| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T171 |
0-5 |
PR:000036008 |
denotes |
Ang I |
| T172 |
62-68 |
PR:000036009 |
denotes |
Ang II |
| T98730 |
69-73 |
PR:000036013 |
denotes |
by A |
| T86736 |
80-84 |
PR:000003622;G_3;PG_10 |
denotes |
ike |
| T173 |
89-94 |
PR:000036008 |
denotes |
Ang I |
| T174 |
115-119 |
PR:000036012 |
denotes |
Ang1 |
| T175 |
125-129 |
PR:000003622;G_3;PG_10 |
denotes |
ACE2 |
| T89530 |
153-158 |
PR:000036013 |
denotes |
Ang |
| T176 |
154-160 |
PR:000036009 |
denotes |
Ang II |
| T177 |
177-182 |
PR:000036013 |
denotes |
Ang 1 |
| T178 |
193-197 |
PR:000003622;G_3;PG_10 |
denotes |
ACE2 |
| T48188 |
197-202 |
PR:000036008 |
denotes |
(17) |
| T179 |
204-209 |
PR:000036013 |
denotes |
Ang1- |
| T41061 |
222-228 |
PR:000036012 |
denotes |
of an |
| T180 |
226-243 |
CHEBI:67079;CHEBI:67079 |
denotes |
anti-inflammatory |
| T94791 |
266-276 |
PR:000001898 |
denotes |
tory, and |
| T37488 |
311-316 |
PR:000013883 |
denotes |
ed by |
| T309 |
354-358 |
G_3;PG_10;PR:000003622 |
denotes |
Mas |
| T181 |
355-358 |
PR:000001563 |
denotes |
Mas |
| T310 |
359-363 |
PR:000036013 |
denotes |
rece |
| T311 |
374-384 |
GO:0065007 |
denotes |
,27). Ang1 |
| T182 |
380-386 |
PR:000036013 |
denotes |
Ang1-7 |
| T312 |
385-400 |
CHEBI:2720;CHEBI:2720 |
denotes |
7 may be produc |
| T183 |
417-422 |
PR:000036008 |
denotes |
Ang I |
| T313 |
417-430 |
PR:000036008 |
denotes |
Ang I through |
| T314 |
432-437 |
PR:000036008 |
denotes |
he al |
| T315 |
443-448 |
PR:000013883 |
denotes |
ive p |
| T316 |
450-455 |
PR:000036008 |
denotes |
hways |
| T317 |
472-480 |
PR:000036009 |
denotes |
metallo |
| T184 |
490-500 |
PR:000001898 |
denotes |
neprilysin |
| T185 |
518-524 |
PR:000036012 |
denotes |
Ang1-9 |
| T186 |
528-534 |
PR:000036013 |
denotes |
Ang1-7 |
| T318 |
533-543 |
MOP:0000619 |
denotes |
7 via ACE, |
| T319 |
544-554 |
CHEBI:3165;CHEBI:3165 |
denotes |
although a |
| T320 |
573-582 |
CHEBI:25212;CHEBI:25212 |
denotes |
ower effi |
| T187 |
595-602 |
SO:0000704 |
denotes |
Genetic |
| T188 |
637-641 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T321 |
640-646 |
PR:000036009 |
denotes |
2 as a |
| T322 |
663-669 |
PR:000036009 |
denotes |
ator o |
| T189 |
671-685 |
UBERON:0004535 |
denotes |
cardiovascular |
| T323 |
709-720 |
CHEBI:27584;CHEBI:27584 |
denotes |
focused on |
| T190 |
724-734 |
GO:0065007 |
denotes |
regulation |
| T191 |
738-742 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T324 |
740-755 |
UBERON:0001236 |
denotes |
E2 in cardiac m |
| T192 |
746-753 |
UBERON:0000948;CL:0000746 |
denotes |
cardiac |
| T193 |
754-762 |
CL:0000746 |
denotes |
myocytes |
| T194 |
767-774 |
UBERON:0000948;CL:0002548 |
denotes |
cardiac |
| T195 |
775-786 |
CL:0002548 |
denotes |
fibroblasts |
| T325 |
800-808 |
UBERON:0002198 |
denotes |
ated tha |
| T326 |
810-821 |
CHEBI:27584;CHEBI:27584 |
denotes |
although An |
| T196 |
819-825 |
PR:000036009 |
denotes |
Ang II |
| T327 |
832-840 |
GO:0016020 |
denotes |
icantly |
| T328 |
841-845 |
G_3;PG_10;PR:000003622 |
