 |
T49839 |
arg2Of |
Fig. 5,( |
| R334 |
T341 |
T338 |
arg2Of |
envelope,from |
| R33403 |
T81512 |
T33229 |
arg1Of |
18,being |
| R33406 |
T35201 |
T47385 |
arg1Of |
reflected,further |
| R33443 |
T45372 |
T66305 |
arg2Of |
tempting,is |
| R335 |
T341 |
T339 |
arg1Of |
envelope,the |
| R33550 |
T79346 |
T99997 |
arg1Of |
route,to |
| R33554 |
T64543 |
T98572 |
arg1Of |
zoonosis,of |
| R33595 |
T97427 |
T11359 |
arg1Of |
and,consist |
| R336 |
T341 |
T340 |
arg1Of |
envelope,viral |
| R33651 |
T39562 |
T5294 |
arg2Of |
b,: |
| R33652 |
T7451 |
T93687 |
arg1Of |
",","," |
| R33694 |
T83803 |
T3618 |
arg1Of |
M9,to |
| R337 |
T337 |
T342 |
arg1Of |
protrude,and |
| R33706 |
T39921 |
T72183 |
arg1Of |
patterns,pathogen-associated |
| R33721 |
T48779 |
T3547 |
arg1Of |
indicated,"," |
| R33747 |
T46887 |
T52910 |
arg2Of |
sites,and |
| R33779 |
T40590 |
T30498 |
arg1Of |
area,protein |
| R338 |
T343 |
T342 |
arg2Of |
constitute,and |
| R33832 |
T24905 |
T58957 |
arg1Of |
area,surface |
| R339 |
T335 |
T343 |
arg1Of |
proteins,constitute |
| R33985 |
T26472 |
T22974 |
arg1Of |
subunit,S2 |
| R33999 |
T14860 |
T75452 |
arg3Of |
),( |
| R340 |
T346 |
T343 |
arg2Of |
target,constitute |
| R34019 |
T17113 |
T93138 |
arg2Of |
proteins,digested |
| R34068 |
T81576 |
T15304 |
arg2Of |
underprocessed,were |
| R341 |
T346 |
T344 |
arg1Of |
target,the |
| R34126 |
T61867 |
T97427 |
arg1Of |
GPC,and |
| R34127 |
T93291 |
T40028 |
arg1Of |
filtering,low-pass |
| R34151 |
T29035 |
T30617 |
arg1Of |
Comparison,between |
| R34175 |
T24421 |
T8210 |
arg1Of |
MERS,a |
| R34180 |
T30499 |
T19511 |
arg1Of |
accessibility,the |
| R34184 |
T53545 |
T94530 |
arg1Of |
enzymes,processing |
| R3419 |
T85948 |
T93438 |
arg2Of |
perturbing,without |
| R342 |
T346 |
T345 |
arg1Of |
target,main |
| R34223 |
T27616 |
T47642 |
arg2Of |
Fig. 5,( |
| R34224 |
T16555 |
T68142 |
arg2Of |
render,would |
| R34277 |
T33026 |
T60951 |
arg1Of |
glycans,that |
| R34279 |
T59603 |
T86795 |
arg1Of |
values,dN/dS |
| R34285 |
T23338 |
T95596 |
arg2Of |
HA50,and |
| R3429 |
T11435 |
T47037 |
arg1Of |
advantage,protective |
| R343 |
T346 |
T347 |
arg1Of |
target,of |
| R3433 |
T94405 |
T45778 |
arg2Of |
model,onto |
| R34352 |
T51710 |
T95596 |
arg1Of |
",",and |
| R34359 |
T44348 |
T84029 |
arg2Of |
MERS,Purified |
| R34390 |
T39713 |
T81231 |
arg2Of |
they,considered |
| R344 |
T348 |
T347 |
arg2Of |
neutralizing,of |
| R34457 |
T28784 |
T68425 |
arg1Of |
5X59,PDB |
| R345 |
T349 |
T348 |
arg2Of |
"antibodies7,8",neutralizing |
| R34518 |
T48265 |
T51798 |
arg1Of |
quantities,( |
| R34568 |
T69499 |
T65163 |
arg1Of |
Analysis,of |
| R34571 |
T9415 |
T91463 |
arg1Of |
variability,coming |
| R34585 |
T35201 |
T57766 |
arg1Of |
reflected,"," |
| R346 |
T353 |
T350 |
arg1Of |
proteins,These |
| R34633 |
T41472 |
T24446 |
arg2Of |
glycosylation,of |
| R34682 |
T68424 |
T79801 |
arg1Of |
We,ascertain |
| R347 |
T353 |
T351 |
arg1Of |
proteins,trimeric |
| R34726 |
T72037 |
T19959 |
arg1Of |
most,remaining |
| R3479 |
T54092 |
T2107 |
arg2Of |
right,to |
| R348 |
T353 |
T352 |
arg1Of |
proteins,S |
| R34840 |
T71146 |
T5339 |
arg1Of |
colored,in |
| R34853 |
T86863 |
T73114 |
arg2Of |
viruses,compare |
| R34860 |
T25542 |
T55713 |
arg1Of |
coverage,of |
| R34869 |
T37597 |
T19064 |
arg1Of |
data,HIV |
| R34883 |
T10053 |
T55394 |
arg1Of |
speculate,"," |
| R349 |
T353 |
T354 |
arg1Of |
proteins,mediate |
| R34905 |
T4586 |
T35591 |
arg2Of |
0.31,of |
| R34919 |
T1949 |
T70132 |
arg1Of |
diversity,amino-acid |
| R34991 |
T44352 |
T3158 |
arg1Of |
shielding,glycan |
| R34998 |
T74519 |
T70586 |
arg1Of |
glycans,oligomannose-type |
| R350 |
T356 |
T354 |
arg2Of |
entry,mediate |
| R35005 |
T19047 |
T77710 |
arg1Of |
analysis,Fig. |
| R35026 |
T51996 |
T60493 |
modOf |
calculated,using |
| R35049 |
T42677 |
T43754 |
arg1Of |
distribution,of |
| R35059 |
T87308 |
T48330 |
arg1Of |
all-encompassing,nearly |
| R35082 |
T82870 |
T78718 |
arg1Of |
protein,S |
| R351 |
T356 |
T355 |
arg1Of |
entry,host-cell |
| R3511 |
T19879 |
T80173 |
arg1Of |
",","," |
| R35116 |
T77577 |
T22099 |
arg2Of |
observed,are |
| R35155 |
T92070 |
T31354 |
arg1Of |
proteins,S |
| R352 |
T354 |
T357 |
arg1Of |
mediate,with |
| R35270 |
T95495 |
T28888 |
arg1Of |
grey,light |
| R353 |
T362 |
T357 |
arg2Of |
subunits,with |
| R35366 |
T66804 |
T90175 |
arg1Of |
surface,protein |
| R35368 |
T75995 |
T94718 |
arg2Of |
observed,as |
| R35379 |
T95927 |
T91547 |
arg1Of |
fucosylation,core |
| R354 |
T362 |
T358 |
arg1Of |
subunits,the |
| R35402 |
T11621 |
T26368 |
arg2Of |
offer,since |
| R35456 |
T72666 |
T75361 |
arg1Of |
approach,was |
| R35471 |
T65942 |
T28802 |
arg1Of |
Fabs51,base-specific |
| R35479 |
T32151 |
T60015 |
arg2Of |
arises,hypothesized |
| R355 |
T362 |
T359 |
arg1Of |
subunits,S1 |
| R356 |
T359 |
T360 |
arg1Of |
S1,and |
| R35607 |
T93380 |
T1991 |
arg1Of |
and,"," |
| R35610 |
T13277 |
T38634 |
arg1Of |
all,of |
| R3563 |
T54786 |
T50741 |
arg1Of |
"research22,60",vaccine |
| R35674 |
T41135 |
T24089 |
modOf |
resulting,to |
| R35680 |
T93669 |
T41991 |
arg1Of |
compositions,experimentally |
| R357 |
T361 |
T360 |
arg2Of |
S2,and |
| R35700 |
T94857 |
T80900 |
arg1Of |
Mapping,mean |
| R35754 |
T79227 |
T13208 |
arg2Of |
Asn166,"," |
| R35795 |
T43286 |
T32529 |
arg2Of |
penetrate,could |
| R35799 |
T61369 |
T78947 |
arg1Of |
ratio,relative |
| R358 |
T362 |
T361 |
arg1Of |
subunits,S2 |
| R35841 |
T77577 |
T53841 |
arg1Of |
observed,while |
| R359 |
T362 |
T363 |
arg1Of |
subunits,responsible |
| R35928 |
T38470 |
T82290 |
arg2Of |
SARS,and |
| R360 |
T363 |
T364 |
arg1Of |
responsible,for |
| R36002 |
T85214 |
T73775 |
arg2Of |
and,of |
| R36011 |
T17681 |
T53332 |
arg1Of |
candidates,able |
| R36037 |
T49843 |
T8574 |
arg2Of |
hotspots,highlighted |
| R3609 |
T40721 |
T4786 |
arg1Of |
panel,Middle |
| R361 |
T370 |
T364 |
arg2Of |
and,for |
| R36115 |
T54724 |
T45778 |
arg1Of |
mapped,onto |
| R36125 |
T27706 |
T12646 |
arg1Of |
and,of |
| R36158 |
T80500 |
T2961 |
arg1Of |
residues,had |
| R3618 |
T73857 |
T52453 |
arg1Of |
convolved,with |
| R3619 |
T88367 |
T55071 |
arg2Of |
levels,revealed |
| R362 |
T365 |
T366 |
arg1Of |
binding,to |
| R36201 |
T5495 |
T12106 |
arg1Of |
mutations,N236A |
| R3623 |
T43073 |
T72481 |
arg1Of |
overlaid,peptide-only |
| R36276 |
T45067 |
T38496 |
arg1Of |
glycans,shield |
| R363 |
T369 |
T366 |
arg2Of |
receptor,to |
| R36325 |
T64129 |
T13582 |
arg1Of |
MERS,and |
| R364 |
T369 |
T367 |
arg1Of |
receptor,the |
| R36430 |
T48779 |
T34630 |
arg2Of |
indicated,are |
| R3644 |
T61150 |
T75194 |
arg2Of |
A1,( |
| R36469 |
T12886 |
T64492 |
arg1Of |
N155A,"," |
| R365 |
T369 |
T368 |
arg1Of |
receptor,host-cell |
| R366 |
T365 |
T370 |
arg1Of |
binding,and |
| R36620 |
T46357 |
T91746 |
arg1Of |
differences,pairwise |
| R36627 |
T70460 |
T12473 |
arg2Of |
clustering,reduced |
| R367 |
T371 |
T370 |
arg2Of |
facilitating,and |
| R36741 |
T17810 |
T23843 |
arg2Of |
responses,of |
| R36773 |
T65168 |
T77097 |
arg2Of |
content,to |
| R368 |
T373 |
T371 |
arg2Of |
fusion,facilitating |
| R36808 |
T99370 |
T34922 |
arg1Of |
exhibits,"," |
| R36824 |
T66804 |
T95551 |
arg2Of |
surface,buried |
| R36844 |
T87940 |
T87134 |
arg2Of |
and,in |
| R36848 |
T57983 |
T16903 |
arg2Of |
"shield54,55",of |
| R36854 |
T29035 |
T92542 |
arg1Of |
Comparison,of |
| R36891 |
T20594 |
T39672 |
arg1Of |
residues,amino-acid |
| R369 |
T373 |
T372 |
arg1Of |
fusion,membrane |
| R36912 |
T74921 |
T20774 |
arg1Of |
panel,Right |
| R36961 |
T93591 |
T35302 |
arg2Of |
elevated,was |
| R36990 |
T43156 |
T94719 |
arg1Of |
intervals,density |
| R370 |
T362 |
T374 |
arg1Of |
subunits,"," |
| R37036 |
T34676 |
T64649 |
arg1Of |
be,In |
| R37081 |
T25102 |
T46892 |
arg2Of |
occluded,are |
| R37083 |
T92849 |
T90969 |
arg2Of |
residues,Buried |
| R371 |
T375 |
T374 |
arg2Of |
respectively9–11,"," |
| R3711 |
T79028 |
T29305 |
arg1Of |
access,to |
| R37191 |
T67976 |
T37828 |
arg1Of |
glycome,the |
| R372 |
T377 |
T376 |
arg1Of |
S,MERS |
| R37258 |
T62735 |
T33520 |
arg2Of |
and,of |
| R373 |
T377 |
T378 |
arg1Of |
S,binds |
| R374 |
T378 |
T379 |
arg1Of |
binds,to |
| R37429 |
T93669 |
T17443 |
arg1Of |
compositions,( |
| R37437 |
T87051 |
T66339 |
arg1Of |
it,incapable |
| R37446 |
T49759 |
T13436 |
arg1Of |
are,but |
| R37452 |
T36034 |
T78152 |
arg1Of |
epitopes,immunogenic |
| R375 |
T380 |
T379 |
arg2Of |
dipeptidyl-peptidase,to |
| R37505 |
T13185 |
T50573 |
arg1Of |
n = 70,and |
| R37534 |
T39465 |
T63649 |
arg1Of |
“shields”,of |
| R37559 |
T13006 |
T68681 |
arg2Of |
sites,knock |
| R37586 |
T77537 |
T85678 |
arg1Of |
shield,dense |
| R37591 |
T67259 |
T56277 |
arg2Of |
on,depending |
| R376 |
T380 |
T381 |
arg1Of |
dipeptidyl-peptidase,4 |
| R37616 |
T64664 |
T93568 |
arg1Of |
revealed,//nextstrain.org/ncov |
| R37654 |
T98451 |
T54724 |
arg2Of |
diversities,mapped |
| R377 |
T380 |
T382 |
arg1Of |
dipeptidyl-peptidase,( |
| R378 |
T383 |
T382 |
arg2Of |
DPP4,( |
| R3781 |
T33615 |
T87940 |
arg1Of |
SARS,and |
| R37843 |
T18714 |
T10675 |
arg1Of |
shield,glycan |
| R37889 |
T73121 |
T31775 |
arg1Of |
whereas,"," |
| R379 |
T384 |
T382 |
arg3Of |
),( |
| R37988 |
T49812 |
T18669 |
arg1Of |
particles,virus-like |
| R380 |
T380 |
T385 |
arg1Of |
dipeptidyl-peptidase,12 |
| R38048 |
T43420 |
T18725 |
arg1Of |
and,"," |
| R38059 |
T71311 |
T20923 |
arg2Of |
number,to |
| R38078 |
T97769 |
T37387 |
arg2Of |
nextstrain61,from |
| R38082 |
T1963 |
T32823 |
arg1Of |
implicated,also |
| R381 |
T378 |
T386 |
arg1Of |
binds,"," |
| R38109 |
T13438 |
T3618 |
arg2Of |
M5,to |
| R38141 |
T60681 |
T9810 |
arg1Of |
diversification,Sequence |
| R38169 |
T69877 |
T70780 |
arg1Of |
trimers,in |
| R382 |
T378 |
T387 |
arg1Of |
binds,whereas |
| R38262 |
T23755 |
T57945 |
arg1Of |
charts,summarise |
| R38291 |
T87051 |
T16555 |
arg2Of |
it,render |
| R383 |
T392 |
T387 |
arg2Of |
utilize,whereas |
| R38316 |
T77800 |
T78537 |
arg1Of |
analysis,of |
| R38335 |
T84041 |
T37933 |
arg1Of |
Fig. 6,and |
| R3838 |
T27706 |
T36859 |
arg2Of |
and,of |
| R384 |
T389 |
T388 |
arg1Of |
S13,SARS |
| R38415 |
T40590 |
T87161 |
arg1Of |
area,surface |
| R38420 |
T15044 |
T97054 |
arg1Of |
and,which |
| R38434 |
T62928 |
T13983 |
arg1Of |
glycans,arise |
| R3845 |
T31999 |
T60493 |
arg2Of |
and,using |
| R38468 |
T24930 |
T61347 |
arg1Of |
S,SARS |
| R385 |
T389 |
T390 |
arg1Of |
S13,and |
| R38518 |
T80657 |
T49427 |
arg1Of |
protein,fusion |
| R38554 |
T48779 |
T13712 |
arg1Of |
indicated,respectively |
| R3858 |
T18984 |
T82693 |
arg1Of |
",",and |
| R3859 |
T48129 |
T41593 |
arg2Of |
IgG,of |
| R386 |
T391 |
T390 |
arg2Of |
"SARS-CoV-214,15",and |
| R38610 |
T21412 |
T37324 |
arg1Of |
plotted,against |
| R38629 |
T77097 |
T72784 |
arg2Of |
to,according |
| R38632 |
T92849 |
T78244 |
arg1Of |
residues,on |
| R38659 |
T89162 |
T30415 |
arg1Of |
as,compare |
| R38678 |
T77710 |
T43639 |
arg1Of |
Fig.,5 |
| R387 |
T390 |
T392 |
arg1Of |
and,utilize |
| R38765 |
T30294 |
T57548 |
arg1Of |
densities,Glycan |
| R388 |
T394 |
T392 |
arg2Of |
enzyme,utilize |
| R38837 |
T32345 |
T48983 |
arg1Of |
environment,immune |
| R38877 |
T34676 |
T78686 |
arg1Of |
be,"," |
| R389 |
T394 |
T393 |
arg1Of |
enzyme,angiotensin-converting |
| R38925 |
T18714 |
T87196 |
arg1Of |
shield,"," |
| R38960 |
T70981 |
T56477 |
arg2Of |
due,is |
| R390 |
T394 |
T395 |
arg1Of |
enzyme,2 |
| R39024 |
T71248 |
T33142 |
arg1Of |
expressed,as |
| R39068 |
T77577 |
T14875 |
arg1Of |
observed,"," |
| R391 |
T394 |
T396 |
arg1Of |
enzyme,( |
| R3910 |
T79801 |
T45093 |
arg1Of |
ascertain,to |
| R39154 |
T40508 |
T85817 |
arg1Of |
sites,receptor-binding |
| R39194 |
T14374 |
T64768 |
arg1Of |
graphs,represent |
| R39195 |
T28784 |
T78652 |
arg2Of |
5X59,( |
| R392 |
T397 |
T396 |
arg2Of |
ACE2,( |
| R39207 |
T53545 |
T56293 |
arg2Of |
enzymes,of |
| R39260 |
T75718 |
T58946 |
arg1Of |
mapping,Structure-based |
| R393 |
T398 |
T396 |
arg3Of |
),( |
| R39310 |
T40406 |
T5519 |
arg2Of |
and,as |
| R39332 |
T84994 |
T58559 |
arg2Of |
processing,to |
| R39369 |
T72197 |
T73801 |
arg1Of |
glycoproteins,these |
| R39372 |
T43288 |
T27968 |
arg2Of |
resides,for |
| R39386 |
T65417 |
T91973 |
arg2Of |
differ,but |
| R394 |
T392 |
T399 |
arg1Of |
utilize,as |
| R395 |
T403 |
T399 |
arg2Of |
receptor,as |
| R39529 |
T76353 |
T32869 |
arg1Of |
evolved,that |
| R39589 |
T98975 |
T51805 |
arg1Of |
majority,the |
| R396 |
T403 |
T400 |
arg1Of |
receptor,a |
| R39691 |
T12725 |
T53426 |
arg1Of |
divided,as |
| R397 |
T403 |
T401 |
arg1Of |
receptor,host |
| R39709 |
T81231 |
T83434 |
arg2Of |
considered,be |
| R39712 |
T12013 |
T79243 |
arg2Of |
HKU1,and |
| R39745 |
T80993 |
T91843 |
arg2Of |
mutagenesis,performed |
| R39760 |
T72703 |
T44486 |
arg2Of |
levels,in |
| R398 |
T403 |
T402 |
arg1Of |
receptor,cellular |
| R3981 |
T3483 |
T60967 |
arg1Of |
performed,"," |
| R39812 |
T54925 |
T25318 |
arg1Of |
analyses,of |
| R39821 |
T23904 |
T10927 |
arg1Of |
PNGs,existing |
| R39844 |
T92110 |
T12304 |
arg1Of |
glycans,and |
| R39856 |
T10053 |
T71408 |
arg1Of |
speculate,"," |
| R39868 |
T28685 |
T16798 |
arg2Of |
proteins,of |
| R39879 |
T74217 |
T58888 |
arg2Of |
and,including |
| R399 |
T406 |
T404 |
arg1Of |
proteins,CoV |
| R3992 |
T75213 |
T12698 |
arg1Of |
peptide,the |
| R400 |
T406 |
T405 |
arg1Of |
proteins,S |
| R40020 |
T97014 |
T22448 |
arg1Of |
response,immune |
| R401 |
T406 |
T407 |
arg1Of |
proteins,are |
| R40112 |
T3174 |
T8430 |
arg1Of |
Env,HIV-1 |
| R40128 |
T20023 |
T85837 |
arg2Of |
reservoirs,in |
| R40133 |
T66804 |
T71072 |
arg1Of |
surface,"," |
| R40189 |
T20594 |
T55010 |
arg1Of |
residues,on |
| R402 |
T415 |
T407 |
arg2Of |
known9,are |
| R40238 |
T66745 |
T21467 |
arg1Of |
trimer,the |
| R40241 |
T58945 |
T28579 |
arg1Of |
number,total |
| R40261 |
T26450 |
T82660 |
arg3Of |
),( |
| R40287 |
T29223 |
T85418 |
arg1Of |
glycans,( |
| R403 |
T415 |
T408 |
arg1Of |
known9,the |
| R40328 |
T82693 |
T92120 |
arg2Of |
and,analysed |
| R40335 |
T46887 |
T75407 |
arg1Of |
sites,receptor-binding |
| R40358 |
T92910 |
T14256 |
arg1Of |
Residues,with |
| R40383 |
T17551 |
T64406 |
arg1Of |
shields,the |
| R40393 |
T10541 |
T36690 |
arg1Of |
viruses,two |
| R404 |
T415 |
T409 |
arg1Of |
known9,largest |
| R4041 |
T64807 |
T17288 |
arg1Of |
hemagglutinin,H3N2 |
| R40464 |
T30217 |
T58506 |
arg1Of |
modelling,The |
| R40472 |
T79677 |
T51290 |
arg1Of |
maps,are |
| R40497 |
T63261 |
T55283 |
arg2Of |
leads,showed51 |
| R405 |
T415 |
T410 |
arg1Of |
known9,class |
| R40578 |
T35349 |
T43036 |
arg1Of |
subunits,The |
| R406 |
T415 |
T411 |
arg1Of |
known9,I |
| R40679 |
T13068 |
T59646 |
arg1Of |
functionality,the |
| R407 |
T415 |
T412 |
arg1Of |
known9,viral |
| R40704 |
T89744 |
T23520 |
arg2Of |
antibodies,of |
| R40757 |
T57983 |
T18742 |
arg1Of |
"shield54,55",effective |
| R40791 |
T37461 |
T30415 |
arg2Of |
it,compare |
| R408 |
T415 |
T413 |
arg1Of |
known9,fusion |
| R40876 |
T74143 |
T67520 |
arg1Of |
density,overall |
| R409 |
T415 |
T414 |
arg1Of |
known9,proteins |
| R40920 |
T3180 |
T1782 |
arg1Of |
analysis,HILIC-UPLC |
| R40924 |
T55408 |
T2961 |
arg2Of |
ratio,had |
| R40953 |
T81925 |
T61603 |
arg1Of |
proteins,SARS |
| R40971 |
T28413 |
T30887 |
arg1Of |
targets,are |
| R40982 |
T90081 |
T40209 |
arg1Of |
exhibit,not |
| R410 |
T417 |
T416 |
arg1Of |
and,"," |
| R41063 |
T90139 |
T52708 |
arg1Of |
generated,from |
| R411 |
T407 |
T417 |
arg1Of |
are,and |
| R41117 |
T59031 |
T90575 |
arg1Of |
glycans,the |
| R41132 |
T26477 |
T12300 |
arg1Of |
Left,; |
| R41133 |
T61708 |
T19879 |
arg2Of |
5VK2,"," |
| R412 |
T420 |
T417 |
arg2Of |
glycosylated,and |
| R41263 |
T33037 |
T82290 |
arg1Of |
MERS,and |
| R41271 |
T83973 |
T14068 |
arg1Of |
residues,exposed |
| R413 |
T406 |
T418 |
arg1Of |
proteins,are |
| R41315 |
T30415 |
T70541 |
arg2Of |
compare,and |
| R41325 |
T6621 |
T61778 |
arg1Of |
contribute,For |
| R41359 |
T26380 |
T35353 |
arg2Of |
value,with |
| R414 |
T420 |
T418 |
arg2Of |
glycosylated,are |
| R41447 |
T55295 |
T82828 |
arg1Of |
proteins,including |
| R415 |
T420 |
T419 |
arg1Of |
glycosylated,extensively |
| R41505 |
T58945 |
T41351 |
arg2Of |
number,by |
| R41577 |
T47272 |
T87179 |
arg1Of |
fusion,receptor-binding |
| R41585 |
T76651 |
T24947 |
modOf |
assortment,to |
| R416 |
T406 |
T420 |
arg2Of |
proteins,glycosylated |
| R41625 |
T31427 |
T20303 |
arg1Of |
proteins,S |
| R41690 |
T12133 |
T46991 |
arg1Of |
5X58,ID |
| R417 |
T420 |
T421 |
arg1Of |
glycosylated,"," |
| R41744 |
T45067 |
T82041 |
arg1Of |
glycans,would |
| R418 |
T420 |
T422 |
arg1Of |
glycosylated,with |
| R41802 |
T9118 |
T91856 |
arg1Of |
oligomannose-type,fully |
| R4181 |
T58744 |
T47642 |
arg1Of |
quality,( |
| R41821 |
T35349 |
T63087 |
arg1Of |
subunits,S2 |
| R41822 |
T25121 |
T91373 |
arg2Of |
deletions,and |
| R41837 |
T87267 |
T68020 |
arg1Of |
glycans,the |
| R41847 |
T75223 |
T69929 |
arg1Of |
observe,whereas |
| R419 |
T427 |
T422 |
arg2Of |
glycoproteins,with |
| R4190 |
T58510 |
T60171 |
arg1Of |
level,a |
| R41908 |
T93138 |
T45227 |
arg2Of |
digested,were |
| R41935 |
T30499 |
T56293 |
