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PubMed:1330924 JSONTXT 2 Projects

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Id Subject Object Predicate Lexical cue
T1 0-141 Sentence denotes Platelet activating factor amplifies human neutrophil adherence to bovine endothelial cells: evidence for a lipoxygenase dependent mechanism.
T1 0-141 Sentence denotes Platelet activating factor amplifies human neutrophil adherence to bovine endothelial cells: evidence for a lipoxygenase dependent mechanism.
T2 142-293 Sentence denotes Platelet activating factor (PAF) is a potent lipid mediator that induces the release of leukotrienes and prostaglandins from various cells and tissues.
T2 142-293 Sentence denotes Platelet activating factor (PAF) is a potent lipid mediator that induces the release of leukotrienes and prostaglandins from various cells and tissues.
T3 294-439 Sentence denotes We examined the capacity of PAF alone and in combination with soluble stimuli to enhance eicosanoid synthesis and adherence of human neutrophils.
T3 294-439 Sentence denotes We examined the capacity of PAF alone and in combination with soluble stimuli to enhance eicosanoid synthesis and adherence of human neutrophils.
T4 440-607 Sentence denotes Neutrophils were preincubated with PAF and washed before exposure to the soluble stimuli F-Met-Leu-Phe (FMLP), calcium ionophore A23187, and phorbol myristate acetate.
T4 440-607 Sentence denotes Neutrophils were preincubated with PAF and washed before exposure to the soluble stimuli F-Met-Leu-Phe (FMLP), calcium ionophore A23187, and phorbol myristate acetate.
T5 608-783 Sentence denotes Preincubation of neutrophils with 1 microM PAF enhanced the release of both LTB4 and LTC4 in response to each of the three agonists, in contrast with the unprimed neutrophils.
T5 608-783 Sentence denotes Preincubation of neutrophils with 1 microM PAF enhanced the release of both LTB4 and LTC4 in response to each of the three agonists, in contrast with the unprimed neutrophils.
T6 784-841 Sentence denotes Priming was specific for PAF since lyso-PAF was inactive.
T6 784-841 Sentence denotes Priming was specific for PAF since lyso-PAF was inactive.
T7 842-1015 Sentence denotes Priming concentrations of PAF also augmented the adherence of neutrophils to endothelium in the presence of the soluble agonists A23187, phorbol myristate acetate, and FMLP.
T7 842-1015 Sentence denotes Priming concentrations of PAF also augmented the adherence of neutrophils to endothelium in the presence of the soluble agonists A23187, phorbol myristate acetate, and FMLP.
T8 1016-1148 Sentence denotes The priming effect of PAF on eicosanoid release and neutrophil adherence was shown to have similar time- and dose-dependent effects.
T8 1016-1148 Sentence denotes The priming effect of PAF on eicosanoid release and neutrophil adherence was shown to have similar time- and dose-dependent effects.
T9 1149-1397 Sentence denotes Further, the priming effects of PAF on adherence could be reversed by preincubation of neutrophils with the lipoxygenase inhibitors nordihydroguiaretic acid and 5,8,11,14-ETYA but not by preincubation with the cyclooxygenase inhibitor indomethacin.
T9 1149-1397 Sentence denotes Further, the priming effects of PAF on adherence could be reversed by preincubation of neutrophils with the lipoxygenase inhibitors nordihydroguiaretic acid and 5,8,11,14-ETYA but not by preincubation with the cyclooxygenase inhibitor indomethacin.
T10 1398-1519 Sentence denotes These data demonstrate that PAF amplifies neutrophil adherence to endothelium through a lipoxygenase dependent mechanism.
T10 1398-1519 Sentence denotes These data demonstrate that PAF amplifies neutrophil adherence to endothelium through a lipoxygenase dependent mechanism.