denotes |
educ |
| T329 |
846-856 |
GO:0010467 |
denotes |
d ACE2 act |
| T197 |
848-852 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T330 |
858-868 |
UBERON:0001986;PR:000006897 |
denotes |
ity and do |
| T331 |
868-870 |
PR:000006897 |
denotes |
wn |
| T198 |
880-884 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T332 |
880-893 |
PR:000036013 |
denotes |
ACE2 mRNA in |
| T199 |
893-900 |
UBERON:0000948;CL:0000746 |
denotes |
cardiac |
| T333 |
897-901 |
PR:000036013 |
denotes |
iac |
| T200 |
901-909 |
CL:0000746 |
denotes |
myocytes |
| T334 |
909-922 |
GO:0005576 |
denotes |
, it only red |
| T201 |
927-931 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T335 |
930-939 |
GO:0065007 |
denotes |
2 activit |
| T202 |
944-955 |
CL:0000057 |
denotes |
fibroblasts |
| T336 |
954-958 |
PR:000000103 |
denotes |
s (2 |
| T203 |
965-973 |
CL:0000187 |
denotes |
myocytes |
| T337 |
969-975 |
PR:000036009 |
denotes |
ytes, |
| T204 |
975-985 |
UBERON:0001986 |
denotes |
endothelin |
| T205 |
1022-1026 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T338 |
1039-1043 |
PR:000036013 |
denotes |
ion |
| T339 |
1050-1054 |
PR:000003622;G_3;PG_10 |
denotes |
his |
| T206 |
1067-1071 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T207 |
1080-1086 |
PR:000036009 |
denotes |
Ang II |
| T208 |
1090-1094 |
PR:000006897 |
denotes |
ET-1 |
| T209 |
1110-1120 |
CHEBI:35222;CHEBI:35222 |
denotes |
inhibitors |
| T340 |
1123-1128 |
PR:000036013 |
denotes |
mito |
| T210 |
1124-1131 |
CHEBI:52290;CHEBI:52290;PR:000000103 |
denotes |
mitogen |
| T211 |
1131-1158 |
PR:000000103 |
denotes |
-activated protein kinase 1 |
| T212 |
1160-1165 |
PR:000000103 |
denotes |
MAPK1 |
| T341 |
1167-1172 |
PR:000036008 |
denotes |
whic |
| T213 |
1189-1195 |
PR:000036009 |
denotes |
Ang II |
| T342 |
1192-1198 |
PR:000036012 |
denotes |
II an |
| T214 |
1200-1204 |
PR:000006897 |
denotes |
ET-1 |
| T215 |
1214-1227 |
GO:0005576 |
denotes |
extracellular |
| T216 |
1235-1244 |
GO:0065007 |
denotes |
regulated |
| T343 |
1235-1245 |
PR:000001898 |
denotes |
regulated |
| T217 |
1253-1256 |
PR:000007130 |
denotes |
ERK |
| T218 |
1259-1263 |
PR:000000103 |
denotes |
ERK2 |
| T219 |
1274-1278 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T344 |
1280-1285 |
PR:000013883 |
denotes |
29). |
| T9018 |
1306-1311 |
G_3;PG_10;PR:000003622 |
denotes |
murin |
| T220 |
1306-1312 |
NCBITaxon:39107 |
denotes |
murine |
| T63740 |
1312-1322 |
GO:0065007 |
denotes |
studies s |
| T78761 |
1327-1341 |
UBERON:0004535 |
denotes |
Ang II−mediat |
| T221 |
1328-1334 |
PR:000036009 |
denotes |
Ang II |
| T222 |
1352-1360 |
GO:0016020 |
denotes |
membrane |
| T223 |
1367-1380 |
CL:0000746 |
denotes |
cardiomyocyte |
| T224 |
1381-1385 |
PR:000003622;G_3;PG_10 |
denotes |
ACE2 |
| T29306 |
1390-1404 |
UBERON:0004535 |
denotes |
elated with th |
| T37860 |
1418-1428 |
GO:0065007 |
denotes |
of TACE/A |
| T225 |
1427-1433 |
PR:000001279 |
denotes |
ADAM17 |
| T4521 |
1437-1447 |
CHEBI:35222;CHEBI:35222 |
denotes |
ivity, whi |