arg1Of |
accessibility,of |
| R420 |
T427 |
T423 |
arg1Of |
glycoproteins,SARS |
| R42008 |
T73464 |
T91677 |
arg1Of |
library,glycan |
| R42024 |
T5164 |
T85081 |
arg1Of |
modelling,of |
| R421 |
T423 |
T424 |
arg1Of |
SARS,and |
| R42106 |
T61083 |
T70472 |
arg1Of |
and,which |
| R42132 |
T61777 |
T53697 |
arg2Of |
maps,in |
| R422 |
T425 |
T424 |
arg2Of |
MERS,and |
| R42213 |
T81627 |
T18761 |
arg2Of |
grouped,and |
| R42276 |
T45843 |
T96415 |
arg2Of |
complex,in |
| R423 |
T427 |
T425 |
arg1Of |
glycoproteins,MERS |
| R4234 |
T17645 |
T91429 |
arg1Of |
sites,that |
| R42340 |
T45067 |
T32694 |
arg1Of |
glycans,these |
| R424 |
T427 |
T426 |
arg1Of |
glycoproteins,S |
| R42415 |
T24662 |
T41800 |
arg1Of |
GPC,which |
| R42488 |
T7370 |
T27090 |
arg1Of |
isolated,more |
| R425 |
T429 |
T428 |
arg1Of |
encoding,both |
| R42509 |
T84080 |
T27673 |
arg1Of |
changes,no |
| R42599 |
T68442 |
T5395 |
arg1Of |
domains,S1 |
| R426 |
T427 |
T429 |
arg1Of |
glycoproteins,encoding |
| R42646 |
T1963 |
T22023 |
arg2Of |
implicated,been |
| R42650 |
T89591 |
T85913 |
arg2Of |
shown,are |
| R427 |
T433 |
T429 |
arg2Of |
sequons,encoding |
| R42703 |
T25304 |
T27779 |
arg1Of |
sequences,available |
| R42722 |
T68543 |
T48920 |
arg1Of |
glycoproteins,viral |
| R42761 |
T30887 |
T56103 |
arg1Of |
are,"," |
| R428 |
T433 |
T430 |
arg1Of |
sequons,69 |
| R42808 |
T74594 |
T33006 |
arg1Of |
structure,the |
| R42830 |
T96477 |
T31963 |
arg1Of |
amino-acids,interact |
| R42837 |
T66804 |
T23712 |
arg1Of |
surface,surface |
| R429 |
T433 |
T431 |
arg1Of |
sequons,N-linked |
| R42900 |
T11057 |
T72208 |
arg1Of |
analysis,of |
| R42903 |
T33263 |
T91161 |
arg1Of |
and,for |
| R42911 |
T27706 |
T3633 |
arg1Of |
and,( |
| R42935 |
T49864 |
T33083 |
arg1Of |
glycans,( |
| R42948 |
T37933 |
T95071 |
arg3Of |
and,observed |
| R430 |
T433 |
T432 |
arg1Of |
sequons,glycan |
| R43019 |
T13068 |
T56626 |
arg1Of |
functionality,intrinsic |
| R431 |
T433 |
T434 |
arg1Of |
sequons,per |
| R43123 |
T13983 |
T15475 |
arg1Of |
arise,"," |
| R43138 |
T2686 |
T61552 |
arg1Of |
shield,the |
| R432 |
T436 |
T434 |
arg2Of |
spike,per |
| R43217 |
T19161 |
T96776 |
arg1Of |
reminiscent,of |
| R43254 |
T21412 |
T34895 |
arg2Of |
plotted,and |
| R43272 |
T25862 |
T59533 |
arg1Of |
glycosylated,fully |
| R433 |
T436 |
T435 |
arg1Of |
spike,trimeric |
| R43325 |
T23904 |
T45261 |
arg1Of |
PNGs,rather |
| R43360 |
T43250 |
T52169 |
arg1Of |
results,in |
| R434 |
T436 |
T437 |
arg1Of |
spike,with |
| R43446 |
T72666 |
T29830 |
arg1Of |
approach,which |
| R43475 |
T44348 |
T26533 |
arg1Of |
MERS,a |
| R435 |
T438 |
T437 |
arg2Of |
SARS-CoV-2,with |
| R43507 |
T65533 |
T63649 |
arg2Of |
coronavirus,of |
| R43509 |
T30217 |
T75169 |
arg1Of |
modelling,is |
| R43519 |
T79396 |
T13436 |
arg2Of |
fail,but |
| R43549 |
T71311 |
T55810 |
arg1Of |
number,the |
| R43590 |
T83020 |
T39523 |
arg1Of |
presence,of |
| R43596 |
T47078 |
T70372 |
arg1Of |
possesses,"," |
| R436 |
T438 |
T439 |
arg1Of |
SARS-CoV-2,containing |
| R43624 |
T69399 |
T37758 |
arg2Of |
glycans,from |
| R43629 |
T32530 |
T12832 |
arg2Of |
are,Although |
| R43660 |
T90304 |
T48372 |
arg1Of |
Fig. 8,SI |
| R437 |
T441 |
T439 |
arg2Of |
sites,containing |
| R43706 |
T86749 |
T48770 |
arg1Of |
to,due |
| R43741 |
T11314 |
T81842 |
arg1Of |
Env,surface |
| R43772 |
T12246 |
T83739 |
arg2Of |
sites,in |
| R43779 |
T83984 |
T27307 |
arg1Of |
it,may |
| R438 |
T441 |
T440 |
arg1Of |
sites,66 |
| R43806 |
T78856 |
T43948 |
arg1Of |
research,coronavirus |
| R43856 |
T28413 |
T16688 |
arg1Of |
targets,for |
| R439 |
T443 |
T442 |
arg1Of |
modifications,These |
| R43979 |
T2696 |
T40337 |
arg2Of |
occluded,surprising |
| R43983 |
T82375 |
T45711 |
arg3Of |
),( |
| R440 |
T445 |
T444 |
arg1Of |
mask,often |
| R44043 |
T85744 |
T95434 |
arg1Of |
immunity65,mucosal |
| R44071 |
T65533 |
T59243 |
arg1Of |
coronavirus,SARS |
| R4409 |
T49864 |
T40035 |
arg2Of |
glycans,fucosylated |
| R441 |
T443 |
T445 |
arg1Of |
modifications,mask |
| R44107 |
T6955 |
T40144 |
arg1Of |
apart,from |
| R44135 |
T31301 |
T96403 |
arg1Of |
and,PDB |
| R44147 |
T85741 |
T18381 |
arg1Of |
map,the |
| R44156 |
T20304 |
T57102 |
arg1Of |
differences,in |
| R442 |
T448 |
T445 |
arg2Of |
epitopes,mask |
| R44274 |
T58945 |
T84292 |
arg1Of |
number,of |
| R44281 |
T10053 |
T45372 |
arg2Of |
speculate,tempting |
| R4429 |
T71311 |
T36859 |
arg1Of |
number,of |
| R443 |
T448 |
T446 |
arg1Of |
epitopes,immunogenic |
| R44314 |
T38232 |
T35432 |
arg1Of |
traces,with |
| R44339 |
T94857 |
T50642 |
arg1Of |
Mapping,dN/dS |
| R44359 |
T68640 |
T12304 |
arg2Of |
proteins,and |
| R44377 |
T86129 |
T85948 |
arg1Of |
viruses,perturbing |
| R44378 |
T3262 |
T46103 |
arg1Of |
glycoproteins,MERS |
| R444 |
T448 |
T447 |
arg1Of |
epitopes,protein |
| R44430 |
T33229 |
T36523 |
arg3Of |
being,with |
| R44451 |
T46741 |
T29063 |
arg3Of |
),( |
| R44466 |
T74546 |
T66965 |
arg1Of |
investigated,during |
| R44474 |
T31010 |
T21278 |
arg1Of |
correlation,was |
| R44490 |
T94035 |
T84875 |
arg2Of |
and,generated |
| R445 |
T448 |
T449 |
arg1Of |
epitopes,from |
| R44507 |
T10541 |
T54679 |
arg1Of |
viruses,the |
| R44564 |
T23338 |
T81584 |
arg1Of |
HA50,influenza |
| R44596 |
T61083 |
T83245 |
arg2Of |
and,of |
| R446 |
T454 |
T449 |
arg2Of |
system,from |
| R44667 |
T68543 |
T26853 |
arg1Of |
glycoproteins,were |
| R447 |
T454 |
T450 |
arg1Of |
system,the |
| R44708 |
T61369 |
T23395 |
arg1Of |
ratio,the |
| R44731 |
T66273 |
T73691 |
arg1Of |
biomolecules,and |
| R44751 |
T90188 |
T5712 |
arg1Of |
map,( |
| R4478 |
T44180 |
T85300 |
arg3Of |
),( |
| R448 |
T454 |
T451 |
arg1Of |
system,host |
| R44817 |
T20048 |
T5602 |
arg1Of |
response,immune |
| R4483 |
T33538 |
T88529 |
arg1Of |
glycosylation,does |
| R44853 |
T90485 |
T16896 |
arg1Of |
exemplifies,as |
| R44856 |
T95927 |
T12646 |
arg2Of |
fucosylation,of |
| R44894 |
T21025 |
T57630 |
arg1Of |
abundances,Oligomannose |
| R449 |
T454 |
T452 |
arg1Of |
system,humoral |
| R44924 |
T55408 |
T37460 |
arg1Of |
ratio,dN/dS |
| R44930 |
T85744 |
T40686 |
arg2Of |
immunity65,produce |
| R4494 |
T97014 |
T84588 |
arg1Of |
response,to |
| R44950 |
T8574 |
T84302 |
arg1Of |
highlighted,when |
| R44953 |
T58389 |
T28787 |
arg1Of |
Investigation,of |
| R450 |
T454 |
T453 |
arg1Of |
system,immune |
| R45016 |
T82084 |
T6952 |
arg1Of |
S,MERS |
| R451 |
T445 |
T455 |
arg1Of |
mask,by |
| R45114 |
T6523 |
T15902 |
arg2Of |
interesting,is |
| R45134 |
T86925 |
T92642 |
arg1Of |
series,( |
| R45175 |
T24662 |
T50837 |
arg1Of |
GPC,smaller |
| R4519 |
T38232 |
T94309 |
arg1Of |
traces,backbone |
| R452 |
T456 |
T455 |
arg2Of |
occluding,by |
| R45240 |
T99824 |
T42535 |
arg1Of |
density,"," |
| R45247 |
T46678 |
T91843 |
arg1Of |
we,performed |
| R45262 |
T68442 |
T9018 |
arg1Of |
domains,N-terminal |
| R45273 |
T1670 |
T25939 |
arg2Of |
trimming,revealed |
| R45278 |
T83381 |
T40184 |
arg1Of |
glycosylation,surface |
| R453 |
T443 |
T456 |
arg1Of |
modifications,occluding |
| R45316 |
T93322 |
T15821 |
arg2Of |
context,in |
| R45373 |
T55295 |
T57622 |
arg2Of |
proteins,of |
| R45386 |
T79677 |
T28675 |
arg1Of |
maps,sensitive |
| R454 |
T457 |
T456 |
arg2Of |
them,occluding |
| R45480 |
T28935 |
T30994 |
arg1Of |
behaviour,epidemic |
| R45481 |
T1963 |
T69555 |
arg1Of |
implicated,"," |
| R45489 |
T80173 |
T31925 |
arg1Of |
",","," |
| R455 |
T456 |
T458 |
arg1Of |
occluding,with |
| R45510 |
T56273 |
T63629 |
arg2Of |
map,Sharpened |
| R45513 |
T70541 |
T81037 |
arg1Of |
and,"," |
| R4552 |
T34506 |
T30497 |
arg1Of |
with,in |
| R45550 |
T54331 |
T78244 |
arg2Of |
SARS,on |
| R45557 |
T43194 |
T27706 |
arg1Of |
antennae,and |
| R45570 |
T74010 |
T62658 |
arg1Of |
easily,more |
| R456 |
T460 |
T458 |
arg2Of |
glycans16–18,with |
| R4568 |
T99830 |
T19398 |
arg2Of |
hindered,would |
| R45689 |
T47239 |
T7211 |
arg3Of |
),( |
| R45699 |
T23058 |
T71875 |
arg1Of |
Fig. 7,SI |
| R457 |
T460 |
T459 |
arg1Of |
glycans16–18,host-derived |
| R45720 |
T19203 |
T98351 |
arg2Of |
dataset,in |
| R45768 |
T67481 |
T99058 |
arg2Of |
such,As |
| R45792 |
T15804 |
T53332 |
arg2Of |
elicit,able |
| R45798 |
T64807 |
T69427 |
arg1Of |
hemagglutinin,( |
| R458 |
T462 |
T461 |
arg1Of |
phenomenon,This |
| R45822 |
T24662 |
T66930 |
arg1Of |
GPC,"," |
| R45835 |
T59734 |
T62851 |
arg1Of |
constraints,functional |
| R45850 |
T72037 |
T23602 |
arg1Of |
most,of |
| R45865 |
T40726 |
T54827 |
arg1Of |
spikes,MERS |
| R459 |
T462 |
T463 |
arg1Of |
phenomenon,of |
| R45968 |
T72299 |
T18939 |
arg2Of |
and,between |
| R45989 |
T49217 |
T66723 |
arg1Of |
3,Fig. |
| R460 |
T465 |
T463 |
arg2Of |
evasion,of |
| R46003 |
T53332 |
T49759 |
arg2Of |
able,are |
| R46016 |
T57528 |
T46492 |
arg2Of |
regions,and |
| R46093 |
T78881 |
T31925 |
arg2Of |
4O5N,"," |
| R461 |
T465 |
T464 |
arg1Of |
evasion,immune |
| R46106 |
T84163 |
T11703 |
arg2Of |
FA4,to |
| R46136 |
T68442 |
T72184 |
arg1Of |
domains,extending |
| R462 |
T462 |
T466 |
arg1Of |
phenomenon,by |
| R46219 |
T76130 |
T75367 |
arg1Of |
site,receptor-binding |
| R46249 |
T27706 |
T75194 |
arg1Of |
and,( |
| R46291 |
T49179 |
T34506 |
arg2Of |
vitro59,with |
| R463 |
T469 |
T466 |
arg2Of |
and,by |
| R46306 |
T11621 |
T84900 |
arg1Of |
offer,not |
| R4632 |
T2559 |
T24147 |
arg1Of |
grey,and |
| R46333 |
T85744 |
T65430 |
arg1Of |
immunity65,sufficient |
| R464 |
T468 |
T467 |
arg1Of |
mimicry,molecular |
| R46405 |
T10989 |
T31245 |
arg2Of |
"response21,31",from |
| R46471 |
T85689 |
T43310 |
arg2Of |
proportion,occludes |
| R46477 |
T55295 |
T77114 |
arg1Of |
proteins,viral |
| R465 |
T468 |
T469 |
arg1Of |
mimicry,and |
| R46535 |
T28413 |
T23034 |
arg1Of |
targets,likely |
| R46556 |
T21879 |
T97449 |
arg1Of |
S,( |
| R46559 |
T18714 |
T16269 |
arg1Of |
shield,which |
| R4656 |
T51052 |
T89745 |
arg1Of |
observed,on |
| R46593 |
T30265 |
T8292 |
arg1Of |
reproduced,from |
| R466 |
T471 |
T469 |
arg2Of |
shielding,and |
| R46603 |
T26533 |
T48343 |
arg1Of |
a,( |
| R46655 |
T49864 |
T85300 |
arg1Of |
glycans,( |
| R46661 |
T63465 |
T16896 |
arg2Of |
virus,as |
| R46674 |
T7550 |
T2009 |
arg2Of |
accumulation,to |
| R46682 |
T62928 |
T41459 |
arg1Of |
glycans,here |
| R467 |
T471 |
T470 |
arg1Of |
shielding,glycan |
| R4670 |
T67337 |
T2332 |
arg1Of |
cluster,this |
| R46738 |
T28555 |
T69590 |
arg2Of |
such,As |
| R46751 |
T4558 |
T25400 |
arg2Of |
domains,of |
| R46764 |
T88367 |
T70083 |
arg1Of |
levels,of |
| R46771 |
T95274 |
T70578 |
arg2Of |
vulnerability,of |
| R468 |
T462 |
T472 |
arg1Of |
phenomenon,has |
| R46838 |
T90138 |
T82634 |
arg2Of |
SARS,and |
| R469 |
T475 |
T472 |
arg2Of |
characterised,has |
| R470 |
T462 |
T473 |
arg1Of |
phenomenon,been |
| R47042 |
T53941 |
T90782 |
arg1Of |
SOSIP.664,HIV-1 |
| R47087 |
T89747 |
T50969 |
arg2Of |
accretion,limit |
| R471 |
T475 |
T473 |
arg2Of |
characterised,been |
| R47110 |
T8069 |
T79028 |
arg2Of |
glycan28,access |
| R47138 |
T64538 |
T97000 |
arg1Of |
notion,This |
| R47143 |
T12192 |
T69312 |
arg2Of |
presented,and |
| R47162 |
T86129 |
T8489 |
arg1Of |
viruses,other |
| R47190 |
T42487 |
T44308 |
arg1Of |
evaluation,an |
| R472 |
T475 |
T474 |
arg1Of |
characterised,well |
| R47204 |
T53169 |
T28124 |
arg2Of |
GPC,"," |
| R47214 |
T97427 |
T80942 |
arg1Of |
and,both |
| R47263 |
T40726 |
T64040 |
arg2Of |
spikes,and |
| R473 |
T462 |
T475 |
arg2Of |
phenomenon,characterised |
| R47307 |
T91973 |
T67415 |
arg1Of |
but,"," |
| R47308 |
T92070 |
T38048 |
arg2Of |
proteins,of |
| R47345 |
T96851 |
T93743 |
arg2Of |
substitutions,to |
| R474 |
T475 |
T476 |
arg1Of |
characterised,across |
| R47461 |
T2132 |
T30799 |
arg1Of |
fucosylation,and |
| R47491 |
T22031 |
T76564 |
arg2Of |
analysis,performed |
| R475 |
T479 |
T476 |
arg2Of |
glycoproteins,across |
| R47551 |
T52910 |
T73267 |
arg1Of |
and,for |
| R47563 |
T7777 |
T27277 |
arg2Of |
regions,in |
| R47592 |
T52475 |
T58850 |
arg1Of |
conservation,of |
| R476 |
T479 |
T477 |
arg1Of |
glycoproteins,other |
| R47619 |
T18965 |
T72137 |
arg1Of |
proteins,from |
| R47642 |
T71776 |
T35226 |
arg1Of |
interactions,drive |
| R4765 |
T6629 |
T64812 |
arg1Of |
compositions,their |
| R47678 |
T72393 |
T19972 |
arg2Of |
reprocessed,was |
| R47689 |
T13068 |
T18164 |
arg2Of |
functionality,from |
| R47693 |
T67976 |
T10009 |
arg2Of |
glycome,studied |
| R477 |
T479 |
T478 |
arg1Of |
glycoproteins,viral |
| R47712 |
T19500 |
T8001 |
arg2Of |
with,"," |
| R478 |
T479 |
T480 |
arg1Of |
glycoproteins,"," |
| R47828 |
T79246 |
T85438 |
arg1Of |
oligomannose,"," |
| R47832 |
T61005 |
T36851 |
arg1Of |
Env,HIV-1 |
| R47847 |
T72195 |
T32938 |
arg1Of |
recognition,innate |
| R479 |
T482 |
T481 |
arg1Of |
as,such |
| R4790 |
T59734 |
T18450 |
arg1Of |
constraints,"," |
| R47903 |
T19690 |
T64282 |
arg1Of |
weight,molecular |
| R47914 |
T25884 |
T91293 |
arg1Of |
values,Averaged |
| R47946 |
T71298 |
T42034 |
arg1Of |
glycoproteins,"," |
| R47997 |
T33036 |
T26191 |
arg1Of |
subunit,this |
| R480 |
T479 |
T482 |
arg1Of |
glycoproteins,as |
| R48001 |
T72197 |
T51090 |
arg2Of |
glycoproteins,to |
| R48079 |
T43250 |
T2441 |
arg1Of |
results,at |
| R481 |
T497 |
T482 |
arg2Of |
and,as |
| R482 |
T485 |
T483 |
arg1Of |
protein,HIV-1 |
| R48201 |
T72369 |
T85886 |
arg2Of |
substitutions,of |
| R48243 |
T68681 |
T47375 |
arg1Of |
knock,to |
| R48247 |
T91715 |
T67031 |
arg1Of |
glycoproteins,"," |
| R4827 |
T31427 |
T86504 |
arg2Of |
proteins,alkylated |
| R483 |
T485 |
T484 |
arg1Of |
protein,envelope |
| R48312 |
T15412 |
T5507 |
arg1Of |
domains,that |
| R48342 |
T64331 |
T68155 |
arg1Of |
ratios,compared |
| R4839 |
T52754 |
T74888 |
arg1Of |
MERS,the |
| R48396 |
T2410 |
T71292 |
arg2Of |
sites,of |
| R484 |
T492 |
T485 |
arg1Of |
hemagglutinin,protein |
| R485 |
T485 |
T486 |
arg1Of |
protein,( |
| R48506 |
T36827 |
T39186 |
arg1Of |
we,found |
| R48535 |
T5294 |
T43304 |
arg1Of |
:,Same |
| R48587 |
T83973 |
T81366 |
arg1Of |
residues,across |
| R486 |
T487 |
T486 |
arg2Of |
Env,( |
| R48661 |
T34602 |
T35226 |
arg2Of |
structuring,drive |
| R48676 |
T79360 |
T22927 |
arg3Of |
),( |
| R48682 |
T31427 |
T8652 |
arg2Of |
proteins,digested |
| R487 |
T488 |
T486 |
arg3Of |
),( |
| R4871 |
T44348 |
T9629 |
arg1Of |
MERS,and |
| R488 |
T485 |
T489 |
arg1Of |
protein,19–21 |
| R48801 |
T48779 |
T50978 |
arg1Of |
indicated,in |
| R48827 |
T32624 |
T48510 |
arg1Of |
diversity,low |
| R4883 |
T15871 |
T73572 |
arg1Of |
March,2020 |
| R48890 |
T38716 |
T23248 |
arg1Of |
note,it |
| R489 |
T485 |
T490 |
arg1Of |
protein,"," |
| R48951 |
T13436 |
T32116 |
arg1Of |
but,"," |
| R48982 |
T81512 |
T36523 |
arg2Of |
18,with |
| R48987 |
T20023 |
T29947 |
arg1Of |
reservoirs,their |
| R490 |
T491 |
T490 |
arg2Of |
influenza,"," |
| R49041 |
T30887 |
T81494 |
modOf |
are,resulting |
| R49061 |
T59632 |
T61432 |
arg2Of |
unable,are |
| R49064 |
T28690 |
T40406 |
arg2Of |
disallow,and |
| R49097 |
T54724 |
T84302 |
arg2Of |
mapped,when |
| R491 |
T492 |
T491 |
arg1Of |
hemagglutinin,influenza |
| R49150 |
T29760 |
T53742 |
arg1Of |
repeat,one |
| R49164 |
T86129 |
T10448 |
arg1Of |
viruses,are |
| R492 |
T492 |
T493 |
arg1Of |
hemagglutinin,( |
| R49206 |
T19161 |
T38719 |
arg2Of |
reminiscent,is |
| R49214 |
T59031 |
T7370 |
arg1Of |
glycans,isolated |
| R49275 |
T82693 |
T86575 |
arg2Of |
and,with |
| R4929 |
T73605 |
T82163 |
arg1Of |
flexibility,of |
| R493 |
T494 |
T493 |
arg2Of |
HA,( |
| R4932 |
T95444 |
T32530 |
arg2Of |
available,are |
| R49381 |
T12652 |
T92287 |
arg1Of |
residues,exhibited |
| R49383 |
T76860 |
T24256 |
arg1Of |
glycans,are |
| R494 |
T495 |
T493 |
arg3Of |
),( |
| R49403 |
T68609 |
T79273 |
arg1Of |
structures,the |
| R49442 |
T91463 |
T52453 |
arg3Of |
coming,with |
| R49465 |
T10989 |
T10149 |
arg1Of |
"response21,31",the |
| R49480 |
T74143 |
T65417 |
arg1Of |
density,differ |
| R495 |
T492 |
T496 |
arg1Of |
hemagglutinin,"22,23" |
| R49514 |
T21366 |
T42060 |
arg1Of |
sites,potential |
| R4952 |
T90192 |
T33187 |
arg1Of |
number,the |
| R49529 |
T44450 |
T32211 |
arg1Of |
coronaviruses,elicit |
| R49539 |
T70602 |
T31999 |
arg2Of |
Assemblies,and |
| R496 |
T492 |
T497 |
arg1Of |
hemagglutinin,and |
| R49617 |
T16112 |
T11619 |
arg1Of |
diversification,Amino-acid |
| R49633 |
T80856 |
T94093 |
arg1Of |
SARS,and |
| R49659 |
T83984 |
T34676 |
arg1Of |
it,be |
| R497 |
T501 |
T497 |
arg2Of |
complex,and |
| R49729 |
T81137 |
T95497 |
arg2Of |
common,in |
| R49756 |
T1963 |
T79414 |
arg2Of |
implicated,has |
| R49770 |
T49099 |
T58919 |
arg1Of |
domain,and |
| R498 |
T501 |
T498 |
arg1Of |
complex,Lassa |
| R49825 |
T72291 |
T42416 |
arg1Of |
colored,respectively |
| R4989 |
T67339 |
T83021 |
arg1Of |
classified,historically |
| R499 |
T501 |
T499 |
arg1Of |
complex,virus |
| R4990 |
T61083 |
T16556 |
arg1Of |
and,was |
| R49906 |
T61867 |
T39961 |
arg1Of |
GPC,LASV |
| R49912 |
T74594 |
T14723 |
arg2Of |
structure,on |
| R49923 |
T16458 |
T19972 |
arg1Of |
dataset52,was |
| R4994 |
T94871 |
T29556 |
arg1Of |
shield,glycan |
| R49965 |
T7777 |
T89562 |
arg1Of |
regions,the |
| R500 |
T501 |
T500 |
arg1Of |
complex,glycoprotein |
| R50005 |
T42122 |
T96563 |
arg1Of |
signal,low |
| R501 |
T501 |
T502 |
arg1Of |
complex,( |
| R50107 |
T24662 |
T43310 |
arg1Of |
GPC,occludes |
| R50123 |
T68738 |
T17336 |
arg2Of |
comparable,are |
| R50127 |
T18666 |
T75900 |
arg1Of |
spectrometry,liquid |
| R50130 |
T43310 |
T57424 |
arg1Of |
occludes,with |
| R50155 |
T34772 |
T66915 |
arg2Of |
Asn236,and |
| R50174 |
T78948 |
T68155 |
arg2Of |
with,compared |
| R502 |
T504 |
T502 |
arg2Of |
GPC,( |
| R50205 |
T53506 |
T70792 |
arg1Of |
is,"," |
| R50247 |
T94405 |
T25862 |
arg1Of |
model,glycosylated |
| R50264 |
T68729 |
T34685 |
arg2Of |
volume,and |
| R503 |
T505 |
T502 |
arg3Of |
),( |
| R50307 |
T90188 |
T98545 |
arg1Of |
map,filtered |
| R50333 |
T12304 |
T83177 |
arg2Of |
and,of |
| R50360 |
T68396 |
T16273 |
arg1Of |
MS,LC-ESI |
| R50373 |
T8574 |
T87038 |
arg1Of |
highlighted,"," |
| R50397 |
T15627 |
T43286 |
arg1Of |
nanobodies,penetrate |
| R504 |
T504 |
T503 |
arg1Of |
GPC,LASV |
| R50475 |
T19099 |
T77842 |
arg1Of |
protrude,away |
| R505 |
T501 |
T506 |
arg1Of |
complex,24–26 |
| R50544 |
T8512 |
T12260 |
arg2Of |
coronaviruses,of |
| R50550 |
T86335 |
T63374 |
arg2Of |
glycan,of |
| R50563 |
T18965 |
T40757 |
arg1Of |
proteins,S |
| R50586 |
T33045 |
T90570 |
arg1Of |
quantification,of |
| R506 |
T508 |
T507 |
arg1Of |
analyses,Previous |
| R50639 |
T3337 |
T80636 |
arg1Of |
shield51,Env |
| R50646 |
T30217 |
T85671 |
arg2Of |
modelling,illustrated |
| R50668 |
T99242 |
T28913 |
arg1Of |
head,the |
| R507 |
T508 |
T509 |
arg1Of |
analyses,of |
| R50718 |
T2410 |
T61275 |
arg1Of |
sites,glycan |
| R508 |
T512 |
T509 |
arg2Of |
shields,of |
| R50879 |
T96423 |
T51670 |
arg1Of |
spikes,glycosylated |
| R509 |
T512 |
T510 |
arg1Of |
shields,viral |
| R50925 |
T74519 |
T69698 |
arg2Of |
glycans,clustered |
| R510 |
T512 |
T511 |
arg1Of |
shields,glycan |
| R511 |
T508 |
T513 |
arg1Of |
analyses,have |
| R51120 |
T50573 |
T29922 |
arg1Of |
and,for |
| R51133 |
T55061 |
T81144 |
arg1Of |
cells,canine |
| R51134 |
T96477 |
T57287 |
arg1Of |
amino-acids,that |
| R51193 |
T46357 |
T17558 |
arg2Of |
differences,divided |
| R512 |
T514 |
T513 |
arg2Of |
revealed,have |
| R51225 |
T6892 |
T83032 |
arg2Of |
likely,is |
| R513 |
T508 |
T514 |
arg1Of |
analyses,revealed |
| R51304 |
T4129 |
T94035 |
arg2Of |
5X58,and |
| R51307 |
T82481 |
T19623 |
arg1Of |
subunit,to |
| R51342 |
T85070 |
T7334 |
arg2Of |
it,"," |
| R51375 |
T80657 |
T69498 |
arg1Of |
protein,class |
| R514 |
T516 |
T514 |
arg2Of |
presence,revealed |
| R5141 |
T83825 |
T42572 |
arg1Of |
indicate,onto |
| R51441 |
T11621 |
T46258 |
arg2Of |
offer,would |
| R51450 |
T78348 |
T5501 |
arg1Of |
Fig. 5,SI |
| R515 |
T516 |
T515 |
arg1Of |
presence,the |
| R51542 |
T70323 |
T76643 |
arg2Of |
proteins,of |
| R516 |
T516 |
T517 |
arg1Of |
presence,of |
| R51633 |
T38606 |
T86025 |
arg1Of |
GPC,LASV |
| R517 |
T520 |
T517 |
arg2Of |
glycans,of |
| R518 |
T520 |
T518 |
arg1Of |
glycans,underprocessed |
| R519 |
T520 |
T519 |
arg1Of |
glycans,oligomannose-type |
| R51926 |
T50082 |
T32901 |
arg1Of |
S,MERS |
| R51930 |
T18761 |
T31666 |
arg1Of |
and,"," |
| R51942 |
T70323 |
T65032 |
arg1Of |
proteins,CoV |
| R520 |
T520 |
T521 |
arg1Of |
glycans,that |
| R52004 |
T90347 |
T30100 |
arg2Of |
proteins,of |
| R52010 |
T76573 |
T10460 |
arg1Of |
",",and |
| R52020 |
T68543 |
T82274 |
arg2Of |
glycoproteins,analysed |
| R52028 |
T76361 |
T97427 |
arg2Of |
proteins,and |
| R521 |
T523 |
T522 |
arg1Of |
arise,seemingly |
| R52171 |
T54061 |
T95868 |
arg1Of |
proteins,S |
| R52176 |
T1949 |
T13865 |
arg2Of |
diversity,of |
| R52190 |
T53788 |
T31069 |
arg1Of |
functionality,the |
| R522 |
T520 |
T523 |
arg1Of |
glycans,arise |
| R52218 |
T17864 |
T39535 |
arg1Of |
processing,glycan |
| R52224 |
T8512 |
T89645 |
arg1Of |
coronaviruses,important |
| R52288 |
T89162 |
T87732 |
arg1Of |
as,can |
| R52293 |
T40498 |
T99309 |
arg1Of |
lack,the |
| R52294 |
T86019 |
T3693 |
arg1Of |
Fig.,4 |
| R523 |
T525 |
T524 |
arg1Of |
to,due |
| R52342 |
T39941 |
T86297 |
arg1Of |
genes,current |
| R524 |
T523 |
T525 |
arg1Of |
arise,to |
| R52410 |
T7069 |
T41089 |
arg1Of |
correspond,to |
| R52418 |
T3483 |
T74853 |
arg1Of |
performed,on |
| R52454 |
T65049 |
T82162 |
arg2Of |
maintaining,as |
| R525 |
T527 |
T525 |
arg2Of |
constraints,to |
| R52503 |
T16458 |
T72393 |
arg2Of |
dataset52,reprocessed |
| R52525 |
T65533 |
T97323 |
arg1Of |
coronavirus,HIV-1 |
| R52529 |
T27050 |
T97416 |
arg1Of |
microscopy,( |
| R52562 |
T65828 |
T35353 |
arg1Of |
residues,with |
| R52595 |
T35201 |
T66534 |
arg1Of |
reflected,with |
| R526 |
T527 |
T526 |
arg1Of |
constraints,steric |
| R52621 |
T25939 |
T78905 |
arg1Of |
revealed,"," |
| R52677 |
T3262 |
T75132 |
arg1Of |
glycoproteins,coronavirus |
| R527 |
T527 |
T528 |
arg1Of |
constraints,that |
| R52700 |
T68027 |
T62278 |
arg2Of |
level,at |
| R52712 |
T45843 |
T56194 |
arg1Of |
complex,with |
| R52773 |
T76353 |
T21668 |
arg1Of |
evolved,not |
| R52778 |
T39117 |
T85438 |
arg2Of |
hybrid,"," |
| R528 |
T527 |
T529 |
arg1Of |
constraints,prevent |
| R52854 |
T99799 |
T72317 |
arg1Of |
glycoproteins,S |
| R52865 |
T73857 |
T80897 |
arg2Of |
convolved,is |
| R52881 |
T71298 |
T66756 |
arg1Of |
glycoproteins,other |
| R52896 |
T82137 |
T44906 |
arg1Of |
compositions,Glycan |
| R529 |
T530 |
T529 |
arg2Of |
access,prevent |
| R5294 |
T18648 |
T65761 |
arg1Of |
interactions,additional |
| R52971 |
T10175 |
T47018 |
arg1Of |
spectrometry,mass |
| R52995 |
T18623 |
T90503 |
arg1Of |
processed,to |
| R530 |
T530 |
T531 |
arg1Of |
access,of |
| R53035 |
T15993 |
T29715 |
arg1Of |
presence,the |
| R53073 |
T48265 |
T3818 |
arg1Of |
quantities,the |
| R53086 |
T97506 |
T94206 |
arg1Of |
we,showed |
| R531 |
T534 |
T531 |
arg2Of |
enzymes,of |
| R53186 |
T10045 |
T88998 |
arg1Of |
known,as |
| R53198 |
T45911 |
T49036 |
arg1Of |
S,MERS |
| R532 |
T534 |
T532 |
arg1Of |
enzymes,glycan |
| R53259 |
T76130 |
T21250 |
arg1Of |
site,was |
| R53298 |
T94405 |
T98923 |
arg1Of |
model,the |
| R533 |
T534 |
T533 |
arg1Of |
enzymes,processing |
| R53317 |
T3739 |
T39523 |
arg2Of |
glycosylation,of |
| R53320 |
T94093 |
T81366 |
arg2Of |
and,across |
| R53389 |
T38716 |
T12601 |
arg1Of |
note,to |
| R534 |
T530 |
T535 |
arg1Of |
access,to |
| R5341 |
T70323 |
T12704 |
arg1Of |
proteins,S |
| R53447 |
T59672 |
T65945 |
arg2Of |
considered,should |
| R53459 |
T55151 |
T19500 |
arg2Of |
H3N2,with |
| R53479 |
T19223 |
T56739 |
arg1Of |
comparison,to |
| R5348 |
T49936 |
T62735 |
arg1Of |
MERS,and |
| R53490 |
T16685 |
T98764 |
arg1Of |
is,"," |
| R535 |
T537 |
T535 |
arg2Of |
"glycans24,27,28",to |
| R536 |
T537 |
T536 |
arg1Of |
"glycans24,27,28",substrate |
| R53601 |
T69929 |
T55492 |
arg1Of |
whereas,"," |
| R537 |
T523 |
T538 |
arg1Of |
arise,"," |
| R53776 |
T53051 |
T89368 |
arg1Of |
Env,"9,11,53,84–86" |
| R53797 |
T26227 |
T21512 |
arg2Of |
abundance,to |
| R538 |
T523 |
T539 |
arg1Of |
arise,especially |
| R5382 |
T13983 |
T30720 |
arg1Of |
arise,from |
| R53821 |
T32072 |
T34645 |
arg2Of |
5X59,"," |
| R539 |
T545 |
T539 |
arg2Of |
evolved,especially |
| R53928 |
T31925 |
T95730 |
arg2Of |
",",( |
| R53995 |
T57983 |
T2902 |
arg1Of |
"shield54,55",an |
| R540 |
T539 |
T540 |
arg1Of |
especially,when |
| R54019 |
T85969 |
T15501 |
arg1Of |
dynamics,in |
| R54077 |
T70221 |
T22664 |
arg1Of |
proteins,S |
| R541 |
T543 |
T541 |
arg1Of |
glycoprotein,the |
| R54195 |
T90188 |
T66628 |
arg1Of |
map,cryo-EM |
| R542 |
T543 |
T542 |
arg1Of |
glycoprotein,viral |
| R54218 |
T72184 |
T12801 |
arg1Of |
extending,out |
| R54228 |
T96165 |
T8633 |
arg1Of |
residues,amino-acid |
| R54237 |
T19623 |
T95917 |
arg1Of |
to,due |
| R543 |
T543 |
T544 |
arg1Of |
glycoprotein,has |
| R54302 |
T76109 |
T7753 |
arg2Of |
undergoing,would |
| R5435 |
T75405 |
T23602 |
arg2Of |
differences,of |
| R5439 |
T60225 |
T28690 |
arg1Of |
interactions,disallow |
| R54394 |
T39713 |
T83434 |
arg1Of |
they,be |
| R54397 |
T4558 |
T95940 |
arg1Of |
domains,these |
| R544 |
T545 |
T544 |
arg2Of |
evolved,has |
| R5440 |
T75366 |
T27706 |
arg2Of |
presence,and |
| R54442 |
T27983 |
T3044 |
arg2Of |
SARS,on |
| R54454 |
T1970 |
T44006 |
arg1Of |
in,and |
| R54479 |
T68704 |
T3893 |
arg3Of |
exist,shown |
| R545 |
T543 |
T545 |
arg1Of |
glycoprotein,evolved |
| R54511 |
T3893 |
T80149 |
arg1Of |
shown,"," |
| R54519 |
T17113 |
T45227 |
arg1Of |
proteins,were |
| R54575 |
T15037 |
T77189 |
arg1Of |
shield,the |
| R546 |
T547 |
T545 |
arg2Of |
mask,evolved |
| R5462 |
T52475 |
T38716 |
arg2Of |
conservation,note |
| R54626 |
T39186 |
T18701 |
arg1Of |
found,Firstly |
| R54671 |
T57682 |
T50763 |
arg3Of |
),( |
| R54673 |
T38496 |
T6892 |
arg2Of |
shield,likely |
| R547 |
T547 |
T546 |
arg1Of |
mask,to |
| R5473 |
T3337 |
T64033 |
arg1Of |
shield51,( |
| R54761 |
T15412 |
T83531 |
arg2Of |
domains,on |
| R548 |
T543 |
T547 |
arg1Of |
glycoprotein,mask |
| R54851 |
T18734 |
T34570 |
arg2Of |
glycosylation,of |
| R54886 |
T51516 |
T64040 |
arg1Of |
SARS,and |
| R54892 |
T44762 |
T96739 |
arg1Of |
labelled,fluorescently |
| R549 |
T549 |
T547 |
arg2Of |
epitopes,mask |
| R54906 |
T84269 |
T27171 |
arg1Of |
efficacies,Disparate |
| R54914 |
T97839 |
T19232 |
arg1Of |
note,to |
| R54934 |
T30576 |
T6464 |
arg1Of |
S,"," |
| R550 |
T549 |
T548 |
arg1Of |
epitopes,immunogenic |
| R55098 |
T10070 |
T81627 |
arg1Of |
glycans,grouped |
| R551 |
T547 |
T550 |
arg1Of |
mask,with |
| R55106 |
T41472 |
T87865 |
arg1Of |
glycosylation,observed |
| R55130 |
T33036 |
T59397 |
arg2Of |
subunit,upon |
| R55146 |
T86793 |
T90961 |
arg2Of |
epitopes,at |
| R55180 |
T97319 |
T36916 |
arg1Of |
role,a |
| R552 |
T554 |
T550 |
arg2Of |
array,with |
| R5522 |
T46492 |
T30950 |
arg1Of |
and,buried |
| R5523 |
T17645 |
T69288 |
arg1Of |
sites,can |
| R5524 |
T5302 |
T47005 |
arg1Of |
clusters,specific |
| R55289 |
T72680 |
T22467 |
arg1Of |
linked,is |
| R55292 |
T80263 |
T21297 |
arg1Of |
development,of |
| R553 |
T554 |
T551 |
arg1Of |
array,a |
| R5536 |
T1508 |
T80667 |
arg2Of |
boundaries,defines |
| R55385 |
T91715 |
T77670 |
arg1Of |
glycoproteins,viral |
| R55397 |
T51881 |
T7681 |
arg2Of |
least,processed |
| R554 |
T553 |
T552 |
arg1Of |
dense,particularly |
| R55446 |
T40686 |
T3099 |
arg1Of |
produce,to |
| R555 |
T554 |
T553 |
arg1Of |
array,dense |
| R55540 |
T40134 |
T78070 |
arg2Of |
degrees,to |
| R55541 |
T14676 |
T35287 |
arg1Of |
53,virus |
| R55552 |
T39186 |
T74266 |
arg1Of |
found,"," |
| R55556 |
T58389 |
T98213 |
arg1Of |
Investigation,may |
| R55557 |
T82430 |
T2527 |
arg1Of |
combination,simple |
| R556 |
T554 |
T555 |
arg1Of |
array,of |
| R55649 |
T71298 |
T37978 |
arg2Of |
glycoproteins,on |
| R557 |
T557 |
T555 |
arg2Of |
"glycans26,29–34",of |
| R558 |
T557 |
T556 |
arg1Of |
"glycans26,29–34",host-derived |
| R55817 |
T58510 |
T27128 |
arg1Of |
level,high |
| R55821 |
T93961 |
T9745 |
arg1Of |
colored,as |
| R55884 |
T12192 |
T24256 |
arg2Of |
presented,are |
| R559 |
T559 |
T558 |
arg1Of |
access,Restricted |
| R55901 |
T68704 |
T1970 |
arg1Of |
exist,in |
| R55902 |
T46831 |
T85214 |
arg1Of |
SARS,and |
| R55924 |
T19555 |
T55217 |
arg1Of |
importance,The |
| R55949 |
T77922 |
T26521 |
arg1Of |
glycans,on |
| R55953 |
T12192 |
T65467 |
arg1Of |
presented,as |
| R55954 |
T38716 |
T53506 |
arg1Of |
note,is |
| R55957 |
T59935 |
T35748 |
arg2Of |
MERS,on |
| R55972 |
T16685 |
T19500 |
arg1Of |
is,with |
| R55974 |
T69625 |
T49131 |
arg2Of |
study,for |
| R55987 |
T53788 |
T34848 |
arg2Of |
functionality,to |
| R55994 |
T83312 |
T96415 |
arg1Of |
construct,in |
| R560 |
T559 |
T560 |
arg1Of |
access,to |
| R561 |
T563 |
T560 |
arg2Of |
sites,to |
| R5614 |
T28812 |
T79957 |
arg1Of |
phenomenon,been |
| R5616 |
T46694 |
T51798 |
arg3Of |
),( |
| R562 |
T563 |
T561 |
arg1Of |
sites,these |
| R56245 |
T47125 |
T32555 |
arg1Of |
results,The |
| R56289 |
T83020 |
T13036 |
arg1Of |
presence,the |
| R56292 |
T23766 |
T72412 |
arg1Of |
reach,why |
| R56293 |
T20998 |
T44869 |
arg2Of |
regions,in |
| R563 |
T563 |
T562 |
arg1Of |
sites,glycan |
| R56320 |
T59603 |
T11718 |
arg1Of |
values,higher |
| R56386 |
T67026 |
T3893 |
arg2Of |
domains,shown |
| R564 |
T559 |
T564 |
arg1Of |
access,or |
| R56401 |
T69246 |
T23472 |
arg2Of |
domain,in |
| R5643 |
T90997 |
T80023 |
arg1Of |
mass,"," |
| R56486 |
T75405 |
T7434 |
arg1Of |
differences,between |
| R565 |
T565 |
T564 |
arg2Of |
interference,or |
| R56530 |
T56514 |
T9345 |
arg1Of |
population,glycan |
| R56534 |
T30799 |
T43754 |
arg2Of |
and,of |
| R56572 |
T82951 |
T68036 |
arg1Of |
hallmark,the |
| R56590 |
T54715 |
T81576 |
arg2Of |
glycans,underprocessed |
| R566 |
T565 |
T566 |
arg1Of |
interference,with |
| R56658 |
T91843 |
T51816 |
arg1Of |
performed,"," |
| R56677 |
T89162 |
T32044 |
arg1Of |
as,well |
| R567 |
T570 |
T566 |
arg2Of |
or,with |
| R56795 |
T64712 |
T17721 |
arg1Of |
bars,error |
| R568 |
T569 |
T567 |
arg1Of |
surface,surrounding |
| R5680 |
T41193 |
T79801 |
arg2Of |
compositions,ascertain |
| R56810 |
T28395 |
T8259 |
arg1Of |
observed,on |
| R56816 |
T63979 |
T74853 |
arg2Of |
level,on |
| R56819 |
T54008 |
T13224 |
arg1Of |
diversity,amino-acid |
| R56835 |
T11869 |
T28667 |
arg2Of |
sites,of |
| R569 |
T569 |
T568 |
arg1Of |
surface,protein |
| R56933 |
T46492 |
T50177 |
arg1Of |
and,that |
| R56965 |
T28675 |
T66740 |
arg1Of |
sensitive,more |
| R56973 |
T25052 |
T46492 |
arg1Of |
residues,and |
| R570 |
T569 |
T570 |
arg1Of |
surface,or |
| R5701 |
T35106 |
T58672 |
arg1Of |
conserved,on |
| R57022 |
T77506 |
T31301 |
arg2Of |
5X59,and |
| R57066 |
T64807 |
T16967 |
arg1Of |
hemagglutinin,Influenza |
| R57067 |
T73688 |
T54909 |
arg2Of |
effects,of |
| R57079 |
T90997 |
T41537 |
arg1Of |
mass,overall |
| R5709 |
T70745 |
T5519 |
arg1Of |
families,as |
| R571 |
T573 |
T570 |
arg2Of |
residues,or |
| R57152 |
T2696 |
T90378 |
arg1Of |
occluded,that |
| R57155 |
T11314 |
T58293 |
arg1Of |
Env,glycans |
| R572 |
T573 |
T571 |
arg1Of |
residues,neighbouring |
| R57227 |
T79756 |
T40313 |
arg1Of |
diversification,amino-acid |
| R57229 |
T80082 |
T35120 |
arg2Of |
glycopeptides,subjected |
| R57265 |
T22009 |
T47879 |
arg2Of |
conformations52,down |
| R57290 |
T48593 |
T91161 |
arg2Of |
interactions,for |
| R573 |
T573 |
T572 |
arg1Of |
residues,glycan |
| R57330 |
T18666 |
T31589 |
arg1Of |
spectrometry,chromatography-mass |
| R57363 |
T60289 |
T75223 |
arg1Of |
We,observe |
| R574 |
T564 |
T574 |
arg1Of |
or,can |
| R57447 |
T15145 |
T60855 |
arg2Of |
contrast,In |
| R57469 |
T40337 |
T1822 |
arg2Of |
surprising,is |
| R575 |
T575 |
T574 |
arg2Of |
render,can |
| R57536 |
T33045 |
T57945 |
arg2Of |
quantification,summarise |
| R57557 |
T52754 |
T33039 |
arg2Of |
MERS,of |
| R57572 |
T28685 |
T14464 |
arg1Of |
proteins,I |
| R57589 |
T72173 |
T72299 |
arg1Of |
SARS,and |
| R57595 |
T40473 |
T81627 |
arg2Of |
according,grouped |
| R576 |
T564 |
T575 |
arg1Of |
or,render |
| R57657 |
T60933 |
T67945 |
arg2Of |
illustrated,is |
| R57681 |
T8708 |
T8441 |
arg1Of |
importance,in |
| R577 |
T578 |
T575 |
arg2Of |
enzymes,render |
| R57707 |
T2410 |
T35106 |
arg2Of |
sites,conserved |
| R57723 |
T76564 |
T45093 |
modOf |
performed,to |
| R57764 |
T6621 |
T32139 |
arg1Of |
contribute,likely |
| R57790 |
T61369 |
T65163 |
arg2Of |
ratio,of |
| R578 |
T578 |
T576 |
arg1Of |
enzymes,glycan |
| R57807 |
T29035 |
T64910 |
arg2Of |
Comparison,below. |
| R57832 |
T10006 |
T72299 |
arg2Of |
SARS-CoV-2,and |
| R579 |
T578 |
T577 |
arg1Of |
enzymes,processing |
| R57902 |
T37933 |
T36713 |
arg1Of |
and,"," |
| R57960 |
T86335 |
T22368 |
arg1Of |
glycan,25 |
| R57966 |
T3442 |
T14224 |
arg3Of |
),( |
| R57987 |
T46529 |
T15001 |
arg2Of |
S1,on |
| R580 |
T578 |
T579 |
arg1Of |
enzymes,ineffective |
| R58022 |
T26975 |
T50401 |
arg2Of |
network,to |
| R58028 |
T29672 |
T32530 |
arg1Of |
datasets,are |
| R58051 |
T52131 |
T31210 |
arg2Of |
N-glycans,of |
| R58091 |
T42803 |
T98608 |
arg1Of |
Fig. 3,SI |
| R581 |
T579 |
T580 |
arg1Of |
ineffective,in |
| R58120 |
T7879 |
T43250 |
arg1Of |
structure,results |
| R58191 |
T53941 |
T13950 |
arg1Of |
SOSIP.664,Env |
| R58193 |
T11359 |
T63374 |
arg1Of |
consist,of |
| R582 |
T582 |
T580 |
arg2Of |
"regions27,28,35",in |
| R58201 |
T26975 |
T69150 |
arg1Of |
network,extensive |
| R58211 |
T84168 |
T41531 |
arg1Of |
glycans,N-linked |
| R58230 |
T1909 |
T61501 |
arg1Of |
",","," |
| R58232 |
T17681 |
T49759 |
arg1Of |
candidates,are |
| R58277 |
T82870 |
T51016 |
arg1Of |
protein,the |
| R583 |
T582 |
T581 |
arg1Of |
"regions27,28,35",specific |
| R58315 |
T94581 |
T64033 |
arg3Of |
),( |
| R58316 |
T36644 |
T11498 |
arg2Of |
ascertained,were |
| R58325 |
T53169 |
T48490 |
arg1Of |
GPC,LASV |
| R58336 |
T58389 |
T89551 |
arg1Of |
Investigation,offer |
| R58371 |
T38496 |
T46550 |
arg1Of |
shield,that |
| R58398 |
T1949 |
T59041 |
arg1Of |
diversity,per |
| R584 |
T584 |
T583 |
arg1Of |
processing,Glycan |
| R58419 |
T79406 |
T92544 |
arg2Of |
0.45,of |
| R58427 |
T40801 |
T27804 |
arg1Of |
are,"," |
| R58435 |
T58945 |
T50799 |
arg1Of |
number,the |
| R5844 |
T12473 |
T30751 |
arg2Of |
reduced,was |
| R58449 |