| T226 |
1469-1472 |
PR:000001251 |
denotes |
AT1 |
| T227 |
1497-1504 |
UBERON:0000948;CL:0002548 |
denotes |
Cardiac |
| T228 |
1505-1516 |
CL:0002548 |
denotes |
fibroblasts |
| T92757 |
1514-1528 |
UBERON:0004535 |
denotes |
ts and coronar |
| T229 |
1521-1529 |
UBERON:0005985;CL:0002364 |
denotes |
coronary |
| T230 |
1530-1541 |
UBERON:0001986;CL:0000115 |
denotes |
endothelial |
| T231 |
1542-1547 |
CL:0000115 |
denotes |
cells |
| T232 |
1553-1560 |
GO:0010467 |
denotes |
express |
| T233 |
1561-1565 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T234 |
1570-1574 |
PR:000001279 |
denotes |
TACE |
| T57057 |
1586-1591 |
PR:000013883 |
denotes |
ecipr |
| T50692 |
1628-1644 |
SP_7 |
denotes |
ll types as well |
| T26520 |
1646-1659 |
PR:000036008 |
denotes |
31,32). Ang I |
| T235 |
1654-1660 |
PR:000036009 |
denotes |
Ang II |
| T11517 |
1661-1666 |
PR:000036008 |
denotes |
activ |
| T49885 |
1684-1690 |
PR:000036009 |
denotes |
signa |
| T236 |
1717-1720 |
PR:000045382 |
denotes |
PKC |
| T237 |
1725-1729 |
PR:000009197 |
denotes |
JAK2 |
| T238 |
1730-1735 |
PR:000002089 |
denotes |
STAT3 |
| T78357 |
1764-1774 |
CHEBI:35222;CHEBI:35222 |
denotes |
sults in m |
| T239 |
1773-1783 |
UBERON:0002349 |
denotes |
myocardial |
| T32486 |
1808-1814 |
PR:000036009 |
denotes |
d fibr |
| T30438 |
1836-1840 |
PR:000001251 |
denotes |
of |
| T240 |
1840-1844 |
PR:000036013 |
denotes |
Ang1 |
| T241 |
1865-1871 |
SO:0000417 |
denotes |
domain |
| T84915 |
1868-1884 |
UBERON:0002053 |
denotes |
ain also inhibit |
| T242 |
1890-1901 |
GO:0006508 |
denotes |
proteolytic |
| T14662 |
1892-1907 |
UBERON:0001236 |
denotes |
oteolytic funct |
| T3622 |
1922-1933 |
CHEBI:27584;CHEBI:27584 |
denotes |
enzyme and |
| T2367 |
1959-1976 |
CHEBI:25354;CHEBI:25354 |
denotes |
on (34). Studies |
| T243 |
1979-1984 |
SP_6;NCBITaxon:9606 |
denotes |
human |
| T70131 |
1998-2003 |
CHEBI:15377;CHEBI:15377 |
denotes |
cardi |
| T244 |
1998-2005 |
UBERON:0000948 |
denotes |
cardiac |
| T245 |
2006-2012 |
UBERON:0000479 |
denotes |
tissue |
| T246 |
2017-2023 |
UBERON:0001969 |
denotes |
plasma |
| T247 |
2031-2035 |
PR:000036013 |
denotes |
Ang1 |
| T22478 |
2033-2037 |
CHEBI:24866;CHEBI:24866 |
denotes |
g1-7 |
| T53819 |
2068-2085 |
CHEBI:25354;CHEBI:25354 |
denotes |
han Ang I, which |
| T248 |
2072-2077 |
PR:000036008 |
denotes |
Ang I |
| T50077 |
2086-2106 |
CHEBI:48561;CHEBI:48561 |
denotes |
uggests the inhibito |
| T249 |
2120-2124 |
PR:000036013 |
denotes |
Ang1 |
| T85097 |
2135-2143 |
UBERON:0002198 |
denotes |
ay contr |
| T97767 |
2145-2151 |
PR:000036009 |
denotes |
ute to |
| T250 |
2198-2202 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T62349 |
2204-2209 |
CHEBI:15377;CHEBI:15377 |
denotes |
nocko |
| T251 |
2212-2216 |
NCBITaxon:10088 |
denotes |
mice |
| T252 |
2222-2228 |
PR:000036009 |
denotes |
Ang II |
| T2176 |
2237-2244 |
UBERON:0000479 |
denotes |
and re |
| T253 |
2254-2258 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T254 |
2279-2283 |
PR:000000104 |
denotes |
ERK1 |
| T255 |