T80844 |
T50530 |
arg2Of |
networks,lack |
| R5847 |
T17336 |
T85225 |
arg2Of |
are,Although |
| R585 |
T584 |
T585 |
arg1Of |
processing,on |
| R58533 |
T51449 |
T66872 |
arg1Of |
proteins,seven |
| R58586 |
T12652 |
T4328 |
arg2Of |
residues,exposed |
| R586 |
T587 |
T585 |
arg2Of |
glycoproteins,on |
| R58609 |
T70460 |
T83202 |
arg1Of |
clustering,glycan |
| R58623 |
T95555 |
T21512 |
arg1Of |
contribute,to |
| R58633 |
T49812 |
T54764 |
arg2Of |
particles,from |
| R58664 |
T53545 |
T22648 |
arg1Of |
enzymes,glycan |
| R58669 |
T18888 |
T53506 |
arg2Of |
interesting,is |
| R587 |
T587 |
T586 |
arg1Of |
glycoproteins,soluble |
| R58702 |
T47078 |
T81728 |
arg1Of |
possesses,compared |
| R58705 |
T19314 |
T8259 |
arg2Of |
MERS,on |
| R58717 |
T89591 |
T64910 |
arg1Of |
shown,below. |
| R58754 |
T79677 |
T52275 |
arg1Of |
maps,reveal |
| R58770 |
T53788 |
T35971 |
arg1Of |
functionality,"," |
| R58772 |
T15651 |
T48291 |
arg1Of |
resolution,poor |
| R58777 |
T30576 |
T72214 |
arg1Of |
S,( |
| R5878 |
T50969 |
T51721 |
arg1Of |
limit,"," |
| R58787 |
T72037 |
T58264 |
arg1Of |
most,competent |
| R588 |
T584 |
T588 |
arg1Of |
processing,has |
| R5883 |
T86793 |
T69090 |
arg2Of |
epitopes,known |
| R58840 |
T26380 |
T91154 |
arg1Of |
value,a |
| R58873 |
T48265 |
T64768 |
arg2Of |
quantities,represent |
| R58879 |
T68204 |
T48812 |
arg2Of |
measured,are |
| R589 |
T591 |
T588 |
arg2Of |
shown,has |
| R58922 |
T81038 |
T50998 |
arg2Of |
Man5GlcNAc2,to |
| R5899 |
T46270 |
T13544 |
arg2Of |
models,of |
| R58997 |
T66915 |
T49578 |
arg1Of |
and,"," |
| R58999 |
T39891 |
T35333 |
arg1Of |
core,central |
| R590 |
T591 |
T589 |
arg1Of |
shown,also |
| R59003 |
T16685 |
T66750 |
arg1Of |
is,compared |
| R59010 |
T48849 |
T57102 |
arg2Of |
ecology,in |
| R59063 |
T59935 |
T9158 |
arg1Of |
MERS,a |
| R59081 |
T17681 |
T79396 |
arg1Of |
candidates,fail |
| R59094 |
T12587 |
T26996 |
arg1Of |
environment,the |
| R591 |
T584 |
T590 |
arg1Of |
processing,been |
| R59119 |
T35287 |
T87593 |
arg1Of |
virus,S41 |
| R59125 |
T49977 |
T70719 |
arg1Of |
responses,immune |
| R59136 |
T82430 |
T32469 |
arg1Of |
combination,of |
| R5916 |
T24392 |
T77635 |
arg2Of |
MERS,on |
| R592 |
T591 |
T590 |
arg2Of |
shown,been |
| R59202 |
T58379 |
T85598 |
arg1Of |
target,the |
| R59233 |
T40498 |
T83531 |
arg1Of |
lack,on |
| R593 |
T584 |
T591 |
arg2Of |
processing,shown |
| R59320 |
T10070 |
T18896 |
arg1Of |
glycans,complex |
| R59338 |
T86385 |
T80173 |
arg2Of |
4ZMJ,"," |
| R59353 |
T99530 |
T57258 |
arg1Of |
analysis,of |
| R59358 |
T33012 |
T31397 |
arg1Of |
Victoria,2011 |
| R594 |
T593 |
T591 |
arg3Of |
be,shown |
| R59455 |
T76353 |
T10053 |
arg2Of |
evolved,speculate |
| R595 |
T593 |
T592 |
arg1Of |
be,to |
| R59501 |
T74512 |
T22927 |
arg2Of |
PNGs,( |
| R59560 |
T40157 |
T77923 |
arg2Of |
continually,than |
| R596 |
T584 |
T593 |
arg1Of |
processing,be |
| R59613 |
T18714 |
T37792 |
arg1Of |
shield,of |
| R59653 |
T84269 |
T39330 |
arg1Of |
efficacies,of |
| R59667 |
T66936 |
T81346 |
arg1Of |
number,The |
| R597 |
T596 |
T593 |
arg2Of |
reporter,be |
| R59703 |
T85969 |
T63261 |
arg1Of |
dynamics,leads |
| R59746 |
T82481 |
T93743 |
arg1Of |
subunit,to |
| R59757 |
T50969 |
T94812 |
arg1Of |
limit,that |
| R598 |
T596 |
T594 |
arg1Of |
reporter,a |
| R59802 |
T20048 |
T56668 |
arg1Of |
response,the |
| R59810 |
T99242 |
T67844 |
arg1Of |
head,of |
| R59811 |
T92110 |
T70681 |
arg1Of |
glycans,N-linked |
| R59857 |
T37762 |
T71933 |
arg1Of |
additions,glycan |
| R59877 |
T17645 |
T39985 |
arg2Of |
sites,incorporated |
| R599 |
T596 |
T595 |
arg1Of |
reporter,strong |
| R59919 |
T40590 |
T34685 |
arg1Of |
area,and |
| R59937 |
T9415 |
T52453 |
arg2Of |
variability,with |
| R59957 |
T20048 |
T51090 |
arg1Of |
response,to |
| R600 |
T596 |
T597 |
arg1Of |
reporter,of |
| R60004 |
T23766 |
T92394 |
arg1Of |
reach,not |
| R60028 |
T16399 |
T41174 |
arg2Of |
b,"," |
| R60041 |
T20968 |
T22989 |
arg1Of |
and,"," |
| R601 |
T600 |
T597 |
arg2Of |
architecture,of |
| R60137 |
T20910 |
T72375 |
arg1Of |
antibodies,neutralizing |
| R602 |
T600 |
T598 |
arg1Of |
architecture,native-like |
| R60211 |
T68543 |
T61338 |
arg1Of |
glycoproteins,All |
| R60221 |
T28749 |
T56558 |
arg1Of |
structures,Using |
| R603 |
T600 |
T599 |
arg1Of |
architecture,protein |
| R60328 |
T55295 |
T77211 |
arg1Of |
proteins,I |
| R60366 |
T25304 |
T6148 |
arg2Of |
sequences,using |
| R604 |
T591 |
T601 |
arg1Of |
shown,and |
| R60416 |
T99373 |
T65467 |
arg2Of |
surfaces,as |
| R60420 |
T28528 |
T53426 |
arg2Of |
measure,as |
| R60460 |
T87593 |
T79382 |
arg1Of |
S41,and |
| R605 |
T616 |
T601 |
arg2Of |
mimic,and |
| R60505 |
T94035 |
T93804 |
arg1Of |
and,"," |
| R60567 |
T66921 |
T48812 |
arg1Of |
they,are |
| R606 |
T616 |
T602 |
arg1Of |
mimic,thus |
| R60603 |
T13499 |
T59995 |
arg1Of |
differences,in |
| R60609 |
T38215 |
T49022 |
arg1Of |
rates,higher |
| R60619 |
T11163 |
T70780 |
arg2Of |
cells,in |
| R607 |
T604 |
T603 |
arg1Of |
integrity36–38,immunogen |
| R60748 |
T50771 |
T45372 |
arg1Of |
it,tempting |
| R60765 |
T14682 |
T76353 |
arg1Of |
MERS,evolved |
| R60780 |
T37031 |
T11037 |
arg1Of |
We,speculate |
| R60786 |
T35915 |
T38149 |
arg1Of |
structure,of |
| R60789 |
T15627 |
T64574 |
arg1Of |
nanobodies,which |
| R608 |
T606 |
T605 |
arg1Of |
and,; |
| R609 |
T604 |
T606 |
arg1Of |
integrity36–38,and |
| R60972 |
T49009 |
T80667 |
arg1Of |
structure,defines |
| R60976 |
T93024 |
T49839 |
arg3Of |
),( |
| R60996 |
T89313 |
T61578 |
arg1Of |
much,of |
| R60997 |
T88004 |
T67434 |
arg2Of |
mutants,of |
| R610 |
T608 |
T606 |
arg2Of |
processing,and |
| R61028 |
T96423 |
T11954 |
arg1Of |
spikes,coronavirus |
| R6106 |
T94857 |
T83825 |
arg2Of |
Mapping,indicate |
| R611 |
T608 |
T607 |
arg1Of |
processing,glycan |
| R61108 |
T68440 |
T57335 |
arg2Of |
example,For |
| R6112 |
T38716 |
T18888 |
arg1Of |
note,interesting |
| R61128 |
T66049 |
T52094 |
arg2Of |
shield,in |
| R61132 |
T7541 |
T22232 |
arg1Of |
S,SARS |
| R61179 |
T16712 |
T82163 |
arg2Of |
domains,of |
| R612 |
T606 |
T609 |
arg1Of |
and,on |
| R61214 |
T88390 |
T27490 |
arg1Of |
glycans,are |
| R61258 |
T85671 |
T75169 |
arg2Of |
illustrated,is |
| R613 |
T613 |
T609 |
arg2Of |
candidate,on |
| R61334 |
T56514 |
T52338 |
arg1Of |
population,in |
| R61336 |
T75554 |
T19065 |
arg1Of |
spikes,"," |
| R614 |
T613 |
T610 |
arg1Of |
candidate,a |
| R61408 |
T31427 |
T47095 |
arg2Of |
proteins,reduced |
| R61420 |
T46703 |
T30395 |
arg1Of |
Cryo-EM,captures |
| R61425 |
T84496 |
T37174 |
arg1Of |
S,SARS |
| R61431 |
T81494 |
T44486 |
arg1Of |
resulting,in |
| R61444 |
T17162 |
T49747 |
arg1Of |
colored,according |
| R61463 |
T79412 |
T92980 |
arg1Of |
is,given |
| R61464 |
T33263 |
T59798 |
arg2Of |
and,on |
| R61476 |
T62928 |
T83472 |
arg1Of |
glycans,oligomannose-type |
| R615 |
T613 |
T611 |
arg1Of |
candidate,successful |
| R61523 |
T6621 |
T58427 |
arg1Of |
contribute,to |
| R61542 |
T12473 |
T88293 |
arg2Of |
reduced,when |
| R61550 |
T72037 |
T22099 |
arg1Of |
most,are |
| R61571 |
T10175 |
T31210 |
arg1Of |
spectrometry,of |
| R61595 |
T46492 |
T59632 |
arg1Of |
and,unable |
| R616 |
T613 |
T612 |
arg1Of |
candidate,immunogen |
| R61674 |
T15037 |
T22984 |
arg1Of |
shield,SARS |
| R61681 |
T65633 |
T71210 |
arg1Of |
We,hypothesized |
| R617 |
T606 |
T614 |
arg1Of |
and,should |
| R61784 |
T84041 |
T30414 |
arg2Of |
Fig. 6,( |
| R6179 |
T21366 |
T22927 |
arg1Of |
sites,( |
| R618 |
T616 |
T614 |
arg2Of |
mimic,should |
| R61821 |
T17864 |
T33234 |
arg2Of |
processing,of |
| R61866 |
T1822 |
T94718 |
arg1Of |
is,as |
| R619 |
T616 |
T615 |
arg1Of |
mimic,therefore |
| R61961 |
T53788 |
T5062 |
arg1Of |
functionality,be |
| R620 |
T606 |
T616 |
arg1Of |
and,mimic |
| R62064 |
T2440 |
T44594 |
arg1Of |
glycoproteins,a |
| R62080 |
T8574 |
T5765 |
arg2Of |
highlighted,were |
| R621 |
T625 |
T616 |
arg2Of |
features,mimic |
| R62100 |
T79756 |
T38057 |
arg2Of |
diversification,of |
| R62113 |
T28528 |
T85566 |
arg1Of |
measure,a |
| R62161 |
T75213 |
T29294 |
arg1Of |
peptide,"," |
| R62165 |
T34685 |
T92980 |
arg2Of |
and,given |
| R62166 |
T96165 |
T75342 |
arg1Of |
residues,solvent-accessible |
| R622 |
T616 |
T617 |
arg1Of |
mimic,"," |
| R62239 |
T94571 |
T49839 |
arg1Of |
"procainamide24,45,53",( |
| R62271 |
T49864 |
T25055 |
arg1Of |
glycans,and |
| R623 |
T619 |
T618 |
arg1Of |
closely,as |
| R62312 |
T38606 |
T35666 |
arg1Of |
GPC,which |
| R6232 |
T72703 |
T32445 |
arg1Of |
levels,greater |
| R62327 |
T83312 |
T36617 |
arg1Of |
construct,a |
| R62340 |
T80844 |
T81018 |
arg1Of |
networks,are |
| R62361 |
T29672 |
T95444 |
arg1Of |
datasets,available |
| R624 |
T616 |
T619 |
arg1Of |
mimic,closely |
| R62409 |
T83381 |
T82158 |
arg1Of |
glycosylation,extensive |
| R62464 |
T35287 |
T14224 |
arg1Of |
virus,( |
| R625 |
T619 |
T620 |
arg1Of |
closely,as |
| R62502 |
T97769 |
T59510 |
arg1Of |
nextstrain61,( |
| R62547 |
T32345 |
T33520 |
arg1Of |
environment,of |
| R62598 |
T87240 |
T62278 |
arg1Of |
visualised,at |
| R626 |
T621 |
T620 |
arg2Of |
possible,as |
| R62630 |
T73114 |
T38418 |
arg1Of |
compare,directly |
| R627 |
T616 |
T622 |
arg1Of |
mimic,"," |
| R62725 |
T84653 |
T55443 |
arg1Of |
proteins,Viral |
| R62729 |
T39465 |
T51236 |
arg2Of |
“shields”,of |
| R628 |
T625 |
T623 |
arg1Of |
features,the |
| R62810 |
T43357 |
T59397 |
arg1Of |
pressure,upon |
| R62818 |
T74546 |
T93956 |
arg2Of |
investigated,have |
| R62847 |
T91691 |
T94206 |
arg2Of |
how,showed |
| R62864 |
T37921 |
T57424 |
arg2Of |
glycans,with |
| R629 |
T625 |
T624 |
arg1Of |
features,structural |
| R62925 |
T54044 |
T91196 |
arg1Of |
evasion,immune |
| R62926 |
T76564 |
T7134 |
arg1Of |
performed,subsequently |
| R62985 |
T19555 |
T90413 |
arg1Of |
importance,be |
| R630 |
T625 |
T626 |
arg2Of |
features,observed |
| R6303 |
T90192 |
T12725 |
arg1Of |
number,divided |
| R63032 |
T31301 |
T42948 |
arg1Of |
and,respectively |
| R63038 |
T13983 |
T10659 |
arg1Of |
arise,as |
| R63070 |
T43199 |
T26807 |
arg2Of |
diversity,observed |
| R63082 |
T80844 |
T70160 |
arg1Of |
networks,glycan |
| R631 |
T626 |
T627 |
arg1Of |
observed,on |
| R63130 |
T72317 |
T91868 |
arg1Of |
S,SARS |
| R63181 |
T26958 |
T7859 |
arg2Of |
antibodies8,neutralising |
| R632 |
T630 |
T627 |
arg2Of |
"virus39,40",on |
| R6327 |
T88367 |
T51085 |
arg1Of |
levels,differential |
| R63270 |
T59243 |
T48816 |
arg2Of |
SARS,and |
| R63284 |
T83312 |
T53941 |
arg1Of |
construct,SOSIP.664 |
| R633 |
T630 |
T628 |
arg1Of |
"virus39,40",the |
| R63314 |
T24762 |
T46241 |
arg1Of |
glycoprotein,the |
| R63316 |
T6621 |
T85630 |
arg1Of |
contribute,"," |
| R634 |
T630 |
T629 |
arg1Of |
"virus39,40",native |
| R63445 |
T8574 |
T92418 |
arg1Of |
highlighted,Furthermore |
| R635 |
T652 |
T631 |
arg1Of |
and,Here |
| R636 |
T652 |
T632 |
arg1Of |
and,"," |
| R63626 |
T21664 |
T86817 |
arg1Of |
",","," |
| R637 |
T633 |
T634 |
arg1Of |
we,provide |
| R63756 |
T63979 |
T53700 |
arg1Of |
level,residue-specific |
| R63791 |
T66354 |
T67807 |
arg1Of |
shielding,the |
| R638 |
T638 |
T634 |
arg2Of |
analyses,provide |
| R639 |
T638 |
T635 |
arg1Of |
analyses,global |
| R6390 |
T94857 |
T13865 |
arg1Of |
Mapping,of |
| R63943 |
T66049 |
T24478 |
arg1Of |
shield,effective |
| R63988 |
T1830 |
T4468 |
arg1Of |
hinders,"," |
| R640 |
T635 |
T636 |
arg1Of |
global,and |
| R64002 |
T72369 |
T18378 |
arg1Of |
substitutions,( |
| R641 |
T637 |
T636 |
arg2Of |
site-specific,and |
| R64110 |
T88747 |
T37978 |
arg1Of |
observed,on |
| R6412 |
T27017 |
T59510 |
arg2Of |
https,( |
| R64143 |
T42122 |
T51626 |
arg2Of |
signal,to |
| R64157 |
T97839 |
T15902 |
arg1Of |
note,is |
| R64184 |
T91997 |
T72208 |
arg2Of |
SARS,of |
| R642 |
T638 |
T637 |
arg1Of |
analyses,site-specific |
| R64222 |
T26744 |
T52698 |
arg2Of |
viruses,of |
| R64246 |
T20023 |
T60633 |
arg1Of |
reservoirs,natural |
| R6426 |
T15042 |
T47642 |
arg3Of |
),( |
| R64275 |
T99013 |
T67538 |
arg1Of |
Fig. 4,SI |
| R64284 |
T33026 |
T67409 |
arg1Of |
glycans,released |
| R643 |
T638 |
T639 |
arg1Of |
analyses,of |
| R64301 |
T72051 |
T49737 |
arg1Of |
populations,complex-type |
| R64305 |
T80559 |
T61778 |
arg2Of |
example,For |
| R644 |
T641 |
T639 |
arg2Of |
glycosylation,of |
| R64406 |
T53788 |
T92413 |
arg1Of |
functionality,of |
| R6442 |
T63261 |
T50401 |
arg1Of |
leads,to |
| R6444 |
T80082 |
T20638 |
arg1Of |
glycopeptides,were |
| R64448 |
T49099 |
T83248 |
arg1Of |
domain,N-terminal |
| R645 |
T641 |
T640 |
arg1Of |
glycosylation,N-linked |
| R64546 |
T43156 |
T11597 |
arg1Of |
intervals,the |
| R64553 |
T40276 |
T86408 |
arg1Of |
found,in |
| R646 |
T634 |
T642 |
arg1Of |
provide,on |
| R64614 |
T1963 |
T3743 |
arg1Of |
implicated,Importantly |
| R64641 |
T5164 |
T60933 |
arg2Of |
modelling,illustrated |
| R64648 |
T52910 |
T34630 |
arg1Of |
and,are |
| R647 |
T647 |
T642 |
arg2Of |
and,on |
| R64703 |
T43156 |
T18198 |
arg1Of |
intervals,highest |
| R648 |
T644 |
T643 |
arg1Of |
SARS,soluble |
| R64810 |
T75209 |
T86959 |
arg1Of |
ectodomain52,2P |
| R64817 |
T15004 |
T1634 |
arg1Of |
region,this |
| R64829 |
T30776 |
T73014 |
arg1Of |
S,( |
| R649 |
T644 |
T645 |
arg1Of |
SARS,"," |
| R64905 |
T64331 |
T42940 |
arg2Of |
ratios,had |
| R6499 |
T11435 |
T35149 |
arg1Of |
advantage,a |
| R64991 |
T38215 |
T48007 |
arg1Of |
rates,of |
| R650 |
T646 |
T645 |
arg2Of |
MERS,"," |
| R65018 |
T56273 |
T13124 |
arg1Of |
map,cryo-EM |
| R65034 |
T80657 |
T3932 |
arg1Of |
protein,I |
| R6504 |
T10907 |
T31145 |
arg1Of |
Hybrid,& |
| R65049 |
T4934 |
T30435 |
arg1Of |
responses,targeted |
| R6505 |
T53788 |
T19398 |
arg1Of |
functionality,would |
| R65072 |
T99864 |
T53301 |
arg1Of |
5X59,PDB |
| R65080 |
T38496 |
T82041 |
arg2Of |
shield,would |
| R651 |
T645 |
T647 |
arg1Of |
",",and |
| R65134 |
T75718 |
T53208 |
arg1Of |
mapping,on |
| R65182 |
T38777 |
T20732 |
arg1Of |
densities,shield |
| R65191 |
T73121 |
T64380 |
arg1Of |
whereas,that |
| R65192 |
T52424 |
T33530 |
arg1Of |
Comparison,of |
| R652 |
T651 |
T647 |
arg2Of |
glycoproteins,and |
| R653 |
T651 |
T648 |
arg1Of |
glycoproteins,HKU1 |
| R65335 |
T42677 |
T38584 |
arg2Of |
distribution,regarding |
| R65398 |
T38606 |
T40144 |
arg2Of |
GPC,from |
| R654 |
T651 |
T649 |
arg1Of |
glycoproteins,CoV |
| R65480 |
T64096 |
T70981 |
arg1Of |
this,due |
| R655 |
T651 |
T650 |
arg1Of |
glycoproteins,S |
| R65513 |
T34685 |
T59451 |
arg1Of |
and,the |
| R65530 |
T10448 |
T93438 |
arg1Of |
are,without |
| R65536 |
T48265 |
T96495 |
arg1Of |
quantities,of |
| R65540 |
T95182 |
T60590 |
arg1Of |
",",that |
| R65597 |
T93319 |
T43420 |
arg2Of |
domains,and |
| R656 |
T634 |
T652 |
arg1Of |
provide,and |
| R65600 |
T39941 |
T50763 |
arg1Of |
genes,( |
| R65608 |
T60790 |
T58919 |
arg2Of |
domains,and |
| R65614 |
T90192 |
T62752 |
arg1Of |
number,of |
| R65623 |
T37597 |
T88916 |
arg1Of |
data,only |
| R6563 |
T68704 |
T47879 |
arg1Of |
exist,down |
| R65669 |
T40780 |
T66900 |
arg2Of |
clusters,to |
| R657 |
T653 |
T652 |
arg2Of |
reveal,and |
| R65728 |
T84653 |
T43155 |
arg1Of |
proteins,are |
| R65730 |
T36034 |
T38496 |
arg2Of |
epitopes,shield |
| R65742 |
T26227 |
T61001 |
arg1Of |
abundance,mannose |
| R658 |
T633 |
T653 |
arg1Of |
we,reveal |
| R65830 |
T64906 |
T93681 |
arg1Of |
H1N1,HAs |
| R65839 |
T76172 |
T86648 |
arg2Of |
immunization62–65,or |
| R65847 |
T30265 |
T63067 |
arg2Of |
reproduced,were |
| R65867 |
T51812 |
T21664 |
arg1Of |
trypsin,"," |
| R659 |
T655 |
T653 |
arg2Of |
heterogeneity,reveal |
| R65901 |
T68704 |
T33461 |
arg1Of |
exist,to |
| R65942 |
T72051 |
T78484 |
arg1Of |
populations,glycan |
| R65951 |
T75554 |
T68142 |
arg1Of |
spikes,would |
| R65982 |
T74525 |
T27935 |
arg1Of |
but,"," |
| R65984 |
T41472 |
T64701 |
arg1Of |
glycosylation,the |
| R660 |
T655 |
T654 |
arg1Of |
heterogeneity,extensive |
| R66003 |
T99830 |
T26453 |
arg1Of |
hindered,sterically |
| R66006 |
T2204 |
T69932 |
arg2Of |
sites,define |
| R6605 |
T10370 |
T92947 |
arg1Of |
density,glycan |
| R66074 |
T99824 |
T75223 |
arg2Of |
density,observe |
| R661 |
T655 |
T656 |
arg1Of |
heterogeneity,"," |
| R66138 |
T7534 |
T37469 |
arg2Of |
limits,and |
| R66153 |
T56236 |
T84889 |
arg2Of |
b,"," |
| R66179 |
T36278 |
T38160 |
arg1Of |
S,"," |
| R66182 |
T16113 |
T98169 |
arg1Of |
panel,: |
| R662 |
T655 |
T657 |
arg1Of |
heterogeneity,ranging |
| R6622 |
T92070 |
T48648 |
arg1Of |
proteins,MERS |
| R663 |
T657 |
T658 |
arg1Of |
ranging,from |
| R66350 |
T43748 |
T42839 |
arg2Of |
structure,building |
| R66356 |
T31010 |
T73372 |
arg1Of |
correlation,A |
| R66372 |
T12725 |
T73735 |
arg2Of |
divided,was |
| R664 |
T660 |
T658 |
arg2Of |
glycans,from |
| R6643 |
T57392 |
T93684 |
arg1Of |
information,be |
| R66468 |
T41135 |
T52094 |
arg1Of |
resulting,in |
| R665 |
T660 |
T659 |
arg1Of |
glycans,oligomannose-type |
| R666 |
T655 |
T661 |
arg1Of |
heterogeneity,to |
| R66604 |
T31301 |
T29063 |
arg2Of |
and,( |
| R66605 |
T52033 |
T63553 |
arg2Of |
proteases,of |
| R66611 |
T49153 |
T64021 |
arg2Of |
density,blurred |
| R6662 |
T64538 |
T59288 |
arg1Of |
notion,is |
| R66651 |
T73192 |
T73414 |
arg1Of |
result,that |
| R667 |
T664 |
T661 |
arg2Of |
glycosylation,to |
| R668 |
T664 |
T662 |
arg1Of |
glycosylation,highly-processed |
| R66839 |
T98451 |
T76352 |
arg1Of |
diversities,amino-acid |
| R669 |
T664 |
T663 |
arg1Of |
glycosylation,complex-type |
| R66915 |
T54061 |
T9629 |
arg2Of |
proteins,and |
| R66917 |
T88390 |
T93818 |
arg1Of |
glycans,The |
| R66919 |
T76860 |
T87041 |
arg2Of |
glycans,N-linked |
| R66924 |
T99824 |
T59798 |
arg1Of |
density,on |
| R66944 |
T11869 |
T12092 |
arg1Of |
sites,22 |
| R66989 |
T81945 |
T17293 |
arg1Of |
MERS,and |
| R670 |
T667 |
T665 |
arg1Of |
mapping,The |
| R67033 |
T66915 |
T34488 |
arg1Of |
and,( |
| R67041 |
T56105 |
T54764 |
arg1Of |
derived,from |
| R67045 |
T80657 |
T27555 |
arg2Of |
protein,is |
| R67091 |
T80023 |
T28342 |
arg1Of |
",",and |
| R671 |
T667 |
T666 |
arg1Of |
mapping,structural |
| R67128 |
T43073 |
T26917 |
arg1Of |
overlaid,simulated |
| R67130 |
T69826 |
T87240 |
arg2Of |
glycoprotein,visualised |
| R67157 |
T54008 |
T93591 |
arg2Of |
diversity,elevated |
| R67171 |
T55295 |
T21676 |
arg1Of |
proteins,fusion |
| R672 |
T667 |
T668 |
arg1Of |
mapping,of |
| R67211 |
T77800 |
T76427 |
arg1Of |
analysis,Bioinformatic |
| R67273 |
T30887 |
T77108 |
arg1Of |
are,"," |
| R67277 |
T97014 |
T51212 |
arg1Of |
response,host |
| R67284 |
T75679 |
T74428 |
arg1Of |
sequences,S |
| R673 |
T669 |
T668 |
arg2Of |
glycans,of |
| R67326 |
T43357 |
T38229 |
arg1Of |
pressure,immune |
| R6736 |
T58945 |
T17558 |
arg1Of |
number,divided |
| R67380 |
T42487 |
T38057 |
arg1Of |
evaluation,of |
| R67385 |
T2696 |
T21250 |
arg2Of |
occluded,was |
| R674 |
T669 |
T670 |
arg1Of |
glycans,of |
| R67400 |
T15037 |
T97881 |
arg2Of |
shield,of |
| R67426 |
T48129 |
T16400 |
arg1Of |
IgG,serum |
| R67428 |
T66804 |
T80348 |
arg1Of |
surface,which |
| R67493 |
T36034 |
T43430 |
arg1Of |
epitopes,that |
| R675 |
T673 |
T670 |
arg2Of |
proteins,of |
| R67521 |
T25542 |
T29000 |
arg1Of |
coverage,sparser |
| R67544 |
T25653 |
T72137 |
arg2Of |
SARS-CoV-2,from |
| R676 |
T673 |
T671 |
arg1Of |
proteins,trimeric |
| R67642 |
T15037 |
T32877 |
arg1Of |
shield,glycan |
| R67665 |
T14676 |
T9596 |
arg2Of |
53,of |
| R67688 |
T51996 |
T78773 |
arg2Of |
calculated,were |
| R677 |
T673 |
T672 |
arg1Of |
proteins,S |
| R67744 |
T46398 |
T12832 |
arg1Of |
were,Although |
| R67783 |
T8069 |
T66117 |
arg1Of |
glycan28,the |
| R67792 |
T58510 |
T94740 |
arg1Of |
level,contour |
| R67799 |
T59734 |
T82162 |
arg1Of |
constraints,as |
| R678 |
T667 |
T674 |
arg1Of |
mapping,revealed |
| R6781 |
T66804 |
T27513 |
arg1Of |
surface,and |
| R67827 |
T10989 |
T79574 |
arg1Of |
"response21,31",host |
| R67847 |
T61476 |
T43495 |
arg1Of |
residues,of |
| R679 |
T680 |
T674 |
arg2Of |
contribute,revealed |
| R67918 |
T34663 |
T28338 |
arg1Of |
observed,on |
| R6796 |
T85214 |
T29063 |
arg1Of |
and,( |
| R67963 |
T54943 |
T78450 |
arg1Of |
coronavirus,this |
| R680 |
T680 |
T675 |
arg1Of |
contribute,that |
| R6800 |
T2450 |
T43383 |
arg1Of |
Env,HIV-1 |
| R68081 |
T78585 |
T27968 |
arg1Of |
2.82,for |
| R681 |
T676 |
T677 |
arg1Of |
some,of |
| R68137 |
T88882 |
T23715 |
arg2Of |
subject,are |
| R68158 |
T15422 |
T10462 |
arg1Of |
surface,the |
| R682 |
T679 |
T677 |
arg2Of |
glycans,of |
| R68204 |
T3893 |
T10724 |
modOf |
shown,leading |
| R683 |
T679 |
T678 |
arg1Of |
glycans,these |
| R68310 |
T36034 |
T42643 |
arg1Of |
epitopes,are |
| R68327 |
T68539 |
T70877 |
arg1Of |
glycans,oligomannose-type |
| R68351 |
T40498 |
T81866 |
arg1Of |
lack,of |
| R684 |
T676 |
T680 |
arg1Of |
some,contribute |
| R68437 |
T77577 |
T6892 |
arg1Of |
observed,likely |
| R68459 |
T90192 |
T71326 |
arg2Of |
number,by |
| R68476 |
T10370 |
T81164 |
arg1Of |
density,shield |
| R68490 |
T14361 |
T7384 |
arg1Of |
outbreak,each |
| R685 |
T680 |
T681 |
arg1Of |
contribute,to |
| R68581 |
T29096 |
T16612 |
arg1Of |
modifications,post-translational |
| R68588 |
T61586 |
T97416 |
arg3Of |
),( |
| R68593 |
T81297 |
T37643 |
arg2Of |
surface,of |
| R686 |
T683 |
T681 |
arg2Of |
formation,to |
| R6860 |
T10324 |
T58779 |
arg1Of |
ratios,dN/dS |
| R68611 |
T60774 |
T35369 |
arg1Of |
sites,glycosylation |
| R68632 |
T70323 |
T33888 |
arg1Of |
proteins,( |
| R6866 |
T69286 |
T16556 |
arg2Of |
calculated,was |
| R68677 |
T35584 |
T85948 |
arg2Of |
functionality,perturbing |
| R687 |
T683 |
T682 |
arg1Of |
formation,the |
| R6872 |
T91463 |
T37758 |
arg1Of |
coming,from |
| R688 |
T683 |
T684 |
arg1Of |
formation,of |
| R68812 |
T78881 |
T64135 |
arg1Of |
4O5N,"," |
| R68851 |
T2961 |
T14475 |
arg1Of |
had,"," |
| R68855 |
T32211 |
T57010 |
arg1Of |
elicit,"," |
| R689 |
T686 |
T684 |
arg2Of |
cluster,of |
| R68909 |
T18648 |
T40659 |
arg1Of |
interactions,glycan–glycan |
| R68911 |
T18913 |
T82055 |
arg2Of |
HIV-1,as |
| R68916 |
T66804 |
T90504 |
arg1Of |
surface,serve |
| R690 |
T686 |
T685 |
arg1Of |
cluster,a |
| R69033 |
T66049 |
T41086 |
arg1Of |
shield,an |
| R69064 |
T66354 |
T51052 |
arg2Of |
shielding,observed |
| R69077 |
T68204 |
T55529 |
arg1Of |
measured,in |
| R69083 |
T93400 |
T11696 |
arg1Of |
N-linked,Quantitative |
| R691 |
T686 |
T687 |
arg1Of |
cluster,of |
| R69107 |
T82951 |
T16903 |
arg1Of |
hallmark,of |
| R69140 |
T72195 |
T31422 |
arg2Of |
recognition,in |
| R692 |
T689 |
T687 |
arg2Of |
glycans,of |
| R69204 |
T8708 |
T54589 |
arg2Of |
importance,underscores |
| R69282 |
T4404 |
T32963 |
arg2Of |
and,of |
| R693 |
T689 |
T688 |
arg1Of |
glycans,oligomannose-type |
| R69300 |
T23381 |
T45120 |
arg2Of |
0.10,of |
| R69352 |
T60790 |
T18570 |
arg1Of |
domains,receptor-binding |
| R69367 |
T28749 |
T33039 |
arg1Of |
structures,of |
| R69392 |
T57392 |
T49504 |
arg1Of |
information,Additional |
| R694 |
T680 |
T690 |
arg1Of |
contribute,at |
| R69414 |
T56273 |
T66412 |
arg1Of |
map,with |
| R69440 |
T73114 |
T8410 |
arg1Of |
compare,in |
| R69444 |
T8512 |
T57382 |
arg1Of |
coronaviruses,several |
| R69466 |
T73114 |
T80633 |
arg1Of |
compare,difficult |
| R6949 |
T82481 |
T80845 |
arg2Of |
subunit,on |
| R69492 |
T32211 |
T29228 |
arg1Of |
elicit,on |
| R695 |
T692 |
T690 |
arg2Of |
regions,at |
| R69540 |
T96551 |
T87992 |
arg2Of |
MERS,and |
| R69562 |
T21025 |
T24463 |
arg1Of |
abundances,of |
| R696 |
T692 |
T691 |
arg1Of |
regions,specific |
| R69613 |
T2320 |
T64649 |
arg2Of |
addition,In |
| R69625 |
T68609 |
T42572 |
arg2Of |
structures,onto |
| R69629 |
T13786 |
T34488 |
arg2Of |
Fig. 3a,( |
| R6966 |
T58919 |
T51281 |
arg2Of |
and,as |
| R697 |
T692 |
T693 |
arg1Of |
regions,of |
| R69725 |
T35287 |
T82138 |
arg1Of |
virus,immunodeficiency |
| R69771 |
T21845 |
T37792 |
arg2Of |
"HIV-120,39",of |
| R69778 |
T54786 |
T20256 |
arg1Of |
"research22,60",influenza |
| R698 |
T696 |
T693 |
arg2Of |
density,of |
| R69846 |
T56245 |
T18704 |
arg1Of |
antibodies,single-domain |
| R6985 |
T34602 |
T68570 |
arg1Of |
structuring,higher-order |
| R69863 |
T23766 |
T88529 |
arg2Of |
reach,does |
| R69877 |
T54786 |
T66965 |
arg2Of |
"research22,60",during |
| R699 |
T696 |
T694 |
arg1Of |
density,high |
| R69922 |
T80639 |
T40837 |
arg1Of |
diversity,elevated |
| R69926 |
T46208 |
T14534 |
arg2Of |
spikes,of |
| R69930 |
T82137 |
T96908 |
arg2Of |
compositions,based |
| R6998 |
T69625 |
T60843 |
arg1Of |
study,this |
| R69986 |
T60437 |
T64573 |
arg1Of |
total,a |
| R69989 |
T8574 |
T21020 |
arg1Of |
highlighted,on |
| R700 |
T696 |
T695 |
arg1Of |
density,glycan |
| R70015 |
T55170 |
T30720 |
arg2Of |
inhibition,from |
| R70039 |
T11869 |
T97157 |
arg1Of |
sites,glycan |
| R70051 |
T63244 |
T77547 |
arg2Of |
mutations,of |
| R7009 |
T55170 |
T33234 |
arg1Of |
inhibition,of |
| R701 |
T680 |
T697 |
arg1Of |
contribute,on |
| R70110 |
T1963 |
T31422 |
arg1Of |
implicated,in |
| R70125 |
T91715 |
T58888 |
arg1Of |
glycoproteins,including |
| R702 |
T710 |
T697 |
arg2Of |
reveals,on |
| R7026 |
T75621 |
T84066 |
arg1Of |
interacting,with |
| R70293 |
T65616 |
T81755 |
arg1Of |
circles,the |
| R70296 |
T59603 |
T92287 |
arg2Of |
values,exhibited |
| R703 |
T700 |
T698 |
arg1Of |
Molecular,MERS-CoV |
| R70336 |
T80633 |
T32700 |
arg2Of |
difficult,is |
| R704 |
T700 |
T699 |
arg1Of |
Molecular,S. |
| R70463 |
T12931 |
T36239 |
arg2Of |
Env,for |
| R70477 |
T68609 |
T73775 |
arg1Of |
structures,of |
| R705 |
T702 |
T700 |
arg1Of |
analysis,Molecular |
| R706 |
T702 |
T701 |
arg1Of |
analysis,evolution |
| R70606 |
T93347 |
T2438 |
arg1Of |
of,as |
| R70659 |
T12419 |
T16685 |
arg1Of |
there,is |
| R70679 |
T80657 |
T20248 |
arg1Of |
protein,prototypic |
| R70687 |
T26306 |
T52822 |
arg1Of |
we,visualize |
| R707 |
T702 |
T703 |
arg1Of |
analysis,of |
| R70729 |
T72317 |
T2448 |
arg1Of |
S,( |
| R70746 |
T1830 |
T60855 |
arg1Of |
hinders,In |
| R70770 |
T53788 |
T99830 |
arg2Of |
functionality,hindered |
| R708 |
T708 |
T703 |
arg2Of |
genes,of |
| R70838 |
T52910 |
T48779 |
arg2Of |
and,indicated |
| R70842 |
T24412 |
T2009 |
arg1Of |
limit,to |
| R709 |
T708 |
T704 |
arg1Of |
genes,SARS |
| R7092 |
T92271 |
T59290 |
arg1Of |
rate66,and |
| R70932 |
T11314 |
T53947 |
arg2Of |
Env,exposed |
| R70962 |
T67622 |
T58043 |
arg1Of |
values,dN/dS |
| R70972 |
T51290 |
T93380 |
arg1Of |
are,and |
| R710 |
T704 |
T705 |
arg1Of |
SARS,and |
| R71016 |
T66750 |
T8001 |
arg1Of |
compared,"," |
| R71053 |
T61369 |
T85886 |
arg1Of |
ratio,of |
| R71079 |
T89551 |
T98213 |
arg2Of |
offer,may |
| R711 |
T706 |
T705 |
arg2Of |
MERS,and |
| R71132 |
T60774 |
T58850 |
arg2Of |
sites,of |
| R71165 |
T1508 |
T66208 |
arg1Of |
boundaries,between |
| R712 |
T708 |
T706 |
arg1Of |
genes,MERS |
| R71202 |
T60933 |
T74928 |
arg1Of |
illustrated,on |
| R7121 |
T62404 |
T50573 |
arg2Of |
100,and |
| R71233 |
T28749 |
T31179 |
arg1Of |
structures,and |
| R71256 |
T83312 |
T48004 |
arg2Of |
construct,in |
| R71285 |
T66915 |
T31759 |
arg2Of |
and,at |
| R713 |
T708 |
T707 |
arg1Of |
genes,S |
| R71341 |
T14194 |
T78202 |
arg1Of |
glycosylation,the |
| R71348 |
T1670 |
T57479 |
arg1Of |
trimming,of |
| R71368 |
T52825 |
T10378 |
arg2Of |
glycans,recognise |
| R71369 |
T74525 |
T25050 |
arg1Of |
but,"," |
| R714 |
T710 |
T709 |
arg1Of |
reveals,also |
| R71428 |
T85689 |
T12542 |
arg1Of |
proportion,a |
| R71448 |
T88912 |
T15821 |
arg1Of |
compared,in |
| R71487 |
T83032 |
T99058 |
arg1Of |
is,As |
| R715 |
T702 |
T710 |
arg1Of |
analysis,reveals |
| R71509 |
T72051 |
T75452 |
arg1Of |
populations,( |
| R71520 |
T35915 |
T26156 |
arg1Of |
structure,prefusion |
| R71539 |
T54609 |
T31759 |
arg1Of |
glycans,at |
| R71549 |
T26594 |
T1758 |
arg2Of |
had,as |
| R71577 |
T82290 |
T73267 |
arg2Of |
and,for |
| R71588 |
T79420 |
T49752 |
arg3Of |
),( |
| R716 |
T713 |
T710 |
arg2Of |
incidence,reveals |
| R71622 |
T82870 |
T67844 |
arg2Of |
protein,of |
| R71664 |
T85671 |
T14723 |
arg1Of |
illustrated,on |
| R71690 |
T86793 |
T11216 |
arg2Of |
epitopes,reduced |
| R717 |
T713 |
T711 |
arg1Of |
incidence,a |
| R71719 |
T94035 |
T25861 |
arg1Of |
and,respectively |
| R71746 |
T85021 |
T19591 |
arg1Of |
outbreaks,SARS |
| R718 |
T713 |
T712 |
arg1Of |
incidence,higher |
| R71846 |
T19557 |
T1830 |
arg2Of |
differ,hinders |
| R719 |
T713 |
T714 |
arg1Of |
incidence,of |
| R71914 |
T92910 |
T85890 |
arg1Of |
Residues,are |
| R71969 |
T42372 |
T72419 |
arg1Of |
S,MERS |
| R71972 |
T75781 |
T1970 |
arg2Of |
up,in |
| R720 |
T716 |
T714 |
arg2Of |
diversity,of |
| R72021 |
T17681 |
T73974 |
arg1Of |
candidates,vaccine |
| R721 |
T716 |
T715 |
arg1Of |
diversity,amino-acid |
| R7210 |
T12203 |
T85444 |
arg1Of |
spike,the |
| R72145 |
T60681 |
T14534 |
arg1Of |
diversification,of |
| R72163 |
T25542 |
T85581 |
arg1Of |
coverage,over |
| R722 |
T710 |
T717 |
arg1Of |
reveals,on |
| R72203 |
T20594 |
T7753 |
arg1Of |
residues,would |
| R72204 |
T7879 |
T44958 |
arg1Of |
structure,ensemble-average |
| R72278 |
T60433 |
T34895 |
arg1Of |
calculated,and |
| R72281 |
T67487 |
T69929 |
arg2Of |
and,whereas |
| R723 |
T720 |
T717 |
arg2Of |
surfaces,on |
| R72305 |
T45067 |
T82922 |
arg1Of |
glycans,on |
| R72328 |
T71179 |
T58601 |
arg3Of |
),( |
| R72329 |
T39966 |
T95730 |
arg3Of |
),( |
| R72365 |
T50573 |
T63910 |
arg2Of |
and,( |
| R724 |
T720 |
T718 |
arg1Of |
surfaces,the |
| R7241 |
T2450 |
T74217 |
arg1Of |
Env,and |
| R72417 |
T75525 |
T55713 |
arg2Of |
“shield”,of |
| R72438 |
T26477 |
T2107 |
arg1Of |
Left,to |
| R72441 |
T95298 |
T19490 |
arg1Of |
copies,of |
| R72485 |
T18666 |
T45711 |
arg1Of |
spectrometry,( |
| R72489 |
T18714 |
T46337 |
arg1Of |
shield,the |
| R725 |
T720 |
T719 |
arg2Of |
surfaces,exposed |
| R72593 |
T58857 |
T6148 |
arg1Of |
we,using |
| R726 |
T720 |
T721 |
arg1Of |
surfaces,of |
| R72605 |
T42677 |
T17537 |
arg1Of |
distribution,the |
| R72618 |
T1822 |
T46731 |
modOf |
is,Given |
| R727 |
T724 |
T721 |
arg2Of |
proteins,of |
| R72732 |
T23968 |
T83864 |
arg2Of |
exhibits,whereas |
| R7274 |
T99824 |
T87308 |
arg1Of |
density,all-encompassing |
| R72746 |
T90081 |
T8587 |
arg2Of |
exhibit,did |
| R72750 |
T33026 |
T62295 |
arg2Of |
glycans,of |
| R72760 |
T32211 |
T2480 |
arg1Of |
elicit,following |
| R72771 |
T38606 |
T56105 |
arg2Of |
GPC,derived |
| R728 |
T724 |
T722 |
arg1Of |
proteins,the |
| R72861 |
T55109 |
T1585 |
arg1Of |
solvent-accessible,"," |
| R729 |
T724 |
T723 |
arg1Of |
proteins,S |
| R72909 |
T45911 |
T72556 |
arg2Of |
S,of |
| R72931 |
T19555 |
T93956 |
arg1Of |
importance,have |
| R72941 |
T54943 |
T70467 |
arg1Of |
coronavirus,novel |
| R72983 |
T95089 |
T28342 |
arg2Of |
volume,and |
| R72986 |
T68523 |
T71413 |
arg2Of |
and,of |
| R72995 |
T20968 |
T70083 |
arg2Of |
and,of |
| R730 |
T720 |
T725 |
arg1Of |
surfaces,that |
| R7301 |
T72369 |
T63573 |
arg1Of |
substitutions,nucleotide |
| R7304 |
T14141 |
T67059 |
arg1Of |
presence,The |
| R73049 |
T75995 |
T33346 |
arg1Of |
observed,for |
| R73081 |
T64999 |
T53746 |
arg2Of |
23,with |
| R731 |
T720 |
T726 |
arg1Of |
surfaces,are |
| R73107 |
T62928 |
T57941 |
arg1Of |
glycans,the |
| R73123 |
T27860 |
T14782 |
arg1Of |
events,from |
| R732 |
T728 |
T726 |
arg2Of |
occluded,are |
| R73216 |
T81512 |
T55641 |
arg1Of |
18,of |
| R73217 |
T13277 |
T54555 |
arg2Of |
all,at |
| R73294 |
T65176 |
T93347 |
arg1Of |
n = 566,of |
| R73297 |
T75554 |
T16194 |
arg1Of |
spikes,which |
| R733 |
T728 |
T727 |
arg1Of |
occluded,not |
| R7333 |
T67409 |
T58794 |
arg1Of |
released,F |
| R7338 |
T54866 |
T84066 |
arg2Of |
glycans,with |
| R734 |
T731 |
T728 |
arg1Of |
glycans,occluded |
| R73400 |
T34602 |
T35212 |
arg1Of |
structuring,in |
| R7341 |
T2440 |
T57258 |
arg2Of |
glycoproteins,of |
| R73473 |
T30435 |
T66630 |
arg2Of |
targeted,be |
| R73479 |
T3337 |
T25513 |
arg1Of |
shield51,the |
| R735 |
T720 |
T728 |
arg2Of |
surfaces,occluded |
| R73554 |
T98112 |
T45765 |
arg1Of |
domain,the |
| R73569 |
T67026 |
T98351 |
arg1Of |
domains,in |
| R736 |
T731 |
T729 |
arg2Of |
glycans,by |
| R73678 |
T90081 |
T74525 |
arg1Of |
exhibit,but |
| R737 |
T731 |
T730 |
arg1Of |
glycans,N-linked |
| R73701 |
T80500 |
T12634 |
arg2Of |
residues,buried |
| R73752 |
T83020 |
T70902 |
arg1Of |
presence,plays |
| R73775 |
T27072 |
T4572 |
arg1Of |
Env49,HIV-1 |
| R738 |
T746 |
T732 |
arg1Of |
and,In |
| R73807 |
T77577 |
T83032 |
arg1Of |
observed,is |
| R7381 |
T39941 |
T80371 |
arg1Of |
genes,SARS-CoV-2 |
| R73831 |
T37762 |
T91373 |
arg1Of |
additions,and |
| R73887 |
T51449 |
T56776 |
arg1Of |
proteins,I |
| R739 |
T733 |
T732 |
arg2Of |
addition,In |
| R73901 |
T32624 |
T63332 |
arg1Of |
diversity,sequence |
| R73995 |
T15044 |
T73857 |
arg2Of |
and,convolved |
| R740 |
T746 |
T734 |
arg1Of |
and,"," |
| R74094 |
T74143 |
T2361 |
arg1Of |
density,the |
| R741 |
T735 |
T736 |
arg1Of |
we,compare |
| R74108 |
T65172 |
T14314 |
arg1Of |
domain,receptor-binding |
| R74158 |
T79747 |
T37495 |
arg1Of |
key,the |
| R74168 |
T56514 |
T9118 |
arg1Of |
population,oligomannose-type |
| R742 |
T738 |
T736 |
arg2Of |
structures,compare |
| R74212 |
T32200 |
T30461 |
arg1Of |
antibodies,neutralizing |
| R74218 |
T58510 |
T22530 |
arg2Of |
level,at |
| R74249 |
T73688 |
T68517 |
arg1Of |
effects,shielding |
| R74251 |
T87992 |
T29922 |
arg2Of |
and,for |
| R743 |
T738 |
T737 |
arg1Of |
structures,the |
| R74388 |
T55814 |
T51235 |
arg1Of |
and,upon |
| R7439 |
T13006 |
T89961 |
arg1Of |
sites,glycosylation |
| R74391 |
T20048 |
T80278 |
arg2Of |
response,in |
| R74395 |
T37597 |
T10901 |
arg1Of |
data,of |
| R744 |
T738 |
T739 |
arg1Of |
structures,of |
| R74402 |
T93322 |
T68214 |
arg1Of |
context,structural |
| R74494 |
T43073 |
T22579 |
arg2Of |
overlaid,with |
| R74499 |
T83825 |
T2785 |
arg2Of |
indicate,while |
| R745 |
T743 |
T739 |
arg2Of |
coats,of |
| R74540 |
T96423 |
T90159 |
arg2Of |
spikes,of |
| R74579 |
T25133 |
T64136 |
arg3Of |
pink,dashed |
| R746 |
T743 |
T740 |
arg1Of |
coats,the |
| R74679 |
T94405 |
T76643 |
arg1Of |
model,of |
| R747 |
T743 |
T741 |
arg1Of |
coats,respective |
| R74774 |
T14190 |
T8187 |
arg1Of |
analysis,3D |
| R748 |
T743 |
T742 |
arg1Of |
coats,glycan |
| R74870 |
T1468 |
T1478 |
arg1Of |
highlight,and |
| R749 |
T743 |
T744 |
arg1Of |
coats,of |
| R74950 |
T29035 |
T95898 |
arg1Of |
Comparison,b |
| R74985 |