2287-2291 |
PR:000009197 |
denotes |
JAK2 |
| T256 |
2292-2297 |
PR:000002089 |
denotes |
STAT3 |
| T257 |
2303-2306 |
PR:000045382;GO:0000187 |
denotes |
PKC |
| T70273 |
2307-2315 |
MOP:0000568 |
denotes |
signalin |
| T258 |
2307-2316 |
GO:0000165 |
denotes |
signaling |
| T88849 |
2328-2337 |
GO:0006915 |
denotes |
nd was at |
| T259 |
2385-2391 |
PR:000036009 |
denotes |
Ang II |
| T260 |
2400-2410 |
UBERON:0002349 |
denotes |
myocardial |
| T55720 |
2421-2424 |
CHEBI:37886;CHEBI:37886;PR:000036009 |
denotes |
y a |
| T28600 |
2425-2427 |
PR:000036009 |
denotes |
d |
| T83802 |
2439-2443 |
PR:000001251 |
denotes |
imp |
| T53803 |
2445-2451 |
PR:000036009 |
denotes |
vement |
| T72294 |
2477-2490 |
PR:000036013 |
denotes |
(33). Other s |
| T20825 |
2494-2499 |
PR:000036013 |
denotes |
es hi |
| T14954 |
2507-2511 |
PR:000003622;G_3;PG_10 |
denotes |
d th |
| T261 |
2525-2529 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T262 |
2530-2534 |
PR:000036013 |
denotes |
Ang1 |
| T39929 |
2533-2536 |
PR:000001563 |
denotes |
1-7 |
| T263 |
2549-2559 |
GO:0065007 |
denotes |
modulating |
| T264 |
2564-2574 |
GO:0010467 |
denotes |
expression |
| T49406 |
2589-2593 |
G_3;PG_10;PR:000003622 |
denotes |
ator |
| T29031 |
2594-2598 |
PR:000036013 |
denotes |
cyt |
| T265 |
2614-2619 |
PR:000000134 |
denotes |
TNF-α |
| T266 |
2642-2646 |
PR:000001393 |
denotes |
IL-6 |
| T267 |
2648-2656 |
CL:0000576;PR:000002122 |
denotes |
monocyte |
| T268 |
2657-2682 |
PR:000002122 |
denotes |
chemoattractant protein-1 |
| T97645 |
2665-2670 |
PR:000013883 |
denotes |
racta |
| T269 |
2688-2716 |
PR:000000046 |
denotes |
transforming growth factor-β |
| T54224 |
2697-2701 |
PR:000001251 |
denotes |
ing |
| T94906 |
2706-2710 |
PR:000003622;G_3;PG_10 |
denotes |
h fa |
| T270 |
2720-2727 |
UBERON:0000948 |
denotes |
cardiac |
| T80849 |
2724-2730 |
PR:000036009 |
denotes |
iac an |
| T271 |
2735-2739 |
UBERON:0002048 |
denotes |
lung |
| T57333 |
2742-2746 |
PR:000001251 |
denotes |
bros |
| T272 |
2750-2759 |
UBERON:0002048 |
denotes |
pulmonary |
| T66538 |
2770-2774 |
PR:000003622;G_3;PG_10 |
denotes |
on, |
| T53794 |
2832-2836 |
G_3;PG_10;PR:000003622 |
denotes |
). |
| T273 |
2853-2857 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T274 |
2858-2862 |
PR:000036013 |
denotes |
Ang1 |
| T275 |
2865-2868 |
PR:000001563 |
denotes |
Mas |
| T276 |
2874-2900 |
GO:0065007 |
denotes |
Regulation
Angiotensinogen |
| T49835 |
2876-2882 |
PR:000036009 |
denotes |
gulati |
| T23691 |
2897-2902 |
PR:000036013 |
denotes |
gen i |
| T96566 |
2906-2910 |
G_3;PG_10;PR:000003622 |
denotes |
nver |
| T277 |
2917-2930 |
PR:000036008 |
denotes |
angiotensin I |
| T278 |
2932-2937 |
PR:000036008 |
denotes |
Ang I |
| T279 |
2943-2948 |
PR:000013883 |
denotes |
renin |
| T280 |
2950-2955 |
PR:000036008 |
denotes |
Ang I |
| T43762 |
2969-2981 |
SP_10 |
denotes |
to Ang II vi |
| T281 |
2972-2978 |
PR:000036009 |
denotes |
Ang II |
| T84544 |
2982-2992 |
SP_10;UBERON:0001004 |
denotes |
angiotens |
| T62103 |
2993-3013 |
SP_10 |
denotes |