T33026 |
T78639 |
arg1Of |
glycans,PNGase |
| R74990 |
T61088 |
T96660 |
arg1Of |
targeted,and |
| R750 |
T745 |
T744 |
arg2Of |
SARS,of |
| R75062 |
T73464 |
T90139 |
arg2Of |
library,generated |
| R751 |
T736 |
T746 |
arg1Of |
compare,and |
| R7514 |
T1932 |
T96910 |
arg1Of |
glycoproteins,viral |
| R75191 |
T90504 |
T9316 |
arg2Of |
serve,can |
| R752 |
T766 |
T746 |
arg2Of |
exhibited,and |
| R75268 |
T55216 |
T15548 |
arg1Of |
We,would |
| R753 |
T749 |
T747 |
arg1Of |
proteins,HIV-1 |
| R754 |
T749 |
T748 |
arg1Of |
proteins,envelope |
| R75418 |
T11621 |
T31174 |
arg1Of |
offer,against |
| R75492 |
T6464 |
T51710 |
arg1Of |
",","," |
| R755 |
T749 |
T750 |
arg1Of |
proteins,using |
| R75510 |
T51449 |
T13008 |
arg2Of |
proteins,of |
| R75547 |
T81925 |
T11525 |
arg1Of |
proteins,S |
| R75548 |
T66936 |
T36773 |
arg1Of |
number,of |
| R756 |
T756 |
T750 |
arg2Of |
and,using |
| R75613 |
T76651 |
T63553 |
arg1Of |
assortment,of |
| R75632 |
T88390 |
T93961 |
arg2Of |
glycans,colored |
| R7569 |
T96185 |
T74217 |
arg2Of |
"GPC24,31,34,36,45,46",and |
| R75695 |
T79747 |
T30404 |
arg2Of |
key,by |
| R75698 |
T75781 |
T91066 |
arg1Of |
up,both |
| R757 |
T752 |
T751 |
arg1Of |
microscopy,cryo-electron |
| R75703 |
T66013 |
T67487 |
arg1Of |
appear,and |
| R75722 |
T59672 |
T90413 |
arg2Of |
considered,be |
| R75726 |
T48991 |
T34520 |
arg2Of |
Fig. 4a,( |
| R75729 |
T71146 |
T85890 |
arg2Of |
colored,are |
| R7575 |
T64331 |
T56294 |
arg1Of |
ratios,mean |
| R7577 |
T19207 |
T62312 |
arg3Of |
),( |
| R75794 |
T94055 |
T84292 |
arg2Of |
comparisons,of |
| R75798 |
T85021 |
T62735 |
arg2Of |
outbreaks,and |
| R758 |
T752 |
T753 |
arg1Of |
microscopy,( |
| R75856 |
T42577 |
T48803 |
arg1Of |
modulation,of |
| R75872 |
T59830 |
T17878 |
arg1Of |
elevated,significantly |
| R759 |
T754 |
T753 |
arg2Of |
cryo-EM,( |
| R75905 |
T35287 |
T35124 |
arg1Of |
virus,MERS |
| R75933 |
T77577 |
T56317 |
arg1Of |
observed,it |
| R75968 |
T5466 |
T11453 |
arg2Of |
glycans,with |
| R75973 |
T96165 |
T84433 |
arg2Of |
residues,of |
| R760 |
T755 |
T753 |
arg3Of |
),( |
| R76012 |
T27050 |
T31852 |
arg1Of |
microscopy,single-particle |
| R761 |
T752 |
T756 |
arg1Of |
microscopy,and |
| R76131 |
T87240 |
T22579 |
arg1Of |
visualised,with |
| R76144 |
T61476 |
T62752 |
arg2Of |
residues,of |
| R76150 |
T77577 |
T80845 |
arg1Of |
observed,on |
| R76166 |
T18714 |
T52476 |
arg1Of |
shield,evolving |
| R76178 |
T78169 |
T64492 |
arg2Of |
N166A,"," |
| R76184 |
T52424 |
T60202 |
arg1Of |
Comparison,Fig. |
| R76187 |
T15627 |
T44925 |
arg1Of |
nanobodies,camel |
| R762 |
T758 |
T756 |
arg2Of |
modelling,and |
| R76229 |
T67457 |
T72214 |
arg3Of |
),( |
| R76231 |
T63979 |
T83914 |
arg1Of |
level,a |
| R76273 |
T82137 |
T30425 |
arg1Of |
compositions,are |
| R76283 |
T43156 |
T41089 |
arg2Of |
intervals,to |
| R763 |
T758 |
T757 |
arg1Of |
modelling,computational |
| R7635 |
T90188 |
T68941 |
arg1Of |
map,Low-pass |
| R76365 |
T35124 |
T37894 |
arg1Of |
MERS,glycosylated |
| R76378 |
T58864 |
T59844 |
arg2Of |
diversity,to |
| R764 |
T758 |
T759 |
arg1Of |
modelling,"," |
| R76401 |
T15627 |
T31174 |
arg2Of |
nanobodies,against |
| R76412 |
T40801 |
T85225 |
arg1Of |
are,Although |
| R76425 |
T10224 |
T41739 |
arg1Of |
MERS,trimeric |
| R76452 |
T81231 |
T72942 |
arg2Of |
considered,can |
| R765 |
T758 |
T760 |
arg1Of |
modelling,which |
| R76558 |
T48004 |
T52255 |
arg1Of |
in,as |
| R76563 |
T30576 |
T94991 |
arg1Of |
S,SARS |
| R7658 |
T58744 |
T10901 |
arg2Of |
quality,of |
| R76589 |
T39985 |
T77299 |
arg2Of |
incorporated,be |
| R766 |
T758 |
T761 |
arg1Of |
modelling,delineate |
| R76630 |
T13582 |
T53208 |
arg2Of |
and,on |
| R76646 |
T3759 |
T24472 |
arg2Of |
S,of |
| R76670 |
T94857 |
T97958 |
arg1Of |
Mapping,c |
| R76672 |
T4098 |
T79086 |
arg2Of |
Fig. 6,( |
| R767 |
T765 |
T761 |
arg2Of |
shield,delineate |
| R76705 |
T83410 |
T85418 |
arg2Of |
Fig. 3a,( |
| R768 |
T765 |
T762 |
arg1Of |
shield,a |
| R76809 |
T38543 |
T91973 |
arg1Of |
glycosylated,but |
| R76821 |
T49153 |
T52169 |
arg2Of |
density,in |
| R769 |
T765 |
T763 |
arg1Of |
shield,sparse |
| R76910 |
T74921 |
T5294 |
arg1Of |
panel,: |
| R76941 |
T7541 |
T94235 |
arg2Of |
S,on |
| R76944 |
T10989 |
T94198 |
arg1Of |
"response21,31",immune |
| R770 |
T765 |
T764 |
arg1Of |
shield,glycan |
| R77034 |
T39672 |
T1585 |
arg2Of |
amino-acid,"," |
| R77082 |
T65417 |
T71938 |
arg1Of |
differ,significantly |
| R771 |
T749 |
T766 |
arg1Of |
proteins,exhibited |
| R77147 |
T65942 |
T19490 |
arg2Of |
Fabs51,of |
| R772 |
T769 |
T766 |
arg2Of |
S,exhibited |
| R77296 |
T58857 |
T3483 |
arg1Of |
we,performed |
| R773 |
T766 |
T767 |
arg1Of |
exhibited,on |
| R7735 |
T28741 |
T30776 |
arg1Of |
mapping,S |
| R774 |
T768 |
T767 |
arg2Of |
SARS,on |
| R77404 |
T3174 |
T27555 |
arg1Of |
Env,is |
| R77410 |
T34000 |
T54890 |
arg1Of |
receptor-binding,and |
| R77417 |
T35201 |
T72056 |
arg1Of |
reflected,in |
| R775 |
T766 |
T770 |
arg1Of |
exhibited,compared |
| R77574 |
T65417 |
T56277 |
arg1Of |
differ,depending |
| R77591 |
T15804 |
T55323 |
arg1Of |
elicit,to |
| R776 |
T771 |
T770 |
arg2Of |
with,compared |
| R77630 |
T95497 |
T33229 |
arg2Of |
in,being |
| R777 |
T774 |
T771 |
arg2Of |
glycoproteins,with |
| R77726 |
T53788 |
T63119 |
arg1Of |
functionality,that |
| R77739 |
T30887 |
T45174 |
arg1Of |
are,Furthermore |
| R77752 |
T13646 |
T61859 |
arg2Of |
glycoprotein,of |
| R77760 |
T21302 |
T92374 |
arg1Of |
shields,HIV-1 |
| R77763 |
T54724 |
T72837 |
arg2Of |
mapped,were |
| R77783 |
T80500 |
T77635 |
arg1Of |
residues,on |
| R77790 |
T15044 |
T7534 |
arg1Of |
and,limits |
| R778 |
T774 |
T772 |
arg1Of |
glycoproteins,other |
| R77813 |
T47879 |
T44006 |
arg2Of |
down,and |
| R77821 |
T44762 |
T45752 |
arg2Of |
labelled,were |
| R77886 |
T14190 |
T89162 |
arg2Of |
analysis,as |
| R77888 |
T95787 |
T67617 |
arg2Of |
number,by |
| R779 |
T774 |
T773 |
arg1Of |
glycoproteins,viral |
| R77907 |
T89313 |
T10630 |
arg1Of |
much,as |
| R77919 |
T72666 |
T68472 |
arg2Of |
approach,using |
| R77925 |
T13523 |
T88928 |
arg2Of |
glycans,of |
| R77938 |
T2354 |
T99079 |
arg1Of |
subunit,the |
| R780 |
T777 |
T776 |
arg1Of |
undertook,therefore |
| R78036 |
T80993 |
T47375 |
modOf |
mutagenesis,to |
| R78049 |
T6629 |
T90729 |
arg1Of |
compositions,glycan |
| R78066 |
T15412 |
T19099 |
arg1Of |
domains,protrude |
| R78078 |
T66339 |
T85203 |
arg1Of |
incapable,of |
| R78096 |
T18180 |
T41564 |
arg2Of |
shielding,of |
| R781 |
T775 |
T777 |
arg1Of |
We,undertook |
| R78120 |
T4213 |
T33263 |
arg2Of |
evidence,and |
| R78128 |
T64543 |
T21071 |
arg2Of |
zoonosis,to |
| R78169 |
T73192 |
T19328 |
arg2Of |
result,suggest |
| R78175 |
T50969 |
T34676 |
arg2Of |
limit,be |
| R782 |
T780 |
T777 |
arg2Of |
analysis,undertook |
| R78201 |
T5616 |
T50579 |
arg2Of |
HAs,including |
| R78238 |
T67674 |
T40801 |
arg2Of |
comparable,are |
| R78256 |
T34663 |
T42643 |
arg2Of |
observed,are |
| R783 |
T780 |
T778 |
arg1Of |
analysis,a |
| R78301 |
T2354 |
T3040 |
arg1Of |
subunit,S1 |
| R78333 |
T23058 |
T22092 |
arg2Of |
Fig. 7,( |
| R784 |
T780 |
T779 |
arg1Of |
analysis,comparative |
| R78404 |
T55295 |
T74940 |
arg1Of |
proteins,"," |
| R78452 |
T49843 |
T77547 |
arg1Of |
hotspots,of |
| R78471 |
T41188 |
T15094 |
arg3Of |
:,( |
| R785 |
T780 |
T781 |
arg1Of |
analysis,of |
| R78518 |
T55061 |
T79381 |
arg1Of |
cells,kidney |
| R78533 |
T92849 |
T42940 |
arg1Of |
residues,had |
| R78557 |
T98636 |
T79458 |
arg1Of |
dN/dS,thus |
| R78580 |
T85214 |
T67973 |
arg1Of |
and,11 |
| R786 |
T801 |
T781 |
arg2Of |
and,of |
| R78619 |
T64712 |
T33742 |
arg1Of |
bars,The |
| R78626 |
T6494 |
T37727 |
arg1Of |
sites,other |
| R78632 |
T90485 |
T23317 |
arg1Of |
exemplifies,firmly |
| R787 |
T784 |
T782 |
arg1Of |
shields,viral |
| R78728 |
T80844 |
T55852 |
arg1Of |
networks,wide-ranging |
| R78741 |
T72666 |
T29179 |
arg1Of |
approach,structural |
| R788 |
T784 |
T783 |
arg1Of |
shields,glycan |
| R78811 |
T11708 |
T15706 |
arg1Of |
5X58,ID |
| R78857 |
T76130 |
T2696 |
arg2Of |
site,occluded |
| R78874 |
T10175 |
T52708 |
arg2Of |
spectrometry,from |
| R789 |
T784 |
T785 |
arg1Of |
shields,from |
| R78903 |
T15412 |
T29918 |
arg1Of |
domains,receptor-binding |
| R7891 |
T4098 |
T21819 |
arg1Of |
Fig. 6,SI |
| R78916 |
T28935 |
T59995 |
arg2Of |
behaviour,in |
| R78991 |
T84232 |
T10378 |
arg1Of |
"lectins47,48",recognise |
| R790 |
T790 |
T785 |
arg2Of |
proteins,from |
| R79004 |
T70221 |
T82660 |
arg1Of |
proteins,( |
| R79007 |
T89747 |
T9896 |
arg1Of |
accretion,on |
| R79050 |
T46103 |
T44946 |
arg2Of |
MERS,and |
| R791 |
T790 |
T786 |
arg2Of |
proteins,characterized |
| R79103 |
T93372 |
T10897 |
arg1Of |
accommodate,to |
| R7917 |
T84232 |
T90164 |
arg2Of |
"lectins47,48",by |
| R79187 |
T46270 |
T95681 |
arg1Of |
models,glycosylated |
| R792 |
T790 |
T787 |
arg1Of |
proteins,class |
| R79212 |
T17681 |
T12004 |
arg1Of |
candidates,MERS-CoV |
| R79222 |
T92120 |
T41703 |
arg1Of |
analysed,then |
| R7923 |
T89591 |
T30619 |
arg1Of |
shown,also |
| R79248 |
T76353 |
T26368 |
arg1Of |
evolved,since |
| R79260 |
T67674 |
T5187 |
arg1Of |
comparable,directly |
| R79271 |
T74716 |
T40337 |
arg1Of |
is,surprising |
| R79279 |
T12679 |
T68523 |
arg2Of |
CoVs,and |
| R793 |
T790 |
T788 |
arg1Of |
proteins,I |
| R79333 |
T27628 |
T33888 |
arg3Of |
),( |
| R79355 |
T56514 |
T32151 |
arg1Of |
population,arises |
| R7938 |
T26472 |
T57713 |
arg1Of |
subunit,the |
| R79398 |
T36486 |
T71292 |
arg1Of |
all,of |
| R794 |
T790 |
T789 |
arg1Of |
proteins,fusion |
| R79407 |
T8708 |
T99300 |
arg1Of |
importance,of |
| R79421 |
T73464 |
T48766 |
arg1Of |
library,the |
| R79491 |
T70981 |
T34848 |
arg1Of |
due,to |
| R795 |
T792 |
T791 |
arg1Of |
highlight,to |
| R79506 |
T10901 |
T46398 |
arg2Of |
of,were |
| R79509 |
T84653 |
T38543 |
arg2Of |
proteins,glycosylated |
| R79558 |
T10907 |
T19441 |
arg1Of |
Hybrid,F |
| R796 |
T784 |
T791 |
modOf |
shields,to |
| R7964 |
T89667 |
T97762 |
arg2Of |
characterized,was |
| R79677 |
T80082 |
T33781 |
arg1Of |
glycopeptides,which |
| R797 |
T793 |
T792 |
arg2Of |
how,highlight |
| R79721 |
T82634 |
T17084 |
arg2Of |
and,on |
| R7973 |
T76361 |
T13147 |
arg1Of |
proteins,S |
| R798 |
T796 |
T793 |
arg1Of |
influences,how |
| R79815 |
T60225 |
T86262 |
arg1Of |
interactions,host-virus |
| R79877 |
T39891 |
T4854 |
arg1Of |
core,the |
| R799 |
T795 |
T794 |
arg1Of |
density,glycosylation |
| R79922 |
T94055 |
T34101 |
arg1Of |
comparisons,pairwise |
| R79979 |
T86129 |
T85155 |
arg1Of |
viruses,able |
| R79993 |
T53746 |
T81728 |
arg2Of |
with,compared |
| R800 |
T795 |
T796 |
arg1Of |
density,influences |
| R80018 |
T81349 |
T82468 |
arg1Of |
glycosylation,viral |
| R80062 |
T78881 |
T91114 |
arg1Of |
4O5N,"," |
| R80086 |
T5616 |
T5660 |
arg1Of |
HAs,"," |
| R80093 |
T14034 |
T48546 |
arg1Of |
processing,i.e. |
| R801 |
T799 |
T796 |
arg2Of |
abundance,influences |
| R802 |
T799 |
T797 |
arg1Of |
abundance,oligomannose-type |
| R80207 |
T9415 |
T12417 |
arg1Of |
variability,the |
| R80238 |
T56321 |
T97416 |
arg2Of |
cryo-EM,( |
| R803 |
T799 |
T798 |
arg1Of |
abundance,glycan |
| R8034 |
T91138 |
T68502 |
arg1Of |
residues,mannose |
| R80363 |
T16712 |
T95489 |
arg1Of |
domains,the |
| R80364 |
T93681 |
T55814 |
arg2Of |
HAs,and |
| R80378 |
T26744 |
T42360 |
arg1Of |
viruses,other |
| R8039 |
T47272 |
T70958 |
arg2Of |
fusion,including |
| R804 |
T801 |
T800 |
arg1Of |
and,"," |
| R80415 |
T33026 |
T15765 |
arg1Of |
glycans,N-linked |
| R80462 |
T57392 |
T38584 |
arg1Of |
information,regarding |
| R80497 |
T18714 |
T90485 |
arg1Of |
shield,exemplifies |
| R805 |
T784 |
T801 |
arg1Of |
shields,and |
| R80505 |
T68442 |
T66412 |
arg2Of |
domains,with |
| R80519 |
T79677 |
T47791 |
arg1Of |
maps,variability |
| R80551 |
T11708 |
T73014 |
arg2Of |
5X58,( |
| R80559 |
T40134 |
T10289 |
arg1Of |
degrees,varying |
| R806 |
T803 |
T801 |
arg2Of |
relationship,and |
| R80635 |
T72666 |
T21412 |
arg1Of |
approach,plotted |
| R80658 |
T18790 |
T44481 |
arg2Of |
glycans,by |
| R807 |
T803 |
T802 |
arg1Of |
relationship,the |
| R80710 |
T13436 |
T55600 |
arg1Of |
but,Indeed |
| R80715 |
T19555 |
T95262 |
arg1Of |
importance,in |
| R80721 |
T56273 |
T86558 |
arg1Of |
map,of |
| R808 |
T803 |
T804 |
arg1Of |
relationship,between |
| R80868 |
T68699 |
T71503 |
arg2Of |
presented,are |
| R80879 |
T60493 |
T54925 |
arg1Of |
using,analyses |
| R809 |
T808 |
T804 |
arg2Of |
and,between |
| R80940 |
T37894 |
T45576 |
arg1Of |
glycosylated,fully |
| R80943 |
T54715 |
T56258 |
arg1Of |
glycans,only |
| R80985 |
T30346 |
T31809 |
arg1Of |
sites,these |
| R80995 |
T28404 |
T42537 |
arg1Of |
S.,SARS |
| R810 |
T807 |
T805 |
arg1Of |
shields,effective |
| R81049 |
T32200 |
T51281 |
arg1Of |
antibodies,as |
| R81060 |
T46492 |
T25102 |
arg2Of |
and,occluded |
| R81081 |
T65172 |
T92413 |
arg2Of |
domain,of |
| R811 |
T807 |
T806 |
arg1Of |
shields,glycan |
| R81127 |
T55156 |
T13067 |
arg1Of |
vulnerabilities,permeating |
| R81139 |
T27945 |
T36773 |
arg2Of |
residues,of |
| R81143 |
T24662 |
T56739 |
arg2Of |
GPC,to |
| R81187 |
T16354 |
T90159 |
arg1Of |
models,of |
| R81192 |
T6148 |
T3483 |
arg3Of |
using,performed |
| R812 |
T807 |
T808 |
arg1Of |
shields,and |
| R81263 |
T60433 |
T75361 |
arg2Of |
calculated,was |
| R813 |
T811 |
T808 |
arg2Of |
ability,and |
| R81334 |
T38368 |
T7627 |
arg1Of |
We,suggest |
| R8136 |
T73292 |
T38605 |
arg1Of |
analysis,Site-specific |
| R81378 |
T39985 |
T69288 |
arg2Of |
incorporated,can |
| R814 |
T811 |
T809 |
arg1Of |
ability,viral |
| R815 |
T811 |
T810 |
arg1Of |
ability,evasion |
| R8157 |
T35201 |
T83864 |
arg1Of |
reflected,whereas |
| R81574 |
T28124 |
T70489 |
arg1Of |
",","," |
| R81587 |
T99824 |
T57545 |
arg1Of |
density,the |
| R816 |
T816 |
T812 |
arg1Of |
underscore,Together |
| R81612 |
T23755 |
T36496 |
arg1Of |
charts,The |
| R81614 |
T95787 |
T84433 |
arg1Of |
number,of |
| R81667 |
T63465 |
T63209 |
arg1Of |
virus,“evasion |
| R81691 |
T56477 |
T73121 |
arg1Of |
is,whereas |
| R817 |
T816 |
T813 |
arg1Of |
underscore,"," |
| R81741 |
T86087 |
T48007 |
arg2Of |
mutations,of |
| R818 |
T815 |
T814 |
arg1Of |
data,these |
| R81839 |
T88004 |
T43617 |
arg1Of |
mutants,glycan-KO |
| R81851 |
T74546 |
T11993 |
arg1Of |
investigated,also |
| R81871 |
T15004 |
T27520 |
arg2Of |
region,in |
| R81880 |
T31925 |
T4958 |
arg1Of |
",",respectively |
| R81896 |
T65172 |
T48963 |
arg1Of |
domain,the |
| R819 |
T815 |
T816 |
arg1Of |
data,underscore |
| R81910 |
T34685 |
T91376 |
arg1Of |
and,larger |
| R8195 |
T3893 |
T1991 |
arg2Of |
shown,"," |
| R81995 |
T36825 |
T5712 |
arg3Of |
),( |
| R820 |
T818 |
T816 |
arg2Of |
importance,underscore |
| R82082 |
T18688 |
T54076 |
arg1Of |
SARS,and |
| R82084 |
T28675 |
T51290 |
arg2Of |
sensitive,are |
| R82099 |
T67026 |
T21547 |
arg1Of |
domains,the |
| R821 |
T818 |
T817 |
arg1Of |
importance,the |
| R82101 |
T20315 |
T28124 |
arg1Of |
",","," |
| R82156 |
T26744 |
T82055 |
arg1Of |
viruses,as |
| R82172 |
T75679 |
T96992 |
arg1Of |
sequences,MERS |
| R822 |
T818 |
T819 |
arg1Of |
importance,of |
| R82201 |
T1830 |
T83757 |
arg1Of |
hinders,"," |
| R8222 |
T3483 |
T62380 |
arg1Of |
performed,"," |
| R82223 |
T60202 |
T35932 |
arg1Of |
Fig.,6 |
| R82225 |
T94995 |
T43286 |
arg2Of |
it,penetrate |
| R82299 |
T59290 |
T1830 |
arg1Of |
and,hinders |
| R823 |
T820 |
T819 |
arg2Of |
glycosylation,of |
| R82360 |
T43073 |
T91266 |
arg1Of |
overlaid,map |
| R824 |
T818 |
T821 |
arg1Of |
importance,in |
| R82405 |
T49535 |
T90485 |
arg2Of |
it,exemplifies |
| R82423 |
T72666 |
T54019 |
arg1Of |
approach,a |
| R82455 |
T72864 |
T60407 |
arg1Of |
S1,and |
| R82494 |
T88882 |
T33407 |
arg1Of |
subject,likely |
| R825 |
T824 |
T821 |
arg2Of |
evasion,in |
| R8253 |
T16085 |
T80700 |
arg1Of |
resolutions,the |
| R8259 |
T56838 |
T86817 |
arg2Of |
protease,"," |
| R826 |
T824 |
T822 |
arg1Of |
evasion,viral |
| R827 |
T824 |
T823 |
arg1Of |
evasion,immune |
| R82759 |
T12473 |
T49752 |
arg1Of |
reduced,( |
| R82764 |
T22349 |
T84588 |
arg2Of |
viruses,to |
| R82776 |
T96423 |
T16192 |
arg1Of |
spikes,using |
| R828 |
T825 |
T826 |
arg1Of |
Results,and |
| R82819 |
T43073 |
T51416 |
arg1Of |
overlaid,a |
| R82820 |
T99241 |
T52952 |
arg2Of |
with,compared |
| R82833 |
T78120 |
T15044 |
arg2Of |
2D-variability,and |
| R82865 |
T98975 |
T16688 |
arg2Of |
majority,for |
| R82869 |
T54925 |
T13544 |
arg1Of |
analyses,of |
| R829 |
T827 |
T826 |
arg2Of |
discussion,and |
| R8290 |
T10460 |
T78780 |
arg1Of |
and,MERS |
| R82991 |
T77800 |
T64664 |
arg1Of |
analysis,revealed |
| R830 |
T829 |
T828 |
arg1Of |
processing,Glycan |
| R8307 |
T80639 |
T14256 |
arg2Of |
diversity,with |
| R83070 |
T12246 |
T16571 |
arg1Of |
sites,glycosylation |
| R831 |
T829 |
T830 |
arg1Of |
processing,of |
| R83158 |
T31427 |
T76296 |
arg1Of |
proteins,were |
| R83184 |
T29760 |
T29294 |
arg2Of |
repeat,"," |
| R832 |
T833 |
T830 |
arg2Of |
and,of |
| R83267 |
T16354 |
T84875 |
arg3Of |
models,generated |
| R83297 |
T10009 |
T95182 |
arg2Of |
studied,"," |
| R833 |
T832 |
T831 |
arg1Of |
SARS,trimeric |