n-converting enzyme |
| T45099 |
3015-3023 |
SP_10 |
denotes |
CE), whi |
| T96697 |
3031-3039 |
SP_10 |
denotes |
hydrolyz |
| T282 |
3031-3041 |
MOP:0000619 |
denotes |
hydrolyzes |
| T67126 |
3041-3045 |
G_3;PG_10;PR:000003622 |
denotes |
bra |
| T283 |
3042-3052 |
CHEBI:3165;CHEBI:3165 |
denotes |
bradykinin |
| T70630 |
3055-3064 |
PG_1 |
denotes |
to its in |
| T284 |
3071-3082 |
CHEBI:25212;CHEBI:25212 |
denotes |
metabolites |
| T4074 |
3090-3095 |
NCBITaxon:10239;GO:0035376 |
denotes |
ing i |
| T7619 |
3096-3101 |
GO:0035376 |
denotes |
flamm |
| T1702 |
3111-3123 |
GO:0044164 |
denotes |
pro-inflamm |
| T285 |
3140-3146 |
PR:000036009 |
denotes |
Ang II |
| T51851 |
3154-3159 |
NCBITaxon:10239;GO:0006260 |
denotes |
iated |
| T38954 |
3160-3171 |
GO:0006260 |
denotes |
by Ang II t |
| T286 |
3163-3169 |
PR:000036009 |
denotes |
Ang II |
| T34720 |
3186-3192 |
PR:000036009 |
denotes |
(AT1), |
| T28581 |
3201-3206 |
PR:000003622;G_3;PG_10 |
denotes |
imula |
| T287 |
3210-3221 |
CHEBI:27584;CHEBI:27584 |
denotes |
aldosterone |
| T52593 |
3235-3240 |
NCBITaxon:10239 |
denotes |
m the |
| T288 |
3241-3256 |
UBERON:0001236 |
denotes |
adrenal medulla |
| T289 |
3301-3310 |
UBERON:0002198 |
denotes |
pituitary |
| T53738 |
3306-3310 |
PR:000001251 |
denotes |
tary |
| T290 |
3312-3323 |
CHEBI:27584;CHEBI:27584 |
denotes |
Aldosterone |
| T291 |
3334-3342 |
GO:0016020 |
denotes |
membrane |
| T14088 |
3335-3340 |
PR:000001607 |
denotes |
embra |
| T292 |
3343-3347 |
G_3;PG_10;PR:000003622 |
denotes |
ACE2 |
| T293 |
3348-3358 |
GO:0010467 |
denotes |
expression |
| T294 |
3360-3370 |
UBERON:0001986;PR:000006897 |
denotes |
Endothelin |
| T295 |
3370-3372 |
PR:000006897 |
denotes |
-1 |
| T296 |
3382-3395 |
PR:000036013 |
denotes |
angiotensin 1 |
| T411 |
3391-3396 |
PR:000013883 |
denotes |
in 1- |
| T297 |
3399-3403 |
PR:000036013 |
denotes |
Ang1 |
| T298 |
3411-3424 |
GO:0005576 |
denotes |
extracellular |
| T299 |
3432-3441 |
GO:0065007 |
denotes |
regulated |
| T412 |
3433-3441 |
SP_7 |
denotes |
egulated |
| T413 |
3452-3465 |
PR:000036008 |
denotes |
K)1/ERK2 path |
| T300 |
3456-3460 |
PR:000000103 |
denotes |
ERK2 |
| T414 |
3467-3472 |
PR:000036008 |
denotes |
ys. A |
| T301 |
3471-3477 |
PR:000036009 |
denotes |
Ang II |
| T302 |
3541-3545 |
PR:000036013 |
denotes |
Ang1 |
| T303 |
3552-3556 |
PR:000003622;G_3;PG_10 |
denotes |
ACE2 |
| T415 |
3614-3620 |
PR:000036009 |
denotes |
recep |
| T304 |
3625-3630 |
PR:000036013 |
denotes |
Ang1- |
| T416 |
3642-3646 |
PR:000001251 |
denotes |
e fo |
| T305 |
3669-3674 |
PR:000036008 |
denotes |
Ang I |
| T417 |
3674-3690 |
UBERON:0002053 |
denotes |
to an intermedi |
| T306 |
3694-3700 |
PR:000036012 |
denotes |
Ang1-9 |
| T418 |
3698-3713 |
UBERON:0001236 |
denotes |
-9 or directly |
| T419 |
3730-3741 |
CHEBI:27584;CHEBI:27584 |
denotes |
eptidase ne |
| T307 |
3739-3749 |
PR:000001898 |
denotes |
neprilysin |
| T420 |
3767-3784 |
CHEBI:25354;CHEBI:25354 |
denotes |
ase (PEP). RAS = |
| T308 |
3784-3789 |
PR:000013883 |
denotes |
renin |