| R83314 |
T54715 |
T89329 |
arg2Of |
glycans,isolated |
| R8332 |
T30217 |
T24446 |
arg1Of |
modelling,of |
| R83333 |
T67674 |
T16791 |
arg1Of |
comparable,between |
| R83350 |
T38232 |
T41652 |
arg2Of |
traces,as |
| R83368 |
T82356 |
T87134 |
arg1Of |
diversity,in |
| R834 |
T832 |
T833 |
arg1Of |
SARS,and |
| R83407 |
T11968 |
T7451 |
arg2Of |
Interfaces,"," |
| R83415 |
T95298 |
T56194 |
arg2Of |
copies,with |
| R83418 |
T70221 |
T91777 |
arg1Of |
proteins,HKU1 |
| R83430 |
T16169 |
T7534 |
arg2Of |
interpretability,limits |
| R83497 |
T97319 |
T54253 |
arg1Of |
role,major |
| R835 |
T836 |
T833 |
arg2Of |
proteins,and |
| R83504 |
T32200 |
T53019 |
arg2Of |
antibodies,by |
| R83516 |
T77334 |
T3264 |
arg1Of |
We,investigated |
| R83519 |
T66745 |
T96535 |
arg2Of |
trimer,throughout |
| R83562 |
T14383 |
T56235 |
arg1Of |
Env,HIV-1 |
| R836 |
T836 |
T834 |
arg1Of |
proteins,MERS |
| R83664 |
T52822 |
T32196 |
arg3Of |
visualize,In |
| R83690 |
T1661 |
T98847 |
arg1Of |
glycans,these |
| R837 |
T836 |
T835 |
arg1Of |
proteins,spike |
| R8373 |
T14068 |
T36252 |
arg1Of |
exposed,and |
| R83742 |
T45372 |
T9612 |
arg1Of |
tempting,"," |
| R838 |
T838 |
T837 |
arg1Of |
generate,To |
| R83861 |
T99799 |
T3017 |
arg1Of |
glycoproteins,11 |
| R839 |
T849 |
T837 |
modOf |
used,To |
| R83994 |
T30415 |
T52236 |
arg1Of |
compare,with |
| R83995 |
T54061 |
T48581 |
arg1Of |
proteins,b |
| R840 |
T848 |
T838 |
arg1Of |
we,generate |
| R84025 |
T82430 |
T89162 |
arg1Of |
combination,as |
| R84039 |
T75213 |
T43420 |
arg1Of |
peptide,and |
| R8406 |
T35287 |
T35247 |
arg1Of |
virus,simian |
| R841 |
T841 |
T838 |
arg2Of |
mimic,generate |
| R84135 |
T68027 |
T88612 |
arg1Of |
level,a |
| R84142 |
T4934 |
T87263 |
arg2Of |
responses,by |
| R842 |
T841 |
T839 |
arg1Of |
mimic,a |
| R84232 |
T34718 |
T34663 |
arg3Of |
As,observed |
| R84233 |
T43199 |
T13552 |
arg1Of |
diversity,genetic |
| R8424 |
T15422 |
T85581 |
arg2Of |
surface,over |
| R8425 |
T47125 |
T63067 |
arg1Of |
results,were |
| R843 |
T841 |
T840 |
arg1Of |
mimic,soluble |
| R84300 |
T99472 |
T76117 |
arg2Of |
constraints,to |
| R84349 |
T5930 |
T8049 |
arg1Of |
infectivity,and |
| R84393 |
T93319 |
T26621 |
arg1Of |
domains,central |
| R844 |
T841 |
T842 |
arg1Of |
mimic,of |
| R84419 |
T47125 |
T36239 |
arg1Of |
results,for |
| R845 |
T846 |
T842 |
arg2Of |
proteins,of |
| R84573 |
T63130 |
T65568 |
arg1Of |
surface,protein |
| R84584 |
T44450 |
T90266 |
arg1Of |
coronaviruses,SARS |
| R846 |
T846 |
T843 |
arg1Of |
proteins,the |
| R84605 |
T66804 |
T66208 |
arg2Of |
surface,between |
| R84616 |
T64768 |
T68800 |
arg1Of |
represent,"," |
| R84660 |
T62826 |
T41174 |
arg1Of |
Fig. 2a,"," |
| R84665 |
T28528 |
T60922 |
arg1Of |
measure,for |
| R84672 |
T26990 |
T48789 |
arg2Of |
A,in |
| R84689 |
T71248 |
T26853 |
arg2Of |
expressed,were |
| R847 |
T846 |
T844 |
arg1Of |
proteins,viral |
| R84719 |
T53941 |
T55209 |
arg1Of |
SOSIP.664,BG505 |
| R84767 |
T4934 |
T84547 |
arg1Of |
responses,host |
| R84776 |
T38543 |
T78070 |
arg1Of |
glycosylated,to |
| R84782 |
T93319 |
T88882 |
arg1Of |
domains,subject |
| R84789 |
T37597 |
T46398 |
arg1Of |
data,were |
| R848 |
T846 |
T845 |
arg1Of |
proteins,S |
| R84867 |
T1436 |
T1435 |
arg1Of |
regions,accessible |
| R849 |
T849 |
T847 |
arg1Of |
used,"," |
| R84962 |
T79747 |
T86418 |
arg1Of |
key,defined |
| R84986 |
T91715 |
T8442 |
arg2Of |
glycoproteins,on |
| R850 |
T848 |
T849 |
arg1Of |
we,used |
| R8502 |
T61005 |
T70489 |
arg2Of |
Env,"," |
| R85023 |
T20998 |
T90752 |
arg1Of |
regions,oligomannose |
| R85024 |
T31963 |
T11453 |
arg1Of |
interact,with |
| R85033 |
T73114 |
T73791 |
arg1Of |
compare,to |
| R85039 |
T47078 |
T36523 |
arg1Of |
possesses,with |
| R85045 |
T79412 |
T18710 |
arg1Of |
is,"," |
| R85062 |
T73464 |
T54010 |
arg2Of |
library,on |
| R85070 |
T20304 |
T1345 |
arg1Of |
differences,( |
| R85086 |
T14383 |
T33263 |
arg1Of |
Env,and |
| R851 |
T854 |
T849 |
arg2Of |
and,used |
| R85112 |
T10045 |
T37112 |
arg1Of |
known,also |
| R85123 |
T55061 |
T85286 |
arg2Of |
cells,from |
| R85159 |
T70541 |
T87732 |
arg2Of |
and,can |
| R852 |
T853 |
T850 |
arg1Of |
SARS,the |
| R85204 |
T83032 |
T5512 |
arg1Of |
is,"," |
| R85216 |
T70602 |
T67118 |
arg1Of |
Assemblies,( |
| R8522 |
T94502 |
T64033 |
arg2Of |
Fig. 5,( |
| R85221 |
T20594 |
T55109 |
arg1Of |
residues,solvent-accessible |
| R85227 |
T93591 |
T39186 |
arg2Of |
elevated,found |
| R85283 |
T7777 |
T23472 |
arg1Of |
regions,in |
| R853 |
T853 |
T851 |
arg1Of |
SARS,2P-stabilised |
| R85307 |
T33538 |
T1666 |
arg1Of |
glycosylation,coronavirus |
| R85323 |
T5319 |
T34520 |
arg3Of |
),( |
| R85326 |
T98112 |
T74716 |
arg1Of |
domain,is |
| R85329 |
T68396 |
T92120 |
arg1Of |
MS,analysed |
| R85368 |
T65616 |
T83825 |
arg1Of |
circles,indicate |
| R85372 |
T63927 |
T40801 |
arg1Of |
they,are |
| R85394 |
T99530 |
T60926 |
arg2Of |
analysis,were |
| R85398 |
T70323 |
T14482 |
arg1Of |
proteins,respective |
| R854 |
T853 |
T852 |
arg1Of |
SARS,native-like |
| R85433 |
T30294 |
T11420 |
arg1Of |
densities,shield |
| R85434 |
T93687 |
T31999 |
arg1Of |
",",and |
| R8545 |
T89747 |
T86415 |
arg1Of |
accretion,of |
| R85450 |
T97622 |
T28690 |
arg2Of |
comparisons,disallow |
| R85455 |
T99799 |
T4404 |
arg2Of |
glycoproteins,and |
| R85461 |
T53941 |
T81241 |
arg1Of |
SOSIP.664,for |
| R855 |
T853 |
T854 |
arg1Of |
SARS,and |
| R85546 |
T68640 |
T24930 |
arg1Of |
proteins,S |
| R85552 |
T84155 |
T77249 |
arg1Of |
functions,"," |
| R85556 |
T19959 |
T53841 |
arg2Of |
remaining,while |
| R8557 |
T39941 |
T78537 |
arg2Of |
genes,of |
| R85584 |
T73691 |
T75651 |
arg2Of |
and,of |
| R8559 |
T85741 |
T14842 |
arg2Of |
map,of |
| R856 |
T858 |
T854 |
arg2Of |
antigens,and |
| R85642 |
T83864 |
T58557 |
arg1Of |
whereas,"," |
| R85655 |
T25121 |
T22092 |
arg1Of |
deletions,( |
| R85691 |
T3445 |
T26714 |
arg2Of |
glycosylation,of |
| R857 |
T858 |
T855 |
arg1Of |
antigens,MERS |
| R85720 |
T98112 |
T56881 |
arg1Of |
domain,receptor-binding |
| R858 |
T858 |
T856 |
arg1Of |
antigens,S |
| R85815 |
T80844 |
T83936 |
arg1Of |
networks,that |
| R85823 |
T69932 |
T90504 |
arg2Of |
define,serve |
| R85836 |
T12203 |
T37340 |
arg2Of |
spike,targeting |
| R859 |
T858 |
T857 |
arg1Of |
antigens,protein |
| R85917 |
T12679 |
T70297 |
arg1Of |
CoVs,MERS |
| R85973 |
T90304 |
T58601 |
arg2Of |
Fig. 8,( |
| R860 |
T868 |
T859 |
arg1Of |
described,"," |
| R86027 |
T15871 |
T69209 |
arg1Of |
March,17 |
| R8603 |
T77964 |
T99997 |
arg2Of |
understanding,to |
| R86035 |
T64538 |
T35201 |
arg2Of |
notion,reflected |
| R8606 |
T5495 |
T50640 |
arg2Of |
mutations,and |
| R861 |
T862 |
T860 |
arg1Of |
and,the |
| R86107 |
T32530 |
T45598 |
arg1Of |
are,also |
| R86109 |
T53941 |
T54597 |
arg1Of |
SOSIP.664,but |
| R86127 |
T40801 |
T88580 |
arg1Of |
are,) |
| R86135 |
T46492 |
T30435 |
arg2Of |
and,targeted |
| R86146 |
T51449 |
T69255 |
arg1Of |
proteins,viral |
| R86174 |
T31427 |
T43119 |
arg1Of |
proteins,SARS |
| R862 |
T861 |
T862 |
arg1Of |
design,and |
| R86243 |
T49843 |
T5765 |
arg1Of |
hotspots,were |
| R863 |
T863 |
T862 |
arg2Of |
structures,and |
| R86331 |
T28685 |
T85420 |
arg1Of |
proteins,fusion |
| R86375 |
T35196 |
T48789 |
arg1Of |
shown,in |
| R864 |
T862 |
T864 |
arg1Of |
and,of |
| R8642 |
T92271 |
T76290 |
arg1Of |
rate66,mutation |
| R86433 |
T16112 |
T86019 |
arg1Of |
diversification,Fig. |
| R86434 |
T57322 |
T64664 |
arg2Of |
and,revealed |
| R86473 |
T20304 |
T58234 |
arg1Of |
differences,multiple |
| R86475 |
T68027 |
T55069 |
arg1Of |
level,low |
| R865 |
T858 |
T864 |
arg2Of |
antigens,of |
| R866 |
T858 |
T865 |
arg1Of |
antigens,which |
| R86604 |
T39562 |
T17578 |
arg1Of |
b,3D |
| R86649 |
T54943 |
T82922 |
arg2Of |
coronavirus,on |
| R86686 |
T71776 |
T7784 |
arg1Of |
interactions,that |
| R867 |
T862 |
T866 |
arg1Of |
and,have |
| R868 |
T868 |
T866 |
arg2Of |
described,have |
| R86812 |
T73688 |
T36751 |
arg1Of |
effects,glycan |
| R86836 |
T75679 |
T87940 |
arg2Of |
sequences,and |
| R86859 |
T82693 |
T17765 |
arg1Of |
and,"," |
| R86884 |
T75718 |
T49217 |
arg1Of |
mapping,3 |
| R86898 |
T82356 |
T4452 |
arg1Of |
diversity,a |
| R869 |
T862 |
T867 |
arg1Of |
and,been |
| R86915 |
T13983 |
T78740 |
arg1Of |
arise,that |
| R870 |
T868 |
T867 |
arg2Of |
described,been |
| R87012 |
T82084 |
T26521 |
arg2Of |
S,on |
| R87062 |
T18623 |
T56324 |
arg1Of |
processed,most |
| R87066 |
T30265 |
T57197 |
arg1Of |
reproduced,directly |
| R871 |
T873 |
T868 |
arg1Of |
al.41,described |
| R87124 |
T15871 |
T93347 |
arg2Of |
March,of |
| R8717 |
T58379 |
T16051 |
arg1Of |
target,main |
| R87187 |
T84155 |
T82847 |
arg2Of |
functions,performing |
| R872 |
T862 |
T868 |
arg2Of |
and,described |
| R87205 |
T31709 |
T33845 |
arg2Of |
structure,hidden |
| R87208 |
T64136 |
T33083 |
arg2Of |
dashed,( |
| R8726 |
T11216 |
T96660 |
arg2Of |
reduced,and |
| R87260 |
T49812 |
T85286 |
arg1Of |
particles,from |
| R87289 |
T76130 |
T72556 |
arg1Of |
site,of |
| R87294 |
T84080 |
T57322 |
arg2Of |
changes,and |
| R873 |
T868 |
T869 |
arg1Of |
described,previously |
| R874 |
T873 |
T870 |
arg2Of |
al.41,by |
| R87433 |
T39300 |
T68800 |
arg2Of |
afucosylated,"," |
| R87495 |
T89403 |
T32196 |
arg1Of |
used,In |
| R875 |
T872 |
T871 |
arg1Of |
et,Pallesen |
| R87502 |
T83803 |
T28189 |
arg1Of |
M9,; |
| R87543 |
T99864 |
T9349 |
arg1Of |
5X59,ID |
| R876 |
T873 |
T872 |
arg1Of |
al.41,et |
| R87623 |
T3264 |
T62822 |
arg1Of |
investigated,then |
| R87652 |
T64040 |
T17730 |
arg2Of |
and,across |
| R87676 |
T7969 |
T86415 |
arg2Of |
glycans,of |
| R877 |
T874 |
T875 |
arg1Of |
SARS,"," |
| R87747 |
T28675 |
T51626 |
arg1Of |
sensitive,to |
| R87779 |
T35349 |
T29813 |
arg1Of |
subunits,are |
| R878 |
T876 |
T875 |
arg2Of |
MERS,"," |
| R87857 |
T15804 |
T52826 |
arg1Of |
elicit,upon |
| R87860 |
T15044 |
T29355 |
arg2Of |
and,to |
| R87862 |
T51881 |
T26477 |
arg2Of |
least,Left |
| R879 |
T875 |
T877 |
arg1Of |
",",and |
| R87987 |
T37597 |
T74879 |
arg1Of |
data,SARS |
| R87991 |
T19328 |
T15548 |
arg2Of |
suggest,would |
| R880 |
T880 |
T877 |
arg2Of |
genes,and |
| R88002 |
T3180 |
T62295 |
arg1Of |
analysis,of |
| R88051 |
T68681 |
T20175 |
arg1Of |
knock,out |
| R881 |
T880 |
T878 |
arg1Of |
genes,HKU1 |
| R88101 |
T24662 |
T26633 |
arg1Of |
GPC,the |
| R88109 |
T12587 |
T55529 |
arg2Of |
environment,in |
| R88141 |
T75209 |
T37067 |
arg2Of |
ectodomain52,visualized |
| R882 |
T880 |
T879 |
arg1Of |
genes,S |
| R88211 |
T13208 |
T66915 |
arg1Of |
",",and |
| R883 |
T877 |
T881 |
arg1Of |
and,encode |
| R88310 |
T52275 |
T53697 |
arg1Of |
reveal,in |
| R8832 |
T91376 |
T14852 |
arg1Of |
larger,significantly |
| R88347 |
T16712 |
T80363 |
arg1Of |
domains,receptor-binding |
| R8839 |
T11220 |
T12255 |
arg1Of |
dynamics,glycan |
| R88392 |
T30580 |
T18378 |
arg3Of |
),( |
| R88399 |
T67621 |
T29228 |
arg2Of |
hand,on |
| R884 |
T886 |
T881 |
arg2Of |
;,encode |
| R88458 |
T3262 |
T11057 |
arg1Of |
glycoproteins,analysis |
| R885 |
T885 |
T882 |
arg1Of |
sequons,many |
| R88573 |
T92287 |
T83087 |
arg2Of |
exhibited,revealed |
| R886 |
T885 |
T883 |
arg1Of |
sequons,N-linked |
| R88638 |
T24985 |
T96776 |
arg2Of |
that,of |
| R887 |
T885 |
T884 |
arg1Of |
sequons,glycan |
| R88738 |
T13118 |
T53309 |
arg1Of |
synonymous,non-synonymous |
| R88756 |
T66804 |
T69932 |
arg1Of |
surface,define |
| R88765 |
T39891 |
T26493 |
arg2Of |
core,from |
| R888 |
T885 |
T886 |
arg1Of |
sequons,; |
| R88806 |
T3893 |
T21495 |
arg2Of |
shown,were |
| R88808 |
T2410 |
T8985 |
arg1Of |
sites,the |
| R88814 |
T13983 |
T11037 |
arg2Of |
arise,speculate |
| R88830 |
T66936 |
T73735 |
arg1Of |
number,was |
| R88839 |
T1670 |
T34347 |
arg1Of |
trimming,"," |
| R88856 |
T65162 |
T41593 |
arg1Of |
titres,of |
| R889 |
T890 |
T886 |
arg2Of |
and,; |
| R88912 |
T26227 |
T23601 |
arg1Of |
abundance,the |
| R88932 |
T52131 |
T92018 |
arg2Of |
N-glycans,released |
| R88937 |
T99824 |
T1558 |
arg1Of |
density,glycan |
| R88967 |
T48593 |
T79082 |
arg1Of |
interactions,extensive |
| R88973 |
T33012 |
T69427 |
arg2Of |
Victoria,( |
| R890 |
T887 |
T888 |
arg1Of |
23,"," |
| R89049 |
T60437 |
T28667 |
arg1Of |
total,of |
| R89054 |
T38777 |
T90908 |
arg1Of |
densities,the |
| R89068 |
T20998 |
T77065 |
arg1Of |
regions,the |
| R89069 |
T73605 |
T65049 |
arg2Of |
flexibility,maintaining |
| R8907 |
T81413 |
T68523 |
arg1Of |
SARS,and |
| R891 |
T889 |
T888 |
arg2Of |
23,"," |
| R89109 |
T46398 |
T17171 |
arg1Of |
were,"," |
| R892 |
T888 |
T890 |
arg1Of |
",",and |
| R89282 |
T56245 |
T88998 |
arg2Of |
antibodies,as |
| R893 |
T891 |
T890 |
arg2Of |
29,and |
| R8931 |
T74143 |
T4164 |
arg1Of |
density,may |
| R89372 |
T8652 |
T27352 |
arg1Of |
digested,with |
| R894 |
T886 |
T892 |
arg1Of |
;,"," |
| R89430 |
T75686 |
T84570 |
arg1Of |
proteins,SARS |
| R89466 |
T67026 |
T68704 |
arg1Of |
domains,exist |
| R895 |
T886 |
T893 |
arg1Of |
;,respectively |
| R89512 |
T43620 |
T92642 |
arg3Of |
),( |
| R89552 |
T29672 |
T9596 |
arg1Of |
datasets,of |
| R896 |
T886 |
T894 |
arg1Of |
;,( |
| R897 |
T895 |
T894 |
arg2Of |
Fig. 1a,( |
| R898 |
T896 |
T894 |
arg3Of |
),( |
| R89891 |
T11216 |
T27277 |
arg1Of |
reduced,in |
| R899 |
T899 |
T898 |
arg1Of |
sought,initially |
| R89913 |
T91715 |
T27531 |
arg1Of |
glycoproteins,other |
| R89979 |
T35120 |
T20638 |
arg2Of |
subjected,were |
| R8999 |
T72680 |
T77073 |
arg1Of |
linked,Whether |
| R900 |
T897 |
T899 |
arg1Of |
We,sought |
| R90004 |
T95298 |
T46276 |
arg1Of |
copies,three |
| R90040 |
T52825 |
T13519 |
arg1Of |
glycans,these |
| R90057 |
T3893 |
T10706 |
arg1Of |
shown,however |
| R90066 |
T34122 |
T47078 |
arg1Of |
SARS-CoV-2,possesses |
| R90068 |
T75525 |
T91248 |
arg1Of |
“shield”,glycan |
| R90078 |
T1566 |
T10659 |
arg2Of |
opposed,as |
| R901 |
T902 |
T899 |
arg2Of |
assess,sought |
| R90105 |
T40780 |
T42499 |
arg1Of |
clusters,on |
| R90148 |
T63261 |
T5337 |
arg1Of |
leads,that |
| R90166 |
T2961 |
T30445 |
arg1Of |
had,compared |
| R90176 |
T45573 |
T3633 |
arg3Of |
),( |
| R90190 |
T41193 |
T54555 |
arg1Of |
compositions,at |
| R902 |
T902 |
T900 |
arg1Of |
assess,to |
| R90220 |
T75525 |
T73077 |
arg1Of |
“shield”,the |
| R90259 |
T42487 |
T3483 |
arg2Of |
evaluation,performed |
| R903 |
T902 |
T901 |
arg1Of |
assess,quantitatively |
| R90310 |
T39713 |
T72942 |
arg1Of |
they,can |
| R90371 |
T10448 |
T68645 |
arg1Of |
are,"," |
| R90378 |
T32345 |
T22228 |
arg1Of |
environment,host |
| R904 |
T897 |
T902 |
arg1Of |
We,assess |
| R90435 |
T65868 |
T23843 |
arg1Of |
terms,of |
| R905 |
T904 |
T902 |
arg2Of |
composition,assess |
| R9050 |
T71022 |
T87387 |
arg1Of |
S,and |
| R90505 |
T75679 |
T21364 |
arg1Of |
sequences,gene |
| R90521 |
T84653 |
T49065 |
arg1Of |
proteins,envelope |
| R90522 |
T92910 |
T71146 |
arg2Of |
Residues,colored |
| R90546 |
T16113 |
T79466 |
arg1Of |
panel,Left |
| R90565 |
T37933 |
T36054 |
arg1Of |
and,which |
| R90591 |
T31010 |
T95071 |
arg2Of |
correlation,observed |
| R906 |
T904 |
T903 |
arg1Of |
composition,the |
| R90671 |
T37762 |
T60903 |
arg1Of |
additions,site |
| R907 |
T904 |
T905 |
arg1Of |
composition,of |
| R90709 |
T64543 |
T25999 |
arg1Of |
zoonosis,the |
| R90758 |
T57392 |
T29532 |
arg1Of |
information,can |
| R90788 |
T94871 |
T71413 |
arg1Of |
shield,of |
| R908 |
T907 |
T905 |
arg2Of |
carbohydrate,of |
| R90800 |
T41923 |
T4404 |
arg1Of |
11,and |
| R90824 |
T71146 |
T69312 |
arg1Of |
colored,and |
| R90854 |
T19388 |
T37715 |
arg1Of |
al.51,et |
| R90881 |
T86576 |
T2448 |
arg3Of |
),( |
| R909 |
T907 |
T906 |
arg1Of |
carbohydrate,the |
| R90965 |
T31709 |
T9264 |
arg2Of |
structure,reveal |
| R910 |
T908 |
T909 |
arg1Of |
structures,displayed |
| R9103 |
T65772 |
T84841 |
arg1Of |
abundance,oligomannose |
| R91092 |
T59844 |
T49747 |
arg2Of |
to,according |
| R911 |
T904 |
T909 |
arg2Of |
composition,displayed |
| R91100 |
T46492 |
T46892 |
arg1Of |
and,are |
| R91132 |
T68778 |
T46258 |
arg1Of |
it,would |
| R91159 |
T9382 |
T51534 |
arg1Of |
S,MERS |
| R91171 |
T80516 |
T24089 |
arg1Of |
aid,to |
| R912 |
T909 |
T910 |
arg1Of |
displayed,on |
| R91207 |
T14194 |
T4820 |
arg1Of |
glycosylation,observed |
| R91245 |
T39503 |
T1176 |
arg1Of |
this,may |
| R91250 |
T76651 |
T27352 |
arg2Of |
assortment,with |
| R913 |
T913 |
T910 |
arg2Of |
glycoproteins,on |
| R91304 |
T24146 |
T7451 |
arg1Of |
Proteins,"," |
| R91364 |
T5164 |
T67945 |
arg1Of |
modelling,is |
| R914 |
T913 |
T911 |
arg1Of |
glycoproteins,the |
| R91411 |
T48779 |
T11920 |
arg1Of |
indicated,"," |
| R91435 |
T64790 |
T55283 |
arg1Of |
We,showed51 |
| R915 |
T913 |
T912 |
arg1Of |
glycoproteins,S |
| R91526 |
T41175 |
T50624 |
arg1Of |
strong”56,“evasion |
| R91530 |
T88079 |
T71010 |
arg1Of |
5X58,PDB |
| R91538 |
T79412 |
T82304 |
arg1Of |
is,However |
| R91541 |
T10413 |
T32469 |
arg2Of |
and,of |
| R91588 |
T50771 |
T66305 |
arg1Of |
it,is |
| R916 |
T915 |
T914 |
arg2Of |
glycans,N-linked |
| R91605 |
T65168 |
T64192 |
arg1Of |
content,oligomannose |
| R91639 |
T41193 |
T88928 |
arg1Of |
compositions,of |
| R91640 |
T84269 |
T82701 |
arg1Of |
efficacies,shielding |
| R91669 |
T65417 |
T63529 |
arg1Of |
differ,"," |
| R917 |
T915 |
T916 |
arg1Of |
glycans,were |
| R91717 |
T49009 |
T70456 |
arg1Of |
structure,This |
| R91721 |
T76130 |
T66548 |
arg1Of |
site,DPP4 |
| R91746 |
T16458 |
T55752 |
arg1Of |
dataset52,the |
| R9175 |
T47420 |
T12510 |
arg1Of |
number,the |
| R91771 |
T68027 |
T38898 |
arg1Of |
level,contour |
| R918 |
T919 |
T916 |
arg2Of |
",",were |
| R91807 |
T95182 |
T62794 |
arg1Of |
",",demonstrate |
| R91821 |
T42577 |
T95262 |
arg2Of |
modulation,in |
| R91856 |
T93400 |
T18456 |
arg1Of |
N-linked,Fig. |
| R91860 |
T68738 |
T29834 |
arg1Of |
comparable,within |
| R91871 |
T21302 |
T87387 |
arg2Of |
shields,and |
| R91880 |
T13067 |
T40910 |
arg1Of |
permeating,through |
| R919 |
T919 |
T917 |
arg1Of |
",",enzymatically |
| R9199 |
T53051 |
T61501 |
arg2Of |
Env,"," |
| R920 |
T915 |
T918 |
arg2Of |
glycans,released |
| R92098 |
T89662 |
T88210 |
arg1Of |
S,SARS |
| R921 |
T918 |
T919 |
arg1Of |
released,"," |
| R92116 |
T49864 |
T28659 |
arg1Of |
glycans,hybrid |
| R92134 |
T75718 |
T97068 |
arg1Of |
mapping,of |
| R92159 |
T27860 |
T47196 |
arg2Of |
events,by |
| R92165 |
T99953 |
T34488 |
arg3Of |
),( |
| R92167 |
T47096 |
T17293 |
arg2Of |
b,and |
| R92196 |
T19555 |
T59672 |
arg2Of |
importance,considered |
| R922 |
T923 |
T919 |
arg2Of |
and,"," |
| R9225 |
T5302 |
T90081 |
arg2Of |
clusters,exhibit |
| R923 |
T923 |
T920 |
arg1Of |
and,fluorescently |
| R92325 |
T40508 |
T59664 |
arg1Of |
sites,DPP4 |
| R9235 |
T94571 |
T97123 |
arg2Of |
"procainamide24,45,53",with |
| R92380 |
T56273 |
T6423 |
arg1Of |
map,C3-symmetric |
| R924 |
T915 |
T921 |
arg2Of |
glycans,labelled |
| R92418 |
T41193 |
T52563 |
arg1Of |
compositions,the |
| R92469 |
T43199 |
T65839 |
arg1Of |
diversity,and |
| R925 |
T923 |
T922 |
arg1Of |
and,"," |
| R92510 |
T29095 |
T96495 |
arg2Of |
group,of |
| R92515 |
T24905 |
T80023 |
arg2Of |
area,"," |
| R92524 |
T93138 |
T86575 |
arg1Of |
digested,with |
| R92527 |
T65176 |
T50763 |
arg2Of |
n = 566,( |
| R92531 |
T25884 |
T75654 |
arg1Of |
values,for |
| R92599 |
T67026 |
T24397 |
arg1Of |
domains,receptor-binding |
| R926 |
T921 |
T923 |
arg1Of |
labelled,and |
| R92684 |
T49127 |
T15094 |
arg2Of |
ID,( |
| R927 |
T924 |
T923 |
arg2Of |
subjected,and |
| R92714 |
T15004 |
T14842 |
arg1Of |
region,of |
| R92729 |
T29095 |
T19945 |
arg1Of |
group,each |
| R92766 |
T1661 |
T90570 |
arg2Of |
glycans,of |
| R928 |
T915 |
T924 |
arg2Of |
glycans,subjected |
| R92800 |
T86925 |
T66610 |
arg1Of |
series,oligomannose-type |
| R9284 |
T96751 |
T97449 |
arg3Of |
),( |
| R929 |
T924 |
T925 |
arg1Of |
subjected,to |
| R92973 |
T18965 |
T82634 |
arg1Of |
proteins,and |
| R92976 |
T7550 |
T53210 |
arg1Of |
accumulation,the |
| R930 |
T930 |
T925 |
arg2Of |
chromatography,to |
| R93010 |
T89747 |
T82950 |
arg1Of |
accretion,the |
| R93032 |
T52825 |
T42882 |
arg2Of |
glycans,underprocessed |
| R93062 |
T55814 |
T25906 |
arg2Of |
and,where |
| R93094 |
T13118 |
T78726 |
arg1Of |
synonymous,to |
| R931 |
T930 |
T926 |
arg1Of |
chromatography,hydrophilic |
| R93131 |
T90188 |
T57750 |
arg1Of |
map,of |
| R93165 |
T80263 |
T56636 |
arg1Of |
development,the |
| R932 |
T930 |
T927 |
arg1Of |
chromatography,interaction |
| R93264 |
T92271 |
T95094 |
arg1Of |
rate66,high |
| R93289 |
T84994 |
T23943 |
arg1Of |
processing,the |
| R933 |
T930 |
T928 |
arg1Of |
chromatography,chromatography-ultra-performance |
| R93381 |
T48265 |
T94495 |
arg1Of |
quantities,relative |
| R934 |
T930 |
T929 |
arg1Of |
chromatography,liquid |
| R93413 |
T40498 |
T97839 |
arg2Of |
lack,note |
| R93473 |
T21025 |
T36644 |
arg2Of |
abundances,ascertained |
| R935 |
T930 |
T931 |
arg1Of |
chromatography,( |
| R93509 |
T81297 |
T32584 |
arg1Of |
surface,protein |
| R93551 |
T10324 |
T58404 |
arg1Of |
ratios,i.e. |
| R936 |
T932 |
T931 |
arg2Of |
HILIC-UPLC,( |
| R9362 |
T61553 |
T17900 |
arg1Of |
trypsin,plus |
| R93623 |
T13186 |
T78182 |
arg2Of |
coronaviruses,of |
| R93652 |
T93319 |
T34460 |
arg1Of |
domains,the |
| R9367 |
T86793 |
T61088 |
arg2Of |
epitopes,targeted |
| R937 |
T933 |
T931 |
arg3Of |
),( |
| R93793 |
T50573 |
T85872 |
arg1Of |
and,"," |
| R938 |
T934 |
T935 |
arg1Of |
Treatment,with |
| R93804 |
T93400 |
T81709 |
arg1Of |
N-linked,site-specific |
| R93852 |
T46887 |
T7086 |
arg1Of |
sites,ACE2 |
| R93854 |
T61083 |
T69286 |
arg2Of |
and,calculated |
| R93881 |
T64712 |
T7069 |
arg1Of |
bars,correspond |
| R93882 |
T70489 |
T1909 |
arg1Of |
",","," |
| R939 |
T937 |
T935 |
arg2Of |
H,with |
| R93979 |
T99864 |
T97449 |
arg2Of |
5X59,( |
| R940 |
T937 |
T936 |
arg1Of |
H,endoglycosidase |
| R94025 |
T42122 |
T5756 |
arg1Of |
signal,intensity |
| R94049 |
T40461 |
T21664 |
arg2Of |
chymotrypsin,"," |
| R94067 |
T55295 |
T15659 |
arg1Of |
proteins,class |
| R941 |
T937 |
T938 |
arg1Of |
H,( |
| R942 |
T940 |
T938 |
arg2Of |
H,( |
| R94202 |
T34645 |
T39600 |
arg1Of |
",","," |
| R94234 |
T14034 |
T34347 |
arg2Of |
processing,"," |
| R94248 |
T93591 |
T6773 |
arg1Of |
elevated,that |
| R94251 |
T84232 |
T65100 |
arg1Of |
"lectins47,48",that |
| R94261 |
T35489 |
T78652 |
arg1Of |
S,( |
| R94272 |
T85155 |
T10448 |
arg2Of |
able,are |
| R94280 |
T25542 |
T79412 |
arg1Of |
coverage,is |
| R94295 |
T3010 |
T73014 |
arg3Of |
),( |
| R943 |
T941 |
T938 |
arg3Of |
),( |
| R94313 |
T13068 |
T77011 |
arg1Of |
functionality,receptor-binding |
| R94318 |
T98636 |
T65839 |
arg2Of |
dN/dS,and |
| R94357 |
T84155 |
T70958 |
arg1Of |
functions,including |
| R94366 |
T75405 |
T78209 |
arg1Of |
differences,the |
| R94377 |
T14361 |
T38180 |
arg1Of |
outbreak,viral |
| R94385 |
T95787 |
T76751 |
arg1Of |
number,the |
| R944 |
T940 |
T939 |
arg1Of |
H,Endo |
| R94401 |
T46773 |
T30799 |
arg2Of |
sialylation,and |
| R94455 |
T3102 |
T34718 |
arg2Of |
expected,As |
| R94463 |
T62840 |
T73202 |
arg2Of |
end,To |
| R945 |
T934 |
T942 |
arg1Of |
Treatment,revealed |
| R94511 |
T37933 |
T54589 |
arg1Of |
and,underscores |
| R94531 |
T78585 |
T78948 |
arg2Of |
2.82,with |
| R94545 |
T94939 |
T86648 |
arg1Of |
infection,or |
| R94567 |
T89162 |
T27010 |
arg1Of |
as,as |
| R9457 |
T28413 |
T9951 |
arg1Of |
targets,located |
| R94598 |
T8574 |
T91452 |
arg1Of |
highlighted,"," |
| R946 |
T944 |
T942 |
arg2Of |
population,revealed |
| R94608 |
T61083 |
T3167 |
arg1Of |
and,"," |
| R94625 |
T27050 |
T56676 |
arg1Of |
microscopy,cryo-electron |
| R94627 |
T13646 |
T96398 |
arg1Of |
glycoprotein,each |
| R94664 |
T11314 |
T15501 |
arg2Of |
Env,in |
| R94669 |
T80082 |
T99831 |
arg1Of |
glycopeptides,"," |
| R947 |
T944 |
T943 |
arg1Of |
population,a |
| R94726 |
T79346 |
T67690 |
arg1Of |
route,a |
| R94760 |
T65635 |
T5712 |
arg2Of |
lpf,( |
| R94768 |
T7775 |
T35432 |
arg2Of |
residues,with |
| R948 |
T944 |
T945 |
arg1Of |
population,( |
| R94826 |
T80516 |
T31245 |
arg1Of |
aid,from |
| R94853 |
T7534 |
T27520 |
arg1Of |
limits,in |
| R949 |
T948 |
T945 |
arg2Of |
%,( |
| R94942 |
T43233 |
T31301 |
arg1Of |
5X58,and |
| R94953 |
T92859 |
T85418 |
arg3Of |
),( |
| R950 |
T957 |
T945 |
arg3Of |
),( |
| R95052 |
T37067 |
T22530 |
arg1Of |
visualized,at |
| R95057 |
T60790 |
T18721 |
arg1Of |
domains,the |
| R951 |
T948 |
T946 |
arg1Of |
%,SARS |
| R95102 |
T12246 |
T58601 |
arg1Of |
sites,( |
| R95164 |
T77800 |
T37387 |
arg1Of |
analysis,from |
| R952 |
T948 |
T947 |
arg1Of |
%,32.2 |
| R95204 |
T52275 |
T93380 |
arg2Of |
reveal,and |
| R95247 |
T78856 |
T96785 |
arg1Of |
research,vaccine |
| R95251 |
T93319 |
T23715 |
arg1Of |
domains,are |
| R95269 |
T84168 |
T46581 |
arg2Of |
glycans,of |
| R953 |
T948 |
T949 |
arg1Of |
%,; |
| R95337 |
T63927 |
T67674 |
arg1Of |
they,comparable |
| R95353 |
T29223 |
T90865 |
arg2Of |
glycans,by |
| R95367 |
T72680 |
T99216 |
arg1Of |
linked,unknown |
| R954 |
T952 |
T949 |
arg2Of |
%,; |
| R95483 |
T99824 |
T44869 |
arg1Of |
density,in |
| R95498 |
T51670 |
T64487 |
arg1Of |
glycosylated,fully |
| R955 |
T952 |
T950 |
arg1Of |
%,MERS |
| R95535 |
T97022 |
T63910 |
arg3Of |
),( |
| R95558 |
T93082 |
T93681 |
arg2Of |
adding,HAs |
| R956 |
T952 |
T951 |
arg1Of |
%,33.8 |
| R95696 |
T2440 |
T81945 |
arg1Of |
glycoproteins,MERS |
| R957 |
T948 |
T953 |
arg1Of |
%,"," |
| R95719 |
T18666 |
T78058 |
arg1Of |
spectrometry,in-line |
| R95749 |
T27449 |
T55010 |
arg2Of |
proteins,on |
| R95788 |
T76109 |
T52952 |
arg1Of |
undergoing,compared |
| R958 |
T956 |
T953 |
arg2Of |
%,"," |
| R9580 |
T54076 |
T90081 |
arg1Of |
and,exhibit |
| R95802 |
T10907 |
T6763 |
arg1Of |
Hybrid,Hybrid |
| R95810 |
T65172 |
T24472 |
arg1Of |
domain,of |
| R95827 |
T47420 |
T7804 |
arg1Of |
number,of |
| R959 |
T956 |
T954 |
arg1Of |
%,HKU1 |
| R95941 |
T20594 |
T87805 |
arg1Of |
residues,be |
| R95989 |
T80657 |
T99370 |
arg1Of |
protein,exhibits |
| R95997 |
T79677 |
T9355 |
arg1Of |
maps,3D |
| R960 |
T956 |
T955 |
arg1Of |
%,25.0 |
| R9602 |
T99144 |
T62580 |
arg1Of |
blue,light |
| R96045 |
T68539 |
T1963 |
arg2Of |
glycans,implicated |
| R96046 |
T1822 |
T98108 |
arg1Of |
is,"," |
| R9606 |
T31709 |
T97881 |
arg1Of |
structure,of |
| R96064 |
T83454 |
T45232 |
arg1Of |
pathogens,the |
| R96070 |
T38606 |
T52914 |
arg1Of |
GPC,"," |
| R96091 |
T76109 |
T71210 |
arg2Of |
undergoing,hypothesized |
| R961 |
T944 |
T958 |
arg1Of |
population,of |
| R96110 |
T99472 |
T38302 |
arg1Of |
constraints,functional |
| R96137 |
T25443 |
T89667 |
arg2Of |
MERS,characterized |
| R96156 |
T27449 |
T92344 |
arg1Of |
proteins,S |
| R962 |
T961 |
T958 |
arg2Of |
glycans,of |
| R96209 |
T72350 |
T71605 |
arg1Of |
consisting,of |
| R96223 |
T86793 |
T94778 |
arg1Of |
epitopes,as |
| R96288 |
T77242 |
T4847 |
arg1Of |
S,MERS |
| R963 |
T961 |
T959 |
arg2Of |
glycans,underprocessed |
| R96360 |
T26472 |
T58672 |
arg2Of |
subunit,on |
| R964 |
T961 |
T960 |
arg1Of |
glycans,oligomannose-type |
| R96485 |
T54715 |
T15304 |
arg1Of |
glycans,were |
| R965 |
T961 |
T962 |
arg1Of |
glycans,( |
| R96503 |
T27860 |
T30054 |
arg1Of |
events,spillover |
| R96524 |
T30435 |
T59632 |
arg2Of |
targeted,unable |
| R966 |
T963 |
T962 |
arg2Of |
Fig. 1b,( |
| R96677 |
T84994 |
T52429 |
arg1Of |
processing,glycan-influenced |
| R967 |
T964 |
T962 |
arg3Of |
),( |
| R96790 |
T11163 |
T6955 |
arg1Of |
cells,apart |
| R96796 |
T55408 |
T45120 |
arg1Of |
ratio,of |
| R96797 |
T64492 |
T50640 |
arg1Of |
",",and |
| R96798 |
T11163 |
T61720 |
arg1Of |
cells,HEK293F |
| R96799 |
T39465 |
T94895 |
arg1Of |
“shields”,respective |
| R968 |
T966 |
T965 |
arg1Of |
observation,This |
| R9682 |
T75209 |
T84496 |
arg1Of |
ectodomain52,S |
| R96826 |
T29095 |
T83205 |
arg1Of |
group,glycan |
| R969 |
T966 |
T967 |
arg1Of |
observation,of |
| R96918 |
T17645 |
T70799 |
arg2Of |
sites,of |
| R96920 |
T47272 |
T62341 |
arg1Of |
fusion,membrane |
| R96993 |
T53941 |
T97382 |
arg1Of |
SOSIP.664,) |
| R970 |
T972 |
T967 |
arg2Of |
glycans,of |
| R97033 |
T81231 |
T40406 |
arg1Of |
considered,and |
| R97035 |
T48849 |
T44931 |
arg1Of |
ecology,transmission |
| R971 |
T972 |
T968 |
arg1Of |
glycans,both |
| R97100 |
T74594 |
T74197 |
arg1Of |
structure,prefusion |
| R97141 |
T81297 |
T83557 |
arg1Of |
surface,the |
| R9715 |
T56838 |
T72210 |
arg1Of |
protease,alpha-lytic |
| R97186 |
T11869 |
T1640 |
arg1Of |
sites,N-linked |
| R97191 |
T11359 |
T98634 |
arg1Of |
consist,"," |
| R972 |
T972 |
T969 |
arg1Of |
glycans,complex |
| R97236 |
T21025 |
T11498 |
arg1Of |
abundances,were |
| R97244 |
T87267 |
T99218 |
arg2Of |
glycans,from |
| R97251 |
T93372 |
T85155 |
arg2Of |
accommodate,able |
| R97277 |
T22031 |
T84609 |
arg1Of |
analysis,glycopeptide |
| R97294 |
T18793 |
T22092 |
arg3Of |
),( |
| R973 |
T969 |
T970 |
arg1Of |
complex,and |
| R97315 |
T93669 |
T16192 |
arg2Of |
compositions,using |
| R9733 |
T26227 |
T71479 |
arg1Of |
abundance,overall |
| R97349 |
T86648 |
T2480 |
arg2Of |
or,following |
| R974 |
T971 |
T970 |
arg2Of |
oligomannose-type,and |
| R975 |
T972 |
T971 |
arg1Of |
glycans,oligomannose-type |
| R97505 |
T72666 |
T34571 |
arg1Of |
approach,global |
| R976 |
T966 |
T973 |
arg1Of |
observation,reveals |
| R97660 |
T46478 |
T75654 |
arg2Of |
domain,for |
| R977 |
T982 |
T973 |
arg2Of |
processed,reveals |
| R97730 |
T91020 |
T50998 |
arg1Of |
Man9GlcNAc2,to |
| R97765 |
T11718 |
T88501 |
arg1Of |
higher,significantly |
| R97784 |
T70902 |
T95182 |
arg1Of |
plays,"," |
| R978 |
T982 |
T974 |
arg1Of |
processed,that |
| R97807 |
T39600 |
T19879 |
arg1Of |
",","," |
| R97812 |
T20910 |
T32211 |
arg2Of |
antibodies,elicit |
| R97825 |
T3337 |
T52236 |
arg2Of |
shield51,with |
| R97857 |
T86129 |
T93372 |
arg1Of |
viruses,accommodate |
| R979 |
T976 |
T975 |
arg1Of |
majority,the |
| R9791 |
T66354 |
T6297 |
arg1Of |
shielding,is |
| R97915 |
T73292 |
T67434 |
arg1Of |
analysis,of |
| R9793 |
T10907 |
T85300 |
arg2Of |
Hybrid,( |
| R980 |
T976 |
T977 |
arg1Of |
majority,of |
| R98007 |
T2696 |
T8376 |
arg1Of |
occluded,not |
| R98030 |
T78031 |
T72214 |
arg2Of |
Fig. 3b,( |
| R981 |
T979 |
T977 |
arg2Of |
glycans,of |
| R98141 |
T28342 |
T39391 |
arg1Of |
and,"," |
| R98154 |
T18104 |
T34570 |
arg1Of |
terms,of |
| R98159 |
T8708 |
T77386 |
arg1Of |
importance,the |
| R9817 |
T98975 |
T23520 |
arg1Of |
majority,of |
| R9818 |
T9951 |
T30887 |
arg2Of |
located,are |
| R98187 |
T72184 |
T26493 |
arg1Of |
extending,from |
| R982 |
T979 |
T978 |
arg1Of |
glycans,N-linked |
| R98202 |
T70460 |
T30751 |
arg1Of |
clustering,was |
| R98204 |
T95495 |
T72291 |
arg3Of |
grey,colored |
| R98228 |
T1949 |
T69745 |
arg1Of |
diversity,residue |
| R98278 |
T8512 |
T97617 |
arg1Of |
coronaviruses,biomedically |
| R98281 |
T51281 |
T32640 |
arg1Of |
as,such |
| R98282 |
T15044 |
T80897 |
arg1Of |
and,is |
| R98287 |
T61150 |
T11703 |
arg1Of |
A1,to |
| R983 |
T976 |
T980 |
arg1Of |
majority,can |
| R98318 |
T73857 |
T37469 |
arg1Of |
convolved,and |
| R98364 |
T81349 |
T39330 |
arg2Of |
glycosylation,of |
| R984 |
T982 |
T980 |
arg2Of |
processed,can |
| R98488 |
T46357 |
T51205 |
arg2Of |
differences,observed |
| R985 |
T976 |
T981 |
arg1Of |
majority,be |
| R98501 |
T97014 |
T28787 |
arg2Of |
response,of |
| R986 |
T982 |
T981 |
arg2Of |
processed,be |
| R98678 |
T28342 |
T67259 |
arg2Of |
and,on |
| R98692 |
T8049 |
T48803 |
arg2Of |
and,of |
| R987 |
T976 |
T982 |
arg2Of |
majority,processed |
| R98710 |
T93591 |
T90961 |
arg1Of |
elevated,at |
| R98729 |
T15993 |
T46581 |
arg1Of |
presence,of |
| R988 |
T982 |
T983 |
arg1Of |
processed,"," |
| R98810 |
T51881 |
T18623 |
arg2Of |
least,processed |
| R98814 |
T42839 |
T28589 |
arg2Of |
building,for |
| R98825 |
T72037 |
T77577 |
arg2Of |
most,observed |
| R98876 |
T40508 |
T52910 |
arg1Of |
sites,and |
| R989 |
T982 |
T984 |
arg1Of |
processed,although |
| R98907 |
T16113 |
T48820 |
arg1Of |
panel,a |
| R98954 |
T35201 |
T59288 |
arg2Of |
reflected,is |
| R98963 |
T80657 |
T67286 |
arg1Of |
protein,viral |
| R98976 |
T58744 |
T19935 |
arg1Of |
quality,sufficient |
| R98997 |
T38777 |
T13008 |
arg1Of |
densities,of |
| R990 |
T986 |
T984 |
arg2Of |
is,although |
| R99001 |
T62794 |
T28846 |
arg1Of |
demonstrate,To |
| R99054 |
T99144 |
T50978 |
arg2Of |
blue,in |
| R9907 |
T3262 |
T30000 |
arg1Of |
glycoproteins,glycan |
| R9909 |
T96185 |
T84923 |
arg1Of |
"GPC24,31,34,36,45,46",LASV |
| R991 |
T985 |
T986 |
arg1Of |
there,is |
| R99133 |
T43250 |
T30395 |
arg2Of |
results,captures |
| R99138 |
T68424 |
T76564 |
arg1Of |
We,performed |
| R99157 |
T67622 |
T92542 |
arg2Of |
values,of |
| R99163 |
T84155 |
T29264 |
arg1Of |
functions,primary |
| R99168 |
T63130 |
T89986 |
arg1Of |
surface,the |
| R992 |
T988 |
T986 |
arg2Of |
processing,is |
| R99203 |
T11359 |
T57335 |
arg1Of |
consist,For |
| R99255 |
T29096 |
T93372 |
arg2Of |
modifications,accommodate |
| R993 |
T988 |
T987 |
arg1Of |
processing,limited |
| R99316 |
T69491 |
T68738 |
arg1Of |
estimates,comparable |
| R99324 |
T93327 |
T21412 |
arg2Of |
this,plotted |
| R99327 |
T17900 |
T82693 |
arg2Of |
plus,and |
| R99353 |
T13646 |
T53031 |
arg1Of |
glycoprotein,respective |
| R99358 |
T95681 |
T10473 |
arg1Of |
glycosylated,fully |
| R99374 |
T44303 |
T9331 |
arg1Of |
diversity,amino-acid |
| R994 |
T988 |
T989 |
arg1Of |
processing,at |
| R99409 |
T19064 |
T16401 |
arg1Of |
HIV,and |
| R99431 |
T19047 |
T80136 |
arg1Of |
analysis,Comparative |
| R99455 |
T82481 |
T35913 |
arg1Of |
subunit,the |
| R99458 |
T32211 |
T66481 |
arg1Of |
elicit,Although |
| R99470 |
T45372 |
T96797 |
arg1Of |
tempting,However |
| R99471 |
T86172 |
T28589 |
arg1Of |
necessary,for |
| R995 |
T991 |
T989 |
arg2Of |
sites,at |
| R99511 |
T19047 |
T52944 |
arg1Of |
analysis,of |
| R99542 |
T93291 |
T10413 |
arg1Of |
filtering,and |
| R99568 |
T84080 |
T83739 |
arg1Of |
changes,in |
| R996 |
T991 |
T990 |
arg1Of |
sites,specific |
| R99635 |
T88912 |
T28846 |
modOf |
compared,To |
| R99636 |
T65162 |
T39172 |
arg1Of |
titres,high |
| R99688 |
T30346 |
T55641 |
arg2Of |
sites,of |
| R997 |
T991 |
T992 |
arg1Of |
sites,across |
| R998 |
T995 |
T992 |
arg2Of |
proteins,across |
| R99827 |
T91843 |
T69590 |
arg1Of |
performed,As |
| R99845 |
T10448 |
T73121 |
arg2Of |
are,whereas |
| R999 |
T995 |
T993 |
arg1Of |
proteins,the |